Jan Terje Andersen
Professor
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Department of Pharmacology

Norwegian version of this page
Phone
+47 22857275
Username
Visiting address
Sognsvannsveien 20
Rikshospitalet
0372 Oslo
Postal address
Postboks 1057 Blindern
0316 Oslo
Publications
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Akbar, Rahmad; Robert, Philippe Paul Auguste; Weber, Cédric R.; Widrich, Michael; Frank, Robert & Pavlovic, Milena [Show all 19 contributors for this article] (2022). In silico proof of principle of machine learning-based antibody design at unconstrained scale. mAbs. ISSN 1942-0862. doi: 10.1080/19420862.2022.2031482.
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Grevys, Algirdas; Frick, Rahel; Mester, Simone; Flem-Karlsen, Karine; Nilsen, Jeannette & Foss, Stian [Show all 13 contributors for this article] (2022). Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life. iScience. ISSN 2589-0042. 25(2). doi: 10.1016/j.isci.2022.103746.
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Akbar, Rahmad; Bashour, Habib; Rawat, Puneet; Robert, Philippe Paul Auguste; Smorodina, Eva & Cotet, Tudor-Stefan [Show all 15 contributors for this article] (2022). Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies. mAbs. ISSN 1942-0862. 14(1). doi: 10.1080/19420862.2021.2008790.
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Sivertsen, Magne S.; Lode, Heidrun Elisabeth; Tollefsrud Gjølberg, Torleif; Petrovski, Goran; Andersen, Jan Terje & Jørstad, Øystein Kalsnes [Show all 7 contributors for this article] (2021). Cluster of symptomatic silicone oil droplets following intravitreal injections: A 1-year observational study. BMJ Open Ophthalmology. ISSN 2397-3269. 6:e000764(1), p. 1–5. doi: 10.1136/bmjophth-2021-000764. Full text in Research Archive
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Azevedo, Cláudia; Pinto, Soraia; Benjakul, Sopisa; Nilsen, Jeannette; Santos, Helder A. & Traverso, Giovanni [Show all 8 contributors for this article] (2021). Prevention of diabetes-associated fibrosis: Strategies in FcRn-targeted nanosystems for oral drug delivery. Advanced Drug Delivery Reviews. ISSN 0169-409X. 175. doi: 10.1016/j.addr.2021.04.016. Full text in Research Archive
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Christopoulos, Panagiotis; Gjølberg, Torleif Tollefsrud; Krüger, Stig; Haraldsen, Guttorm; Andersen, Jan Terje & Sundlisæter, Eirik (2021). Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases. Frontiers in Immunology. ISSN 1664-3224. 12:668207, p. 1–22. doi: 10.3389/fimmu.2021.668207. Full text in Research Archive
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Azevedo, Cláudia; Andersen, Jan Terje; Traverso, Giovanni & Sarmento, Bruno (2021). The potential of porcine ex vivo platform for intestinal permeability screening of FcRn-targeted drugs. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 162, p. 99–104. doi: 10.1016/j.ejpb.2021.03.009.
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König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, Trung; Schikora-Rustad, Stine & Vaage, Eline Benno [Show all 22 contributors for this article] (2021). Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations. Journal of Neurology, Neurosurgery and Psychiatry. ISSN 0022-3050. doi: 10.1136/jnnp-2021-327612. Full text in Research Archive
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Tunheim, Gro; Rø, Gunnar Øyvind Isaksson; Tran, Trung; Kran, Anne-Marte Bakken; Andersen, Jan Terje & Vaage, Eline Benno [Show all 10 contributors for this article] (2021). Trends in seroprevalence of SARS-CoV-2 and infection fatality rate in the Norwegian population through the first year of the COVID-19 pandemic. Influenza and Other Respiratory Viruses. ISSN 1750-2640. 16(2), p. 204–212. doi: 10.1111/irv.12932. Full text in Research Archive
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Merten, Hannes; Brandl, Fabian; Zimmermann, Martina; Schaefer, Jonas V.; Irpinio, Linda & Sand, Kine M.K. [Show all 10 contributors for this article] (2021). Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling. European journal of pharmaceutics and biopharmaceutics. ISSN 0939-6411. 167, p. 104–113. doi: 10.1016/j.ejpb.2021.07.011. Full text in Research Archive
