Ted Reichborn-Kjennerud

• Heiberg, Ina Heidi; Nesvåg, Ragnar; Balteskard, Lise; Bramness, Jørgen Gustav; Hultman, Christina M.; Næss, Øyvind; Reichborn-Kjennerud, Ted; Ystrøm, Eivind; Jacobsen, Bjarne K. & Høye, Anne (2020). Diagnostic tests and treatment procedures performed prior to cardiovascular death in individuals with severe mental illness. Acta Psychiatrica Scandinavica.  ISSN 0001-690X.  141, s 439- 451 . doi: 10.1111/acps.13157 Fulltekst i vitenarkiv.
• Lund, Ingunn Olea; Eilertsen, Espen Moen; Gjerde, Line C.; Torvik, Fartein Ask; Røysamb, Espen; Reichborn-Kjennerud, Ted & Ystrøm, Eivind (2020). Maternal Drinking and Child Emotional and Behavior Problems. Pediatrics.  ISSN 0031-4005.  145(3) . doi: 10.1542/peds.2019-2007
• Villanger, Gro Dehli; Drover, Samantha S.M.; Nethery, Rachel C.; Thomsen, Cathrine; Sakhi, Amrit Kaur; Øvergaard, Kristin Romvig; Zeiner, Pål; Hoppin, Jane A.; Reichborn-Kjennerud, Ted; Aase, Heidi & Engel, Stephanie M. (2020). Associations between urine phthalate metabolites and thyroid function in pregnant women and the influence of iodine status. Environment International.  ISSN 0160-4120.  137 . doi: 10.1016/j.envint.2020.105509 Fulltekst i vitenarkiv.
• Villanger, Gro Dehli; Ystrøm, Eivind; Engel, Stephanie M.; Longnecker, Matthew P.; Pettersen, Rolf Dagfinn; Rowe, Alexander D.; Reichborn-Kjennerud, Ted & Aase, Heidi (2020). Neonatal thyroid‐stimulating hormone and association with attention‐deficit/hyperactivity disorder. Paediatric and Perinatal Epidemiology.  ISSN 0269-5022. . doi: 10.1111/ppe.12643
• Ask, Helga; Handal, Marte; Hauge, Lars Johan; Reichborn-Kjennerud, Ted & Skurtveit, Svetlana (2019). Incidence of diagnosed pediatric anxiety disorders and use of prescription drugs: a nation‑wide registry study. European Child and Adolescent Psychiatry.  ISSN 1018-8827. . doi: 10.1007/s00787-019-01419-0
• Biele, Guido; Gustavson, Kristin; Czajkowski, Nikolai Olavi; Nilsen, Roy Miodini; Reichborn-Kjennerud, Ted; Magnus, Per; Stoltenberg, Camilla & Aase, Heidi (2019). Bias from self selection and loss to follow-up in prospective cohort studies. European Journal of Epidemiology (EJE).  ISSN 0393-2990.  34(10), s 927- 938 . doi: 10.1007/s10654-019-00550-1
• Gjerde, Line C.; Eilertsen, Espen Moen; Hannigan, Laurie; Eley, Thalia C.; Røysamb, Espen; Reichborn-Kjennerud, Ted; Rijsdijk, Frühling V.; McAdams, Tom A. & Ystrøm, Eivind (2019). Associations between maternal depressive symptoms and risk for offspring early-life psychopathology: the role of genetic and non-genetic mechanisms. Psychological Medicine.  ISSN 0033-2917. . doi: 10.1017/s0033291719003301 Fulltekst i vitenarkiv.
• Gudmundsson, Ólafur Ó.; Walters, Gudmundur Bragi; Ingason, Andrés; Johansson, Stefan; Zayats, Tetyana; Athanasiu, Lavinia; Sønderby, Ida Elken; Gustafsson, Omar; Nawaz, Muhammad Sulaman; Jónsson, Gudbjörn F.; Jónsson, Lina; Knappskog, Per; Ingvarsdóttir, Ester; Davidsdóttir, Katrin; Djurovic, Srdjan; Knudsen, Gun Peggy Strømstad; Askeland, Ragna Bugge; Haraldsdóttir, Gyda S.; Baldursson, Gísli; Magnússon, Páll; Sigurdsson, Engilbert; Gudbjartsson, Daníel Fannar; Stéfansson, Hreinn; Andreassen, Ole Andreas; Haavik, Jan; Reichborn-Kjennerud, Ted & Stefánsson, Kári (2019). Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder. Translational psychiatry.  ISSN 2158-3188.  9, s 1- 9 . doi: 10.1038/s41398-019-0599-y Fulltekst i vitenarkiv.
• Gustavson, Kristin; Ask, Helga; Ystrøm, Eivind; Stoltenberg, Camilla; Lipkin, W. Ian; Suren, Pål; Håberg, Siri Eldevik; Magnus, Per; Knudsen, Gun Peggy S.; Eilertsen, Espen Moen; Bresnahan, Michaeline; Aase, Heidi; Mjaaland, Siri; Susser, Ezra S.; Hornig, Mady & Reichborn-Kjennerud, Ted (2019). Maternal fever during pregnancy and offspring attention deficit hyperactivity disorder. Scientific Reports.  ISSN 2045-2322.  9:9519, s 1- 10 . doi: 10.1038/s41598-019-45920-7 Fulltekst i vitenarkiv.
• Heiberg, Ina Heidi; Jacobsen, Bjarne K.; Balteskard, Lise; Bramness, Jørgen Gustav; Næss, Øyvind; Ystrøm, Eivind; Reichborn-Kjennerud, Ted; Hultman, Christina M.; Nesvåg, Ragnar & Høye, Anne (2019). Undiagnosed cardiovascular disease prior to cardiovascular death in individuals with severe mental illness. Acta Psychiatrica Scandinavica.  ISSN 0001-690X.  139(6), s 558- 571 . doi: 10.1111/acps.13017 Fulltekst i vitenarkiv.
• Hysing, Mari; Reichborn-Kjennerud, Ted; Markestad, Trond; Elgen, Irene Bircow & Sivertsen, Børge (2019). Sleep Duration and Nocturnal Awakenings in Infants Born with Gestational Risk. Journal of Developmental and Behavioral Pediatrics.  ISSN 0196-206X.  40(3), s 192- 199 . doi: 10.1097/DBP.0000000000000642 Fulltekst i vitenarkiv.
• Kendler, Kenneth S.; Aggen, Steven H.; Gillespie, Nathan; Czajkowski, Nikolai Olavi; Ystrøm, Eivind & Reichborn-Kjennerud, Ted (2019). A twin study of cigarette and snus initiation and quantity of use in Norwegian Adult Twins. Twin Research and Human Genetics.  ISSN 1832-4274.  22(2), s 108- 113 . doi: 10.1017/thg.2019.9 Fulltekst i vitenarkiv.
• Kendler, Kenneth S.; Aggen, Steven H.; Gillespie, Nathan; Krueger, Robert F.; Czajkowski, Nikolai Olavi; Ystrøm, Eivind & Reichborn-Kjennerud, Ted (2019). The structure of genetic and environmental influences on normative personality, abnormal personality traits, and personality disorder symptoms. Psychological Medicine.  ISSN 0033-2917.  49(8), s 1392- 1399 . doi: 10.1017/S0033291719000047
• Lee, Phil H.; Antilla, Verneri; Won, Hyejung; Feng, Yen-Chen A.; Rosenthal, Jacob; Zhu, Zhaozhong; Tucker-Drob, Elliot M.; Nivard, Michel G.; Grotzinger, Andrew D.; Posthuma, Danielle; Yu, Dongmei; Stahl, Eli A.; Walters, Raymond K.; Anney, Richard J.L.; Duncan, Laramie E.; Ge, Tian; Belangero, Sintia I.; Cook, Edwin H.; Hoekstra, Pieter J.; Keski-Rahkonen, Anna; Kirov, George; Luykx, Jurjen J.; Rohde, Luis A.; Agerbo, Esben; Arranz, M.J.; Asherson, Philip; Bækvad-Hansen, Marie; Bellgrove, Mark A.; Belliveau Jr, Richard A.; Buitelaar, Jan; Bybjerg-Grauholm, Jonas; Casas, Miquel; Chambert, Kimberly; Cerrato, Felecia; Churchhouse, Claire; Cormand, Bru; Crosbie, Jennifer; Dalsgaard, Søren; Haavik, Jan; Hakonarson, Hakon; Hansen, Christine S.; Mors, Ole; Zayats, Tetyana; Bettella, Francesco; Hope, Sigrun; Hultman, Christina M.; Nærland, Terje; Bøen, Erlend; Elvsåshagen, Torbjørn; Ødegaard, Ketil Joachim; Malt, Ulrik Fredrik; Melle, Ingrid; Reinbold, Céline Sonja; Smeland, Olav Bjerkehagen; Wang, Yunpeng; Espeseth, Thomas; Knudsen, Gun Peggy Strømstad; Le Hellard, Stephanie; Reichborn-Kjennerud, Ted; Jönsson, Erik Gunnar; Andreassen, Ole Andreas; Agartz, Ingrid; Morken, Gunnar; Stordal, Eystein; Vaaler, Arne & Joa, Inge (2019). Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders. Cell.  ISSN 0092-8674.  179(7), s 1469- 1482 . doi: 10.1016/j.cell.2019.11.020 Fulltekst i vitenarkiv.
• Leppert, Beate; Havdahl, Alexandra; Riglin, Lucy; Jones, Hannah J.; Zheng, Jie; Davey Smith, George; Tilling, Kate; Thapar, Anita; Reichborn-Kjennerud, Ted & Stergiakouli, Evie (2019). Association of maternal neurodevelopmental risk alleles with early-life exposures. JAMA psychiatry.  ISSN 2168-6238.  76(8), s 834- 842 . doi: 10.1001/jamapsychiatry.2019.0774 Fulltekst i vitenarkiv.
• Lund, Ingunn Olea; Eilertsen, Espen Moen; Gjerde, Line C.; Røysamb, Espen; Wood, Mollie; Reichborn-Kjennerud, Ted & Ystrøm, Eivind (2019). Is the association between maternal alcohol consumption in pregnancy and pre-school child behavioural and emotional problems causal? Multiple approaches for controlling unmeasured confounding. Addiction.  ISSN 0965-2140.  114(6), s 1004- 1014 . doi: 10.1111/add.14573 Fulltekst i vitenarkiv.
• O`Connell, Kevin; Shadrin, Alexey A.; Bahrami, Shahram; Smeland, Olav Bjerkehagen; Bettella, Francesco; Frei, Oleksandr; Krull, Florian; Askeland, Ragna Bugge; Walters, Bragi; Davíðsdóttir, Katrín; Haraldsdóttir, Gyða; Guðmundsson, Ólafur; Stefánsson, Hreinn; Fan, Chun C.; Steen, Nils Eiel; Reichborn-Kjennerud, Ted; Dale, Anders M.; Stefánsson, Kári; Djurovic, Srdjan & Andreassen, Ole Andreas (2019). Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder. Molecular Psychiatry.  ISSN 1359-4184.  s 1- 11 . doi: 10.1038/s41380-019-0613-z Fulltekst i vitenarkiv. Vis sammendrag

