Anne Cathrine (Annetine) Staff

• Lorenzon, Aline R.; Moreli, Jusciele Brogin; Melo, Rafaela de Macedo; Namba, Felipe Yukio; Staff, Anne Cathrine; Yung, Hong Wa; Burton, Graham J. & Bevilacqua, Estela (2021). Stromal cell-derived factor (Sdf) 2 and the endoplasmic reticulum stress response of trophoblast cells in gestational diabetes mellitus and in vitro hyperglycaemic condition cp. Current Vascular Pharmacology.  ISSN 1570-1611.  19(2), s 201- 209 . doi: 10.2174/1570161118666200606222123
• Allotey, John; Snell, Kym I.E.; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; von Dadelszen, Peter; Dodds, Julie; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid S.; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony O.; Ramírez, Javier A.; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, AA; Seed, PT; Prefumo, F; da Silva Costa, F; Groen, H; Audibert, F; Masse, J; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, C; Rumbold, Alice R.; Heinonen, Seppo; Askie, LM; Smits, LJ; Vinter, CA; Magnus, Per; Kajantie, Eero Olavi; Villa, PM; Jenum, Anne Karen; Andersen, LB; Norman, JE; Ohkuchi, A; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala M.; Galindo, Alberto; Herraiz, Ignacio; Carbillon,, Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Teede, Helena J.; Browne, Joyce L; Moons, Karel G.M.; Riley, Richard D & Thangaratinam, Shakila (2020). Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. Health Technology Assessment.  ISSN 1366-5278.  24(72) . doi: 10.3310/hta24720 Full text in Research Archive. Show summary

  Background: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. Objectives: To assess the performance of existing pre-eclampsia prediction models and to develop and validate models for pre-eclampsia using individual participant data meta-analysis. We also estimated the prognostic value of individual markers. Design: This was an individual participant data meta-analysis of cohort studies. Setting: Source data from secondary and tertiary care. Predictors: We identified predictors from systematic reviews, and prioritised for importance in an international survey. Primary outcomes: Early-onset (delivery at < 34 weeks' gestation), late-onset (delivery at ≥ 34 weeks' gestation) and any-onset pre-eclampsia. Analysis: We externally validated existing prediction models in UK cohorts and reported their performance in terms of discrimination and calibration. We developed and validated 12 new models based on clinical characteristics, clinical characteristics and biochemical markers, and clinical characteristics and ultrasound markers in the first and second trimesters. We summarised the data set-specific performance of each model using a random-effects meta-analysis. Discrimination was considered promising for C-statistics of ≥ 0.7, and calibration was considered good if the slope was near 1 and calibration-in-the-large was near 0. Heterogeneity was quantified using I 2 and τ2. A decision curve analysis was undertaken to determine the clinical utility (net benefit) of the models. We reported the unadjusted prognostic value of individual predictors for pre-eclampsia as odds ratios with 95% confidence and prediction intervals. Results: The International Prediction of Pregnancy Complications network comprised 78 studies (3,570,993 singleton pregnancies) identified from systematic reviews of tests to predict pre-eclampsia. Twenty-four of the 131 published prediction models could be validated in 11 UK cohorts. Summary C-statistics were between 0.6 and 0.7 for most models, and calibration was generally poor owing to large between-study heterogeneity, suggesting model overfitting. The clinical utility of the models varied between showing net harm to showing minimal or no net benefit. The average discrimination for IPPIC models ranged between 0.68 and 0.83. This was highest for the second-trimester clinical characteristics and biochemical markers model to predict early-onset pre-eclampsia, and lowest for the first-trimester clinical characteristics models to predict any pre-eclampsia. Calibration performance was heterogeneous across studies. Net benefit was observed for International Prediction of Pregnancy Complications first and second-trimester clinical characteristics and clinical characteristics and biochemical markers models predicting any pre-eclampsia, when validated in singleton nulliparous women managed in the UK NHS. History of hypertension, parity, smoking, mode of conception, placental growth factor and uterine artery pulsatility index had the strongest unadjusted associations with pre-eclampsia. Limitations: Variations in study population characteristics, type of predictors reported, too few events in some validation cohorts and the type of measurements contributed to heterogeneity in performance of the International Prediction of Pregnancy Complications models. Some published models were not validated because model predictors were unavailable in the individual participant data. Conclusion: For models that could be validated, predictive performance was generally poor across data sets. Although the International Prediction of Pregnancy Complications models show good predictive performance on average, and in the singleton nulliparous population, heterogeneity in calibration performance is likely across settings.