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Mester, Simone; Evers, Mitchell; Meyer, Saskia; Nilsen, Jeannette; Greiff, Victor & Sandlie, Inger [Show all 8 contributors for this article] (2021). Extended plasma half-life of albumin-binding domain fused human IgA upon pH-dependent albumin engagement of human FcRn in vitro and in vivo. mAbs. ISSN 1942-0862. 13:1893888(1), p. 1–14. doi: 10.1080/19420862.2021.1893888. Full text in Research Archive
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Mandrup, Ole A.; Ong, Sui Ching; Lykkemark, Simon; Dinesen, Anders; Rudnik-Jansen, Imke & Dagnæs-Hansen, Niels Frederik [Show all 9 contributors for this article] (2021). Programmable half-life and anti-tumour effects of bispecific T-cell engager-albumin fusions with tuned FcRn affinity. Communications Biology. ISSN 2399-3642. 4:310(1), p. 1–11. doi: 10.1038/s42003-021-01790-2. Full text in Research Archive
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Lombardi, Silvia; Hovden Aaen, Kristin; Nilsen, Jeannette; Ferrarese, Mattia; Tollefsrud Gjølberg, Torleif & Bernardi, Francesco [Show all 9 contributors for this article] (2021). Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity. British Journal of Haematology. ISSN 0007-1048. 194(2), p. 453–462. doi: 10.1111/bjh.17559. Full text in Research Archive
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Høydahl, Lene; Frigstad, Terje; Rasmussen, Ingunn B; Øynebråten, Inger; Schjetne, Karoline W & Andersen, Jan Terje [Show all 10 contributors for this article] (2021). Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses. Vaccine. ISSN 0264-410X. 39(11), p. 1583–1592. doi: 10.1016/j.vaccine.2021.02.012. Full text in Research Archive
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Caddy, Sarah L.; Vaysburd, Marina; Papa, Guido; Wing, Mark; O'Connell, Kevin & Stoycheva, Diana [Show all 10 contributors for this article] (2020). Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity. EMBO Journal. ISSN 0261-4189. 40:e106228(5), p. 1–9. doi: 10.15252/embj.2020106228. Full text in Research Archive
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Schrottmaier, Waltraud C.; Salzmann, Manuel; Badrnya, Sigrun; Mussbacher, Marion; Kral-Pointer, Julia B. & Morava, Susanne [Show all 17 contributors for this article] (2020). Platelets mediate serological memory to neutralize viruses in vitro and in vivo. Blood Advances. ISSN 2473-9529. 4(16), p. 3971–3976. doi: 10.1182/bloodadvances.2020001786. Full text in Research Archive
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Hovden Aaen, Kristin; Anthi, Aina Karen; Sandlie, Inger; Nilsen, Jeannette; Mester, Simone & Andersen, Jan Terje (2020). The neonatal Fc receptor in mucosal immune regulation. Scandinavian Journal of Immunology. ISSN 0300-9475. doi: 10.1111/sji.13017.
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Nilsen, Jeannette; Trabjerg, Esben; Grevys, Algirdas; Azevedo, Claudia; Brennan, Stephen O. & Stensland, Maria [Show all 14 contributors for this article] (2020). An intact C-terminal end of albumin is required for its long half-life in humans. Communications Biology. ISSN 2399-3642. 3(1). doi: 10.1038/s42003-020-0903-7. Full text in Research Archive
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Hubbard, Jonathan J.; Pyzik, Michal; Rath, Timo; Kozicky, Lisa K.; Sand, Kine Marita Knudsen & Gandhi, Amit K. [Show all 17 contributors for this article] (2020). FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 217(10). doi: 10.1084/jem.20200359.
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Caddy, Sarah L.; Vaysburd, Marina; Wing, Mark; Foss, Stian; Andersen, Jan Terje & O'Connell, Kevin [Show all 11 contributors for this article] (2020). Intracellular neutralisation of rotavirus by VP6-specific IgG. PLoS Pathogens. ISSN 1553-7366. 16:e1008732(8), p. 1–18. doi: 10.1371/journal.ppat.1008732. Full text in Research Archive
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Azevedo, Claudia; Nilsen, Jeanette; Grevys, Algirdas; Nunes, Rute; Andersen, Jan Terje & Sarmento, Bruno (2020). Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin . Journal of Controlled Release. ISSN 0168-3659. doi: 10.1016/j.jconrel.2020.08.005.
