Ivar Sjaastad

Bilde av Ivar Sjaastad
English version of this page
Telefon +47 23016797
Brukernavn
Besøksadresse Kirkeveien 166 Bygg 7 0450 Oslo
Postadresse OUS HF Ullevål sykehus Postboks 4956 Nydalen 0424 Oslo

Faglige interesser

Forsker på mekanismer for utvikling av hjertesvikt, med hovedfokus på avbildningsmetoder. Forskningsgruppen gjennomfører både prekliniske og kliniske studier. Mye av forskningen for tiden er fokusert rundt diastolisk dysfunksjon, som også er temaet for KG Jebsen senter for hjerteforskning.

Bakgrunn

  • Professor og avdelingsleder ved Institutt for eksperimentell medisinsk forskning.
  • Leder av KG Jebsen senter for hjerteforskning
  • spesialist i indremedisin og kardiologi, og tok sin doktorgrad ved UiO i 2001.
Emneord: Hjertesvikt, Hjerte kar og lunger, Hjerte

Publikasjoner

  • Gonzalez, Alba; Nome, Cecilie; Bendiksen, Bård Andre; Sjaastad, Ivar; Zhang, Lili; Aleksandersen, Mona; Taubøll, Erik; Aurlien, Dag & Heuser, Kjell (2020). Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy. Epilepsy Research.  ISSN 0920-1211.  161, s 1- 7 . doi: 10.1016/j.eplepsyres.2020.106300 Fulltekst i vitenarkiv.
  • Harbo, Markus Borge; Norden, Einar Sjaastad; Narula, Jagat; Sjaastad, Ivar & Espe, Emil Knut Stenersen (2020). Quantifying left ventricular function in heart failure: What makes a clinically valuable parameter?. Progress in cardiovascular diseases.  ISSN 0033-0620.  s 1- 9 . doi: 10.1016/j.pcad.2020.05.007
  • Mohammadzadeh, Naiyereh; Melleby, Arne Olav; Palmero, Sheryl; Sjaastad, Ivar; Chakravarti, Shukti; Engebretsen, Kristin V Thunheim; Christensen, Geir Arve; Lunde, Ida Gjervold & Tønnessen, Theis (2020). Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload. Cardiology.  ISSN 0008-6312.  145(3), s 187- 198 . doi: 10.1159/000505318
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Addolorata, Pisconti; Høst, Vibeke; Lunde, Marianne; Kristian Hovde, Liland; Sjaastad, Ivar; Svein Olav, Kolset; Christensen, Geir Arve & Mona Elisabeth, Pedersen (2020). Syndecan-4/Mice have smaller muscle fibers, increased Akt/mTOR/S6K1 and notch/HES-1 pathways, and alterations in extracellular matrix components. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X. . doi: 10.3389/fcell.2020.00730
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Pisconti, Addolorata; Høst, Vibeke; Lunde, Marianne; Liland, Kristian Hovde; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2020). Syndecan-4–/– Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components.. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X. . doi: 10.3389/fcell.2020.00730
  • Tazmini, Kiarash; Frisk, Michael; Lewalle, Alexandre; Laasmaa, Martin; Morotti, Stefano; Lipsett, David Bruce; Manfra, Ornella; Skogestad, Jonas; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Edwards, Andrew G.; Grandi, Eleonora; Niederer, Steven A.; Øie, Erik & Louch, William E. (2020). Hypokalemia promotes arrhythmia by distinct mechanisms in atrial and ventricular myocytes. Circulation Research.  ISSN 0009-7330.  126(7), s 889- 906 . doi: 10.1161/CIRCRESAHA.119.315641
