Erlend Tuseth Aasheim

• Lyshol, Heidi; Gunnarson, MR & AASHEIM, ERLEND T. (2025). Aerosol versus dry powder inhaler prescriptions in Norway, 2004-2023. European Journal of Public Health. ISSN 1101-1262. 35(Supplement_4). doi: 10.1093/eurpub/ckaf161.950. Fulltekst i vitenarkiv Vis sammendrag

  Abstract Background Many countries have committed to reducing the carbon footprints of their health systems. Pressurized metered dose inhalers (pMDI) for treating asthma and COPD are usually powered by fluorinated gases, which are powerful greenhouse gases (GHGs). Dry powder inhalers (DPIs) can provide an equivalent clinical effect in many adult patients, with greatly reduced GHG emissions. Methods All data on inhaler prescriptions during 2004-2023 are available in the Norwegian Prescription Database. We analysed the inhaler prescriptions for Salbutamol (18.4% of inhalers in 2023), as such products exist as both pMDIs and DPIs and were sold throughout 2004-2023. Results The proportion of pMDI Salbutamol prescriptions during 2004-2023 increased from 44.7% to 58.6%; with an increase observed in all counties and an absolute difference of around 20% from high to low prescribing counties. In 2023, all pMDIs with salbutamol distributed in Norway released the CO2-equivalent of driving 20 000 000 km in a small petrol-driven car. In the age group 10-19 years (mainly children who cannot make medical choices on their own) the proportion using pMDIs during 2004-2023 increased from 30% to 67%. In the age group 20-59 years, the proportion of pMDI Salbutamol use in 2004/2023 was 45%/54%. If 50% of users aged 20-59 changed from pMDI to DPI, the reduced emissions for Salbutamol-use alone in 2023 would have been equivalent to driving 1 640 000 km in a small car. Conclusions In Norway the proportion of Salbutamol inhalers prescriptions with fluorinated gas propellants increased from 2004 to 2023, with county differences unlikely to be fully explained by case mix differences. The observed prescription patterns over time and across counties suggest a need to analyse inhaler prescription data in a full data set. This will both inform clinicians and policy makers about variations in clinical practice and enable estimates of potential GHG reductions through a modified prescription practice. Key messages • To reduce GHG emissions from the health sector, monitoring of emission sources is needed. • In Norway, inhaler prescriptions might be a low-hanging fruit in reducing health sector emissions.

• Lindholm, Espen; Hegde, Inger Johanne; Saltnes, Cathrine; Leonardsen, Ann-Chatrin Linqvist & AASHEIM, ERLEND T. (2023). Climate change, sustainability and anesthesiology practice: A national survey among anesthesiologists and nurse anesthetists in Norway. The Journal of Climate Change and Health. 13, s. 1–8. doi: 10.1016/j.joclim.2023.100259. Fulltekst i vitenarkiv Vis sammendrag

  Background: In the face of climate change the health sector will need to tackle both the increasing consequen- ces for health worldwide and to reduce its own carbon footprint, which is estimated at 4.4% of global emis- sions. Raising the voice of health professionals has been identified as paramount to achieving the wide-scale and urgent response required to limit the consequences of climate change for health. Among health profes- sionals, anesthetic practitioners are ideally placed to lead the way given that they make daily decisions regarding anesthetic gasses with a considerable footprint on climate and the environment. Methods: Here, we describe a cross-sectional nationwide survey among 3,300 anesthesiologists and nurse anesthetists in Norway, focusing on climate change, health, and sustainable anesthetic care. Responses were tabulated and characterized using descriptive statistics. Results: A large majority of the responding anesthesiologists and nurse anesthetists (n = 697, response rate 21.1%) agreed or strongly agreed that the world is facing a climate crisis; that nurses and doctors have a par- ticular responsibility to warn about health threats; and that health organizations should limit their impact on climate and the environment. We found that desflurane is still widely used in Norway, despite its high cli- mate footprint. We also identified several barriers to development of sustainable anesthetic care, including a lack of easy access to waste management systems, an absence of guidelines which promote sustainable care, and inadequate means for disposal of drug residues. Conclusions: Alongside other surveys, the present survey identifies safe and feasible adjustments to anes- thetic practice which can give substantial emission reductions, pave the way for a wider health sector response, and yield considerable benefits to planetary health.

• AASHEIM, ERLEND T.; Bhopal, Anand; O’Brien, Karen; Lie, Anne Kveim; Nakstad, Espen Rostrup & Andersen, Lene Frost [Vis alle 9 forfattere av denne artikkelen] (2023). Climate change and health: a 2-week course for medical students to inspire change. The Lancet Planetary Health. 7. doi: 10.1016/S2542-5196(22)00304-7. Fulltekst i vitenarkiv
• Hewitt, Stephen I; Kristinsson, Jon Adalsteinn; Aasheim, Erlend T.; Høgestøl, Ingvild Kristine; Aaseth, Eirik & Jahnsen, Jørgen [Vis alle 8 forfattere av denne artikkelen] (2020). Relationships Between Vitamin D Status and PTH over 5 Years After Roux-en-Y Gastric Bypass: a Longitudinal Cohort Study. Obesity Surgery. ISSN 0960-8923. 30(9), s. 3426–3434. doi: 10.1007/s11695-020-04582-5. Fulltekst i vitenarkiv Vis sammendrag