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Holter, Jan Cato; Pischke, Soeren; de Boer, Eline; Lind, Andreas; Jenum, Synne & Holten, Aleksander Rygh [Show all 32 contributors for this article] (2020). Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients . Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 117(40), p. 25018–25025. doi: 10.1073/pnas.2010540117. Full text in Research Archive
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Bern, Malin C.; Nilsen, Jeannette; Ferrarese, Mattia; Sand, Kine Marita Knudsen; Tollefsrud Gjølberg, Torleif & Lode, Heidrun Elisabeth [Show all 24 contributors for this article] (2020). An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics. Science Translational Medicine. ISSN 1946-6234. 12(565), p. 1–13. doi: 10.1126/scitranslmed.abb0580. Full text in Research Archive
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Lau, Corinna; McAdam, Martin Berner; Bergseth, Grete; Grevys, Algirdas; Bruun, Jack-Ansgar & Ludviksen, Judith K [Show all 11 contributors for this article] (2019). NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies. mAbs. ISSN 1942-0862. 12:e1686319(1), p. 1–13. doi: 10.1080/19420862.2019.1686319. Full text in Research Archive Show summary
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Lode, Heidrun Elisabeth; Gjølberg, Torleif Tollefsrud ; Foss, Stian; Sivertsen, Magne S.; Brustugun, Jørgen & Andersson, Yvonne [Show all 9 contributors for this article] (2019). A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes. Scientific Reports. ISSN 2045-2322. 9:18021(1), p. 1–10. doi: 10.1038/s41598-019-54226-7. Full text in Research Archive Show summary
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Blumberg, Laurence J.; Humphries, John E.; Jones, Susan Dana; Pearce, L. Bruce; Holgate, Robert G.E. & Hearn, Arron R. [Show all 23 contributors for this article] (2019). Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Science Advances. ISSN 2375-2548. 5:eaax9586(12), p. 1–13. doi: 10.1126/sciadv.aax9586. Full text in Research Archive
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Foss, Stian; Bottermann, Maria; Jonsson, Alexandra; Sandlie, Inger; James, Leo C. & Andersen, Jan Terje (2019). TRIM21-From intracellular immunity to therapy. Frontiers in Immunology. ISSN 1664-3224. 10:2049, p. 1–14. doi: 10.3389/fimmu.2019.02049. Full text in Research Archive
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Maaland, Astri Fjelde; Heyerdahl, Helen; O'Shea, Adam; Eiriksdóttir, Bergthora; Pascal, Veronique & Andersen, Jan Terje [Show all 8 contributors for this article] (2019). Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate 177Lu-NNV003. European Journal of Nuclear Medicine and Molecular Imaging. ISSN 1619-7070. 46(11), p. 2311–2321. doi: 10.1007/s00259-019-04417-1. Full text in Research Archive
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Labzin, LI; Bottermann, M; Rodriguez-Silvestre, P; Foss, Stian; Andersen, Jan Terje & Vaysburd, M [Show all 8 contributors for this article] (2019). Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection. EMBO Journal. ISSN 0261-4189. doi: 10.15252/embj.2018101365. Full text in Research Archive
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Bottermann, Maria; Foss, Stian; Caddy, Sarah L.; Clift, Dean; van Tienen, Laurens M. & Vaysburd, Marina [Show all 16 contributors for this article] (2019). Complement C4 prevents viral infection through capsid inactivation. Cell Host and Microbe. ISSN 1931-3128. 25(4), p. 617–629. doi: 10.1016/j.chom.2019.02.016. Full text in Research Archive
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Pyzik, Michal; Sand, Kine Marita Knudsen; Hubbard, Jonathan J.; Andersen, Jan Terje; Sandlie, Inger & Blumberg, Richard S. (2019). The neonatal Fc Receptor (FcRn): A misnomer? Frontiers in Immunology. ISSN 1664-3224. 10:1540(JULY), p. 1–24. doi: 10.3389/fimmu.2019.01540. Full text in Research Archive
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Shaw, Alan; Hoffecker, Ian T.; Smyrlaki, Ioanna; Rosa, João; Grevys, Algirdas & Bryant-Bratlie, Diane Lynn [Show all 10 contributors for this article] (2019). Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies. Nature Nanotechnology. ISSN 1748-3387. 14(2), p. 184–190. doi: 10.1038/s41565-018-0336-3.