  • Barth, Zoltan; Schwartz, Thomas; Flatø, Berit; Aaløkken, Trond Mogens; Koller, Akos; Lund, May-Brith; Sjaastad, Ivar & Sanner, Helga (2019). The association between nailfold capillary density and pulmonary and cardiac involvement in medium-to long-standing juvenile dermatomyositis. Arthritis care & research.  ISSN 2151-464X.  71(4), s 492- 497 . doi: 10.1002/acr.23687 Fulltekst i vitenarkiv.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Eken, Olav Søvik; Sadredini, Mani; Myhre, Peder Langeland; Shen, Xin; Dalhus, Bjørn; Laver, Derek R.; Lunde, Per Kristian; Kurola, Jouni; Lunde, Marianne; Hoff, Jon Erik; Godang, Kristin; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Lehnart, Stephan E.; Edwards, Andrew; Lunde, Ida Gjervold; Omland, Torbjørn; Stokke, Mathis Korseberg; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2019). Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia. Circulation: Arrhythmia and Electrophysiology.  ISSN 1941-3149.  12(4) . doi: 10.1161/CIRCEP.118.007045 Fulltekst i vitenarkiv.
  • Berntsen, Kristin Schjander; Edvardsen, Elisabeth; Hansen, Bjørge Hermann; Flatø, Berit; Sjaastad, Ivar & Sanner, Helga (2019). Cardiorespiratory fitness in long-term juvenile dermatomyositis: A controlled, cross-sectional study of active/inactive disease. Rheumatology.  ISSN 1462-0324.  58(3), s 492- 501 . doi: 10.1093/rheumatology/key342 Fulltekst i vitenarkiv. Vis sammendrag
  • Berntsen, Kristin Schjander; Raastad, Truls; Marstein, Henriette; Kirkhus, Eva Astrid; Merckoll, Else; Cumming, Kristoffer Toldnes; Flatø, Berit; Sjaastad, Ivar & Sanner, Helga (2019). Functional and Structural Adaptations of Skeletal Muscle in Long-Term Juvenile Dermatomyositis; a Controlled Cross-Sectional Study. Arthritis & Rheumatology.  ISSN 2326-5191. . doi: 10.1002/art.41174 Fulltekst i vitenarkiv.
  • Blom, Kjersti Benedicte; Bergo, Kaja Knudsen; Espe, Emil Knut Stenersen; Rosseland, Vigdis; Grøtta, Ole Jørgen; Mjøen, Geir; Åsberg, Anders; Bergan, Stein; Sanner, Helga; Bergersen, Tone Kristin; Bjørnerheim, Reidar; Skauby, Morten Heier; Seljeflot, Ingebjørg; Waldum-Grevbo, Bård; Dahle, Dag Olav; Sjaastad, Ivar & Birkeland, Jon Arne (2019). Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study. Blood Pressure.  ISSN 0803-7051.  s 1- 13 . doi: 10.1080/08037051.2019.1684817 Fulltekst i vitenarkiv.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Zhang, Lili & Sjaastad, Ivar (2019). Regional right ventricular function in rats: a novel magnetic resonance imaging method for measurement of right ventricular strain. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  318(1), s 143- 153 . doi: 10.1152/ajpheart.00357.2019 Fulltekst i vitenarkiv.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Buonarati, Olivia R.; Cataliotti, Alessandro; Hell, Johannes W.; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2019). Cardiomyocyte substructure reverts to an immature phenotype during heart failure. Journal of Physiology.  ISSN 0022-3751.  597(7), s 1833- 1853 . doi: 10.1113/JP277273 Fulltekst i vitenarkiv.
  • Marstein, Henriette; Schwartz, Thomas; Aaløkken, Trond M; Lund, May-Brith; Flatø, Berit; Sjaastad, Ivar & Sanner, Helga (2019). Novel associations between cytokines and pulmonary involvement in juvenile dermatomyositis - a cross-sectional study of long-term disease. Rheumatology.  ISSN 1462-0324.  2019;0 . doi: 10.1093/rheumatology/kez531 Fulltekst i vitenarkiv.
  • Mathiesen, Sabrina Bech; Lunde, Marianne; Aronsen, Jan Magnus; Romaine, Andreas; Kaupang, Anita; Martinsen, Marita; De Souza, Gustavo Antonio; Nyman, Tuula Anneli; Sjaastad, Ivar; Christensen, Geir Arve & Carlson, Cathrine Rein (2019). The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP). Journal of Biological Chemistry.  ISSN 0021-9258.  294(22), s 8717- 8731 . doi: 10.1074/jbc.RA118.006423 Fulltekst i vitenarkiv. Vis sammendrag