  Abstract Purpose Secondary hyperparathyroidism (SHPT) after obesity surgery may affect bone health. Optimal vitamin D levels have not been established to prevent SHPT postoperatively. We investigated whether SHPT differed across threshold levels of serum 25-hydroxyvitamin D (S-25(OH)D) from 6 months up to 5 years after Roux-en-Y gastric bypass (RYGB). Materials and Methods We included 554 patients at follow-up 5 years postoperatively. Blood samples were analysed for S-25(OH)D, ionized calcium (iCa) and parathyroid hormone (PTH) during follow-up. Results PTH and prevalence of SHPT increased from 6 months to 5 years postoperatively, while S-25(OH)D and iCa decreased (all P < 0.001). PTH and SHPT development are related with S-25(OH)D, and PTH differed between all subgroups of S-25(OH)D. SHPT occurred less frequently across all subgroups of S-25(OH)D ≥ 50 nmol/l during follow-up: odds ratio (OR) 0.44 (95% CI 0.36–0.54) in patients with S-25(OH)D ≥ 50 nmol/l, OR 0.38 (0.30–0.49) with S-25(OH)D ≥ 75 nmol/l and OR 0.19 (0.12–0.31) with S-25(OH) D ≥ 100 nmol/l, all compared with S-25(OH)D < 50 nmol/l. At 5 years, 208/554 patients (38%) had SHPT; SHPT was found in 94/188 patients (50%) with S-25(OH)D < 50 nmol/l, in 69/222 (31%) with S-25(OH)D 50–74 nmol/l, in 40/117 (34%) with S-25(OH)D 75–99 nmol/l and in 5/27 (19%) with S-25(OH)D ≥ 100 nmol/l. An interaction existed between S-25(OH)D and iCa. Bone alkaline phosphatase remained increased with SHPT. Conclusions A significant relationship existed between S-25(OH)D and development of PTH and SHPT. The prevalence of SHPT was lower with threshold levels 25(OH)D ≥ 50 nmol/l and ≥ 75 nmol/l over the 5 years, and lowest with S-25(OH)D ≥ 100 nmol/l. Keywords Bariatric surgery . Morbid obesity . Vitamin D . Calcium . Parathyroid hormone . Bone turnover

• Hewitt, Stephen I; AASHEIM, ERLEND T.; Søvik, Torgeir Thorson; Jahnsen, Jørgen; Kristinsson, Jon Adalsteinn & Eriksen, Erik Fink [Vis alle 7 forfattere av denne artikkelen] (2018). Relationships of serum 25-hydroxyvitamin D, ionized calcium and parathyroid hormone after obesity surgery. Clinical Endocrinology. ISSN 0300-0664. 88(3), s. 372–379. doi: 10.1111/cen.13531. Fulltekst i vitenarkiv
• Valderhaug, Tone Gretland; AASHEIM, ERLEND T.; Sandbu, Rune; Jakobsen, Gunn Signe; Småstuen, Milada C & Hertel, Jens Kristoffer [Vis alle 7 forfattere av denne artikkelen] (2016). The association between severity of King’s Obesity Staging Criteria scores and treatment choice in patients with morbid obesity: a retrospective cohort study. BMC Obesity. 3(51). doi: 10.1186/s40608-016-0133-1. Fulltekst i vitenarkiv Vis sammendrag

  Background The King’s Obesity Staging Criteria (KOSC) comprises of a four-graded set of health related domains. We aimed to examine whether, according to KOSC, patients undergoing bariatric surgery differed from those opting for conservative treatment. Methods We graded 2142 consecutive patients with morbid obesity attending our centre from 2005-10 into the following KOSC domains: airway/apnoea, body mass index (BMI), cardiovascular risk (CV-risk), diabetes mellitus, economic complications, functional limitations, gonadal dysfunction, and perceived health status/body image. Both patients and physicians agreed upon treatment choice through a shared decision making process. Results A total of 1329 (62%) patients opted for lifestyle intervention and 813 (37%) for bariatric surgery as their first treatment choice. The patients treated with bariatric surgery were younger (42 vs. 44 years, p < 0.001), had a higher BMI (45.4 vs. 43.8 kg/m2, p < 0.001) and had a lower ten year estimated CV-risk (9.4 vs. 10.7%, p = 0.004) than the lifestyle intervention group. Compared with having BMI < 40 kg/m2, BMI ≥ 40 kg/m2 was associated with 85% increased odds of bariatric surgery (OR 1.85 [95% CI 1.48, 2.30]). Conversely, patients with ≥20% ten year CV-risk, had lower odds of bariatric surgery than patients with <20% CV-risk (0.68 [0.53, 0.87]). Conclusion BMI was the strongest KOSC-domain associated with subsequent bariatric surgery after a shared decision making process. Prospective studies are required to assess whether the use of KOSC can help guide patients and clinicians to identify the most appropriate choice of treatment for morbid obesity.