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Nilsen, Jeannette; Bern, Malin C.; Sand, Kine Marita Knudsen; Grevys, Algirdas; Dalhus, Bjørn & Sandlie, Inger [Show all 7 contributors for this article] (2018). Human and mouse albumin bind their respective neonatal Fc receptors differently. Scientific Reports. ISSN 2045-2322. 8:14648, p. 1–12. doi: 10.1038/s41598-018-32817-0. Full text in Research Archive
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Bottermann, Maria; Foss, Stian; van Tienen, Laurens M.; Vaysburd, Marina; Cruickshank, James & O’Connell, Kevin [Show all 16 contributors for this article] (2018). TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 115(41), p. 10440–10445. doi: 10.1073/pnas.1806314115. Full text in Research Archive
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Grevys, Algirdas; Nilsen, Jeannette; Sand, Kine Marita Knudsen; Daba, Muluneh Bekele; Øynebråten, Inger & Bern, Malin C. [Show all 15 contributors for this article] (2018). A human endothelial cell-based recycling assay for screening of FcRn targeted molecules. Nature Communications. ISSN 2041-1723. 9. doi: 10.1038/s41467-018-03061-x. Full text in Research Archive
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Sivertsen, Magne S.; Jørstad, Øystein Kalsnes; Grevys, Algirdas; Foss, Stian; Moe, Morten Carsten & Andersen, Jan Terje (2018). Pharmaceutical compounding of aflibercept in prefilled syringes does not affect structural integrity, stability or VEGF and Fc binding properties. Scientific Reports. ISSN 2045-2322. 8(1). doi: 10.1038/s41598-018-20525-8. Full text in Research Archive
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Stapleton, Nigel M.; Armstrong-Fisher, Sylvia S.; Andersen, Jan Terje; van der Schoot, C. Ellen; Porter, Charlene & Page, Kenneth R. [Show all 12 contributors for this article] (2018). Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport. Molecular Immunology. ISSN 0161-5890. 95, p. 1–9. doi: 10.1016/j.molimm.2018.01.006. Full text in Research Archive
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Nilsen, Jeannette; Sandlie, Inger; Roopenian, Derry C. & Andersen, Jan Terje (2018). Animal models for evaluation of albumin-based therapeutics. Current Opinion in Chemical Engineering. ISSN 2211-3398. 19, p. 68–76. doi: 10.1016/j.coche.2017.11.007. Full text in Research Archive
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Pyzik, Michal; Rath, Timo; Kuo, Timothy T.; Win, Sanda; Baker, Kristi & Hubbard, Jonathan J. [Show all 24 contributors for this article] (2017). Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 114(14), p. E2862–E2871. doi: 10.1073/pnas.1618291114. Full text in Research Archive
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Bottermann, Maria; Lode, Heidrun Elisabeth; Watkinson, Ruth E.; Foss, Stian; Sandlie, Inger & Andersen, Jan Terje [Show all 7 contributors for this article] (2017). Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity. Scientific Reports. ISSN 2045-2322. doi: 10.1038/srep45418. Full text in Research Archive
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Cardoso, Ines Do Rosario; Østerlund, Eva Christina; Stamnæs, Jorunn; Iversen, Rasmus; Andersen, Jan Terje & Jørgensen, Thomas J D [Show all 7 contributors for this article] (2017). Dissecting the interaction between transglutaminase 2 and fibronectin. Amino Acids. ISSN 0939-4451. 49(3), p. 489–500. doi: 10.1007/s00726-016-2296-y. Full text in Research Archive
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Bottermann, Maria; Lode, Heidrun Elisabeth; Watkinson, Ruth E; Foss, Stian; Sandlie, Inger & Andersen, Jan Terje [Show all 7 contributors for this article] (2016). Antibody-antigen kinetics constrain intracellular humoral immunity. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep37457. Full text in Research Archive
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Foss, Stian; Watkinson, Ruth E; Grevys, Algirdas; Mc, Adam Martin Berner; Bern, Malin C. & Høydahl, Lene Støkken [Show all 11 contributors for this article] (2016). TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity. Journal of Immunology. ISSN 0022-1767. 196(8), p. 3452–3459. doi: 10.4049/jimmunol.1502601. Full text in Research Archive
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Foss, Stian; Grevys, Algirdas; Sand, Kine Marita Knudsen; Bern, Malin C.; Blundell, Pat & Michaelsen, Terje Einar [Show all 9 contributors for this article] (2016). Enhanced FcRn-dependent transepithelial delivery of IgG by Fc-engineering and polymerization. Journal of Controlled Release. ISSN 0168-3659. 223, p. 42–52. doi: 10.1016/j.jconrel.2015.12.033. Full text in Research Archive
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Foss, Stian; Watkinson, Ruth; Sandlie, Inger; James, Leo C. & Andersen, Jan Terje (2015). TRIM21: A cytosolic Fc receptor with broad antibody isotype specificity. Immunological Reviews. ISSN 0105-2896. 268(1), p. 328–339. doi: 10.1111/imr.12363. Full text in Research Archive
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Xi, Chien; Hnida, Kathrin; Graewert, Melissa Ann; Andersen, Jan Terje; Iversen, Rasmus & Tuukkanen, Anne [Show all 8 contributors for this article] (2015). Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease. Journal of Biological Chemistry. ISSN 0021-9258. 290(35), p. 21365–21375. doi: 10.1074/jbc.M115.669895.
