Digital public defence: Anders Johan Haugen
Cand.med. Anders Johan Haugen at Institute of Clinical Medicine will be defending the thesis Cardiovascular outcomes in living kidney donors for the degree of PhD (Philosophiae Doctor).
Photo: Amalie Huth Hovland, UiO
The public defence will be held as a video conference over Zoom.
The defence will follow regular procedure as far as possible, hence it will be open to the public and the audience can ask ex auditorio questions when invited to do so.
Digital trial lecture - time and place
- First opponent: Associate Professor Cecilia Montgomery Øien, Norwegian University of Science and Technology, Trondheim
- Second opponent: Post Doc Ilkka Helantera, University of Helsinki, Finland
- Third member and chair of the evaluation committee: Associate Professor Kristina Haugaa, Institute of Clinical Medicine, University of Oslo
Chair of defence
Associate Professor Elisabeth Qvigstad, Institute of Clinical Medicine, University of Oslo
Geir Mjøen, Oslo University Hospital
Long-term consequences of kidney donation has not been fully studied.
We have investigated prevalence of common diseases among kidney donors, and assessed the risk of hypertension, ischemic heart disease, diabetes and cancer long after donation compared with healthy controls.
We analyzed a cohort with more than 1000 donors and 16000 healthy controls with a follow up period of more than 11 years. In the statistical analysis we used stratified logistic regression to calculated risk estimates, adjusted for different covariates.
After long-term follow up we found a significantly increased risk of hypertension and ischemic heart disease among donors compared with healthy controls. These findings are important for the future selection and long term follow up of donors.
In one of the studies we performed a survival analysis among donors with hypertension at donation, compared with donors with normal blood pressure. We did not find a significantly increased long-term mortality among the hypertensive donors. This result support the use of older donors with hypertension at donation.
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