Discovery of cancer cell programmes and their intersections

Specific tasks include:

• Genetic screens for oncogene- and non-oncogene pathways.
• Identification of protein-protein networks in cancer cells
• Screening for mechanisms in microenvironmental support of tumours
• Screening for factors involved in cancer cell migration and invasion
• Screening for regulators of cellular self-eating (autophagy)
• Generation of data models and methodology for detecting cross-talk between cancer cell programmes