Kurt Allen Krobert

Bilde av Kurt Allen Krobert
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Telefon +47 22840264
Brukernavn
Besøksadresse Sognsvannsveien 20 Rikshospitalet 0372 OSLO
Postadresse Postboks 1057 Blindern 0316 OSLO

Publikasjoner

  • Cosson, Marie-Victoire; Hiis, Halvard Gautefall; Moltzau, Lise Roman; Levy, Finn Olav & Krobert, Kurt Allen (2019). Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the ? <sub>1</sub> -adrenoceptor-mediated inotropic response. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  131, s 132- 145 . doi: 10.1016/j.yjmcc.2019.04.017
  • Melsom, Elin Maria Caroline Bull; Cosson, Marie-Victoire; Ørstavik, Øivind; Lai, Ngai Chin; Hammond, H. Kirk; Osnes, Jan-Bjørn; Skomedal, Tor; Nikolaev, Viacheslav; Levy, Finn Olav & Krobert, Kurt Allen (2019). Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6. PLOS ONE.  ISSN 1932-6203.  14:e021810(6), s 1- 19 . doi: 10.1371/journal.pone.0218110 Fulltekst i vitenarkiv.
  • Hiis, Halvard Gautefall; Cosson, Marie-Victoire; Dahl, Christen Peder; Fiane, Arnt E; Levy, Finn Olav; Andersen, Geir Øystein & Krobert, Kurt Allen (2018). Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  315(5), s H1137- H1147 . doi: 10.1152/ajpheart.00208.2018 Fulltekst i vitenarkiv.
  • Andressen, Kjetil Wessel; Ulsund, Andrea Hembre; Krobert, Kurt Allen; Lohse, Martin J.; Bünemann, Moritz & Levy, Finn Olav (2017). Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gαs upon receptor activation. The FASEB Journal.  ISSN 0892-6638.  32(2), s 1059- 1069 . doi: 10.1096/fj.201700486R
  • Braadland, Peder; Grytli, Helene Hartvedt; Ramberg, Håkon Andre; Katz, Betina; Kellmann, Ralf; Gauthier-Landry, louis; Fazli, Ladan; Krobert, Kurt Allen; Wang, Wanzhong; Levy, Finn Olav; Bjartell, Anders; Berge, Viktor; Rennie, Paul S.; Mellgren, Gunnar; Mælandsmo, Gunhild; Svindland, Aud; barbier, olivier & Tasken, Kristin Austlid (2016). Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism. OncoTarget.  ISSN 1949-2553.  7(2), s 1878- 1894 . doi: 10.18632/oncotarget.6479 Fulltekst i vitenarkiv. Vis sammendrag
  • Andressen, Kjetil Wessel; Manfra, Ornella; Brevik, Christian Hellesylt; Ulsund, Andrea Hembre; Vanhoenacker, Peter; Levy, Finn Olav & Krobert, Kurt Allen (2015). The atypical antipsychotics clozapine and olanzapine promote down-regulation and display functional selectivity at human 5-HT7 receptors. British Journal of Pharmacology.  ISSN 0007-1188.  172(15), s 3846- 3860 . doi: 10.1111/bph.13169
  • Impellizzeri, Agata Antonina Rita; Pappalardo, Matteo; Basile, Livia; Manfra, Ornella; Andressen, Kjetil Wessel; Krobert, Kurt Allen; Messina, Angela; Levy, Finn Olav & Guccione, Salvatore (2015). Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis. Frontiers in Behavioral Neuroscience.  ISSN 1662-5153.  9(MAY) . doi: 10.3389/fnbeh.2015.00092 Fulltekst i vitenarkiv.
  • Ørstavik, Øivind; Manfra, Ornella; Andressen, Kjetil Wessel; Andersen, Geir Øystein; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav & Krobert, Kurt Allen (2015). The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium. PLOS ONE.  ISSN 1932-6203.  10(3) . doi: 10.1371/journal.pone.0115547 Fulltekst i vitenarkiv.
