Marius Trøseid

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Visiting address Sognsvannsveien 20 OUS Rikshospitalet 0372 Oslo
Postal address Postboks 4950 Nydalen OUS, Rikshospitalet 0424 Oslo

 

About

Associate professor Marius Trøseid is a senior consultant in infectious diseases and clinical immunology at Oslo University Hospital, and is leading a national research network on clinical microbiota science (www.microbiota.no). I this environment, we have developed an in house sequencing-based microbiota-profiling pipeline including bioinformatics and applied it in multiple conditions and study designs, including RCTs in chronic infections and inflammatory diseases. Trøseid has been involved in several RCTs as PI or co-PI, including interventions with statins, probiotics, antibiotics and life style interventions. 

Ongoing projects

Ongoing projects include CoMicS (Copenhagen-Oslo HIV Comorbidity and Microbiota Study), the largest microbiota study in HIV-infected individuals to date, the EU funded SCRATCH consortium (Microbiota-based SCReening of Anal Cancer in HIV-infected individuals), and the recently finalized first-in-man multi center RCT of gut microbiota intervention in heart failure (GutHeart trial).

Clinical and scientific focus 

More recently, the clinical and scientific focus has shifted to also include COVID-19, as part of the Nordic branch of the WHO solidarity trial, as coordinator of the national reference group on COVID-19 treatment in Norway and as co-applicant for the Horizon 2020 consortium EU-RESPONSE (European Research and Preparedness Network for Pandemics and Emerging Infectious Diseases). Trøseid is now chief investigator of the novel pan-European adaptive platform trial for COVID and emerging pandemics, EU SolidAct, set up to run phase II and phase III trials in around 15 European countries.
 

Tags: gut microbiota, immunology, inflammation, HIV, Covid-19, RCT

Publications

  • Aune, Susanne Kristine; Bonnevie-Svendsen, Martin; Nyborg, Christoffer; Trøseid, Marius; Seljeflot, Ingebjørg & Hisdal, Jonny [Show all 7 contributors for this article] (2022). Gut Leakage and Cardiac Biomarkers after Prolonged Strenuous Exercise. Medicine & Science in Sports & Exercise. ISSN 0195-9131. 54(9), p. 1476–1482. doi: 10.1249/MSS.0000000000002948.
  • Hentzien, Maxime; Owen, Andrew; Strub-Wourgaft, Nathalie; Pérez-Casas, Carmen; Trøseid, Marius & Calmy, Alexandra (2022). Rethinking treatment paradigms for the deployment of SARS-CoV-2 antiviral drugs on the shifting landscape of new variants. Frontiers in Microbiology. ISSN 1664-302X. 13. doi: 10.3389/fmicb.2022.998287.
  • Suarez-Zdunek, Moises Alberto; Høgh, Julie; Kirkegaard-Klitbo, Ditte Marie; Jensen, Anne Marie R.; Rupert, Adam & Trøseid, Marius [Show all 9 contributors for this article] (2022). High incidence of subclinical peripheral artery disease in people with HIV. AIDS (London). ISSN 0269-9370. 36(10), p. 1355–1362. doi: 10.1097/QAD.0000000000003252.
  • Gelpi, M; Vestad, Beate; Raju, Sajan; Hansen, Simen Hyll; Høgh, J & Midttun, Øivind [Show all 13 contributors for this article] (2022). Association of the Kynurenine Pathway of Tryptophan Metabolism with Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation. Journal of Infectious Diseases. ISSN 0022-1899. 225(11), p. 1948–1954. doi: 10.1093/infdis/jiac018.
  • Larsen, Christopher Storm; Hande, Liv Nesse; Kummen, Martin; Thunhaug, Hilde; Vestad, Beate & Hansen, Simen Hyll [Show all 10 contributors for this article] (2022). Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention–a pilot trial. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 82(5), p. 363–370. doi: 10.1080/00365513.2022.2102540. Full text in Research Archive
  • Knudsen, Andreas D.; Bouazzi, Randa; Afzal, Shoaib; Gelpi, Marco; Benfield, Thomas & Høgh, Julie [Show all 10 contributors for this article] (2022). Monocyte count and soluble markers of monocyte activation in people living with HIV and uninfected controls. BMC Infectious Diseases. ISSN 1471-2334. 22(1). doi: 10.1186/s12879-022-07450-y.
  • Tveita, Anders Aune; Murphy, Sarah Louise Mikalsen; Holter, Jan Cato; Kildal, Anders Benjamin; Michelsen, Annika Elisabet & Lerum, Tøri Vigeland [Show all 28 contributors for this article] (2022). High circulating levels of the homeostatic chemokines CCL19 and CCL21 predict mortality and disease severity in Covid-19. Journal of Infectious Diseases. ISSN 0022-1899. doi: 10.1093/infdis/jiac313. Full text in Research Archive
  • Trøseid, Marius; Dahl, Tuva Børresdatter; Holter, Jan Cato; Kildal, Anders Benjamin; Murphy, Sarah Louise Mikalsen & Yang, Kuan [Show all 28 contributors for this article] (2022). Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies. Journal of Internal Medicine. ISSN 0954-6820. p. 1–13. doi: 10.1111/joim.13549. Full text in Research Archive
  • Meyer-Myklestad, Malin Holm; Medhus, Asle Wilhelm; Stiksrud, Birgitte; Lorvik, Kristina Berg; Seljeflot, Ingebjørg & Hansen, Simen Hyll [Show all 13 contributors for this article] (2022). Probiotics to HIV-infected immunological nonresponders: Altered mucosal immunity and microbial diversity restricted to ileum. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 89(1), p. 77–86. doi: 10.1097/QAI.0000000000002817.
