Lise Solberg Nes

• Graaf, Daniëlle L. van de; Lodder, Paul; Smeets, Tom; Lee, Marije L. van der; Trompetter, Hester R. & Schreurs, Karlein M. G. [Show all 9 contributors for this article] (2026). Embrace Pain-A Randomized Controlled Trial of Online Acceptance and Commitment Therapy for Painful Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors. Psycho-Oncology. ISSN 1057-9249. 35(9). doi: 10.1002/pon.70608. Full text in Research Archive Show summary

  Introduction Chemotherapy-induced peripheral neuropathy (CIPN) is a common and persistent side effect of chemotherapy, with up to 30% of patients reporting symptoms 6 months post-treatment. Painful CIPN can impair sleep, mood, and physical functioning. We evaluated “Embrace Pain,” an online Acceptance and Commitment Therapy (ACT) based self-help intervention that may be of support for cancer survivors with chronic painful CIPN. Methods The Embrace Pain Randomized Controlled Trial (RCT) compared ACT with a waiting list condition (WLC) using a two-armed randomized design. Adults (≥ 18 years) with painful CIPN ≥ 6 months post-chemotherapy were randomized to an 8-week guided online ACT program or WLC. Primary outcome was pain interference (Multidimensional Pain Inventory, MPI). Secondary outcomes included pain catastrophizing, psychological flexibility, CIPN severity, pain intensity, and quality of life (QoL). Linear mixed models and criteria for clinically significant change were used to evaluate outcomes from baseline to 3-month follow-up. Results 112 participants were included (57 ACT, 55 WLC). No significant treatment effect was observed for the primary outcome, pain interference, with ACT not outperforming the WLC over time. However, more ACT participants showed clinically significant improvement in pain interference at 3-month follow-up (47.4% vs. 23.6%) than WLC participants, and exploratory analyses showed greater reductions in pain catastrophizing in the ACT group. No between-group differences were found for psychological flexibility, CIPN severity, pain intensity, or QoL. Discussion Online ACT did not demonstrate a significant treatment effect on pain interference in those with painful CIPN. Exploratory findings suggest potential benefits for pain catastrophizing and clinically meaningful improvement in pain interference for some participants. Larger studies are needed to confirm these findings.

• Nes, Lise Solberg; Børøsund, Elin; Nordang, Elise Flakk; Asbjørnsen, Rikke Aune; Eide, Hilde & Varsi, Cecilie [Show all 15 contributors for this article] (2026). Delivery Model Matters for Digital Interventions in Pain Self-Management: Mixed Methods Study. Journal of Medical Internet Research (JMIR). ISSN 1439-4456. 28. doi: 10.2196/89780. Full text in Research Archive
• Varsi, Cecilie; Børøsund, Elin; Ehlers, Shawna L.; Clark, Matthew M.; Andrykowski, Michael A. & Nes, Lise Solberg (2026). Potential mechanisms within the digital stress-management intervention StressProffen for cancer survivors: a qualitative study post randomized controlled trial. Frontiers in Psychology. 16. doi: 10.3389/fpsyg.2025.1703540. Full text in Research Archive Show summary

  Background: Cancer diagnoses and treatment are characterized by physical and psychological stressors. Evidence-based psychosocial stress-management interventions offer physical and psychological relief, but are not always available. Results from clinical trials show the digital, evidence-based, and user-centered stress-management intervention StressProffen to be associated with reduced stress, anxiety, and depression, as well as improved self-regulatory capacity and quality of life for cancer survivors. While such interventions can be efficacious, the actual mechanisms of these effects remain understudied. Objective: To qualitatively explore potential mechanisms in terms of psychological and behavioral change for cancer survivors after 12 months of access to StressProffen. Methods: Using a selection matrix to ensure variation in sex, age, diagnosis, and program progress, the current study invited 39 participants who had access to StressProffen over 12 months through a randomized controlled trial (RCT) to participate in post-RCT semi-structured qualitative interviews related to use and potential benefit. Interview transcripts were analyzed using thematic analysis. Results: Twenty-six cancer survivors completing the RCT agreed to participate. Qualitative analyses yielded five themes based upon patient-reported changes attributed to StressProffen use: (1) Self-awareness and personal values; who I am and what I want; (2) Comprehension; reflection and understanding of difficult thoughts and emotions; (3) Social relationships; manage my relations, (4) Relaxation and focusing skills; learn new relaxation, distraction, and focusing techniques; and (5) Coping skills and adjustment; coping with, adjusting to, and being prepared for difficult situations in all aspects of life. Conclusion: Access to digital stress-management interventions, such as StressProffen, has been shown to contribute to improved psychological wellbeing and quality of life for cancer survivors. Qualitative analyses of patient-reported benefits suggest mechanisms of enhanced self-awareness, improved comprehension of the relationship between thoughts and emotions, stronger social relationships, and improved skill self-efficacy in terms of relaxation, focusing, and coping skills. A mixed methods approach, including quantitative as well as qualitative analyses, can facilitate in-depth explorations of the impact of digital psychosocial interventions for cancer survivors.

