Mathias Toft

Professor II - Nevrologisk avdeling
Bilde av Mathias Toft
English version of this page
Brukernavn
Besøksadresse OUS Rikshospitalet Sognsvannsveien 20 0372 Oslo
Postadresse OUS, Rikshospitalet Postboks 4950 Nydalen 0424 Oslo

Publikasjoner

  • Blauwendraat, Cornelis; Reed, Xylena; Krohn, Lynne; Heilbron, Karl; Bandres-Ciga, Sara; Tan, Manuela; Gibbs, J. Raphael; Hernandez, Dena G.; Kumaran, Ravindran; Langston, Rebekah; Bonet-Ponce, Luis; Alcalay, Roy N.; Hassin-Baer, Sharon; Greenbaum, Lior; Iwaki, Hirotaka; Leonard, Hampton; Grenn, Francis P.; Ruskey, Jennifer A.; Sabir, Marya; Ahmed, Sarah; Makarious, Mary B.; Pihlstrøm, Lasse; Toft, Mathias; van Hilten, Jacobus J.; Marinus, Johan; Schulte, Claudia; Brockmann, Kathrin; Sharma, Manu; Siitonen, Ari; Majamaa, Kari; Eerola-Rautio, Johanna; Tienari, Pentti; Pantelyat, Alexander; Hillis, Argye E.; Dawson, Ted M.; Rosenthal, Liana S.; Albert, Marilyn; Resnick, Susan M.; Ferrucci, Luigi; Morris, Christopher M.; Pletnikova, Olga; Troncoso, Juan; Grosset, Donald; Lesage, Suzanne; Corvol, Jean-Christophe; Brice, Alexis; Noyce, Alastair J.; Masliah, Eliezer; Wood, Nick; Hardy, John; Shulman, Lisa M.; Jankovic, Joseph; Shulman, Joshua M.; Heutink, Peter; Gasser, Thomas; Cannon, Paul; Scholz, Sonja W.; Morris, Huw R.; Cookson, Mark R.; Nalls, Mike A.; Gan-Or, Ziv & Singleton, Andrew B. (2020). Genetic modifiers of risk and age at onset in GBA associated Parkinson's disease and Lewy body dementia. Brain.  ISSN 0006-8950.  143(1), s 234- 248 . doi: 10.1093/brain/awz350
  • Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton; Makarious, Mary B.; Kim, Jonggeol J.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Smolensky, Luba; Amondikar, Ninad; Hutten, Samantha J.; Frasier, Mark; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; Van Deerlin, Vivianna M.; Hernandez, Dena G.; Gibbs, Raphael; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Andreassen, Ole Andreas; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B. & Nalls, Mike A. (2020). Differences in the presentation and progression of Parkinson's disease by sex. Movement Disorders.  ISSN 0885-3185.  s 1- 14 . doi: 10.1002/mds.28312
  • Krohn, Lynne; Wu, Richard Y. J.; Heilbron, Karl; Ruskey, Jennifer A.; Laurent, Sandra B.; Blauwendraat, Cornelis; Alam, Armaghan; Arnulf, Isabelle; Hu, Michele; Dauvilliers, Yves; Högl, Birgit; Toft, Mathias; Bjørnaraa, Kari Anne; Stefani, Ambra; Holzknecht, Evi; Monaca, Christelle Charley; Abril, Beatriz; Plazzi, Giuseppe; Antelmi, Elena; Ferini-Strambi, Luigi; Young, Peter; Heidbreder, Anna; Cochen De Cock, Valérie; Mollenhauer, Brit; Sixel-Döring, Friederike; Trenkwalder, Claudia; Sonka, Karel; Kemlink, David; Figorilli, Michela; Puligheddu, Monica; Dijkstra, Femke; Viaene, Mineke; Oertel, Wolfgang; Toffoli, Marco; Gigli, Gian Luigi; Valente, Mariarosaria; Gagnon, Jean-François; Nalls, Mike A.; Singleton, Andrew B.; Desautels, Alex; Montplaisir, Jacques; Cannon, Paul; Ross, Owen A.; Boeve, Bradley F.; Dupré, Nicolas; Fon, Edward A.; Postuma, Ronald B.; Pihlstrøm, Lasse; Rouleau, Guy A. & Gan-Or, Ziv (2020). Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies. Annals of Neurology.  ISSN 0364-5134.  87(4), s 584- 598 . doi: 10.1002/ana.25687
  • Blauwendraat, Cornelis; Heilbron, Karl; Vallerga, Costanza L; Bandres-Ciga, Sara; von Coelln, Rainer; Pihlstrøm, Lasse; Simón-Sánchez, Javier; Schulte, Claudia; Sharma, Manu; Krohn, Lynne; Siitonen, Ari; Iwaki, Hirotaka; Leonard, Hampton; Noyce, Alastair J.; Tan, Manuela; Gibbs, J. Raphael; Hernandez, Dena G.; Scholz, Sonja W.; Jankovic, Joseph; Shulman, Lisa M.; Lesage, Suzanne; Corvol, Jean-Christophe; Brice, Alexis; van Hilten, Jacobus J.; Marinus, Johan; Eerola-Rautio, Johanna; Tienari, Pentti; Majamaa, Kari; Toft, Mathias; Grosset, Donald; Gasser, Thomas; Heutink, Peter; Shulman, Joshua M.; Wood, Nicolas; Hardy, John; Morris, Huw R.; Hinds, David A.; Gratten, Jacob; Visscher, Peter M.; Gan-Or, Ziv; Nalls, Mike A. & Singleton, Andrew B. (2019). Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α‐synuclein mechanisms. Movement Disorders.  ISSN 0885-3185.  34(6), s 866- 875 . doi: 10.1002/mds.27659
  • Fernandez-Santiago, Ruben; Martín-Flores, Núria; Antonelli, Francesca; Cerquera, Catalina; Moreno, Verónica; Bandres-Ciga, Sara; Manduchi, Elisabetta; Tolosa, Eduard; Singleton, Andrew B.; Moore, Jason H.; Pihlstrøm, Lasse; Toft, Mathias; Martí, María-Josep; Ezquerra, Mario & Malagelada, Cristina (2019). SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson’s Disease. Movement Disorders.  ISSN 0885-3185.  34(9), s 1333- 1344 . doi: 10.1002/mds.27770
  • Flengsrud, Karoline; Toft, Mathias & Dietrichs, Espen (2019). Essensiell tremor. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  139(8), s 1- 5 . doi: 10.4045/tidsskr.18.0904
  • Iqbal, Zafar; Koht, Jeanette; Pihlstrøm, Lasse; Henriksen, Sandra Pilar; Cappelletti, Chiara; Russell, Michael Bjørn; de Souza, Osmar Norberto; Skogseid, Inger Marie & Toft, Mathias (2019). Missense mutations in DYT-TOR1A dystonia. Neurology: Genetics.  ISSN 2376-7839.  5:e343(4), s 1- 6 . doi: 10.1212/NXG.0000000000000343 Fulltekst i vitenarkiv.
  • Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton L.; Kim, Jonggeol J.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Hutten, Samantha J.; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; Van Deerlin, Vivianna M.; Hernandez, Dena G.; Gibbs, J. Raphael; Chitrala, Kumaraswamy Naidu; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Andreassen, Ole Andreas; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B. & Nalls, Mike A. (2019). Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts. Movement Disorders.  ISSN 0885-3185.  34(12), s 1839- 1850 . doi: 10.1002/mds.27845
  • Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton L.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Hutten, Samantha J.; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; van Deerlin, Vivianna M.; Hernandez, Dena G.; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B. & Nalls, Mike A. (2019). Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts. Neurology: Genetics.  ISSN 2376-7839.  5(4), s 1- 14 . doi: 10.1212/NXG.0000000000000348 Fulltekst i vitenarkiv.
  • Nalls, Mike A.; Blauwendraat, Cornelis; Vallerga, Costanza L.; Heilbron, Karl; Bandres-Ciga, Sara; Chang, Diana; Tan, Manuela; Kia, Demis A.; Noyce, Alastair J.; Xue, Angli; Bras, Jose; Young, Emily; von Coelln, Rainer; Simón-Sánchez, Javier; Schulte, Claudia; Sharma, Manu; Krohn, Lynne; Philstrøm, Lasse; Siitonen, Ari; Iwaki, Hirotaka; Leonard, Hampton; Faghri, Faraz; Gibbs, J. Raphael; Hernandez, Dena G.; Scholz, Sonja W.; Botía, Juan A.; Martinez, Maria; Corvol, Jean-Christophe; Lesage, Suzanne; Jankovic, Joseph; Shulman, Lisa M.; Sutherland, Margaret; Tienari, Pentti; Majamaa, Kari; Toft, Mathias; Andreassen, Ole Andreas; Bangale, Tushar; Brice, Alexis; Yang, Jian; Gan-Or, Ziv; Gasser, Thomas; Heutink, Peter; Shulman, Joshua M.; Wood, Nicholas W.; Hinds, David A.; Hardy, John A.; Morris, Huw R.; Gratten, Jacob; Visscher, Peter M.; Graham, Robert R. & Singleton, Andrew B. (2019). Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet Neurology.  ISSN 1474-4422.  18(12), s 1091- 1102 . doi: 10.1016/S1474-4422(19)30320-5
  • Puschmann, Andreas; Jimenez-Ferrer, Itzia; Lundblad-Andersson, Elin; Mårtensson, Emma; Hansson, Oskar; Odin, Per; Widner, Håkan; Brolin, Kajsa; Mzezewa, Ropafadzo; Kristensen, Jonas; Soller, Maria; Rödstrom, Emil Ygland; Ross, Owen A.; Toft, Mathias; Breedveld, Guido J; Bonifati, Vincenzo; Brodin, Lovisa; Zettergren, Anna; Sydow, Olof; Linder, Jan; Wirdefeldt, Karin; Svenningsson, Per; Nissbrandt, Hans; Belin, Andrea Carmine; Forsgren, Lars & Swanberg, Maria (2019). Low prevalence of known pathogenic mutations in dominant PD genes: A Swedish multicenter study. Parkinsonism & Related Disorders.  ISSN 1353-8020.  66, s 158- 165 . doi: 10.1016/j.parkreldis.2019.07.032
  • Rongve, Arvid; Witoelar, Aree; Ruiz, Agustín; Athanasiu, Lavinia; Abdelnour, Carla; Clarimon, Jordi; Heilmann-Heimbach, Stefanie; Hernández, Isabel; Moreno-Grau, Sonia; de Rojas, Itziar; Morenas-Rodríguez, Estrella; Fladby, Tormod; Sando, Sigrid Botne; Bråthen, Geir; Blanc, Frédéric; Bousiges, Olivier; Lemstra, Afina W.; van Steenoven, Inger; Londos, Elisabet; Almdahl, Ina Selseth; Pålhaugen, Lene; Eriksen, Jon Alm; Djurovic, Srdjan; Stordal, Eystein; Saltvedt, Ingvild; Ulstein, Ingun; Bettella, Francesco; Desikan, Rahul S.; Idland, Ane-Victoria; Toft, Mathias; Pihlstrøm, Lasse; Snaedal, Jon; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Stefánsson, Hreinn; Stefánsson, Kári; Ramírez, Alfredo; Aarsland, Dag & Andreassen, Ole Andreas (2019). GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study. Scientific Reports.  ISSN 2045-2322.  9 . doi: 10.1038/s41598-019-43458-2 Fulltekst i vitenarkiv.
