Thomas Sæther

Førsteamanuensis - Stem Cell Epigenetics
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Phone +47 22851510
Room 2245
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Visiting address Sognsvannsveien 9 Domus Medica 0372 Oslo
Postal address Postboks 1112 Blindern 0317 Oslo

Academic Interests

My research focus lies at the crossroad between transcription, gene regulation and nutrition. Currently, I am an Associate Professor in the Chromatin research group at the Dept. for Molecular Medicine, where we focus on chromatin regulation in adipose stem cells. We are also studying transcriptional complexes involved in the regulation of de novo lipogenesis in liver.

 

Teaching responsibilities

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Higher education and employment history

  • Associate Professor in the Nuclear Receptor group at Dept. for Nutrition, UiO, from 2015-2018, studying regulation of hepatic de novo lipogenesis.
  • Postdoc in the Nuclear Receptor group at Dept. for Nutrition, UiO and Inst. for Medical biology at UiT, from 2012 to 2015, marine bioprospecting for novel PPAR agonists.
  • Postdoc in the MYB group at IMBV, UiO, from 2008 to 2012, focusing on the transcription factor c-Myb, eukaryotic gene regulation, transcription, chromatin, epigenetics, and post-translational modification, especially SUMOylation.
  • PhD in molecular biosciences, UiO, 2008: Positive and negative modulation of the transactivation potential of the transcription factor c-Myb - novel regulatory mechanisms for a classical proto-oncoprotein. Read more
  • MSc in biochemistry, UiO, 2003:  Metabolism of polyunsaturated fatty acids in rat testis. Read more

Honoraria

  • Throne Holst Foundation of Nutrition Research, Best poster 2016: Anti-diabetic activity from marine lipids: new anti-diabetic drug.
  • Nordic Association for Andrology’s Young Scientist Award, 2001: Effect of dietary fats, insulin and dexamethasone on delta-6-desaturase expression in rat testis.

Collaboration

  • Prof. Trond Vidar Hansen, Dept. of Pharmaceutical Chemistry , UiO: Chemical synthesis of PPAR-activating compounds.
  • Prof. Ingebrigt Sylte, Dept. of Medical Biology, UiT The Arctic University of Norway: 3D in silico docking of PPAR-agonists.
  • Senior Scientist Steinar Paulsen, MabCent - SFI, UiT The Arctic University of Norway: HTS for novel nuclear receptor ligands from marine invertebrates.
  • Prof. Hilde Nebb, Dept. of Nutrition, UiO: Metabolic regulation and life style diseases. 
  • Prof. Dan Voytas, University of Minnesota: Design of zincfinger nucleases for targeted gene editing.
  • Prof. Tom Gonda, University of Queensland: Studies of the transforming potential of the transcription factor c-Myb.
Published Feb. 10, 2014 2:03 PM - Last modified Mar. 22, 2021 8:55 AM