• Angell, Inga Leena; Nilsen, Morten; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Hedlin, Gunilla; Jonassen, Christine M; Marsland, Benjamin; Nordlund, Björn; Rehbinder, Eva Maria; Schinagl, Carina Madelen; Skjerven, Håvard Ove; Staff, Anne Cathrine; Söderhäll, Cilla; Vettukattil, Muhammad Riyas & Rudi, Knut (2020). De novo species identification using 16S rRNA gene nanopore sequencing. PeerJ.  ISSN 2167-8359.  8:e10029, s 1- 11 . doi: 10.7717/peerj.10029 Full text in Research Archive.
• Berdzuli, Nino; Lomia, Nino; Staff, Anne Cathrine; Kereselidze, Maia; Lazdane, Gunta & Jacobsen, Anne Flem (2020). Maternal mortality in Georgia: Incidence, causes and level of underreporting: A national reproductive age mortality study 2014. International Journal of Women's Health.  ISSN 1179-1411.  12, s 277- 286 . doi: 10.2147/IJWH.S227349 Full text in Research Archive.
• Drabbels, Jos J.M.; Welleweerd, Robert; van Rooy, Inge; Johnsen, Guro Mørk; Staff, Anne Cathrine; Haasnoot, Geert W.; Westerink, Nienke; Claas, Frans H.J.; Rozemuller, Erik & Eikmans, Michael (2020). HLA-G whole gene amplification reveals linkage disequilibrium between the HLA-G 3′UTR and coding sequence. HLA.  ISSN 2059-2302.  96(2), s 179- 185 . doi: 10.1111/tan.13909
• Dyrkorn, Ole Aleksander; Staff, Anne Cathrine; Kulseng-Hanssen, Sigurd; Dimoski, Tomislav & Svenningsen, Rune (2020). The completeness and accuracy of the Norwegian Female Incontinence Registry. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  99, s 1618- 1625 . doi: 10.1111/aogs.13951
• Freitag, Nancy; Tirado-Gonzalez, Irene; Barrientos, Gabriela; Powell, Katie L.; Boehm-Sturm, Philipp; Koch, Stefan P.; Hecher, Kurt; Staff, Anne Cathrine; Arck, Petra Clara; Diemert, Anke & Blois, Sandra M. (2020). Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency. Cell Death & Disease.  ISSN 2041-4889.  11:560(7), s 1- 9 . doi: 10.1038/s41419-020-02791-5 Full text in Research Archive.
• Jacobsen, Daniel Pitz; Lekva, Tove; Moe, Kjartan; Fjeldstad, Heidi Elisabeth; Johnsen, Guro Mørk; Sugulle, Meryam & Staff, Anne Cathrine (2020). Pregnancy and postpartum levels of circulating maternal sHLA-G in preeclampsia. Journal of Reproductive Immunology.  ISSN 0165-0378.  143 . doi: 10.1016/j.jri.2020.103249 Full text in Research Archive.
• Lekva, Tove; Sugulle, Meryam; Moe, Kjartan; Redman, Christopher W.G.; Dechend, Ralf & Staff, Anne Cathrine (2020). Multiplex Analysis of Circulating Maternal Cardiovascular Biomarkers Comparing Preeclampsia Subtypes. Hypertension.  ISSN 0194-911X.  75(6), s 1513- 1522 . doi: 10.1161/HYPERTENSIONAHA.119.14580 Full text in Research Archive.
• Magi, Caroline-Aleksi Olsson; Backlund, Anders Bjerg; Carlsen, Karin C. Lødrup; Almqvist, Catarina; Carlsen, Kai-Håkon; Granum, Berit; Haugen, Guttorm; Hilde, Katarina; Carlsen, Oda Cecilie; Jonassen, Christine M; Rehbinder, Eva Maria; Sjøborg, Katrine Dønvold; Skjerven, Håvard Ove; Staff, Anne Cathrine; Vettukattil, Muhammad Riyas; Söderhäll, Cilla & Nordlund, Bjørn Kristian (2020). Allergic disease and risk of stress in pregnant women: a PreventADALL study. European Respiratory Journal Open Research (ERJ Open Research).  ISSN 2312-0541.  6(4) . doi: 10.1183/23120541.00175-2020 Full text in Research Archive.
• Mitlid-Mork, Birgitte; Bowe, Sophie; Gran, Jon Michael; Bolstad, Nils; Berg, Jens Petter; Redman, Christopher W.G.; Staff, Anne Cathrine & Sugulle, Meryam (2020). Maternal placental growth factor and soluble fms-like tyrosine kinase-1 reference ranges in post-term pregnancies: A prospective observational study. PLOS ONE.  ISSN 1932-6203.  15:e0240473(10), s 1- 14 . doi: 10.1371/journal.pone.0240473 Full text in Research Archive.
• Moe, Kjartan; Sugulle, Meryam; Dechend, Ralf; Angel, Kristin & Staff, Anne Cathrine (2020). Functional and structural vascular biomarkers in women 1 year after a hypertensive disorder of pregnancy. Pregnancy Hypertension.  ISSN 2210-7789.  21, s 23- 29 . doi: 10.1016/j.preghy.2020.04.008
• Nilsen, Morten; Schinagl, Carina Madelen; Angell, Inga Leena; Arntzen, Magnus Øverlie; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Haugen, Guttorm; Hagen, Live Heldal; Carlsen, Monica Hauger; Hedlin, Gunilla; Jonassen, Christine M; Nordlund, Bjørn; Rehbinder, Eva Maria; Skjerven, Håvard Ove; Snipen, Lars Gustav; Staff, Anne Cathrine; Vettukattil, Muhammad Riyas & Rudi, Knut (2020). Butyrate Levels in the Transition from an Infant-to an Adult-Like Gut Microbiota Correlate with Bacterial Networks Associated with Eubacterium Rectale and Ruminococcus Gnavus. Genes.  ISSN 2073-4425.  11(11) . doi: 10.3390/genes11111245 Full text in Research Archive.
• Nordhagen, Live Solveig; Kreyberg, Ina; Bains, Karen Eline Stensby; Carlsen, Kai-Håkon; Glavin, Kari; Skjerven, Håvard Ove; Småstuen, Milada Cvancarova; Hilde, Katarina; Nordlund, Björn; Vettukattil, Muhammad Riyas; Hedlin, Gunilla; Granum, Berit Brunstad; Jonassen, Christine M.; Gudmundsdóttir, Hrefna Katrín; Haugen, Guttorm; Rehbinder, Eva Maria; Söderhall, Cilla; Staff, Anne Cathrine & Carlsen, Karin C. Lødrup (2020). Maternal use of nicotine products and breastfeeding 3 months postpartum. Acta Paediatrica.  ISSN 0803-5253.  109(12), s 2594- 2603 . doi: 10.1111/apa.15299 Full text in Research Archive.
• Pay, Aase Serine Devold; Johansen, Katarina; Staff, Anne Cathrine; Laine, Katariina; Blix, Ellen & Økland, Inger (2020). Effects of external cephalic version for breech presentation at or near term in high-resource settings: A systematic review of randomized and non-randomized studies. European Journal of Midwifery.  ISSN 2585-2906.  4 . doi: 10.18332/ejm/128364
• Skjerven, Håvard Ove; Rehbinder, Eva Maria; Vettukattil, Muhammad Riyas; LeBlanc, Marissa Erin; Granum, Berit; Haugen, Guttorm; Hedlin, Gunilla; Landrø, Linn Aina Ysland; Marsland, Benjamin J.; Rudi, Knut; Sjøborg, Katrine Dønvold; Söderhäll, Cilla; Staff, Anne Cathrine; Carlsen, Kai-Håkon; Asarnoj, Anna; Bains, Karen Eline Stensby; Carlsen, Oda Cecilie; Endre, Kim Magnus Advocaat; Granlund, Peder Annæus; Hermansen, Johanne Uthus; Gudmundsdóttir, Hrefna Katrín; Hilde, Katarina; Håland, Geir; Kreyberg, Ina; Inge Christoffer, Olsen; Mägi, Caroline-Aleksi Olsson; Nordhagen, Live Solveig; Schinagl, Carina Madelen; Skrindo, Ingebjørg; Tedner, Sandra G.; Værnesbranden, Caren Magdalena Rydland; Wiik, Johanna; Jonassen, Christine M; Nordlund, Björn & Carlsen, Karin C. Lødrup (2020). Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial. The Lancet.  ISSN 0140-6736.  395(10228), s 951- 961 . doi: 10.1016/S0140-6736(19)32983-6 Full text in Research Archive.
• Snell, Kym I.E.; Allotey, John; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; Von Dadelszen, Peter; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony; Arenas Ramírez, Javier; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, Ahmet A.; Seed, Paul T.; Prefumo, Federico; da Silva Costa, Fabricio; Groen, Henk; Audibert, Francois; Masse, Jacques; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, Chie; Rumbold, Alice R.; Heinonen, Seppo; Askie, Lisa; Smits, Luc; Vinter, Christina; Magnus, Per; Eero, Kajantie; Villa, Pia M.; Jenum, Anne Karen; Andersen, Louise B.; Norman, Jane E.; Ohkuchi, Akihide; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala; Galindo, Alberto; Herraiz, Ignacio; Carbillon, Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Browne, Joyce L.; Moons, Karel G.M.; Riley, Richard D. & Thangaratinam, Shakila (2020). External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis. BMC Medicine.  ISSN 1741-7015.  18, s 1- 18 . doi: 10.1186/s12916-020-01766-9 Full text in Research Archive.
• Staff, Anne Cathrine & Dechend, Ralf (2020). Will Postnatal Renin-Angiotensin System Blockade Improve Long-Term Maternal Cardiovascular Health after Preeclampsia?. Hypertension.  ISSN 0194-911X.  76(6), s 1704- 1706 . doi: 10.1161/HYPERTENSIONAHA.120.16229
• Staff, Anne Cathrine; Fjeldstad, Heidi Elisabeth; Fosheim, Ingrid Knutsdotter; Moe, Kjartan; Turowski, Gitta Erika; Johnsen, Guro Mørk; Alnæs-Katjavivi, Patji & Sugulle, Meryam (2020). Failure of physiological transformation and spiral artery atherosis: their roles in preeclampsia. American Journal of Obstetrics and Gynecology.  ISSN 0002-9378.  s 1- 12 . doi: 10.1016/j.ajog.2020.09.026 Full text in Research Archive.
• Waldum, Åsa; Jacobsen, Anne Flem; Lukasse, Mirjam; Staff, Anne Cathrine; Falk, Ragnhild Sørum; Vangen, Siri & Sørbye, Ingvil (2020). The provision of epidural analgesia during labor according to maternal birthplace: a Norwegian register study. BMC Pregnancy and Childbirth.  ISSN 1471-2393.  20(321) . doi: 10.1186/s12884-020-03021-8 Full text in Research Archive. Show summary

  Background: The provision of epidural analgesia during labor is ideally a shared decision between the woman and her health care provider. However, immigrant characteristics such as maternal birthplace could affect decision-making and thus access to pain relief. We aimed to assess disparities in the provision of epidural analgesia in planned vaginal birth according to maternal region of birth. Methods: We performed a nation-wide register study of 842,496 live-born singleton deliveries in Norway between 2000 and 2015. Maternal birthplace was categorized according to the Global Burden of Disease framework. The provision of epidural analgesia was compared in regression models stratified by parity and mode of delivery. Results: Compared to native-born women, primiparous women from Latin America/Caribbean countries with an instrumental vaginal delivery were most likely to be provided epidural analgesia (OR 2.12, 95%CI 1.69–2.66), whilst multiparous women from Sub-Saharan Africa with a spontaneous vaginal delivery were least likely to be provided epidural analgesia (OR 0.42, 95% C 0.39–0.44). Longer residence time was associated with a higher likelihood of being provided analgesia, whereas effects of maternal education varied by Global Burden of Disease group. Conclusions: Disparities in the likelihood of being provided epidural analgesia were observed by maternal birthplace. Further studies are needed to consider whether the identified disparities represent women’s own preferences or if they are the result of heterogeneous access to analgesia during labor.