• Risstad, Hilde; Svanevik, Marius; Kristinsson, Jon Adalsteinn; Hjelmesæth, Jøran; AASHEIM, ERLEND T. & Hofsø, Dag [Vis alle 11 forfattere av denne artikkelen] (2016). Standard vs distal roux-en-Y gastric bypass in patients with body mass index 50 to 60 a double-blind, randomized clinical trial. JAMA Surgery. ISSN 2168-6254. 151(12), s. 1146–1155. doi: 10.1001/jamasurg.2016.2798. Fulltekst i vitenarkiv
• Aaseth, Eirik; Fagerland, Morten; Aas, Anne-Marie; Hewitt, Stephen I; Risstad, Hanne & Kristinsson, Jon Adalsteinn [Vis alle 9 forfattere av denne artikkelen] (2015). Vitamin concentrations 5 years after gastric bypass. European Journal of Clinical Nutrition. ISSN 0954-3007. 69, s. 1249–1255. doi: 10.1038/ejcn.2015.82. Fulltekst i vitenarkiv Vis sammendrag

  Background/Objectives: Few studies have investigated the effects of bariatric surgery on vitamin status in the long term. We examined changes in vitamin status up to 5 years after Roux-en-Y gastric bypass surgery. Subjects/Methods: Using a retrospectively maintained database of patients undergoing weight loss surgery, we identified all patients operated with Roux-en-Y gastric bypass at our tertiary care hospital during July 2004–May 2008. Data on vitamin concentrations and patient-reported intake of dietary supplements were collected up to July 2012. Linear mixed models were used to estimate changes in vitamin concentrations during follow-up, adjusting for age and sex. All patients were recommended daily oral multivitamin, calcium/vitamin D and iron supplements and 3-monthly intramuscular B-12 after surgery. Results: Out of the 443 patients operated with gastric bypass, we included 441 (99.5%) patients with one or more measurements of vitamin concentrations (75.1% women; mean age 41.5 years, mean body mass index 46.1 kg/m2 at baseline). At 5 years after surgery, the patients' estimated mean vitamin concentrations were either significantly higher (vitamin B-6, folic acid, vitamin B-12, vitamin C and vitamin A) or not significantly different (thiamine, 25-hydroxyvitamin D and lipid-adjusted vitamin E) compared with before surgery. Use of multivitamin, calcium/vitamin D and vitamin B-12 supplements was reported by 1–9% of patients before surgery, 79–84% of patients at 1 year and 52–83% of patients 5 years after surgery. Conclusions: In patients who underwent gastric bypass surgery, estimated vitamin concentrations were either significantly increased or unchanged up to 5 years after surgery.

• Risstad, Hilde; Søvik, Torgeir Thorson; Engström, My; AASHEIM, ERLEND T.; Fagerland, Morten & Olsén, Monika Fagervik [Vis alle 12 forfattere av denne artikkelen] (2015). Five-year outcomes after laparoscopic gastric bypass and laparoscopic duodenal switch in patients with body mass index of 50 to 60: A randomized clinical trial. JAMA Surgery. ISSN 2168-6254. 150(4), s. 352–361. doi: 10.1001/jamasurg.2014.3579. Fulltekst i vitenarkiv
• Hewitt, Stephen; Hummerfeldt, Sjur; Søvik, Torgeir Thorson; AASHEIM, ERLEND T.; Risstad, Hilde & Kristinsson, Jon Adalsteinn [Vis alle 7 forfattere av denne artikkelen] (2014). Long-term improvements in pulmonary function 5 years after bariatric surgery. Obesity Surgery. ISSN 0960-8923. 24(5), s. 705–711. doi: 10.1007/s11695-013-1159-9. Fulltekst i vitenarkiv
• Gjersvik, Petter; Gulbrandsen, Pål; AASHEIM, ERLEND T. & Nylenna, Magne (2013). Dårlig tittel - dårlig manus? Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 133, s. 2475–2477. doi: 10.4045/tidsskr.13.1077. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Karlsson, Jan; AASHEIM, ERLEND T.; Fagerland, Morten; Bjorkman, Sofia & Engstrom, My [Vis alle 9 forfattere av denne artikkelen] (2013). Gastrointestinal function and eating behavior after gastric bypass and duodenal switch. Surgery for Obesity and Related Diseases. ISSN 1550-7289. 9(5), s. 641–647. doi: 10.1016/j.soard.2012.06.006. Fulltekst i vitenarkiv
• Hewitt, Stephen; Søvik, Torgeir Thorson; AASHEIM, ERLEND T.; Kristinsson, Jon Adalsteinn; Jahnsen, Jørgen & Birketvedt, Grethe [Vis alle 9 forfattere av denne artikkelen] (2013). Secondary Hyperparathyroidism, Vitamin D Sufficiency, and Serum Calcium 5 Years After Gastric Bypass and Duodenal Switch. Obesity Surgery. ISSN 0960-8923. 23(3), s. 384–390. doi: 10.1007/s11695-012-0772-3. Fulltekst i vitenarkiv
• Johnson, Line Kristin; Andersen, Lene Frost; Hofsø, Dag; AASHEIM, ERLEND T.; Holven, Kirsten Bjørklund & Sandbu, Rune [Vis alle 8 forfattere av denne artikkelen] (2013). Dietary changes in obese patients undergoing gastric bypass or lifestyle intervention: A clinical trial. British Journal of Nutrition. ISSN 0007-1145. 110(1), s. 127–134. doi: 10.1017/S0007114512004631. Fulltekst i vitenarkiv
• Wium, Cecilie; AASHEIM, ERLEND T.; Ueland, Thor; Michelsen, Annika; Thorsby, Per Medbøe & Larsen, Ingegerd Frøyshov [Vis alle 9 forfattere av denne artikkelen] (2013). Differences in insulin sensitivity, lipid metabolism and inflammation between young adult Pakistani and Norwegian patients with type 2 diabetes: a cross sectional study. BMC Endocrine Disorders. 13(49). doi: 10.1186/1472-6823-13-49. Fulltekst i vitenarkiv Vis sammendrag