• Watland, Solbjørg; Nes, Lise Solberg; Ekeberg, Øivind; Rostrup, Morten; Hanson, Elizabeth & Ekstedt, Mirjam [Show all 8 contributors for this article] (2025). Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial. Intensive Care Medicine. ISSN 0342-4642. 51(11), p. 2042–2053. doi: 10.1007/s00134-025-08139-x. Full text in Research Archive Show summary

  Purpose: A long-term evaluation of The Caregiver Pathway, a model to follow up family caregivers on Post-intensive Care Symptoms among Family (PICS-F). Methods: A single-center non-blinded randomized controlled trial including 196 family caregivers to critically ill patients randomized to intervention (n = 101) or control group (n = 95). The Caregiver Pathway intervention consists of: (1) a digital assessment followed by a conversation with a nurse in the first days at the ICU, (2) a supportive card when leaving the ICU, (3) an offer to receive a phone call following patient transfer to a step-down unit, and (4) a followup conversation within 3 months after discharge. Outcome measures were collected at 6 and 12 months, including symptoms of post-traumatic stress disorder (PTSD), anxiety, depression, Health-related Quality of Life (HRQoL), hope,and self-efficacy. Results: The Caregiver Pathway was associated with a significant effect for symptoms of PTSD after 6 months compared with controls, mean IES-R score: 25.8 [95% CI 21.9–29.7] versus 30.9 [95% CI 26.7–35.0], p = 0.009, and a trend toward an effect after 12 months: IES-R score: 25.0 [95% CI 21.3–28.7] versus 28.4 [95% CI 24.1–32.7], p = 0.057. Subgroup analyses at 12 months showed a significant intervention effect among family caregivers of patients who survived compared to controls for PTSD, IES-R score: 19.8 [95% CI 15.3–24.2] versus 29.1 [95% CI 23.5–34.6], p = 0.001, and anxiety, HADS-A score: 4.3 [95% CI 3.1–5.4] versus 6.8 [95% CI 5.2–8.4], p = 0.003. Conclusions: The Caregiver Pathway has the potential to reduce the symptoms of PICS-F, especially among family caregivers whose patient has survived.

• Svendsen, Karianne; Nes, Lise Solberg; Leithe, Sigrid; Meland, Anders; Gjelsvik, Ylva Maria & Børøsund, Elin [Show all 17 contributors for this article] (2025). Testing two digital stress-management interventions in a randomized controlled trial of breast cancer patients. Scientific Reports. 15, p. 1–16. doi: 10.1038/s41598-025-22889-0. Full text in Research Archive Show summary

  Abstract The digital stress-management intervention StressProffen has been shown to be associated with improved well-being and quality of life for cancer survivors. In the Coping After Breast Cancer (CABC) trial, effects of 6 months’ access to modified versions of StressProffen, delivered through a digital download-only model, were examined. Women with breast cancer were invited to participate in the trial 6–9 months following diagnosis. Eligible participants were randomized to either: (1) digital cognitive behavioral therapy stress-management intervention (CBI), n  = 140, (2) digital mindfulness-based stress-management intervention (MBI), n  = 143, or (3) usual-care (control group), n  = 147. Primary outcome was change in perceived stress level (PSS-10), while secondary outcomes included changes in health-related quality of life (HRQoL), anxiety and depression, fatigue, mindfulness, sleep and coping. Perceived stress level at baseline was low for all groups. No statistically significant mean differences (MD) were detected between either of the intervention groups and the control group from baseline to 6-month follow-up for perceived stress level (MBI: MD -0.28 [95%CI: -1.75, 1.19], CBI: MD -0.42 [95%CI: -1.89, 1.06]), nor for the majority of the secondary outcomes. After 6 months of access, the CBI and MBI stress-management interventions did not yield significantly improved outcomes for women with breast cancer compared with usual-care controls. Further explorations of which interventions and delivery models may optimize use and effect, best timing for delivery, and individual preferences are needed. ClinicalTrials.gov identifier NCT04480203.

• Strand, Elin Bolle; Varsi, Cecilie; Børøsund, Elin; Eide, Hilde; Schreurs, Karlein M. G. & Waxenberg, Lori B. [Show all 12 contributors for this article] (2025). Changes in cognition, coping, pain and emotions after 12-months access to the digital self-management program EPIO. Frontiers in Psychology. 16. doi: 10.3389/fpsyg.2025.1540852. Full text in Research Archive Show summary

  Background: Psychosocial pain self-management interventions can be of support for people living with chronic pain. Since psychosocial support is not always accessible, digital health interventions may increase outreach of these types of evidence-based interventions. Objectives: To explore participants' experiences from 12-month access to the digital pain self-management program EPIO, particularly in terms of any behavioral and/or psychological changes experienced. Methods: Participants (N = 25) engaged in individual semi-structured interviews following 12-month access to the EPIO intervention. Qualitative thematic analyses were conducted seeking to identify any behavioral and/or psychological changes experienced through intervention use, and what contributed to these changes. Results: Participants were predominantly women (72%), median age 46 (range 26–70), with a range of self-reported pain conditions and the majority reporting pain duration >10 years (64%). Analyses identified three main themes and subsequent sub-themes: (1) Changes in Cognition; insight and self-awareness, acceptance and shifting focus, (2) Changes in Coping; pain, emotions, and activity pacing, and (3) Content and Functionality Specific Engagement; breathing and other mind-body exercises, thought-reflection exercises, and functionalities. Conclusions: People with chronic pain experienced positive behavioral and/or psychological changes in terms of cognition and coping after 12 months access to the EPIO digital pain self-management program. The most prominent changes included increased understanding of the connection between own thoughts, feelings, and behavior, gaining concrete strategies to cope with everyday life living with pain, and utilizing these strategies to reduce pain and interference of pain, as well as to improve emotion regulation and psychological wellbeing.