• Alnæs-Katjavivi, Patji; Roald, Borghild & Staff, Anne Cathrine (2019). Uteroplacental acute atherosis in preeclamptic pregnancies: Rates and clinical outcomes differ by tissue collection methods. Pregnancy Hypertension.  ISSN 2210-7789.  19, s 11- 17 . doi: 10.1016/j.preghy.2019.11.007 Full text in Research Archive.
• Brunetti, Marta; Holth, Arild; Panagopoulos, Ioannis; Staff, Anne Cathrine; Micci, Francesca & Davidson, Ben (2019). Expression and clinical role of the dipeptidyl peptidases DPP8 and DPP9 in ovarian carcinoma. Virchows Archiv.  ISSN 0945-6317.  474(2), s 177- 185 . doi: 10.1007/s00428-018-2487-x Full text in Research Archive.
• Cornish, Rosie; Staff, Anne Cathrine; Boyd, Andy; Lawlor, Debbie A.; Tretli, Steinar; Bradwin, Gary; McElrath, Thomas F.; Hyer, Marianne; Hoover, Robert N. & Troisi, Rebecca (2019). Maternal reproductive hormones and angiogenic factors in pregnancy and subsequent breast cancer risk. Cancer Causes and Control.  ISSN 0957-5243.  30(1), s 63- 74 . doi: 10.1007/s10552-018-1100-6
• Dyrkorn, Ole Aleksander; Staff, Anne Cathrine; Kulseng-Hanssen, Sigurd; Schiøtz, Hjalmar A. & Svenningsen, Rune (2019). Childbirth after mid-urethral sling surgery: effects on long-term success and complications. International Urogynecology Journal.  ISSN 0937-3462.  31(3), s 485- 492 . doi: 10.1007/s00192-019-04067-9 Show summary

  Introduction and hypothesis To evaluate long-term outcomes in women with one or more childbirths after mid-urethral sling (MUS) surgery and potential differences in outcomes based on mode of delivery. Methods A population-based cohort study using data from two national registries.Women registered with childbirth after MUS (case group) or without childbirth after MUS (control group), with equal follow-up time, underwent a structured telephone interview using a validated short-form urinary disease-specific questionnaire. Primary outcomes were current stress urinary incontinence (SUI) rate and change in cure rate. Secondary outcomes were effect of delivery mode, rates of repeat operations for SUI, complications, treatment satisfaction and urgency urinary incontinence rate. Childbirth as an independent risk factor for SUI recurrence was also evaluated. Results Seventy-two women with and 156 women without childbirth after MUS were included. Median follow-up time was 10 years for both groups. Subjective SUI cure rates were 82% (cases) and 75% (controls), respectively (p = 0.31). A significantly lower SUI cure rate was seen in the women with more than one childbirth after MUS (50% vs. 88% p = 0.006). No differences in primary or secondary outcomes were found between groups at follow-up, nor did mode of delivery affect outcomes. Childbirth after MUS was not an independent risk factor for subjective SUI recurrence (OR 0.8 CI 0.3–1.7). Conclusions No differences in outcomes were seen between groups at follow-up independently of delivery mode. However, having more than one delivery after MUS seems to impact the continence status.

• Endre, Kim Magnus Advocaat; Rehbinder, Eva Maria; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Gjersvik, Petter; Hedlin, Gunilla; Jonassen, Christine M; LeBlanc, Marissa Erin; Nordlund, Bjørn Kristian; Skjerven, Håvard Ove; Staff, Anne Cathrine; Söderhäll, Cilla; Vettukattil, Muhammad Riyas & Landrø, Linn Aina Ysland (2019). Maternal and paternal atopic dermatitis and risk of atopic dermatitis during early infancy in girls and boys. Journal of Allergy and Clinical Immunology: In Practice.  ISSN 2213-2198.  8(1), s 416- 418 . doi: 10.1016/j.jaip.2019.06.039 Full text in Research Archive.
• Fjeldstad, Heidi Elisabeth; Johnsen, Guro Mørk & Staff, Anne Cathrine (2019). Fetal microchimerism and implications for maternal health. Obstetric Medicine.  ISSN 1753-495X.  s 1- 8 . doi: 10.1177/1753495X19884484
• Fosheim, Ingrid K.; Alnæs-Katjavivi, Patji; Redman, Christopher; Roald, Borghild; Staff, Anne Cathrine & Størvold, Gro Leite (2019). Acute atherosis of decidua basalis; characterization of spiral arteries, endothelial status and activation. Placenta.  ISSN 0143-4004.  82, s 10- 16 . doi: 10.1016/j.placenta.2019.04.006 Full text in Research Archive.
• Gill, Navleen; Leng, Yaozhu; Romero, Roberto; Xu, Yi; Panaitescu, Bogdan; Miller, Derek; Arif, Afrah; Mumuni, Salma; Qureshi, Faisal; Hsu, Chaur-Dong; Hassan, Sonia S.; Staff, Anne Cathrine & Gómez-López, Nardhy (2019). The immunophenotype of decidual macrophages in acute atherosis. American journal of reproductive immunology.  ISSN 1046-7408.  81:e13098(4), s 1- 15 . doi: 10.1111/aji.13098
• Johnsen, Guro Mørk; Størvold, Gro Leite; Alnæs-Katjavivi, Patji; Roald, Borghild; Golic, Michaela; Dechend, Ralf; Redman, Christopher W.G. & Staff, Anne Cathrine (2019). Lymphocyte characterization of decidua basalis spiral arteries with acute atherosis in preeclamptic and normotensive pregnancies. Journal of Reproductive Immunology.  ISSN 0165-0378.  132, s 42- 48 . doi: 10.1016/j.jri.2019.03.003 Full text in Research Archive.
• Kreyberg, Ina; Bains, Karen Eline Stensby; Carlsen, Kai-Håkon; Granum, Berit; Gudmundsdóttir, Hrefna Katrín; Haugen, Guttorm; Hedlin, Gunilla; Hilde, Katarina; Jonassen, Christine M; Nordhagen, Live Solveig; Nordlund, Björn; Sjøborg, Katrine Dønvold; Skjerven, Håvard Ove; Staff, Anne Cathrine; Söderhäll, Cilla; Vettukattil, Muhammad Riyas & Carlsen, Karin C. Lødrup (2019). Stopping when knowing: use of snus and nicotine during pregnancy in Scandinavia. European Respiratory Journal Open Research (ERJ Open Research).  ISSN 2312-0541.  5(2) . doi: 10.1183/23120541.00197-2018 Full text in Research Archive.
• Kreyberg, Ina; Bains, Karen Eline Stensby; Carlsen, Kai-Håkon; Granum, Berit; Hilde, Katarina; Gudmundsdóttir, Hrefna Katrín; Haugen, Guttorm; Hedlin, Gunilla; Jonassen, Christine M; Nordhagen, Live Solveig; Nordlund, Björn; Sjøborg, Katrine Dønvold; Skjerven, Håvard Ove; Staff, Anne Cathrine; Söderhäll, Cilla; Rueegg, Corina Silvia; Vettukattil, Muhammad Riyas; Carlsen, Karin C. Lødrup & Despriee, Åshild (2019). Snus in pregnancy and infant birth size: a mother–child birth cohort study. European Respiratory Journal Open Research (ERJ Open Research).  ISSN 2312-0541.  5(4), s 1- 10 . doi: 10.1183/23120541.00255-2019 Full text in Research Archive.
• Moe, Kjartan; Sugulle, Meryam; Dechend, Ralf & Staff, Anne Cathrine (2019). Risk prediction of maternal cardiovascular disease one year after hypertensive pregnancy complications or gestational diabetes mellitus. European Journal of Preventive Cardiology (EJPC).  ISSN 2047-4873.  s 1- 11 . doi: 10.1177/2047487319879791
• Oversand, Sissel Hegdahl; Staff, Anne Cathrine; Volløyhaug, Ingrid & Svenningsen, Rune (2019). Impact of levator muscle avulsions on Manchester procedure outcomes in pelvic organ prolapse surgery. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  98(8), s 1046- 1054 . doi: 10.1111/aogs.13604 Show summary