  • Vestad, Beate; Ueland, Thor; Lerum, Tøri Vigeland; Dahl, Tuva Børresdatter; Holm, Kristian & Barratt-Due, Andreas [Show all 37 contributors for this article] (2022). Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations. Journal of Internal Medicine. ISSN 0954-6820. 291(6), p. 801–812. doi: 10.1111/joim.13458.
  • Thudium, Rebekka F.; Knudsen, Andreas; Von Stemann, Jakob Hjorth; Hove-Skovsgaard, Malene; Hoel, Hedda Benedicte & Mocroft, Amanda [Show all 14 contributors for this article] (2021). Independent Association of Interleukin 6 With Low Dynamic Lung Function and Airflow Limitation in Well-Treated People With Human Immunodeficiency Virus. Journal of Infectious Diseases. ISSN 0022-1899. 223(10), p. 1690–1698. doi: 10.1093/infdis/jiaa600.
  • Thudium, Rebekka F.; Ringheim, Hedda; Ronit, Andreas; Hoel, Hedda; Benfield, Thomas & Mocroft, Amanda [Show all 12 contributors for this article] (2021). Independent Associations of Tumor Necrosis Factor-Alpha and Interleukin-1 Beta With Radiographic Emphysema in People Living With HIV. Frontiers in Immunology. ISSN 1664-3224. 12. doi: 10.3389/fimmu.2021.668113.
  • Kåsine, Trine; Riise, Anne Margarita Dyrhol; Barratt-Due, Andreas; Kildal, Anders Benjamin; Olsen, Inge Christoffer & Nezvalova-Henriksen, Katerina [Show all 39 contributors for this article] (2021). Neutrophil count predicts outcome in hospitalized COVID-19 patients. Results from the NOR-Solidarity trial. Journal of Internal Medicine. ISSN 0954-6820. 291(2), p. 241–243. doi: 10.1111/joim.13377.
  • Diallo, Alpha; Trøseid, Marius; Simensen, Victoria C; Boston, Anaïs; Demotes, Jacques & Olsen, Inge Christoffer [Show all 28 contributors for this article] (2021). Accelerating clinical trial implementation in the context of the COVID-19 pandemic: challenges, lessons learned and recommendations from DisCoVeRy and the EU-SolidAct EU response group. Clinical Microbiology and Infection (CMI). ISSN 1198-743X. 28(1), p. 1–6. doi: 10.1016/j.cmi.2021.10.011.
  • Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lello, Laura Sandra; Wang, Sainan & Jo, Eunji [Show all 28 contributors for this article] (2021). Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections. Viruses. ISSN 1999-4915. 13:2489(12), p. 1–18. doi: 10.3390/v13122489. Full text in Research Archive
  • Lerum, Tøri Vigeland; Maltzahn, Niklas; Aukrust, Pål; Trøseid, Marius; Nezvalova-Henriksen, Katerina & Kåsine, Trine [Show all 27 contributors for this article] (2021). Persistent pulmonary pathology after COVID-19 is associated with high viral load, weak antibody response, and high levels of matrix metalloproteinase-9. Scientific Reports. ISSN 2045-2322. 11, p. 1–12. doi: 10.1038/s41598-021-02547-x. Full text in Research Archive
  • Vestad, Beate; Nyman, Tuula A.; Hove-Skovsgaard, Malene; Stensland, Maria; Hoel, Hedda Benedicte & Siebke, Anne-Marie [Show all 13 contributors for this article] (2021). Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk. Scientific Reports. ISSN 2045-2322. 11(1). doi: 10.1038/s41598-021-01334-y. Full text in Research Archive
  • Drivsholm, Ninna; Knudsen, Andreas; Faurholt-Jepsen, Maria; Midttun, Øivind; Trøseid, Marius & Kirkegaard-Klitbo, Ditte M. [Show all 9 contributors for this article] (2021). Alterations in the Kynurenine Pathway of Tryptophan Metabolism Are Associated With Depression in People Living With HIV. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 87(2), p. e177–e181. doi: 10.1097/QAI.0000000000002664.