  Differential diagnosis between childhood onset attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) remains a challenge, mainly due to overlapping symptoms and high rates of comorbidity. Despite this, genetic correlation reported for these disorders is low and non-significant. Here we aimed to better characterize the genetic architecture of these disorders utilizing recent large genome-wide association studies (GWAS). We analyzed independent GWAS summary statistics for ADHD (19,099 cases and 34,194 controls) and BD (20,352 cases and 31,358 controls) applying the conditional/conjunctional false discovery rate (condFDR/conjFDR) statistical framework that increases the power to detect novel phenotype-specific and shared loci by leveraging the combined power of two GWAS. We observed cross-trait polygenic enrichment for ADHD conditioned on associations with BD, and vice versa. Leveraging this enrichment, we identified 19 novel ADHD risk loci and 40 novel BD risk loci at condFDR <0.05. Further, we identified five loci jointly associated with ADHD and BD (conjFDR < 0.05). Interestingly, these five loci show concordant directions of effect for ADHD and BD. These results highlight a shared underlying genetic risk for ADHD and BD which may help to explain the high comorbidity rates and difficulties in differentiating between ADHD and BD in the clinic. Improving our understanding of the underlying genetic architecture of these disorders may aid in the development of novel stratification tools to help reduce these diagnostic difficulties.

• O`Connell, Kevin; Shadrin, Alexey A.; Smeland, Olav Bjerkehagen; Bahrami, Shahram; Frei, Oleksandr; Bettella, Francesco; Krull, Florian; Fan, Chun C.; Askeland, Ragna Bugge; Knudsen, Gun Peggy Strømstad; Halmøy, Anne; Steen, Nils Eiel; Ueland, Torill; Walters, G. Bragi; Davíðsdóttir, Katrín; Haraldsdóttir, Gyda S.; Guðmundsson, Ólafur; Stefansson, Hreinn; Reichborn-Kjennerud, Ted; Haavik, Jan; Dale, Anders M.; Stefánsson, Kári; Djurovic, Srdjan & Andreassen, Ole Andreas (2019). Identification of genetic loci shared between ADHD, intelligence and educational attainment. Biological Psychiatry.  ISSN 0006-3223. . doi: 10.1016/j.biopsych.2019.11.015 Fulltekst i vitenarkiv.
• Reichborn-Kjennerud, Ted & Telle, Kjetil Elias (2019). Likeverdig behandling av psykisk sykdom. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  139(13) . doi: 10.4045/tidsskr.19.0545
• Rosenström, Tom Henrik; Czajkowski, Nikolai Olavi; Ystrøm, Eivind; Krueger, Robert F; Aggen, Steven H; Gillespie, Nathan A; Eilertsen, Espen Moen; Reichborn-Kjennerud, Ted & Torvik, Fartein Ask (2019). Genetically Informative Mediation Modeling Applied to Stressors and Personality-Disorder Traits in Etiology of Alcohol Use Disorder. Behavior Genetics.  ISSN 0001-8244.  49(1), s 11- 23 . doi: 10.1007/s10519-018-9941-z
• Seglem, Karoline Brobakke; Torvik, Fartein Ask; Røysamb, Espen; Gjerde, Line C.; Magnus, Per; Reichborn-Kjennerud, Ted; Svedberg, Pia & Ørstavik, Ragnhild (2019). A Life Course Study of Genetic and Environmental Influences on Work Incapacity. Twin Research and Human Genetics.  ISSN 1832-4274.  s 1- 7 . doi: 10.1017/thg.2019.116 Fulltekst i vitenarkiv.
• Suren, Pål; Bakken, Inger Johanne Landsjøåsen; Skurtveit, Svetlana; Handal, Marte; Reichborn-Kjennerud, Ted; Stoltenberg, Camilla; Nøstvik, Liv Irene & Weidle, Bernhard (2019). Tourettes syndrom hos barn i Norge. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  139(17), s 1648- 1653 . doi: 10.4045/tidsskr.19.0411 Fulltekst i vitenarkiv.
• Suren, Pål; Havdahl, Alexandra; Bresnahan, Michaeline; Hirtz, Deborah; Hornig, Mady; Lord, Catherine; Reichborn-Kjennerud, Ted; Schjølberg, Synnve; Øyen, Anne-Siri; Magnus, Per; Susser, Ezra; Lipkin, W. Ian & Stoltenberg, Camilla (2019). Sensitivity and specificity of early screening for autism. BJPsych Open.  ISSN 2056-4724.  5(3) . doi: 10.1192/bjo.2019.34 Fulltekst i vitenarkiv.
• Suren, Pål; Havdahl, Alexandra; Øyen, Anne-Siri; Schjølberg, Synnve; Reichborn-Kjennerud, Ted; Magnus, Per; Bakken, Inger Johanne Landsjøåsen & Stoltenberg, Camilla (2019). Diagnostisering av autismespekterforstyrrelser hos barn i Norge. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  139(14), s 1372- 1379 . doi: 10.4045/tidsskr.18.0960 Fulltekst i vitenarkiv. Vis sammendrag

  BACKGROUND:The percentage share of children who are diagnosed with autism spectrum disorder has increased considerably since the 1990s in Norway as well as in other countries. It has previously been demonstrated that there is considerable variation between counties with respect to diagnostic practice. MATERIAL AND METHOD:We calculated the percentage of children with autism spectrum disorder by using patient data obtained from the Norwegian Patient Registry and population data obtained from the National Registry. The calculations were made for the country as a whole as well as by county. The diagnostic assessments and documentation were mapped by linking the Norwegian Patient Registry with the Norwegian Mother, Father and Child Cohort study. We also reviewed patient records obtained from the specialist health service and considered whether diagnostic practice satisfied the research criteria for autism spectrum disorder. RESULTS:By the age of eight, 1.1 % of boys and 0.3 % of girls had been diagnosed with autism spectrum disorder. The overall percentages varied from 0.3 to 1.0 between counties. From 2008 to 2016, these percentages increased in all age groups. Our review of patient records included 503 children. In 95 % of cases the patient records provided a high standard of documentation that the diagnostic research criteria had been satisfied. The assessments were largely conducted in accordance with the guidelines drawn up by the various health trusts. INTERPRETATION:Autism diagnoses are generally well documented within the Norwegian specialist health service and meet the diagnostic criteria. In the counties that demonstrate a low prevalence of autism, it appears the health service fails to recognise autism in many children, particularly girls, or the diagnosis is determined late.