  • Melsom, Elin Maria Caroline Bull; Hussain, Rizwan; Ørstavik, Øivind; Aronsen, Jan Magnus; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav & Krobert, Kurt Allen (2014). Non-classical regulation of β1- and β2 adrenoceptor- mediated inotropic responses in rat ventricle by the G protein Gi. Naunyn-Schmiedeberg's Archives of Pharmacology.  ISSN 0028-1298.  387(12), s 1177- 1186 . doi: 10.1007/s00210-014-1036-7
  • Melsom, Elin Maria Caroline Bull; Ørstavik, Øivind; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2014). Gi proteins regulate adenylyl cyclase activity independent of receptor activation. PLoS Medicine.  ISSN 1549-1277.  9:e0106608(9) . doi: 10.1371/journal.pone.0106608 Fulltekst i vitenarkiv.
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Krobert, Kurt Allen; Edvardsen, Thor; Moe, Ingvild Tronstad; Hagelin, Else Marie Valbjørn; Sagave, Julia Fritzi; Valen, Guro; Levy, Finn Olav; Osnes, Jan-Bjørn; Skomedal, Tor & Attramadal, Håvard (2013). Connective Tissue Growth Factor/CCN2 Attenuates beta-Adrenergic Receptor Responsiveness and Cardiotoxicity by Induction of G Protein-Coupled Receptor Kinase-5 in Cardiomyocytes. Molecular Pharmacology.  ISSN 0026-895X.  84(3), s 372- 383 . doi: 10.1124/mol.113.087312
  • Hussain, Rizwan; Aronsen, Jan Magnus; Afzal, Faraz; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2013). The functional activity of inhibitory G protein (Gi) is not increased in failing heart ventricle. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  56, s 129- 138 . doi: 10.1016/j.yjmcc.2012.11.015
  • Levay, Magdolna; Krobert, Kurt Allen; Wittig, Karola; Voigt, Niels; Bermudez, Marcel; Wolber, Gerhard; Dobrev, Dobromir; Levy, Finn Olav & Wieland, Thomas (2013). NSC23766, a widely used inhibitor of Rac1 activation, additionally acts as a competitive antagonist at muscarinic acetylcholine receptors. Journal of Pharmacology and Experimental Therapeutics.  ISSN 0022-3565.  347(1), s 69- 79 . doi: 10.1124/jpet.113.207266
  • Molenaar, Peter; Christ, Torsten; Hussain, Rizwan; Engel, Andreas; Berk, Emanuel; Gillette, Katherine T.; Chen, Lu; Galindo-Tovar, Alejandro; Krobert, Kurt Allen; Ravens, Ursula; Levy, Finn Olav & Kaumann, Alberto Julio (2013). PDE3, but not PDE4, reduces beta 1- and beta 2-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients. British Journal of Pharmacology.  ISSN 0007-1188.  169(3), s 528- 538 . doi: 10.1111/bph.12167
  • Riise, Jon; Nguyen, Hong Cam Thi; Hussain, Rizwan; Dahl, Christen Peder; Ege, Maren Stapnes; Osnes, Jan-Bjørn; Skomedal, Tor; Sandnes, Dagny Lise; Levy, Finn Olav & Krobert, Kurt Allen (2012). Prostanoid-mediated inotropic responses are attenuated in failing human and rat ventricular myocardium. European Journal of Pharmacology.  ISSN 0014-2999.  686(1-3), s 66- 73 . doi: 10.1016/j.ejphar.2012.04.022
  • Riise, Jon; Ørstavik, Øivind; Qvigstad, Eirik; Dahl, Christen Peder; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2012). Prostaglandin E-1 facilitates inotropic effects of 5-HT4 serotonin receptors and beta-adrenoceptors in failing human heart. Basic Research in Cardiology.  ISSN 0300-8428.  107(5) . doi: 10.1007/s00395-012-0295-z
  • von Lueder, Thomas Gero; Gravning, Jørgen A.; How, Ole-Jakob; Vinge, Leif Erik; Ahmed, Muhammad Shakil; Krobert, Kurt Allen; Levy, Finn Olav; Larsen, Terje; Smiseth, Otto A.; Aasum, Ellen & Attramadal, Håvard (2012). Cardiomyocyte-restricted inhibition of G protein-coupled receptor kinase-3 attenuates cardiac dysfunction after chronic pressure overload. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  303(1), s H66- H74 . doi: 10.1152/ajpheart.00724.2011
