Digital Public Defence: Anupam Chandra

Cand. med. Anupam Chandra at Institute of Clinical Medicine will be defending the thesis “Fatty acids and cardiovascular risk factors in a Norwegian general population. Data from the Akershus Cardiac Examination (ACE) 1950 Study” for the degree of PhD (Philosophiae Doctor).

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Photo: Øystein Horgmo, UiO

The public defence will be held as a video conference over Zoom.
The digital public defence will follow regular procedure as far as possible, hence it will be open to the public and the audience can ask ex auditorio questions when invited to do so.

Click here to participate in the public defence

Download Zoom here


Digital Trial Lecture – time and place

See Digital Trial Lecture.

Adjudication committee

  • First opponent: Professor Bruce Griffin, University of Surrey
  • Second opponent: Professor Sam Riahi, Aalborg University Hospital
  • Third member and chair of the evaluation committee: Professor Kirsten Bjørklund Holven, University of Oslo

Chair of the Defence

Professor II Jørgen Jahnsen, University of Oslo

Principal Supervisor

Professor II My Svensson, University of Oslo


 A total of 3,706 participants, born in 1950 and residing in Akershus County were enrolled. All participants underwent clinical examination and blood sampling. Plasma levels of marine n-3 PUFAs, LA and iTFAs were analyzed by gas chromatography.

High plasma marine n-3 PUFA levels were associated with lower serum triglycerides, glycated hemoglobin, body mass index (BMI), serum creatinine, C-reactive protein levels and higher levels of high-density lipoprotein cholesterol.

Similarly, high plasma levels of LA were associated with lower fasting plasma glucose, serum triglycerides, BMI, low-density lipoprotein cholesterol levels and blood pressure.

Plasma iTFA levels were low and inversely associated with serum triglycerides, fasting plasma glucose levels, BMI, blood pressure and CRP levels. Participants with high compared to low plasma iTFA levels were more educated, had a lower prevalence of smoking and consumed alcohol less often.

Our findings signal that a high intake of marine n-3 PUFAs and LA might benefit CV health.

Plasma iTFA levels were low and inversely associated with CV risk factors, findings which were likely confounded by lifestyle related variables. Overall, our findings related to iTFA suggest that the current low iTFA intake in Norway does no longer pose a threat to CV health.

Additional information

Contact the research support staff.

Published Oct. 9, 2020 12:28 PM - Last modified Oct. 26, 2020 9:33 AM