Jan Terje Andersen
Professor
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Department of Pharmacology
Norwegian version of this page
Phone
+47 22857275
Username
Visiting address
Sognsvannsveien 20
Rikshospitalet
0372 Oslo
Postal address
Postboks 1057 Blindern
0316 Oslo
Publications
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Benjakul, Sopisa; Anthi, Aina Karen; Kolderup, Heidi Anette; Vaysburd, Marina; Lode, Heidrun Elisabeth & Mallery, D [Show all 20 contributors for this article] (2023). A pan-SARS-CoV-2-specific soluble angiotensin-converting enzyme 2-albumin fusion engineered for enhanced plasma half-life and needle-free mucosal delivery. PNAS Nexus. ISSN 2752-6542. 2(12), p. 1–15. doi: 10.1093/pnasnexus/pgad403. Full text in Research Archive
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Tulika, Tulika; Pedersen, Rasmus W.; Rimbault, Charlotte; Ahmadi, Shirin; Rivera-de-Torre, Esperanza & Fernández-Quintero, Monica L. [Show all 14 contributors for this article] (2023). Phage display assisted discovery of a pH-dependent anti-α-cobratoxin antibody from a natural variable domain library. Protein Science. ISSN 0961-8368. 32(12), p. 1–17. doi: 10.1002/pro.4821. Full text in Research Archive
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Jørstad, Øystein Kalsnes; Foss, Stian; gjølberg, torleif; mester, simone; Nyquist-Andersen, Mari & Sivertsen, Magne S. [Show all 10 contributors for this article] (2023). Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties. International Journal of Retina and Vitreous (IJRV). ISSN 2056-9920. 9(1). doi: 10.1186/s40942-023-00507-3. Full text in Research Archive
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Lustig, Marta; Chan, Chilam; Jansen, J. H. Marco; Bräutigam, Maria; Kölling, Max A. & Gehlert, Carina Lynn [Show all 16 contributors for this article] (2023). Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells. Frontiers in Immunology. ISSN 1664-3224. 14, p. 1–15. doi: 10.3389/fimmu.2023.1178817. Full text in Research Archive
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Mukadam, Aamir S.; Miller, Lauren V.C.; Smith, Annabel E.; Vaysburd, Marina; Sakya, Siri Aastedatter & Sanford, Sophie [Show all 24 contributors for this article] (2023). Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models. Science. ISSN 0036-8075. 379(6639), p. 1336–1341. doi: 10.1126/science.abn1366.
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gjølberg, torleif; Wik, Jonas Aakre; Johannessen, Hanna; Krüger, Stig; Bassi, Nicola & Christopoulos, Panagiotis [Show all 15 contributors for this article] (2023). Antibody blockade of Jagged1 attenuates choroidal neovascularization. Nature Communications. ISSN 2041-1723. 14(1). doi: 10.1038/s41467-023-38563-w. Full text in Research Archive
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Fernández-Quintero, Monica L.; Ljungars, Anne; Waibl, Franz; Greiff, Victor; Andersen, Jan Terje & Gjølberg, Torleif [Show all 16 contributors for this article] (2023). Assessing developability early in the discovery process for novel biologics. mAbs. ISSN 1942-0862. 15:2171248(1), p. 1–19. doi: 10.1080/19420862.2023.2171248. Full text in Research Archive
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gjølberg, torleif; Lode, Heidrun Elisabeth; Melo, Gustavo B.; mester, simone; Probst, Christine & Sivertsen, Magne S. [Show all 9 contributors for this article] (2022). A Silicone Oil-Free Syringe Tailored for Intravitreal Injection of Biologics. Frontiers in Ophthalmology. ISSN 2674-0826. 2. doi: 10.3389/fopht.2022.882013.
