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Autophagy
Dysfunctional autophagy is linked to several pathophysiological conditions, including cancer and neurodegenerative disorders. The main focus of the “Simonsen Lab” is to characterize of the molecular mechanisms involved in cargo sequestration and autophagosome biogenesis during non-selective and selective types of autophagy with a long-term goal to identify novel targets for diagnosis or treatment of human disease.
The Simonsen Lab 2023 (form left): Chiara Veroni, Laura Rodriguez de la Ballina, Lauren Sophie Johnson, Anne Gjøen Simonsen, Laura Trachsel Moncho, Patricia Gonzalez-Rodriguez, Arja Arnesen Løchen, Nagham Theres Asp, Muhammad Zahoor, Benan John Mathai, Øyvind Singstad. Not present: Anette Kathinka Dahl, Serhiy Pankiv, Sakshi Singh, Santosh Phuyal. Photo: Ine Eriksen.
About the group
Work in our laboratory is currently focused on identification of novel lipid-binding proteins involved in different types of autophagy and elucidation of their function in autophagy and link to disease. To address these challenges, we use a combination of cell biological, biochemical, imaging, genomic and computational approaches, as well as disease-related model systems.
Research Projects
Our research is funded by
- The University of Oslo
- The Research Council of Norway
- The Norwegian Cancer Society
- H-2020 MSC COFUND and ITN actions
Published Feb. 23, 2011 3:12 PM
- Last modified Sep. 4, 2023 10:03 AM
Contact
Mailing address
P.O.Box 1112 Blindern
0317 Oslo
Visiting address
Domus Medica, Gaustad
Sognsvannsveien 9
0372 Oslo
Group leader
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Hesso Farhan
University of Oslo
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Muhammad Zahoor
University of Oslo
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Detailed list of participants
Scientia Fellows host
This research group is a qualified host of the post doctoral fellowship Scientia Fellows.