• Svendsen, Karianne; Leithe, Sigrid; Trewin-Nybråten, Cassia Bree; Balto, Aina; Nes, Lise Solberg & Meland, Anders [Show all 12 contributors for this article] (2024). How Did Breast Cancer Patients Fare during Different Phases of the COVID-19 Pandemic in Norway Compared to Age-Matched Controls? Cancers. 16(3). doi: 10.3390/cancers16030602. Full text in Research Archive Show summary

  Little is known about how health-related quality of life (HRQoL) in breast cancer cases differed from that of controls during and after the COVID-19 pandemic. This study used data from an ongoing, nationwide HRQoL survey of 4279 newly diagnosed breast cancer cases and 2911 controls to investigate how breast cancer patients fared during different phases of the pandemic compared to controls. Responders during 2020–2022 were categorized into three COVID-19-related phases: the social restrictions phase, the high infection rate phase, and the post-pandemic phase. Across phases, breast cancer cases had significantly worse scores in most HRQoL domains compared to controls. Apart from slightly more insomnia in the high infection rate phase for both cases and controls, and better social functioning for young cases in the post-COVID-19 phase, the case-control differences in HRQoL remained consistent across phases. When the phases were assessed as one period, young women and those living with children

• Asbjørnsen, Rikke Aune; Børøsund, Elin; Hjelmesæth, Jøran Sture; Smedsrød, Mirjam Lien; Ollivier, Marianne & Wentzel, Jobke [Show all 9 contributors for this article] (2024). Digital behaviour change intervention for weight loss maintenance in adults with obesity: a feasibility pilot study of eCHANGE. Behaviour and Information Technology. ISSN 0144-929X. p. 1–19. doi: 10.1080/0144929X.2024.2399299. Full text in Research Archive Show summary

  Successful weight maintenance after weight loss is challenging. Digital interventions may facilitate behaviour change to prevent weight regain, however little is known about the acceptance and use of digital interventions in support of weight maintenance. This mixed methods study aims to evaluate user experiences, system use, and preliminary efficacy of eCHANGE, an application based self-management intervention for weight loss maintenance. A 3-month multi-site single group feasibility pilot study was conducted among adults (N = 60) with BMI ≥30 kg/m2, aiming to maintain weight after weight loss of ≥8%. User experiences and system use were examined through validated questionnaires, system use log data, and individual interviews (n = 15). Preliminary efficacy testing included body weight and patient reported outcome measures. Participants rated eCHANGE usability and usefulness as good in support of weight maintenance, with variation in usage. Analysis indicated that higher behavioural engagement scores were statistically significantly associated with frequency of technology usage. Weight loss was maintained by 83% of the participants at 3-months (i.e. defined as weight change of <3% of baseline body weight (kg)). Digital interventions, combining persuasive system design principles and behaviour change techniques, supporting self-regulation and maintenance of health behaviours, have the potential to facilitate weight maintenance after weight loss.

• Watland, Solbjørg; Nes, Lise Solberg; Ekeberg, Øivind; Rostrup, Morten; Hanson, Elizabeth & Ekstedt, Mirjam [Show all 9 contributors for this article] (2024). The Caregiver Pathway Intervention Can Contribute to Reduced Post-Intensive Care Syndrome Among Family Caregivers of ICU Survivors: A Randomized Controlled Trial. Critical Care Medicine. ISSN 0090-3493. 53(3), p. 1–12. doi: 10.1097/CCM.0000000000006546. Full text in Research Archive Show summary

  OBJECTIVES: Explore short-term effects of “The Caregiver Pathway,” an inter- vention for family caregiver follow-up, on Post-Intensive Care Syndrome symp- toms among families (PICS-F). DESIGN: A randomized controlled trial. SETTING: A medical ICU at a Norwegian University Hospital. PARTICIPANTS: One hundred ninety-six family caregivers of critically ill patients randomized to an intervention (n = 101) or control group (n = 95). INTERVENTIONS: “The Caregiver Pathway” four-step model offers individual and structured follow-up, including: 1) mapping family caregivers’ needs and con- cerns with an assessment tool followed by a conversation with an ICU nurse within the first days at the ICU, 2) a supportive card when leaving the ICU, 3) offer for the family caregivers to receive a phone call after ICU patient discharge, and 4) a follow-up conversation within 3 months. MEASUREMENTS AND MAIN RESULTS: Data were collected at baseline and after 3 months and analyzed using linear regression. No significant effects were detected when comparing all participants completing 3-month outcome measurements (n = 144). A subgroups analysis stratified on patient survival, how- ever, showed statistically significant effect for family caregivers of patients surviv- ing the ICU stay receiving the intervention compared with controls. Caregivers of surviving patients reported improved symptoms related to post-traumatic stress disorder, measured by Impact of Event Scale-Revised (B = –8.2 [95% CI, –14.2 to –2.2]; p = 0.008), anxiety (B = –2.2 [95% CI, –4.0 to –0.5]; p = 0.014), and depression (B = –1.5 [95% CI, –2.9 to –0.1]; p = 0.035); measured by the Hospital Anxiety and Depression Scale, subscore physical functioning in health- related quality of life (B = 9.7 [95% CI, 0.3–19.0]; p = 0.043); measured by Short Form 12-Item Health Survey; and hope (B = 2.4 [95% CI, 0.4–4.3]; p = 0.017) and measured by the Herth Hope Index. At 3-month, the model did not appear to improve the outcomes for family caregivers of nonsurviving patients. CONCLUSIONS: “The Caregiver Pathway” intervention was associated with reduced symptoms of PICS-F in family caregivers of surviving ICU patients com- pared with controls.