  Background Immigrants from South Asia to Western countries have a high prevalence of type 2 diabetes mellitus (T2DM). We explored pathogenic factors that might contribute to the high risk of T2DM in Pakistani immigrants to Norway. Methods A cross-sectional study was performed in 18 Pakistani and 21 Norwegian men and women with T2DM (age 29 – 45 years), recruited from two hospital out-patient clinics. Anthropometrics and a two-step euglycemic, hyperinsulinemic clamp with measurements of non-esterified fatty acids (NEFA) during clamp, was performed in all patients. Insulin sensitivity, given as the Glucose Infusion Rate (GIR) and Insulin Sensitivity Index (ISI), was calculated from the two euglycemic clamp steps. Fasting adipokines and inflammatory mediators were measured. Continuous variables between groups were compared using Student’s t test or Mann–Whitney U test as appropriate. Spearman’s correlation coefficient and multiple linear regression analyses were used. Results Despite having a lower BMI, Pakistani patients were more insulin resistant than Norwegian patients, during both low and high insulin infusion rates, after adjustment for sex and % body fat: median (interquartile range) GIR(low insulin): 339.8(468.0) vs 468.4(587.3) µmol/m2/min (p=0.060), ISI(low insulin): 57.1(74.1) vs 79.7(137.9) µmol/m2/min (p=0.012), GIR(high insulin): 1661.1(672.3) vs 2055.6(907.0) µmol/m2/min (p=0.042), ISI(high insulin): 14.2(7.3) vs 20.7(17.2) µmol/m2/min (p=0.014). Pakistani patients had lower percentage NEFA suppression 30 minutes into clamp hyperinsulinemia than Norwegians: 41.9(90.6)% vs 71.2(42.1)%, (p=0.042). The relationship of ISI to BMI, leptin and interleukin-1 receptor antagonist also differed between Norwegians and Pakistanis. Conclusions Compared with Norwegian patients, Pakistani patients with T2DM had lower insulin sensitivity, affecting both glucose and lipid metabolism. The relation of insulin sensitivity to BMI and some adipokines also differed between the groups. Keywords: Ethnicity; South Asian; Insulin sensitivity; Anthropometry; NEFA; Adipokines; Inflammation

• Pournaras, D J; AASHEIM, ERLEND T.; Søvik, Torgeir Thorson; Andrews, Richard; Mahon, D & Welbourn, R [Vis alle 8 forfattere av denne artikkelen] (2012). Effect of the definition of type II diabetes remission in the evaluation of bariatric surgery for metabolic disorders. British Journal of Surgery. ISSN 0007-1323. 99(1), s. 100–103. doi: 10.1002/bjs.7704. Fulltekst i vitenarkiv
• Haukeland, John Willy; Dahl, Tuva Børresdatter; Yndestad, Arne; Gladhaug, Ivar Prydz; Løberg, Else Marit & Haaland, Therese Kristina [Vis alle 13 forfattere av denne artikkelen] (2012). Fetuin A in nonalcoholic fatty liver disease: in vivo and in vitro studies. European Journal of Endocrinology (EJE). ISSN 0804-4643. 166(3), s. 503–510. doi: 10.1530/EJE-11-0864. Fulltekst i vitenarkiv
• Johnson, Line Kristin; Hofsø, Dag; AASHEIM, ERLEND T.; Tanbo, Tom Gunnar; Holven, Kirsten Bjørklund & Andersen, Lene Frost [Vis alle 8 forfattere av denne artikkelen] (2012). Impact of gender on vitamin D deficiency in morbidly obese patients: a cross-sectional study. European Journal of Clinical Nutrition. ISSN 0954-3007. 66(1), s. 83–90. doi: 10.1038/ejcn.2011.140. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Johnson, Line Kristin; Hofsø, Dag; Bøhmer, Thomas & Hjelmesæth, Jøran (2012). Vitamin status after gastric bypass and lifestyle intervention: a comparative prospective study. Surgery for Obesity and Related Diseases. ISSN 1550-7289. 8(2), s. 169–175. doi: 10.1016/j.soard.2011.01.038. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; AASHEIM, ERLEND T.; Taha, Osama; Engstrom, My; Fagerland, Morten & Bjorkman, Sofia [Vis alle 10 forfattere av denne artikkelen] (2011). Weight Loss, Cardiovascular Risk Factors, and Quality of Life After Gastric Bypass and Duodenal Switch A Randomized Trial. Annals of Internal Medicine. ISSN 0003-4819. 155(5), s. 281–U34. doi: 10.7326/0003-4819-155-5-201109060-00005. Fulltekst i vitenarkiv
• Hofsø, Dag; AASHEIM, ERLEND T.; Søvik, Torgeir Thorson; Jakobsen, Gunn Signe; Johnson, Line Kristin & Sandbu, Rune [Vis alle 9 forfattere av denne artikkelen] (2011). Oppfølging etter fedmekirurgi. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 131, s. 1887–1892. doi: 10.4045/tidsskr.10.1463. Fulltekst i vitenarkiv Vis sammendrag