  • Mcginley, Gary George; Bendiksen, Bård Andre; Zhang, Lili; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Sjaastad, Ivar & Espe, Emil Knut Stenersen (2019). Accelerated magnetic resonance imaging tissue phase mapping of the rat myocardium using compressed sensing with iterative soft-thresholding. PLOS ONE.  ISSN 1932-6203.  14:e0218874(7), s 1- 17 . doi: 10.1371/journal.pone.0218874 Fulltekst i vitenarkiv.
  • Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Andenæs, Kine; Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Marstein, Henriette; Bandlien, Caroline; Nygård, Ståle; Gorham, Joshua; Sjaastad, Ivar; Chakravarti, Shukti; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2019). The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload. Scientific Reports.  ISSN 2045-2322.  9:9206, s 1- 13 . doi: 10.1038/s41598-019-45651-9 Fulltekst i vitenarkiv.
  • NOMELAND, BIRGIT; Hetlevik, Siri Opsahl; Sanner, Helga; Barth, Zoltan; Schwartz, Thomas; Flatø, Berit; Lilleby, Vibke & Sjaastad, Ivar (2019). Cardiac function is impaired in longstanding juvenile-onset mixed connective tissue disease - a controlled study. Journal of Rheumatology.  ISSN 0315-162X.  46(7), s 739- 747 . doi: 10.3899/jrheum.180526 Fulltekst i vitenarkiv.
  • Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Manfra, Ornella; Longobardi, S; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Husebye, T.; Kolstad, Terje R Selnes; Cataliotti, Alessandro; Christensen, Geir Arve; Sejersted, Ole M; Niederer, Steven A.; Andersen, Geir Øystein; Sjaastad, Ivar & Louch, William Edward (2019). Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression. Cardiovascular Research (CVR).  ISSN 0008-6363.  115(4), s 752- 764 . doi: 10.1093/cvr/cvy257
  • Skogestad, Jonas; Aronsen, Jan Magnus; Tovsrud, Nils; Wanichawan, Pimthanya; Hougen, Karina; Stokke, Mathis Korseberg; Carlson, Cathrine Rein; Sjaastad, Ivar; Sejersted, Ole M & Swift, Fredrik (2019). Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes. Cardiovascular Research (CVR).  ISSN 0008-6363.  116(1), s 78- 90 . doi: 10.1093/cvr/cvz087
  • Skogestad, Jonas; Lines, Glenn; Louch, William Edward; Sejersted, Ole M; Sjaastad, Ivar & Aronsen, Jan Magnus (2019). Evidence for heterogeneous subsarcolemmal Na+ Levels in rat ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  316(5) . doi: 10.1152/ajpheart.00637.2018
  • Sokolova, Marina; Sjaastad, Ivar; Louwe, Maria Cornelia; Alfsnes, Katrine; Aronsen, Jan Magnus; Zhang, Lili; Haugstad, Solveig Bjærum; Bendiksen, Bård Andre; Øgaard, Jonas; Bliksøen, Marte; Lien, Egil; Berge, Rolf Kristian; Aukrust, Pål; Ranheim, Trine & Yndestad, Arne (2019). NLRP3 inflammasome promotes myocardial remodeling during diet-induced obesity. Frontiers in Immunology.  ISSN 1664-3224.  10:1621(JULY), s 1- 13 . doi: 10.3389/fimmu.2019.01621 Fulltekst i vitenarkiv.
  • Udjus, Camilla; Fadila, Cero; Halvorsen, Bente; Behmen, Dina; Carlson, Cathrine Rein; Bendiksen, Bård Andre; Espe, Emil Knut Stenersen; Sjaastad, Ivar; Løberg, Else Marit; Yndestad, Arne; Aukrust, Pål; Christensen, Geir Arve; Skjønsberg, Ole Henning & Larsen, Karl-Otto (2019). Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  316(6), s L999- L1012 . doi: 10.1152/ajplung.00322.2018 Fulltekst i vitenarkiv.