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Tran, Trung; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa & Kolderup, Heidi Anette [Show all 40 contributors for this article] (2022). Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants. npj Vaccines. ISSN 2059-0105. 7(1). doi: 10.1038/s41541-022-00586-7. Full text in Research Archive
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Wade, Jack; Rimbault, Charlotte; Ali, Hanif; Ledsgaard, Line; Rivera-De-Torre, Esperanza & Abou Hachem, Maher [Show all 13 contributors for this article] (2022). Generation of Multivalent Nanobody-Based Proteins with Improved Neutralization of Long α-Neurotoxins from Elapid Snakes. Bioconjugate chemistry. ISSN 1043-1802. 33(8), p. 1494–1504. doi: 10.1021/acs.bioconjchem.2c00220. Full text in Research Archive
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Sand, Kine Marita Knudsen; Gruber, Michael M.; Sandlie, Inger; Mathiesen, Line; Andersen, Jan Terje & Wadsack, Christian (2022). Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer. Placenta. ISSN 0143-4004. 127, p. 77–87. doi: 10.1016/j.placenta.2022.07.019. Full text in Research Archive
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Mørtberg, Trude Victoria; Zhi, Huiying; Vidarsson, Gestur; Foss, Stian; Lissenberg-Thunnissen, Suzanne & Wuhrer, Manfred [Show all 12 contributors for this article] (2022). Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody. ImmunoHorizons. ISSN 2573-7732. 6(1), p. 90–103. doi: 10.4049/immunohorizons.2100097. Full text in Research Archive
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Søraas, Arne Vasli; Grødeland, Gunnveig; Granerud, Beathe Kiland; Ueland, Thor; Lind, Andreas & Fevang, Børre [Show all 32 contributors for this article] (2022). Breakthrough infections with the omicron and delta variants of SARS-CoV-2 result in similar re-activation of vaccine-induced immunity. Frontiers in Immunology. ISSN 1664-3224. 13:964525, p. 1–12. doi: 10.3389/fimmu.2022.964525. Full text in Research Archive Show summary
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Foss, Stian; Jonsson, Alexandra; Bottermann, Maria; Watkinson, Ruth; Lode, Heidrun Elisabeth & McAdam, Martin Berner [Show all 10 contributors for this article] (2022). Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge. Science immunology. ISSN 2470-9468. 7(70). doi: 10.1126/sciimmunol.abj1640.
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Ward, E. Sally; Gelinas, Deborah; Dreesen, Erwin; Van Santbergen, Jolien; Andersen, Jan Terje & Silvestri, Nicholas J. [Show all 13 contributors for this article] (2022). Clinical Significance of Serum Albumin and Implications of FcRn Inhibitor Treatment in IgG-Mediated Autoimmune Disorders. Frontiers in Immunology. ISSN 1664-3224. 13:892534, p. 1–13. doi: 10.3389/fimmu.2022.892534. Full text in Research Archive
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Tollefsrud Gjølberg, Torleif; Frick, Rahel; Mester, Simone; Foss, Stian; Grevys, Algirdas & Høydahl, Lene Støkken [Show all 11 contributors for this article] (2022). Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life. Communications Biology. ISSN 2399-3642. 5(1), p. 1–17. doi: 10.1038/s42003-022-03787-x. Full text in Research Archive
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Akbar, Rahmad; Bashour, Habib; Rawat, Puneet; Robert, Philippe Paul Auguste; Smorodina, Eva & Cotet, Tudor-Stefan [Show all 15 contributors for this article] (2022). Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies. mAbs. ISSN 1942-0862. 14:e2008790(1), p. 1–35. doi: 10.1080/19420862.2021.2008790. Full text in Research Archive
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Zakrzewicz, Anna; Würth, Celina; Beckert, Benedikt; Feldhoff, Simon; Vanderheyden, Katrien & Foss, Stian [Show all 11 contributors for this article] (2022). Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? Cells. ISSN 2073-4409. 11:942(6), p. 1–23. doi: 10.3390/cells11060942. Full text in Research Archive
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Akbar, Rahmad; Robert, Philippe Paul Auguste; Weber, Cédric R.; Widrich, Michael; Frank, Robert & Pavlovic, Milena [Show all 19 contributors for this article] (2022). In silico proof of principle of machine learning-based antibody design at unconstrained scale. mAbs. ISSN 1942-0862. 14:e2031482(1), p. 1–18. doi: 10.1080/19420862.2022.2031482. Full text in Research Archive
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Grevys, Algirdas; Frick, Rahel; Mester, Simone; Flem-Karlsen, Karine; Nilsen, Jeannette & Foss, Stian [Show all 13 contributors for this article] (2022). Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life. iScience. ISSN 2589-0042. 25:103746(2), p. 1–22. doi: 10.1016/j.isci.2022.103746. Full text in Research Archive
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Sivertsen, Magne S.; Lode, Heidrun Elisabeth; Tollefsrud Gjølberg, Torleif; Petrovski, Goran; Andersen, Jan Terje & Jørstad, Øystein Kalsnes [Show all 7 contributors for this article] (2021). Cluster of symptomatic silicone oil droplets following intravitreal injections: A 1-year observational study. BMJ Open Ophthalmology. ISSN 2397-3269. 6:e000764(1), p. 1–5. doi: 10.1136/bmjophth-2021-000764. Full text in Research Archive
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Azevedo, Cláudia; Pinto, Soraia; Benjakul, Sopisa; Nilsen, Jeannette; Santos, Helder A. & Traverso, Giovanni [Show all 8 contributors for this article] (2021). Prevention of diabetes-associated fibrosis: Strategies in FcRn-targeted nanosystems for oral drug delivery. Advanced Drug Delivery Reviews. ISSN 0169-409X. 175. doi: 10.1016/j.addr.2021.04.016. Full text in Research Archive
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Christopoulos, Panagiotis; Gjølberg, Torleif Tollefsrud; Krüger, Stig; Haraldsen, Guttorm; Andersen, Jan Terje & Sundlisæter, Eirik (2021). Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases. Frontiers in Immunology. ISSN 1664-3224. 12:668207, p. 1–22. doi: 10.3389/fimmu.2021.668207. Full text in Research Archive
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Azevedo, Cláudia; Andersen, Jan Terje; Traverso, Giovanni & Sarmento, Bruno (2021). The potential of porcine ex vivo platform for intestinal permeability screening of FcRn-targeted drugs. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 162, p. 99–104. doi: 10.1016/j.ejpb.2021.03.009.
