For this purpose, we have implemented different single-cell transcriptomics methods that either gives full-length transcript coverage of few hundred cells at time or high-throughput method that can sequence thousands of cells in one single experiment. In addition, we probe the immune receptor repertoire both in bulk and at single-cell level using versatile protocols.
My group work in close collaboration with the comparative immunology groups led by Prof. Finn-Eirik Johansen and group leader Julien Resseguier. We have both wet lab biologists and bioinformatician in our groups to generate and analysis the large amount of data.
Projects
- High throughput single-cell transcriptomics of cod fish immune cells to charter the unique immune system in the absence of MHC class II and CD4+ T cells.
- Immunisation and infection studies to investigate the immune response both on the molecular level and functionally.
- In-depth characterization of the immune receptor loci and immune receptor repertoire of the Atlantic cod.