• Strand, Elin Bolle; Nes, Lise Solberg; Børøsund, Elin; Pripp, Are Hugo; Malarkey, William & Dammen, Toril (2024). Psychometric properties of the REMAP resilience scale in a Norwegian sample of ME/CFS patients and healthy controls. Psychological Test Adaptation and Development (PTAD). 5(1), p. 163–174. doi: 10.1027/2698-1866/a000076. Full text in Research Archive Show summary

  Being able to increase and know how to strengthen resilience may be relevant for patients living with long-term symptoms such as chronic fatigue syndromes. The current study aimed to examine the psychometric properties of a Norwegian-translated version of the REMAP resilience measure in a sample of patients with myalgic encephalomyelitis/chronic fatigue syndrome and healthy controls. Factor analyses indicated poor fit for both the one- and five-factor solutions of the translated REMAP measure with best fit for a correlated five-factor model. Validity proved to be good, while reliability was poor for two of the subscales. Differences were revealed between gender, age groups, and between patients and healthy controls. The construct validity indicates that REMAP assesses adequate aspects of resilience. REMAP might be valuable to use to show that resilience resources could be developed in various life domains and aid in coping with chronic illness. However, REMAP should be further tested in other samples and cultures.

• Nes, Lise Solberg; Børøsund, Elin; Varsi, Cecilie; Eide, Hilde; Waxenberg, Lori B. & Weiss, Karen E. [Show all 14 contributors for this article] (2024). Living well with chronic pain: a 12-month randomized controlled trial revealing impact from the digital pain self-management program EPIO. Pain Reports. 9(4), p. 1–12. doi: 10.1097/PR9.0000000000001174. Full text in Research Archive Show summary

  Introduction: Chronic pain affects a wide range of physical and psychological aspects of life for those impacted. Psychosocial treatment approaches may be of support, but outreach is still limited. Objectives: To evaluate the efficacy of EPIO, an evidence-informed, user-centered digital self-management intervention for people with chronic pain, in a 12-month randomized controlled trial. Methods: People living with chronic pain (N 5 266) were randomized to the EPIO intervention (n 5 132) or a usual-care control group (n 5 134). The intervention was delivered in a simple blended care model, and outcome measures collected at baseline, 6 months, and 12 months. Generalized linear models for repeated measures were fitted to compare groups over time. Results: Participants were primarily female (81%), median age 49 years (range 22–78), with heterogeneous pain conditions, and had lived with pain .5 years (77.6%). A mixed linear model with all timepoints included revealed no statistically significant group differences for the primary outcome of pain interference. Significant psychological benefits in favor of the intervention group were however detected for depression (P 5 0.022), self-regulatory fatigue (P 5 0.024), vitality (P 5 0.016), and mental health (P 5 0.047). Baseline to 12-month changes showed additional favorable effects for anxiety (between-group mean differences [MDs] 5 0.79, P 5 0.047), depression (MD 5 1.08, P 5 0.004), self-regulatory fatigue (MD 5 2.42, P 5 0.021), pain catastrophizing (MD 5 2.62, P 5 0.009), and health-related quality of life. Conclusions: The EPIO program aims to improve outreach of evidence-based pain self-management interventions. Findings demonstrate how using EPIO can lead to sustainable psychological change, enhancing mental health and health-related quality of life for people suffering from pain, providing a chance to live well with the pain

• Asbjørnsen, Rikke Aune; Hjelmesæth, Jøran Sture; Smedsrød, Mirjam Lien; Wentzel, Jobke; Clarke, Matthew & Kelders, Saskia M. [Show all 8 contributors for this article] (2024). Implementation of a Digital Behavior Change Intervention (eCHANGE) for Weight Loss Maintenance Support: A Service Design and Technology Transfer Approach. Frontiers in Digital Health. 6. doi: 10.3389/fdgth.2024.1394599. Full text in Research Archive Show summary

  Obesity is a chronic disease, and while weight loss is achievable, long-term weight loss maintenance is difficult and relapse common for people living with obesity. Aiming to meet the need for innovative approaches, digital behavior change interventions show promise in supporting health behavior change to maintain weight after initial weight loss. Implementation of such interventions should however be part of the design and development processes from project initiation to facilitate uptake and impact. Based on the development and implementation process of eCHANGE, an evidence-informed application-based self-management intervention for weight loss maintenance, this manuscript provides suggestions and guidance into; (1) How a service design approach can be used from initiation to implementation of digital interventions, and (2) How a technology transfer process can accelerate implementation of research-based innovation from idea to market.

