The research includes translational research, clinical observational studies, and interventional trials. The overall aim is to improve understanding of pathophysiology, risk factors, and treatment of cerebrovascular disorders. 

We have several active projects, both on primary and secondary prevention, as well as pre-hospital and in-hospital treatment of acute stroke.

Our research aims to reduce incidences of stroke (biomarkers), reduce stroke severity (neuroprotection) and improve patient outcome (cognition and vascular dementia), and includes both clinical and translational studies.

Some ongoing projects

  • Atherosclerosis and cerebral infarction. 

    The research group has a particular interest in the relationship between atherosclerosis and cerebral infarction and has in collaboration with the Research Institute of Internal Medicine (RIIM) at Rikshospitalet, several ongoing translational studies in this field. The aim is to gain deeper insight into the pathophysiology of atherosclerotic development in the carotid arteries and its link to the risk of cerebral infarction.

  • Microbiota and cerebral infarction 

    In ongoing studies, we investigate whether bacteria and their metabolites in the gut and oral cavity influence the development of atherosclerosis and the risk of cerebral infarction.

  • Preeclampsia during pregnancy and later cerebrovascular disease

    This project examines whether preeclampsia during pregnancy is associated with an increased risk of subsequent cardiovascular disease, with particular emphasis on cerebral infarction.

  • Cerebral hemodynamics in vasculopathy and acute cerebrovascular conditions. 

    This group aims to quantify and measure levels of cognitive impairment after stroke and to identify biological and clinical markers associated with prognosis for cognitive disorders following incident stroke. Subgroup leader is Hege Ihle-Hansen.

  • Anti-inflammatory treatment in acute cerebral infarction

    In a recently initiated international multicenter study, we investigate whether anti-inflammatory treatment in combination with thrombectomy in patients with acute cerebral infarction improves functional outcomes compared to thrombectomy alone.