  • Aune, Susanne Kristine; Cwikiel, Joanna; Flaa, Arnljot; Arnesen, Harald; Solheim, Svein & Awoyemi, Ayodeji Olawale [Show all 9 contributors for this article] (2021). Gut leakage markers in response to strenuous exercise in patients with suspected coronary artery disease. Cells. ISSN 2073-4409. 10(9). doi: 10.3390/cells10092193. Full text in Research Archive
  • Hustad, Nina Berger; Degerud, Hanna M; Hjelmerud, Ingrid; Fraz, Mai Sasaki Aanensen; Nordøy, Ingvild & Trøseid, Marius [Show all 9 contributors for this article] (2021). Real-World Experiences With Facilitated Subcutaneous Immunoglobulin Substitution in Patients With Hypogammaglobulinemia, Using a Three-Step Ramp-Up Schedule. Frontiers in Immunology. ISSN 1664-3224. 12, p. 1–7. doi: 10.3389/fimmu.2021.670547. Full text in Research Archive
  • Awoyemi, Ayodeji Olawale; Mayerhofer, Christiane Caroline; Felix, Alex S.; Hov, Johannes Espolin Roksund; Moscavitch, Samuel D. & Lappegård, Knut Tore [Show all 23 contributors for this article] (2021). Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial. EBioMedicine. ISSN 2352-3964. 70. doi: 10.1016/j.ebiom.2021.103511. Full text in Research Archive
  • Barratt-Due, Andreas; Olsen, Inge Christoffer; Nezvalova-Henriksen, Katerina; Kåsine, Trine; Lund-Johansen, Fridtjof & Hoel, Hedda Benedicte [Show all 43 contributors for this article] (2021). Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial. Annals of Internal Medicine. ISSN 0003-4819. 174(9), p. 1261–1269. doi: 10.7326/M21-0653.
  • Aune, Susanne Kristine; Byrkjeland, Rune; Solheim, Svein; Arnesen, Harald; Trøseid, Marius & Awoyemi, Ayodeji Olawale [Show all 8 contributors for this article] (2021). Gut related inflammation and cardiorespiratory fitness in patients with CAD and type 2 diabetes: a sub-study of a randomized controlled trial on exercise training. Diabetology and Metabolic Syndrome. ISSN 1758-5996. 13(1), p. 1–9. doi: 10.1186/s13098-021-00655-2. Full text in Research Archive
  • Skaarud, Kristin Aneta Joan; Hov, Johannes Espolin Roksund; Hansen, Simen Hyll; Kummen, Martin; Valeur, Jørgen & Seljeflot, Ingebjørg [Show all 12 contributors for this article] (2021). Mortality and microbial diversity after allogenic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial. Scientific Reports. ISSN 2045-2322. doi: 10.1038/s41598-021-90976-z. Full text in Research Archive
  • Dhillon, Amandeep Kaur; Rupp, Christian; Bergquist, Annika; Voitl, Robert; Folseraas, Trine & Trøseid, Marius [Show all 12 contributors for this article] (2021). Associations of neopterin and kynurenine–tryptophan ratio with survival in primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 56(4), p. 443–452. doi: 10.1080/00365521.2021.1880627. Full text in Research Archive
  • Meyer-Myklestad, Malin Holm; Medhus, Asle Wilhelm; Lorvik, Kristina Berg; Seljeflot, Ingebjørg; Hansen, Simen Hyll & Holm, Kristian [Show all 13 contributors for this article] (2020). HIV-infected immunological non-responders have colon-restricted gut mucosal immune dysfunction. Journal of Infectious Diseases. ISSN 0022-1899. doi: 10.1093/infdis/jiaa714. Full text in Research Archive
  • Kummen, Martin; Thingholm, Louise B.; Rühlemann, Malte C.; Holm, Kristian; Hansen, Simen Hyll & Moitinho-Silva, Lucas [Show all 22 contributors for this article] (2020). Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis. Gastroenterology. ISSN 0016-5085. doi: 10.1053/j.gastro.2020.12.058. Full text in Research Archive
  • Mayerhofer, Christiane Caroline; Kummen, Martin; Holm, Kristian; Broch, Kaspar; Awoyemi, Ayodeji Olawale & Vestad, Beate [Show all 17 contributors for this article] (2020). Low fibre intake is associated with gut microbiota alterations in chronic heart failure. ESC Heart Failure. ISSN 2055-5822. 7(2), p. 456–466. doi: 10.1002/ehf2.12596. Full text in Research Archive
  • Nordøy, Ingvild; Fraz, Mai Sasaki Aanensen; Trøseid, Marius; Fevang, Børre & Aukrust, Pål (2020). Høyt serum-ferritin ikke kun uttrykk for leversvikt. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 140(8). doi: 10.4045/tidsskr.20.0376.
  • Hove-Skovsgaard, Malene; Abildgaard, Julie; Gelpi, Marco; Gaardbo, Julie C.; Kolte, Lilian & Ullum, Henrik [Show all 9 contributors for this article] (2020). No evidence of a synergistic effect of HIV infection and diabetes mellitus type 2 on fat distribution, plasma adiponectin or inflammatory markers. BMC Infectious Diseases. ISSN 1471-2334. 20(1). doi: 10.1186/s12879-020-05594-3. Full text in Research Archive
  • Gelpi, Marco; Vestad, Beate; Hansen, Simen Hyll; Holm, Kristian; Drivsholm, Ninna & Götz, Alexandra [Show all 17 contributors for this article] (2020). Impact of human immunodeficiency virus-related gut microbiota alterations on metabolic comorbid conditions. Clinical Infectious Diseases. ISSN 1058-4838. 71(8), p. e359–e367. doi: 10.1093/cid/ciz1235. Full text in Research Archive
  • Macpherson, Magnhild Eide; Hov, Johannes Espolin Roksund; Ueland, Thor; Dahl, Tuva Børresdatter; Kummen, Martin & Otterdal, Kari [Show all 14 contributors for this article] (2020). Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency. Frontiers in Immunology. ISSN 1664-3224. 11. doi: 10.3389/fimmu.2020.574500. Full text in Research Archive
  • Hoel, Hedda Benedicte; Heggelund, Lars; Reikvam, Dag Henrik; Stiksrud, Birgitte; Ueland, Thor & Michelsen, Annika [Show all 15 contributors for this article] (2020). Elevated markers of gut leakage and inflammasome activation in COVID-19 patients with cardiac involvement. Journal of Internal Medicine. ISSN 0954-6820. doi: 10.1111/joim.13178. Full text in Research Archive
  • Gelpi, Marco; Ueland, Per Magne; Trøseid, Marius; Mocroft, Amanda; Lebech, Anne-Mette & Ullum, Henrik [Show all 9 contributors for this article] (2020). Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus. Journal of Infectious Diseases. ISSN 0022-1899. 221(3), p. 419–427. doi: 10.1093/infdis/jiz465.