• Torvik, Fartein Ask; Rosenström, Tom Henrik; Gustavson, Kristin; Ystrøm, Eivind; Kendler, Kenneth S.; Bramness, Jørgen Gustav; Czajkowski, Nikolai Olavi & Reichborn-Kjennerud, Ted (2019). Explaining the association between anxiety disorders and alcohol use disorder: A twin study. Depression and Anxiety.  ISSN 1091-4269.  36(6), s 522- 532 . doi: 10.1002/da.22886 Fulltekst i vitenarkiv.
• Watson, Hunna J.; Yilmaz, Zeynep; Thornton, Laura M.; Hübel, Christopher; Coleman, Jonathan R. I.; Gaspar, Héléna A.; Bryois, Julien; Hinney, Anke; Leppä, Virpi M.; Mattheisen, Manuel; Medland, Sarah E.; Ripke, Stephan; Yao, Shuyang; Giusti-Rodríguez, Paola; Hanscombe, Ken B.; Purves, Kirstin L.; Adan, Roger A.H.; Alfredsson, Lars; Ando, Tetsuya; Andreassen, Ole Andreas; Baker, Jessica H; Berrettini, Wade H.; Boehm, Ilka; Boni, Claudette; Perica, Vesna Boraska; Buehren, Katharina; Burghardt, Roland; Cassina, Matteo; Cichon, Sven; Clementi, Maurizio; Cone, Roger D.; Courtet, Philippe; Crow, Scott; Crowley, James J.; Danner, Unna N.; Davis, Oliver S.P.; de Zwaan, Martina; Dedoussis, George; Degortes, Daniela; DeSocio, Janiece E.; Dick, Danielle M.; Dikeos, Dimitris; Dina, Christian; Dmitrzak-Weglarz, Monika; Docampo, Elisa; Duncan, Laramie E.; Egberts, Karin; Ehrlich, Stefan; Escaramis, Geòrgia; Esko, Tõnu; Estivill, Xavier; Farmer, Anne; Favaro, Angela; Fernández-Aranda, Fernando; Fichter, Manfred M.; Fischer, Krista; Föcker, Manuel; Foretova, Lenka; Forstner, Andreas J.; Forzan, Monica; Franklin, Christopher S.; Gallinger, Steven; Giegling, Ina; Giuranna, Johanna; Gonidakis, Fragiskos; Gorwood, Philip; Mayora, Monica Gratacos; Guillaume, Sebastien; Guo, Yiran; Hakonarson, Hakon; Hatzikotoulas, Konstantinos; Hauser, Joanna; Hebebrand, Johannes; Helder, Sietske G.; Herms, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Huckins, Laura M.; Hudson, James I.; Imgart, Hartmut; Inoko, Hidetoshi; Janout, Vladimir; Jiménez-Murcia, Susana; Julià, Antonio; Kalsi, Gursharan; Kaminská, Deborah; Kaprio, Jaakko; Karhunen, Leila; Karwautz, Andreas; Kas, Martien J.H.; Kennedy, James L.; Keski-Rahkonen, Anna; Kiezebrink, Kirsty; Kim, Youl-Ri; Klareskog, Lars; Klump, Kelly L.; Knudsen, Gun Peggy S.; La Via, Maria C.; Le Hellard, Stephanie; Levitan, Robert D.; Li, Dong; Lilenfeld, Lisa; Lin, Bochao Danae; Lissowska, Jolanta; Luykx, Jurjen; Magistretti, Pierre J.; Maj, Mario; Mannik, Katrin; Marsal, Sara; Marshall, Christian R.; Mattingsdal, Morten; McDevitt, Sara; McGuffin, Peter; Metspalu, Andres; Meulenbelt, Ingrid; Micali, Nadia; Mitchell, Karen; Monteleone, Alessio Maria; Monteleone, Palmiero; Munn-Chernoff, Melissa A.; Nacmias, Benedetta; Navratilova, Marie; Ntalla, Ioanna; O'Toole, Julie K.; Ophoff, Roel A.; Padyukov, Leonid; Palotie, Aarno; Pantel, Jacques; Papezova, Hana; Pinto, Dalila; Rabionet, Raquel; Raevuori, Anu; Ramoz, Nicolas; Reichborn-Kjennerud, Ted; Ricca, Valdo; Ripatti, Samuli; Ritschel, Franziska; Roberts, Marion; Rotondo, Alessandro; Rujescu, Dan; Rybakowski, Filip; Santonastaso, Paolo; Scherag, André; Scherer, Stephen W.; Schmidt, Ulrike; Schork, Nicholas J.; Schosser, Alexandra; Seitz, Jochen; Slachtova, Lenka; Slagboom, P. Eline; Slof-Op `t Landt, Margarita C.T.; Slopien, Agnieszka; Sorbi, Sandro; Świątkowska, Beata; Szatkiewicz, Jin P.; Tachmazidou, Ioanna; Tenconi, Elena; Tortorella, Alfonso; Tozzi, Federica; Treasure, Janet; Tsitsika, Artemis; Tyszkiewicz-Nwafor, Marta; Tziouvas, Konstantinos; van Elburg, Annemarie A.; van Furth, Eric F.; Wagner, Gudrun; Walton, Esther; Widen, Elisabeth; Zeggini, Eleftheria; Zerwas, Stephanie; Zipfel, Stephan; Bergen, Andrew W.; Boden, Joseph M.; Brandt, Harry; Crawford, Steven; Halmi, Katherine A.; Horwood, L. John; Johnson, Craig; Kaplan, Allan S.; Kaye, Walter H.; Mitchell, James E.; Olsen, Catherine M.; Pearson, John F.; Pedersen, Nancy L.; Strober, Michael; Werge, Thomas; Whiteman, David C.; Woodside, D. Blake; Stuber, Garret D.; Gordon, Scott; Grove, Jakob; Henders, Anjali K.; Juréus, Anders; Kirk, Katherine M.; Larsen, Janne T.; Parker, Richard; Petersen, Liselotte; Jordan, Jennifer; Kennedy, Martin; Montgomery, Grant W.; Wade, Tracey D.; Birgegård, Andreas; Lichtenstein, Paul; Norring, Claes; Landén, Mikael; Martin, Nicholas G.; Mortensen, Preben Bo; Sullivan, Patrick F.; Breen, Gerome & Bulik, Cynthia M. (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics.  ISSN 1061-4036.  51(8), s 1207- 1214 . doi: 10.1038/s41588-019-0439-2
• Watson, Hunna J; Diemer, Elizabeth W; Zerwas, Stephanie; Gustavson, Kristin; Knudsen, Gun Peggy S.; Torgersen, Leila; Reichborn-Kjennerud, Ted & Bulik, Cynthia M (2019). Prenatal and perinatal risk factors for eating disorders in women: A population cohort study. International Journal of Eating Disorders.  ISSN 0276-3478.  52(6), s 643- 651 . doi: 10.1002/eat.23073
• Ørbeck, Beate; Øvergaard, Kristin Romvig; Pripp, Are Hugo; Aase, Heidi; Reichborn-Kjennerud, Ted & Zeiner, Pål (2019). Adult ADHD Symptoms and Satisfaction With Life: Does Age and Sex Matter?. Journal of Attention Disorders.  ISSN 1087-0547.  23(1), s 3- 11 . doi: 10.1177/1087054715612257 Fulltekst i vitenarkiv. Vis sammendrag

  Objective:To investigate adult ADHD symptoms and satisfaction with life, with a focus on age and sex differences. Method: This study is based on parents in the Norwegian Mother and Child Cohort Study (MoBa). The Adult Self- Report Scale (ASRS-6) and Satisfaction With Life Scale (SWLS) scores were analyzed from 33,210 men and 41,983 women from young to middle adulthood. Results: Mean ASRS total score was significantly higher in men, where 5.1% scored above cutoff, compared with 2.9% in women. Factor loadings supported the two ASRS subscales: Inattention (Inatt) and Hyperactivity-Impulsivity (HyImp) in both sexes. A significant decline with age was found on HyImp, whereas Inatt scores were reasonably stable in men and u-curved in women. High ASRS scores were associated with lower SWLS, but poor satisfaction with life was found only in high-scoring women. Conclusion: Our findings suggest caution to age and sex when using the ASRS-6.

