Xenobiotics and metabolism
Our laboratory "Ruzzin lab" is interested in inter-organ communication and molecular metabolism underlying health and disease.
About the group
An originality of our research is to use xenobiotics (especially environmental pollutants) to affect the biological functions of organs and then explore novel metabolic signalling pathways.
Currently, we are working along two main axes;
- The metabolic roles of the fibroblast growth factor 19 (FGF19), a hormone secreted by the small intestine.
- Microbiota metabolites and their anti-inflammatory and metabolic properties.
Our lab is equipped with most items for modern biochemistry and molecular biology, and we have adapted a broad range of cutting-edge methods from different research fields (metabolism, physiology, nutrition, and environmental toxicology).