Jon Loge

• Holme, Ida K.; Hollund, Henrikke A.; Vandraas, Kathrine Flørenes; Kiserud, Cecilie E.; Reinertsen, Kristin Valborg & Loge, Jon [Vis alle 7 forfattere av denne artikkelen] (2023). Sexual Problems as Late Effects: Awareness and Information Needs Among 1870 Long-term Norwegian Childhood, Adolescent, and Young Adult Cancer Survivors (The NOR-CAYACS Study). Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. doi: 10.1089/jayao.2023.0031. Fulltekst i vitenarkiv
• Alme, Tomas Nordheim; Andreasson, Anna; Asprusten, Tarjei Tørre; Bakken, Anne Karen; Beadsworth, Michael BJ & Boye, Birgitte [Vis alle 51 forfattere av denne artikkelen] (2023). Chronic fatigue syndromes: real illnesses that people can recover from. Scandinavian Journal of Primary Health Care. ISSN 0281-3432. 41(4), s. 372–376. doi: 10.1080/02813432.2023.2235609. Fulltekst i vitenarkiv Vis sammendrag

  The ‘Oslo Chronic Fatigue Consortium’ consists of researchers and clinicians who question the current narrative that chronic fatigue syndromes, including post-covid conditions, are incurable diseases. Instead, we propose an alternative view, based on research, which offers more hope to patients. Whilst we regard the symptoms of these conditions as real, we propose that they are more likely to reflect the brain's response to a range of biological, psychological, and social factors, rather than a specific disease process. Possible causes include persistent activation of the neurobiological stress response, accompanied by associated changes in immunological, hormonal, cognitive and behavioural domains. We further propose that the symptoms are more likely to persist if they are perceived as threatening, and all activities that are perceived to worsen them are avoided. We also question the idea that the best way to cope with the illness is by prolonged rest, social isolation, and sensory deprivation.Instead, we propose that recovery is often possible if patients are helped to adopt a less threatening understanding of their symptoms and are supported in a gradual return to normal activities. Finally, we call for a much more open and constructive dialogue about these conditions. This dialogue should include a wider range of views, including those of patients who have recovered from them.

• Diep, Phoi Phoi; Rüegg, Corina Silvia; Dirdal, Marta Maria; Brinch, Lorentz; BØ, KRISTINE & Fosså, Kristian [Vis alle 17 forfattere av denne artikkelen] (2022). Graft-Versus-Host-Disease and Health-Related Quality of Life in Young Long-term Survivors of Cancer and Allogeneic Hematopoietic Stem Cell Transplantation. Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. 12(1), s. 66–75. doi: 10.1089/jayao.2021.0196.
• Smeland, Knut Bjøro; Holte, Harald; Fagerli, Unn-Merete; Bersvendsen, Hanne Skjerven; Hjermstad, Marianne Jensen & Loge, Jon Håvard [Vis alle 13 forfattere av denne artikkelen] (2022). Total late effect burden in long-term lymphoma survivors after high-dose therapy with autologous stem-cell transplant and its effect on health-related quality of life. Haematologica. ISSN 0390-6078. 107(11), s. 2698–2707. doi: 10.3324/haematol.2021.280413. Fulltekst i vitenarkiv Vis sammendrag

  Lymphoma survivors after high-dose therapy with autologous stem-cell transplant (HDT-ASCT) are at risk of several late effects, which might impair their health-related quality of life (HRQoL). We assessed the total late effect burden in this population, and how it affects HRQoL. All lymphoma survivors treated with HDT-ASCT as adults in Norway between 1987 and 2008 were identified, and 271 (68%) attended both a comprehensive clinical assessment and completed a questionnaire. Severity of 45 conditions in 12 organ-system categories were graded as mild, moderate, severe or life-threatening, according to a modified version of CTCAEv4.03. At a median of 8 years after HDT-ASCT, 98% of survivors had at least one moderate or more severe late effect and 56% had severe or life-threatening late effects. Fourteen percent had low, 39% medium and 47% high late effect burden, defined as having moderate or more severe late effects in 0-1, 2-3 and >3 organsystems, respectively. Female sex, increasing age, B-symptoms at diagnosis and >1 treatment line prior to HDT-ASCT were independently associated with having high late effect burden. The survivors had significantly poorer physical and mental HRQoL assessed by the Short Form-36 compared to age- and sex-matched controls. The prevalence of poor physical and mental HRQoL increased with higher late effect burden (both P<0.001), and the low burden group had better physical HRQoL than controls (P<0.001). In conclusion, lymphoma survivors after HDT-ASCT have impaired HRQoL, seemingly driven by a high late effect burden. This highlights the importance of prevention, regular assessments for early detection and treatment of late effects and modifiable risk factors.

• Bye, Asta; Bjerkeset, Ellen; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen & Klepstad, Pål [Vis alle 9 forfattere av denne artikkelen] (2022). Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study. Palliative Medicine Reports (PMR). 3(1), s. 264–271. doi: 10.1089/pmr.2022.0044. Fulltekst i vitenarkiv
• Michelsen, Brigitte; Berget, Kristine Thomassen; Loge, Jon Håvard; Kavanaugh, Arthur & Haugeberg, Glenn (2022). Sex difference in disease burden of inflammatory arthritis patients treated with tumor necrosis factor inhibitors as part of standard care. PLOS ONE. ISSN 1932-6203. 17(5). doi: 10.1371/journal.pone.0266816. Fulltekst i vitenarkiv Vis sammendrag

  s Metrics Comments Media Coverage Abstract Introduction Patients and methods Results Discussion References Reader Comments Figures Abstract Objective Knowledge is needed on the total disease burden across the sexes in inflammatory arthritis (IA). We aimed to compare disease burden, including a broad range of health aspects, across men and women with IA treated with tumor necrosis factor inhibitors (TNFi). Methods Adult outpatients with IA (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis) were included as part of standard care. Patient-reported outcomes, disease activity, TNFi trough levels, calprotectin, Work Productivity and Activity Impairment, comorbidities and cardiovascular risk profile were assessed. Unadjusted comparisons across sexes were done with independent t-test, Mann-Whitney U-test and X2-test and adjusted analyses with General Linear Models and logistic/ordinal logistic regression. Results A total of 305 IA patients were included (167 men, 138 women). A significantly lower proportion of women (45%) than men (59%) were in remission according to disease-specific composite scores (p = 0.02). Women had significantly worse scores on pain, joint pain, fatigue, enthesitis, Health Assessment Questionnaire and Short Form (SF)-36 vitality and social functioning (all p≤0.04). Both sexes had worse SF-36 scale scores than the general population. Women reported more absenteeism (work time missed) and activity impairment. TNFi trough levels, neutralizing antibodies and calprotectin were similar across sexes. A similar total number of comorbidities was seen. Self-reported hypothyroidism was more frequent in women. Men had higher 10-year calculated risk of fatal cardiovascular events. Conclusion Important differences in disease burden between men and women were seen. More attention to sex differences in the follow-up of IA patients is warranted.

• Mellblom, Anneli; Ruud, Ellen; Loge, Jon Håvard; Lie, Hanne Cathrine & Finset, Arnstein (2022). From Observation to Action: Developing and Pilot-Testing a Communication Tool for Follow-up Consultations with Adolescent Cancer Survivors. Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. 11(4), s. 419–426. doi: 10.1089/jayao.2021.0123. Vis sammendrag

  Purpose: Efficient physician communication with adolescent cancer survivors (ACS) during follow-up consultations is important to enable survivors to take responsibility for their health. The present study had two aims: to develop a communication tool to enhance structured consultations and improve clinician communication in follow-up consultations, and to pilot-test the tool in physicians' consultations with ACS. Methods: Clinicians and communication experts collaborated closely to develop the 7 Memory Hooks (7MH) communication tool and a corresponding coding scheme for scoring communication behavior in consultations. Thirty-seven follow-up consultations between ACS and physicians were video-recorded (22 before intervention and 15 after intervention). The intervention consisted of a didactic lecture, a group workshop, and individual coaching to provide feedback to physicians on the communication skills observed in the pre-intervention videos. We then compared physicians' communication behavior both before and after intervention. Results: Fourteen physicians participated in the 7MH training. The mean total score on the 7MH scheme was significantly higher post-intervention compared with pre-intervention (p = 0.001). Six behaviors changed significantly after the intervention. At a group level, physicians were more likely to be alone with the adolescent (p = 0.004) and to prepare the patient for transition to adult heath care (p = 0.040). They asked more often about the patients' expectations (p = 0.007) and resources ((p = 0.019). And they acknowledged patients' concerns more often (p = 0.016) but talked significantly less about physical activity (p = 0.012). Conclusion: A physician communication tool, designed bottom-up and developed in collaboration with the clinic, shows promising effects on physicians' communication behavior at follow-up consultations with ACS