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König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, Trung; Schikora-Rustad, Stine & Vaage, Eline Benno [Show all 22 contributors for this article] (2021). Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations. Journal of Neurology, Neurosurgery and Psychiatry. ISSN 0022-3050. doi: 10.1136/jnnp-2021-327612. Full text in Research Archive
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Tunheim, Gro; Rø, Gunnar Øyvind Isaksson; Tran, Trung; Kran, Anne-Marte Bakken; Andersen, Jan Terje & Vaage, Eline Benno [Show all 10 contributors for this article] (2021). Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic. Influenza and Other Respiratory Viruses. ISSN 1750-2640. 16(2), p. 204–212. doi: 10.1111/irv.12932. Full text in Research Archive
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Merten, Hannes; Brandl, Fabian; Zimmermann, Martina; Schaefer, Jonas V.; Irpinio, Linda & Sand, Kine M.K. [Show all 10 contributors for this article] (2021). Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 167, p. 104–113. doi: 10.1016/j.ejpb.2021.07.011. Full text in Research Archive
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Mester, Simone; Evers, Mitchell; Meyer, Saskia; Nilsen, Jeannette; Greiff, Victor & Sandlie, Inger [Show all 8 contributors for this article] (2021). Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo. mAbs. ISSN 1942-0862. 13:1893888(1), p. 1–14. doi: 10.1080/19420862.2021.1893888. Full text in Research Archive
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Mandrup, Ole A.; Ong, Sui Ching; Lykkemark, Simon; Dinesen, Anders; Rudnik-Jansen, Imke & Dagnæs-Hansen, Niels Frederik [Show all 9 contributors for this article] (2021). Programmable half-life and anti-tumour effects of bispecific T-cell engager-albumin fusions with tuned FcRn affinity. Communications Biology. ISSN 2399-3642. 4:310(1), p. 1–11. doi: 10.1038/s42003-021-01790-2. Full text in Research Archive
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Lombardi, Silvia; Hovden Aaen, Kristin; Nilsen, Jeannette; Ferrarese, Mattia; Tollefsrud Gjølberg, Torleif & Bernardi, Francesco [Show all 9 contributors for this article] (2021). Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity. British Journal of Haematology. ISSN 0007-1048. 194(2), p. 453–462. doi: 10.1111/bjh.17559. Full text in Research Archive
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Barratt-Due, Andreas; Olsen, Inge Christoffer; Nezvalova-Henriksen, Katerina; Kåsine, Trine; Lund-Johansen, Fridtjof & Hoel, Hedda Benedicte [Show all 43 contributors for this article] (2021). Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial. Annals of Internal Medicine. ISSN 0003-4819. 174(9), p. 1261–1269. doi: 10.7326/M21-0653. Full text in Research Archive Show summary
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Høydahl, Lene; Frigstad, Terje; Rasmussen, Ingunn B; Øynebråten, Inger; Schjetne, Karoline W & Andersen, Jan Terje [Show all 10 contributors for this article] (2021). Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses. Vaccine. ISSN 0264-410X. 39(11), p. 1583–1592. doi: 10.1016/j.vaccine.2021.02.012. Full text in Research Archive
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Caddy, Sarah L.; Vaysburd, Marina; Papa, Guido; Wing, Mark; O'Connell, Kevin & Stoycheva, Diana [Show all 10 contributors for this article] (2020). Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity. EMBO Journal. ISSN 0261-4189. 40:e106228(5), p. 1–9. doi: 10.15252/embj.2020106228. Full text in Research Archive
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Schrottmaier, Waltraud C.; Salzmann, Manuel; Badrnya, Sigrun; Mussbacher, Marion; Kral-Pointer, Julia B. & Morava, Susanne [Show all 17 contributors for this article] (2020). Platelets mediate serological memory to neutralize viruses in vitro and in vivo. Blood Advances. ISSN 2473-9529. 4(16), p. 3971–3976. doi: 10.1182/bloodadvances.2020001786. Full text in Research Archive
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Hovden Aaen, Kristin; Anthi, Aina Karen; Sandlie, Inger; Nilsen, Jeannette; Mester, Simone & Andersen, Jan Terje (2020). The neonatal Fc receptor in mucosal immune regulation. Scandinavian Journal of Immunology. ISSN 0300-9475. doi: 10.1111/sji.13017.