• Anttila, Verneri; Bulik-Sullivan, Brendan; Finucane, Hilary K.; Walters, Raymond K.; Bras, Jose; Duncan, Laramie; Escott-Price, Valentina; Falcone, Guido; Gormley, Padhraig; Malik, Rainer; Patsopoulos, Nikolaos A.; Ripke, Stephan; Wei, Zhi; Yu, Dongmei; Lee, Phil H.; Turley, Patrick; Grenier-Boley, Benjamin; Chouraki, Vincent; Kamatani, Yoichiro; Berr, Claudine; Letenneur, Luc; Hannequin, Didler; Amouyel, Philippe; Boland, Anne; Deleuze, Jean-François; Duron, Emmanuelle; Vardarajan, Badri N.; Reitz, Christiane; Goate, Alison M.; Huentelman, Matthew; Kamboh, M. Ilyas; Larson, Eric B.; Rogaeva, Ekaterina; St George-Hyslop, Peter; Hakonarson, Hakon; Kukull, Walter A.; Farrer, Lindsay A.; Barnes, Lisa L.; Beach, Thomas G.; Demirci, F. 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Science.  ISSN 0036-8075.  360(6395) . doi: 10.1126/science.aap8757
• Ask, Helga; Gustavson, Kristin; Ystrøm, Eivind; Havdahl, Karoline Alexandra; Tesli, Martin Steen; Askeland, Ragna Bugge & Reichborn-Kjennerud, Ted (2018). Association of Gestational Age at Birth With Symptoms of Attention-Deficit/Hyperactivity Disorder in Children. JAMA pediatrics.  ISSN 2168-6203.  172(8), s 749- 756 . doi: 10.1001/jamapediatrics.2018.1315
• Czajkowski, Nikolai Olavi; Aggen, Steven H.; Krueger, Robert F; Kendler, Kenneth S.; Neale, Michael C.; Knudsen, Gun Peggy; Gillespie, Nathan A.; Røysamb, Espen; Tambs, Kristian & Reichborn-Kjennerud, Ted (2018). A Twin Study of Normative Personality and DSM-IV Personality Disorder Criterion Counts: Evidence for Separate Genetic Influences. American Journal of Psychiatry.  ISSN 0002-953X.  175(7), s 649- 656 . doi: 10.1176/appi.ajp.2017.17050493
• Dieset, Ingrid; Mørch, Ragni Helene; Hope, Sigrun; Hoseth, Eva Zsuzsanna; Reponen, Elina Johanna; Gran, Jon Michael; Aas, Monica; Michelsen, Annika; Reichborn-Kjennerud, Ted; Nesvåg, Ragnar; Agartz, Ingrid; Melle, Ingrid; Aukrust, Pål; Djurovic, Srdjan; Ueland, Torill & Andreassen, Ole Andreas (2018). An association between YKL-40 and type 2 diabetes in psychotic disorders. Acta Psychiatrica Scandinavica.  ISSN 0001-690X.  139, s 37- 45 . doi: 10.1111/acps.12971
• Drover, Samantha S.M.; Villanger, Gro Dehli; Aase, Heidi; Skogheim, Thea Steen; Longnecker, Matthew P.; Zoeller, R. Thomas; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy S.; Zeiner, Pål & Engel, Stephanie M. (2018). Maternal thyroid function during pregnancy or neonatal thyroid function and attention deficit hyperactivity disorder: A systematic review. Epidemiology.  ISSN 1044-3983.  30(1), s 130- 144 . doi: 10.1097/EDE.0000000000000937
• Eilertsen, Espen Moen; Gjerde, Line C.; Kendler, Kenneth S.; Røysamb, Espen; Aggen, Steven H.; Gustavson, Kristin; Reichborn-Kjennerud, Ted & Ystrøm, Eivind (2018). Development of ADHD symptoms in preschool children: Genetic and environmental contributions. Development and Psychopathology.  ISSN 0954-5794.  31(4), s 1299- 1305 . doi: 10.1017/S0954579418000731 Fulltekst i vitenarkiv.
• Engel, Stephanie M.; Villanger, Gro Dehli; Nethery, Rachel C.; Thomsen, Cathrine; Sakhi, Amrit Kaur; Drover, Samantha S.M.; Hoppin, Jane A.; Zeiner, Pål; Knudsen, Gun Peggy S.; Reichborn-Kjennerud, Ted; Herring, Amy H. & Aase, Heidi (2018). Prenatal Phthalates, Maternal Thyroid Function, and Risk of Attention-Deficit Hyperactivity Disorder in the Norwegian Mother and Child Cohort. Environmental Health Perspectives.  ISSN 0091-6765.  126(5) . doi: 10.1289/EHP2358 Fulltekst i vitenarkiv.
• Gillespie, Nathan A.; Aggen, Steven H.; Gentry, Amanda E.; Neale, Michael Churton; Knudsen, Gun Peggy S.; Krueger, Robert Frederick; South, Susan Carol; Czajkowski, Nikolai Olavi; Nesvåg, Ragnar; Ystrøm, Eivind; Rosenström, Tom Henrik; Torvik, Fartein Ask; Reichborn-Kjennerud, Ted & Kendler, Kenneth Seedman (2018). Testing Genetic and Environmental Associations Between Personality Disorders and Cocaine Use: A Population-Based Twin Study. Twin Research and Human Genetics.  ISSN 1832-4274.  21(1), s 24- 32 . doi: 10.1017/thg.2017.73 Fulltekst i vitenarkiv.
• Gillespie, Nathan A.; Aggen, Steven H.; Neale, Michael C.; Knudsen, Gun Peggy S.; Krueger, Robert F.; South, Susan C.; Czajkowski, Nikolai Olavi; Nesvåg, Ragnar; Ystrøm, Eivind; Kendler, Kenneth S. & Reichborn-Kjennerud, Ted (2018). Associations between personality disorders and cannabis use and cannabis use disorder: a population‐based twin study. Addiction.  ISSN 0965-2140.  113(8), s 1488- 1498 . doi: 10.1111/add.14209
• Gjerde, Line C.; Eilertsen, Espen Moen; Eley, Thalia C.; McAdams, Tom A.; Reichborn-Kjennerud, Ted; Røysamb, Espen & Ystrøm, Eivind (2018). Maternal Perinatal and Concurrent Anxiety and Mental Health Problems in Early Childhood: A Sibling‐Comparison Study. Child Development.  ISSN 0009-3920. . doi: 10.1111/cdev.13192 Fulltekst i vitenarkiv.
• Gustavson, Kristin; Knudsen, Ann Kristin; Nesvåg, Ragnar; Knudsen, Gun Peggy S.; Vollset, Stein Emil & Reichborn-Kjennerud, Ted (2018). Prevalence and stability of mental disorders among young adults: Findings from a longitudinal study. BMC Psychiatry.  ISSN 1471-244X.  18 . doi: 10.1186/s12888-018-1647-5 Fulltekst i vitenarkiv.
• Hannigan, Laurie J; Eilertsen, Espen Moen; Gjerde, Line C.; Reichborn-Kjennerud, Ted; Eley, Thalia C; Rijsdijk, Frühling V.; Ystrøm, Eivind & McAdams, Tom A (2018). Maternal prenatal depressive symptoms and risk for early-life psychopathology in offspring: genetic analyses in the Norwegian Mother and Child Birth Cohort Study. Lancet psychiatry.  ISSN 2215-0374.  5(10), s 808- 815 . doi: 10.1016/S2215-0366(18)30225-6 Fulltekst i vitenarkiv.
• Heiberg, Ina Heidi; Jacobsen, Bjarne K.; Nesvåg, Ragnar; Bramness, Jørgen Gustav; Reichborn-Kjennerud, Ted; Næss, Øyvind; Ystrøm, Eivind; Hultman, Christina M. & Høye, Anne (2018). Total and cause-specific standardized mortality ratios in patients with schizophrenia and/or substance use disorder. PLOS ONE.  ISSN 1932-6203.  13(8) . doi: 10.1371/journal.pone.0202028 Fulltekst i vitenarkiv.
• Huckins, L M; Hatzikotoulas, K; Southam, L; Thornton, L M; Steinberg, J; Aguilera-McKay, F; Treasure, J; Schmidt, U; Gunasinghe, C; Romero, A; Curtis, C; Rhodes, D; Moens, J; Kalsi, G; Dempster, D; Leung, R; Keohane, A; Burghardt, R; Ehrlich, S; Hebebrand, J; Hinney, A; Ludolph, A; Walton, E; Deloukas, P; Hofman, A; Palotie, A; Palta, P; van Rooij, F J A; Stirrups, K; Adan, R; Boni, C; Cone, R; Dedoussis, G; van Furth, E; Gonidakis, F; Gorwood, P; Hudson, J; Kaprio, J; Kas, M; Keski-Rahonen, A; Kiezebrink, K; Knudsen, Gun Peggy; Slof-Op ’t Landt, M C T; Maj, M; Monteleone, A; Monteleone, P; Raevuori, A; Reichborn-Kjennerud, Ted; Tozzi, F; Tsitsika, A; Van Elburg, A; Collier, D A; Sullivan, P F; Breen, G; Bulik, C M & Zeggini, E (2018). Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Molecular Psychiatry.  ISSN 1359-4184.  23(5), s 1169- 1180 . doi: 10.1038/mp.2017.88 Fulltekst i vitenarkiv.
• Rosenqvist, Mina A.; Sjölander, Arvid; Ystrøm, Eivind; Larsson, Henrik & Reichborn-Kjennerud, Ted (2018). Adverse family life events during pregnancy and ADHD symptoms in five-year-old offspring. Journal of Child Psychology and Psychiatry and Allied Disciplines.  ISSN 0021-9630. . doi: 10.1111/jcpp.12990 Fulltekst i vitenarkiv.
• Rosenström, Tom Henrik; Gjerde, Line C.; Krueger, Robert Frederick; Aggen, Steven H.; Czajkowski, Nikolai Olavi; Gillespie, Nathan A.; Kendler, Kenneth S.; Reichborn-Kjennerud, Ted; Torvik, Fartein Ask & Ystrøm, Eivind (2018). Joint factorial structure of psychopathology and personality. Psychological Medicine.  ISSN 0033-2917. . doi: 10.1017/S0033291718002982 Fulltekst i vitenarkiv.
• Rosenström, Tom Henrik; Torvik, Fartein Ask; Ystrøm, Eivind; Czajkowski, Nikolai Olavi; Gillespie, Nathan A.; Aggen, Steven H.; Krueger, Robert F; Kendler, Kenneth S. & Reichborn-Kjennerud, Ted (2018). Prediction of alcohol use disorder using personality disorder traits: a twin study. Addiction.  ISSN 0965-2140.  113(1), s 15- 24 . doi: 10.1111/add.13951
• Suren, Pål; Thorstensen, Anne Gjertrud; Tørstad, Marit; Emhjellen, Petter Espeseth; Furu, Kari; Biele, Guido; Aase, Heidi; Stoltenberg, Camilla; Zeiner, Pål; Bakken, Inger Johanne & Reichborn-Kjennerud, Ted (2018). Diagnostikk av hyperkinetisk forstyrrelse hos barn i Norge. Tidsskrift for Den norske legeforening.  ISSN 0029-2001. . doi: 10.4045/tidsskr.18.0418 Fulltekst i vitenarkiv.
• Torvik, Fartein Ask; Gustavson, Kristin; Ystrøm, Eivind; Rosenström, Tom Henrik; Gillespie, Nathan; Reichborn-Kjennerud, Ted & Kendler, Kenneth S (2018). Continuity of genetic and environmental influences on clinically assessed major depression from ages 18 to 45. Psychological Medicine.  ISSN 0033-2917.  s 1- 9 . doi: 10.1017/S0033291718003550 Fulltekst i vitenarkiv.
• Torvik, Fartein Ask; Ystrøm, Eivind; Gustavson, Kristin; Rosenström, Tom Henrik; Bramness, Jørgen Gustav; Gillespie, N; Aggen, S H; Kendler, K S & Reichborn-Kjennerud, Ted (2018). Diagnostic and genetic overlap of three common mental disorders in structured interviews and health registries. Acta Psychiatrica Scandinavica.  ISSN 0001-690X.  137(1), s 54- 64 . doi: 10.1111/acps.12829 Fulltekst i vitenarkiv.
• Welander-Vatn, Audun; Torvik, Fartein Ask; Czajkowski, Nikolai Olavi; Kendler, Kenneth S; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy S. & Ystrøm, Eivind (2018). Relationships Among Avoidant Personality Disorder, Social Anxiety Disorder, and Normative Personality Traits: A Twin Study. Journal of Personality Disorders.  ISSN 0885-579X.  33(3), s 289- 309 . doi: 10.1521/pedi_2018_32_341
• Øvergaard, Kristin Romvig; Ørbeck, Beate; Aase, Heidi; Torgersen, Svenn; Reichborn-Kjennerud, Ted & Zeiner, Pål (2018). Emotional Lability in Preschoolers With Symptoms of ADHD. Journal of Attention Disorders.  ISSN 1087-0547.  22(8), s 787- 795 . doi: 10.1177/1087054715576342 Vis sammendrag

