Jørgen Wesche

Professor II - Seksjon for Biokjemi
Bilde av Jørgen Wesche
English version of this page
Brukernavn
Besøksadresse Sognsvannsveien 9 Domus Medica 0372 OSLO
Postadresse Postboks 1112 Blindern 0317 OSLO

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Samarbeid

 

Publikasjoner

  • Fafílek, Bohumil; Bálek, Lukáš; Bosakova, Michaela Kunova; Vařecha, Miroslav; Nita, Alexandru; Gregor, Tomas; Gudernovǎ, Iva; Krenova, Jitka; Ghosh, Somadri; Piskáček, Martin; Jonatova, Lucie; Cernohorsky, Nicole H.; Zieba, Jennifer T.; Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Wesche, Jørgen; Erneux, Christophe; Trántirek, Lukáš; Krakow, Deborah & Krejčí, Pavel (2018). The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases. Science Signaling.  ISSN 1945-0877.  11:eaap8608(548), s 1- 15 . doi: 10.1126/scisignal.aap8608
  • Kostas, Michal Janusz; Haugsten, Ellen Margrethe; Zhen, Yan; Sørensen, Vigdis; Szybowska, Patrycja Maria; Fiorito, Elisa; Lorenz, Susanne; Jones, Nina; De Souza, Gustavo Antonio; Wiedlocha, Antoni & Wesche, Jørgen (2018). Protein Tyrosine Phosphatase Receptor Type G (PTPRG) controls Fibroblast Growth Factor Receptor (FGFR) 1 activity and influences sensitivity to FGFR kinase inhibitors. Molecular & Cellular Proteomics.  ISSN 1535-9476.  17(5), s 850- 870 . doi: 10.1074/mcp.RA117.000538 Vis sammendrag
  • Zhen, Yan; Haugsten, Ellen Margrethe; Singh, Sachin Kumar & Wesche, Jørgen (2018). Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4. Biochemistry.  ISSN 0006-2960.  57(26), s 3807- 3816 . doi: 10.1021/acs.biochem.8b00120 Vis sammendrag
  • Haugsten, Ellen Margrethe; Sørensen, Vigdis; Kunova Bosakova, Michaela; De Souza, Gustavo Antonio; Krejci, Pavel; Wiedlocha, Antoni & Wesche, Jørgen (2016). Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport. Journal of Proteome Research.  ISSN 1535-3893.  15(10), s 3841- 3855 . doi: 10.1021/acs.jproteome.6b00652
  • Haugsten, Ellen Margrethe; Brech, Andreas; Liestøl, Knut; Norman, Jim C. & Wesche, Jørgen (2014). Photoactivation Approaches Reveal a Role for Rab11 in FGFR4 Recycling and Signalling. Traffic : the International Journal of Intracellular Transport.  ISSN 1398-9219.  15(6), s 665- 683 . doi: 10.1111/tra.12168
  • Nadratowska-Wesolowska, Beata; Haugsten, Ellen Margrethe; Zakrzewska, Malgorzata; Jakimowicz, Piotr; Zhen, Yan; Pajdzik, Dorota; Wesche, Jørgen & Wiedlocha, Antoni (2014). RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789. Oncogene.  ISSN 0950-9232.  33(40), s 4823- 4836 . doi: 10.1038/onc.2013.425
  • Oppelt, Angela; Haugsten, Ellen Margrethe; Zech, Tobias; Danielsen, Håvard Emil; Sveen, Anita; Lobert, Viola Helene; Skotheim, Rolf Inge & Wesche, Jørgen (2014). PIKfyve, MTMR3 and their product PtdIns5P regulate cancer cell migration and invasion through activation of Rac1. Biochemical Journal.  ISSN 0264-6021.  461(3), s 383- 390 . doi: 10.1042/BJ20140132
  • Oppelt, Angela; Lobert, Viola Helene; Haglund, Kaisa; Mackey, Ashley M.; Rameh, Lucia E.; Liestøl, Knut; Schink, Kay Oliver; Pedersen, Nina Marie; Wenzel, Eva; Haugsten, Ellen Margrethe; Brech, Andreas; Rusten, Tor Erik; Stenmark, Harald Alfred & Wesche, Jørgen (2013). Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration. EMBO Reports.  ISSN 1469-221X.  14(1), s 57- 64 . doi: 10.1038/embor.2012.183
  • Zakrzewska, Malgorzata; Haugsten, Ellen Margrethe; Nadratowska-Wesolowska, Beata; Oppelt, Angela; Hausott, Barbara; Jin, Yixin; Otlewski, Jacek; Wesche, Jørgen & Wiedlocha, Antoni (2013). ERK-Mediated Phosphorylation of Fibroblast Growth Factor Receptor 1 on Ser(777) Inhibits Signaling. Science Signaling.  ISSN 1945-0877.  6(262) . doi: 10.1126/scisignal.2003087
  • Haugsten, Ellen Margrethe; Zakrzewska, Malgorzata; Brech, Andreas; Pust, Sascha; Olsnes, Sjur; Sandvig, Kirsten & Wesche, Jørgen (2011). Clathrin- and Dynamin-Independent Endocytosis of FGFR3-Implications for Signalling. PLOS ONE.  ISSN 1932-6203.  6(7) . doi: 10.1371/journal.pone.0021708