  • Hoel, Hedda Benedicte; Ueland, Thor; Knudsen, Andreas; Kjær, Andreas; Michelsen, Annika & Sagen, Ellen Lund [Show all 12 contributors for this article] (2020). Soluble Markers of Interleukin 1 Activation as Predictors of First-Time Myocardial Infarction in HIV-Infected Individuals. Journal of Infectious Diseases. ISSN 0022-1899. 221(4), p. 506–509. doi: 10.1093/infdis/jiz253.
  • Hoel, Hedda Benedicte; Ueland, Thor; Hove-Skovsgaard, Malene; Hartling, Hans Jakob; Gelpi, Marco & Benfield, Thomas [Show all 11 contributors for this article] (2020). Soluble T-Cell Immunoglobulin Mucin Domain-3 Is Associated With Hepatitis C Virus Coinfection and Low-Grade Inflammation During Chronic Human Immunodeficiency Virus Infection. Open Forum Infectious Diseases. ISSN 2328-8957. 29(7). doi: 10.1093/ofid/ofaa033. Full text in Research Archive
  • Kummen, Martin; Solberg, Ole Geir; Larsen, Christopher Storm; Holm, Kristian; Ragnarsson, Asgrimur & Trøseid, Marius [Show all 18 contributors for this article] (2020). Rosuvastatin alters the genetic composition of the human gut microbiome. Scientific Reports. ISSN 2045-2322. 10:5397, p. 1–9. doi: 10.1038/s41598-020-62261-y. Full text in Research Archive
  • Fretheim, Håvard Halland; Chung, Brian K.; Didriksen, Henriette; Bækkevold, Espen Sønderaal; Midtvedt, Øyvind & Brunborg, Cathrine [Show all 18 contributors for this article] (2020). Fecal Microbiota Transplantation in Systemic Sclerosis: A Double-Blind, Placebo-Controlled Randomized Pilot Trial. PLOS ONE. ISSN 1932-6203. 15:e0232739(5), p. 1–14. doi: 10.1371/journal.pone.0232739. Full text in Research Archive
  • Trøseid, Marius; Andersen, Geir Øystein; Broch, Kaspar & Hov, Johannes Espolin Roksund (2020). The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions. EBioMedicine. ISSN 2352-3964. 52:102649, p. 1–10. doi: 10.1016/j.ebiom.2020.102649. Full text in Research Archive
  • Reikvam, Dag Henrik; Meyer-Myklestad, Malin Holm; Trøseid, Marius & Stiksrud, Birgitte (2020). Probiotics to manage inflammation in HIV infection. Current Opinion in Infectious Diseases. ISSN 0951-7375. 33(1), p. 34–43. doi: 10.1097/QCO.0000000000000612.
  • Trøseid, Marius; Mayerhofer, Christiane Caroline; Broch, Kaspar; Arora, Satish; Svardal, Asbjørn M. & Hov, Johannes Espolin Roksund [Show all 14 contributors for this article] (2019). The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection. The Journal of Heart and Lung Transplantation. ISSN 1053-2498. 38(10), p. 1097–1103. doi: 10.1016/j.healun.2019.06.003. Full text in Research Archive
  • Stiksrud, Birgitte; Aass, Hans Christian Dalsbotten; Lorvik, Kristina Berg; Ueland, Thor; Trøseid, Marius & Dyrhol-Riise, Anne Ma (2019). Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery. AIDS (London). ISSN 0269-9370. 33(7), p. 1117–1129. doi: 10.1097/QAD.0000000000002173. Full text in Research Archive
  • Awoyemi, Ayodeji Olawale; Trøseid, Marius; Arnesen, Harald; Solheim, Svein & Seljeflot, Ingebjørg (2019). Effects of dietary intervention and n-3 PUFA supplementation on markers of gut-related inflammation and their association with cardiovascular events in a high-risk population. Atherosclerosis. ISSN 0021-9150. 286, p. 53–59. doi: 10.1016/j.atherosclerosis.2019.05.004.
  • Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin & Rashidi, Azita [Show all 18 contributors for this article] (2019). Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency. Scientific Reports. ISSN 2045-2322. 9:167, p. 1–10. doi: 10.1038/s41598-018-35367-7. Full text in Research Archive
  • Dhillon, Amandeep Kaur; Kummen, Martin; Trøseid, Marius; Åkra, Sissel; Liaskou, Evaggelia & Moum, Bjørn [Show all 10 contributors for this article] (2019). Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis. Liver international (Print). ISSN 1478-3223. 39(2), p. 371–381. doi: 10.1111/liv.13979. Full text in Research Archive
  • Trøseid, Marius; Nordøy, Ingvild; Fevang, Børre & Aukrust, Pål (2018). Anbud på hivlegemidler er ikke faglig begrunnet. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 138(20), p. 1–3. doi: 10.4045/tidsskr.18.0808.
  • Arnbjerg, Caroline J; Vestad, Beate; Hov, Johannes Espolin Roksund; Pedersen, Karin K; Jespersen, Sofie & Johannesen, Helle H [Show all 15 contributors for this article] (2018). Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 78(4), p. 450–457. doi: 10.1097/QAI.0000000000001693.
  • Larsen, Christopher Storm; Stiksrud, Birgitte; Eriksen, Carsten; Eriksen, C.; Nowak, Piotr & Nowak, P. [Show all 14 contributors for this article] (2018). Microbial translocation revisited: targeting the endotoxic potential of gut microbes in HIV-infected individuals. AIDS (London). ISSN 0269-9370. 33(4), p. 645–653. doi: 10.1097/QAD.0000000000002087. Full text in Research Archive
  • Missailidis, Catharina; Neogi, Ujjwal; Stenvinkel, Peter; Trøseid, Marius; Nowak, Piotr & Bergman, Peter (2018). The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages. AIDS (London). ISSN 0269-9370. 32(12), p. 1589–1598. doi: 10.1097/QAD.0000000000001813. Full text in Research Archive
  • Awoyemi, Ayodeji Olawale; Trøseid, Marius; Arnesen, Harald; Solheim, Svein & Seljeflot, Ingebjørg (2018). Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: A cross-sectional study. Diabetology and Metabolic Syndrome. ISSN 1758-5996. 10(1). doi: 10.1186/s13098-018-0360-3. Full text in Research Archive
  • Mayerhofer, Christiane Caroline; Awoyemi, Ayodeji Olawale; Moscavitch, Samuel D.; Lappegård, Knut Tore; Hov, Johannes Espolin Roksund & Aukrust, Pål [Show all 13 contributors for this article] (2018). Design of the GutHeart-targeting gut microbiota to treat heart failure-trial: a Phase II, randomized clinical trial. ESC Heart Failure. ISSN 2055-5822. 5, p. 978–985. doi: 10.1002/ehf2.12332. Full text in Research Archive
  • Hoel, Hedda Benedicte; Hove-Skovsgaard, Malene; Hov, Johannes Espolin Roksund; Gaardbo, Julie Christine; Holm, Kristian & Kummen, Martin [Show all 17 contributors for this article] (2018). Impact of HIV and type 2 diabetes on gut microbiota diversity, tryptophan catabolism and endothelial dysfunction. Scientific Reports. ISSN 2045-2322. 8. doi: 10.1038/s41598-018-25168-3. Full text in Research Archive
  • Hovland, Anders; Nestvold, Torunn Kristin; Bohov, Pavol; Trøseid, Marius; Aukrust, Pål & Berge, Rolf Kristian [Show all 9 contributors for this article] (2017). Bariatric surgery reduces fasting total fatty acids and increases n-3 polyunsaturated fatty acids in morbidly obese individuals. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 77(8), p. 628–633. doi: 10.1080/00365513.2017.1393691. Full text in Research Archive
  • Mayerhofer, Christiane Caroline; Ueland, Thor; Broch, Kaspar; Vincent, Royce P.; Cross, Gemma F. & Dahl, Christen Peder [Show all 10 contributors for this article] (2017). Increased secondary/primary bile acid ratio in chronic heart failure. Journal of Cardiac Failure. ISSN 1071-9164. 23(9), p. 666–671. doi: 10.1016/j.cardfail.2017.06.007. Full text in Research Archive
  • Haissman, Judith M.; Haugaard, Anna K.; Ostrowski, Sisse R.; Berge, Rolf Kristian; Hov, Johannes Espolin Roksund & Trøseid, Marius [Show all 7 contributors for this article] (2017). Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection. BMC Infectious Diseases. ISSN 1471-2334. 17:445, p. 1–8. doi: 10.1186/s12879-017-2547-x.
  • Hove-Skovsgaard, Malene; Gaardbo, Julie Christine; Kolte, Lilian; Winding, Kamilla; Seljeflot, Ingebjørg & Svardal, Asbjørn M. [Show all 11 contributors for this article] (2017). HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation. BMC Infectious Diseases. ISSN 1471-2334. 17:234, p. 1–8. doi: 10.1186/s12879-017-2334-8. Full text in Research Archive
  • Gelpi, Marco; Hartling, Hans Jakob; Ueland, Per Magne; Ullum, Henrik; Trøseid, Marius & Nielsen, Susanne D. (2017). Tryptophan catabolism and immune activation in primary and chronic HIV infection. BMC Infectious Diseases. ISSN 1471-2334. 17:349, p. 1–8. doi: 10.1186/s12879-017-2456-z.