  • Berge-Seidl, Victoria; Pihlstrøm, Lasse; Wszolek, Zbigniew K.; Ross, Owen A. & Toft, Mathias (2018). No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease. Neurobiology of Aging.  ISSN 0197-4580.  74, s 1- 5 . doi: 10.1016/j.neurobiolaging.2018.09.022
  • Bjerknes, Silje Kristin; Toft, Mathias; Konglund, Ane; Pham, Uyen Ha Gia; Waage, Trine Rygvold; Pedersen, Lena; Skjelland, Mona; Haraldsen, Ira Hebold; Andersson, Stein; Dietrichs, Espen & Skogseid, Inger Marie (2018). Multiple microelectrode recordings in STN-DBS surgery for Parkinson's disease: a randomized study. Movement Disorders Clinical Practice.  ISSN 2330-1619.  5(3), s 296- 305 . doi: 10.1002/mdc3.12621 Fulltekst i vitenarkiv.
  • Bjørnaraa, Kari Anne; Pihlstrøm, Lasse; Dietrichs, Espen & Toft, Mathias (2018). Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson's disease: A genetic association study. BMC Neurology.  ISSN 1471-2377.  18(20), s 1- 5 . doi: 10.1186/s12883-018-1023-6 Fulltekst i vitenarkiv.
  • Blauwendraat, Cornelis; Kia, Demis A.; Pihlstrøm, Lasse; Gan-Or, Ziv; Lesage, Suzanne; Gibbs, J. Raphael; Ding, Jinhui; Alcalay, Roy N.; Hassin-Baer, Sharon; Pittman, Alan M.; Brooks, Janet; Edsall, Connor; Chung, Sun Ju; Goldwurm, Stefano; Toft, Mathias; Schulte, Claudia; Hernandez, Dena; Singleton, Andrew B.; Nalls, Mike A.; Brice, Alexis; Scholz, Sonja W. & Wood, Nicholas W. (2018). Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease. Neurobiology of Aging.  ISSN 0197-4580.  64, s 159.e5- 159.e8 . doi: 10.1016/j.neurobiolaging.2017.12.012
  • Blauwendraat, Cornelis; Reed, Xylena; Kia, Demis A.; Gan-Or, Ziv; Lesage, Suzanne; Pihlstrøm, Lasse; Guerreiro, Rita; Gibbs, J. Raphael; Sabir, Marya; Ahmed, Sarah; Ding, Jinhui; Alcalay, Roy N.; Hassin-Baer, Sharon; Pittman, Alan M.; Brooks, Janet; Edsall, Connor; Hernandez, Dena G.; Chung, Sun Ju; Goldwurm, Stefano; Toft, Mathias; Schulte, Claudia; Bras, Jose; Wood, Nicholas W.; Brice, Alexis; Morris, Huw R.; Scholz, Sonja W.; Nalls, Mike A.; Singleton, Andrew B. & Cookson, Mark R. (2018). Frequency of loss of function variants in LRRK2 in Parkinson disease. JAMA Neurology.  ISSN 2168-6149.  75(11), s 1416- 1422 . doi: 10.1001/jamaneurol.2018.1885
  • Kristiansen, Madeleine; Maple-Grødem, Jodi; Alves, Guido Werner; Arepalli, Sampath; Hernandez, Dena G; Iwaki, Hirotaka; Nalls, Mike A; Singleton, Andrew; Tysnes, Ole-Bjørn; Toft, Mathias & Pihlstrøm, Lasse (2018). A paradoxical relationship between family history, onset age, and genetic risk in Parkinson's disease. Movement Disorders.  ISSN 0885-3185.  34(2), s 298- 299 . doi: 10.1002/mds.27555
  • Pihlstrøm, Lasse; Blauwendraat, Cornelis; Cappelletti, Chiara; Berge-Seidl, Victoria; Langmyhr, Margrete; Henriksen, Sandra Pilar; van de Berg, Wilma; Gibbs, J. Raphael; Cookson, Mark R; Singleton, Andrew B.; Nalls, Mike A & Toft, Mathias (2018). A comprehensive analysis of SNCA-related genetic risk in sporadic parkinson disease. Annals of Neurology.  ISSN 0364-5134.  84(1), s 117- 129 . doi: 10.1002/ana.25274
  • Berge, Victoria; Pihlstrøm, Lasse; Maple-Grødem, Jodi; Forsgren, Lars; Linder, Jan; Larsen, Jan Petter; Tysnes, Ole-Bjørn & Toft, Harald Mathias Strøm (2017). The GBA variant E326K is associated with Parkinson's disease and explains a genome-wide association signal. Neuroscience Letters.  ISSN 0304-3940.  658, s 48- 52 . doi: 10.1016/j.neulet.2017.08.040 Fulltekst i vitenarkiv.
  • Iqbal, Zafar; Rydning, Siri Lynne; Wedding, Iselin Marie; Koht, Jeanette; Pihlstrøm, Lasse; Rengmark, Aina Sylvia Haugen; Henriksen, Sandra Pilar; Tallaksen, Chantal & Toft, Harald Mathias Strøm (2017). Targeted high throughput sequencing in hereditary ataxia and spastic paraplegia. PLOS ONE.  ISSN 1932-6203.  12:e0174667(3), s 1- 19 . doi: 10.1371/journal.pone.0174667 Fulltekst i vitenarkiv.