  • Wesche, Jørgen; Haglund, Kaisa & Haugsten, Ellen Margrethe (2011). Fibroblast growth factors and their receptors in cancer. Biochemical Journal.  ISSN 0264-6021.  437, s 199- 213 . doi: 10.1042/BJ20101603
  • Haglund, Kaisa; Nezis, Jonnis P; Lemus Torres, Dafne; Grabbe, C; Wesche, Jørgen; Liestøl, Knut; Dikic, I; Stenmark, Harald Alfred & Palmer, R. Barton (2010). Cindr Interacts with Anillin to Control Cytokinesis in Drosophila melanogaster. Current Biology.  ISSN 0960-9822.  20(10), s 944- 950 . doi: 10.1016/j.cub.2010.03.068
  • Haugsten, Ellen Margrethe; Wiedlocha, Antoni; Olsnes, Sjur & Wesche, Jørgen (2010). Roles of Fibroblast Growth Factor Receptors in Carcinogenesis. Molecular Cancer Research.  ISSN 1541-7786.  8(11), s 1439- 1452 . doi: 10.1158/1541-7786.MCR-10-0168
  • Lobert, Viola Helene; Brech, Andreas; Pedersen, Nina Marie; Wesche, Jørgen; Oppelt, Angela; Malerød, Lene & Stenmark, Harald (2010). Ubiquitination of alpha 5 beta 1 lntegrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-lntegrin Complexes. Developmental Cell.  ISSN 1534-5807.  19(1), s 148- 159 . doi: 10.1016/j.devcel.2010.06.010
  • Zakrzewska, Malgorzata; Zhen, Yan; Wiedlocha, Antoni; Olsnes, Sjur & Wesche, Jørgen (2009). Size Limitation in Translocation of Fibroblast Growth Factor 1 Fusion Proteins across the Endosomal Membrane. Biochemistry.  ISSN 0006-2960.  48(30), s 7209- 7218 . doi: 10.1021/bi9007353
  • Haugsten, Ellen Margrethe; Malecki, Jedrzej M.; Bjørklund, Sunniva Maria Stordal; Olsnes, Sjur & Wesche, Jørgen (2008). Ubiquitination of fibroblast growth factor receptor 1 is required for its intracellular sorting but not for its endocytosis. Molecular Biology of the Cell.  ISSN 1059-1524.  19, s 3390- 3403 . doi: 10.1091/mbc.E07-12-1219
  • Nilsen, Trine; Rosendal, Ken; Sørensen, Vigdis; Wesche, Jørgen; Olsnes, Sjur & Widocha, Antoni (2007). A nuclear export sequence located on a beta-strand in fibroblast growth factor-1. Journal of Biological Chemistry.  ISSN 0021-9258.  282(36), s 26245- 26256 . doi: 10.1074/jbc.M611234200
  • Sørensen, Vigdis; Wiedlocha, Antoni; Haugsten, Ellen Margrethe; Khnykin, Denis; Wesche, Jørgen & Olsnes, Sjur (2006). Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail. Journal of Cell Science.  ISSN 0021-9533.  119, s 4332- 4341
  • Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Skjerpen, Camilla Skiple; Claus, P & Olsnes, Sjur (2006). FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus. Journal of Biological Chemistry.  ISSN 0021-9258.  281, s 11405- 11412
  • Haugsten, Ellen Margrethe; Sørensen, Vigdis; Olsnes, Sjur; Wesche, Jørgen & Brech, Andreas (2005). Different intracellular trafficking of FGF1 endocytosed by the four specific and homologous FGF receptors. Journal of Cell Science.  ISSN 0021-9533.  118, s 3869- 3881
  • Wesche, Jørgen; Malecki, Jedrzej M.; Wiedlocha, Antoni; Ehsani, Maryam; Nilsen, Trine; Marcinkowska, Ewa & Olsnes, Sjur (2005). Two nuclear localization signals required for transport from the cytosol to the, nucleus of externally added FGF-1 translocated into cells. Biochemistry (Moscow).  ISSN 0006-2979.  44
  • Wiedlocha, Antoni; Nilsen, Trine; Wesche, Jørgen; Sørensen, Vigdis; Malecki, M; Marcinkowska, Ewa & Olsnes, Sjur (2005). Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1. Molecular Biology of the Cell.  ISSN 1059-1524.  (16), s 794- 810
  • Malecki, Jedrzej; Wesche, Jørgen; Skjerpen, Camilla Skiple; Wiedlocha, Antoni & Olsnes, Sjur (2004). Translocation of FGF-1 and FGF-2 across Vesicular Membranes Occurs during G1-Phase by a Common Mechanism. Molecular Biology of the Cell.  ISSN 1059-1524.  15, s 804- 814

Se alle arbeider i Cristin

  • Skjerpen, Camilla Skiple; Olsnes, Sjur & Wesche, Jørgen (2005). Translocation mechanism and cellular interaction partners of FGF-1 and FGF-2.

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Publisert 12. apr. 2019 10:46 - Sist endret 30. sep. 2019 16:03