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Nilsen, Jeannette; Trabjerg, Esben; Grevys, Algirdas; Azevedo, Claudia; Brennan, Stephen O. & Stensland, Maria [Show all 14 contributors for this article] (2020). An intact C-terminal end of albumin is required for its long half-life in humans. Communications Biology. ISSN 2399-3642. 3(1). doi: 10.1038/s42003-020-0903-7. Full text in Research Archive
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Hubbard, Jonathan J.; Pyzik, Michal; Rath, Timo; Kozicky, Lisa K.; Sand, Kine Marita Knudsen & Gandhi, Amit K. [Show all 17 contributors for this article] (2020). FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 217(10). doi: 10.1084/jem.20200359.
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Caddy, Sarah L.; Vaysburd, Marina; Wing, Mark; Foss, Stian; Andersen, Jan Terje & O'Connell, Kevin [Show all 11 contributors for this article] (2020). Intracellular neutralisation of rotavirus by VP6-specific IgG. PLoS Pathogens. ISSN 1553-7366. 16(8), p. 1–18. doi: 10.1371/journal.ppat.1008732. Full text in Research Archive
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Azevedo, Claudia; Nilsen, Jeanette; Grevys, Algirdas; Nunes, Rute; Andersen, Jan Terje & Sarmento, Bruno (2020). Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin . Journal of Controlled Release. ISSN 0168-3659. doi: 10.1016/j.jconrel.2020.08.005.
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Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne & Holten, Aleksander Rygh [Show all 32 contributors for this article] (2020). Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients . Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 117(40), p. 25018–25025. doi: 10.1073/pnas.2010540117. Full text in Research Archive
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Bern, Malin C.; Nilsen, Jeannette; Ferrarese, Mattia; Sand, Kine Marita Knudsen; Tollefsrud Gjølberg, Torleif & Lode, Heidrun Elisabeth [Show all 24 contributors for this article] (2020). An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics. Science Translational Medicine. ISSN 1946-6234. 12(565), p. 1–13. doi: 10.1126/scitranslmed.abb0580. Full text in Research Archive
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Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar & Ludviksen, Judith K [Show all 11 contributors for this article] (2019). NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs. ISSN 1942-0862. 12:e1686319(1), p. 1–13. doi: 10.1080/19420862.2019.1686319. Full text in Research Archive Show summary
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Lode, Heidrun Elisabeth; Gjølberg, Torleif Tollefsrud ; Foss, Stian; Sivertsen, Magne S.; Brustugun, Jørgen & Andersson, Yvonne [Show all 9 contributors for this article] (2019). A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes. Scientific Reports. ISSN 2045-2322. 9:18021(1), p. 1–10. doi: 10.1038/s41598-019-54226-7. Full text in Research Archive Show summary
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Blumberg, Laurence J.; Humphries, John E.; Jones, Susan Dana; Pearce, L. Bruce; Holgate, Robert G.E. & Hearn, Arron R. [Show all 23 contributors for this article] (2019). Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Science Advances. ISSN 2375-2548. 5:eaax9586(12), p. 1–13. doi: 10.1126/sciadv.aax9586. Full text in Research Archive
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Foss, Stian; Bottermann, Maria; Jonsson, Alexandra; Sandlie, Inger; James, Leo C. & Andersen, Jan Terje (2019). TRIM21-From intracellular immunity to therapy. Frontiers in Immunology. ISSN 1664-3224. 10:2049, p. 1–14. doi: 10.3389/fimmu.2019.02049. Full text in Research Archive
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Maaland, Astri Fjelde; Heyerdahl, Helen; O'Shea, Adam; Eiriksdóttir, Bergthora; Pascal, Veronique & Andersen, Jan Terje [Show all 8 contributors for this article] (2019). Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003. European Journal of Nuclear Medicine and Molecular Imaging. ISSN 1619-7070. 46(11), p. 2311–2321. doi: 10.1007/s00259-019-04417-1. Full text in Research Archive