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Cardoso, Ines Do Rosario; Stamnæs, Jorunn; Andersen, Jan Terje; Melino, Gerry; Iversen, Rasmus & Sollid, Ludvig Magne (2015). Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies. The FEBS Journal. ISSN 1742-464X. 282(11), p. 2063–2075. doi: 10.1111/febs.13276.
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Almåsbak, Hilde Kjersti; Walseng, Even; Kristian, Alexandr; Myhre, Marit Renee; Suso, Else Marit Inderberg & Munthe, Ludvig Andre [Show all 11 contributors for this article] (2015). Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model. Gene Therapy. ISSN 0969-7128. 22(5), p. 391–403. doi: 10.1038/gt.2015.4.
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Grevys, Algirdas; Bern, Malin C.; Foss, Stian; Bratlie, Diane Lynn Bryant; Moen, Anders & Gunnarsen, Kristin Støen [Show all 10 contributors for this article] (2015). Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions. Journal of Immunology. ISSN 0022-1767. 194(11), p. 5497–5508. doi: 10.4049/jimmunol.1401218. Full text in Research Archive
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Daniel M, Czajkowsky; Andersen, Jan Terje; Fuchs, Anja; Wilson, Timothy J; Mekhaiel, David & Colonna, Marco [Show all 17 contributors for this article] (2015). Developing the IVIG biomimetic, Hexa-Fc, for drug and vaccine applications. Scientific Reports. ISSN 2045-2322. 5, p. 1–11. doi: 10.1038/srep09526. Full text in Research Archive
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Bern, Malin C.; Sand, Kine Marita Knudsen; Nilsen, Jeannette; Sandlie, Inger & Andersen, Jan Terje (2015). The role of albumin receptors in regulation of albumin homeostasis: Implications for drug delivery. Journal of Controlled Release. ISSN 0168-3659. 211, p. 144–162. doi: 10.1016/j.jconrel.2015.06.006.
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Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Noordzij, Hanna Theodora; Sandlie, Inger & Andersen, Jan Terje (2015). Unraveling the interaction between FcRn and albumin: Opportunities for design of albumin-based therapeutics. Frontiers in Immunology. ISSN 1664-3224. 5:682. doi: 10.3389/fimmu.2014.00682. Full text in Research Archive
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Hallstensen, Randi; Bergseth, Grete; Foss, Stian; Jæger, Steinar; Gedde-Dahl, Thobias & Holt, jan [Show all 14 contributors for this article] (2015). Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. Immunobiology. ISSN 0171-2985. 220(4), p. 452–459. doi: 10.1016/j.imbio.2014.11.003. Full text in Research Archive
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Andersen, Jan Terje; Hjelstuen, Ole Kristian & Sandlie, Inger (2014). From Basic Research to Innovation, Medical Technology - Meeting Tomorrow's Health Care Challenges. Novus Forlag. ISSN 978-82-7099-791-6. p. 39–50.
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Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Dalhus, Bjørn; Gunnarsen, Kristin Støen & Cameron, Jason [Show all 10 contributors for this article] (2014). Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc Receptor (FcRn). Journal of Biological Chemistry. ISSN 0021-9258. 289(50), p. 34583–34594. doi: 10.1074/jbc.M114.587675. Full text in Research Archive
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Einarsdottir, Helga K.; Stapleton, Nigel M.; Scherjon, Sicco; Andersen, Jan Terje; Rispens, Theo & van der Schoot, C. Ellen [Show all 7 contributors for this article] (2014). On the perplexingly low rate of transport of IgG2 across the human placenta. PLOS ONE. ISSN 1932-6203. 9(9). doi: 10.1371/journal.pone.0108319.