  Introduction Levator ani muscle avulsions potentially increase recurrence after anterior colporrhaphies. We aimed at evaluating the impact of avulsions on anatomical and patient‐reported outcomes 1 year after the Manchester procedure for primary anterior compartment pelvic organ prolapse. Material and methods Prospective cohort study of 189 women undergoing the Manchester procedure between October 2014 and January 2017. Avulsions were diagnosed by transperineal ultrasound. Women with and without avulsions were compared for 1‐year postoperative outcomes; Pelvic Organ Prolapse Quantification measurements, subjective satisfaction (1—worse to 4—cured), failure (new prolapse treatment), response to validated questionnaires on pelvic floor distress and sexual function, and a composite outcome (subjectively cured and optimal anterior compartment outcome (stage 0‐I)). Optimal mid‐compartment outcome was defined as cervix ≥5 cm above the hymen. Factors potentially associated with poor anatomical outcomes (anterior compartment stage ≥II) or pelvic floor distress were analyzed using regression analyses. Results Fewer women with avulsions (present in 50.8%) obtained optimal mid‐compartment outcomes (88.2% vs 77.1%; P = 0.05). The groups were otherwise similar in terms of mid‐compartment reduction, anterior compartment results, failure rate, subjective satisfaction, pelvic floor/sexual symptoms, and combined optimal subjective and anatomical outcome. Only preoperative anterior compartment stage ≥III was associated with poor anatomical outcome (P < 0.01). A high preoperative symptom score was associated with a high postoperative symptom score (P < 0.001). Conclusions Although fewer women with avulsions obtained optimal mid‐compartment results, avulsions had no impact on other anatomical or symptomatic outcomes 1 year after the Manchester procedure for primary anterior compartment prolapse. Abbreviations LAM levator ani muscle PFDI‐20 Pelvic Floor Distress Inventory‐20 PISQ‐12 Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire POP pelvic organ prolapse POP‐Q Pelvic Organ Prolapse Quantification

• Rehbinder, Eva Maria; Endre, Kim Magnus Advocaat; Carlsen, Karin C. Lødrup; Asarnoj, Anna; Bains, Karen Eline Stensby; Berents, Teresa Løvold; Carlsen, Kai-Håkon; Gudmundsdóttir, Hrefna Katrín; Haugen, Guttorm; Hedlin, Gunilla; Kreyberg, Ina; Nordhagen, Live Solveig; Nordlund, Björn; Schinagl, Carina Madelen; Sandvik, Leiv; Skjerven, Håvard Ove; Söderhäll, Cilla; Staff, Anne Cathrine; Vettukattil, Muhammad Riyas; Værnesbranden, Caren Magdalena Rydland & Landrø, Linn Aina Ysland (2019). Predicting skin barrier dysfunction and atopic dermatitis in early infancy. Journal of Allergy and Clinical Immunology: In Practice.  ISSN 2213-2198.  s 1- 15 . doi: 10.1016/j.jaip.2019.09.014 Full text in Research Archive. Show summary

  Dry skin is associated with increased transepidermal water loss (TEWL), which has been found to precede atopic dermatitis (AD) in childhood. Objective We aimed to identify parental, prenatal, and perinatal predictive factors of dry skin, high TEWL, and AD at 3 months of age, and to determine if dry skin or high TEWL at 3 months can predict AD at 6 months. Methods From the Preventing Atopic Dermatitis and Allergies in children prospective birth cohort study, we included 1150 mother-child pairs. Dry skin, TEWL, and eczema were assessed at 3- and 6-month investigations. Eczema, used as a proxy for AD, was defined as the presence of eczematous lesions, excluding differential diagnoses to AD. High TEWL was defined as TEWL >90th percentile, equaling 11.3 g/m2/h. Potential predictive factors were recorded from electronic questionnaires at 18- and 34-week pregnancy and obstetric charts. Results Significant predictive factors (P < .05) for dry skin at 3 months were delivery >38 gestational weeks and paternal age >37 years; for high TEWL, male sex, birth during winter season, and maternal allergic disease; and for eczema, elective caesarean section, multiparity, and maternal allergic diseases. Dry skin without eczema at 3 months was predictive for eczema at 6 months (adjusted odds ratio: 1.92, 95% confidence interval: 1.21-3.05; P = .005), whereas high TEWL at 3 months was not. Conclusion In early infancy, distinct parental- and pregnancy-related factors were predictive for dry skin, high TEWL, and AD. Dry skin at 3 months of age was predictive for AD 3 months later.