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Labzin, LI; Bottermann, M; Rodriguez-Silvestre, P; Foss, Stian; Andersen, Jan Terje & Vaysburd, M [Show all 8 contributors for this article] (2019). Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection. EMBO Journal. ISSN 0261-4189. doi: 10.15252/embj.2018101365. Full text in Research Archive
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Bottermann, Maria; Foss, Stian; Caddy, Sarah L.; Clift, Dean; van Tienen, Laurens M. & Vaysburd, Marina [Show all 16 contributors for this article] (2019). Complement C4 prevents viral infection through capsid inactivation. Cell Host and Microbe. ISSN 1931-3128. 25(4), p. 617–629. doi: 10.1016/j.chom.2019.02.016. Full text in Research Archive
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Pyzik, Michal; Sand, Kine Marita Knudsen; Hubbard, Jonathan J.; Andersen, Jan Terje; Sandlie, Inger & Blumberg, Richard S. (2019). The neonatal Fc Receptor (FcRn): A misnomer? Frontiers in Immunology. ISSN 1664-3224. 10:1540(JULY), p. 1–24. doi: 10.3389/fimmu.2019.01540. Full text in Research Archive
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Shaw, Alan; Hoffecker, Ian T.; Smyrlaki, Ioanna; Rosa, João; Grevys, Algirdas & Bryant-Bratlie, Diane Lynn [Show all 10 contributors for this article] (2019). Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies. Nature Nanotechnology. ISSN 1748-3387. 14(2), p. 184–190. doi: 10.1038/s41565-018-0336-3. Full text in Research Archive
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Nilsen, Jeannette; Bern, Malin C.; Sand, Kine Marita Knudsen; Grevys, Algirdas; Dalhus, Bjørn & Sandlie, Inger [Show all 7 contributors for this article] (2018). Human and mouse albumin bind their respective neonatal Fc receptors differently. Scientific Reports. ISSN 2045-2322. 8:14648, p. 1–12. doi: 10.1038/s41598-018-32817-0. Full text in Research Archive
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Bottermann, Maria; Foss, Stian; van Tienen, Laurens M.; Vaysburd, Marina; Cruickshank, James & O’Connell, Kevin [Show all 16 contributors for this article] (2018). TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 115(41), p. 10440–10445. doi: 10.1073/pnas.1806314115. Full text in Research Archive Show summary
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Grevys, Algirdas; Nilsen, Jeannette; Sand, Kine Marita Knudsen; Daba, Muluneh Bekele; Øynebråten, Inger & Bern, Malin C. [Show all 15 contributors for this article] (2018). A human endothelial cell-based recycling assay for screening of FcRn targeted molecules. Nature Communications. ISSN 2041-1723. 9. doi: 10.1038/s41467-018-03061-x. Full text in Research Archive
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Sivertsen, Magne S.; Jørstad, Øystein Kalsnes; Grevys, Algirdas; Foss, Stian; Moe, Morten Carsten & Andersen, Jan Terje (2018). Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties. Scientific Reports. ISSN 2045-2322. 8(1). doi: 10.1038/s41598-018-20525-8. Full text in Research Archive
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Stapleton, Nigel M.; Armstrong-Fisher, Sylvia S.; Andersen, Jan Terje; van der Schoot, C. Ellen; Porter, Charlene & Page, Kenneth R. [Show all 12 contributors for this article] (2018). Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport. Molecular Immunology. ISSN 0161-5890. 95, p. 1–9. doi: 10.1016/j.molimm.2018.01.006. Full text in Research Archive
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Nilsen, Jeannette; Sandlie, Inger; Roopenian, Derry C. & Andersen, Jan Terje (2018). Animal models for evaluation of albumin-based therapeutics. Current Opinion in Chemical Engineering. ISSN 2211-3398. 19, p. 68–76. doi: 10.1016/j.coche.2017.11.007. Full text in Research Archive Show summary
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Pyzik, Michal; Rath, Timo; Kuo, Timothy T.; Win, Sanda; Baker, Kristi & Hubbard, Jonathan J. [Show all 24 contributors for this article] (2017). Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 114(14), p. E2862–E2871. doi: 10.1073/pnas.1618291114. Full text in Research Archive
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Bottermann, Maria; Lode, Heidrun Elisabeth; Watkinson, Ruth E.; Foss, Stian; Sandlie, Inger & Andersen, Jan Terje [Show all 7 contributors for this article] (2017). Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity. Scientific Reports. ISSN 2045-2322. doi: 10.1038/srep45418. Full text in Research Archive
