Tuula Anneli Nyman

Image of Tuula Anneli Nyman
Norwegian version of this page
Phone +47 23073017
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Visiting address Sognsvannsveien 20 Rikshospitalet 0372 Oslo
Postal address OUS HF Rikshospitalet Postboks 4950 Nydalen 0424 Oslo

Head of Proteomics Core Facility since 1.5.2016 

Primary fields of research: proteomics, biological mass spectrometry, bioinformatics, innate immunity, cell signaling

 

Tags: innate immunity, mass spectrometry, proteomics, Cell Signaling

Publications

Selected recent publications

Lorey MB, Rossi K, Eklund KK, Nyman TA*, Matikainen S*. Global characterization of protein secretion from human macrophages following non-canonical caspase-4/5 inflammasome activation. Mol Cell Proteomics. 2017 Feb 14. [Epub ahead of print]

Cypryk W, Lorey M, Puustinen A, Nyman TA, Matikainen S. Proteomic and Bioinformatic Characterization of Extracellular Vesicles Released from Human Macrophages upon Influenza A Virus Infection. J Proteome Res. 2017;16:217-227

Söderholm S, Fu Y, Gaelings L, Belanov S, Yetukuri L, Berlinkov M, Cheltsov AV, Anders S, Aittokallio T, Nyman TA, Matikainen S, Kainov DE. Multi-Omics Studies towards Novel Modulators of Influenza A Virus-Host Interaction.Viruses. 2016 Sep 29;8(10). pii: E269. Review.

Välimäki E, Cypryk W, Virkanen J, Nurmi K, Turunen PM, Eklund KK, Åkerman KE, Nyman TA, Matikainen S. Calpain Activity Is Essential for ATP-Driven Unconventional Vesicle-Mediated Protein Secretion and Inflammasome Activation in Human Macrophages. J Immunol. 2016;197:3315-3325

Söderholm S, Kainov DE, Öhman T, Denisova OV, Schepens B, Kulesskiy E, Imanishi SY, Corthals G, Hintsanen P, Aittokallio T, Saelens X, Matikainen S*, Nyman TA*. Phosphoproteomics to characterize host response during influenza A virus infection of human macrophages. Mol Cell Proteomics. 2016;15:3203-3219

Christensen MH, Jensen SB, Miettinen JJ, Luecke S, Prabakaran T, Reinert LS, Mettenleiter T, Chen ZJ, Knipe DM, Sandri-Goldin RM, Enquist LW, Hartmann R, Mogensen TH, Rice SA, Nyman TA, Matikainen S, Paludan SR. HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression. EMBO J. 2016;35:1385-99.

Öhman T, Söderholm S, Paidikondala M, Lietzén N, Matikainen S, Nyman TA. Phosphoproteome characterization reveals that Sendai-virus infection activates mTOR signaling in human epithelial cells. Proteomics. 2015;15:2087-97.

Öhman T, Söderholm S, Hintsanen P, Välimäki E, Lietzén N, MacKintosh C, Aittokallio T, Matikainen S, Nyman TA. Phosphoproteomics Combined with Quantitative 14-3-3-affinity Capture Identifies SIRT1 and RAI as Novel Regulators of Cytosolic dsRNA Recognition Pathway. Mol Cell Proteomics. 2014;13,2604-17.

Cypryk W, Öhman T, Eskelinen E-L, Matikainen S, Nyman TA. Quantitative proteomics of extracellular vesicles released from human monocyte-derived macrophages upon β-glucan stimulation. J Proteome Res. 2014;13:2468-77.

Öhman T, Teirilä L, Lahesmaa AM, Kankkunen P, Veckman V, Saijo S, Wolff H, Hautaniemi S, Nyman TA*, Matikainen S*. Dectin-1 pathway activates robust autophagy-dependent unconventional protein secretion in human macrophages, J Immunol. 2014;192:5952-62.

Välimäki E, Miettinen J, Lietzén N, Matikainen S*, Nyman TA*. Monosodium urate activates Src/Pyk2/PI3 kinase and cathepsin dependent unconventional protein secretion from human primary macrophages. Mol Cell Proteomics. 2013;12:749-63.

Miettinen JJ, Matikainen S, Nyman TA. Global secretome characterisation of Herpes simplex virus 1 infected human primary macrophages, J Virol. 2012;86:12770-8.

