T cell fate determination: a multi-omics approach

Gust lecture: Ellen A. Robey

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T cell fate determination: a multi-omics approach

The development of thymocytes into CD4 and CD8 T cells is a classic model of lineage commitment, but the mechanism remains unclear. Together with my collaborators, we have jointly analyzed single-cell RNA and protein measurements to construct a timeline of CD4 versus CD8 T-cell development, identifying drivers of differential lineage commitment.

Organizer

UiO FOCIS CoE
Published Oct. 14, 2021 3:09 PM - Last modified Oct. 15, 2021 3:34 PM