Petter Angell Olsen

Researcher and Facility Manager
Image of Petter Angell Olsen
Mobile phone +47 95 16 32 99
Room 1295
Visiting address Domus Medica Sognsvannsveien 9 0372 Oslo Norway
Postal address Hybrid Technology Hub Institute of Basic Medical Sciences Sognsvannsveien 9

Academic interests

  • Implementation of stem cells on microfluidic chip systems.

  • Cell signaling.

  • Genome editing technologies.


PhD in Molecular Biology - University of Oslo (2006).
Thesis: "Targeted sequence alterations in the genomes of mammalian cells mediated by oligonucleotides".
Cand. Scient. - University of Tromsø (1998).
Thesis: "Effects of SV40 small tumor antigen on serum response element mediated transcription".

Biomedical Laboratory Scientist - Sør-Trøndelag University College (1995).
Thesis: "Creation of HTML documents for use in the World Wide Web - An educational tool in medical biology".


  • Abadpour, Shadab; Aizenshtadt, Aleksandra; Olsen, Petter Angell; Shoji, Kayoko; Wilson, Steven Ray Haakon; Krauss, Stefan & Scholz, Hanne Bjørnson (2020). Pancreas-on-a-Chip Technology for Transplantation Applications. Current Diabetes Reports.  ISSN 1534-4827.  20 . doi: 10.1007/s11892-020-01357-1 Full text in Research Archive.
  • Waaler, Jo; Mygland, Line; Tveita, Anders Aune; Strand, Martin Frank; Solberg, Nina; Olsen, Petter Angell; Aizenshtadt, Aleksandra; Fauskanger, Marte; Lund, Kaja; Mahmuda, Shoshy (Brinch, Shoshy Alam); Lycke, Eric Maximilian; Dybing, Elisabeth; Nygaard, Vegard; Bøe, Sigurd; Heintz, Karen Marie; Hovig, Eivind; Hammarström, Clara Louise; Corthay, Alexandre & Krauss, Stefan (2020). Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models. Communications Biology.  ISSN 2399-3642.  3 . doi: 10.1038/s42003-020-0916-2 Full text in Research Archive.
  • Solberg, Nina; Melheim, Maria; Strand, Martin Frank; Olsen, Petter Angell & Krauss, Stefan (2019). MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition. Cancers.  ISSN 2072-6694.  11(2), s 1- 19 . doi: 10.3390/cancers11020164 Full text in Research Archive.
  • Solberg, Nina Therese; Waaler, Jo; Iversen, Kaja Lund; Mygland, Line; Olsen, Peter Angell & Krauss, Stefan (2018). TANKYRASE Inhibition Enhances the Antiproliferative Effect of PI3K and EGFR Inhibition, Mutually Affecting β-CATENIN and AKT Signaling in Colorectal Cancer. Molecular Cancer Research.  ISSN 1541-7786.  16(3), s 1541 . doi: 10.1158/1541-7786.MCR-17-0362
  • Anumala, Upendra Rao; Waaler, Jo; Nkizinkiko, Yves; Ignatev, Alexander; Lazarow, Katina; Lindemann, Peter; Olsen, Petter Angell; Murthy, Sudarshan; Obaji, Ezeogo; Majouga, Alexander G; Leonov, Sergey; von Kries, Jens Peter; Lehtiö, Lari; Krauss, Stefan & Nazare, Marc (2017). Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach. Journal of Medicinal Chemistry.  ISSN 0022-2623.  60(24), s 10013- 10025 . doi: 10.1021/acs.jmedchem.7b00883
  • Lund, Kaja; Olsen, Cathrine Elisabeth; Wong, Judith Jing Wen; Olsen, Petter Angell; Solberg, Nina Therese; Høgset, Anders; Krauss, Stefan & Selbo, Pål Kristian (2017). 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. Journal of Experimental & Clinical Cancer Research.  ISSN 1756-9966.  36, s 1- 18 . doi: 10.1186/s13046-017-0662-6
  • Solberg, Nina T.; Waaler, Jo; Lund, Kaja; Mygland, Line; Olsen, Petter A. & Krauss, Stefan (2017). TANKYRASE inhibition enhances the antiproliferative effect of PI3K and EGFR inhibition, mutually affecting β-CATENIN and AKT signaling in colorectal cancer. Molecular Cancer Research.  ISSN 1541-7786.  16(3), s 543- 553 . doi: 10.1158/1541-7786.MCR-17-0362