  • Pihlstrøm, Lasse; Morset, Kristina Rebekka; Grimstad, Espen; Vitelli, Valeria & Toft, Mathias (2016). A cumulative genetic risk score predicts progression in Parkinson's disease. Movement Disorders.  ISSN 0885-3185.  31(4), s 487- 490 . doi: 10.1002/mds.26505
  • Bjørnarå, Kari Anne; Dietrichs, Espen & Toft, Mathias (2015). Longitudinal assessment of probable rapid eye movement sleep behaviour disorder in Parkinson's disease. European Journal of Neurology.  ISSN 1351-5101.  22(8), s 1242- 1244 . doi: 10.1111/ene.12723
  • Lill, Christina M.; Rengmark, Aina Sylvia Haugen; Pihlstrøm, Lasse; Fogh, Isabella; Shatunov, Aleksey; Sleiman, Patrick M.; Wang, Li-San; Liu, Tian; Lassen, Christina F.; Meissner, Esther; Alexopoulos, Panos; Calvo, Andrea; Chio, Adriano; Dizdar, Nil; Faltraco, Frank; Forsgren, Lars; Kirchheiner, Julia; Kurz, Alexander; Larsen, Jan Petter; Liebsch, Maria; Linder, Jan; Morrison, Karen E; Nissbrandt, Hans; Otto, Markus; Pahnke, Jens; Partch, Amanda; Restagno, Gabriella; Rujescu, Dan; Schnack, Cathrin; Shaw, Christopher E.; Shaw, Pamela J.; Tumani, Hayrettin; Tysnes, Ole-Bjørn; Valladares, Otto; Silani, Vincenzo; van den Berg, Leonard H.; Van Rheenen, Wouter; Veldink, Jan H.; Lindenberger, Ulman; Steinhagen-Thiessen, Elisabeth; Teipel, Stefan; Perneczky, Robert; Hakonarson, Hakon; Hampel, Harald; Von Arnim, Christine A.F.; Olsen, Jørgen H.; Van Deerlin, Vivianna M.; Al-Chalabi, Ammar; Toft, Mathias; Ritz, Beate & Bertram, Lars (2015). The role of TREM2 R47H as a risk factor for Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson’s disease. Alzheimer's & Dementia.  ISSN 1552-5260.  11(12), s 1407- 1416 . doi: 10.1016/j.jalz.2014.12.009
  • Pham, Uyen Ha Gia; Andersson, Stein; Toft, Mathias; Pripp, Are Hugo; Konglund, Ane; Dietrichs, Espen; Malt, Ulrik Fredrik; Skogseid, Inger Marie; Haraldsen, Ira Hebold & Solbakk, Anne-Kristin (2015). Self-Reported Executive Functioning in Everyday Life in Parkinson's Disease after Three Months of Subthalamic Deep Brain Stimulation. Parkinson's Disease.  ISSN 2090-8083.  2015:461453 . doi: 10.1155/2015/461453
  • Pham, Uyen Ha Gia; Solbakk, Anne-Kristin; Skogseid, Inger Marie; Toft, Mathias; Pripp, Are Hugo; Konglund, Ane; Andersson, Stein; Haraldsen, Ira Hebold; Aarsland, Dag; Dietrichs, Espen & Malt, Ulrik Fredrik (2015). Personality changes after deep brain stimulation in Parkinson's Disease. Parkinson's Disease.  ISSN 2090-8083.  2015:490507 . doi: 10.1155/2015/490507
  • Pihlstrøm, Lasse; Rengmark, Aina Sylvia Haugen; Bjørnarå, Kari Anne; Dizdar, Nil; Fardell, Camilla; Forsgren, Lars; Holmberg, Björn; Larsen, Jan Petter; Linder, Jan; Nissbrandt, Hans; Tysnes, Ole-Bjørn; Dietrichs, Espen & Toft, Mathias (2015). Fine mapping and resequencing of the PARK16 locus in Parkinson's disease. Journal of Human Genetics.  ISSN 1434-5161.  60(7), s 357- 362 . doi: 10.1038/jhg.2015.34
  • Wang, Lisa; Aasly, Jan; Annesi, Grazia; Bardien, Soraya; Bozi, Maria; Brice, Alexis; Carr, Jonathan; Chung, Sun J.; Clarke, Carl; Crosiers, David; Deutschländer, Angela; Eckstein, Gertrud; Farrer, Matthew J.; Goldwurm, Stefano; Garraux, Gaetan; Hadjigeorgiou, Georgios M.; Hicks, Andrew A.; Hattori, Nobutaka; Klein, Christine; Jeon, Beom; Kim, Yun Joong; Lesage, Suzanne; Lin, Juei-Jueng; Lynch, Timothy; Lichtner, Peter; Lang, Anthony E.; Mok, Vincent; Jasinska-Myga, Barbara; Mellick, George D.; Morrison, Karen E.; Opala, Grzegorz; Pihlstrøm, Lasse; Pramstaller, Peter P.; Park, Sung S.; Quattrone, Aldo; Rogaeva, Ekaterina; Ross, Owen A.; Stefanis, Leonidas; Stockton, Joanne D.; Silburn, Peter A.; Theuns, Jessie; Tan, Eng-King; Tomiyama, Hiroyuki; Toft, Mathias; Van Broeckhoven, Christine; Uitti, Ryan J.; Wirdefeldt, Karin; Wszolek, Zbigniew; Xiromerisiou, Georgia; Yueh, Kuo-Chu; Zhao, Yi; Gasser, Thomas; Maraganore, Demetrius M.; Krüger, Rejko & Sharma, Manu (2015). Large-scale assessment of polyglutamine repeat expansions in Parkinson disease. Neurology.  ISSN 0028-3878.  85(15), s 1283- 1292 . doi: 10.1212/WNL.0000000000002016
  • Bjerknes, Silje Kristin; Skogseid, Inger Marie; Sæhle, Terje; Dietrichs, Espen & Toft, Mathias (2014). Surgical site infections after deep brain stimulation surgery: Frequency, characteristics and management in a 10-year period. PLOS ONE.  ISSN 1932-6203.  9(8) . doi: 10.1371/journal.pone.0105288