• Dahl, Alv A; Kiserud, Cecilie E.; Fosså, Sophie Dorothea; Loge, Jon Håvard; Reinertsen, Kristin Valborg & Ruud, Ellen [Vis alle 7 forfattere av denne artikkelen] (2022). A study of high neuroticism in long-term survivors of childhood, adolescence, and young adult cancers. Scientific Reports. ISSN 2045-2322. 12(1). doi: 10.1038/s41598-022-15697-3. Fulltekst i vitenarkiv Vis sammendrag

  Neuroticism is a basic personality trait concerning negative feelings under stressful conditions. Our purpose was to examine the rate of high neuroticism and factors associated with high neuroticism in long-term (≥ 5 years) survivors of childhood, adolescent, and young adult cancer (CAYACSs). Norwegian CAYACSs aged 0–39 years when diagnosed and treated between 1985 and 2009 for cancer in childhood/adolescence (0–18 years), or as young adults (19–39 years) and alive in 2015 were mailed a questionnaire. Data from 1629 CAYACSs (481 children/adolescents and 1148 young adults) were analyzed. High neuroticism was found in 44% of survivors of childhood/adolescent cancers versus 34% in survivors of young adult cancer (p < 0.001). The rate of high neuroticism in female CAYACSs was 40% and in males 30% (p < 0.001). The corresponding difference between male survivor group was non-significant. In multivariable analysis, young age at survey, more adverse effects, poor self-rated health, female sex, chronic fatigue, and increased depression remained significantly associated with high neuroticism. Cancer treatment, comorbidity, and lifestyle were significant in bivariate analyses. Cancer at earlier age could increase the risk of high neuroticism among adult survivors. Screening for neuroticism could identify CAYACSs at risk for experiencing multiple health concerns and needing special follow-up attention.

• Dahl, Alv A; Kiserud, Cecilie E.; Fosså, Sophie Dorothea; Loge, Jon Håvard; Reinertsen, Kristin Valborg & Ruud, Ellen [Vis alle 7 forfattere av denne artikkelen] (2021). A controlled study of major depressive episodes in long‐term childhood, adolescence, and young adult cancer survivors (The nor‐cayacs study). Cancers. ISSN 2072-6694. 13:5800(22), s. 1–13. doi: 10.3390/cancers13225800. Fulltekst i vitenarkiv
• Bøhn, Synne-Kristin Hoffart; Lie, Hanne Cathrine; Reinertsen, Kristin Valborg; Fosså, Sophie Dorothea; Haugnes, Hege Sagstuen & Kiserud, Cecilie E. [Vis alle 9 forfattere av denne artikkelen] (2020). Lifestyle among long-term survivors of cancers in young adulthood. Supportive Care in Cancer. ISSN 0941-4355. 29(1), s. 289–300. doi: 10.1007/s00520-020-05445-6. Fulltekst i vitenarkiv Vis sammendrag

  Abstract Purpose To investigate lifestyle in a population-based sample of long-term (≥ 5 years since diagnosis) young adult cancer survivors (YACSs), and explore factors associated with not meeting the lifestyle guidelines for physical activity (PA), body mass index (BMI), and smoking. Methods YACSs (n = 3558) diagnosed with breast cancer (BC), colorectal cancer (CRC), non-Hodgkin lymphoma (NHL), acute lymphoblastic leukemia (ALL), or localized malignant melanoma (MM) between the ages of 19 and 39 years and treated between 1985 and 2009 were invited to complete a mailed questionnaire. Survivors of localized MM treated with limited skin surgery served as a reference group for treatment burden. Results In total, 1488 YACSs responded (42%), and 1056 YACSs were evaluable and included in the present study (74% females, average age at survey 49 years, average 15 years since diagnosis). Forty-four percent did not meet PA guidelines, 50% reported BMI ≥ 25 and 20% smoked, with no statistically significant differences across diagnostic groups. Male gender, education ≤ 13 years, comorbidity, lymphedema, pain, chronic fatigue, and depressive symptoms were associated with not meeting single and/or an increasing number of lifestyle guidelines. Conclusion A large proportion of long-term YACSs do not meet the lifestyle guidelines for PA, BMI, and/or smoking. Non-adherence to guidelines is associated with several late effects and/or comorbidities that should be considered when designing lifestyle interventions for YACSs.

• Mellblom, Anneli; Kiserud, Cecilie E.; Rueegg, Corina Silvia; Ruud, Ellen; Loge, Jon Håvard & Fosså, Sophie Dorothea [Vis alle 7 forfattere av denne artikkelen] (2020). Self-reported late effects and long-term follow-up care among 1889 long-term Norwegian Childhood, Adolescent, and Young Adult Cancer Survivors (the NOR-CAYACS study). Supportive Care in Cancer. ISSN 0941-4355. s. 1–11. doi: 10.1007/s00520-020-05790-6. Fulltekst i vitenarkiv
• Dahl, Alv A; Grotmol, Kjersti Støen; Hjermstad, Marianne Jensen; Kiserud, Cecilie E. & Loge, Jon Håvard (2020). Norwegian reference data on the Fatigue Questionnaire and the Patient Health Questionnaire-9 and their interrelationship. Annals of General Psychiatry. ISSN 1744-859X. 19:60, s. 1–9. doi: 10.1186/s12991-020-00311-5. Fulltekst i vitenarkiv
• Fosså, Alexander; Smeland, Knut Bjøro; Fluge, Øystein; Tronstad, Karl Johan; Loge, Jon Håvard & Midtun, Øyvind [Vis alle 8 forfattere av denne artikkelen] (2020). Metabolic analysis of amino acids and vitamin B6 pathways in lymphoma survivors with cancer related chronic fatigue. PLOS ONE. ISSN 1932-6203. 15:e0227384(1), s. 1–16. doi: 10.1371/journal.pone.0227384. Fulltekst i vitenarkiv
• Krogstad, Hilde; Loge, Jon Håvard; Grotmol, Kjersti S.; Kaasa, Stein; Kiserud, Cecilie E. & Salvesen, Øyvind [Vis alle 7 forfattere av denne artikkelen] (2020). Symptoms in the general Norwegian adult population - prevalence and associated factors. BMC Public Health. ISSN 1471-2458. 20. doi: 10.1186/s12889-020-09109-2. Fulltekst i vitenarkiv
• Fredheim, Olav Magnus; Skurtveit, Svetlana; Loge, Jon Håvard; Sjøgren, Per; Handal, Marte & Hjellvik, Vidar (2020). Prescription of analgesics to long-term survivors of cancer in early adulthood, adolescence and childhood in Norway: a national cohort study. Pain. ISSN 0304-3959. 161(5), s. 1083–1091. doi: 10.1097/j.pain.0000000000001800. Fulltekst i vitenarkiv
• Storås, Anne Marie Holck; Sanda, Martin G.; Garin, Olatz; Chang, Peter; Patil, Dattatraya & Crociani, Catrina [Vis alle 10 forfattere av denne artikkelen] (2019). A prospective study of patient reported urinary incontinence among American, Norwegian and Spanish men 1 year after prostatectomy. Asian Journal of Urology (AJU). ISSN 2214-3882. s. 1–9. doi: 10.1016/j.ajur.2019.08.001. Fulltekst i vitenarkiv
• Lie, Hanne Cathrine; Rueegg, Corina Silvia; Fosså, Sophie Dorothea; Loge, Jon Håvard; Ruud, Ellen & Kiserud, Cecilie E. (2019). Limited evidence of non-response bias despite modest response rate in a nationwide survey of long-term cancer survivors?results from the NOR-CAYACS study. Journal of cancer survivorship. ISSN 1932-2259. 13(3), s. 353–363. doi: 10.1007/s11764-019-00757-x. Fulltekst i vitenarkiv
• Dahl, Alv A; Fosså, Sophie Dorothea; Lie, Hanne Cathrine; Loge, Jon Håvard; Reinertsen, Kristin Valborg & Ruud, Ellen [Vis alle 7 forfattere av denne artikkelen] (2019). Employment Status and Work Ability in Long-Term Young Adult Cancer Survivors. Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. 8(3), s. 304–311. doi: 10.1089/jayao.2018.0109. Fulltekst i vitenarkiv
• Gjerset, Gunhild Maria; Kiserud, Cecilie E.; Loge, Jon Håvard; Fosså, Sophie Dorothea; Wisløff, Torbjørn & Gudbergsson, Sævar Berg [Vis alle 8 forfattere av denne artikkelen] (2019). Changes in fatigue, health-related quality of life and physical activity after a one-week educational program for cancer survivors. Acta Oncologica. ISSN 0284-186X. 58(5), s. 682–689. doi: 10.1080/0284186X.2018.1562210. Fulltekst i vitenarkiv
• Bøhn, Synne-Kristin Hoffart; Thorsen, Lene; Kiserud, Cecilie E.; Fosså, Sophie Dorothea; Lie, Hanne Cathrine & Loge, Jon Håvard [Vis alle 9 forfattere av denne artikkelen] (2019). Chronic fatigue and associated factors among long-term survivors of cancers in young adulthood. Acta Oncologica. ISSN 0284-186X. 58(5), s. 753–762. doi: 10.1080/0284186X.2018.1557344. Fulltekst i vitenarkiv Vis sammendrag