  • Hussain, Rizwan; Afzal, Faraz; Mørk, Halvor Kjeang; Aronsen, Jan Magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2011). Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle. British Journal of Pharmacology.  ISSN 0007-1188.  162(4), s 908- 916 . doi: 10.1111/j.1476-5381.2010.01097.x
  • Brudeli, Bjarne; Moltzau, Lise Roman; Andressen, Kjetil Wessel; Krobert, Kurt Allen; Klaveness, Jo & Levy, Finn Olav (2010). Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists. Bioorganic & Medicinal Chemistry.  ISSN 0968-0896.  18(24), s 8600- 8613 . doi: 10.1016/j.bmc.2010.10.011
  • Hussain, RI; Qvigstad, Eirik; Birkeland, Jon Arne; Eikemo, Hilde; Glende, A; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav & Krobert, Kurt Allen (2009). Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. British Journal of Pharmacology.  ISSN 0007-1188.  156(4), s 575- 586 . doi: 10.1111/j.1476-5381.2009.00016.x
  • Hussain, Rizwan; Qvigstad, Erik; Birkeland, Jon Arne; Eikemo, Hilde; Glende, A; Sjaastad, Ivar; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav & Krobert, Kurt Allen (2009). Activation of muscarinic receptors elicits inotropic responses in ventricular muscle from rats with heart failure through myosin light chain phosphorylation. British Journal of Pharmacology.  ISSN 0007-1188.  156(4), s 575- 586 . doi: 10.1111/j.1750-3639.2009.00016.x Vis sammendrag
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin; Florholmen, Geir; Ruud Larsen, Ann-Kristin; Levy, Finn Olav; Tasken, Kjetil; Skjønsberg, Ole Henning & Christensen, Geir Arve (2008). Diastolic dysfunction in alveolar hypoxia: a role for interleukin-18-mediated increase in protein phosphatase 2A. Cardiovascular Research (CVR).  ISSN 0008-6363.  80(1), s 47- 54 . doi: 10.1093/cvr/cvn180
  • Levy, Finn Olav; Qvigstad, Eirik; Krobert, Kurt Allen; Skomedal, Tor & Osnes, Jan-Bjørn (2008). Effects of serotonin in failing cardiac ventricle: Signalling mechanisms and potential therapeutic implications. Neuropharmacology.  ISSN 0028-3908.  55(6), s 1066- 1071 . doi: 10.1016/j.neuropharm.2008.07.010
  • Ramberg, Håkon; Eide, Turid; Krobert, Kurt Allen; Levy, Finn Olav; Dizeyi, N; Bjartell, AS; Abrahamsson, PA & Tasken, Kristin Austlid (2008). Hormonal regulation of beta(2)-adrenergic receptor level in prostate cancer. The Prostate.  ISSN 0270-4137.  68(10), s 1133- 1142 . doi: 10.1002/pros.20778
  • Riise, J; Nguyen, Hong Cam Thi; Qvigstad, Eirik; Sandnes, Dagny Lise; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2008). Prostanoid F receptors elicit an inotropic effect in rat left ventricle by enhancing myosin light chain phosphorylation. Cardiovascular Research (CVR).  ISSN 0008-6363.  80(3), s 407- 415 . doi: 10.1093/cvr/cvn216
  • Birkeland, Jon Arne; Sjaastad, Ivar; Brattelid, Trond; Qvigstad, Eirik; Moberg, Enrica Ratti; Krobert, Kurt Allen; Bjørnerheim, Reidar; Skomedal, Tor; Sejersted, Ole M; Osnes, Jan-Bjørn & Levy, Finn Olav (2007). Effects of treatment with a 5-HT4 receptor antagonist in heart failure. British Journal of Pharmacology.  ISSN 0007-1188.  150, s 143- 152 . doi: 10.1038/sj.bjp.0706966
  • Brattelid, Trond; Qvigstad, E; Birkeland, Jan Magne; Birkeland, Jon Arne; Swift, F; Bekkevold, SVS; Krobert, KA; Sejersted, Ole M.; Skomedal, T; Osnes, JB; Levy, F. & Sjaastad, I (2007). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  43, s 767- 779 . doi: 10.1016/j.yjmcc.2007.08.019