  OBJECTIVE: The aim of this study was to examine occurrence of emotional lability (EL) in preschoolers with ADHD symptoms versus controls. METHOD: The study was part of the Norwegian Mother and Child Cohort Study (MoBa) at the Norwegian Institute of Public Health. In the present study, 495 preschoolers were clinically examined. Symptoms of ADHD, anxiety, and oppositional defiant disorder (ODD) were measured with the Preschool Age Psychiatric Assessment Interview. An EL measure was obtained from the Emotional Control subscale of the Behavior Rating Inventory of Executive Function-Preschool Version (BRIEF-P), which parents and teachers completed. RESULTS: EL was significantly more frequent in the ADHD group compared with controls (25% vs. 7%, p < .001). By parent report, EL correlated significantly with ADHD-, anxiety-, and ODD symptoms. By teacher report, EL was significantly correlated only with hyperactivity-impulsivity. CONCLUSION: EL appears identifiable in young preschoolers and was particularly associated with ODD in children with ADHD symptoms.

• Abel, Marianne Hope; Ystrøm, Eivind; Caspersen, Ida Henriette; Meltzer, Helle Margrete; Aase, Heidi; Torheim, Liv Elin; Askeland, Ragna Bugge; Reichborn-Kjennerud, Ted & Brantsæter, Anne Lise (2017). Maternal iodine intake and offspring attention-deficit/hyperactivity disorder: Results from a large prospective cohort study. Nutrients.  ISSN 2072-6643.  9(11) . doi: 10.3390/nu9111239 Fulltekst i vitenarkiv.
• Bendiksen, Bothild; Svensson, Elisabeth; Aase, Heidi; Reichborn-Kjennerud, Ted; Friis, Svein; Myhre, Anne Margrethe & Zeiner, Pål (2017). Co-Occurrence of ODD and CD in Preschool Children With Symptoms of ADHD. Journal of Attention Disorders.  ISSN 1087-0547.  21(9), s 741- 752 . doi: 10.1177/1087054714538655
• Eilertsen, Espen Moen; Gjerde, Line C.; Reichborn-Kjennerud, Ted; Ørstavik, Ragnhild; Knudsen, Gun Peggy; Stoltenberg, Camilla; Czajkowski, Nikolai Olavi; Røysamb, Espen; Kendler, Kenneth S & Ystrøm, Eivind (2017). Maternal alcohol use during pregnancy and offspring attention-deficit hyperactivity disorder (ADHD): a prospective sibling control study. International Journal of Epidemiology.  ISSN 0300-5771.  46(5), s 1633- 1640 . doi: 10.1093/ije/dyx067 Fulltekst i vitenarkiv.
• Gervin, Kristina; Nordeng, Hedvig Marie Egeland; Ystrøm, Eivind; Reichborn-Kjennerud, Ted & Lyle, Robert (2017). Long-term prenatal exposure to paracetamol is associated with DNA methylation differences in children diagnosed with ADHD. Clinical Epigenetics.  ISSN 1868-7075.  9 . doi: 10.1186/s13148-017-0376-9 Fulltekst i vitenarkiv. Vis sammendrag

  Background: Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder (ADHD). The mechanism by which paracetamol may modulate the increased risk of developing ADHD is currently unknown. We have conducted an epigenome-wide association study (n = 384 cord blood samples) and investigated whether prenatal exposure to paracetamol is associated with DNA methylation in children diagnosed with ADHD. Results: Analyses identified significant differences in DNA methylation (n = 6211 CpGs) associated with prenatal exposure to paracetamol for more than 20 days in children diagnosed with ADHD compared to controls. In addition, these samples were differentially methylated compared to samples with ADHD exposed to paracetamol for less than 20 days (n = 2089 CpGs) and not exposed to paracetamol (n = 193 CpGs). Interestingly, several of the top genes ranked according to significance and effect size have been linked to ADHD, neural development, and neurotransmission. Gene ontology analysis revealed enrichment of pathways involved in oxidative stress, neurological processes, and the olfactory sensory system, which have previously been implicated in the etiology of ADHD. Conclusions: These initial findings suggest that in individuals susceptible to ADHD, prenatal long-term exposure to paracetamol is associated with DNA methylation differences compared to Controls.

• Gjerde, Line C.; Eilertsen, Espen Moen; Reichborn-Kjennerud, Ted; McAdams, Tom A.; Zachrisson, Henrik Daae; Zambrana, Imac Maria; Røysamb, Espen; Kendler, Kenneth S. & Ystrøm, Eivind (2017). Maternal perinatal and concurrent depressive symptoms and child behavior problems: a sibling comparison study. Journal of Child Psychology and Psychiatry and Allied Disciplines.  ISSN 0021-9630.  58(7), s 779- 786 . doi: 10.1111/jcpp.12704 Fulltekst i vitenarkiv.
• Gustavson, Kristin; Ystrøm, Eivind; Stoltenberg, Camilla; Susser, Ezra; Surén, Pål; Magnus, Per; Knudsen, Gun Peggy; Smith, George Davey; Langley, Kate; Rutter, Michael; Aase, Heidi & Reichborn-Kjennerud, Ted (2017). Smoking in pregnancy and child ADHD. Pediatrics.  ISSN 0031-4005.  139(2) . doi: 10.1542/peds.2016-2509 Fulltekst i vitenarkiv.
• Havdahl, Karoline Alexandra; Bishop, Somer L.; Surén, Pål; Øyen, Anne-Siri; Lord, Catherine; Pickles, Andrew; von Tetzchner, Stephen; Schjølberg, Synnve; Gunnes, Nina; Hornig, Mady; Lipkin, W. Ian; Susser, Ezra; Bresnahan, Michaeline; Magnus, Per; Stenberg, Nina; Reichborn-Kjennerud, Ted & Stoltenberg, Camilla (2017). The influence of parental concern on the utility of autism diagnostic instruments. Autism Research.  ISSN 1939-3792.  10(10), s 1672- 1686 . doi: 10.1002/aur.1817
• Holdø, Ingvild; Bramness, Jørgen Gustav; Handal, Marte; Torgersen, Leila; Reichborn-Kjennerud, Ted; Ystrøm, Eivind; Nordeng, Hedvig Marie Egeland & Skurtveit, Svetlana (2017). Hypnotics use in children 0-18 months: moderate agreement between mother-reported survey data and prescription registry data. Journal of Pharmaceutical Policy and Practice.  ISSN 2052-3211.  10:28, s 1- 8 . doi: 10.1186/s40545-017-0117-7 Fulltekst i vitenarkiv. Vis sammendrag

  Background Different methods in pharmacoepidemiology can be used to study hypnotic use in children. But neither questionnaire-based data nor prescription records can be considered a “gold standard”. This study aimed to investigate the agreement between mother-reported questionnaire-based data and prescription record data for hypnotic drugs in children aged 0–18 months. The agreement was compared to the agreement for a group of antiepileptic drugs. Methods Prescription record data were collected from the Norwegian prescription database for 47,413 children also surveyed in the Norwegian mother and child cohort between 2005 and 2009. Agreement between in the two data sources was calculated using Cohens Kappa. Multinomial logistic regression was used to calculate the effect of sociodemographic variables on discrepancies in data sources. Results The agreement between mother-reported and dispensed hypnotics was less than 50% for all hypnotics. Sensitivity of reporting increased with number of filled prescriptions. The agreement of antiepileptic drugs was 92.9% in the same population. Of several sociodemographic factors only paternal educational level and maternal work situation was significantly related to agreement between prescription record and survey data. Conclusion There was a moderate agreement between reported use and dispensed hypnotic drugs for infants and toddlers. Results indicate that sociodemographic factors play only a minor role in explaining discrepancy.