  • Bjørnarå, Kari Anne; Dietrichs, Espen & Toft, Mathias (2014). Clinical features associated with sleep disturbances in Parkinson's disease. Clinical neurology and neurosurgery (Dutch-Flemish ed. Print).  ISSN 0303-8467.  124, s 37- 43 . doi: 10.1016/j.clineuro.2014.06.027
  • Børretzen, Mari Naumann; Bjerknes, Silje Kristin; Sæhle, Terje; Skjelland, Mona; Skogseid, Inger Marie; Toft, Mathias & Dietrichs, Espen (2014). Long-term follow-up of thalamic deep brain stimulation for essential tremor - patient satisfaction and mortality. BMC Neurology.  ISSN 1471-2377.  14(120) . doi: 10.1186/1471-2377-14-120
  • Koht, Jeanette; Rengmark, Aina Sylvia Haugen; Opladen, Thomas; Bjørnarå, Kari Anne; Selberg, Tore; Tallaksen, Chantal; Blau, N. & Toft, Mathias (2014). Clinical and genetic studies in a family with a novel mutation in the sepiapterin reductase gene. Acta Neurologica Scandinavica.  ISSN 0001-6314.  129(198), s 7- 12 . doi: 10.1111/ane.12230
  • Lilleeng, Bård Flattun; Brønnick, Kolbjørn S; Toft, Mathias; Dietrichs, Espen & Larsen, Jan Petter (2014). Progression and survival in Parkinson's disease with subthalamic nucleus stimulation. Acta Neurologica Scandinavica.  ISSN 0001-6314.  130(5), s 292- 298 . doi: 10.1111/ane.12224
  • Pihlstrøm, Lasse; Rengmark, Aina Sylvia Haugen; Bjørnarå, Kari Anne & Toft, Mathias (2014). Effective variant detection by targeted deep sequencing of DNA pools: An example from parkinson's disease. Annals of Human Genetics.  ISSN 0003-4800.  78(3), s 243- 252 . doi: 10.1111/ahg.12060
  • Toft, Mathias (2014). Advances in genetic diagnosis of neurological disorders. Acta Neurologica Scandinavica.  ISSN 0001-6314.  129(198), s 20- 25 . doi: 10.1111/ane.12232
  • Bjørnarå, Kari Anne; Dietrichs, Espen & Toft, Mathias (2013). REM sleep behavior disorder in Parkinson's disease - Is there a gender difference?. Parkinsonism & Related Disorders.  ISSN 1353-8020.  19(1), s 120- 122 . doi: 10.1016/j.parkreldis.2012.05.027
  • Karlsson, Magdalena Kauczynska; Sharma, Praveen; Aasly, Jan; Toft, Mathias; Skogar, Ørjan; Sæbø, Solve & Lönneborg, Anders (2013). Found in transcription: Accurate Parkinson’s disease classification in peripheral blood. Journal of Parkinson's Disease.  ISSN 1877-7171.  3(1), s 19- 29 . doi: 10.3233/JPD-120159
  • Pihlstrøm, Lasse; Axelsson, Gunnar; Bjørnarå, Kari Anne; Dizdar, Nil; Fardell, Camilla; Forsgren, Lars; Holmberg, Björn; Larsen, Jan Petter; Linder, Jan; Nissbrandt, Hans; Tysnes, Ole-Bjørn; Öhman, Eilert; Dietrichs, Espen & Toft, Mathias (2013). Supportive evidence for 11 loci from genome-wide association studies in Parkinson's disease. Neurobiology of Aging.  ISSN 0197-4580.  34(6) . doi: 10.1016/j.neurobiolaging.2012.10.019
  • Pihlstrøm, Lasse & Toft, Mathias (2011). Genetic variability in SNCA and Parkinson's disease. Neurogenetics.  ISSN 1364-6745.  12(4), s 283- 293 . doi: 10.1007/s10048-011-0292-7 Vis sammendrag
  • Pihlstrøm, Lasse & Toft, Mathias (2011). Parkinson’s Disease: What Remains of the ‘‘Missing Heritability’’?. Movement Disorders.  ISSN 0885-3185.  26(11), s 1971- 1973 . doi: 10.1002/mds.23898
  • Toft, Mathias (2011). The Wilson films - MS Tremor. Movement Disorders.  ISSN 0885-3185.  26(14), s 2471- 2472 . doi: 10.1002/mds.24010 Vis sammendrag
  • Toft, Mathias & Dietrichs, Espen (2011). Aggravated stuttering following subthalamic deep brain stimulation in Parkinson's disease - two cases. BMC Neurology.  ISSN 1471-2377.  11 . doi: 10.1186/1471-2377-11-44
  • Toft, Mathias; Lilleeng, Bård; Ramm-Pettersen, Jon-Terje; Skogseid, Inger Marie; Gundersen, Vidar; Gerdts, Reno; Pedersen, Lena; Skjelland, Mona; Røste, Geir Ketil & Dietrichs, Espen (2011). Long-Term Efficacy and Mortality in Parkinson's Disease Patients Treated with Subthalamic Stimulation. Movement Disorders.  ISSN 0885-3185.  26(10), s 1931- 1934 . doi: 10.1002/mds.23817
  • Aasly, Jan; Vilarino-Guell, C; Dachsel, JC; Webber, PJ; West, AB; Haugarvoll, Kristoffer; Johansen, Krisztina Kunszt; Toft, Mathias; Nutt, JG; Payami, H; Kachergus, J; Lincoln, SJ; Felic, Amela; Wider, C; Soto-Ortolaza, AI; Cobb, SA; White, Linda; Ross, OA & Farrer, MJ (2010). Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease. Movement Disorders.  ISSN 0885-3185.  25(13), s 2156- 2163 . doi: 10.1002/mds.23265
