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Cerebrovascular diseases

The group has broad interest in atherosclerosis, inflammation and acute stroke, including multi-modal imaging methods such as MRI, PET and ultrasound.

We have several active projects, both on primary and secondary prevention, as well as pre-hospital and in-hospital treatment of acute stroke.

Our research aims to reduce incidences of stroke (biomarkers), reduce stroke severity (neuroprotection) and improve patient outcome (cognition and vascular dementia), and includes both clinical and translational studies.

Main research areas

  • Acute stroke, inflammation and the gut-brain axis. The main aim of this group is to study the role of inflammation in acute stroke, and the impact of gut microbiota on cerebrovascular disease. Subgroup leader is Karolina Skagen.
  • Pre-hospital and acute stroke. The focus of this group is to improve and implement prehospital diagnostics and treatment of acute stroke patients. Subgroup leader is Else Charlotte Sandset.
  • Acute stroke treatment and atrial fibrillation. The scientific research interest is acute stroke treatment, diagnostic workup in acute ischemic stroke and the relation between stroke and atrial fibrillation. Subgroup leader is Anne-Hege Aamodt.
  • Stroke and cognition. This group aims to quantify and measure levels of cognitive impairment after stroke and to identify biological and clinical markers associated with prognosis for cognitive disorders following incident stroke. Subgroup leader is Hege Ihle-Hansen.

Projects

  • The Gut and Oral bacteria, Atherosclerosis and Ischemic Stroke Study
  • Atherosclerosis, Inflammation and Ischemic Stroke Study
  • Acute cerebral thrombi: mapping the immuno-thrombotic content -developing clinical tools for identifying the embolic source
  • Advanced ultrasound methods in the assessment of carotid plaque instability
  • Inflammation, atherosclerosis and ischemic stroke in chronic rhematological disease
  • FETCH: Fetal microchimerism (FMC) and future maternal cardiovascular health
  • Hidden impairment after stroke
  • OSCAR; The Oslo Acute Revascularization Stroke Study
  • NOR-FIB 1; A nordic multi-center prospective observational study of the occurrence of AF in patients with cryptogenic stroke / TIA
  • NOR-CRAOS; The Norwegian Central Retinal Artery Occlusion and Thrombolysis Study
  • TEN-CRAOS; A randomised controlled trial with tenecteplase in central retinal artery occlusion
  • Para-NASPP; Diagnostics and triage of acute stroke by the National Institute of Stroke Scale (NIHSS) by paramedics, the Para-NASPP (Paramedic – Norwegian Acute Stroke Prehospital Project)
  • Treat-NASPP; Prehospital advanced diagnostics and treatment of acute stroke
  • The rural CT-study. A case-control study with pre-hospital treatment with intravenous thrombolysis in acute stroke at “Sjukestugu Ål”
  • Sex-differences in stroke
  • NorCOAST; The Norwegian Cognitive impairment after Stroke study. A descriptive cohort study recruiting patients from five Norwegian hospitals 
  • ACE 1950; The ACE 1950 Study is a prospective, population-based, cohort study of the cardio- and cerebrovascular health of all men and women born in 1950 in Akershus County, Norway

Cooperation

National

  • Research Institute of Internal Medicine, RH, OUH, Professor Bente Halvorsen
  • Department of cardiology, OUH
  • Department of Ophthalmology, OUH
  • Interventional Centre, OUH, Rikshospitalet, Professor Per Kristian Hol
  • Akerhus University Hospital
  • Østfold Hospital, Kalnes
  • Vestre Viken Hospital Trust
  • National Hospital of Epilepsy (SSE)
  • Department of Clinical and Molecular Medicine, NTNU, Professor Terje Espevik
  • Institute of basic medical science, biostatistics, OUH, MSc Cathrine Brunborg

International

  • Professor Craig Smith, Greater Manchester Comprehensive Stroke Center, UK
  • Professor Erik Biessen, University of Maastricht, The Netherlands
  • Professor Mayank Goyal, Department of Radiology and Clinical Neurosciences, University of Calgary, Canada
  • Professor Craig S. Anderson, The George Insitute for Global Health, China and Australia
  • Professor Philip M. Bath, Nottingham University, UK
  • Professor Urs Fischer, University Hospital Bern, Switzerland

 

Published Jan. 24, 2019 11:53 AM - Last modified Feb. 4, 2019 8:02 AM

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Participants

Detailed list of participants