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Andersen, Jan Terje; Dalhus, Bjørn; Viuff, Dorthe; Ravn, Birgitte Thue; Gunnarsen, Kristin Støen & Plumridge, Andrew [Show all 17 contributors for this article] (2014). Extending serum half-life of albumin by engineering neonatal Fc receptor (FcRn) binding. Journal of Biological Chemistry. ISSN 0021-9258. 289(19), p. 13492–13502. doi: 10.1074/jbc.M114.549832. Full text in Research Archive
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Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Dalhus, Bjørn; Gunnarsen, Kristin Støen & Cameron, Jason [Show all 10 contributors for this article] (2014). Interaction with both domain I and III of albumin is required for optimal pH-dependent binding to the neonatal Fc Receptor (FcRn). Journal of Biological Chemistry. ISSN 0021-9258. 289(50), p. 34583–34594. doi: 10.1074/jbc.M114.587675.
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Sand, Kine Marita Knudsen; Dalhus, Bjørn; Christianson, Gregory J.; Bern, Malin C.; Foss, Stian & Cameron, Jason [Show all 11 contributors for this article] (2014). Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies. Journal of Biological Chemistry. ISSN 0021-9258. 289(24), p. 17228–17239. doi: 10.1074/jbc.M113.522565. Full text in Research Archive
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Rahman, Mohummad Aminur; Kristiansen, Per Eugen; Veiseth, Silje Veie; Andersen, Jan Terje; Yap, Kyoko L. & Zhou, Ming-Ming [Show all 9 contributors for this article] (2014). The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure. Biochemistry. ISSN 0006-2960. 53(13), p. 2091–2100. doi: 10.1021/bi401436h.
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Jung, Sang Taek; Kelton, William; Kang, Tae Hyun; T.W. Ng, Daphne; Andersen, Jan Terje & Sandlie, Inger [Show all 8 contributors for this article] (2013). Effective Phagocytosis of Low Her2 Tumor Cell Lines with Engineered, Aglycosylated IgG Displaying High FcγRIIa Affinity and Selectivity. ACS Chemical Biology. ISSN 1554-8929. 8(2), p. 368–375. doi: 10.1021/cb300455f.
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Yazaki, Paul J.; Lee, Brian; Channappal, Divya; Cheung, Chia-Wei; Crow, Desiree & Chea, Junie [Show all 15 contributors for this article] (2013). A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance. Protein Engineering Design & Selection. ISSN 1741-0126. 26(3), p. 187–193. doi: 10.1093/protein/gzs096.
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Mathiesen, Line; Nielsen, Leif K.; Andersen, Jan Terje; Grevys, Algirdas; Sandlie, Inger & Michaelsen, Terje Einar [Show all 9 contributors for this article] (2013). Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions. Blood. ISSN 0006-4971. 122(7), p. 1174–1181. doi: 10.1182/blood-2012-12-473843. Full text in Research Archive
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Lau, Corinna; Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Andersen, Jan Terje; Berntzen, Gøril & Pharo, Anne Margrethe [Show all 15 contributors for this article] (2013). Chimeric Anti-CD14 IGG2/4 Hybrid Antibodies for Therapeutic Intervention in Pig and Human Models of Inflammation. Journal of Immunology. ISSN 0022-1767. 191(9), p. 4769–4777. doi: 10.4049/jimmunol.1301653. Full text in Research Archive
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Jacobsen, Johanne Tracey; Gjerstad, Vibeke Sundvold; Skjeldal, Frode Miltzow; Andersen, Jan Terje; Abrahamsen, Greger & Bakke, Oddmund [Show all 8 contributors for this article] (2013). B-cell tolerance to the B-cell receptor variable regions. European Journal of Immunology. ISSN 0014-2980. 43(10), p. 2577–2587. doi: 10.1002/eji.201243203.