Lietzén N, Öhman T*, Rintahaka J*, Julkunen I, Aittokallio T, Matikainen S*, Nyman TA*. Quantitative subcellular proteome and secretome profiling of Influenza A virus-infected human primary macrophages. PLoS Pathogens 2011 May;7(5):e1001340.

*equal contribution

  • Stamnæs, Jorunn; Stray, Daniel; Ekman, Maria; Sarna, Vikas Kumar; Nyman, Tuula Anneli; Lundin, Knut Erik Aslaksen & Sollid, Ludvig Magne (2021). In Well‐Treated Celiac Patients Low‐Level Mucosal Inflammation Predicts Response to 14‐day Gluten Challenge. Advanced Science.  ISSN 2198-3844. . doi: https://doi.org/10.1002/advs.202003526
  • Eieland, Alexander K.; Normann, Kjersti R.; Sundaram, Arvind Y. M.; Nyman, Tuula A.; Øystese, Kristin A. B.; Lekva, Tove; Berg, Jens P.; Bollerslev, Jens & Olarescu, Nicoleta C. (2020). Distinct pattern of endoplasmic reticulum protein processing and extracellular matrix proteins in functioning and silent corticotroph pituitary adenomas. Cancers.  ISSN 2072-6694.  12(10), s 1- 20 . doi: 10.3390/cancers12102980 Full text in Research Archive.
  • Gorski, Katarin; Spoljaric, Albert; Nyman, Tuula Anneli; Kaila, Kai; Battersby, Brendan J. & Lehesjoki, Anna-Elina (2020). Quantitative Changes in the Mitochondrial Proteome of Cerebellar Synaptosomes From Preclinical Cystatin B-Deficient Mice. Frontiers in Molecular Neuroscience.  ISSN 1662-5099.  13:570640, s 1- 13 . doi: 10.3389/fnmol.2020.570640
  • Harrison, Sean; Siller, Richard; Tanaka, Yoshiaki; Xiang, Yangfei; Patterson, Benjamin; Kempf, Henning; Melum, Espen; Åsrud, Kathrine Sivertsen; Dugarte, Maria Eugenia Chollet; Andersen, Elisabeth; Sandset, Per Morten; Baumgarten, Saphira Felicitas; Bonanini, Flavio; Kurek, Dorota; Mathapati, Santosh Sadashiv; Almaas, Runar; Sharma, Kulbhushan; Wilson, Steven Ray Haakon; Skottvoll, Frøydis Sved; Boger, Ida Caroline Sneis; Bogen, Inger Lise; Nyman, Tuula Anneli; Wu, Jun J.; Bezrouk, Ales; Cizkova, Dana; Mokrý, Jaroslav; Zweigerdt, Robert; Park, In-Hyun & Sullivan, Gareth (2020). Scalable production of tissue-like vascularised liver organoids from human PSCs.. BioRxiv.  ISSN 0362-4331. . doi: 10.1101/2020.12.02.406835
  • Krapf, Solveig Astrid; Lund, Jenny; Lundkvist, Malin; Grebstad Dale, Marianne; Nyman, Tuula Anneli; Thoresen, G. Hege & Kase, Eili Tranheim (2020). Pancreatic cancer cells show lower oleic acid oxidation and their conditioned medium inhibits oleic acid oxidation in human myotubes. Pancreatology (Print).  ISSN 1424-3903.  20(4), s 676- 682 . doi: 10.1016/j.pan.2020.04.014
  • Louwe, Maria Cornelia; Olsen, Maria Belland; Kaasbøll, Ole Jørgen; Yang, Kuan; Fosshaug, Linn Elisabeth Lillerud; Alfsnes, Katrine; Øgaard, Jonas; Rashidi, Azita; Skulberg, Vidar Magne; Yang, Mingyi; Fonseca, Davi de Miranda; Sharma, Animesh; Aronsen, Jan Magnus; Schrumpf, Elisabeth; Ahmed, Muhammad Shakil; Dahl, Christen Peder; Nyman, Tuula Anneli; Ueland, Thor; Melum, Espen; Halvorsen, Bente; Bjørås, Magnar; Attramadal, Håvard; Sjaastad, Ivar; Aukrust, Pål & Yndestad, Arne (2020). Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction. JACC: Basic to Translational Science.  ISSN 2452-302X.  5(12), s 1210- 1224 . doi: 10.1016/j.jacbts.2020.09.013 Full text in Research Archive.