  • Haugarvoll, Kristoffer; Toft, Mathias; Skipper, L; Heckman, MG; Crook, JE; Soto, A; Ross, OA; Hulihan, MM; Kachergus, JM; Sando, Sigrid Botne; White, Linda; Lynch, T; Gibson, JM; Uitti, RJ; Wszolek, ZK; Aasly, Jan & Farrer, MJ (2009). Fine-mapping and candidate gene investigation within the PARK 10 locus. European Journal of Human Genetics.  ISSN 1018-4813.  17(3), s 336- 343 . doi: 10.1038/ejhg.2008.187
  • Myhre, Ronny; Toft, Mathias; Kachergus, J; Hulihan, MM; Aasly, Jan; Klungland, Helge & Farrer, MJ (2008). Multiple alpha-synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population. Acta Neurologica Scandinavica.  ISSN 0001-6314.  118(5), s 320- 327
  • Haugarvoll, Kristoffer; Toft, Mathias; Ross, OA; Stone, JT; Heckman, MG; White, Linda; Lynch, T; Gibson, JM; Wszolek, ZK; Uitti, RJ; Aasly, Jan & Farrer, MJ (2007). ELAVL4, PARK10, and the Celts. Movement Disorders.  ISSN 0885-3185.  22(4), s 585- 587 . doi: 10.1002/mds.21336
  • Haugarvoll, Kristoffer; Toft, Mathias; Ross, OA; White, Linda; Aasly, Jan & Farrer, MJ (2007). Variants in the LRRK1 gene and susceptibility to Parkinson's disease in Norway. Neuroscience Letters.  ISSN 0304-3940.  416(3), s 299- 301 . doi: 10.1016/j.neulet.2007.02.020
  • Toft, Mathias; Haugarvoll, Kristoffer; Ross, OA; Farrer, MJ & Aasly, Jan (2007). LRRK2 and Parkinson's disease in Norway. Acta Neurologica Scandinavica.  ISSN 0001-6314.  115, s 72- 75
  • Toft, Mathias; Mata, IF; Ross, OA; Kachergus, J; Hulihan, MM; Haugarvoll, Kristoffer; Stone, JT; Blazquez, M; Gibson, JM; Aasly, Jan; White, Linda; Lynch, T; Adler, CH; Gwinn-Hardy, K & Farrer, MJ (2007). Pathogenicity of the Lrrk2 R1514Q substitution in Parkinson's disease. Movement Disorders.  ISSN 0885-3185.  22(3), s 389- 392 . doi: 10.1002/mds.21217
  • Toft, Mathias; Myhre, Ronny; Pielsticker, L; White, Linda; Aasly, Jan & Farrer, MJ (2007). PINK1 mutation heterozygosity and the risk of Parkinson's disease. Journal of Neurology, Neurosurgery and Psychiatry.  ISSN 0022-3050.  78(1), s 82- 84 . doi: 10.1136/jnnp.2006.097840
  • White, Linda R.; Toft, Mathias; Kvam, Sylvia Nome; Farrer, MJ & Aasly, Jan (2007). MAPK-pathway activity, Lrrk2 G2019S, and Parkinson's disease. Journal of Neuroscience Research.  ISSN 0360-4012.  85(6), s 1288- 1294 . doi: 10.1002/jnr.21240
  • Toft, Mathias; Pielsticker, L; Ross, OA; Aasly, Jan & Farrer, MJ (2006). Glucocerebrosidase gene mutations and Parkinson disease in the Norwegian population. Neurology.  ISSN 0028-3878.  66
  • Gosal, D; Ross, OA & Toft, Mathias (2006). Parkinson's disease: the genetics of a heterogeneous disorder. European Journal of Neurology.  ISSN 1351-5101.  13
  • Aasly, Jan; Toft, Harald M.Strøm; Fernandez-Mata, I; Kachergus, J; Hulihan, M; White, Linda & Farrer, M (2005). Clinical features of LRRK2-associated Parkinson's disease in Central Norway. Annals of Neurology.  ISSN 0364-5134.  57
  • Kachergus, J; Mata, IF; Hulihan, M; Taylor, JP; Lincoln, S; Aasly, Jan; Gibson, JM; Ross, OA; Lynch, T; Wiley, J; Payami, H; Nutt, J; Maraganore, DM; Czyzewski, K; Styczynska, M; Wszolek, ZK; Farrer, MJ & Toft, Mathias (2005). Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism; evidence for a common founder across European populations. American Journal of Human Genetics.  ISSN 0002-9297.  76(4), s 672- 680 Vis sammendrag
  • Myhre, Ronny & Toft, Mathias (2005). Genetiske studier av Parkinsons sykdom. NBS-nytt.  ISSN 0801-3535.  (1), s 42- 43
  • Toft, Mathias (2005). Genetics of Parkinson's disease, In N Galvez-Jimenez (ed.),  The scientific basis for the treatment of Parkinson’s disease.  Taylor & Francis.  ISBN 1-84214-182-1.  Chapter 7.  s 121 - 130
  • Toft, Mathias; Aasly, Jan; Bisceglio, G; Adler, CH; Uitti, RJ; Krygowska-Wajs, A; Lynch, T; Wszolek, ZK & Farrer, MJ (2005). Parkinsonism, FXTAS, and FMR1 premutations. Movement Disorders.  ISSN 0885-3185.  20(2), s 230- 233 Vis sammendrag
  • Toft, Mathias; Sando, Sigrid Botne; Melquist, S.; Ross, O.A.; White, Linda; Aasly, Jan & Farrer, MJ (2005). LRRK2 mutations are not common in Alzheimer's disease. Mechanisms of Ageing and Development.  ISSN 0047-6374.  126(11), s 1201- 1205 Vis sammendrag