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Cardoso, Ines Do Rosario; Østerlund, Eva Christina; Stamnæs, Jorunn; Iversen, Rasmus; Andersen, Jan Terje & Jørgensen, Thomas J D [Show all 7 contributors for this article] (2017). Dissecting the interaction between transglutaminase 2 and fibronectin. Amino Acids. ISSN 0939-4451. 49(3), p. 489–500. doi: 10.1007/s00726-016-2296-y. Full text in Research Archive
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Bottermann, Maria; Lode, Heidrun Elisabeth; Watkinson, Ruth E; Foss, Stian; Sandlie, Inger & Andersen, Jan Terje [Show all 7 contributors for this article] (2016). Antibody-antigen kinetics constrain intracellular humoral immunity. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep37457. Full text in Research Archive
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Foss, Stian; Watkinson, Ruth E; Grevys, Algirdas; Mc, Adam Martin Berner; Bern, Malin C. & Høydahl, Lene Støkken [Show all 11 contributors for this article] (2016). TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity. Journal of Immunology. ISSN 0022-1767. 196(8), p. 3452–3459. doi: 10.4049/jimmunol.1502601. Full text in Research Archive
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Foss, Stian; Grevys, Algirdas; Sand, Kine Marita Knudsen; Bern, Malin C.; Blundell, Pat & Michaelsen, Terje Einar [Show all 9 contributors for this article] (2016). Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization. Journal of Controlled Release. ISSN 0168-3659. 223, p. 42–52. doi: 10.1016/j.jconrel.2015.12.033. Full text in Research Archive
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Foss, Stian; Watkinson, Ruth; Sandlie, Inger; James, Leo C. & Andersen, Jan Terje (2015). TRIM21: A cytosolic Fc receptor with broad antibody isotype specificity. Immunological Reviews. ISSN 0105-2896. 268(1), p. 328–339. doi: 10.1111/imr.12363. Full text in Research Archive
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Xi, Chien; Hnida, Kathrin; Graewert, Melissa Ann; Andersen, Jan Terje; Iversen, Rasmus & Tuukkanen, Anne [Show all 8 contributors for this article] (2015). Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease. Journal of Biological Chemistry. ISSN 0021-9258. 290(35), p. 21365–21375. doi: 10.1074/jbc.M115.669895.
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Cardoso, Ines Do Rosario; Stamnæs, Jorunn; Andersen, Jan Terje; Melino, Gerry; Iversen, Rasmus & Sollid, Ludvig Magne (2015). Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies. The FEBS Journal. ISSN 1742-464X. 282(11), p. 2063–2075. doi: 10.1111/febs.13276.
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Almåsbak, Hilde Kjersti; Walseng, Even; Kristian, Alexandr; Myhre, Marit Renee; Suso, Else Marit Inderberg & Munthe, Ludvig Andre [Show all 11 contributors for this article] (2015). Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model. Gene Therapy. ISSN 0969-7128. 22(5), p. 391–403. doi: 10.1038/gt.2015.4.
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Grevys, Algirdas; Bern, Malin C.; Foss, Stian; Bratlie, Diane Lynn Bryant; Moen, Anders & Gunnarsen, Kristin Støen [Show all 10 contributors for this article] (2015). Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions. Journal of Immunology. ISSN 0022-1767. 194(11), p. 5497–5508. doi: 10.4049/jimmunol.1401218. Full text in Research Archive
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Daniel M, Czajkowsky; Andersen, Jan Terje; Fuchs, Anja; Wilson, Timothy J; Mekhaiel, David & Colonna, Marco [Show all 17 contributors for this article] (2015). Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications. Scientific Reports. ISSN 2045-2322. 5, p. 1–11. doi: 10.1038/srep09526. Full text in Research Archive
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Bern, Malin C.; Sand, Kine Marita Knudsen; Nilsen, Jeannette; Sandlie, Inger & Andersen, Jan Terje (2015). The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery. Journal of Controlled Release. ISSN 0168-3659. 211, p. 144–162. doi: 10.1016/j.jconrel.2015.06.006.