  • Mathiesen, Sabrina Bech; Lunde, Marianne; Stensland, Maria; Martinsen, Marita; Nyman, Tuula Anneli; Christensen, Geir Arve & Carlson, Cathrine Rein (2020). The cardiac syndecan-2 interactome. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X.  8:792, s 1- 18 . doi: 10.3389/fcell.2020.00792 Full text in Research Archive.
  • Matikainen, Sampsa; Nyman, Tuula A. & Cypryk, Wojciech (2020). Inflammasomes: Exosomal miRNAs loaded for action. Journal of Cell Biology.  ISSN 0021-9525.  219:e202008130(10), s 1- 2 . doi: 10.1083/jcb.202008130
  • Matikainen, Sampsa; Nyman, Tuula Anneli & Cypryk, Wojciech (2020). Function and regulation of noncanonical caspase-4/5/11 inflammasome. Journal of Immunology.  ISSN 0022-1767.  204(12), s 3063- 3069 . doi: 10.4049/jimmunol.2000373
  • Savijoki, Kirsi; Miettinen, Ilkka; Nyman, Tuula Anneli; Kortesoja, Maarit; Hanski, Leena; Varmanen, Pekka & Fallarero, Adyary (2020). Growth Mode and Physiological State of Cells Prior to Biofilm Formation Affect Immune Evasion and Persistence of Staphylococcus aureus.. Microorganisms.  ISSN 2076-2607.  8:106(1), s 1- 24 . doi: 10.3390/microorganisms8010106 Full text in Research Archive. Show summary
  • Szibor, Marten; Schreckenberg, Rolf; Gizatullina, Zemfira; Dufour, Eric; Wiesnet, Marion; Dhandapani, Praveen K.; Debska-Vielhaber, Grazyna; Heidler, Juliana; Wittig, Ilka; Nyman, Tuula Anneli; Gärtner, Ulrich; Hall, Andrew R.; Pell, Victoria; Viscomi, Carlo; Krieg, Thomas; Murphy, Michael P.; Braun, Thomas; Gellerich, Frank; Schlüter, Klaus-Dieter & Jacobs, Howard T. (2020). Respiratory chain signalling is essential for adaptive remodelling following cardiac ischaemia. Journal of Cellular and Molecular Medicine.  ISSN 1582-1838.  24(6), s 3534- 3548 . doi: 10.1111/jcmm.15043 Full text in Research Archive.
  • Alexandrova, Elena; Giurato, Giorgio; Saggese, Pasquale; Pecoraro, Giovanni; Lamberti, Jessica; Ravo, Maria; Rizzo, Francesca; Rocco, Domenico; Tarallo, Roberta; Nyman, Tuula Anneli; Collina, Francesca; Cantile, Monica; Di Bonito, Maurizio; Botti, Gerardo; Nassa, Giovanni & Weisz, Alessandro (2019). Interaction proteomics identifies estrogen receptor beta association with multiple chromatin repressive complexes to inhibit cholesterol biosynthesis and exert an oncosuppressive role in triple-negative breast cancer.. Molecular & Cellular Proteomics.  ISSN 1535-9476. . doi: 10.1074/mcp.RA119.001817 Full text in Research Archive. Show summary
  • Hiltunen, Anna K.; Savijoki, Kirsi; Nyman, Tuula Anneli; Miettinen, Ilkka; Ihalainen, Petri; Peltonen, Jouko & Fallarero, Adyary (2019). Structural and functional dynamics of staphylococcus aureus biofilms and biofilm matrix proteins on different clinical materials. Microorganisms.  ISSN 2076-2607.  7(12) . doi: 10.3390/microorganisms7120584 Full text in Research Archive. Show summary
  • Lunde, Ngoc Dieu Nguyen; Gregersen, Ida; Ueland, Thor; Shetelig, Christian; Holm, Sverre; Kong, Xiang Yi; Michelsen, Annika; Otterdal, Kari; Yndestad, Arne; Broch, Kaspar; Gullestad, Lars; Nyman, Tuula Anneli; Bendz, Bjørn; Eritsland, Jan; Hoffmann, Pavel; Skagen, Karolina Ryeng; Gonçalves, Isabel; Nilsson, Jan; Grenegård, Magnus; Poreba, Marcin; Drag, Marcin; Seljeflot, Ingebjørg; Sporsheim, Bjørnar; Espevik, Terje; Skjelland, Mona; Johansen, Harald Thidemann; Solberg, Rigmor; Aukrust, Pål; Björbacka, Harry; Andersen, Geir Øystein & Halvorsen, Bente (2019). Legumain is upregulated in acute cardiovascular events and associated with improved outcome – potentially related to anti-inflammatory effects on macrophages. Atherosclerosis.  ISSN 0021-9150.  s 1- 9 . doi: 10.1016/j.atherosclerosis.2019.12.008 Full text in Research Archive.