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Andersen, Jan Terje; Cameron, J; Plumridge, A; Sleep, D; Evans, L & Sandlie, Inger (2013). Single-chain Variable Fragment Albumin Fusions Bind the Neonatal Fc Receptor (FcRn) in a Species-dependent Manner: IMPLICATIONS FOR IN VIVO HALF-LIFE EVALUATION OF ALBUMIN FUSION THERAPEUTICS. Journal of Biological Chemistry. ISSN 0021-9258. 288(33), p. 24277–24285. doi: 10.1074/jbc.M113.463000. Full text in Research Archive
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Andersen, Jan Terje; Gonzalez-Pajuelo, Maria; Foss, Stian; Landsverk, Ole J. B.; Pinto, Debora & Szyroki, Alexander [Show all 10 contributors for this article] (2013). Selection of Nanobodies that Target Human Neonatal Fc Receptor. Scientific Reports. ISSN 2045-2322. 3. doi: 10.1038/srep01118. Full text in Research Archive
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Andersen, Jan Terje; Foss, Stian; Kenanova, Vania E; Olafsen, Tove; Leikfoss, Ingvild Sørum & Roopenian, Derry C [Show all 8 contributors for this article] (2012). Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life. Journal of Biological Chemistry. ISSN 0021-9258. 287(27), p. 22927–22937. doi: 10.1074/jbc.M112.355131. Full text in Research Archive
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Andersen, Jan Terje; Dalhus, Bjørn; Cameron, Jason; Daba, Muluneh Bekele; Plumridge, Andrew & Evans, Leslie [Show all 11 contributors for this article] (2012). Structure-based mutagenesis reveals the albumin-binding site of the neonatal Fc receptor. Nature Communications. ISSN 2041-1723. 3. doi: 10.1038/ncomms1607. Full text in Research Archive
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Stapleton, NM; Andersen, Jan Terje; Stemerding, AM; Bjarnarson, SP; Verheul, RC & Gerritsen, J. [Show all 13 contributors for this article] (2011). Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential. Nature Communications. ISSN 2041-1723. 2. doi: 10.1038/ncomms1608. Full text in Research Archive Show summary
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Mekhaiel, David N. A.; Czajkowsky, Daniel M.; Andersen, Jan Terje; Shi, Jianguo; El-Faham, Marwa & Doenhoff, Michael [Show all 12 contributors for this article] (2011). Polymeric human Fc-fusion proteins with modified effector functions. Scientific Reports. ISSN 2045-2322. 1. doi: 10.1038/srep00124. Full text in Research Archive
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Baker, Kristi; Qiao, Shuo Wang; Kuo, Timothy T.; Aveson, Victoria G.; Platzer, Barbara & Andersen, Jan Terje [Show all 12 contributors for this article] (2011). Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8(-)CD11b(+) dendritic cells. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 108(24), p. 9927–9932. doi: 10.1073/pnas.1019037108.
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Andersen, Jan Terje; Pehrson, Rikard; Tolmachev, Vladimir; Daba, Muluneh Bekele; Abrahamsen, Lars & Ekblad, Caroline (2011). Extending Half-life by Indirect Targeting of the Neonatal Fc Receptor (FcRn) Using a Minimal Albumin Binding Domain. Journal of Biological Chemistry. ISSN 0021-9258. 286(7), p. 5234–5241. doi: 10.1074/jbc.M110.164848.
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Andersen, Jan Terje; Daba, Muluneh Bekele & Sandlie, Inger (2010). FcRn binding properties of an abnormal truncated analbuminemic albumin variant. Clinical Biochemistry. ISSN 0009-9120. 43(4-5), p. 367–372. doi: 10.1016/j.clinbiochem.2009.12.001.
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Andersen, Jan Terje; Daba, Muluneh Bekele; Berntzen, Gøril; Michaelsen, Terje Einar & Sandlie, Inger (2010). Cross-species binding analyses of mouse and human neonatal Fc receptor show dramatic differences in immunoglobulin G and albumin binding. Journal of Biological Chemistry. ISSN 0021-9258. 285(7), p. 4826–4836. doi: 10.1074/jbc.M109.081828. Full text in Research Archive
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Andersen, Jan Terje & Sandlie, Inger (2009). The Versatile MHC Class I-related FcRn Protects IgG and Albumin from Degradation: Implications for Development of New Diagnostics and Therapeutics. Drug Metabolism and Pharmacokinetics (DMPK). ISSN 1347-4367. 24(4), p. 318–332.
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Berntzen, Gøril; Andersen, Jan Terje; Ustgård, Kristine; Ustgård, Kristine; Michaelsen, Terje Einar & Mousavi, Darbi Seyed Ali [Show all 13 contributors for this article] (2009). Identification of a High Affinity Fc gamma RIIA-binding Peptide That Distinguishes Fc gamma RIIA from Fc gamma RIIB and Exploits Fc gamma RIIA-mediated Phagocytosis and Degradation. Journal of Biological Chemistry. ISSN 0021-9258. 284(2), p. 1126–1135. doi: 10.1074/jbc.M803584200. Full text in Research Archive
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Andersen, Jan Terje & Sandlie, Inger (2011). Pharmacokinetics of IgG and albumin: The impact of FcRn for Design of Drug Delivery Systems: The impact of FcRn for Design of Drug Delivery Systems. Wiley-VCH Verlag GmbH. ISBN 9783527328239. 34 p.
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Andersen, Jan Terje & Sandlie, Inger (2011). Extending Antibody Half Lives with Albumin In: Recombinant Antibodies for Immunotherapy. Cambridge University Press. ISBN 9780521887328. 17 p.