• Schinagl, Carina Madelen; Rehbinder, Eva Maria; Carlsen, Karin C. Lødrup; Gudbrandsgard, Malén; Carlsen, Kai-Håkon; Haugen, Guttorm; Hedlin, Gunilla; Jonassen, Christine M; Sjøborg, Katrine Dønvold; Landrø, Linn Aina Ysland; Nordlund, Björn; Rudi, Knut; Skjerven, Håvard Ove; Söderhäll, Cilla; Staff, Anne Cathrine; Vettukattil, Muhammad Riyas & Carlsen, Monica Hauger (2019). Food and nutrient intake and adherence to dietary recommendations during pregnancy: A nordic mother?child population-based cohort. Food & Nutrition Research.  ISSN 1654-6628.  63:3676, s 1- 11 . doi: 10.29219/fnr.v63.3676 Full text in Research Archive.
• Scioscia, M; Dekker, GA; Chaouat, G; Dawonauth, L; Dechend, Ralf; Goldman-Wohl, D.; Gumilar, E; Karumanchi, SA; Kell, DB; Rademacher, TW; Robertson, S; Saito, S; Scherjon, Sicco; Staff, Anne Cathrine; Vatish, Manu & Robillard, PY (2019). A top priority in pre-eclampsia research: development of a reliable and inexpensive urinary screening test. The Lancet Global Health.  ISSN 2572-116X.  7(10), s e1312- e1313 . doi: 10.1016/S2214-109X(19)30319-5
• Sheiner, Eyal; Kapur, Anil; Retnakaran, Ravi; Hadar, Eran; Poon, Liona C.; McIntyre, H. David; Divakar, Hema; Staff, Anne Cathrine; Narula, Jagat; Kihara, Anne B. & Hod, Moshe (2019). FIGO (International Federation of Gynecology and Obstetrics) Postpregnancy initiative: Long-term maternal implications of pregnancy complications-follow-up considerations. International Journal of Gynecology & Obstetrics.  ISSN 0020-7292.  147, s 1- 31 . doi: 10.1002/ijgo.12926
• Staff, Anne Cathrine (2019). Long-term cardiovascular health after stopping pre-eclampsia. The Lancet.  ISSN 0140-6736.  394(10204), s 1120- 1121 . doi: 10.1016/S0140-6736(19)31993-2
• Staff, Anne Cathrine (2019). The two-stage placental model of preeclampsia: An update. Journal of Reproductive Immunology.  ISSN 0165-0378.  134-135, s 1- 10 . doi: 10.1016/j.jri.2019.07.004 Full text in Research Archive.
• Zeisler, Harald; Llurba, Elisa; Chantraine, Frédéric J.; Vatish, Manu; Staff, Anne Cathrine; Sennström, Maria; Olovsson, Matts; Brennecke, Shaun Patrick; Stepan, Holger; Allegranza, Deirdre; Schoedl, Maria; Grill, Sabine; Hund, Martin & Verlohren, Stefan (2019). Soluble fms-like tyrosine kinase-1 to placental growth factor ratio: ruling out pre-eclampsia for up to 4 weeks and value of retesting. Ultrasound in Obstetrics and Gynecology.  ISSN 0960-7692.  53, s 367- 375 . doi: 10.1002/uog.19178 Full text in Research Archive.
• Cabral-Marques, Otavio; Marques, Alexandre; Melvær, Giil Lasse; De Vito, Roberta; Rademacher, Judith; Günther, Jeannine; Lange, Tanja; Humrich, Jens; Klapa, Sebastian; Schinke, Susanne; Schimke, Lena; Marschner, Gabriele; Pitann, Silke; Adler, Sabine; Dechend, Ralf; Muller, Dominik N.; Braicu, Ioana; Sehouli, Jalid; Schulze-Forster, Kai; Trippel, Tobias; Scheibenbogen, Carmen; Staff, Anne Cathrine; Mertens, Peter; Löbel, Madlen; Mastroianni, Justin; Plattfaut, Corinna; Gieseler, Frank; Dragun, Duska; Engelhardt, Barbara Elizabeth; Fernandez-Cabezudo, Maria; Ochs, Hans D; Al-Ramadi, Basel K; Lamprecht, Peter; Mueller, Antje; Heidecke, Harald & Riemekasten, Gabriela (2018). GPCR-specific autoantibody signatures are associated with physiological and pathological immune homeostasis. Nature Communications.  ISSN 2041-1723.  9(5224) . doi: 10.1038/s41467-018-07598-9 Full text in Research Archive.
• Cerdeira, Ana Sofia; Agrawal, Swati; Staff, Anne Cathrine; Redman, Christopher W.G. & Vatish, Manu (2018). Angiogenic factors: potential to change clinical practice in pre-eclampsia?. BJOG: An International Journal of Obstetrics and Gynaecology.  ISSN 1470-0328.  125(11), s 1389- 1395 . doi: 10.1111/1471-0528.15042 Full text in Research Archive.
• Egeland, Grace M.; Skurtveit, Svetlana; Staff, Anne Cathrine; Eide, Geir Egil; Daltveit, Anne Kjersti; Klungsøyr, Kari; Trogstad, Lill; Magnus, Per; Brantsæter, Anne Lise & Haugen, Margaretha (2018). Pregnancy-related risk factors are associated with a significant burden of treated hypertension within 10 years of delivery: Findings from a population-based Norwegian Cohort. Journal of the American Heart Association (JAHA).  ISSN 2047-9980.  7(10) . doi: 10.1161/JAHA.117.008318 Full text in Research Archive.
• Fonnes, Tina; Trovik, Jone; Edqvist, Per-Henrik D.; Fasmer, Kristine Eldevik; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Bjørge, Line; Amant, Frédéric; Haldorsen, Ingfrid S.; Werner, Henrica Maria Johanna; Akslen, Lars A.; Tangen, Ingvild Løberg & Krakstad, Camilla (2018). Asparaginase-like protein 1 expression in curettage independently predicts lymph node metastasis in endometrial carcinoma: a multicentre study. BJOG: An International Journal of Obstetrics and Gynaecology.  ISSN 1470-0328.  125(13), s 1695- 1703 . doi: 10.1111/1471-0528.15403
• Halaas, Nathalie Bodd; Blennow, Kaj; Idland, Ane-Victoria; Wyller, Torgeir Bruun; Ræder, Johan; Frihagen, Frede Jon; Staff, Anne Cathrine; Zetterberg, Henrik & Watne, Leiv (2018). Neurofilament light in serum and cerebrospinal fluid of hip fracture patients with delirium. Dementia and Geriatric Cognitive Disorders.  ISSN 1420-8008.  46(5-6), s 346- 357 . doi: 10.1159/000494754 Full text in Research Archive.
• Johnsen, Guro Mørk; Størvold, Gro Leite; Drabbels, Jos J.M.; Haasnoot, Geert W.; Eikmans, Michael; Spruyt-Gerritse, Marijke J.; Alnæs-Katjavivi, Patji; Scherjon, Sicco A.; Redman, Christopher W.G.; Claas, Frans H.J. & Staff, Anne Cathrine (2018). The combination of maternal KIR-B and fetal HLA-C2 is associated with decidua basalis acute atherosis in pregnancies with preeclampsia. Journal of Reproductive Immunology.  ISSN 0165-0378.  129, s 23- 29 . doi: 10.1016/j.jri.2018.07.005
• Moe, Kjartan; Alnæs-Katjavivi, Patji; Størvold, Gro Leite; Sugulle, Meryam; Johnsen, Guro Mørk; Redman, Christopher W.G.; Dechend, Ralf & Staff, Anne Cathrine (2018). Classical cardiovascular risk markers in pregnancy and associations to uteroplacental acute atherosis. Hypertension.  ISSN 0194-911X.  72(3), s 695- 702 . doi: 10.1161/HYPERTENSIONAHA.118.10964 Full text in Research Archive.
• Oversand, Sissel Hegdahl; Staff, Anne Cathrine; Borstad, Ellen & Svenningsen, Rune (2018). The Manchester procedure: anatomical, subjective and sexual outcomes. International Urogynecology Journal.  ISSN 0937-3462.  29(8), s 1193- 1201 . doi: 10.1007/s00192-018-3622-6 Full text in Research Archive.
• Rehbinder, Eva Maria; Carlsen, Karin C. Lødrup; Staff, Anne Cathrine; Angell, Inga Leena; Landrø, Linn Aina Ysland; Hilde, Katarina; Gaustad, Peter & Rudi, Knut (2018). Is amniotic fluid of women with uncomplicated term pregnancies free of bacteria?. American Journal of Obstetrics and Gynecology.  ISSN 0002-9378.  219(3), s 289.e1- 289.e12 . doi: 10.1016/j.ajog.2018.05.028 Full text in Research Archive.
• Rieber-Mohn, Amalie; Sugulle, Meryam; Wallukat, Gerd; Alnæs-Katjavivi, Patji; Størvold, Gro Leite; Bolstad, Nils; Redman, Christopher W.G.; Dechend, Ralf & Staff, Anne Cathrine (2018). Auto-antibodies against the angiotensin II type I receptor in women with uteroplacental acute atherosis and preeclampsia at delivery and several years postpartum. Journal of Reproductive Immunology.  ISSN 0165-0378.  128, s 23- 29 . doi: 10.1016/j.jri.2018.05.008 Full text in Research Archive.
• Schmella, Mandy J.; Roberts, James M.; Conley, Yvette P.; Ren, Dianxu; Størvold, Gro Leite; Ingles, Sue A.; Wilson, Melissa L.; Staff, Anne Cathrine & Hubel, Carl A. (2018). Endoglin pathway genetic variation in preeclampsia: A validation study in Norwegian and Latina cohorts. Pregnancy Hypertension.  ISSN 2210-7789.  12, s 144- 149 . doi: 10.1016/j.preghy.2017.10.005 Full text in Research Archive.
• Sole, Kristina Baker; Staff, Anne Cathrine & Laine, Katariina (2018). The association of maternal country of birth and education with hypertensive disorders of pregnancy: A population-based study of 960 516 deliveries in Norway. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  97(10), s 1237- 1247 . doi: 10.1111/aogs.13393
• Svenningsen, Rune; Staff, Anne Cathrine; Langebrekke, Anton & Qvigstad, Erik (2018). Fertility outcome after cornual resection for interstitial pregnancies. Journal of minimally invasive gynecology.  ISSN 1553-4650.  s 1- 6 . doi: 10.1016/j.jmig.2018.08.017
• Barrientos, Gabriela; Pussetto, M.; Rose, Matthias; Staff, Anne Cathrine; Blois, Sandra Maria & Toblli, Jorge Eduardo (2017). Defective trophoblast invasion underlies fetal growth restriction and preeclampsia-like symptoms in the stroke-prone spontaneously hypertensive rat. Molecular human reproduction.  ISSN 1360-9947.  23(7), s 509- 519 . doi: 10.1093/molehr/gax024
• Leroy, Claire; Tobin, Kari Anne Risan; Basak, Sanjay; Staff, Anne Cathrine & Duttaroy, Asim K. (2017). Fatty acid-binding protein3 expression in BeWo cells, a human placental choriocarcinoma cell line. Prostaglandins, Leukotrienes and Essential Fatty Acids.  ISSN 0952-3278.  120, s 1- 7 . doi: 10.1016/j.plefa.2017.04.002
• Moe, Kjartan; Heidecke, Harald; Dechend, Ralf & Staff, Anne Cathrine (2017). Dysregulation of circulating autoantibodies against VEGF-A, VEGFR-1 and PlGF in preeclampsia ? A role in placental and vascular health?. Pregnancy Hypertension.  ISSN 2210-7789.  10, s 83- 89 . doi: 10.1016/j.preghy.2017.06.002 Full text in Research Archive.
• Njølstad, Tormund Salvesen; Werner, Henrica Maria Johanna; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Oddenes, Klaus; Bjørge, Line; Engh, Marie Ellström; Woie, Kathrine; Tjugum, Jostein; Lode, Margaret Sævik; Amant, Frédéric; Salvesen, Helga & Trovik, Jone (2017). Late-week surgical treatment of endometrial cancer is associated with worse long-term outcome: Results from a prospective, multicenter study. PLOS ONE.  ISSN 1932-6203.  12(8:e0182223), s 1- 12 . doi: 10.1371/journal.pone.0182223 Full text in Research Archive.
• Oversand, Sissel Hegdahl; Staff, Anne Cathrine; Sandvik, Leiv; Volløyhaug, Ingrid & Svenningsen, Rune (2017). Levator ani defects and the severity of symptoms in women with anterior compartment pelvic organ prolapse. International Urogynecology Journal.  ISSN 0937-3462.  29(1), s 63- 69 . doi: 10.1007/s00192-017-3390-8 Full text in Research Archive.
• Pay, Aase Serine Devold; Frøen, Frederik; Staff, Anne Cathrine; Jacobsson, Bo & Gjessing, Håkon K. (2017). Symfyse-fundus-mål – prediktiv verdi av ny referansekurve. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(10), s 717- 720 . doi: 10.4045/tidsskr.16.1022 Full text in Research Archive.
• Rimstad, Liv; SVENNINGSEN, RUNE; Schiøtz, Hjalmar A.; Moe, Kjartan; Staff, Anne Cathrine & Kulseng-Hanssen, Sigurd (2017). Sling mobilization in the management of urinary retention after mid-urethral sling surgery. Neurourology and Urodynamics.  ISSN 0733-2467.  36(4), s 1091- 1096 . doi: 10.1002/nau.23046 Full text in Research Archive. Show summary