  Bakgrunn. Antall fedmeoperasjoner øker i Norge. Fedmeopererte pasienter kan få kirurgiske, medisinske og ernæringsmessige komplikasjoner. Oppfølging av pasientene er derfor viktig. Materiale og metode. Artikkelen er basert på litteratursøk i PubMed og på forfatternes erfaringer. Resultater. Fedmekirurgi medfører betydelig og varig vektreduksjon og bedring av fedmerelaterte sykdommer. Gastrisk bypass er den vanligste fedmeoperasjonen i Norge. Operasjonen er assosiert med en 30-dagers dødelighet på under 0,5 %, mens alvorlige komplikasjoner forekommer hos omtrent 5 % av pasientene. Senkomplikasjoner omfatter blant annet intern herniering, ulcussykdom og gallesteinssykdom. Etter operasjon skal pasientene få profylaktisk tilskudd av jern, vitamin D/kalsium og vitamin B12 for å forebygge vitamin- og mineralmangler. Gastrointestinale plager og postprandial hypoglykemi forekommer, men symptomene kan bedres ved endringer i kosten. Behovet for antidiabetisk og antihypertensiv medikasjon reduseres postoperativt. Dosejustering av andre medikamenter kan også være aktuelt. Graviditet frarådes det første året etter fedmekirurgi. Mange har behov for plastikkirurgiske inngrep etter et slikt inngrep. Fortolkning. Komplikasjoner etter fedmekirurgi kan debutere lenge etter operasjonen og regelmessig oppfølging er nødvendig. Fastlegene bør ha ansvaret for langtidsoppfølgingen og må ha kjennskap til vanlige og alvorlige komplikasjoner og kjenne til normale plager etter fedmekirurgi.

• Aasheim, Erlend T; Elshorbagy, Amany K; Diep, Lien My; Søvik, Torgeir Thorson; Mala, Tom & Valdivia-Garcia, Maria [Vis alle 10 forfattere av denne artikkelen] (2011). Effect of bariatric surgery on sulphur amino acids and glutamate. British Journal of Nutrition. ISSN 0007-1145. 106(3), s. 432–440. doi: 10.1017/S0007114511000201. Fulltekst i vitenarkiv Vis sammendrag

  Plasma total cysteine (tCys) concentrations are associated with BMI. To study the relationship between tCys and BMI, we monitored the changes in serum concentrations of tCys and metabolically related compounds in sixty obese patients (BMI 50–60 kg/m2) from before to 1 year after either gastric bypass surgery (mean 30 % weight loss) or duodenal switch surgery (mean 41 % weight loss). A total of fifty-eight healthy persons (BMI 17–31 kg/m2) served as controls. Before surgery, obese patients had modestly (approximately 17 %) higher mean serum tCys, and markedly (>2-fold) higher glutamate concentrations, than controls (P ≤ 0·001 for both). Serial examinations after surgery revealed that gastric bypass patients had no change in tCys concentrations (P = 0·22), while duodenal switch patients showed a modest (approximately 12 %) but significant decrease in tCys (P < 0·001). Total homocysteine concentrations increased in duodenal switch patients but not in gastric bypass patients. Independent of surgery type, serum concentrations of methionine and cystathionine decreased (P < 0·05 for both), while serum glutathione and taurine remained stable. Glutamate concentrations declined, as did γ-glutamyltransferase activity (P < 0·001 for both). These results show that despite 30 % weight loss, and decreases in methionine, cystathionine and glutamate, there was no significant change in serum tCys in patients after gastric bypass surgery. The decrease in tCys in patients undergoing duodenal switch could be related to malabsorption. The present findings do not suggest that BMI is a causal determinant of plasma tCys. © 2011 Cambridge University Press

• Søvik, Torgeir Thorson; Taha, Osama; AASHEIM, ERLEND T.; Engström, My; Kristinsson, Jon Adalsteinn & Björkman, Sofia [Vis alle 10 forfattere av denne artikkelen] (2010). Randomized clinical trial of laparoscopic gastric bypass versus laparoscopic duodenal switch for superobesity. British Journal of Surgery. ISSN 0007-1323. 97(2), s. 160–166. doi: 10.1002/bjs.6802. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Irandoust, Babak; Birkeland, Kåre I.; AASHEIM, ERLEND T.; Schou, Carl Fredrik & Kristinsson, Jon Adalsteinn [Vis alle 7 forfattere av denne artikkelen] (2010). Type 2-diabetes og metabolsk syndrom før og etter gastrisk bypass. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 130(13), s. 1347–1350. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Frigstad, Svein-Oskar; Søvik, Torgeir Thorson; Birkeland, Kåre I. & Haukeland, John Willy (2010). Hyperinsulinemic hypoglycemia and liver cirrhosis presenting after duodenal switch: a case report. Surgery for Obesity and Related Diseases. ISSN 1550-7289. 6(4), s. 441–443. doi: 10.1016/j.soard.2009.11.007. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Bjorkman, Sofia; Søvik, Torgeir Thorson; Engstrom, My; Hanvold, Susanna & Mala, Tom [Vis alle 8 forfattere av denne artikkelen] (2009). Vitamin status after bariatric surgery: a randomized study of gastric bypass and duodenal switch. American Journal of Clinical Nutrition. ISSN 0002-9165. 90(1), s. 15–22. doi: 10.3945/ajcn.2009.27583. Fulltekst i vitenarkiv
• Hjelmesæth, Jøran; Hjelmesaeth, J; Hofsø, Dag; Hofso, D; Aasheim, Erlend T & Jenssen, Trond Geir [Vis alle 11 forfattere av denne artikkelen] (2009). Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study. Cardiovascular Diabetology. 8. doi: 10.1186/1475-2840-8-7. Fulltekst i vitenarkiv Vis sammendrag