  • Mathiesen, Sabrina Bech; Lunde, Marianne; Aronsen, Jan Magnus; Romaine, Andreas; Kaupang, Anita; Martinsen, Marita; De Souza, Gustavo Antonio; Nyman, Tuula Anneli; Sjaastad, Ivar; Christensen, Geir Arve & Carlson, Cathrine Rein (2019). The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP). Journal of Biological Chemistry.  ISSN 0021-9258.  294(22), s 8717- 8731 . doi: 10.1074/jbc.RA118.006423 Full text in Research Archive. Show summary
  • Nassa, Giovanni; Giurato, Giorgio; Salvati, Annamaria; Gigantino, Valerio; Pecoraro, Giovanni; Lamberti, Jessica; Rizzo, Francesca; Nyman, Tuula Anneli; Tarallo, Roberta & Weisz, Alessandro (2019). The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei. Scientific Data.  ISSN 2052-4463.  6(1), s 173 . doi: 10.1038/s41597-019-0179-2 Full text in Research Archive.
  • Nassa, Giovanni; Salvati, Annamaria; Tarallo, Roberta; Gigantino, Valerio; Alexandrova, Elena; Memoli, Domenico; Sellitto, Assunta; Rizzo, Francesca; Malanga, Donatella; Mirante, Teresa; Morelli, Eugenio; Nees, Matthias; Åkerfelt, Malin; Kangaspeska, Sara; Nyman, Tuula Anneli; Milanesi, Luciano; Giurato, Giorgio & Weisz, Alessandro (2019). Inhibition of histone methyltransferase DOT1L silences ER gene and blocks proliferation of antiestrogen-resistant breast cancer cells. Indian Journal of Pure & Applied Physics.  ISSN 0019-5596.  5(2), s 1- 14 . doi: 10.1126/sciadv.aav5590 Full text in Research Archive. Show summary
  • Richter, Uwe; Ng, Kah Ying; Suomi, Fumi; Marttinen, Paula; Turunen, Taina; Jackson, Christopher; Suomalainen, Anu; Vihinen, Helena; Jokitalo, Eija; Nyman, Tuula Anneli; Isokallio, Marita A.; Stewart, James B.; Mancini, Cecilia; Brusco, Alfredo; Seneca, Sara; Lombès, Anne; Taylor, Robert W. & Battersby, Brendan J. (2019). Mitochondrial stress response triggered by defects in protein synthesis quality control. Life Science Alliance (LSA).  ISSN 2575-1077.  2:e201800219(1), s 1- 17 . doi: 10.26508/lsa.201800219 Full text in Research Archive.
  • Savijoki, Kirsi; Nyman, Tuula Anneli; Kainulainen, Veera; Miettinen, Ilkka; Siljamaki, Pia; Fallarero, Adyary; Sandholm, Jouko; Satokari, Reetta & Varmanen, Pekka (2019). Growth mode and carbon source impact the surfaceome dynamics of lactobacillus rhamnosus GG. Frontiers in Microbiology.  ISSN 1664-302X.  10 . doi: 10.3389/fmicb.2019.01272 Full text in Research Archive.
  • Yang, Kuan; Lauritzen, Knut Husø; Olsen, Maria Belland; Dahl, Tuva Børresdatter; Ranheim, Trine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Aukrust, Pål; Halvorsen, Bente; Nyman, Tuula Anneli; Sandanger, Øystein & Yndestad, Arne (2019). Low cellular NAD+ compromises lipopolysaccharide-induced inflammatory responses via inhibiting TLR4 signal transduction in human monocytes. Journal of Immunology.  ISSN 0022-1767.  203(6), s 1598- 1608 . doi: 10.4049/jimmunol.1801382