• Hornig, M; Bresnahan, M A; Che, X; Schultz, A F; Ukaigwe, J E; Eddy, M L; Hirtz, D; Gunnes, Nina; Lie, Kari Kveim; Magnus, Per; Mjaaland, Siri; Reichborn-Kjennerud, Ted; Schjølberg, Synnve; Øyen, Anne-Siri; Levin, B; Susser, E S; Stoltenberg, Camilla & Lipkin, W I (2017). Prenatal fever and autism risk. Molecular Psychiatry.  ISSN 1359-4184.  23(3), s 759- 766 . doi: 10.1038/mp.2017.119 Fulltekst i vitenarkiv.
• Kendler, Kenneth S; Aggen, Steven H; Gillespie, Nathan; Neale, Michael C; Knudsen, Gun Peggy; Krueger, Robert F; Czajkowski, Nikolai Olavi; Ystrøm, Eivind & Reichborn-Kjennerud, Ted (2017). The Genetic and Environmental Sources of Resemblance Between Normative Personality and Personality Disorder Traits. Journal of Personality Disorders.  ISSN 0885-579X.  31(2), s 193- 207 . doi: 10.1521/pedi_2016_30_251
• Li, Dong; Chang, Xiao; Connolly, John J.; Tian, Lifeng; Liu, Yichuan; Bhoj, Elizabeth J.; Robinson, Nora; Abrams, Debra; Li, Yun R.; Bradfield, Jonathan P.; Kim, Cecilia E.; Li, Jin; Wang, Fengxiang; Snyder, James; Lemma, Maria; Hou, Cuiping; Wei, Zhi; Guo, Yiran; Qiu, Haijun; Mentch, Frank D.; Thomas, Kelly A.; Chiavacci, Rosetta M.; Cone, Roger; Li, Bingshan; Sleiman, Patrick A.; Hakonarson, Hakon; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy; Andreassen, Ole Andreas; Espeseth, Thomas; Huckins, Laura M; Reinvang, Ivar; Steen, Vidar Martin; Le Hellard, Stephanie; Mattingsdal, Morten; Tozzi, Federica; Kiezebrink, Kirsty; Hebebrand, Johannes; Gorwood, Philip; Adan, Roger A H; Kas, Martien J H; Favaro, Angela; Santonastaso, Paolo; Fernande-Aranda, Fernando; Gratacos, Monica; Rybakowski, Filip; Dmitrzak-Weglarz, Monika; Kaprio, Jaakko; Keski-Rahkonen, Anna; Raevuori-Helkamaa, Anu; Furth, Eric F Van; Slof-Opt Landt, Margarita C T; Hudson, James I; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy S; Monteleone, Palmiero; Karwautz, Andreas; Berrettini, Wade H; Schork, Nicholas J; Ando, Tetsuya; Inoko, Hidetoshi; Esko, Tonu; Fischer, Krista; Mannik, Katrin; Metspalu, Andres; Baker, Jessica H; DeSocio, Janiece E; Hilliard, Christopher E; O'Toole, Julie K; Pantel, Jacques; Szatkiewicz, Jin P; Zerwas, Stephanie; Davis, Oliver S P; Helder, Sietske; Buhren, Katharina; Burghardt, Roland; De Zwaan, Martina; Egberts, Karin; Ehrlich, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Imgart, Hartmut; Scherag, Andre; Zipfel, Stephan; Boni, Claudette; Ramoz, Nicolas; Versini, Audrey; Danner, Unna N; Hendriks, Judith; Koeleman, Bobby P C; Ophoff, Roel A; Strengman, Eric; Van Elburg, Annemarie A; Bruson, Alice; Clementi, Maurizio; Degortes, Daniela; Forzan, Monica; Tenconi, Elena; Docampo, Elisa; Escaramis, Georgia; Jimenez-Murcia, Susana; Lissowska, Jolanta; Rajewski, Andrzej; Szeszenia-Dabrowska, Neonila; Slopien, Agnieszka; Hauser, Joanna; Karhunen, Leila; Meulenbelt, Ingrid; Slagboom, P Eline; Tortorella, Alfonso; Maj, Mario; Dedoussis, George; DIkeos, DImitris; Gonidakis, Fragiskos; Tziouvas, Konstantinos; Tsitsika, Artemis; Papezova, Hana; Slachtova, Lenka; Martaskova, Debora; Kennedy, James L; Levitan, Robert D; Yilmaz, Zeynep; Huemer, Julia; Koubek, Doris; Merl, Elisabeth; Wagner, Gudrun; Lichtenstein, Paul; Breen, Gerome; Cohen-Woods, Sarah; Farmer, Anne; McGuffin, Peter; Cichon, Sven; Giegling, Ina; Herms, Stefan; Rujescu, Dan; Schreiber, Stefan; Wichmann, H-Erich; DIna, Christian; Sladek, Rob; Gambaro, Giovanni; Soranzo, Nicole; Julia, Antonio; Marsal, Sara; Rabionet, Raquel; Gaborieau, Valerie; DIck, Danielle M; Palotie, Aarno; Ripatti, Samuli; Widen, Elisabeth; Andreassen, Ole A; Espeseth, Thomas; Lundervold, Astri; Reinvang, Ivar; Steen, Vidar M; Le Hellard, Stephanie; Mattingsdal, Morten; Ntalla, Ioanna; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Navratilova, Marie; Gallinger, Steven; Pinto, Dalila; Scherer, Stephen W; Aschauer, Harald; Carlberg, Laura; Schosser, Alexandra; Alfredsson, Lars; DIng, Bo; Klareskog, Lars; Padyukov, Leonid; Finan, Chris; Kalsi, Gursharan; Roberts, Marion; Barrett, Jeff C; Estivill, Xavier; Hinney, Anke; Sullivan, Patrick F; Zeggini, Eleftheria; Bulik, Cynthia M; Brandt, Harry; Crawford, Steve; Crow, Scott; Fichter, Manfred M; Halmi, Katherine A; Johnson, Craig; Kaplan, Allan S; La Via, Maria C; Mitchell, James; Strober, Michael; Rotondo, Alessandro; Treasure, Janet; Woodside, D Blake; Keel, Pamela K; Klump, Kelly L; Lilenfeld, Lisa; Bergen, Andrew W; Kaye, Walter & Magistretti, Pierre (2017). A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Scientific Reports.  ISSN 2045-2322.  7:3847, s 1- 9 . doi: 10.1038/s41598-017-01674-8
• Long, Elizabeth C.; Aggen, Steven H.; Neale, Michael Churton; Knudsen, Gun Peggy; Krueger, Robert Frederick; South, Susan Carol; Czajkowski, Nikolai Olavi; Nesvåg, Ragnar; Ystrøm, Eivind; Torvik, Fartein Ask; Kendler, Kenneth Seedman; Gillespie, Nathan A. & Reichborn-Kjennerud, Ted (2017). The association between personality disorders with alcohol use and misuse: A population-based twin study. Drug and Alcohol Dependence.  ISSN 0376-8716.  174, s 171- 180 . doi: 10.1016/j.drugalcdep.2017.01.022
• Mahic, Milada; Che, Xiaoyu; Susser, Ezra; Levin, Bruce; Reichborn-Kjennerud, Ted; Magnus, Per; Stoltenberg, Camilla; Chauhan, Lokendrasingh; Brisne, Thomas; Bresnahan, Michaeline; Suren, Pål; Hornig, Mady; Mjaaland, Siri & Lipkin, W. Ian (2017). Epidemiological and serological investigation into the role of gestational maternal influenza virus infection and autism spectrum disorders. mSphere.  ISSN 2379-5042.  2(3) . doi: 10.1128/mSphere.00159-17 Fulltekst i vitenarkiv.
• Mahic, Milada; Mjaaland, Siri; Bøvelstad, Hege; Gunnes, Nina; Susser, Ezra; Bresnahan, Michaeline; Øyen, Anne-Siri; Levin, Bruce; Che, Xiaoyu; Hirtz, Deborah; Reichborn-Kjennerud, Ted; Schjølberg, Synnve; Roth, Christine; Magnus, Per; Stoltenberg, Camilla; Surén, Pål; Hornig, Mady & Lipkin, W. Ian (2017). Maternal immunoreactivity to herpes simplex virus 2 and risk of autism spectrum disorder in male offspring. mSphere.  ISSN 2379-5042.  2(1) . doi: 10.1128/mSphere.00016-17 Fulltekst i vitenarkiv.