  • haugen, tonje; Toft, Harald M.Strøm; Müller, Clemens R & Aasly, Jan (2005). Malign hypertermi - en arvelig og potensielt livstruende tilstand. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  (Årg. 125, nr 20), s 2792- 2794
  • Skipper, L; Wilkes, K; Toft, Mathias; Baker, M; Lincoln, S; Hulihan, M; Ross, OA; Hutton, M.; Aasly, Jan & Farrer, M (2004). Linkage disequilibrium and association of MAPT H1 in Parkinson disease. American Journal of Human Genetics.  ISSN 0002-9297.  75(4), s 669- 677 Vis sammendrag
  • Toft, Mathias & Aasly, Jan (2004). Genetikk ved Parkinsons sykdom. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  124, s 922- 924

Se alle arbeider i Cristin

  • Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Bahrami, Shahram; Broce, Iris J.; Tesli, Martin Steen; Frei, Oleksandr; Wirgenes, Katrine Verena; O`Connell, Kevin; Krull, Florian; Bettella, Francesco; Steen, Nils Eiel; Sugrue, Leo P.; Wang, Yunpeng; Svenningsson, Per; Sharma, Manu; Pihlstrøm, Lasse; Toft, H. Mathias S.; O’Donovan, Michael; Djurovic, Srdjan; Desikan, Rahul S; Dale, Anders M. & Andreassen, Ole Andreas (2020). Genome-wide Association Analysis of Parkinson’s Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci. Biological Psychiatry.  ISSN 0006-3223. . doi: 10.1016/j.biopsych.2020.01.026
  • Iqbal, Zafar; Pihlstrøm, Lasse; Rengmark, Aina Sylvia Haugen; Henriksen, Sandra Pilar; Linder, Jan; Forsgren, Lars & Toft, Mathias (2016). Rare variants in dementia genes and Parkinson's disease. European Journal of Human Genetics.  ISSN 1018-4813.  24(12), s 1661- 1662 . doi: 10.1038/ejhg.2016.79
  • Rengmark, Aina Sylvia Haugen; Pihlstrøm, Lasse; Linder, Jan; Forsgren, Lars & Toft, Mathias (2016). Low frequency of GCH1 and TH mutations in Parkinson's disease. Parkinsonism & Related Disorders.  ISSN 1353-8020.  29, s 109- 111 . doi: 10.1016/j.parkreldis.2016.05.010
  • Toft, Mathias & Ross, Owen A. (2016). Exome variant mining in familial Parkinson disease will replication find the gold?. JAMA Neurology.  ISSN 2168-6149.  73(1), s 21- 22 . doi: 10.1001/jamaneurol.2015.3536
  • Iqbal, Zafar & Toft, Mathias (2015). CHCHD2 and Parkinson's disease. Lancet Neurology.  ISSN 1474-4422.  14(7), s 680- 681 . doi: 10.1016/S1474-4422(15)00096-4
  • Pihlstrøm, Lasse; Berge, Victoria; Rengmark, Aina Sylvia Haugen & Toft, Mathias (2015). Parkinson's disease correlates with promoter methylation in the α-synuclein gene. Movement Disorders.  ISSN 0885-3185.  30(4), s 577- 580 . doi: 10.1002/mds.26073
  • Pihlstrøm, Lasse & Toft, Mathias (2015). Cumulative genetic risk and age at onset in Parkinson's disease. Movement Disorders.  ISSN 0885-3185.  30(12), s 1712- 1713 . doi: 10.1002/mds.26366
  • Toft, Mathias & Dietrichs, Espen (2014). Medication costs following subthalamic nucleus deep brain stimulation for Parkinson's disease. Movement Disorders.  ISSN 0885-3185.  29(2), s 275- 276 . doi: 10.1002/mds.25504
  • Pihlstrøm, Lasse; Bjornara, KA; Dizdar, N; Fardell, C; Forsgren, L; Holmberg, B; Larsen, Jan Petter; Linder, J; Nissbrandt, H; Tysnes, Ole-Bjørn; Dietrichs, Espen & Toft, Mathias (2012). A Scandinavian multi-centre study replicates 11 susceptibility loci from genome-wide association studies in Parkinson's disease. European Journal of Neurology.  ISSN 1351-5101.  19, s 40- 40
  • Toft, Mathias (2011). Dopaminergic Neurons Generated Directly From Human Fibroblasts. Movement Disorders.  ISSN 0885-3185.  26(11), s 1975- 1975 . doi: 10.1002/mds.23938
  • Toft, Mathias (2011). International Consortium Identifies New Genetic Risk Factors for Parkinson's Disease. Movement Disorders.  ISSN 0885-3185.  26(4), s 606- 606 . doi: 10.1002/mds.23725
  • Toft, Mathias & Dietrichs, Espen (2011). Levodopa-Responsive Parkinsonism in Probable Extrapontine Myelinolysis of the Mesencephalon. Movement Disorders.  ISSN 0885-3185.  26(12), s 2180- 2181 . doi: 10.1002/mds.23876
  • Egebakken, E.C.; Vilming, S; Toft, Mathias & LUNDQVIST, CHRISTOFER (2010). Function and quality-of-life of fluctuating PD patients on DBS, intraduodenal levodopa and per-oral medication. European Journal of Neurology.  ISSN 1351-5101.  17, s 394- 394
  • Toft, Mathias & White, Linda (2007). Genetic studies of LRRK2 and PINK1 in Parkinson's disease.