  • Cypryk, Wojciech; Nyman, Tuula Anneli & Matikainen, Sampsa (2018). From inflammasome to exosome-does extracellular vesicle secretion constitute an inflammasome-dependent immune response?. Frontiers in Immunology.  ISSN 1664-3224.  9:2188, s 1- 8 . doi: 10.3389/fimmu.2018.02188 Show summary
  • Frohnmeyer, Esther; Deptula, Paulina; Nyman, Tuula Anneli; Laine, Pia K.S.; Vihinen, Helena; Paulin, Lars; Auvinen, Petri; Jokitalo, Eija; Piironen, Vieno; Varmanen, Pekka & Savijoki, Kirsi (2018). Secretome profiling of Propionibacterium freudenreichii reveals highly variable responses even among the closely related strains. Microbial Biotechnology.  ISSN 1751-7907.  11(3), s 510- 526 . doi: 10.1111/1751-7915.13254 Full text in Research Archive. Show summary
  • Giurato, Giorgio; Nassa, Giovanni; Salvati, Annamaria; Alexandrova, Elena; Rizzo, Francesca; Nyman, Tuula Anneli; Weisz, Alessandro & Tarallo, Roberta (2018). Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells. Scientific Data.  ISSN 2052-4463.  5:180031, s 1- 9 . doi: 10.1038/sdata.2018.31 Show summary
  • Nassa, Giovanni; Giurato, Giorgio; Cimmino, Giovanni; Rizzo, Francesca; Ravo, Maria; Salvati, Annamaria; Nyman, Tuula Anneli; Zhu, Yafeng; Vesterlund, Mattias; Lehtiö, Janne; Golino, Paolo; Weisz, Alessandro & Tarallo, Roberta (2018). Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications. Scientific Reports.  ISSN 2045-2322.  8:498, s 1- 12 . doi: 10.1038/s41598-017-18985-5 Show summary
  • Sikorski, Krzysztof; Mehta, Adi; Inngjerdingen, Marit; Thakor, Flourina Kumar; Kling, Simon; Kalina, Tomas; Nyman, Tuula Anneli; Stensland, Maria; Zhou, Wei; De Souza, Gustavo Antonio; Holden, Lars; Stuchly, Jan; Templin, Markus & Lund-Johansen, Fridtjof (2018). A high-throughput pipeline for validation of antibodies. Nature Methods.  ISSN 1548-7091.  15(11), s 909- 912 . doi: 10.1038/s41592-018-0179-8 Full text in Research Archive. Show summary
  • Bulanova, Daria; Ianevski, Aleksandr; Bugai, Andrii; Akimov, Yevhen; Kuivanen, Suvi; Paavilainen, Henrik; Kakkola, Laura; Nandania, Jatin; Turunen, Laura; Ohman, Tiina; Ala-Hongisto, Hanna; Pesonen, Hanna M; Kuisma, Marika S; Honkimaa, Anni; Walton, Emma Louise; Oksenych, Valentyn; Lorey, Martina B.; Guschin, Dmitry; Shim, Jungmin; Kim, Jinhee; Than, Thoa T; Chang, So Young; Hukkanen, Veijo; Kulesskiy, Evgeny; Marjomaki, Varpu S; Julkunen, Ilkka; Nyman, Tuula Anneli; Matikainen, Sampsa; Saarela, Jani S; Sane, Famara; Hober, Didier; Gabriel, Gulsah; De Brabander, Jef K; Martikainen, Miika; Windisch, Marc P; Min, Ji-Young; Bruzzone, Roberto; Aittokallio, Tero; Vaha-Koskela, Markus; Vapalahti, Olli; Pulk, Arto; Velagapudi, Vidya & Kainov, Denis (2017). Antiviral properties of chemical inhibitors of cellular anti-apoptotic Bcl-2 proteins. Viruses.  ISSN 1999-4915.  9(10) . doi: 10.3390/v9100271 Full text in Research Archive.
  • Deptula, Paulina; Chamlagain, Bhawani; Edelmann, Minnamari; Sangsuwan, Panchanit; Nyman, Tuula Anneli; Savijoki, Kirsi; Piironen, Vieno & Varmanen, Pekka (2017). Food-like growth conditions support production of active vitamin B12 by Propionibacterium freudenreichii 2067 without DMBI, the lower ligand base, or cobalt supplementation. Frontiers in Microbiology.  ISSN 1664-302X.  8 . doi: 10.3389/fmicb.2017.00368