  Objective To compare intermittent catheterization, sling mobilization, and sling transection for treatment of urinary retention after mid-urethral sling surgery. Methods Data registered in the Norwegian Female Incontinence Registry from 1998 to 2013 were analyzed in this cohort study to compare subjective and objective outcomes after intermittent catheterization, sling mobilization, and sling transection as management of postoperative urinary retention after mid urethral sling surgery. Subjective outcomes were degree of symptom bother and the percentage of women stating “very satisfied” at the postoperative follow-up. The objective outcome was leakage at a cough-jump pad stress test. Results Intervention due to urinary retention was performed in 585 of 18,772 women (3.1%). Women who had their sling mobilized or had intermittent catheterization, scored better on all postoperative outcomes than those who had their sling transected (P < 0.001). Sling transection was more often needed after intermittent catheterization than after mobilization (P = 0.023). No outcome differences were found between intermittent catheterization only and sling mobilization only. Intention to treat analysis showed that women who underwent sling mobilization as the primary procedure significantly more often had a negative stress test (P = 0.033) and were more often “very satisfied” with the treatment (P = 0.006) than those who were primarily catheterized. Conclusions Sling mobilization is a more successful treatment than intermittent catheterization or transection for urinary retention after mid-urethral sling surgery.

• Schalekamp-Timmermans, Sarah; Arends, Lidia R; Alsaker, Elin Hilde Roti; Chappell, Lucy; Hansson, Stefan; Harsem, Nina Kittelsen; Jälmby, Maya; Jeyabalan, Arundhathi; Laivuori, Hannele; Lawlor, Debbie A; Macdonald-Wallis, Corrie; Magnus, Per; Myers, Jenny; Olsen, Jørn; Poston, Lucilla; Redman, Christopher W; Staff, Anne Cathrine; Villa, Pia; Roberts, James M & Steegers, Eric A (2017). Fetal sex-specific differences in gestational age at delivery in pre-eclampsia: a meta-analysis. International Journal of Epidemiology.  ISSN 0300-5771.  46(2), s 632- 642 . doi: 10.1093/ije/dyw178 Full text in Research Archive.
• Sugulle, Meryam; Heidecke, Harald; Maschke, Ulrike; Herse, Florian; Danser, A.H. Jan; Mueller, Dominik; Staff, Anne Cathrine & Dechend, Ralf (2017). Soluble (pro)renin receptor in preeclampsia and diabetic pregnancies. Journal of the American Society of Hypertension : JASH.  ISSN 1933-1711.  11(10), s 644- 652 . doi: 10.1016/j.jash.2017.08.001
• Tangen, Ingvild Løberg; Kopperud, Reidun Kristin; Visser, Nicole C.M.; Staff, Anne Cathrine; Tingulstad, Solveig; Marcickiewicz, Janusz; Amant, Frédéric; Bjørge, Line; Pijnenborg, Johanna M.A.; Salvesen, Helga; Werner, Henrica Maria Johanna; Trovik, Jone & Krakstad, Camilla (2017). Expression of L1CAM in curettage or high L1CAM level in preoperative blood samples predicts lymph node metastases and poor outcome in endometrial cancer patients. British Journal of Cancer.  ISSN 0007-0920.  117(6), s 840- 847 . doi: 10.1038/bjc.2017.235 Full text in Research Archive.
• Zadora, Julianna; Singh, Manvendra; Herse, Florian; Przybyl, Lukasz; Haase, Nadine; Golic, Michaela; Yung, Hang Wa; Huppertz, Berthold; Cartwright, Judith E.; Whitley, Guy; Johnsen, Guro Mørk; Levi, Giovanni; Isbruch, Annette; Schulz, Herbert; Luft, Friedrich C; Muller, Dominik N.; Staff, Anne Cathrine; Hurst, Laurence D.; Dechend, Ralf & Izsvàk, Zsuzsanna (2017). Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Eearly Trophoblast Marker. Circulation.  ISSN 0009-7322.  136, s 1824- 1839 . doi: 10.1161/CIRCULATIONAHA.117.028110
• Alnæs-Katjavivi, Patji; Lyall, F; Roald, Borghild; Redman, CW & Staff, Anne Cathrine (2016). Acute atherosis in vacuum suction biopsies of decidua basalis: An evidence based research definition. Placenta.  ISSN 0143-4004.  37, s 26- 33 . doi: 10.1016/j.placenta.2015.10.020
• Bjerre, Anna Kristina; Tangeraas, Trine; Heidecke, Harald; Dragun, Duska; Dechend, Ralf & Staff, Anne Cathrine (2016). Angiotensin II type 1 receptor antibodies in childhood kidney transplantation. Pediatric Transplantation.  ISSN 1397-3142.  20(5), s 627- 632 . doi: 10.1111/petr.12728
• Burke, Órlaith; Benton, Samantha J.; Szafranski, Pawel; von Dadelszen, Peter; Buhimschi, S. Catalin; Cetin, Irene; Chappell, Lucy C.; Figueras, Francesc; Galindo, Alberto; Herraiz, Ignacio; Holzman, Claudia; Hubel, Carl; Knudsen, Ulla Lindbæk; Kronborg, Camilla; Laivuori, Hannele; Lapaire, Olav; McElrath, Thomas; Moertl, Manfred; Myers, Jenny; Ness, Roberta B.; Oliveira, Leandro; Olson, Gayle; Poston, Lucilla; Ris-Stalpers, Carrie; Roberts, James M.; Schalekamp-Timmermans, Sarah; Schlembach, Dietmar; Steegers, Eric A.P.; Stepan, Holger; Tsatsaris, Vassilis; van der Post, Joris A.; Verlohren, Stefan; Villa, Pia M.; Williams, David; Zeisler, Harald; Redman, Christopher W.G. & Staff, Anne Cathrine (2016). Extending the scope of pooled analyses of individual patient biomarker data from heterogeneous laboratory platforms and cohorts using merging algorithms. Pregnancy Hypertension.  ISSN 2210-7789.  6(1), s 53- 59 . doi: 10.1016/j.preghy.2015.12.002
• Falk, Roni T.; Staff, Anne Cathrine; Bradwin, Gary; Karumanchi, S. Ananth & Troisi, Rebecca (2016). A prospective study of angiogenic markers and postmenopausal breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Causes and Control.  ISSN 0957-5243.  27(8), s 1009- 1017 . doi: 10.1007/s10552-016-0779-5
• Fodstad, Kathrine; Staff, Anne Cathrine & Laine, Katariina (2016). Episiotomy preferences, indication, and classification - A survey among Nordic doctors. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  95(5), s 587- 595 . doi: 10.1111/aogs.12856
• Fodstad, Kathrine; Staff, Anne Cathrine & Laine, Katariina (2016). Sexual activity and dyspareunia the first year postpartum in relation to degree of perineal trauma. International Urogynecology Journal.  ISSN 0937-3462.  27(10), s 1513- 1523 . doi: 10.1007/s00192-016-3015-7
• Gervin, Kristina; Page, Christian; Aass, Hans Christian; Jansen, Michelle A; Fjeldstad, Heidi; Andreassen, Bettina Kulle; Duijts, Liesbeth; van Meurs, Joyce B; van Zelm, Menno C; Jaddoe, Vincent W; Nordeng, Hedvig Marie Egeland; Knudsen, Gun Peggy; Magnus, Per; Nystad, Wenche; Staff, Anne Cathrine; Felix, Janine F & Lyle, Robert (2016). Cell type specific DNA methylation in cord blood: a 450K-reference data set and cell count-based validation of estimated cell type composition. Epigenetics.  ISSN 1559-2294.  11(9), s 690- 698 . doi: 10.1080/15592294.2016.1214782
• Golic, Michaela; Haase, Nadine; Herse, Florian; Wehner, Anika; Vercruysse, Lisbeth; Pijnenborg, Robert; Balogh, Andras; Sæther, Per Christian; Dissen, Erik; Luft, Friedrich C.; Przybyl, Lukasz; Park, Joon-Keun; Alnæs-Katjavivi, Patji; Staff, Anne Cathrine; Verlohren, Stefan; Henrich, Wolfgang; Müller, Dominik N. & Dechend, Ralf (2016). Natural killer cell reduction and uteroplacental vasculopathy. Hypertension.  ISSN 0194-911X.  68(4), s 964- 973 . doi: 10.1161/HYPERTENSIONAHA.116.07800