• Bøhn, Synne-Kristin Hoffart; Svendsen, Karianne; Balto, Aina; Gjelsvik, Ylva Maria; Myklebust, Tor Åge & Børøsund, Elin [Show all 13 contributors for this article] (2024). Health-related quality of life among women diagnosed with in situ or invasive breast cancer and age-matched controls: a population-based study. Journal of Patient-Reported Outcomes. 8(1). doi: 10.1186/s41687-024-00781-1. Full text in Research Archive Show summary

  Purpose: A breast cancer (BC) diagnosis may negatively affect health-related quality of life (HRQoL). However, there are few comparisons of HRQoL at several time points for women with BC, and particular when subdivided into invasive and in situ tumors. The purpose of this study was to investigate various aspects of HRQoL in women recently diagnosed with invasive BC or ductal carcinoma in situ (in situ) compared to age-matched BC free controls in a population-wide sample recruited through the Cancer Registry of Norway. Methods: This cross-sectional study utilized HRQoL data collected in 2020–2022 from a digital survey including 4117 cases (3867 women with invasive BC and 430 with in situ) and 2911 controls. HRQoL was assessed ≥ 21 days after diagnosis, using EORTC QLQ-C30. This includes scores assessing global quality of life (gHRQoL) and HRQoL functions and symptoms. Multivariable regression analyses were used to compare HRQoL between cases and controls and to identify factors associated with gHRQoL and fatigue. Additionally, HRQoL 14 months after diagnosis was analyzed in 1989 of the included cases and in 1212 of the controls. Score differences of ≥ 10 points were considered clinically relevant and thus presented in the results. Results: Invasive BC cases had lower gHRQoL, role- and social functioning in addition to more fatigue than controls. In situ cases had lower role—and social functioning than controls. Invasive BC cases scored worse than in situ on all domains, but the differences were not considered clinically relevant. Physical activity was associated with better gHRQoL and less fatigue in invasive BC, in situ and controls. Both invasive BC and in situ cases improved their role- and social functioning scores from diagnosis to 14 months follow-up, however no improvement was seen for fatigue. Conclusion: Women with invasive BC and in situ reported lower role- and social functioning scores than controls right after diagnosis with improvements 14 months after diagnosis. Physical activity was associated with better gHRQoL and less fatigue and should, whenever possible, play a key role in the care for BC patients.

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• Hoksnes, Christine Marie Rygg; Børøsund, Elin & Nes, Lise Solberg (2026). StressProffen Helsepersonell. Full text in Research Archive
• Hoksnes, Christine Marie Rygg; Børøsund, Elin & Nes, Lise Solberg (2026). Stressmestring for helsepersonell - Resultat fra en kvasieksperimentell studie med den digitale stressmestringsintervensjonen StressProffen. Full text in Research Archive
• Hoksnes, Christine Marie Rygg; Børøsund, Elin & Nes, Lise Solberg (2026). Stressmestring for helsepersonell - Resultat fra en kvasieksperimentell studie med den digitale stressmestringsintervensjonen StressProffen. Full text in Research Archive
• Østerås, Nina; Tveter, Anne Therese & Nes, Lise Solberg (2026). Apper på resept – har vi råd til å la være? Full text in Research Archive Show summary

  Så lenge det er mer lønnsomt å kalle inn enn å forebygge gjennom å støtte egenbehandling hjemme, vil digitalisering forbli et ideal, ikke en realitet.