  • Dumont, Vincent; Tolvanen, Tuomas A.; Kuusela, Sara; Wang, Hong; Nyman, Tuula Anneli; Lindfors, Sonja; Tienari, Jukka; Nisen, Harry; Suetsugu, Shiro; Plomann, Markus; Kawachi, Hiroshi & Lehtonen, Sanna (2017). PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease. The FASEB Journal.  ISSN 0892-6638.  31(9), s 3978- 3990 . doi: 10.1096/fj.201601265R
  • Gaelings, Lana; Söderholm, Sandra; Bugai, Andrii; Fu, Yu; Nandania, Jatin; Schepens, Bert; Lorey, Martina B.; Tynell, Janne; Vande Ginste, Liesbeth; Le Goffic, Ronan; Miller, Matthew S.; Kuisma, Marika; Marjomäki, Varpu; De Brabander, Jef; Matikainen, Sampsa; Nyman, Tuula Anneli; Bamford, Dennis H.; Saelens, Xavier; Julkunen, Ilkka; Paavilainen, Henrik; Hukkanen, Veijo; Velagapudi, Vidya & Kainov, Denis (2017). Regulation of kynurenine biosynthesis during influenza virus infection. The FEBS Journal.  ISSN 1742-464X.  284(2), s 222- 236 . doi: 10.1111/febs.13966
  • Lorey, Martina B.; Rossi, Katriina; Eklund, Kari K.; Nyman, Tuula Anneli & Matikainen, Sampsa (2017). Global characterization of protein secretion from human macrophages following non-canonical caspase-4/5 inflammasome activation. Molecular & Cellular Proteomics.  ISSN 1535-9476.  16(4), s S187- S199 . doi: 10.1074/mcp.M116.064840
  • Tarallo, Roberta; Giurato, Giorgio; Bruno, Giuseppina; Ravo, Maria; Rizzo, Francesca; Salvati, Annamaria; Ricciardi, Luca; Marchese, Giovanna; Cordella, Angela; Rocco, Teresa; Gigantino, Valerio; Pierri, Biancamaria; Cimmino, Giovanni; Milanesi, Luciano; Ambrosino, Concetta; Nyman, Tuula Anneli; Nassa, Giovanni & Weisz, Alessandro (2017). The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Genome Biology.  ISSN 1465-6906.  18:189, s 1- 27 . doi: 10.1186/s13059-017-1321-0
  • Nyman, Tuula Anneli; Cypryk, Wojciech; Lorey, Martina B.; Puustinen, Anne & Matikainen, Sampsa (2017). Proteomic and bioinformatic characterization of extracellular vesicles released from human macrophages upon influenza A virus infection. Journal of Proteome Research.  ISSN 1535-3893. . doi: https://doi.org/10.1021/acs.jproteome.6b00596 Show summary
  • Nyman, Tuula Anneli; Lorey, Martina B.; Cypryk, Wojciech & Matikainen, Sampsa (2017). Mass spectrometry-based proteomic exploration of the human immune system: focus on the inflammasome, global protein secretion, and T cells. Espert Review of Proteomics.  ISSN 1478-9450.  14(5), s 395- 407 . doi: 10.1080/14789450.2017.1319768
  • Nyman, Tuula Anneli & Matikainen, Sampsa (2017). Proteomics to study macrophage response to viral infection. Journal of Proteomics.  ISSN 1874-3919.  180, s 99- 107 . doi: 10.1016/j.jprot.2017.06.018 Full text in Research Archive. Show summary
  • Nyman, Tuula Anneli; Matikainen, Sampsa; Cypryk, Wojciech & Lorey, Martina B. (2017). Mass spectrometry-based proteomic exploration of the human immune system -focus on the inflammasome, global protein secretion, and T cells.. Espert Review of Proteomics.  ISSN 1478-9450. . doi: https://doi.org/10.1080/14789450.2017.1319768 Show summary
  • Nyman, Tuula Anneli; Matikainen, Sampsa; Lorey, Martina B.; Rossi, M & Eklund, Kari K. (2017). Global characterization of protein secretion from human macrophages following non-canonical caspase-4/5 inflammasome activation. Molecular & Cellular Proteomics.  ISSN 1535-9476. . doi: https://doi.org/10.1074/mcp.M116.064840 Full text in Research Archive. Show summary