  • Brattelid, Trond; Tveit, Kristine; Birkeland, Jon Arne; Sjaastad, Ivar; Qvigstad, Eirik; Krobert, Kurt Allen; Rizwan, Hussain; Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2007). Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure : A quantitative RT-PCR study and the question of normalisation. Basic Research in Cardiology.  ISSN 0300-8428.  102, s 198- 208 . doi: 10.1007/s00395-007-0648-1
  • Andressen, Kjetil Wessel; Norum, Jens Henrik; Levy, Finn Olav & Krobert, Kurt Allen (2006). Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT7 receptor expression. Molecular Pharmacology.  ISSN 0026-895X.  69, s 207- 215
  • Krobert, Kurt Allen; Andressen, Kjetil Wessel & Levy, Finn Olav (2006). Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT7 serotonin receptor. European Journal of Pharmacology.  ISSN 0014-2999.  532, s 1- 10
  • Larsen, Karl-Otto; Sjaastad, Ivar; Svindland, A; Krobert, Kurt Allen; Skjønsberg, Ole Henning & Christensen, Geir Arve (2006). Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  291, s H507- H516
  • Krobert, Kurt Allen; Brattelid, Trond; Levy, Finn Olav & Kaumann, Alberto Julio (2005). Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants. Naunyn-Schmiedeberg's Archives of Pharmacology.  ISSN 0028-1298.  371(6), s 471- 479 . doi: 16012870 Vis sammendrag
  • Qvigstad, Eirik; Brattelid, Trond; Sjaastad, Ivar; Molenaar, P.; Birkeland, Jon Arne; Andressen, Kjetil Wessel; Krobert, Kurt Allen; Sejersted, Ole M; Skomedal, Tor; Osnes, Jan-Bjørn; Kaumann, Alberto Julio & Levy, Finn Olav (2005). Rationale for treatment of heart failure by blockade of ventricular serotonin receptors appearing in heart failure, In  Proceedings of the 25th European Section Meeting, International Society for Heart Research, Tromsø, Norway, June 21-25, 2005.  Medimond.  ISBN 88-7587-164-7.  Invited Lectures.  s 7 - 12 Vis sammendrag
  • Øie, Erik; Vinge, Leif Erik; Andersen, Geir Øystein; Yndestad, Arne; Krobert, Kurt Allen; Sandberg, Cecilie; Ahmed, Muhammad Shakil; Haug, Terje; Levy, Finn Olav; Skomedal, Tor & Attramadal, Håvard (2005). RAMP2 and RAMP3 rnRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  38, s 145- 151
  • Qvigstad, Eirik; Brattelid, Trond; Sjaastad, Ivar; Andressen, Kjetil Wessel; Krobert, Kurt Allen; Birkeland, Jon Arne; Sejersted, Ole M; Kaumann, Alberto Julio; Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2005). Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure. Cardiovascular Research (CVR).  ISSN 0008-6363.  65 Vis sammendrag
  • Qvigstad, Eirik; Sjaastad, Ivar; Brattelid, Trond; Nunn, Caroline; Swift, Fredrik; Birkeland, Jon Arne; Krobert, Kurt Allen; Andersen, Geir Øystein; Sejersted, Ole M; Osnes, Jan-Bjørn; Levy, Finn Olav & Skomedal, Tor (2005). Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart. Circulation Research.  ISSN 0009-7330.  97, s 268- 276
  • Brattelid, Trond; Kvingedal, Ane Marit; Krobert, Kurt Allen; Andressen, Kjetil Wessel; Bach, Trond; Hystad, Marit Elise; Kaumann, Alberto Julio & Levy, Finn Olav (2004). Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i). Naunyn-Schmiedeberg's Archives of Pharmacology.  ISSN 0028-1298.  369(6), s 616- 628 . doi: 15118808 Vis sammendrag

Se alle arbeider i Cristin

  • Melsom, CB; Hussain, Rizwan; Aronsen, Jan Magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav & Krobert, Kurt Allen (2011). The role of inhibitory G protein upon beta-adrenoceptor-mediated signalling and inotropic responses in normal and failing rat heart left ventricle: Functional evidence of "tonic" Gi activation.