  • Prebensen, Christian; Trøseid, Marius; Ueland, Thor; Dahm, Anders Erik A; Sandset, Per Morten & Aaberge, Ingeborg Sundsvalen [Show all 10 contributors for this article] (2017). Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial. PLOS ONE. ISSN 1932-6203. 12(5). doi: 10.1371/journal.pone.0176527. Full text in Research Archive
  • Kummen, Martin; Vesterhus, Mette; Trøseid, Marius; Moum, Bjørn; Svardal, Asbjørn M. & Boberg, Kirsten Muri [Show all 10 contributors for this article] (2016). Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function. United European Gastroenterology journal. ISSN 2050-6406. 5(4), p. 532–541. doi: 10.1177/2050640616663453.
  • Jespersen, Sofie; Pedersen, Karin Kæreby; Anesten, Birgitta; Zetterberg, Henrik; Fuchs, Dietmar & Gisslen, Magnus [Show all 9 contributors for this article] (2016). Soluble CD14 in cerebrospinal fluid is associated with markers of inflammation and axonal damage in untreated HIV-infected patients: A retrospective cross-sectional study. BMC Infectious Diseases. ISSN 1471-2334. 16(1). doi: 10.1186/s12879-016-1510-6.
  • Haissman, Judith M.; Haugaard, Anna K; Knudsen, Andreas; Kristoffersen, Ulrik S.; Seljeflot, Ingebjørg & Pedersen, Karin K. [Show all 13 contributors for this article] (2016). Marker of endothelial dysfunction asymmetric dimethylarginine is elevated in HIV infection but not associated with subclinical atherosclerosis. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 73(5), p. 507–513. doi: 10.1097/QAI.0000000000001148.
  • Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne & Trøseid, Marius [Show all 8 contributors for this article] (2016). Plasma IP-10 is increased in immunological nonresponders and associated with activated regulatory T cells and persisting low CD4 counts. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 73(2), p. 138–148. doi: 10.1097/QAI.0000000000001080.
  • Trøseid, Marius; Hov, Johannes Espolin Roksund; Nestvold, Torunn Kristin; Thoresen, Hanne; Berge, Rolf Kristian & Svardal, Asbjørn M. [Show all 7 contributors for this article] (2016). Major increase in microbiota-dependent proatherogenic metabolite TMAO one year after bariatric surgery. Metabolic Syndrome and Related Disorders. ISSN 1540-4196. 14(4), p. 197–201. doi: 10.1089/met.2015.0120. Full text in Research Archive
  • Jørgensen, Silje Fjellgård; Trøseid, Marius; Kummen, Martin; Anmarkrud, Jarl Andreas; Michelsen, Annika & Osnes, Liv T. N. [Show all 21 contributors for this article] (2016). Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation. Mucosal Immunology. ISSN 1933-0219. doi: 10.1038/mi.2016.18.
  • Kummen, Martin; Holm, Kristian; Anmarkrud, Jarl Andreas; Nygård, Ståle; Vesterhus, Mette & Høivik, Marte [Show all 14 contributors for this article] (2016). The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls. Gut. ISSN 0017-5749. 66(4), p. 611–619. doi: 10.1136/gutjnl-2015-310500.
  • Skagen, Karolina Ryeng; Trøseid, Marius; Ueland, Thor; Holm, Sverre; Abbas, Azhar & Gregersen, Ida [Show all 17 contributors for this article] (2016). The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis. Atherosclerosis. ISSN 0021-9150. 247, p. 64–69. doi: 10.1016/j.atherosclerosis.2016.01.033.
  • Haissman, Judith M.; Knudsen, Andreas; Hoel, Hedda B; Kjær, Andreas; Kristoffersen, Ulrik S. & Berge, Rolf Kristian [Show all 13 contributors for this article] (2016). Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated with First-Time Myocardial Infarction in HIV Infection. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 71(2), p. 130–136. doi: 10.1097/QAI.0000000000000843.
  • Nowak, Piotr; Trøseid, Marius; Avershina, Ekaterina; Barqasho, Babilonia; Neogi, Ujjwal & Holm, Kristian [Show all 12 contributors for this article] (2015). Gut microbiota diversity predicts immune status in HIV-1 infection. AIDS (London). ISSN 0269-9370. 29(18), p. 2409–2418. doi: 10.1097/QAD.0000000000000869.
  • Hartling, Hans Jakob; Birch, Carsten; Gaardbo, Julie C.; Hove, Malene; Trøseid, Marius & Clausen, Mette Rye [Show all 9 contributors for this article] (2015). T-cell homeostasis in chronic HCV-infected patients treated with interferon and ribavirin or an interferon-free regimen. APMIS - Journal of Pathologiy, Microbiology and Immunology. ISSN 0903-4641. 123(10), p. 903–911. doi: 10.1111/apm.12429.
  • Pedersen, Karin K.; Eiersted, Morten R.; Gaardbo, Julie C.; Pedersen, Maria; Gerstoft, Jan & Trøseid, Marius [Show all 7 contributors for this article] (2015). Lower self-reported quality of life in HIV-infected patients on cART and with low comorbidity compared with healthy controls. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 70(1), p. 16–22. doi: 10.1097/QAI.0000000000000697.
