The Corthay Group
The Corthay lab investigates the interplay between the immune system and tissue with a main focus on two types of immune cells, namely tumor-specific T cells and macrophages.
About the group
Our research vision is to increase the understanding of how the immune system naturally fights cancer in order to develop novel strategies for cancer immunotherapy, and at the same time pave the ground for testing immune interactions with other tissues. We perform both in vivo and in vitro experiments with experimental mouse models, cell lines and tumor tissue from patients with non-small cell lung cancer (NSCLC). The Corthay group joined the Hybrid Technology Hub in 2019 with the task of developing a chip with components of the immune system in which cell interactions and key processes (such as cell division and death) will be visualized over several days by high-content video-microscopy. Using an in-built perfusion system, the effect of drugs on the interactions will be monitored live minute-by-minute.