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Andersen, Jan Terje; Sandlie, Inger; Kenanova, Vania E; Olafsen, Tove & Wu, Anna M (2010). Engineering of the Fc Region for Improved PK (FcRn interaction. Springer-Verlag Berlin Heidelberg . ISBN 978-3-642-01143-6. 19 p.
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König, Marton; Lorentzen, Åslaug Rudjord; Torgauten, Hilde Marie; Tran, The Trung; Schikora-Rustad, Stine & Vaage, Eline Benno [Show all 22 contributors for this article] (2021). Humoral Immunity to SARS-CoV-2 mRNA Vaccination in People with Multiple Sclerosis using High-Efficacy Disease Modifying Therapies.
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Grødeland, Gunnveig; Fossum, Even & Andersen, Jan Terje (2020). Vaksinepodden.no: Antistoffer.
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Jørstad, Øystein Kalsnes; Sivertsen, Magne S.; Andersen, Jan Terje & Moe, Morten Carsten (2020). Kan ampullene med covid-19-vaksine utnyttes bedre? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 20.1039. doi: 10.4045/tidsskr.20.1039.
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Andersen, Jan Terje (2020). Fikk Trump en magisk cocktail av antistoffer? Aftenposten Viten. ISSN 2464-3033.
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Andersen, Jan Terje (2019). Design of affordable anti-HIV antibodies.
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Andersen, Jan Terje (2019). Langtidsvirkende, forebyggende hiv-medisin.
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Andersen, Jan Terje; Sakya, Siri Aastedatter; Foss, Stian; Sandlie, Inger & Voets, Ardi (2019). Is an HIV vaccine within reach? Vaksinebloggen.
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Andersen, Jan Terje; Sakya, Siri Aastedatter; Foss, Stian & Sandlie, Inger (2019). Hvordan kan moderne medisin forebygge HIV? Medisinbloggen.
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Andersen, Jan Terje & Kalveland, Julie (2019). Får millioner til å forske på hiv. [Newspaper]. Dagens Medisin.
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Vestrum, Alexander & Andersen, Jan Terje (2019). Norske millioner til forskning på hiv-medisin for kvinner . [Journal]. Bistandsaktuelt.
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Vestrum, Alexander & Andersen, Jan Terje (2019). Millioner til forskning på hiv-medisin for kvinner. [Newspaper]. VG.
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Shaw, Alan; Hoffecker, Ian T.; Smyrlaki, Ioanna; Rosa, João; Grevys, Algirdas & Bryant-Bratlie, Diane Lynn [Show all 10 contributors for this article] (2019). Publisher Correction: Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies. Nature Nanotechnology. ISSN 1748-3387. 14(4), p. 398–398. doi: 10.1038/s41565-019-0404-3.
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Foss, Stian; Michaelsen, Terje Einar; Sandlie, Inger & Andersen, Jan Terje (2011). The Influence of Removal of the IgG Fab Arms on Binding to FcRn. Scandinavian Journal of Immunology. ISSN 0300-9475. 73(4), p. 350–351. doi: 10.1111/j.1365-3083.2011.02516.x.
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Andersen, JT; Daba, Muluneh B; Berntzen, G; Michaelsen, Terje Einar & Sandlie, I (2009). Cross-species binding analyses of mouse and human neonatal Fc receptor with their ligands. Implications for evaluations of therapeutic antibodies and albumin fusions.
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Tunheim, Gro; Kran, Anne-Marte Bakken; Rø, Gunnar Øyvind Isaksson; Hungnes, Olav; Lund-Johansen, Fridtjof & Tran, Trung [Show all 8 contributors for this article] (2020). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in late summer 2020. Folkehelseinstituttet. ISSN 978-82-8406-155-9. Show summary
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Tunheim, Gro; Kran, Anne-Marte Bakken; Rø, Gunnar Øyvind Isaksson; Steens, Anneke; Hungnes, Olav & Lund-Johansen, Fridtjof [Show all 9 contributors for this article] (2020). Seroprevalence of SARS-CoV-2 in the Norwegian population measured in residual sera collected in April/May 2020 and August 2019. Folkehelseinstituttet. ISSN 978-82-8406-109-2. Show summary
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Andersen, Jan Terje & Sandlie, Inger (2011). FcRn regulates the pharmacokinetics of albumin. Sojo University Publishing.
Published Jan. 22, 2018 9:57 AM
- Last modified May 5, 2020 2:38 PM