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Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Noordzij, Hanna Theodora; Sandlie, Inger & Andersen, Jan Terje (2015). Unraveling the interaction between FcRn and albumin: Opportunities for design of albumin-based therapeutics. Frontiers in Immunology. ISSN 1664-3224. 5:682. doi: 10.3389/fimmu.2014.00682. Full text in Research Archive
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Hallstensen, Randi; Bergseth, Grete; Foss, Stian; Jæger, Steinar; Gedde-Dahl, Thobias & Holt, jan [Show all 14 contributors for this article] (2015). Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. Immunobiology. ISSN 0171-2985. 220(4), p. 452–459. doi: 10.1016/j.imbio.2014.11.003. Full text in Research Archive
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Andersen, Jan Terje; Hjelstuen, Ole Kristian & Sandlie, Inger (2014). From Basic Research to Innovation, Medical Technology - Meeting Tomorrow's Health Care Challenges. Novus Forlag. ISSN 978-82-7099-791-6. p. 39–50.
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Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Dalhus, Bjørn; Gunnarsen, Kristin Støen & Cameron, Jason [Show all 10 contributors for this article] (2014). Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc Receptor (FcRn). Journal of Biological Chemistry. ISSN 0021-9258. 289(50), p. 34583–34594. doi: 10.1074/jbc.M114.587675. Full text in Research Archive
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Einarsdottir, Helga K.; Stapleton, Nigel M.; Scherjon, Sicco; Andersen, Jan Terje; Rispens, Theo & van der Schoot, C. Ellen [Show all 7 contributors for this article] (2014). On the perplexingly low rate of transport of IgG2 across the human placenta. PLOS ONE. ISSN 1932-6203. 9(9). doi: 10.1371/journal.pone.0108319.
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Andersen, Jan Terje; Dalhus, Bjørn; Viuff, Dorthe; Ravn, Birgitte Thue; Gunnarsen, Kristin Støen & Plumridge, Andrew [Show all 17 contributors for this article] (2014). Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding. Journal of Biological Chemistry. ISSN 0021-9258. 289(19), p. 13492–13502. doi: 10.1074/jbc.M114.549832. Full text in Research Archive
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Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Dalhus, Bjørn; Gunnarsen, Kristin Støen & Cameron, Jason [Show all 10 contributors for this article] (2014). Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc Receptor (FcRn). Journal of Biological Chemistry. ISSN 0021-9258. 289(50), p. 34583–34594. doi: 10.1074/jbc.M114.587675.
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Sand, Kine Marita Knudsen; Dalhus, Bjørn; Christianson, Gregory J.; Bern, Malin C.; Foss, Stian & Cameron, Jason [Show all 11 contributors for this article] (2014). Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies. Journal of Biological Chemistry. ISSN 0021-9258. 289(24), p. 17228–17239. doi: 10.1074/jbc.M113.522565. Full text in Research Archive
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Rahman, Mohummad Aminur; Kristiansen, Per Eugen; Veiseth, Silje Veie; Andersen, Jan Terje; Yap, Kyoko L. & Zhou, Ming-Ming [Show all 9 contributors for this article] (2014). The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure. Biochemistry. ISSN 0006-2960. 53(13), p. 2091–2100. doi: 10.1021/bi401436h.
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Jung, Sang Taek; Kelton, William; Kang, Tae Hyun; T.W. Ng, Daphne; Andersen, Jan Terje & Sandlie, Inger [Show all 8 contributors for this article] (2013). Effective Phagocytosis of Low Her2 Tumor Cell Lines with Engineered, Aglycosylated IgG Displaying High FcγRIIa Affinity and Selectivity. ACS Chemical Biology. ISSN 1554-8929. 8(2), p. 368–375. doi: 10.1021/cb300455f.
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Yazaki, Paul J.; Lee, Brian; Channappal, Divya; Cheung, Chia-Wei; Crow, Desiree & Chea, Junie [Show all 15 contributors for this article] (2013). A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance. Protein Engineering Design & Selection. ISSN 1741-0126. 26(3), p. 187–193. doi: 10.1093/protein/gzs096.