  Background: The prevalence of vitamin D insufficiency and secondary hyperparathyroidism is high among morbidly obese subjects. Further, low serum levels of 25-hydroxyvitamin D (25 [OH]D) and magnesium have been associated with increased risk of the metabolic syndrome (MS), and recently, a possible link between PTH and MS has been reported. Although it is well known that the synthesis and secretion of PTH is regulated by serum levels of calcium, phosphate, magnesium and 25(OH)D, less is known about the possible clustered affiliation of these parameters with MS. We aimed to explore whether MS is associated with abnormal serum levels of PTH, 25(OH)D and magnesium in a population of morbidly obese patients. <br> Methods: Fasting serum levels of 25(OH)D, PTH and magnesium were assessed in a cross-sectional cohort study of 1,017 consecutive morbidly obese patients (68% women). Multiple logistic regression analyses were used to assess the independent effect of PTH, 25(OH)D and magnesium on the odds for MS (National Cholesterol Education Program [NCEP]) after adjustment for confounding factors. <br> Results: Sixty-eight percent of the patients had MS. Patients with MS had lower mean serum magnesium (P < 0.001) and higher mean PTH (P = 0.067) than patients without MS, whereas mean 25(OH)D did not differ significantly. Patients with PTH levels in the second to fourth quartiles had higher odds of prevalent MS (odds ratio 1.47 [95% CI 0.92–2.35], 2.33 [95% CI 1.40–3.87] and 2.09 [95% CI 1.23–3.56], respectively), after adjustment for 25(OH)D, magnesium, calcium, phosphate, creatinine, age, gender, season of serum sampling, BMI, current smoking, albuminuria, CRP, insulin resistance and type 2 diabetes. Further, PTH was significantly correlated with systolic and diastolic pressure (both P < 0.001), but not with the other components of MS. The levels of 25(OH)D and magnesium were not associated with MS in the multivariate model. <br> Conclusion: The PTH level, but not the vitamin D level, is an independent predictor of MS in treatment seeking morbidly obese Caucasian women and men. Randomized controlled clinical trials, including different therapeutic strategies to lower PTH, e.g. calcium/vitamin D supplementation and weight reduction, are necessary to explore any cause-and-effect relationship.

• AASHEIM, ERLEND T.; Frigstad, Svein-Oskar; Søvik, Torgeir Thorson; Birkeland, Kåre I. & Haukeland, John Willy (2009). Hyperinsulinemic hypoglycemia and liver cirrhosis presenting after duodenal switch: a case report. Surgery for Obesity and Related Diseases. ISSN 1550-7289. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; AASHEIM, ERLEND T.; Kristinsson, Jon Adalsteinn; Schou, Carl Fredrik; Diep, Lien My & Nesbakken, Arild [Vis alle 7 forfattere av denne artikkelen] (2009). Establishing Laparoscopic Roux-en-Y Gastric Bypass: Perioperative Outcome and Characteristics of the Learning Curve. Obesity Surgery. ISSN 0960-8923. 19(2), s. 158–165. doi: 10.1007/s11695-008-9584-x. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Hofsø, Dag; Hjelmesæth, Jøran & Sandbu, Rune (2008). Peripheral neuropathy and severe malnutrition following duodenal switch. Obesity Surgery. ISSN 0960-8923. 12, s. 1640–1643. doi: 10.1007/s11695-008-9539-2. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. (2008). Wernicke Encephalopathy After Bariatric Surgery A Systematic Review. Annals of Surgery. ISSN 0003-4932. 248(5), s. 714–720. doi: 10.1097/SLA.0b013e3181884308. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Hofso, D; Hjelmesaeth, J; Birkeland, Kåre I. & Bøhmer, Thomas (2008). Vitamin status in morbidly obese patients: a cross-sectional study. American Journal of Clinical Nutrition. ISSN 0002-9165. 87(2), s. 362–369. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; AASHEIM, ERLEND T.; Kristinsson, Jon Adalsteinn; Schou, Carl Fredrik; Nesbakken, Arild & Mala, Tom (2007). Kirurgisk behandling av sykelig fedme ved et regionalt sentr. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 127, s. 47–49. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Mala, Tom; Søvik, Torgeir Thorson; Kristinsson, Jon Adalsteinn & Bøhmer, Thomas (2007). Kirurgisk behandling av sykelig fedme. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 127, s. 38–42. Fulltekst i vitenarkiv

