Oleksandr Frei

Forsker - NORMENT part UiO
Associate Professor - Centre for bioinformatics
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Visiting address Oslo Universitetssykehus HF - Ullevål Avdeling for psykoseforskning Bygg 49 0424 Oslo
Postal address OUS, Postboks 4956 Nydalen 0424 Oslo

I work at NORMENT (Norwegian Centre for Mental Disorders Research) at UiO Faculty of Medicine. We study Genetics of Psychiatric Disorders, identifying rare genetic variants or variation in gene expression in order to uncover hidden heritability of Schizophrenia and other mental disorders.

I have background in mathematics and machine learning. My PhD thesis is "Symmetry and randomizations in combinatorial theory of generalization ability" (Moscow Institute of Physics and Technology, 2013). I also have few years of experience in building industrial software. I worked on Search Engine for Sharepoint (Microsoft, 2010-2013), and on Petrel E&P Software Platform for seismic to simulation reservoir engineering (Schlumberger, 2014-2016).

My hobbies are cycling, skiing, hiking, and more cycling.

Publications

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  • Maximov, Ivan; van der Meer, Dennis; de Lange, Ann-Marie Glasø; Kaufmann, Tobias; Shadrin, Alexey & Frei, Oleksandr [Show all 8 contributors for this article] (2021). YTTRIUM: QC algorithm for the processed diffusion maps in UK Biobank 18608 sample.
  • Smeland, Olav Bjerkehagen; Bahrami, Shahram; Frei, Oleksandr; Shadrin, Alexey A.; Savage, Jeanne E. & Watanabe, Kyoko [Show all 14 contributors for this article] (2018). Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder and intelligence .
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Wang, Yunpeng; Fan, Chun Chieh; Alexey, Shadrin & Li, Wen [Show all 13 contributors for this article] (2017). Increased discovery of risk loci for bipolar disorder by leveraging prior probabilities of true associations using the covariate modulated mixture model (CM3).
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Wang, Yunpeng; Fan, Chun Chieh; Shadrin, Alexey A. & Li, Wen [Show all 13 contributors for this article] (2017). C-Reactive Protein Levels and Schizophrenia Share Genetic Influences.
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Wang, Yunpeng; Dale, Anders & Andreassen, Ole Andreas (2017). Combined Analysis of Large Genetic Samples. New Statistical Approaches Improve Gene Discovery.
  • Smeland, Olav Bjerkehagen; Wang, Yunpeng; Frei, Oleksandr; Li, Wen; Hibar, Derrek & Franke, Barbara [Show all 13 contributors for this article] (2017). Conditional false discovery rate analysis of genome-wide association studies uncovers genetic loci shared between schizophrenia and volumes of hippocampus, putamen and intracranial volume.
  • Smeland, Olav Bjerkehagen; Kauppi, Karolina; Wang, Yunpeng; Frei, Oleksandr; Li, Wen & Hill, David W [Show all 17 contributors for this article] (2016). Schizophrenia and general cognitive function share genetic influences.

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Published June 7, 2016 8:55 AM - Last modified Apr. 5, 2018 5:19 PM

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