  • Nyman, Tuula Anneli; Nassa, Giovanni; Tarallo, Roberta; Giurato, Giorgio; Bruno, G; Ravo, Maria; Rizzo, Francesca; Salvati, Annamaria; Ricciardi, Luca; Marchese, Giovanna; Cordella, Angela; Rocco, Teresa; Gigantino, Valerio; Pierri, Biancamaria; Cimmino, Giovanni; Milanesi, Luciano; Ambrosino, Concetta & Weisz, Alessandro (2017). The nuclear receptor ERβ engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Genome Biology.  ISSN 1465-6906. . doi: https://doi.org/10.1186/s13059-017-1321-0 Full text in Research Archive. Show summary
  • Anastasina, Maria; Le May, Nicolas; Bugai, Andrii; Fu, Yu; Söderholm, Sandra; Gaelings, Lana; Ohman, Tiina; Tynell, Janne; Kyttänen, Suvi; Barboric, Matjaz; Nyman, Tuula Anneli; Matikainen, Sampsa; Julkunen, Ilkka; Butcher, Sarah J.; Egly, Jean-Marc & Kainov, Denis E. (2016). Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes. Biochimica et Biophysica Acta. Gene Regulatory Mechanisms.  ISSN 1874-9399.  1859(11), s 1440- 1448 . doi: 10.1016/j.bbagrm.2016.09.005
  • Cypryk, Wojciech; Lorey, Martina; Puustinen, Anne; Nyman, Tuula Anneli & Matkainen, Sampsa (2016). Proteomic and Bioinformatic Characterization of Extracellular Vesicles Released from Human Macrophages upon Influenza A Virus Infection. Journal of Proteome Research.  ISSN 1535-3893.  16(1), s 217- 227 . doi: 10.1021/acs.jproteome.6b00596
  • Söderholm, Sandra; Kainov, Denis E.; Öhman, Tiina; Denisova, Oxana V.; Schepens, Bert; Kulesskiy, Evgeny; Imanishi, Susumu Y.; Corthals, Garry; Hintsanen, Petteri; Aittokallio, Tero; Saelens, Xavier; Matikainen, Sampsa & Nyman, Tuula Anneli (2016). Phosphoproteomics to characterize host response during influenza a virus infection of human macrophages. Molecular & Cellular Proteomics.  ISSN 1535-9476.  15(10), s 3203- 3219 . doi: 10.1074/mcp.M116.057984
  • Nyman, Tuula Anneli; Söderholm, Sandra; Kainov, Denis; Ohman, Tiina; Denisova, Oxana V.; Schepens, Bert; Kulesskiy, Evgeny; Imanishi, Susumu Y.; Corthals, Garry; Hintsanen, Petteri; Aittokallio, Tero; Saelens, Xavier & Matikainen, Sampsa (2016). Phosphoproteomics to Characterize Host Response During Influenza A Virus Infection of Human Macrophages. Molecular & Cellular Proteomics.  ISSN 1535-9476. . doi: 10.1074/mcp.m116.057984 Full text in Research Archive. Show summary

View all works in Cristin

  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Chan, Hanna; Abrahamsen, Greger; Kjelstrup, Hanna; Medina, Daniel; Nyman, Tuula Anneli & Spurkland, Anne (2019). Tyr192 in the Lck SH2 domain affects the regulation of Lck activity.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna; Nyman, Tuula Anneli & Spurkland, Anne (2018). Lck’s interactome is influenced by phosphorylation of Tyr192 in the Lck SH2 domain.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna; Nyman, Tuula Anneli & Spurkland, Anne (2018). Lck’s interactome is influenced by phosphorylation of Tyr192 in the Lck SH2 domain.
  • Borowicz, Pawel; Sundvold-Gjerstad, Vibeke; Abrahamsen, Greger; Kjelstrup, Hanna; Nyman, Tuula Anneli & Spurkland, Anne (2018). Lck’s interactome is influenced by phosphorylation of Tyr192 in the Lck SH2 domain.

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Published May 13, 2016 10:39 AM - Last modified Feb. 27, 2017 2:20 PM