  • White, Linda; Toft, Mathias; Farrer, MJ; Kvam, Sylvia Nome & Aasly, Jan (2007). Leukocyte Mapk activity associated with the LRRK2 G2019S mutation and Parkinson's disease. Neurodegenerative Diseases.  ISSN 1660-2854.  4, s 137
  • White, Linda; Kvam, Sylvia Nome; Toft, Mathias; Farrer, MJ & Aasly, Jan (2006). Leukocyte MAPK activity associated with the LRRK2 G2019S mutation and Parkinson's disease.
  • White, Linda; Toft, Mathias; Kvam, Sylvia Nome & Aasly, Jan (2006). Cellesignalisering, LRRK2 G2019S og Parkinsons sykdom. Vis sammendrag
  • Farrer, MJ; Haugarvoll, K; Ross, OA; Stone, JT; Whittle, AJ; Lincoln, SJ; Hulihan, MM; Heckman, MG; White, Linda; Aasly, Jan; Gibson, JM; Gosal, D; Lynch, T; Wszolek, ZK; Uitti, RJ & Toft, Mathias (2006). Genomewide association, Parkinson disease, and PARK10. American Journal of Human Genetics.  ISSN 0002-9297.  78
  • Aasly, Jan; Farrer, M.; Toft, Mathias; Kvam, Sylvia Nome & White, Linda (2005). Why does a mutation in the LRRK2 gene (G2019S) lead to Parkinson's disease? Microarray Gene Expression analysis: power and potential of standardisation.
  • Aasly, Jan; Toft, Mathias; Mata, IF; Kachergus, J; Hulihan, M & Farrer, MJ (2005). The Clinical Features and Frequency of LRRK2 Associated Parkinson's Disease in Central Norway. Neurology.  ISSN 0028-3878.  64(6), s A148
  • Aasly, Jan; Toft, Mathias; Mata, IF; Kachergus, J; Hulihan, M & Farrer, MJ (2005). The Clinical Features and Frequency of LRRK2 Associated Parkinson's Disease in Central Norway.
  • Aasly, Jan; Toft, Mathias; Mata, IF; White, Linda; Hulihan, M. & Farrer, M. (2005). Family aggregation and geographical clustering of LRRK2 associated Parkinson's disease in central Norway.
  • Aasly, Jan; Toft, Mathias; Mata, IF; White, Linda; Hulihan, M & Farrer, MJ (2005). Family aggregation and geographical clustering of LRRK2 associated Parkinson's disease in central Norway. Movement Disorders.  ISSN 0885-3185.  20, s S118
  • Toft, Mathias; Kachergus, J; Mata, IF; Hulihan, M.; Aasly, Jan & Farrer, M. (2005). A novel LRRK2 mutation is a common cause of autosomal dominant parkinsonism in families from several european populations.
  • Toft, Mathias; Kachergus, J; Mata, IF; Hulihan, M; Aasly, Jan & Farrer, MJ (2005). A novel LRRK2 mutation is a common cause of autosomal dominant parkinsonism in families from several European populations. Movement Disorders.  ISSN 0885-3185.  20, s S37
  • Toft, Mathias; Mata, IF; Kachergus, J; Hulihan, M; Aasly, Jan; Gibson, M; Ross, O.A.; Lynch, T; Wszolek, ZK; Maraganore, DM; Czyzewski, K; Styczynska, M; Pyami, H; Nutt, J & Farrer, MJ (2005). Identification of a Novel LRRK2 Mutation, Linked to Autosomal Domimnant Parkinsonism in Families from Several European Populations; Evidence for a Common Founder. Neurology.  ISSN 0028-3878.  64(6), s A147
  • Toft, Mathias; Mata, IF; Kachergus, J; Hulihan, M; Aasly, Jan; Gibson, M; Ross, O.A.; Lynch, T; Wszolek, ZK; Maraganore, DM; Czyzewski, K; Styczynska, M; Pyami, H; Nutt, J & Farrer, MJ (2005). Identification of a Novel LRRK2 Mutation, Linked to Autosomal Dominant Parkinsonism in Families from Several European Populations; Evidence for a Common Founder.
  • Toft, Mathias; Pielsticker, L.; Aasly, Jan & Farrer, M (2005). Glucocerebrosidase gene mutations are not associated with Parkinson's disease in the Norwegian population. Movement Disorders.  ISSN 0885-3185.  20, s S38
  • Toft, Mathias; Pielsticker, L.; Aasly, Jan & Farrer, M. (2005). Glucocerebrosidase gene mutations are not associated with Parkinson's disease in the Norwegian population.
  • Toft, Mathias; Pielsticker, L.; Mata, IF; Stone, J.T.; Aasly, Jan & Farrer, M. (2005). PINK1 mutations in early-onset and recessive Parkinson's disease in Norway.
  • Toft, Mathias; Pielstiecker, L; Mata, IF; Stone, J.T.; Aasly, Jan & Farrer, MJ (2005). PINK1 mutations in early-onset and recessive Parkinson's disease in Norway. Movement Disorders.  ISSN 0885-3185.  20, s S35
  • Toft, Mathias; White, Linda & Aasly, J (2005). LRRK2-assosiert Parkinsons sykdom i Norge. Vis sammendrag
  • Toft, Mathias (2004). Mapping a gene for Parkinson's disease in Norway.
  • Toft, Mathias; Skipper, L; Hulihan, M.; Aasly, Jan & Farrer, M. (2004). Mapping a gene for Parkinson's disease in Norway. Movement Disorders.  ISSN 0885-3185.  19, s 360
  • Toft, Mathias; Skipper, L; Wilkes, K; Lincoln, S; Aasly, Jan & Farrer, M (2003). Mapping the genetic architecture of Tau H1 in neurodegeneration.

Se alle arbeider i Cristin

Publisert 8. nov. 2017 13:28 - Sist endret 8. nov. 2017 13:28

Forskergrupper