Fabian Roth
Faglige interesser
Synapsers fysiologi og plastisitet
Nevrale oscillasjoner
Internevroner i epilepsi
Bakgrunn
2021 - Prosjektleder (Forskningsrådet, FRIPRO), Aksonale dysfunksjoner i Dravet syndrom
2016 - 2021 Postdoktor i Synaptisk fysiologi, Aksonale ionekanalers funksjon.
2009 - 2016 Universitetet i Heidelberg, Fysiologi; Nevrale oscillasjoner, GABA-mediert inhibisjon
Samarbeid
Andreas Draguhn, Heidelberg
Ethan Goldberg, Philadelphia
Utvalgte publikasjoner
Roth, F. C., and Hu, H. (2020). An axon-specific expression of HCN channels catalyzes fast action potential signaling in GABAergic interneurons. Nature Communications, 11, 2248.
Thome, C., Roth, F. C., Obermayer, J., Yanez, A., Draguhn, A., Egorov, A. V. (2018). Synaptic entrainment of ectopic action potential generation in hippocampal pyramidal neurons. Journal of Physiology, 596(21), 5237-5249
Hu, H., Roth, F. C., Vandael, D., Jonas, P. (2018). Complementary Tuning of Na+ and K+ Channel Gating Underlies Fast and Energy-Efficient Action Potentials in GABAergic Interneuron Axons. Neuron, 98(1), 156–165.e6.
Roth, F. C., Beyer, K. M., Both, M., Draguhn, A., Egorov, A. V. (2016) Downstream effects of hippocampal sharp wave ripple oscillations on medial entorhinal cortex layer V neurons in vitro. Hippocampus, 26(12), 1493–1508.
Hick, M., Herrmann, U., Weyer, S. W., Mallm, J.-P., Tschäpe, J.-A., Borgers, M., Mercken, M., Roth, F. C., Draguhn, A., Slomianka, L., Wolfer, D. P., Korte, M., Müller, U. C. (2015). Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity. Acta Neuropathol, 129(1), 21–37.
Nordström, V., Willershäuser, M., Herzer, S., Rozman, J., Bohlen und Halbach, von, O., Meldner, S., Rothermel, U., Kaden, S. Roth, F. C., Waldeck, C., Gretz, N., de Angelis, M.H., Draguhn, A., Klingenspor, M., Gröne, H.-J., Jennemann, R. (2013). Neuronal Expression of Glucosylceramide Synthase in Central Nervous System Regulates Body Weight and Energy Homeostasis. PLoS Biol., 11(3), e1001506.
Roth, F. C. & Draguhn, A. (2012). GABA Metabolism and Transport: Effects on Synaptic Efficacy. Neural Plasticity, 2012, 805830.
Reichinnek, S., Kameke, von, A., Hagenston, A. M., Freitag, E., Roth, F. C., Bading, H., et al. (2012). Reliable optical detection of coherent neuronal activity in fast oscillating networks in vitro. NeuroImage, 60(1), 139–152.
Roth, F. C., and Laberge, F. (2011). High convergence of olfactory and vomeronasal influence in the telencephalon of the terrestrial salamander Plethodon shermani. Neuroscience, 177, 148–158.