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Mathiesen, Line; Nielsen, Leif K.; Andersen, Jan Terje; Grevys, Algirdas; Sandlie, Inger & Michaelsen, Terje Einar [Show all 9 contributors for this article] (2013). Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions. Blood. ISSN 0006-4971. 122(7), p. 1174–1181. doi: 10.1182/blood-2012-12-473843. Full text in Research Archive
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Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril & Pharo, Anne Margrethe [Show all 15 contributors for this article] (2013). Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology. ISSN 0022-1767. 191(9), p. 4769–4777. doi: 10.4049/jimmunol.1301653. Full text in Research Archive
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Jacobsen, Johanne Tracey; Gjerstad, Vibeke Sundvold; Skjeldal, Frode Miltzow; Andersen, Jan Terje; Abrahamsen, Greger & Bakke, Oddmund [Show all 8 contributors for this article] (2013). B-cell tolerance to the B-cell receptor variable regions. European Journal of Immunology. ISSN 0014-2980. 43(10), p. 2577–2587. doi: 10.1002/eji.201243203.
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Zakrzewicz, Anna; Würth, Celina; Beckert, Benedikt; Feldhoff, Simon; Vanderheyden, Katrien & Foss, Stian [Show all 11 contributors for this article] (2022). Correction: Zakrzewicz et al. Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? (Cells 2022, 11, 942). Cells. ISSN 2073-4409. 11(10). doi: 10.3390/cells11101700.
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König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, The Trung; Schikora-Rustad, Stine & Vaage, Eline Benno [Show all 22 contributors for this article] (2021). Humoral Immunity to SARS-CoV-2 mRNA Vaccination in People with Multiple Sclerosis using High-Efficacy Disease Modifying Therapies.
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Grødeland, Gunnveig; Fossum, Even & Andersen, Jan Terje (2020). Vaksinepodden.no: Antistoffer.
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Jørstad, Øystein Kalsnes; Sivertsen, Magne S.; Andersen, Jan Terje & Moe, Morten Carsten (2020). Kan ampullene med covid-19-vaksine utnyttes bedre? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 20.1039. doi: 10.4045/tidsskr.20.1039.
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Andersen, Jan Terje (2020). Fikk Trump en magisk cocktail av antistoffer? Aftenposten Viten. ISSN 2464-3033.
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Andersen, Jan Terje (2019). Design of affordable anti-HIV antibodies.
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Andersen, Jan Terje (2019). Langtidsvirkende, forebyggende hiv-medisin.
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Andersen, Jan Terje; Sakya, Siri Aastedatter; Foss, Stian; Sandlie, Inger & Voets, Ardi (2019). Is an HIV vaccine within reach? Vaksinebloggen.
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Andersen, Jan Terje; Sakya, Siri Aastedatter; Foss, Stian & Sandlie, Inger (2019). Hvordan kan moderne medisin forebygge HIV? Medisinbloggen.
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Andersen, Jan Terje & Kalveland, Julie (2019). Får millioner til å forske på hiv. [Newspaper]. Dagens Medisin.
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Vestrum, Alexander & Andersen, Jan Terje (2019). Norske millioner til forskning på hiv-medisin for kvinner . [Journal]. Bistandsaktuelt.
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Vestrum, Alexander & Andersen, Jan Terje (2019). Millioner til forskning på hiv-medisin for kvinner. [Newspaper]. VG.
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Shaw, Alan; Hoffecker, Ian T.; Smyrlaki, Ioanna; Rosa, João; Grevys, Algirdas & Bryant-Bratlie, Diane Lynn [Show all 10 contributors for this article] (2019). Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies. Nature Nanotechnology. ISSN 1748-3387. 14(4), p. 398–398. doi: 10.1038/s41565-019-0404-3.
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Tunheim, Gro; Kran, Anne-Marte Bakken; Rø, Gunnar Øyvind Isaksson; Hungnes, Olav; Lund-Johansen, Fridtjof & Tran, Trung [Show all 8 contributors for this article] (2020). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in late summer 2020. Folkehelseinstituttet. ISSN 978-82-8406-155-9. Show summary
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Tunheim, Gro; Kran, Anne-Marte Bakken; Rø, Gunnar Øyvind Isaksson; Steens, Anneke; Hungnes, Olav & Lund-Johansen, Fridtjof [Show all 9 contributors for this article] (2020). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in April/May 2020 and August 2019. Folkehelseinstituttet. ISSN 978-82-8406-109-2. Show summary
Published
Jan. 22, 2018 9:57 AM
- Last modified
May 5, 2020 2:38 PM