• Nes, Lise Solberg (2026). Digital Stress-Management in Cancer – Optimizing Outreach and Impact. Full text in Research Archive
• Nes, Lise Solberg (2026). Digital Health Interventions & Artificial Intelligence (AI) – Opportunities and Need for Caution. Full text in Research Archive
• Nes, Lise Solberg (2026). Optimalization X – project initiation summary. Full text in Research Archive
• Watland, Solbjørg; Børøsund, Elin & Nes, Lise Solberg (2026). Pårørende, med fokus på hele familien. Full text in Research Archive
• Nes, Lise Solberg (2026). Artificial Intelligence – Grounds for Caution. Full text in Research Archive
• Asbjørnsen, Rikke Aune; Hjelmesæth, Jøran Sture; Ollivier, Marianne; Johnson, Line Kristin; Hertel, Jens Kristoffer & Nes, Lise Solberg (2026). Initiating the eBATTLE Obesity Project: User-Centered Design of a Digital Intervention to Support Healthy Lifestyle and Weight Management in Adolescents with Obesity. doi: 10.1093/abm/kaag012. Full text in Research Archive
• Børøsund, Elin; Hagen, Milada; Varsi, Cecilie; Eide, Hilde; Waxenberg, Lori B. & Weiss, Karen E. [Show all 14 contributors for this article] (2026). Exploring models for delivery of the digital pain self‑management program EPIO. doi: 10.1093/abm/kaag012. Full text in Research Archive
• Børøsund, Elin; Ehlers, Shawna L.; Clark, Matthew M.; Andrykowski, Michael & Nes, Lise Solberg (2026). What do cancer survivors want from a digital stress management application? doi: 10.1002/pon.70380. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Individual and Structured Follow-Up of family caregivers of Intensive Care Patients: The Caregiver Pathway. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). The Caregiver Pathway – a follow-up model to reduce Post Intensive Care Symptoms - Families (PICS-F). Full text in Research Archive
• Børøsund, Elin & Nes, Lise Solberg (2025). Digital stress management program for cancer patients: Introduction to StressProffen and results from a 12-month RCT. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Supporting Children as family caregivers and their families in the Intensive Care Unit. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Hvordan gjennomføre kvantitative studier. Full text in Research Archive
• Nes, Lise Solberg (2025). How to motivate for increased use of digital solutions post research study. Full text in Research Archive
• Nes, Lise Solberg; Nordang, Elise Flakk; Torgersen, Gudrun Kristin & Ollivier, Marianne (2025). Heart-Check – a collaborative project. Full text in Research Archive
• Strand, Elin Bolle; Varsi, Cecilie; Børøsund, Elin & Nes, Lise Solberg (2025). Effect and Experiences with the Digital Self-management Program EPIO. The 7th International Congress on Controversies Fibromyalgia. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital self-management solutions for patients and health care providers. Better at work – increased time for clinical and scientific work. Full text in Research Archive
• Børøsund, Elin & Nes, Lise Solberg (2025). Digital solutions for communication and self-management support. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Ivaretakelse av pårørende. Full text in Research Archive
• Nes, Lise Solberg (2025). Workshop – Digital pain management for rare, hereditary connective tissue diseases with aortopati – a feasibility consideration in cardiac rehabilitation. Full text in Research Archive
• Asbjørnsen, Rikke Aune; Børøsund, Elin; Hjelmesæth, Jøran Sture; Smedsrød, Mirjam Lien; Ollivier, Marianne & Wentzel, Jobke [Show all 9 contributors for this article] (2025). Approaches from idea to implementation of eHealth innovations in healthcare: Experiences and perspectives from an eHealth innovation seeking to support behavior change after weight loss. Full text in Research Archive
• Nes, Lise Solberg; Børøsund, Elin; Hoksnes, Christine Marie Rygg; Bacolod, Maria Estefan Coloma & Torgersen, Gudrun (2025). Stress, Cognitive Behavioral Therapy and StressProffen. Full text in Research Archive
• Børøsund, Elin & Nes, Lise Solberg (2025). Department of Digital Health Research – Knowledge and Solutions Creating Better Health. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital Research-based Self-management Solutions for Patients and Health Care Providers. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Ivaretakelse av pårørende og pårørendetilfredshet på MI. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Pårørende til intensivpasienter - individuell oppfølging -funn fra studie og implementeringsarbeid ved Medisinsk Intensiv. Full text in Research Archive
• Ollivier, Marianne; Asbjørnsen, Rikke Aune & Nes, Lise Solberg (2025). Opplæring helsepersonell eMAMMO – RCT. Full text in Research Archive
• Nes, Lise Solberg (2025). Summary EVALMEDHELSE departmental report findings. Full text in Research Archive
• Nes, Lise Solberg (2025). Feedback and SWOT processes – EVALMEDHELSE. Full text in Research Archive
• Nes, Lise Solberg & Hoksnes, Christine Marie Rygg (2025). SWOT analysis Department of Digital Health Research. Full text in Research Archive
• Nes, Lise Solberg; Hoksnes, Christine Marie Rygg & Ollivier, Marianne (2025). Evaluation and the Road Ahead (EVALMEDHELSE). Full text in Research Archive
• Nes, Lise Solberg; Børøsund, Elin; Varsi, Cecilie; Eide, Hilde; Kristjansdottir, Olöf Birna & Waxenberg, Lori B. [Show all 16 contributors for this article] (2025). Digital Pain Self-Management with EPIO: Design, Development, Evaluation - and Future Directions. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital self-management solutions: Something for healthcare providers to offer – and use. Full text in Research Archive
• Nes, Lise Solberg (2025). Annual Summary Digital Health Research. Full text in Research Archive
• Nordang, Elise Flakk; Torgersen, Gudrun Kristin; Ollivier, Marianne & Nes, Lise Solberg (2025). Hjerte-sjekken. Full text in Research Archive
• Nes, Lise Solberg (2025). What can be done to motivate people to use digital solutions after research study completion. Full text in Research Archive
• Nes, Lise Solberg; Nordang, Elise Flakk; Torgersen, Gudrun Kristin & Ollivier, Marianne (2025). Heart Check - a collaborative project. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Implementering av MI-modellen. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). 12 måneders resultat Pårørendestudie. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Implementering av MI-modellen. Full text in Research Archive
• Watland, Solbjørg; Børøsund, Elin; Nes, Lise Solberg & Strand, Elin Bolle (2025). Hvordan gjennomføre kvantitative studier. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital Research-based Self-management Solutions for Patients and Healthcare Providers. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Ivaretakelse av pårørende og pårørendetilfredshet på MI. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Pårørende til intesivpasienter - individuell oppfølging -funn fra studie og implementeringsarbeid ved Medisinsk Intensiv. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital self-management solutions for patients and health care providers. Better at work – increased time for clinical and scientific work. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital Stress-Management in Cancer: Optimizing Outreach and Impact - A Proposal. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). PICS-F Hva kan vi gjøre for å redusere det? Resultater fra en RCT. Full text in Research Archive
• Nes, Lise Solberg (2025). Digital Health Research and EPIO. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2025). Ivaretakelse av pårørende. Full text in Research Archive
• Nes, Lise Solberg; Børøsund, Elin; Rygg, Christine Marie; Bacolod, Maria Estefan Coloma & Torgersen, Gudrun Kristin (2025). Stress, kognitiv adferdsterapi og StressProffen. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2024). Pårørende til kritisk syke. Full text in Research Archive
• Nes, Lise Solberg; Børøsund, Elin; Varsi, Cecilie; Eide, Hilde; Waxenberg, Lori B. & Weiss, Karen Elizabeth [Show all 14 contributors for this article] (2024). Results from a One-Year Randomized Controlled Trial with the Digital Pain Self-management Intervention EPIO. Full text in Research Archive
• Strand, Elin Bolle; Nes, Lise Solberg; Børøsund, Elin; Eide, Hilde; Kristjansdottir, Olöf Birna & Schreurs, Karlein MG [Show all 14 contributors for this article] (2024). Participants’ experiences after using the EPIO pain self-management program – a qualitative study EAPM European association of psychosomatic medicine. Full text in Research Archive
• Børøsund, Elin; Nes, Lise Solberg; Rygg, Christine Marie & Bacolod, Maria Estefan Coloma (2024). StressProffen. Utvikling, testing og implementering av et digitalt app-basert program for stressmestring. Full text in Research Archive
• Nes, Lise Solberg (2024). Annual Summary Digital Health Research 2024. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2024). MI-modellen, en modell for å ivareta pårørende til kritisk syke. Full text in Research Archive
• Strand, Elin Bolle; Nes, Lise Solberg; Børøsund, Elin; Bostrøm, Katrine; Eide, Hilde & Varsi, Cecilie [Show all 15 contributors for this article] (2024). Det app-baserte smertemestringsprogrammet EPIO – resultater og status. Full text in Research Archive
• Nes, Lise Solberg (2024). Research and Innovation by the Department of Digital Health Research. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2024). Pårørende. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2024). Pårørende til kritisk syke - Veien videre. Full text in Research Archive
• Strand, Elin Bolle; Nes, Lise Solberg; Børøsund, Elin; Eide, Hilde; Kristjansdottir, Olöf Birna & Schreurs, Karlein M. G. [Show all 14 contributors for this article] (2024). Participants’ experiences after using the EPIO pain self-management program – a qualitative study. Full text in Research Archive
• Asbjørnsen, Rikke Aune; Børøsund, Elin; Hjelmesæth, Jøran Sture; Smedsrød, Mirjam Lien; Ollivier, Marianne & Clark, Matthew [Show all 9 contributors for this article] (2024). System Use Findings from a Pilot Trial with the Digital Weight Loss Maintenance Intervention eCHANGE. Full text in Research Archive
• Nes, Lise Solberg (2024). Research Based Health Applications. Full text in Research Archive
• Nes, Lise Solberg; Børøsund, Elin; Varsi, Cecilie; Kristjansdottir, Olöf Birna; Schreurs, Karlein MG & Waxenberg, Lori B. [Show all 12 contributors for this article] (2024). EPIO©™ Et digitalt støtteprogram for de som lever med langvarige smerter. Full text in Research Archive
• Strand, Elin Bolle; Nes, Lise Solberg; Børøsund, Elin; Varsi, Cecilie; Kristjansdottir, Olöf Birna & Schreurs, Karlein M.G. [Show all 14 contributors for this article] (2024). EPIO - et digitalt støtteprogram for de som lever med langvarige smerter: Metoder og resultater. Full text in Research Archive
• Børøsund, Elin; Nes, Lise Solberg & Rygg, Christine Marie (2024). StressProffen - Digital stressmesting for pasienter med kreft. Full text in Research Archive
• Nes, Lise Solberg; Børøsund, Elin; Varsi, Cecilie; Eide, Hilde; Waxenberg, Lori & Weiss, Karen E. [Show all 13 contributors for this article] (2024). Results from a one-year randomized controlled trial with the digital pain self-management intervention EPIO. Annals of Behavioral Medicine. ISSN 0883-6612. doi: 10.1093/abm/kaae014. Full text in Research Archive
• Ollivier, Marianne; Søiland, Nora Bergem; Hertel, Jens Kristoffer; Hjelmesæth, Jøran Sture; Asbjørnsen, Rikke Aune & Johnson, Line Kristin [Show all 7 contributors for this article] (2024). Presentasjon av Habition. Full text in Research Archive
• Nes, Lise Solberg (2024). How can self-help solutions contribute to better health? Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg; Hanson, Elizabeth; Ekstedt, Mirjam; Stenberg, Una & Børøsund, Elin (2024). Pårørende til kritisk syke - Veien videre. Full text in Research Archive
• Lie, Irene; Røkeness, Sandra; Skredsvik, Kari; Johannsen, Nis; lindsjørn, knut erik & Hasle, Camilla holth [Show all 7 contributors for this article] (2024). Healthcare professionals' experiences of the usefulness and ease of using a digital medical translation tool in communicating with minority language-speaking hospitalized heart surgery patients. Full text in Research Archive
• Lie, Irene; Røkeness, Sandra; Skredsvig, Kari; Johannsen, Nis; lindsjørn, knut erik & Hasle, Camilla holth [Show all 7 contributors for this article] (2024). Importance of key stakeholder communication in the implementation of an in-hospital digital medical translation application for heart surgery patients: a qualitative study. Full text in Research Archive
• Watland, Solbjørg; Nes, Lise Solberg & Børøsund, Elin (2024). MI modellen: en modell for oppfølging av pårørende kan bidra til reduserte symptomer på PICS-F, 3 måneder resultater. Full text in Research Archive
• Nes, Lise Solberg; Nordang, Elise Flakk & Torgersen, Gudrun Kristin (2024). Heart-Check: A collaboration between the Department of Cardiology and the Department of Digital Health Research. Full text in Research Archive
• Børøsund, Elin; Varsi, Cecilie; Ehlers, Shawna L.; Clark, Matthew; Andrykowski, Michael A & Nes, Lise Solberg (2024). How a Digital Stress-Management Intervention can Contribute to Psychosocial Well-being and Health-Related Quality of Life: A Qualitative Study. Full text in Research Archive
• Svendsen, Karianne; Leithe, Sigrid; Myklebust, Tor Åge; Eriksen, Hege Randi; Meland, Anders & Nes, Lise Solberg [Show all 8 contributors for this article] (2024). Associations between lifestyle factors and health-related quality of life in breast cancer patients and controls. Norsk tidsskrift for ernæring (NTFE). ISSN 1503-5034. 22(5), p. 89–89. doi: 10.18261/ntfe.22.5.127. Full text in Research Archive
• Børøsund, Elin; Nes, Lise Solberg; Rygg, Christine Marie & Bacolod, Maria Estefan Coloma (2024). StressProffen – et digitalt stressmestringsprogram for pasienter med kreft. Full text in Research Archive
• Nes, Lise Solberg (2024). Implementation and use challenges post research. Full text in Research Archive
• Nes, Lise Solberg (2024). Organizational and professional roles in management and academia. Full text in Research Archive
• Nes, Lise Solberg (2024). Accessibility of evidence-based digital solutions - a necessity. In session: Mental health - How to prevent illness. Full text in Research Archive
• Nes, Lise Solberg (2024). Digital Solutions for Self-Management. Full text in Research Archive
• Børøsund, Elin; Nes, Lise Solberg; Varsi, Cecilie & Seljelid, Berit (2024). Development and evaluation of a digital patient-provider communication intervention to facilitate shared decision making in chronic health care settings: InvolveMe. Universitetet i Oslo. ISSN 9788234803987. Full text in Research Archive Show summary