  • Gravning, Jørgen A.; Ahmed, Muhammad Shakil; Qvigstad, Eirik; Sagave, Julia Fritzi; Krobert, Kurt Allen; Edvardsen, Thor; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn & Attramadal, Håvard (2009). CCN2/CTGF - Connective Tissue Growth Factor - Reduces beta-Adrenergic Receptor Responsiveness and Catecholamine-Induced Cardiotoxicity by Upregulation of Cardiac Myocyte G Protein-Coupled Receptor Kinase-5. Circulation.  ISSN 0009-7322.  120(18), s S720- S720
  • Krobert, Kurt Allen; Hussain, Rizwan; Afzal, Faraz; Aronsen, Jon magnus; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor & Levy, Finn Olav (2009). Inreased Gi activity does not contribute to the reduced beta-adrenergic inotropic effect in failing rat ventricle but Gi acts as a tonic brake on basal adenylyl cyclase activity.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin; Florholmen, Geir; Larsen, A; Levy, Finn Olav; Tasken, Kjetil; Skjønsberg, Ole Henning & Christensen, Geir Arve (2009). Increased circulating IL-18; a possible mechanism for hypoxia-induced cardiac dysfunction.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin; Florholmen, Geir; Levy, Finn Olav; Tasken, Kjetil; Christensen, Geir Arve & Skjønsberg, Ole Henning (2009). Mechanisms for cardiac dysfunction in COPD and respiratory failure. Respiratory Medicine.  ISSN 0954-6111.  103, s S6- S7
  • Gravning, Jørgen Amundsen; Ahmed, Muhammad Shakil; Qvigstad, Erik; Sagave, Julia Fritzi; Krobert, Kurt Allen; Edvardsen, Thor; Valen, Guro; Skomedal, Tor; Osnes, Jan-Bjørn & Attramadal, Håvard (2008). Connective tissue growth factor (CTGF/CCN2) desensitizes myocardial beta-adrenergic receptor signaling and inhibits isoproterenol induced hypertrophy.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Arnkværn, Kristin; Florholmen, Geir; Levy, Finn Olav; Tasken, Kjetil; Christensen, Geir Arve & Skjønsberg, Ole Henning (2008). Mechanisms for cardiac dysfunction in COPD and respiratory failure.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Florholmen, Geir; Arnkværn, Kristin; Levy, Finn Olav; Skjønsberg, Ole Henning; Tasken, Kjetil & Christensen, Geir Arve (2008). Alveolar hypoxia induces cardiac diastolic dysfunction: a role for a reduction in the calcium regulating protein phospholamban induced by IL-18.
  • Krobert, Kurt Allen; Hussain, Rizwan; Mørk, Halvor Kjeang; Qvigstad, Eirik; Sjaastad, Ivar; Osnes, Jan-Bjørn; Skomedal, Tor & Levy, Finn Olav (2007). cAMP-dependent inotropic effects are differentially regulated by muscarinic inhibition in failing rat ventricle. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  42(6), s S35- S35
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Florholmen, Geir; Arnkværn, Kristin; Levy, Finn Olav; Skjønsberg, Ole Henning; Tasken, Kjetil & Christensen, Geir Arve (2007). Alveolar hypoxia induces cardiac dysfunction, possibly mediated through increased amounts of phosphatases, leading to dephosphorylation of calcium regulatory proteins.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Florholmen, Geir; Arnkværn, Kristin; Levy, Finn Olav; Skjønsberg, Ole Henning; Tasken, Kjetil & Christensen, Geir Arve (2007). Diastolic dysfunction in alveolar hypoxia: A role for interleukin-18 induced increase in protein phosphatase 2A and reduction in phospholamban phosphorylation.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Florholmen, Geir; Arnkværn, Kristin; Levy, Finn Olav; Skjønsberg, Ole Henning; Tasken, Kjetil & Christensen, Geir Arve (2007). Hypoxia induced cardiac dysfunction maybe caused by increased IL-18 levels leading to dephosphorylation of Ca2+ handling proteins.
