Petter Angell Olsen

Researcher and Facility Manager
Image of Petter Angell Olsen
Mobile phone +47 95163299
Room 1295
Username
Visiting address Domus Medica Sognsvannsveien 9 0372 Oslo Norway
Postal address Hybrid Technology Hub Institute of Basic Medical Sciences Sognsvannsveien 9

Academic interests

  • Implementation of stem cells on microfluidic chip systems.

  • Cell signaling.

  • Genome editing technologies.

Background

PhD in Molecular Biology - University of Oslo (2006).
Thesis: "Targeted sequence alterations in the genomes of mammalian cells mediated by oligonucleotides".
 
Cand. Scient. - University of Tromsø (1998).
Thesis: "Effects of SV40 small tumor antigen on serum response element mediated transcription".
 

Biomedical Laboratory Scientist - Sør-Trøndelag University College (1995).
Thesis: "Creation of HTML documents for use in the World Wide Web - An educational tool in medical biology".

Publications

  • Kwak, Dongho; Olsen, Petter Angell; Danielsen, Anne & Jensenius, Alexander Refsum (2022). A trio of biological rhythms and their relevance in rhythmic mechanical stimulation of cell cultures. Frontiers in Psychology. ISSN 1664-1078. 13. doi: 10.3389/fpsyg.2022.867191. Full text in Research Archive
  • Olsen, Petter Angell & Krauss, Stefan Johannes Karl (2021). The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates. Genes. ISSN 2073-4425. 12(12). doi: 10.3390/genes12121920. Full text in Research Archive
  • Mygland, Line; Mahmuda, Shoshy; Strand, Martin Frank; Olsen, Petter Angell; Aizenshtadt, Aleksandra & Lund, Kaja [Show all 21 contributors for this article] (2021). Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines. iScience. ISSN 2589-0042. 24(7). doi: 10.1016/j.isci.2021.102807. Full text in Research Archive
  • Abadpour, Shadab; Aizenshtadt, Aleksandra; Olsen, Petter Angell; Shoji, Kayoko; Wilson, Steven Ray Haakon & Krauss, Stefan [Show all 7 contributors for this article] (2020). Pancreas-on-a-Chip Technology for Transplantation Applications. Current Diabetes Reports. ISSN 1534-4827. 20. doi: 10.1007/s11892-020-01357-1. Full text in Research Archive
  • Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina & Olsen, Petter Angell [Show all 19 contributors for this article] (2020). Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Communications Biology. ISSN 2399-3642. 3. doi: 10.1038/s42003-020-0916-2. Full text in Research Archive
  • Solberg, Nina; Melheim, Maria; Strand, Martin Frank; Olsen, Petter Angell & Krauss, Stefan (2019). MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition. Cancers. ISSN 2072-6694. 11(2), p. 1–19. doi: 10.3390/cancers11020164. Full text in Research Archive
  • Solberg, Nina Therese; Waaler, Jo; Iversen, Kaja Lund; Mygland, Line; Olsen, Peter Angell & Krauss, Stefan (2018). TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer. Molecular Cancer Research. ISSN 1541-7786. 16(3). doi: 10.1158/1541-7786.MCR-17-0362.
  • Solberg, Nina T.; Waaler, Jo; Lund, Kaja; Mygland, Line; Olsen, Petter A. & Krauss, Stefan (2017). TANKYRASE inhibition enhances the antiproliferative effect of PI3K and EGFR inhibition, mutually affecting β-CATENIN and AKT signaling in colorectal cancer. Molecular Cancer Research. ISSN 1541-7786. 16(3), p. 543–553. doi: 10.1158/1541-7786.MCR-17-0362.
  • Lund, Kaja; Olsen, Cathrine Elisabeth; Wong, Judith Jing Wen; Olsen, Petter Angell; Solberg, Nina Therese & Høgset, Anders [Show all 8 contributors for this article] (2017). 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. Journal of Experimental & Clinical Cancer Research. ISSN 1756-9966. 36, p. 1–18. doi: 10.1186/s13046-017-0662-6.