  Background: Chronic fatigue (CF) is scarcely explored among young adult cancer survivors (YACSs), and more knowledge is needed to develop targeted interventions for YACSs with CF. The present study aimed to investigate the prevalence of CF and associated factors in YACSs. Also, the change of fatigue with time was explored. Material and methods: The present cross-sectional study is part of a nation-wide population based survey of Norwegian survivors of cancer in childhood, adolescence, and young adulthood (The NOR-CAYACS study).YACSs diagnosed at the age of 19–39 years with breast cancer stage ≤ III (BC), colorectal cancer (CRC), non-Hodgkin lymphoma (NHL), acute lymphoblastic leukemia, or non-metastatic malignant melanoma (MM) were included 5–30 years after diagnosis. Survivors of MM treated with limited surgery were included as a reference group. CF was assessed by the Fatigue Questionnaire. Logistic regression analyses were performed to identify factors associated with CF. Results: In total, 1488 survivors completed the questionnaire (a response rate of 42%), of which 1088 were eligible for the present study. Overall, 25% reported CF. CF was significantly more prevalent among survivors of BC (29%) (p < .001), CRC (29%) (p = .001) and NHL (27%) (p = .003) than among survivors of MM (15%). CF was associated with systemic treatment combined with surgery and/or radiotherapy (p = .018), comorbidity (p = .038), pain (p = .002), numbness in hands/feet (p = .046), and depressive symptoms (p < .001) in the multivariable model. Among survivors with CF, 60% reported that they had been tired since cancer treatment, and among these, 65% reported worsening or no change of fatigue with time. Conclusion: One of four YACSs reported CF 15 years from diagnosis (mean). CF was associated with several possibly treatable factors. Health professionals involved in the follow-up of YACSs should have knowledge of CF and approaches to manage it.

• Kaasa, Stein; Loge, Jon Håvard; Aapro, Matti S.; Albreht, Tit; Anderson, Rebecca & Bruera, Eduardo [Vis alle 30 forfattere av denne artikkelen] (2018). Integration of oncology and palliative care: a Lancet Oncology Commission. The Lancet Oncology. ISSN 1470-2045. 19(11), s. e588–e653. doi: 10.1016/S1470-2045(18)30415-7. Fulltekst i vitenarkiv
• Smeland, Knut Bjøro; Loge, Jon Håvard; Aass, Hans Christian Dalsbotten; Aspelin, Trude; Bersvendsen, Hanne Skjerven & Bolstad, Nils [Vis alle 16 forfattere av denne artikkelen] (2018). Chronic fatigue is highly prevalent in survivors of autologous stem cell transplantation and associated with IL-6, neuroticism, cardiorespiratory fitness, and obesity. Bone Marrow Transplantation. ISSN 0268-3369. s. 1–4. doi: 10.1038/s41409-018-0342-y. Fulltekst i vitenarkiv
• Habberstad, Ragnhild H; Frøseth, Trude Camilla Salvesen; Aass, Nina Kathrine; Abramova, Tatiana Mikhailovna; Baas, Theo & Mørkeset, Siri Tessem [Vis alle 24 forfattere av denne artikkelen] (2018). The Palliative Radiotherapy and Inflammation Study (PRAIS) - Protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain. BMC Palliative Care. ISSN 1472-684X. 17(110). doi: 10.1186/s12904-018-0362-9. Fulltekst i vitenarkiv
• Krogstad, Hilde; Sundt-Hansen, Stine Marie; Hjermstad, Marianne Jensen; Hågensen, Liv Ågot; Kaasa, Stein & Loge, Jon Håvard [Vis alle 9 forfattere av denne artikkelen] (2018). Usability testing of EirV3-a computer-based tool for patient-reported outcome measures in cancer. Supportive Care in Cancer. ISSN 0941-4355. s. 1–10. doi: 10.1007/s00520-018-4435-3. Fulltekst i vitenarkiv
• Petersen, Morten Aa.; Aaronson, Neil K.; Arraras, Juan I; Chie, Wei-Chu; Conroy, Thierry & Costantini, Anna [Vis alle 29 forfattere av denne artikkelen] (2018). The EORTC CAT Core?The computer adaptive version of the EORTC QLQ-C30 questionnaire. European Journal of Cancer. ISSN 0959-8049. 100, s. 8–16. doi: 10.1016/j.ejca.2018.04.016. Fulltekst i vitenarkiv
• Michelsen, Brigitte; Uhlig, Till; Sexton, Joseph; Heijde, Desirée van der; Hammer, Hilde Berner & Kristianslund, Eirik [Vis alle 13 forfattere av denne artikkelen] (2018). Health-related quality of life in patients with psoriatic and rheumatoid arthritis: Data from the prospective multicentre NOR-DMARD study compared with Norwegian general population controls. Annals of the Rheumatic Diseases. ISSN 0003-4967. 77(9), s. 1290–1294. doi: 10.1136/annrheumdis-2018-213286. Fulltekst i vitenarkiv
• Berger, Ola; Grønberg, Bjørn Henning; Loge, Jon Håvard; Kaasa, Stein & Sand, Kari (2018). Cancer patients' knowledge about their disease and treatment before, during and after treatment: a prospective, longitudinal study. BMC Cancer. ISSN 1471-2407. 18:381, s. 1–11. doi: 10.1186/s12885-018-4164-5. Fulltekst i vitenarkiv
• Grotmol, Kjersti Støen; Lie, Hanne Cathrine; Loge, Jon Håvard; Aass, Nina Kathrine; Haugen, Dagny Faksvåg & Stone, Patrick C [Vis alle 8 forfattere av denne artikkelen] (2018). Patients with advanced cancer and depression report a significantly higher symptom burden than non-depressed patients. Palliative & Supportive Care. ISSN 1478-9515. s. 1–7. doi: 10.1017/S1478951517001183. Fulltekst i vitenarkiv
• Johannsdottir, Inga Marie; Loge, Jon Håvard; Kiserud, Cecilie E.; Karlstad, Øystein & Skurtveit, Svetlana (2018). Increased prescription rates of anxiolytics and hypnotics to survivors of cancer in childhood, adolescence, and young adulthood — A population-based study. Pediatric Blood & Cancer. ISSN 1545-5009. 65(2). doi: 10.1002/pbc.26860. Fulltekst i vitenarkiv
• Johannsdottir, Inga Marie; Hamre, Hanne Mari; Fosså, Sophie Dorothea; Loge, Jon Håvard; Drolsum, Liv & Lund, May-Brith [Vis alle 8 forfattere av denne artikkelen] (2017). Adverse Health Outcomes and Associations with Self-Reported General Health in Childhood Lymphoma Survivors. Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. 6(3), s. 470–476. doi: 10.1089/jayao.2017.0018.
• Grotmol, Kjersti Støen; Lie, Hanne Cathrine; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Currow, David & Kaasa, Stein [Vis alle 9 forfattere av denne artikkelen] (2017). Depression-A Major Contributor to Poor Quality of Life in Patients With Advanced Cancer. Journal of Pain and Symptom Management. ISSN 0885-3924. 54(6), s. 889–897. doi: 10.1016/j.jpainsymman.2017.04.010. Fulltekst i vitenarkiv
• Reinertsen, Kristin Valborg; Loge, Jon Håvard; Brekke, Mette & Kiserud, Cecilie E. (2017). Kronisk tretthet hos voksne kreftoverlevere. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 137(21). doi: 10.4045/tidsskr.17.0040.
• Mellblom, Anneli; Ruud, Ellen; Loge, Jon Håvard & Lie, Hanne Cathrine (2017). Do negative emotions expressed during follow-up consultations with adolescent survivors of childhood cancer reflect late effects? Patient Education and Counseling. ISSN 0738-3991. 100(11), s. 2098–2101. doi: 10.1016/j.pec.2017.06.008. Fulltekst i vitenarkiv
• Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen & Kaasa, Stein [Vis alle 9 forfattere av denne artikkelen] (2017). Norwegian reference values for the Short-Form Health Survey 36: development over time. Quality of Life Research. ISSN 0962-9343. s. 1–12. doi: 10.1007/s11136-017-1684-4. Fulltekst i vitenarkiv
• Krogstad, Hilde; Brunelli, Cinzia; Sand, Kari; Andersen, Eivind; Garresori, Herish & Halvorsen, Tarje Onsøien [Vis alle 13 forfattere av denne artikkelen] (2017). Development of EirV3: A computer-based tool for patient-reported outcome measures in cancer. JCO Clinical Cancer Informatics. ISSN 2473-4276. 2017(1), s. 1–14. doi: 10.1200/CCI.17.00051. Fulltekst i vitenarkiv Vis sammendrag