Se alle arbeider i Cristin

• Skogheim, Thea Steen; Weyde, Kjell Vegard Fjeldheim; Aase, Heidi; Engel, Stephanie M.; Suren, Pål; Øie, Merete Glenne; Biele, Guido; Reichborn-Kjennerud, Ted & Villanger, Gro Dehli (2020). Prenatal exposure to metals and associations with ADHD and ASD in children.
• Ask, Helga; Eilertsen, Espen Moen; Gjerde, Line C.; Gustavson, Kristin; Hannigan, Laurie John; Havdahl, Alexandra; McAdams, Tom A.; Hettema, John M.; Reichborn-Kjennerud, Ted; Torvik, Fartein Ask & Ystrøm, Eivind (2019). Intergenerational transmission of parental neuroticism to offspring neuroticism, depression, and anxiety.
• Ask, Helga; Eilertsen, Espen Moen; Gjerde, Line C.; Gustavson, Kristin; Hannigan, Laurie John; Havdahl, Alexandra; McAdams, Tom A.; Hettema, John M.; Reichborn-Kjennerud, Ted; Torvik, Fartein Ask & Ystrøm, Eivind (2019). Intergenerational transmission of parental neuroticism to offspring neuroticism, depression, and anxiety. Behavior Genetics.  ISSN 0001-8244.  49(6), s 548- 548 . doi: 10.1007/s10519-019-09973-8
• Ask, Helga; Hannigan, Laurie; Davies, Neil; Gustavson, Kristin; Biele, Guido; Richardson, Thomas; Cornish, Rosie; Corfield, Elizabeth; Askeland, Ragna Bugge; Tesli, Martin Steen; Tilling, Kate; Davey Smith, George; Magnus, Per; Reichborn-Kjennerud, Ted & Havdahl, Alexandra (2019). Exploring the Associations Between Health-Related Polygenic Scores and Participation in the Norwegian Mother and Child Pregnancy Cohort (MoBa).
• Askeland, Ragna Bugge; Hannigan, Laurie John; Ask, Helga; Tesli, Martin Steen; Corfield, Elizabeth; Andreassen, Ole Andreas; Davey-Smith, George; Reichborn-Kjennerud, Ted & Havdahl, Alexandra (2019). Early manifestations of genetic risk for neurodevelopmental disorders.
• Askeland, Ragna Bugge; Reichborn-Kjennerud, Ted; Hannigan, Laurie John; Ask, Helga; Tesli, Martin Steen; Corfield, Elizabeth & Havdahl, Alexandra (2019). Early manifestation of genetic risk for attention deficit/hyperactivity disorder in Norwegian children.
• Corfield, Elizabeth; Smajlagic, Dinka; Connoly, Siobhan; Hakonarsen, Hakon; Waldman, Irwin; Elia, Josephine; Heron, Elisabeth; Reichborn-Kjennerud, Ted; Haavik, Jan; Johansson, Stefan & Zayats, Tetyana (2019). Parent-of-origin and maternal effects in attention deficit hyperactivity disorder..
• Gjerde, Line C.; Eilertsen, Espen Moen; Hannigan, Laurie; Eley, T.C.; Røysamb, Espen; Reichborn-Kjennerud, Ted; Rijsdijk, Frühling V.; McAdams, Tom A. & Ystrøm, Eivind (2019). To what extent can passive genetic transmission account for associations between maternal depressive symptoms and child early life psychopathology symptoms?.
• Gjerde, Line C.; Eilertsen, Espen Moen; Hannigan, Laurie; Eley, T.C.; Røysamb, Espen; Reichborn-Kjennerud, Ted; Rijsdijk, Frühling V.; McAdams, Tom A. & Ystrøm, Eivind (2019). To what extent can passive genetic transmission account for associations between maternal depressive symptoms and child early life psychopathology symptoms?. Behavior Genetics.  ISSN 0001-8244.  49(6), s 520- 520 . doi: 10.1007/s10519-019-09973-8
• Gustavson, Kristin; Torvik, Fartein Ask; Gjerde, Line C.; Ask, Helga; McAdams, Tom A.; Hannigan, Laurie; Reichborn-Kjennerud, Ted; Eilertsen, Espen Moen & Ystrom, Eivind (2019). Genetic and environmental contributions to comorbidity between ADHD and emotional problems in school aged children..
• Gustavson, Kristin; Torvik, Fartein Ask; Gjerde, Line C.; Ask, Helga; McAdams, Tom; Reichborn-Kjennerud, Ted; Eilertsen, Espen Moen & Ystrøm, Eivind (2019). Genetic and environmental contributions to comorbidity between ADHD and emotional problems in school aged children.
• Gustavson, Kristin; Torvik, Fartein Ask; Gjerde, Line C.; Ask, Helga; McAdams, Tom; Reichborn-Kjennerud, Ted; Eilertsen, Espen Moen & Ystrøm, Eivind (2019). Genetic and environmental contributions to comorbidity between ADHD and emotional problems in school aged children. Behavior Genetics.  ISSN 0001-8244.  49(6), s 544- 544 . doi: 10.1007/s10519-019-09973-8
• Hannigan, Laurie; Askeland, Ragna Bugge; Ask, Helga; Tesli, Martin Steen; Corfield, Elizabeth; Mcadams, Tom; Øyen, Anne-Siri; Davey-Smith, George; Reichborn-Kjennerud, Ted & Havdahl, Alexandra (2019). Perinatal maternal stress and early-life behavioural and emotional problems: examining the role of genetically-influenced environmental sensitivity in mothers and offspring.
• Havdahl, Alexandra; Laurie, Hannigan; Askeland, Ragna Bugge; Ask, Helga; Tesli, Martin Steen; Corfield, Elizabeth; Øyen, Anne-Siri; Andreassen, Ole; Davey Smith, George & Reichborn-Kjennerud, Ted (2019). Polygenic Risk for ADHD and Exposures During Pregnancy in the Norwegian Mother and Child Cohort Study (MoBa). Vis sammendrag

  Background: Over the past decade, there has been an increase in studies showing associations between a broad range of lifestyle factors (e.g., smoking and alcohol intake) and health-related exposures (e.g., gestational diabetes) in pregnant women and ADHD in their children. It is, however, unclear whether the observed associations are causal or not. They may reflect confounding by unmeasured shared familial factors that influence both the maternal exposure and offspring ADHD. In the present study we assess the potential contribution of maternal polygenic risk for ADHD to pregnancy exposures linked to this disorder. Methods: We use data from the Norwegian Mother and Child pregnancy cohort study (MoBa), a prospective population-based pregnancy cohort study conducted by the Norwegian Institute of Public Health. Participants were recruited from all over Norway from 1999-2008. The women consented to participation in 40.6 % of the pregnancies. The cohort now includes 114,500 children, 95,200 mothers and 75,200 fathers. Blood samples were obtained from both parents during pregnancy and from mothers and children (umbilical cord) at birth. Genotyping is ongoing. A wide range of pregnancy exposures have been measured through the Medical Birth Registry and questionnaires. Summary statistics from the largest available genome-wide association study of ADHD (Demontis et al., 2019) were used to calculate polygenic risk scores (PRS). Results: Preliminary results from up to 9,073 mothers with available genotype and pregnancy exposure data suggest that maternal PRS for ADHD is associated with a range of pregnancy exposures, including smoking, coffee intake, non-use of nutritional supplements and use of pain medications. At WCPG, results will be presented from analyses of more than 20,000 mothers. For comparison purposes, associations between ADHD PRS and lifestyle and health-related factors in fathers (n>20,000) will be shown. Finally, we will present analyses of the extent to which accounting for genetic confounding attenuates associations between maternal pregnancy exposures and offspring ADHD in the MoBa cohort. Discussion: The results indicate that observed associations between pregnancy exposures and offspring ADHD could at least partly be explained by shared genetic influences/gene-environment correlations. Disclosure: Nothing to disclose.

