Digital Public Defence: Elma Jelin

Master of Clinical Nursing Science Elma Jelin at Institute of Clinical Medicine will be defending the thesis "Patient Reported Outcome Measures in Treatment of Neovascular Age-related Macular Degeneration" for the degree of PhD (Philosophiae Doctor).

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Photo: Geir Aksel Qvale

The public defence will be held as a video conference over Zoom.

The defence will follow regular procedure as far as possible, hence it will be open to the public and the audience can ask ex auditorio questions when invited to do so.

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Due to copyright reasons, an electronic copy of the thesis must be ordered from the faculty. In order for the faculty to have time to process the order, it must be received by the faculty no later than 2 days prior to the public defence. Orders received later than 2 days before the defence will not be processed. Inquiries regarding the thesis after the public defence must be addressed to the candidate.

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Adjudication committee

  • First opponent: Clinical Professor Torben Lykke Sørensen, University of Copenhagen, Denmark
  • Second opponent: Professor Madeleine Zetterberg, University of Gothenburg, Sweden
  • Third member and chair of the evaluation committee: Professor John-Anker Zwart, Institute of Clinical Medicine, University of Oslo

Chair of defence

Associate Professor Elisabeth Qvigstad, Institute of Clinical Medicine, University of Oslo

Principal supervisor

Professor II Morten C. Moe, Institute of Clinical Medicine, University of Oslo


Neovascular age-related macular degeneration (nAMD) is causing a progressive central vision loss. Intravitreal anti–vascular endothelial growth factor (anti-VEGF) treatment is often effective, but requires frequent injections for years. Knowledge about what is important according to nAMD patients requiring frequent injections is limited. In this project, we aimed to explore patient-reported outcome measures (PROM) during treatment of nAMD.  We identified the most important dimensions during treatment according to patients and developed a new PROM, Dimensions of importance in treatment of nAMD (DITAMD). We found that patients, in general were satisfied with their treatment. However, five key-areas of improvement were identified including preserving vision, pain relief, early access to treatment, information about the diagnosis and treatment as well visual aids. We further followed 197 patients during the first year of treatment. There were significant improvements in visual acuity, self-reported visual function and symptom state. However, these results were depending on whether therapy was given to the best or worst seeing eye. If only the worst seeing eye was treated, there was no significant change in patient-reported visual function despite a significant improvement in visual acuity. 

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Published June 9, 2021 11:07 AM - Last modified June 23, 2021 10:11 AM