• Hall, Roanna J.; Watne, Leiv Otto; Idland, Ane-Victoria; Ræder, Johan; Frihagen, Frede Jon; MacLullich, Alasdair M.J.; Staff, Anne Cathrine; Wyller, Torgeir Bruun & Fekkes, Durk (2016). Cerebrospinal fluid levels of neopterin are elevated in delirium after hip fracture. Journal of Neuroinflammation.  ISSN 1742-2094.  13:170 . doi: 10.1186/s12974-016-0636-1
• Holwerda, Kim M.; Weedon-Fekjær, Mina Susanne; Staff, Anne Cathrine; Nolte, Ilja M; van Goor, Harry; Lely, A Titia & Faas, Marijke M. (2016). The association of single nucleotide polymorphisms of the maternal cystathionine-β-synthase gene with early-onset preeclampsia. Pregnancy Hypertension.  ISSN 2210-7789.  6(1), s 60- 65 . doi: 10.1016/j.preghy.2015.12.001
• Hveem, Tarjei Sveinsgjerd; Njølstad, Tormund Salvesen; Nielsen, Birgitte; Syvertsen, Rolf Anders; Nesheim, John Arne; Kjæreng, Marna Lill; Kildal, Wanja; Pradhan, Manohar; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Haugland, Hans Kristian; Eraker, Runar; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik; Amant, Frédéric; Werner, Henrica Maria Johanna; Bjørge, Line; Albregtsen, Fritz; Liestøl, Knut; Salvesen, Helga; Trovik, Jone & Danielsen, Håvard Emil (2016). Changes in Chromatin Structure in Curettage Specimens Identifies High-Risk Patients in Endometrial Cancer. Cancer Epidemiology, Biomarkers and Prevention.  ISSN 1055-9965.  26(1), s 61- 67 . doi: 10.1158/1055-9965.EPI-16-0215
• Karppanen, Tiina; Kaartokallio, Tea; Klemetti, Miira M; Heinonen, Seppo; Kajantie, Eero; Kere, Juha; Kivinen, Katja; Pouta, Anneli; Staff, Anne Cathrine & Laivuori, Hannele (2016). An RGS2 3'UTR polymorphism is associated with preeclampsia in overweight women. BMC Genetics.  ISSN 1471-2156.  17(121) . doi: 10.1186/s12863-016-0428-8
• Pay, Aase Serine Devold; Frøen, Frederik; Staff, Anne Cathrine; Jacobsson, Bo & Gjessing, Håkon K. (2016). Prediction of small-for-gestational-age status by symphysis–fundus height: a registry-based population cohort study. BJOG: An International Journal of Obstetrics and Gynaecology.  ISSN 1470-0328.  123(7), s 1167- 1173 . doi: 10.1111/1471-0528.13727
• Przybyl, Lukasz; Haase, Nadine; Golic, Michaela; Rugor, Julianna; Solano, Maria Emilia; Arck, Petra Clara; Gauster, Martin; Huppertz, Berthold; Emontzpohl, Christoph; Stoppe, Christian; Bernhagen, Jürgen; Leng, Lin; Bucala, Richard; Schulz, Herbert; Heuser, Arnd; Weedon-Fekjær, Mina Susanne; Johnsen, Guro Mørk; Peetz, Dirk; Luft, Friedrich C.; Staff, Anne Cathrine; Müller, Dominik N.; Dechend, Ralf & Herse, Florian (2016). CD74-downregulation of placental macrophage-trophoblastic interactions in preeclampsia. Circulation Research.  ISSN 0009-7330.  119(1), s 55- 68 . doi: 10.1161/CIRCRESAHA.116.308304
• Sequeira de Sousa, Ana Rita; Staff, Anne Cathrine; Johnsen, Guro Mørk; Weedon-Fekjær, Mina Susanne & Størvold, Gro Leite (2016). Evaluation of four commonly used normalizer genes for the study of decidual gene expression. Placenta.  ISSN 0143-4004.  43, s 9- 12 . doi: 10.1016/j.placenta.2016.04.009
• Staff, Anne Cathrine; Redman, Chris W.G.; Williams, D; Leeson, P; Moe, Kjartan; Thilaganathan, Baskaran; Magnus, Per; Steegers, E; Tsigas, E; Ness, RB; Myatt, L.; Poston, Lucilla & Roberts, J. (2016). Pregnancy and Long-Term Maternal Cardiovascular Health: Progress Through Harmonization of Research Cohorts and Biobanks. Hypertension.  ISSN 0194-911X.  67(2), s 251- 260 . doi: 10.1161/HYPERTENSIONAHA.115.06357
• Tekpli, Xavier; Urbanucci, Alfonso; Hashim, Adnan; Vågbø, Cathrine Broberg; Lyle, Robert; Kringen, Marianne K.; Staff, Anne Cathrine; Dybedal, Ingunn; Mills, Ian Geoffrey; Klungland, Arne & Staerk, Judith (2016). Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells. Epigenetics & Chromatin.  ISSN 1756-8935.  9 . doi: 10.1186/s13072-016-0070-8 Full text in Research Archive.
• Yung, Hong-wa; Alnæs-Katjavivi, Patji; Jones, Carolyn J.P.; El-Bacha, Tatiana; Golic, Michaela; Staff, Anne Cathrine & Burton, Graham J. (2016). Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants. Diabetologia.  ISSN 0012-186X.  59(10), s 2240- 2250 . doi: 10.1007/s00125-016-4040-2
• Zeisler, Harald; Llurba, Elisa; Chantraine, Frederic; Vatish, Manu; Staff, Anne Cathrine; Sennström, Maria; Olovsson, Matts; Brennecke, Shaun P.; Stepan, Holger; Allegranza, Deirdre; Dilba, Peter; Schoedl, Maria; Hund, Martin & Verlohren, Stefan (2016). Predictive value of the sFlt-1:PlGF ratio in women with suspected preeclampsia. New England Journal of Medicine.  ISSN 0028-4793.  374(1), s 13- 22 . doi: 10.1056/NEJMoa1414838
• Zeisler, Harald; Llurba, Elisa; Chantraine, Frederic; Vatish, Manu; Staff, Anne Cathrine; Sennström, Maria; Olovsson, Matts; Brennecke, Shaun P.; Stepan, Holger; Allegranza, Deirdre; Dinkel, A.; Schoedl, Maria; Dilba, Peter; Hund, Martin & Verlohren, Stefan (2016). Soluble fms-Like Tyrosine Kinase-1-to-Placental Growth Factor Ratio and Time to Delivery in Women With Suspected Preeclampsia.. Obstetrics and Gynecology.  ISSN 0029-7844.  128, s 261- 269 . doi: 10.1097/AOG.0000000000001525
• Barbaux, S.; Erwich, J. J. H. M.; Favaron, P. O.; Gil, S.; Gallot, D.; Golos, T. G.; Gonzalez-Bulnes, A.; Guibourdenche, J.; Heazell, A. E. P.; Jansson, T.; Laprévote, O.; Lewis, R. M.; Miller, R. K.; Monk, D.; Novakovic, B.; Oudejans, C.; Parast, M.; Peugnet, P.; Pfarrer, C.; Pinar, H.; Roberts, C. T.; Robinson, W.; Saffery, R; Salomon, C.; Sexton, A.; Staff, Anne Cathrine; Suter, M.; Tarrade, A.; Wallace, J.; Vaillancourt, C.; Vaiman, D.; Worton, S. A. & Lash, G.E. (2015). IFPA meeting 2014 workshop report: Animal models to study pregnancy pathologies; new approaches to study human placental exposure to xenobiotics; biomarkers of pregnancy pathologies; placental genetics and epigenetics; the placenta and stillbirth and fetal growth restriction. Placenta.  ISSN 0143-4004.  36(1), s S5- S10 . doi: 10.1016/j.placenta.2015.01.196
• Blois, Sandra M.; Dechend, Ralf; Barrientos, Gabriela & Staff, Anne Cathrine (2015). A potential pathophysiological role for galectins and the renin-angiotensin system in preeclampsia. Cellular and Molecular Life Sciences (CMLS).  ISSN 1420-682X.  72(1), s 39- 50 . doi: 10.1007/s00018-014-1713-1
• Burke, O; Benton, S; Szafranski, P; von Dadelscen, P; Buhimschi, C; Cetin, I; Chapell, L; Figueras, F.; Galindo, A; Herraiz, I; Holzman, Claudia; Hubel, Carl A; Knudsen, U; Kronborg, Christian; Laivuori, H; McElrath, T; Moerti, M; Meyers, JM; Ness, RB; Oliviera, L; Olson, G.; Poston, Lucilla; Ris-Stalpers, C; Roberts, JM; Schistermann, E; Steegers, E; Stepan, H; Lapaire, Olav; Schlemback, D; Timmermanns, S; Tsatsaris, V; van der Post, JA; Verlohren, S; Villa, PM; Williams, D; Zeisler, H; Zhang, C; Redman, Chris W.G. & Staff, Anne Cathrine (2015). [94-OR]: Extending the scope of individual patient data meta-analyses: Merging algorithms for biomarker measurements from heterogeneous laboratory platforms. The CoLAB Preeclampsia angiogenic factor study. Pregnancy Hypertension.  ISSN 2210-7789.  5(1), s 50- 51 . doi: 10.1016/j.preghy.2014.10.098 Full text in Research Archive.
• Gjersøe, Lene; Lykke, Jacob Alexander & Staff, Anne Cathrine (2015). Angiogenic biomarkers in pregnancy: Defining maternal and fetal health. Acta Obstetricia et Gynecologica Scandinavica.  ISSN 0001-6349.  94(8), s 820- 832 . doi: 10.1111/aogs.12629 Full text in Research Archive. Show summary

