Guest lecture - Frank Tacke
Hepatic macrophage heterogeneity in liver diseases – from pathogenesis to novel therapeutic strategies
Frank Tacke is professor of medicine at the Dept. of Gastroenterology, Metabolic Diseases and Intensive Care Medicine, University Hospital Aachen, Germany. He is currently guest professor at the Norwegian PSC Research Center (NoPSC).
His research interests are: Clinical and Experimental Hepatology, Liver Immunology, Viral Hepatitis, Gastroenterology, Critical Care Medicine, and Monocyte/Macrophage Biology.
For the last several years, important lines of research in his research team included the regulation of inflammatory responses in the liver, novel imaging approaches to dissect immune cell subsets in injured liver, factors driving the progression to fibrosis and cancer, targeting these cellular or molecular mechanisms by nanoparticles and the translation into clinics (biomarkers + therapy). He has been furthermore involved in several clinical trials, mainly focussed on improving therapies for acute liver failure, chronic hepatitis B, hepatitis C, liver cirrhosis and hepatocellular carcinoma.