  Background. Immediate transfer of patient reported outcome measures (PROMs) for use in medical consultations is facilitated by electronic assessments. Objective. Describe the rationale and development towards Eir version3 (V3), a computer-based symptom assessment tool for cancer; with emphasis on content and user-friendliness. Methods. Eir’s specifications and content were developed through multi-professional, stepwise and iterative processes (2013-16), with literature reviews on traditional and electronic assessment and classification methods, formative iterative usability tests with end-users and patient preferences for paper versus electronic assessments. Results. EirV3 has two modules: Eir-Patient for PROMs registration on tablets and Eir-Doctor for presentation of PROMs in a user-friendly interface on computers. Eir-Patient starts with 19 common cancer symptoms followed by specific, in-depth questions for endorsed symptoms. The pain section includes a body map for pain location and intensity, whereas physical functioning, nutritional intake and wellbeing are standard questions for all. Data are wirelessly transferred to Eir-Doctor. Symptoms with intensity scores >3 (0-10 scale) are marked in red, with brighter colors corresponding to higher intensity, supplemented with graphs displaying symptom development over time. Usability results showed that patients and health care providers found Eir intuitive, easy to use and relevant. When comparing PROM-assessments on paper versus tablets (N=114), 19% preferred paper, 41% and 40% preferred tablets or had no preference. Median intraclass-correlation coefficients between paper and tablets was excellent (0.815). Conclusions. Iterative test-rounds followed by continuous improvements led to a user-friendly, applicable EirV3, developed for and by end-users. EirV3 is undergoing international testing of clinical and cross-cultural adaptability. Keywords: Patient reported outcome measures, PROMS, computers, usability, feasibility

• Lie, Hanne Cathrine; Mellblom, Anneli; Brekke, Mette; Finset, Arnstein; Fosså, Sophie Dorothea & Kiserud, Cecilie E. [Vis alle 8 forfattere av denne artikkelen] (2017). Experiences with late effects-related care and preferences for long-term follow-up care among adult survivors of childhood lymphoma. Supportive Care in Cancer. ISSN 0941-4355. 25(8), s. 2445–2454. doi: 10.1007/s00520-017-3651-6.
• Thorsen, Lene; Kirkegaard, Camilla; Loge, Jon Håvard; Kiserud, Cecilie E.; Johansen, Merethe Lia & Gjerset, Gunhild Maria [Vis alle 10 forfattere av denne artikkelen] (2017). Feasibility of a physical activity intervention during and shortly after chemotherapy for testicular cancer. BMC Research Notes. ISSN 1756-0500. 10(214). doi: 10.1186/s13104-017-2531-y. Fulltekst i vitenarkiv
• Gjerset, Gunhild Maria; Loge, Jon Håvard; Kiserud, Cecilie E.; Fosså, Sophie Dorothea; Gudbergsson, Sævar Berg & Oldervoll, Line Merethe [Vis alle 8 forfattere av denne artikkelen] (2017). Perceived needs for different components in a rehabilitation program among cancer survivors with chronic fatigue compared to survivors without chronic fatigue. Acta Oncologica. ISSN 0284-186X. 56(2), s. 245–253. doi: 10.1080/0284186X.2016.1266091. Fulltekst i vitenarkiv
• Kaasa, Stein; Knudsen, Anne Kari; Lundeby, Tonje & Loge, Jon Håvard (2017). Integraton between oncology and palliatve care: A plan for the next decade? Tumori (Milano). ISSN 0300-8916. 103(1), s. 1–8. doi: 10.5301/tj.5000602. Fulltekst i vitenarkiv
• Reinertsen, Kristin Valborg; Engebråten, Olav; Loge, Jon Håvard; Småstuen, Milada Cvancarova; Naume, Bjørn & Wist, Erik [Vis alle 10 forfattere av denne artikkelen] (2017). Fatigue During and After Breast Cancer Therapy—A Prospective Study. Journal of Pain and Symptom Management. ISSN 0885-3924. 53(3), s. 551–560. doi: 10.1016/j.jpainsymman.2016.09.011. Fulltekst i vitenarkiv
• Johannsdottir, Inga Marie; Karlstad, Øystein; Loge, Jon Håvard; Fosså, Sophie Dorothea; Kiserud, Cecilie E. & Skurtveit, Svetlana (2017). Prescriptions of Antidepressants to Survivors of Cancer in Childhood, Adolescence, and Young Adulthood: A Population-Based Study. Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. 6(1), s. 120–126. doi: 10.1089/jayao.2016.0041.
• Fredheim, Olav Magnus Søndenå; Brelin, Siri; Hjermstad, Marianne Jensen; Loge, Jon Håvard; Aass, Nina Kathrine & Johannessen, Tom Børge [Vis alle 7 forfattere av denne artikkelen] (2017). Prescriptions of analgesics during complete disease trajectories in patients who are diagnosed with and die from cancer within the five-year period 2005-2009. European Journal of Pain. ISSN 1090-3801. 21(3), s. 530–540. doi: 10.1002/ejp.956.
• Loge, Jon Håvard; Hjermstad, Marianne Jensen & Løhre, Erik Torbjørn (2016). Delirium. I Kaasa, Stein & Loge, Jon Håvard (Red.), Palliasjon. Nordisk lærebok. 3. utgave. Gyldendal Akademisk. ISSN 9788205488403. s. 501–510.
• Brelin, Siri; Fredheim, Olav Magnus; Loge, Jon Håvard; Skurtveit, Svetlana; Johannesen, Tom Børge & Aass, Nina Kathrine [Vis alle 8 forfattere av denne artikkelen] (2016). Opioids for outpatients with cancer in their last year of life: A nationwide pharmacoepidemiological study. Journal of Opioid Management. ISSN 1551-7489. 12(1), s. 25–36. doi: 10.5055/jom.2016.0309.
• Korsvold, Live; Mellblom, Anneli; Lie, Hanne Cathrine; Ruud, Ellen; Loge, Jon Håvard & Finset, Arnstein (2016). Patient-provider communication about the emotional cues and concerns of adolescent and young adult patients and their family members when receiving a diagnosis of cancer. Patient Education and Counseling. ISSN 0738-3991. 99(10), s. 1576–1583. doi: 10.1016/j.pec.2016.03.028.
• Fosså, Sophie Dorothea; Storås, Anne Marie Holck; Steinsvik, Eivind Andreas Svaboe; Myklebust, Tor Åge; Eri, Lars Magne & Loge, Jon Håvard [Vis alle 7 forfattere av denne artikkelen] (2016). Psychometric testing of the Norwegian version of the Expanded Prostate Cancer Index Composite 26-item version (EPIC-26). Scandinavian Journal of Urology. ISSN 2168-1805. 50(4), s. 280–285. doi: 10.3109/21681805.2016.1163617.
• Korsvold, Live; Lie, Hanne Cathrine; Mellblom, Anneli; Ruud, Ellen; Loge, Jon Håvard & Finset, Arnstein (2016). Tailoring the delivery of cancer diagnosis to adolescent and young adult patients displaying strong emotions: An observational study of two cases. International Journal of Qualitative Studies on Health and Well-being. ISSN 1748-2623. 11. doi: 10.3402/qhw.v11.30763. Fulltekst i vitenarkiv
• Hjermstad, Marianne Jensen; Kaasa, Stein; Caraceni, Augusto; Loge, Jon Håvard; Pedersen, Tore & Haugen, Dagny Faksvåg [Vis alle 7 forfattere av denne artikkelen] (2016). Characteristics of breakthrough cancer pain and its influence on quality of life in an international cohort of patients with cancer. BMJ Supportive & Palliative Care. ISSN 2045-435X. 6(3), s. 344–352. doi: 10.1136/bmjspcare-2015-000887. Vis sammendrag