  • Gaardbo, Julie C.; Trøseid, Marius; Stiksrud, Birgitte; Midttun, Øivind; Ueland, Per Magne & Ullum, Henrik [Show all 7 contributors for this article] (2015). Increased tryptophan catabolism is associated with depletion of Tc17/MAIT cells, and lower CD4 cell count in HIV-1 infected patients on cART after two years of follow-up. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 70(3), p. 228–235. doi: 10.1097/QAI.0000000000000758.
  • Stiksrud, Birgitte; Nowak, Piotr; Nwosu, Felix Chinweije; Kvale, Dag; Thalme, Anders & Sönnerborg, Anders [Show all 15 contributors for this article] (2015). Reduced levels of D-dimer and changes in gut microbiota composition after probiotic intervention in HIV-infected individuals on stable ART. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 70(4), p. 329–337. doi: 10.1097/QAI.0000000000000784.

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  • Trøseid, Marius (2017). Book of Abstracts: 4rd National Microbiota Conference. Universitetet i Oslo. ISBN 000-00-000-0000-0. 200 p.

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  • Gregersen, Ida; Ueland, Thor; Holter, Jan Cato; Olsen, Maria Belland; Michelsen, Annika Elisabet & Murphy, Sarah L [Show all 22 contributors for this article] (2022). CXCL16 associates with adverse outcome and cardiac involvement in hospitalized patients with Covid-19. Journal of Infection. ISSN 0163-4453. doi: 10.1016/j.jinf.2022.09.029.
  • Murphy, Sarah Louise Mikalsen; Halvorsen, Bente; Barratt-Due, Andreas; Dyrhol-Riise, Anne Ma; Aukrust, Pål & Trøseid, Marius [Show all 7 contributors for this article] (2022). Remdesivir modifies interferon response in hospitalized COVID-19 patients. Journal of Infection. ISSN 0163-4453. 85(5), p. 573–607. doi: 10.1016/j.jinf.2022.07.021.
  • Trøseid, Marius; Diallo, Alpha; Hites, Maya; Røttingen, John-Arne & Yazdanpanah, Yazdan (2022). Accelerating clinical trial implementation in the context of the COVID-19 pandemic: author's response. Clinical Microbiology and Infection (CMI). ISSN 1198-743X. 28(5), p. 743–744. doi: 10.1016/j.cmi.2021.12.014.
  • Trøseid, Marius; Hites, Maya; Barratt-Due, Andreas; Ader, Florence & Yazdanpanah, Yazdan (2021). Assessing the evidence on remdesivir. The Lancet Infectious Diseases. ISSN 1473-3099. 21(12), p. 1630–1631. doi: 10.1016/S1473-3099%2821%2900695-2.
  • Tangen, Jorun; Aukrust, Pål; Barrat-Due, A; Trøseid, Marius; Olsen, Inge Christoffer & Nezvalova-Henriksen, Katerina [Show all 15 contributors for this article] (2021). Cardiac function is normal in most patients recovered from COVID-19 .
  • Stø, Kristine; Valeur, Jørgen; Ueland, Thor; Malmstrøm, Gunn Helen; Bjerkeli, Vigdis & Kazmi, Syed Sajid Hussain [Show all 10 contributors for this article] (2021). Increased fecal levels of the SCFA butyrate may indicate poor absorption due to disrupted gut barrier in patients with carotid stenosis.
  • Trøseid, Marius (2020). Når covid-19 møter afrikansk helsevesen. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 104(7), p. 1–2. doi: 10.4045/tidsskr.20.0283.
  • Trøseid, Marius; Lutro, Olav & Ormaasen, Vidar (2020). Utprovende behandling for covid-19 bor forega i randomiserte studier. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 140(7), p. 1–3. doi: 10.4045/TIDSSKR.20.0282.
  • Meyer-Myklestad, Malin Holm; Kummen, Martin; Stiksrud, Birgitte; Holm, Kristian; Dyrhol-Riise, Anne Ma & Kvale, Dag [Show all 11 contributors for this article] (2019). ALTERED GUT IMMUNITY IN IMMUNOLOGICAL NONRESPONDERS PARTLY RESTORED BY PROBIOTICS.
  • Trøseid, Marius (2019). Benmargstransplantasjon - en kur mot hiv? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 139(7). doi: 10.4045/tidsskr.19.0199.
  • Mayerhofer, Christiane Caroline; Awoyemi, Ayodeji Olawale; Hov, Johannes Espolin Roksund; Trøseid, Marius & Broch, Kaspar (2019). Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure. ESC Heart Failure. ISSN 2055-5822. 6(3), p. 557–558. doi: 10.1002/ehf2.12437.
  • Nilsen, Lisbeth; Hov, Johannes Espolin Roksund; Trøseid, Marius; Valeur, Jørgen & Midtvedt, Tore (2018). Forsker på om tarmbakteriene kan forutsi sykdom. [Newspaper]. Dagens Medisin.