  • Larsen, Karl-Otto; Lygren, Birgitte; Sjaastad, Ivar; Krobert, Kurt Allen; Florholmen, Geir; Arnkværn, Kristin; Levy, Finn Olav; Skjønsberg, Ole Henning; Tasken, Kjetil & Christensen, Geir Arve (2007). Increased PP1 and PP2A mediating reduced Ser16 phosphorylated PLB is a possible mechanism for cardiac dysfunction in alveolar hypoxia. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  42(6), s S245- S245
  • Andressen, Kjetil Wessel; Norum, Jens Henrik; Levy, Finn Olav & Krobert, Kurt Allen (2006). Activation of adenylyl cyclase in HEK293 cells by endogenous G(s)-coupled receptors is attenuated by 5-HT7 receptor expression. Journal of Pharmacological Sciences (JPS).  ISSN 1347-8613.  101, s 128- 128
  • Birkeland, Jon Arne; Sjaastad, Ivar; Brattelid, Trond; Qvigstad, Eirik; Moberg, Enrica Ratti; Krobert, Kurt Allen; Bjørnerheim, Reidar; Skomedal, Tor; Sejersted, Ole M; Osnes, Jan-Bjørn & Levy, Finn Olav (2006). Treatment with a 5-HT4 serotonin receptor antagonist improves function of the failing heart. Journal of Pharmacological Sciences (JPS).  ISSN 1347-8613.  101, s 75- 75
  • Birkeland, Jon Arne; Sjaastad, Ivar; Brattelid, Trond; Qvigstad, Eirik; Moberg, Enrica Ratti; Krobert, Kurt Allen; Bjørnerheim, Reidar; Skomedal, Tor; Sejersted, Ole M; Osnes, Jan-Bjørn & Levy, Finn Olav (2006). Treatment with a 5-HT4 serotonin receptor antagonist improves function of the failing heart. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  40, s 943- 944
  • Brattelid, Trond; Qvigstad, Eirik; Birkeland, Jon Arne; Swift, Fredrik; Bekkevold, Silje Veslemøy; Krobert, Kurt Allen; Sejersted, Ole M; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav & Sjaastad, Ivar (2006). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Pharmacological Sciences (JPS).  ISSN 1347-8613.  101, s 74- 74
  • Brattelid, Trond; Qvigstad, Eirik; Birkeland, Jon Arne; Swift, Fredrik; Bekkevold, SVS; Krobert, Kurt Allen; Sejersted, Ole M; Skomedal, Tor; Osnes, Jan-Bjørn; Levy, Finn Olav & Sjaastad, Ivar (2006). Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  40, s 944- 945
  • Eikemo, Hilde; Qvigstad, Eirik; Krobert, Kurt Allen; Nunn, Caroline; Levy, Finn Olav; Skomedal, Tor & Osnes, Jan-Bjørn (2006). Kinetics of myosin light chain phosphorylation in the heart. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  40, s 994- 995
  • Qvigstad, Eirik; Sjaastad, Ivar; Brattelid, Trond; Nunn, Caroline; Swift, Fredrik; Birkeland, Jon Arne; Krobert, Kurt Allen; Andersen, Geir Øystein; Sejersted, Ole M; Osnes, Jan-Bjørn; Levy, Finn Olav & Skomedal, Tor (2006). Induction of functional serotonin 5-HT2A and 5-HT4 receptors in the acute failing cardiac ventricle. Journal of Pharmacological Sciences (JPS).  ISSN 1347-8613.  101, s 73- 73
  • Birkeland, Jon Arne; Qvigstad, Eirik; Sjaastad, Ivar; Brattelid, Trond; Krobert, Kurt Allen; Sejersted, Ole M; Ferrier, GR; Louch, W; Skomedal, Tor; Osnes, Jan-Bjørn & Levy, Finn Olav (2005). Induction of a 5-HT4 receptor-mediated inotropic response to serotonin in failing ventricular cardiomyocytes. Biophysical Journal.  ISSN 0006-3495.  88
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Publisert 13. apr. 2011 11:40 - Sist endret 27. mai 2011 15:55