  Objectives: Breakthrough cancer pain (BTP) represents a treatment challenge. Objectives were to examine the prevalence and characteristics of BTP in an international sample of patients with cancer, and to investigate the relationship between BTP and quality of life (QoL). Methods: This was an observational cross-sectional multicentre study. Participating patients completed self-report questionnaires on a touch-screen laptop computer, including the Brief Pain Inventory, Alberta Breakthrough Pain Assessment Tool (ABPAT) and European Organisation for Research and Treatment of Cancer 30-item Core Quality of Life Questionnaire (EORTC QLQ-C30). The study was performed in 17 centres in 8 countries and involved 4 languages (Norwegian, Italian, German and English). Results: Records from a convenience sample of 978 patients with advanced cancer were analysed; mean age was 62.2 years, 48.3% were women and 84.4% had metastatic disease. A total of 296 patients (30%) had no pain, defined as worst pain in the past 24 hours <1 on a 0–10 scale. Of the 682 patients with a pain score ≥1, 393 (58%) reported no BTP on the screening item, while 289 (30%) confirmed flare ups of BTP. Patients with BTP reported significantly higher pain intensity scores (<0.001) than patients without BTP; 57.1% of patients rated BTP at its worst as being severe: ≥7 on a 0–10 scale. Time from onset to peak intensity was <10 min for 42.9%, and average time to pain relief was 27.1 min. BTP was commonly triggered by medication wearing off (28%). Patients with BTP had significantly worse mean outcomes on 10 of 15 functional and symptom scales of the EORTC QLQ-C30 (<0.001). Severe pain intensity in the last week was a powerful predictor of BTP (OR 4.1) and poor QoL (OR 1.9). Conclusions: BTP is highly prevalent with prolonged episodes despite analgaesics, and has a pervasive impact on QoL. Patients reporting high pain intensity should be carefully evaluated for BTP and efficacy of analgaesic treatment, to provide optimal pain management and improve QoL.

• Storås, Anne Marie Holck; Sanda, Martin G.; Boronat, Olatz Garin; Chang, Peter; Patil, Dattatraya & Crociani, Catrina [Vis alle 10 forfattere av denne artikkelen] (2016). Erectile Dysfunction and Sexual Problems Two to Three Years after Prostatectomy among American, Norwegian, and Spanish Patients. Clinical Genitourinary Cancer. ISSN 1558-7673. 14(3), s. e265–e273. doi: 10.1016/j.clgc.2015.10.009.
• Jeppesen, Elisabeth; Bjelland, Ingvar; Fosså, Sophie Dorothea; Loge, Jon Håvard & Dahl, Alv A (2016). Health-related quality of life in teenagers with a parent with cancer. European Journal of Oncology Nursing. ISSN 1462-3889. 22, s. 46–53. doi: 10.1016/j.ejon.2016.03.004.
• Murbræch, Klaus; Wethal, Torgeir; Smeland, Knut Bjøro; Holte, Harald; Loge, Jon Håvard & Holte, Espen [Vis alle 10 forfattere av denne artikkelen] (2016). Valvular Dysfunction in Lymphoma Survivors Treated with Autologous Stem Cell Transplantation A National Cross-Sectional Study. JACC Cardiovascular Imaging. ISSN 1936-878X. 9(3), s. 230–239. doi: 10.1016/j.jcmg.2015.06.028.
• Smeland, Knut Bjøro; Kiserud, Cecilie E.; Lauritzsen, Grete Fossum; Blystad, Anne Kirsti; Fagerli, Unn-Merete & Falk, Ragnhild Sørum [Vis alle 14 forfattere av denne artikkelen] (2016). A national study on conditional survival, excess mortality and second cancer after high dose therapy with autologous stem cell transplantation for non-Hodgkin lymphoma. British Journal of Haematology. ISSN 0007-1048. 173(3), s. 432–443. doi: 10.1111/bjh.13965.
• Brenne, Elisabeth; Loge, Jon Håvard; Lie, Hanne Cathrine; Hjermstad, Marianne Jensen; Fayers, Peter & Kaasa, Stein (2016). The Edmonton Symptom Assessment System: Poor performance as a screener for major depression in patients with incurable cancer. Palliative Medicine. ISSN 0269-2163. 30(6), s. 587–598. doi: 10.1177/0269216315620082. Fulltekst i vitenarkiv
• Mellblom, Anneli; Korsvold, Live; Ruud, Ellen; Lie, Hanne Cathrine; Loge, Jon Håvard & Finset, Arnstein (2016). Sequences of talk about emotional concerns in follow-up consultations with adolescent childhood cancer survivors. Patient Education and Counseling. ISSN 0738-3991. 99(1), s. 77–84. doi: 10.1016/j.pec.2015.07.021.
• Petersen, Morten Aa.; Aaronson, Neil K.; Chie, Wei-Chu; Conroy, Thierry; Costantini, Anna & Hammerlid, Eva [Vis alle 12 forfattere av denne artikkelen] (2016). Development of an item bank for computerized adaptive test (CAT) measurement of pain. Quality of Life Research. ISSN 0962-9343. 25(1), s. 1–11. doi: 10.1007/s11136-015-1069-5.
• Mellblom, Anneli; Korsvold, Live; Finset, Arnstein; Loge, Jon Håvard; Ruud, Ellen & Lie, Hanne Cathrine (2015). Providing information about late effects during routine follow-up consultations between pediatric oncologists and adolescent survivors: A video-based, observational study. Journal of Adolescent and Young Adult Oncology. ISSN 2156-5333. 4(4), s. 200–208. doi: 10.1089/jayao.2015.0037. Vis sammendrag

  Purpose: Information about late effects is a prerequisite for survivors of childhood cancers to engage in selfmanagement of their health. Yet, many lack such knowledge. This study investigated to what extent: (1) potential late effects were discussed with adolescent and young adult (AYA)-aged survivors (of pediatric cancer), and (2) information about late effects was provided by the pediatric oncologists (POs) during routine follow-up consultations. Methods: Consultations were recorded with 10 POs and 66 adolescents, aged 12–20 years, treated for leukemia (72.7%) or lymphoma (21.2%), or who had received hematopoietic stem-cell transplantation for a benign disease (7.6%). Discussions of potential late effects were identified and coded, and then the amount of information about late effects provided was categorized into three levels: none, basic, and extended information. Results: Potential late effects were discussed in 85% of the consultations. Of these, 71% were PO initiated, and 60% concerned existing health problems. The POs provided none, basic, and extended information about late effects in 41%, 30%, and 29% of these discussions. Patients’ age, time since treatment, and risk of late effects were not associated with amount of potential late effects discussed, but the type of potential late effect (physical vs. psychosocial and current vs. future risk) and PO were. Conclusion: Potential late effects were frequently discussed, thus providing ample opportunity to provide information about late effects to adolescent cancer survivors. The observed PO variability in providing such information indicates a need for standardization of information practices.