  • Anumala, Upendra Rao; Waaler, Jo; Nkizinkiko, Yves; Ignatev, Alexander; Lazarow, Katina & Lindemann, Peter [Show all 15 contributors for this article] (2017). Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. Journal of Medicinal Chemistry. ISSN 0022-2623. 60(24), p. 10013–10025. doi: 10.1021/acs.jmedchem.7b00883.
  • Olsen, Peter Angell; Solberg, Nina; Lund, Kaja; Vehus, Tore; Gelazauskaite, Monika & Wilson, Steven Ray Haakon [Show all 7 contributors for this article] (2014). Implications of targeted genomic disruption of β-catenin in B×PC-3 pancreatic adenocarcinoma cells. PLOS ONE. ISSN 1932-6203. 9(12). doi: 10.1371/journal.pone.0115496.
  • Røberg-Larsen, Hanne; Lund, Kaja; Vehus, Tore; Solberg, Nina; Vesterdal, Caroline & Misaghian, Dorna [Show all 10 contributors for this article] (2014). Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols. Journal of Lipid Research. ISSN 0022-2275. 55(7), p. 1531–1536. doi: 10.1194/jlr.D048801.
  • Røberg-Larsen, Hanne; Strand, Martin Frank; Grimsmo, Anders; Olsen, Peter Angell; Dembinski, Jennifer & Rise, Frode [Show all 10 contributors for this article] (2012). High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry. Journal of Chromatography A. ISSN 0021-9673. 1255, p. 291–297. doi: 10.1016/j.chroma.2012.02.002.
  • Olsen, Peter Angell; Gelazauskaite, Monika; Randøl, Markus & Krauss, Stefan (2010). Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction. BMC Molecular Biology. ISSN 1471-2199. 11. doi: 10.1186/1471-2199-11-35.
  • Olsen, Peter Angell; Solhaug, Anita; Booth, James; Gelazauskaite, Monika & Krauss, Stefan (2009). Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases. DNA Repair. ISSN 1568-7864. 8(3), p. 298–308. doi: 10.1016/j.dnarep.2008.11.011.
  • Olsen, Peter Angell; Randøl, Markus; Luna, Gomez Luisa; Brown, Tom & Krauss, Stefan (2005). Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends. Journal of Gene Medicine. ISSN 1099-498X. 7(12), p. 1534–1544.
  • Johannessen, Mona; Olsen, Petter Angell; Sørensen, Rita Irene; Johansen, Bjarne; Seternes, Ole Morten & Moens, Ugo Lionel (2003). A role of the TATA box and the general co-activator hTAFII130/135 in promoter-specific trans-activation by simian virus 40 small t antigen. Journal of General Virology. ISSN 0022-1317. 84, p. 1887–1897. doi: 10.1099/vir.0.19057-0.
  • Olsen, Petter A.; McKeen, C. & Krauss, Stefan (2003). Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter. Gene Therapy. ISSN 0969-7128. 10, p. 1830–1840.
  • Johannessen, Mona; Olsen, Petter Angell; Johansen, Bjarne; Seternes, Ole Morten & Moens, Ugo Lionel (2003). Activation of the coactivator foru-and-a-half-LIM-only protein FHL2 and the c-fos promoter through inhibition of protein phosphatase 2A. Biochemical Pharmacology. ISSN 0006-2952. 65, p. 1317–1328.

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  • Olsen, Peter Angell; Lund, Kaja & Krauss, Stefan (2015). Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells. Genomics Data. ISSN 2213-5960. 4, p. 150–152. doi: 10.1016/j.gdata.2015.04.010.
  • Olsen, Peter Angell (2006). Targeted sequence alterations in the genomes of mammaliancells mediated by oligonucleotides. Unipub forlag. ISSN 82-8072-845-7.

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Published Jan. 31, 2019 2:27 PM - Last modified May 25, 2022 10:19 AM