  We review diagnostic and predictive roles of the angiogenic proteins placental growth factor, soluble fms-like tyrosine kinase 1 and soluble endoglin in preeclampsia, and their association with future cardiovascular disease, diabetes and breast cancer. Specific patterns of these proteins represent preeclamptic prediction markers and combined with maternal and clinical characteristics, the predictive values increase. Women experiencing preeclampsia have increased risks of developing cardiovascular diseases and diabetes, and a decreased risk of breast cancer. High placental growth factor concentrations have in elderly patients been shown to predict cardiovascular events. Diabetes is also a risk factor for future cardiovascular disease. Diabetic vascular complications are associated with increased soluble endoglin concentrations, and vascular endothelial growth factor concentrations are correlated to HbA1c and fasting glucose. Thus dysregulation in angiogenic proteins may link preeclampsia and cardiovascular diseases, targeting women who could in future benefit from prophylactic programs to possibly prevent, delay or reduce cardiovascular disease.

• Njølstad, Tormund Salvesen; Trovik, Jone; Hveem, Tarjei Sveinsgjerd; Kjæreng, Marna Lill; Kildal, Wanja; Pradhan, Manohar; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Haugland, Hans Kristian; Eraker, Runar; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik; Amant, Frédéric; Werner, Henrica Maria Johanna; Salvesen, Helga & Danielsen, Håvard Emil (2015). DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer. British Journal of Cancer.  ISSN 0007-0920.  112, s 1656- 1664 . doi: 10.1038/bjc.2015.123 Full text in Research Archive.
• Nymoen, Dag Andre; Falkenthal, Thea Eline Hetland; Holth, Arild; Ow, Ghim Siong; Ivshina, Anna V.; Tropé, Claes Gøran; Kuznetsov, Vladimir; Staff, Anne Cathrine & Davidson, Ben (2015). Expression and clinical role of chemoresponse-associated genes in ovarian serous carcinoma. Gynecologic Oncology.  ISSN 0090-8258.  139(1), s 30- 39 . doi: 10.1016/j.ygyno.2015.07.107

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• Staff, Anne Cathrine (2019). Why do circulating biomarkers predict early-onset preeclampsia, and can they also predict future maternal cardiovascular health?. Hypertension.  ISSN 0194-911X.  74(5), s 1084- 1086 . doi: 10.1161/HYPERTENSIONAHA.119.13722
• Carlsen, Karin C. Lødrup; Rehbinder, Eva Maria; Skjerven, Håvard Ove; Carlsen, Monica Hauger; Fatnes, Thea Aspelund; Fugeli, Pål; Granum, Berit; Haugen, Guttorm; Hedlin, Gunilla; Jonassen, Christine M; Landrø, Linn Aina Ysland; Lunde, Jon; Marsland, Benjamin J.; Nordlund, Björn; Rudi, Knut; Sjøborg, Katrine Dønvold; Söderhäll, Cilla; Staff, Anne Cathrine; Vettukattil, Muhammad Riyas & Carlsen, Kai-Håkon (2018). Preventing Atopic Dermatitis and ALLergies in Children-the PreventADALL study.. Allergy. European Journal of Allergy and Clinical Immunology.  ISSN 0105-4538.  73(10), s 2063- 2070 . doi: 10.1111/all.13468
• Alnæs-Katjavivi, Patji; Lyall, Fiona; Roald, Borghild; Redman, Christopher W.G. & Staff, Anne Cathrine (2017). Corrigendum to "Acute atherosis in vacuum suction biopsies of decidua basalis: An evidence based research definition" [Placenta 37C (2016) 26-33] (S0143400415300801) (10.1016/j.placenta.2015.10.020). Placenta.  ISSN 0143-4004.  52, s 114- 115 . doi: 10.1016/j.placenta.2017.03.002
• Staff, Anne Cathrine & Redman, Christopher (2017). Staff and Redman response to placenta letter by Brosens. Placenta.  ISSN 0143-4004.  58, s 133- 133 . doi: 10.1016/j.placenta.2017.05.014
• Johnsen, Guro Mørk; Størvold, Gro Leite; Drabbles, Jos J.M.; Haasnoot, Geert W.; Eikmans, Michael; Alnæs-Katjavivi, Patji; Scherjon, Sicco; Redman, Christopher W.G.; Claas, Frans H.J. & Staff, Anne Cathrine (2016). Maternal KIR-B haplotype in combination with fetal HLA-C2 is associated with pregnancy acute atherosis in the decidua basalis. Journal of Reproductive Immunology.  ISSN 0165-0378.  115, s 63- 64
• Johnsen, Guro Mørk; Weedon-Fekjær, Mina Susanne; Tobin, Kari Anne Risan; Staff, Anne Cathrine & Duttaroy, Asim K. (2016). Erratum: Corrigendum to “Long-chain polyunsaturated fatty acids stimulate cellular fatty acid uptake in human placental choriocarcinoma (Bewo) cells” (Placenta (2009) 30(12) (1037–1044) (S0143400409003208) (10.1016/j.placenta.2009.10.004)). Placenta.  ISSN 0143-4004.  47, s 131- 131 . doi: 10.1016/j.placenta.2016.09.002
• Redman, Christopher W.G. & Staff, Anne Cathrine (2016). Reply. American Journal of Obstetrics and Gynecology.  ISSN 0002-9378.  214(5), s 669- 669 . doi: 10.1016/j.ajog.2016.01.006
• Staff, Anne Cathrine; Alnæs-Katjavivi, Patji & Redman, Christopher W.G. (2016). Decidual acute atherosis and "halo of hyalinization" - A Response to "The aetiology of narrowed uterine arterioles in obstetric and gynaecological syndromes" by Dr. M.J Quinn". Placenta.  ISSN 0143-4004.  44, s 115- 115 . doi: 10.1016/j.placenta.2016.03.005
• Staff, Anne Cathrine; Andersgaard, Alice Beathe; Henriksen, Tore; Langesæter, Eldrid; Magnussen, Elisabeth; Michelsen, Trond Melbye; Thomsen, Liv Cecilie Vestrheim & Øian, Pål (2016). Chapter 28 Hypertensive disorders of pregnancy and eclampsia. European Journal of Obstetrics, Gynecology, and Reproductive Biology.  ISSN 0301-2115.  201, s 171- 178 . doi: 10.1016/j.ejogrb.2016.04.001
• Johnsen, Guro Mørk; Sheng, Vincent O.Y.; Tasken, Kjetil; Staff, Anne Cathrine & Malmberg, Karl-Johan (2015). Killer immunoglobulin-like receptors (KIRS) on 3rd trimester decidual natural killer cells. Journal of Reproductive Immunology.  ISSN 0165-0378.  111, s 11 . doi: 10.1016/j.jri.2015.06.073

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