  • Olsen, Peter Angell; Solberg, Nina; Lund, Kaja; Vehus, Tore; Gelazauskaite, Monika; Wilson, Steven Ray Haakon & Krauss, Stefan (2014). Implications of targeted genomic disruption of β-catenin in B×PC-3 pancreatic adenocarcinoma cells. PLOS ONE.  ISSN 1932-6203.  9(12) . doi: 10.1371/journal.pone.0115496
  • Røberg-Larsen, Hanne; Lund, Kaja; Vehus, Tore; Solberg, Nina; Vesterdal, Caroline; Misaghian, Dorna; Olsen, Peter Angell; Krauss, Stefan; Wilson, Steven Ray Haakon & Lundanes, Elsa (2014). Highly automated nano-LC/MS-based approach for thousand cell-scale quantification of side chain-hydroxylated oxysterols. Journal of Lipid Research.  ISSN 0022-2275.  55(7), s 1531- 1536 . doi: 10.1194/jlr.D048801
  • Røberg-Larsen, Hanne; Strand, Martin Frank; Grimsmo, Anders; Olsen, Peter Angell; Dembinski, Jennifer; Rise, Frode; Lundanes, Elsa; Greibrokk, Tyge; Krauss, Stefan & Wilson, Steven Ray Haakon (2012). High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry. Journal of Chromatography A.  ISSN 0021-9673.  1255, s 291- 297 . doi: 10.1016/j.chroma.2012.02.002
  • Olsen, Peter Angell; Gelazauskaite, Monika; Randøl, Markus & Krauss, Stefan (2010). Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction. BMC Molecular Biology.  ISSN 1471-2199.  11 . doi: 10.1186/1471-2199-11-35
  • Olsen, Peter Angell; Solhaug, Anita; Booth, James; Gelazauskaite, Monika & Krauss, Stefan (2009). Cellular responses to targeted genomic sequence modification using single-stranded oligonucleotides and zinc-finger nucleases. DNA Repair.  ISSN 1568-7864.  8(3), s 298- 308 . doi: 10.1016/j.dnarep.2008.11.011
  • Olsen, Peter Angell; Randøl, Markus; Luna, Gomez Luisa; Brown, Tom & Krauss, Stefan (2005). Genomic sequence correction by single-stranded DNA oligonucleotides: role of DNA synthesis and chemical modifications of the oligonucleotide ends. Journal of Gene Medicine.  ISSN 1099-498X.  7(12), s 1534- 1544
  • Johannessen, Mona; Olsen, Petter Angell; Johansen, Bjarne; Seternes, Ole Morten & Moens, Ugo Lionel (2003). Activation of the coactivator foru-and-a-half-LIM-only protein FHL2 and the c-fos promoter through inhibition of protein phosphatase 2A. Biochemical Pharmacology.  ISSN 0006-2952.  65, s 1317- 1328
  • Olsen, Petter A.; McKeen, C. & Krauss, Stefan (2003). Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter. Gene Therapy.  ISSN 0969-7128.  10, s 1830- 1840
  • Johannessen, Mona; Olsen, Petter Angell; Sørensen, Rita Irene; Johansen, Bjarne; Seternes, Ole Morten & Moens, Ugo Lionel (2003). A role of the TATA box and the general co-activator hTAFII130/135 in promoter-specific trans-activation by simian virus 40 small t antigen. Journal of General Virology.  ISSN 0022-1317.  84, s 1887- 1897 . doi: 10.1099/vir.0.19057-0

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  • Olsen, Peter Angell; Lund, Kaja & Krauss, Stefan (2015). Expression profiling of wild type and β-catenin gene disrupted human BxPC-3 pancreatic adenocarcinoma cells. Genomics Data.  ISSN 2213-5960.  4, s 150- 152 . doi: 10.1016/j.gdata.2015.04.010
  • Olsen, Peter Angell (2006). Targeted sequence alterations in the genomes of mammaliancells mediated by oligonucleotides.

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Published Jan. 31, 2019 2:27 PM - Last modified Mar. 11, 2021 3:44 PM