  Living with chronic health conditions often imply symptoms that negatively affect health-related quality of life. Effective symptom management necessitates understanding and addressing patient symptoms, needs, and preferences, yet identifying these can be challenging for both patients and health care providers. Unaddressed symptoms can exacerbate condition and lead to unnecessary suffering. Despite the potential benefits, widespread adoption of digital interventions in specialist health care services remains limited. This dissertation aimed to develop and evaluate a digital patient-provider communication intervention, InvolveMe, focusing on non-functioning pituitary adenoma and renal transplant recipients. Through an exploratory research design guided by the United Kingdom's Medical Research Council framework for complex intervention, studies exploring patient and provider perspectives were conducted through interviews, focus groups, workshops, project steering group committee meetings, system log data and a feasibility pilot study. Findings revealed insights into challenges experienced by patients, which informed the development of InvolveMe's content and system; a symptom- and needs assessment and access to secure messaging. By identifying potential facilitators and barriers, the intervention was tailored to the local context and key aspects for an implementation plan were highlighted. The feasibility pilot demonstrated InvolveMe to be a user-friendly and feasible intervention, where use of symptom- and needs assessment and secure messaging worked well, thus supporting shared decision making. Overall, this dissertation contributes to understanding how tailored interventions like InvolveMe, can provide insights into patients' challenges, preferences and facilitate shared decision making, enhancing chronic care.