• Loge, Jon Håvard & Kaasa, Stein (2015). The Future of Oncology Palliative Care. I Alt-Epping, Bernd & Nauck, Friedemann (Red.), Palliative Care in Oncology. Springer. ISSN 978-3-662-46201-0. s. 299–399. doi: 10.1007/978-3-662-46202-7_18.
• Selland, Mette; Holte, Harald; Bjøro, Trine; Schreiner, Thomas; Bollerslev, Jens & Loge, Jon Håvard [Vis alle 8 forfattere av denne artikkelen] (2015). Chronic fatigue is prevalent and associated with hormonal dysfunction in long-term non-Hodgkin lymphoma survivors treated with radiotherapy to the head and neck region. Leukemia and Lymphoma. ISSN 1042-8194. 56(12), s. 3306–3314. doi: 10.3109/10428194.2015.1036258. Vis sammendrag

  The purposes of this study were to assess the prevalence of chronic fatigue (CF) in irradiated survivors of non-Hodgkin lymphoma, analyze for associations between hormonal dysfunction and CF, and to investigate the associations between CF and functioning. Invited survivors were all treated with radiation to the head and neck region, with or without additional chemotherapy. The participants (n =98) responded to questionnaires measuring CF, mental distress (HADS), and functioning (SF-36), and had blood drawn for analyses of four hormonal axes. Hormonal status was categorized as normal, hormone dysfunction in one or more axes, or hormone replacement therapy. A total of 29% of the survivors had CF. In multivariate analyses there was an increased risk of CF among survivors with untreated hormone dysfunction (OR 3.87, 95% CI: 1.20–12.51, P 0.02). Survivors on hormone substitution did not have increased risk for CF compared to survivors with normal hormonal status. CF was significantly associated with reduced functioning.

• Gjerset, Gunhild Maria; Loge, Jon Håvard; Gudbergsson, Sævar Berg; Bye, Asta; Fosså, Sophie Dorothea & Oldervoll, Line Merethe [Vis alle 9 forfattere av denne artikkelen] (2015). Lifestyles of cancer survivors attending an inpatient educational program—a cross-sectional study. Supportive Care in Cancer. ISSN 0941-4355. 24, s. 1527–1536. doi: 10.1007/s00520-015-2936-x.
• Murbræch, Klaus; Smeland, Knut Bjøro; Holte, Harald; Loge, Jon Håvard; Lund, May Brit & Wethal, Torgeir [Vis alle 13 forfattere av denne artikkelen] (2015). Heart failure and asymptomatic left ventricular systolic dysfunction in lymphoma survivors treated with autologous stem-cell transplantation: A national cross-sectional study. Journal of Clinical Oncology. ISSN 0732-183X. 33(24), s. 2683–2691. doi: 10.1200/JCO.2015.60.8125.
• Lie, Hanne Cathrine; Loge, Jon Håvard; Fosså, Sophie Dorothea; Hamre, Hanne Mari; Hess, Siri Lothe & Mellblom, Anneli [Vis alle 8 forfattere av denne artikkelen] (2015). Providing information about late effects after childhood cancer: Lymphoma survivors' preferences for what, how and when. Patient Education and Counseling. ISSN 0738-3991. 98(5), s. 604–611. doi: 10.1016/j.pec.2015.01.016.
• Dahl, Sigrun; Loge, Jon Håvard; Berge, Viktor; Dahl, Alv A; Småstuen, Milada C & Fosså, Sophie Dorothea (2015). Influence of radical prostatectomy for prostate cancer on work status and working life 3 years after surgery. Journal of cancer survivorship. ISSN 1932-2259. 9(2), s. 172–179. doi: 10.1007/s11764-014-0399-6.
• Selland, Mette; Bjøro, Trine; Furre, Torbjørn; Schreiner, Thomas; Bollerslev, Jens & Fosså, Sophie Dorothea [Vis alle 9 forfattere av denne artikkelen] (2015). Hormonal dysfunction is frequent in cancer survivors treated with radiotherapy to the head and neck region. Journal of cancer survivorship. ISSN 1932-2259. 9(4), s. 630–640. doi: 10.1007/s11764-015-0439-x.
• Smeland, Knut Halvor Bjøro; Kiserud, Cecilie E.; Lauritzsen, Grete Fossum; Fagerli, Unn-Merete; Falk, Ragnhild Sørum & Fluge, Øystein [Vis alle 12 forfattere av denne artikkelen] (2015). Conditional survival and excess mortality after high-dose therapy with autologous stem cell transplantation for adult refractory or relapsed Hodgkin lymphoma in Norway. Haematologica. ISSN 0390-6078. 100(6), s. e240–e243. doi: 10.3324/haematol.2014.119214. Fulltekst i vitenarkiv
• Lie, Hanne Cathrine; Hjermstad, Marianne Jensen; Fayers, Peter; Finset, Arnstein; Kaasa, Stein & Loge, Jon Håvard (2015). Depression in advanced cancer - Assessment challenges and associations with disease load. Journal of Affective Disorders. ISSN 0165-0327. 173, s. 176–184. doi: 10.1016/j.jad.2014.11.006.
• Ramstad, Kjersti; Loge, Jon Håvard; Jahnsen, Reidun & Diseth, Trond H (2015). Self-reported mental health in youth with cerebral palsy and associations to recurrent musculoskeletal pain. Disability and Rehabilitation. ISSN 0963-8288. 37(2), s. 144–150. doi: 10.3109/09638288.2014.913703.
• Kiserud, Cecilie E.; Selland, Mette; Holte, Harald; Fosså, Alexander; Fosså, Sophie Dorothea & Bollerslev, Jens [Vis alle 8 forfattere av denne artikkelen] (2015). Fatigue in male lymphoma survivors differs between diagnostic groups and is associated with latent hypothyroidism. Acta Oncologica. ISSN 0284-186X. 54(1), s. 49–59. doi: 10.3109/0284186X.2014.948057.
• Gudbergsson, SB; Dahl, Alv A; Loge, Jon Håvard; Thorsen, Lene; Oldervoll, Line Merethe & Grov, Ellen Karine (2015). What is covered by "Cancer Rehabilitation" in PubMed? A review of randomized controlled trials 1990-2011. Journal of Rehabilitation Medicine. ISSN 1650-1977. 47(2), s. 97–106. doi: 10.2340/16501977-1902. Fulltekst i vitenarkiv
• Kiserud, Cecilie E.; Dahl, Alv A; Loge, Jon Håvard & Fosså, Sophie Dorothea (2014). Cancer Survivorship in Adults. Recent Results in Cancer Research. ISSN 0080-0015. 197, s. 103–120. doi: 10.1007/978-3-642-40187-9_8.
• Zeller, Bernward; Ruud, Ellen; Loge, Jon Håvard; Kanellopoulos, Adriani; Hamre, Hanne Mari & Godang, Kristin [Vis alle 7 forfattere av denne artikkelen] (2014). Chronic Fatigue in Adult Survivors of Childhood Cancer: Associated Symptoms, Neuroendocrine Markers, and Autonomic Cardiovascular Responses. Psychosomatics. ISSN 0033-3182. 55(6), s. 621–629. doi: 10.1016/j.psym.2013.12.005.
• Jeppesen, Elisabeth; Bjelland, Ingvar; Fosså, Sophie Dorothea; Loge, Jon Håvard; Sørebø, Øystein & Dahl, Alv A (2014). Does a parental history of cancer moderate the associations between impaired health status in parents and psychosocial problems in teenagers: a HUNT study. Cancer Medicine. ISSN 2045-7634. 3(4), s. 919–926. doi: 10.1002/cam4.245. Fulltekst i vitenarkiv
• Oldervoll, Line Merethe; Thorsen, Lene; Kaasa, Stein; Fosså, Sophie Dorothea; Dahl, Alv A & Småstuen, MC [Vis alle 10 forfattere av denne artikkelen] (2014). Inpatient versus outpatient rehabilitation after breast and gynecological cancers – a comparative study. International Journal of Physical Medicine & Rehabilitation. ISSN 2329-9096. 2(187).
• Zeller, Bernward; Loge, Jon Håvard; Kanellopoulos, Adriani; Hamre, Hanne Mari; Wyller, Vegard Bruun & Ruud, Ellen (2014). Chronic fatigue in long-term survivors of childhood Lymphomas and Leukemia: Persistence and associated clinical factors. Journal of Pediatric Hematology/Oncology. ISSN 1077-4114. 36(6), s. 438–444. doi: 10.1097/MPH.0000000000000051.
• Mellblom, Anneli; Finset, Arnstein; Korsvold, Live; Loge, Jon Håvard; Ruud, Ellen & Lie, Hanne Cathrine (2014). Emotional concerns in follow-up consultations between paediatric oncologists and adolescent survivors: A video-based observational study. Psycho-Oncology. ISSN 1057-9249. 23(12), s. 1365–1372. doi: 10.1002/pon.3568.
• Storås, Anne Marie Holck; Sanda, Martin G.; Ferrer, Montse; Loge, Jon Håvard; Dahl, Alv A & Steinsvik, Eivind Andreas Svaboe [Vis alle 9 forfattere av denne artikkelen] (2014). Localized prostate cancer in Norway, the united states, and Spain: Between-country differences of variables before treatment among patients eligible for curative treatment. Clinical Genitourinary Cancer. ISSN 1558-7673. 12(4), s. e117–e125. doi: 10.1016/j.clgc.2013.12.007.
• Dahl, Sigrun; Steinsvik, Eivind Andreas Svaboe; Dahl, Alv A; Loge, Jon Håvard; Småstuen, Milada C & Fosså, Sophie Dorothea (2014). Return to work and sick leave after radical prostatectomy: A prospective clinical study. Acta Oncologica. ISSN 0284-186X. 53(6), s. 744–751. doi: 10.3109/0284186X.2013.844357.
• Berger, Ola; Sand, Kari; Johansen, Ingunn; Loge, Jon Håvard; Kaasa, Stein & Grønberg, Bjørn H. (2014). What Do Cancer Patients and Members of Ethical Review Boards in Norway Consider Important Elements of Informed Consent Documents? AJOB Empirical Bioethics. ISSN 2329-4515. 5(4), s. 1–13. doi: 10.1080/23294515.2014.938199. Vis sammendrag