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• Lindstad, Christian Borgen; Myrbakk, Torni; Fagernes, Mette; Eriksen-Volle, Hanne-Merete & Aasheim, Erlend T. (2024). Bærekraftig smittevern – av med hansken. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 144(10). doi: 10.4045/tidsskr.24.0343. Fulltekst i vitenarkiv
• Strandrud, Janne; Melsether, Silje; Brasfield, David Vernon & AASHEIM, ERLEND T. (2023). On the path to a climate-friendly health service. doi: 10.4045/tidsskr.23.038. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. (2023). Kurs om klimaendringer for legestudenter. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 143(11). doi: 10.4045/tidsskr.23.0375. Fulltekst i vitenarkiv
• Hegde, Johanne & AASHEIM, ERLEND T. (2022). Bærekraftig anestesi. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 142(15). doi: 10.4045/tidsskr.22.0612. Fulltekst i vitenarkiv
• Skagen, Knut Mork & Aasheim, Erlend Tuseth (2019). Helsepersonell må kjempe mot global oppvarming. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. Fulltekst i vitenarkiv
• Sandvik, Jorunn; Laurenius, Anna; Näslund, Ingmar; Videhult, Per; Wiren, Mikal & AASHEIM, ERLEND T. (2018). Nordiske retningslinjer for oppfølging etter fedmekirurgi. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 138(4), s. 326–327. doi: 10.4045/tidsskr.17.1106. Fulltekst i vitenarkiv Vis sammendrag

  Fedmekirurgi er effektiv behandling for personer med helseskadelig overvekt som ikke oppnår varig vektreduksjon på annen måte. Etter operasjonen er det nødvendig med daglige vitamin-mineral-tilskudd, og pasienten trenger livslang oppfølging fra helsetjenesten. Det er nå utarbeidet felles nordiske retningslinjer for oppfølgingen og for tilskudd etter fedmekirurgi.

• Valderhaug, Tone Gretland; Hjelmesæth, Jøran; Sandbu, Rune; AASHEIM, ERLEND T. & Hertel, Jens Kristoffer (2015). The utility of obesity staging classification systems in selecting persons for bariatric surgery. Fulltekst i vitenarkiv
• Valderhaug, Tone Gretland; Hjelmesæth, Jøran; Sandbu, Rune; AASHEIM, ERLEND T. & Hertel, Jens Kristoffer (2015). The utility of obesity staging classification systems in selecting persons for bariatric surgery. Obesity Facts. ISSN 1662-4025. Fulltekst i vitenarkiv
• Svanevik, Marius; Risstad, Hilde; Kristinsson, Jon Adalsteinn; Hjelmesæth, Jøran; AASHEIM, ERLEND T. & Hofsø, Dag [Vis alle 11 forfattere av denne artikkelen] (2015). Helserelatert livskvalitet og tarmfunksjon etter proksimal og distal gastrisk bypass – en dobbelt blind randomisert kontrollert studie. Fulltekst i vitenarkiv
• Risstad, Hilde; Svanevik, Marius; Kristinsson, Jon Adalsteinn; Hjelmesæth, Jøran; AASHEIM, ERLEND T. & Hofsø, Dag [Vis alle 11 forfattere av denne artikkelen] (2015). Proximal versus distal gastric bypass in patients with body mass index 50-60 kg/m2: A double-blind, randomized clinical trial. Surgery for Obesity and Related Diseases. ISSN 1550-7289. 11(6), s. S1–S2. doi: 10.1016/j.soard.2015.10.003. Fulltekst i vitenarkiv Vis sammendrag

  Patients with a body mass index (BMI, kg/m2) of 50 or more experience substantial weight loss, but often remain morbidly obese after proximal Roux’en Y gastric bypass (RYGB). We tested whether a distal RYGB improves patient outcomes in a double-blind randomized clinical trial.