• Bostrøm, Katrine & Nes, Lise Solberg (2024). A Mixed Methods Evaluation of EPIO; a Digital Pain Self-management Program for People Living with Chronic Pain. Universitetet i Oslo. ISSN 9788234803222. Full text in Research Archive Show summary

  Chronic pain is a disabling and distressing health concern that burdens patients, their loved ones, and society at large. To address the complexities of chronic pain, multidisciplinary pain management, including patient education and self-management interventions, has been recommended. The challenge is that in-person interventions are not always available for these patients. Digital solutions may improve access to such support, although knowledge about the use, engagement, and effect of existing digital pain management programs is still limited. The primary objective of this dissertation was to evaluate the feasibility, engagement, and short-term efficacy of EPIO, a digital pain self-management program for people with chronic pain. The mixed methods evaluation showed that the EPIO intervention was feasible and had excellent user satisfaction. The EPIO program fostered joy and enthusiasm, raised self-awareness, and a sense of acceptance and support in coping with pain. The results after three months in a randomized control trial showed statistically significant reductions in symptoms of depression and self-regulatory fatigue for the group using EPIO. Overall, digital interventions such as EPIO can be an essential step towards offering easy access to meaningful and effective digital pain self-management interventions and contribute to raising awareness and acceptance, helping improve psychological well-being for people with chronic pain.

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