  Background: The length and content of informed consent documents (ICDs) in clinical trials have increased in recent decades. In Norway, Regional Committees for Medical and Health Research Ethics (RECs) approve ICDs according to national and international guidelines. The aim of this study was to investigate how important members of these committees and cancer patients consider the information elements found in ICDs to be. Methods: Using the Delphi technique, an expert group developed a questionnaire for asking the participants how they rated the importance of 31 information elements, and whether they were familiar with or considered seven terms/phrases commonly used in ICDs difficult to understand. All 123 members of the Norwegian RECs and 200 consecutive cancer patients at the outpatient cancer clinic at St. Olavs Hospital, Trondheim University Hospital, received the questionnaire. Group comparisons were conducted using chi-squared and Fisher`s exact tests. The statistical significance level was defined as p < .01 due to multiple comparisons. Results: The committee members (n = 81) and patients (n = 104) rated almost all (95%) of the information elements as important. Very few (4%) information elements were rated as not important. We did not find any significant differences in the rating of the elements between subgroups of patients, between subgroups of REC members, or between patients and REC members. The patients were not familiar with all terms commonly found in ICDs, and the REC members were not able to predict which terms the patients were familiar with. Patients rated the information elements as more important if they were familiar with the terms used in the respective elements. Conclusions: The participants rated almost all information elements important to include in ICDs, suggesting that ICDs cannot necessarily be shortened by leaving out information elements. Ensuring that patients understand all terms in an ICD appears to be a particularly important part of the informed consent process.

• Janberidze, Elene; Hjermstad, Marianne Jensen; Brunelli, Cinzia; Loge, Jon Håvard; Lie, Hanne Cathrine & Kaasa, Stein [Vis alle 7 forfattere av denne artikkelen] (2014). The use of antidepressants in patients with advanced cancer - results from an international multicentre study. Psycho-Oncology. ISSN 1057-9249. 23(10), s. 1096–1102. doi: 10.1002/pon.3541.

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• Loge, Jon Håvard & Kaasa, Stein (2016). Palliasjon Nordisk lærebok. Gyldendal Akademisk. ISBN 9788205488403. 832 s.
• Kaasa, Stein & Loge, Jon Håvard (2016). Palliasjon. Nordisk lærebok. 3. utgave. Gyldendal Akademisk. ISBN 9788205488403. 832 s.
• Haavet, Ole Rikard; Dahl, Alv A; Aarre, Trond F. & Loge, Jon Håvard (2014). Psykiske problemer i somatisk medisin. Haavet OR. Kap. 44 Somatisk sykdom hos ungdom. Cappelen Damm AS. ISBN 9788202418786.
• Dahl, Alv A; Aare, Trond F & Loge, Jon Håvard (2014). Psykiske reaksjoner ved somatisk sykdom. Cappelen Damm Akademisk. ISBN 9788202418786. 736 s.

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• Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Andersen, Sigve; Brunelli, Cinzia; Dajani, Olav & Ahmed, Herish [Vis alle 20 forfattere av denne artikkelen] (2020). PALLiON - PALLiative care Integrated in ONcology: Study protocol for a Norwegian national cluster-randomized control trial with a complex intervention of early integration of palliative care. Trials. ISSN 1745-6215. 21:303, s. 1–17. doi: 10.1186/s13063-020-4224-4. Fulltekst i vitenarkiv
• Krogstad, Hilde; Sundt-Hansen, Stine Marie; Hjermstad, Marianne Jensen; Hågensen, Liv Ågot; Kaasa, Stein & Loge, Jon Håvard [Vis alle 9 forfattere av denne artikkelen] (2018). Usability testing of EirV3 - a computer-based tool for patient reported outcome measures in cancer. Annals of Oncology. ISSN 0923-7534. 29, s. viii625–viii625. doi: 10.1093/annonc/mdy300.068.
• Krogstad, Hilde; Sundt-Hansen, Stine Marie; Hjermstad, Marianne Jensen; Hågensen, Liv Ågot; Kaasa, Stein & Loge, Jon Håvard [Vis alle 9 forfattere av denne artikkelen] (2018). Usability testing of EirV3 - a computer-based tool for patient reported outcome measures in cancer.
• Sand, Kari; Lie, Hanne Cathrine; Loge, Jon Håvard; Kiserud, Cecilie E. & Lund, Jo-Åsmund (2018). The physician perspective regarding providing information about late-effects to cancer patients and survivors: The dilemma of when and what. A focus group study among Norwegian GPs and oncologists.
• Diep, Phoi Phoi; Melberg, Hans Olav; Brinch, Lorentz; Buechner, Jochen; Fløisand, Yngvar & Gedde-Dahl, Thobias [Vis alle 9 forfattere av denne artikkelen] (2018). Cost-utility of allogeneic hematopoietic stem cell transplantation in Norway. Bone Marrow Transplantation. ISSN 0268-3369. 53(5), s. 657–660. doi: 10.1038/s41409-018-0091-y.
• Sand, Kari; Lie, Hanne Cathrine; Kiserud, Cecilie E.; Loge, Jon Håvard & Lund, Jo-Åsmund (2018). The physician perspective regarding providing information about late-effects to cancer patients and survivors: The dilemma of when and what.
• Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen & Kaasa, Stein [Vis alle 9 forfattere av denne artikkelen] (2017). Correction to: Norwegian reference values for the Short-Form Health Survey 36: development over time. Quality of Life Research. ISSN 0962-9343. s. 1–3. doi: 10.1007/s11136-017-1708-0. Fulltekst i vitenarkiv
• Lundeby, Tonje; Jacobsen, Henrik Børsting; Lundeby, Paul Andreas & Loge, Jon Håvard (2017). Emotions in communication skills training - experiences from general practice to Porsche maintenance. Patient Education and Counseling. ISSN 0738-3991. 100(11), s. 2141–2143. doi: 10.1016/j.pec.2017.06.006.
• Krogstad, Hilde; Brunelli, Cinzia; Garresori, Herish; Kaasa, Stein; Kristensen, Are Korsnes & Loge, Jon Håvard [Vis alle 8 forfattere av denne artikkelen] (2017). A pilot study of electronic vs. paper-and-pencil completion of PROMs in cancer care.
• Didriksen, Mona; Brenne, Anne-Tove; Kaasa, Stein; Loge, Jon Håvard & Sand, Kari (2017). Implementation of Eir – an electronical symptom management tool for cancer patients – at a surgical department: Is it feasible? Vis sammendrag