• Lupattelli, Angela; Mahic, Milada; Handal, Marte; Ystrøm, Eivind; Reichborn-Kjennerud, Ted & Nordeng, Hedvig Marie Egeland (2019). Risk of attention deficit hyperactivity disorder in childhood after exposure to serotonergic antidepressants in pregnancy. Pharmacoepidemiology and Drug Safety.  ISSN 1053-8569.
• McAdams, Tom A.; Hannigan, Laurie John; Eilertsen, Espen Moen; Gjerde, Line C.; Reichborn-Kjennerud, Ted; Eley, Thalia C.; Rijsdijk, Frühling V. & Ystrøm, Eivind (2019). Is it time to reevaluate prenatal mental health? – Author's reply. Lancet psychiatry.  ISSN 2215-0374.  6(2), s 93- 94 . doi: 10.1016/S2215-0366(19)30004-5
• Seglem, Karoline Brobakke; Torvik, Fartein Ask; Røysamb, Espen; Gjerde, Line C.; Magnus, Per; Reichborn-Kjennerud, Ted; Svedberg, Pia; Vollrath, Margarete E. & Ørstavik, Ragnhild (2019). Education, lifestyle and life course differences in Level of work incapacity - genes and environment.
• Skurtveit, Svetlana; Kiselev, Yury; Handal, Marte; Stoltenberg, Camilla; Reichborn-Kjennerud, Ted; Suren, Pål; Havdahl, Alexandra & Hjellvik, Vidar (2019). Co-Occurring Neuropsychiatric Diagnoses and Use of Psychotropic Drugs in Children with Autism Spectrum Disorder. Pharmacoepidemiology and Drug Safety.  ISSN 1053-8569. . doi: 10.10002/pds.4864
• Tesli, Martin Steen; Corfield, Elizabeth; Zayats, Tetyana; Ask, Helga; Askeland, Ragna Bugge; Hannigan, Laurie; Robinson, Elise; Andreassen, Ole Andreas; Havdahl, Alexandra & Reichborn-Kjennerud, Ted (2019). Investigation of shared genetic risk between cardiometabolic morbidity and ADHD in a Norwegian family cohort using polygenic transmission disequilibrium test.
• Eilertsen, Espen Moen; Hannigan, Laurie John; McAdams, Tom A.; Rijsdijk, Fruhling; Czajkowski, Nikolai Olavi; Reichborn-Kjennerud, Ted; Ystrøm, Eivind & Gjerde, Line C. (2018). Parental prenatal depression and offspring ADHD: a genetically informed intergenerational study. Behavior Genetics.  ISSN 0001-8244.  s 469- 469
• Eilertsen, Espen Moen; Hannigan, Laurie John; Mcadams, Tom; Rijsdijk, Fruhling; Czajkowski, Nikolai Olavi; Reichborn-Kjennerud, Ted; Ystrøm, Eivind & Gjerde, Line C. (2018). Parental prenatal depression and offspring ADHD: A genetically informed intergenerational study.
• Gjerde, Line C.; Eilertsen, Espen Moen; Rosenström, Tom Henrik; Reichborn-Kjennerud, Ted; McAdams, Tom A.; Eley, T.C. & Ystrøm, Eivind (2018). The genetic and environmental structure of psychopathology spectra in middle childhood. Behavior Genetics.  ISSN 0001-8244.  s 473- 474
• Gjerde, Line C.; Eilertsen, Espen Moen; Rosenström, Tom Henrik; Reichborn-Kjennerud, Ted; Røysamb, Espen; McAdams, Tom A.; Eley, Thalia C. & Ystrøm, Eivind (2018). The Joint Structure of Psychopathology and Personality in Preadolescent Children – Preliminary Findings.
• Havdahl, Alexandra; Bishop, Somer L.; Farmer, Cristan; Schjølberg, Synnve; Bresnahan, Michaeline; Hirtz, Deborah; Hornig, Mady; Lord, Catherine; Reichborn-Kjennerud, Ted; Suren, Pål; Øyen, Anne-Siri; Magnus, Per; Susser, Ezra; Lipkin, W. Ian; Stoltenberg, Camilla; Davey Smith, George & Thurm, Audrey (2018). Loss of Social-Communication Skills and Outcomes during Childhood in a Large General Population Cohort.
• Huckins, Laura Marianne; Hatzikotoulas, Konstantinos; Southam, Lorraine; Thornton, Laura M.; Steinberg, Julia; Aguilera, Fernando Riveros McKay; Treasure, Janet; Schmidt, Ulrike; Gunasinghe, Cerisse; Romero, Alvin; Curtis, Charles; Rhodes, Daniela; Moens, J.; Kalsi, Gursharan; Dempster, David; Leung, Rufina; Keohane, Aofie; Burghardt, Roland; Ehrlich, Stefan; Hebebrand, Johannes; Hinney, Anke; Ludolph, Albert; Walton, Esther; Deloukas, Panagiotis; Hofman, Albert; Palotie, Aarno; Palta, Priit; van Rooij, Frank J. A.; Stirrups, Kathleen; Adan, Roger A. H.; Boni, C.; Cone, Roger; Dedoussis, George; van Furth, Eric F.; Gonidakis, Fragiskos; Gorwood, Philip; Hudson, James I.; Kaprio, Jaakko; Kas, Martien J.; Keski-Rahonen, Anna; Kiezebrink, Kirsty; Knudsen, Gun Peggy S.; Maj, Mario; Monteleone, Alessio Maria; Monteleone, Palmiero; Raevuori, Anu; Reichborn-Kjennerud, Ted; Tozzi, Federica; Tsitsika, Artemis; van Elburg, Annemarie A.; Collier, Darnesha; Sullivan, Patrick F.; Breen, Gerome; Bulik, Cynthia M. & Zeggini, Eleftheria (2018). Correction to: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa (Molecular Psychiatry, (2018), 23, 5, (1169-1180), 10.1038/mp.2017.88). Molecular Psychiatry.  ISSN 1359-4184.  23(9) . doi: 10.1038/mp.2017.202
• Mcadams, Tom; Hannigan, Laurie John; Eilertsen, Espen Moen; Gjerde, Line C.; Reichborn-Kjennerud, Ted; Eley, Thalia C.; Rijsdijk, Fruhling & Ystrøm, Eivind (2018). Maternal prenatal depression as a risk factor for early-life psychopathology in offspring: results from a genetically-informative, population-based sample.
• Reichborn-Kjennerud, Ted (2018). Understanding development of mental health problems in the population utilizing large-scale health data and novel molecular genetic methods.
• Reichborn-Kjennerud, Ted (2018). Understanding development of mental health problems in the population utilizing large-scale health data and novel molecular genetic methods.
• Reneflot, Anne; Aarø, Leif Edvard; Aase, Heidi; Reichborn-Kjennerud, Ted; Tambs, Kristian & Øverland, Simon Nygaard (red.) (2018). Psykisk helse i Norge.
• Villanger, Gro Dehli; Ystrøm, Eivind; Engel, Stephanie M.; Longnecker, Matthew P; Zoeller, R. Thomas; Pettersen, Rolf D.; Rowe, Alexander D.; Jørgensen, Jens Veilemand; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy; Zeiner, Pål & Aase, Heidi (2018). Neonatal thyroid stimulating hormone and relationship with childhood ADHD.
• Ystrøm, Eivind; Eilertsen, Espen Moen; Gjerde, Line C.; Rijsdijk, Fruhling; Gustavson, Kristin; Ask, Helga; Reichborn-Kjennerud, Ted & Mcadams, Tom (2018). Assortative mating and intergenerational transmission of ADHD.
• Ystrøm, Eivind; Eilertsen, Espen Moen; Gjerde, Line C.; Rijsdijk, Fruhling; Gustavson, Kristin; Ask, Helga; Reichborn-Kjennerud, Ted & Mcadams, Tom (2018). Assortative mating and intergenerational transmission of ADHD. Behavior Genetics.  ISSN 0001-8244.  48(6), s 524- 524
• Ørbeck, Beate; Aase, Heidi; Zeiner, Pål; Furu, Kari; Reichborn-Kjennerud, Ted & Øvergaard, Kristin Romvig (2018). ADHD medication in children: Preliminary findings from a prospective cohort study.
• Abel, Marianne Hope; Ystrøm, Eivind; Caspersen, Ida Henriette; Aase, Heidi; Torheim, Liv Elin; Meltzer, Helle Margrete; Askeland, Ragna Bugge; Reichborn-Kjennerud, Ted & Brantsæter, Anne Lise (2017). Maternal use of iodine-containing supplements in pregnancy is associated with increased risk of child attention-deficit/hyperactivity disorder.
• Lund, Ingunn Olea; Eilertsen, Espen Moen; Gjerde, Line C.; Røysamb, Espen; Wood, Mollie; Reichborn-Kjennerud, Ted & Ystrøm, Eivind (2017). Prenatal Exposure to Alcohol and Child Internalizing and Externalizing Problems.
• Mahic, Milada; Mjaaland, Siri; Bøvelstad, Hege Marie; Gunnes, Nina; Susser, Ezra; Bresnahan, Michaeline; Øyen, Anne-Siri; Levin, Bruce; Che, Xiaoyu; Hirtz, Deborah; Reichborn-Kjennerud, Ted; Schjølberg, Synnve; Roth, Christine; Magnus, Per; Stoltenberg, Camilla; Suren, Pål; Hornig, Mady & Lipkin, W. Ian (2017). Correction: Maternal immunoreactivity to herpes simplex virus 2 and risk of autism spectrum disorder in male offspring [mSphere, 2, 1, (2017) (e00016-17)] DOI:10.1128/mSphere.00016-17. mSphere.  ISSN 2379-5042.  2:e00154-17(2), s 1- 1 . doi: 10.1128/mSphere.00154-17

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