  • Kummen, Martin; Mayerhofer, Christiane Caroline; Vestad, Beate; Broch, Kaspar; Awoyemi, Ayodeji Olawale & Storm-Larsen, Christopher [Show all 10 contributors for this article] (2018). Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts. Journal of the American College of Cardiology. ISSN 0735-1097. 71(10), p. 1184–1186. doi: 10.1016/j.jacc.2017.12.057.
  • Bernhoft, Aksel; Midtvedt, Tore; Eggesbø, Merete Åse; Aas, Anne-Marie; Berstad, Arnold & Harstad, Odd Magne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober - hvordan mater vi dem, og hva gjør de med oss? Årbok 2016 Det Norske Videnskaps-Akademi. Novus Forlag. ISSN 978-82-7099-888-3. p. 438–453.
  • Trøseid, Marius (2017). Gutmicrobiota and acute coronary syndromes: Ready for use in the emergency room? European Heart Journal. ISSN 0195-668X. 38(11), p. 825–827. doi: 10.1093/eurheartj/ehx005.
  • Kielland, Ingrid Røise; Stenvik, Bår; Øien, Torbjørn; Eggesbø, Merete Åse; Valeur, Jørgen & Birkeland, Stein-Erik [Show all 16 contributors for this article] (2017). Bakteriebomben. [Newspaper]. D2 - Dagens Næringsliv.
  • Bernhoft, Aksel; Berstad, Arnold; Eggesbø, Merete Åse; Garborg, Kjetil Kjeldstad; Harstad, Odd Magne & Holst-Jensen, Arne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober. Del III: Kan avføring brukes som behandling mot sykdommer? Forskning.no. ISSN 1891-635X.
  • Bernhoft, Aksel; Berstad, Arnold; Eggesbø, Merete Åse; Garborg, Kjetil Kjeldstad; Harstad, Odd Magne & Holst-Jensen, Arne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober. Del II: Disse sykdommene kan kobles til det som bor i tarmen. Forskning.no. ISSN 1891-635X.
  • Bernhoft, Aksel; Berstad, Arnold; Eggesbø, Merete Åse; Garborg, Kjetil Kjeldstad; Harstad, Odd Magne & Holst-Jensen, Arne [Show all 15 contributors for this article] (2017). Tarmens viktige mikrober. Del I: Tarmens viktige mikrober har stor betydning for helsen. Forskning.no. ISSN 1891-635X.
  • Jortveit, Jarle; Dahlslett, Thomas; Kvien, Elisabeth Hagelsten; Lundblad, Runar; Trøseid, Marius & Beitnes, Jan Otto (2016). En mann i 20-årene med magesmerter og bilyd over hjertet. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(3), p. 238–240. doi: 10.4045/tidsskr.15.0790.
  • Jortveit, Jarle; Dahlslett, Thomas; Kvien, Elisabeth Hagelsten; Lundblad, Runar; Trøseid, Marius & Beitnes, Jan Otto (2016). A man in his 20s with abdominal pain and heart murmurs. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(3), p. 238–240. doi: 10.4045/tidsskr.15.0790.
  • Knudsen, Andreas; Christensen, Thomas Emil; Thorsteinsson, Kristina; Ghotbi, Adam Ali; Hasbak, Philip & Lebech, Anne-Mette [Show all 12 contributors for this article] (2016). Microbiota-dependent marker TMAO is not associated with decreased myocardial perfusion in well-treated HIV-infected patients as assessed by 82 rubidium PET/CT. Journal of Acquired Immune Deficiency Syndromes. ISSN 1525-4135. 72(4), p. e83–85. doi: 10.1097/QAI.0000000000001044.
  • Kummen, Martin; Vesterhus, Mette; Trøseid, Marius; Moum, Bjørn; Svardal, Asbjørn M. & Boberg, Kirsten Muri [Show all 10 contributors for this article] (2015). P1174: Microbiota-dependent marker trimethylamine-N-oxide (TMAO) is associated with the severity of primary sclerosing cholangitis.
  • Kummen, Martin; Holm, Kristian; Anmarkrud, Jarl Andreas; Vesterhus, Mette; Høivik, Marte & Trøseid, Marius [Show all 12 contributors for this article] (2015). O082 : THE GUT MICROBIOTA IN PRIMARY SCLEROSING CHOLANGITIS DIFFERS FROM THAT OF HEALTHY CONTROLS AND ULCERATIVE COLITIS PATIENTS WITHOUT BILIARY DISEASE.
  • Kummen, Martin; Vesterhus, Mette; Trøseid, Marius; Moum, Bjørn; Svardal, Asbjørn M. & Boberg, Kirsten Muri [Show all 10 contributors for this article] (2015). MICROBIOTA-DEPENDENT MARKER TRIMETHYLAMINE-N-OXIDE (TMAO) IS ASSOCIATED WITH THE SEVERITY OF PRIMARY SCLEROSING CHOLANGITIS.
  • Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne & Berge, Rolf Kristian [Show all 9 contributors for this article] (2015). Plasma Interferon-inducible Protein 10 Levels, T-cell Activation and Regulation are Increased in HIV Immunological Non-Responders.
  • Hov, Johannes Espolin Roksund & Trøseid, Marius (2015). Persontilpasset tarmfloramedisin? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(7).

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Published Apr. 4, 2016 9:21 AM - Last modified Sep. 1, 2022 2:14 PM