  BACKGROUND: Eir is a web-based communication platform for symptom assessment and clinical decision support in cancer care. Although Eir has been demonstrated to be a reasonable and feasible part of the symptom management for advanced cancer patients, the knowledge of how to implement this tool into clinical practice is lacking. PURPOSE: The overall aim of this study is to increase the knowledge of success criteria and barriers of implementation of the electronic symptom assessment tool Eir at a surgical department. MATERIAL AND METHODS: This project used a descriptive, qualitative study design, based on semi-structured interviews and observations. 11 patients and 26 health care professionals were included from a surgical department in a local hospital in Norway. RESULTS: Overall, the patients and health care professionals were satisfied with Eir. They found it easy to use, understandable and relevant. The health care professionals considered Eir to improve consultations and to increase the quality of the health care. However, it was emphasized that Eir should be integrated with already existing computer programs in clinical use. It was also a wish from the physicians that decision support should be available for all symptoms addressed in Eir. The health care professionals in this study identified three main categories of success criteria for implementation of Eir: 1) Anchoring in the management, 2) the process manager and nurses’ participation in the implementation process, and 3) perceived high value for clinical work. Also three main categories for barriers for implementation were identified: 1) Inaccessibility of tool, 2) health care professionals’ experience of unfavourable resource allocation in the clinic, and 3) the amount of part-time employees among the nurses. CONCLUSIONS: According to this study, it is feasible to implement Eir at a surgical department since the tool is found easy to use and of clinical value for the users. However, in order to achieve a successful implementation, Eir must be integrated into electronical patient record systems, and designated personnel in the clinic, preferably nurses, must constantly monitor the implementation process. For the latter part to succeed, it is unfavourable that nurses work part-time.

• Krogstad, Hilde; Brunelli, Cinzia; Garresori, Herish; Kaasa, Stein; Kristensen, Are Korsnes & Loge, Jon Håvard [Vis alle 8 forfattere av denne artikkelen] (2017). A pilot study of electronic vs. paper-and-pencil completion of PROMs in cancer care. European Journal of Palliative Care. ISSN 1352-2779. s. 210–210. Vis sammendrag

  Background: Systematic use of Patient-Reported Outcomes Measures (PROMs) is essential for optimal patient care. Electronic PROMs collection may improve symptom assessment due to more efficient data capturing, immediate presentation of results and less response burden as opposed to paper forms. Aims: Aims were to 1) investigate the equivalence of PROMs scores on common cancer symptoms collected in randomized order by paper forms and iPads, 2) assess patient preferences for one of the two assessment modes Methods: A parallel form agreement study was done at six Norwegian hospitals. Patients were approached when coming for a scheduled appointment at the cancer outpatient clinics. After consent they were asked to score the intensity of 19 common cancer symptoms on 0-10 numerical rating scales; 0: no pain, nausea etc. and 10: worst imaginable on paper and iPads. The symptoms were identical to the initial ones used in Eir, an electronic PROMs tool currently undergoing international validation. Patients were randomised to start with either the paper or iPad version, followed by the other version 30 minutes later. Intraclass correlation coefficients (ICC) were used to examine equivalence of paper/iPad scores. Results: Of the included 114 patients, 110 (97%) completed both versions; 59 (54%) on iPad first, 51 (46%) on paper first. Mean age was 64.5 (27-86), median Karnofsky 90 (50-100). GI-cancer was most common (47%) followed by prostate (10%), breast and malignant melanoma (both 9%). 89% had metastatic disease. Overall, the median ICC was 0.815,>0.75 for 14 items and ranging from 0.64 (vomiting) to 0.92 (tiredness). Interquartile range was 0.145. Overall 41% of the patients preferred assessment on iPads, 19% preferred paper, while 40% had no preference. Conclusion: The equivalence of PROMs scores was good, and the majority of patients preferred iPads or had no preference. This is promising, considering the many advantages of electronic assessments.

• Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Grotmol, Kjersti Støen; Kaasa, Stein; Lundeby, Tonje & Seljelid, Berit [Vis alle 8 forfattere av denne artikkelen] (2017). Integration of oncology and palliative care - findings from the PALLiON pre-study survey.
• Kaasa, Stein; Knudsen, Anne Kari; Lundeby, Tonje & Loge, Jon Håvard (2017). Author's reply to: Integration between oncology and palliative care: A plan for the next decade? Tumori (Milano). ISSN 0300-8916. 103(3). doi: 10.5301/tj.5000631.
• Sand, Kari; Lie, Hanne Cathrine; Kiserud, Cecilie E.; Loge, Jon Håvard & Lund, Jo-Åsmund (2016). Barriers and opportunities for long-term follow-up care of cancer survivors. A focus group study among Norwegian general practitioners and oncologists. Vis sammendrag

  Background: Cancer therapy can cause persisting or late-onset health problems, late effects. At present, there is no consensus regarding the appropriate organization and content of follow-up care of cancer survivors with, or at risk for, late effects. The aim of the study is to examine oncologists' and general practitioners’ views and preferences for models of long-term follow-up care of cancer survivors regarding late effects. Methods & Materials: We conducted qualitative, focus groups interviews with GPs and oncologists across Norway. So far, 22 oncologists and 24 GPs have participated in 10 focus groups. Six further focus-group interviews are planned. The interviews were audio-recorded, transcribed and analyzed using principles of content analysis. Results: Preliminary analysis of barriers for long-term follow-up care showed that oncologists seldom meet cancer survivors with late effects in their daily clinical practice, while GPs seldom meet the patient during his/her cancer treatment. Both groups expressed limited knowledge of late effects, available treatment for late effects and rehabilitation options. In order to facilitate better long-term follow-up care, both oncologists and GPs expressed a need for better communication between primary and specialist care. Dedicated survivorship clinics/coordinators would allow for better coordination of care between health care professionals, serve as a place to contact for information and to accumulate important knowledge regarding late effects and rehabilitation services. GPs regard themselves as the main responsible for the follow-up care, as long the oncologists provide specific procedures for follow-up care for each survivor (e.g. survivorship care passport), and the survivors themselves take responsibility for contacting health care providers when necessary. Conclusion: Preliminary analysis indicates that oncologists and GPs supports a shard care model for long term follow-up of cancer survivors in Norway, a model in which the specialist and the primary care physicians have defined responsibilities in survivorship care pathways.

• Kaasa, Stein & Loge, Jon Håvard (2015). Quality of life in palliative care: principles and practice. I Cherny, Nathan; Fallon, Marie; Kaasa, Stein; Portenoy, Russell K. & Currow, David C. (Red.), Oxford Textbook of Palliative Medicine, Fifth Edition. Oxford University Press. ISSN 978-0-19-965609-7. s. 1198–1219.
• Berger, Ola; Sand, Kari; Johansen, Ingunn; Kaasa, Stein; Loge, Jon Håvard & Grønberg, Bjørn Henning (2014). What Do Cancer Patients and Members of Ethical Review Boards in Norway Consider Important Elements in Informed Consent Documents?
• Berger, Ola; Sand, Kari; Johansen, Ingunn; Loge, Jon Håvard; Kaasa, Stein & Grønberg, Bjørn Henning (2014). What Do Cancer Patients and Members of Ethical Review Boards in Norway Consider Important Elements in Informed Consent Documents? Palliative Medicine. ISSN 0269-2163. 28(6). doi: 10.1177/0269216314532748.
• Janberidze, Elene; Hjermstad, Marianne Jensen; Brunelli, Cinzia; Loge, Jon Håvard; Lie, Hanne Cathrine & Kaasa, Stein [Vis alle 7 forfattere av denne artikkelen] (2014). The use of antidepressants in patients with advanced cancer – results from an international multicenter study.

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