• Gjersvik, Petter; Gulbrandsen, Pål; Aasheim, Erlend T. & Nylenna, Magne (2014). P. Gjersvik og medarbeidere svarer:. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 134(4), s. 382–383. doi: 10.4045/tidsskr.14.0144. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. (2010). The Alcohol Factor in Wernicke's Encephalopathy Post Bariatric Surgery Reply. Annals of Surgery. ISSN 0003-4932. 251(5), s. 993–994. doi: 10.1097/SLA.0b013e3181db38a1. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Birkeland, Kåre I. & Bøhmer, Thomas (2010). Erratum. American Journal of Clinical Nutrition. ISSN 0002-9165. 91(1), s. 239–240. Fulltekst i vitenarkiv
• Haukeland, John Willy; Zbigniew, Konopski; AASHEIM, ERLEND T.; Johansen, Odd Erik; Løberg, Else Marit & Haaland, T. [Vis alle 12 forfattere av denne artikkelen] (2010). ELEVATED LEVELS OF FETUIN A IN NONALCOHOLIC FATTY LIVER DISEASE. Journal of Hepatology. ISSN 0168-8278. 52, s. S143–S144. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Hofsø, Dag & Søvik, Torgeir Thorson (2010). Vitamin supplements after bariatric surgery. Clinical Endocrinology. ISSN 0300-0664. 72(1), s. 134–135. doi: 10.1111/j.1365-2265.2009.03611.x. Fulltekst i vitenarkiv
• Johnson, Line Kristin; Hofsø, Dag; AASHEIM, ERLEND T.; Tanbo, Tom Gunnar; Andersen, Lene Frost & Holven, Kirsten Bjørklund [Vis alle 8 forfattere av denne artikkelen] (2010). Vitamin D Deficiency in morbidly obese women and men. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; AASHEIM, ERLEND T. & Olbers, T. (2010). Randomized clinical trial of laparoscopic gastric bypass versus laparoscopic duodenal switch for superobesity (Br J Surg 2010; 97: 160-166). British Journal of Surgery. ISSN 0007-1323. 97(6), s. 960–961. doi: 10.1002/bjs.7143. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. (2009). Peculiarities of Wernicke Encephalopathy After Bariatric Surgery Reply. Annals of Surgery. ISSN 0003-4932. 249(6), s. 1066–1067. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Hofsø, Dag & Søvik, Torgeir Thorson (2009). Vitamin supplements after bariatric surgery. Clinical Endocrinology. ISSN 0300-0664. doi: 10.1111/j.1365-2265.2009.03611.x. Fulltekst i vitenarkiv
• Frigstad, Svein-Oskar; AASHEIM, ERLEND T.; Søvik, Torgeir Thorson; Birkeland, Kåre I. & Haukeland, John Willy (2009). Severe postprandial hypoglycaemia following duodenal switch. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Hove, Anne Birgitte & Bøhmer, Thomas (2009). Thiamine assay values: influence of anticoagulants and haemoglobin. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 69(4), s. 460–461. doi: 10.1080/00365510902783676. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T.; Bjorkman, Sofia; Søvik, Torgeir Thorson; Engstrom, My; Hanvold, Susanna & Mala, Tom [Vis alle 8 forfattere av denne artikkelen] (2009). Vitamin status after bariatric surgery: a randomized study of gastric bypass and duodenal switch. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. & Bøhmer, Thomas (2008). Low urinary magnesium excretion in morbidly obese women. Clinical Nutrition. ISSN 0261-5614. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Taha, Osama; AASHEIM, ERLEND T.; Bjorkman, Sofia; Kristinsson, Jon Adalsteinn & Engstrom, My [Vis alle 10 forfattere av denne artikkelen] (2008). Laparoscopic gastric bypass vs. laparoscopic duodenal switch in super-obesity - a randomized clinical trial. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Taha, Osama; AASHEIM, ERLEND T.; Bjorkman, Sofia; Kristinsson, Jon Adalsteinn & Engstrom, My [Vis alle 10 forfattere av denne artikkelen] (2008). Laparoskopisk gastrisk bypass vs. laparoskopisk duodenal switch for super-obese pasienter - en randomisert klinisk studie. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Taha, Osama; AASHEIM, ERLEND T.; Bjorkman, Sofia; Kristinsson, Jon Adalsteinn & Engstrom, My [Vis alle 10 forfattere av denne artikkelen] (2008). Laparoscopic gastric bypass vs. laparoscopic duodenal switch in super-obesity - a randomized clinical trial. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Kristinsson, Jon Adalsteinn; Schou, Carl Fredrik; AASHEIM, ERLEND T.; Nesbakken, Arild & Mala, Tom (2008). Gastric bypass: Effect of caseload on perioperative morbidity, length of surgery and postoperative length of stay. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. & Bøhmer, Thomas (2008). Low preoperative vitamin levels in morbidly obese patients: a role of systemic inflammation? Surgery for Obesity and Related Diseases. ISSN 1550-7289. 4, s. 779–780. doi: 10.1016/j.soard.2008.09.002. Fulltekst i vitenarkiv
• Aasheim, ET & Bøhmer, Thomas (2008). Low preoperative vitamin levels in morbidly obese patients: a role of systemic inflammation? Surgery for Obesity and Related Diseases. ISSN 1550-7289. 4(6), s. 779–780. doi: 10.1016/j.soard.2008.09.002. Fulltekst i vitenarkiv
• Aasheim, Erlend T.; Søvik, Torgeir Thorson & Bakke, Espen (2008). Night blindness after duodenal switch. Surgery for Obesity and Related Diseases. ISSN 1550-7289. 4(5), s. 685–686. doi: 10.1016/j.soard.2008.05.001. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. (2008). Wernicke's encephalopathy after bariatric surgery: A systematic review of 76 cases. International Journal of Obesity. ISSN 0307-0565. 32, s. S101–S101. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Kristinsson, Jon Adalsteinn; Schou, Carl Fredrik; AASHEIM, ERLEND T.; Nesbakken, Arild & Mala, Tom (2007). Gastrisk bypass: Postoperativ endring i vekt og komorbiditet. Fulltekst i vitenarkiv
• Søvik, Torgeir Thorson; Schou, Carl Fredrik; Kristinsson, Jon Adalsteinn; AASHEIM, ERLEND T.; Nesbakken, Arild & Mala, Tom (2007). Gastrisk bypass: Effekt av prosedyrevolum på perioperativ morbiditet, operasjonstid og postoperativ liggetid. Fulltekst i vitenarkiv
• AASHEIM, ERLEND T. & Bøhmer, Thomas (2010). Vitamin concentrations in Scandinavian obese subjects undergoing surgical and non-surgical weight loss. Universitetet i Oslo. ISSN 9788280725936. Fulltekst i vitenarkiv

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