  • Barth, Zoltan; NOMELAND, BIRGIT; Flatø, Berit; Koller, Akos; Sjaastad, Ivar & Sanner, Helga (2018). Assessment of Microvascular Abnormalities by Nailfold Capillaroscopy in Juvenile Dermatomyositis After Medium- to Long-Term Followup. Arthritis care & research.  ISSN 2151-464X.  70(5), s 768- 776 . doi: 10.1002/acr.23338
  • Andenæs, Kine; Lunde, Ida Gjervold; Mohammadzadeh, Naiyereh; Dahl, Christen Peder; Aronsen, Jan Magnus; Strand, Mari Elen; Palmero, Sheryl; Sjaastad, Ivar; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2018). The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling. PLOS ONE.  ISSN 1932-6203.  13(7), s 1- 20 . doi: 10.1371/journal.pone.0201422 Fulltekst i vitenarkiv.
  • Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani; Leren, Ida Skrinde; Edwards, Andrew; Vincent, Kevin P.; Lehnart, Stephan .; Sejersted, Ole M; Sjaastad, Ivar; Haugaa, Kristina & Stokke, Mathis Korseberg (2018). Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation. PLOS ONE.  ISSN 1932-6203.  13:e0207100(11), s 1- 21 . doi: 10.1371/journal.pone.0207100 Fulltekst i vitenarkiv.
  • Kolstad, Terje R Selnes; Brink, Jonas van Den; Macquaide, Niall; Lunde, Per Kristian; Frisk, Michael; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Cataliotti, Alessandro; Sjaastad, Ivar; Sejersted, Ole M; Edwards, Andrew; Lines, Glenn Terje & Louch, William Edward (2018). Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes. eLIFE.  ISSN 2050-084X.  7 . doi: 10.7554/eLife.39427 Fulltekst i vitenarkiv.
  • Melleby, Arne Olav; Romaine, Andreas; Aronsen, Jan Magnus; Veras, Ioanni; Zhang, Lili; Sjaastad, Ivar; Lunde, Ida Gjervold & Christensen, Geir Arve (2018). A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice. Cardiovascular Research (CVR).  ISSN 0008-6363. . doi: 10.1093/cvr/cvy141 Fulltekst i vitenarkiv.
  • Barth, Zoltan; Witzcak, Birgit; Flatø, Berit; Koller, Akos; Sjaastad, Ivar & Sanner, Helga (2017). Microvascular Abnormalities Assessed by Nailfold Capillaroscopy In Juvenile Dermatomyositis After Medium to Long-Term Follow-Up. Arthritis Care and Research.  ISSN 0893-7524. . doi: 10.1002/acr.23338
  • Aronsen, Jan Magnus; Espe, Emil Knut Stenersen; Young-Halvorsen, Kristine Skårdal; Hasic, Almira; Zhang, Lili & Sjaastad, Ivar (2017). Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  312(5), s H932- H942 . doi: 10.1152/ajpheart.00668.2016
  • Berntsen, Kristin Schjander; Tollisen, Anita; Schwartz, Thomas; Kirkhus, Eva; Aaløkken, Trond Mogens; Samersaw-Lund, May Brit; Flatø, Berit; Sjaastad, Ivar & Sanner, Helga (2017). Submaximal exercise capacity in juvenile dermatomyositis after longterm disease: The contribution of muscle, lung, and heart involvement. Journal of Rheumatology.  ISSN 0315-162X.  44(6), s 827- 834 . doi: 10.3899/jrheum.160997
  • Dhondup, Yangchen; Sjaastad, Ivar; Sandanger, Øystein; Aronsen, Jan Magnus; Ahmed, Muhammad Shakil; Attramadal, Håvard; Finsen, Alexandra; Zhang, Lili; Ranheim, Trine; Alfsnes, Katrine; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2017). Toll-like receptor 9 promotes survival in SERCA2a KO heart failure mice. Mediators of Inflammation.  ISSN 0962-9351.  2017:9450439, s 1- 11 . doi: 10.1155/2017/9450439 Fulltekst i vitenarkiv.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Eriksen, Morten; Sejersted, Ole M; Zhang, Lili & Sjaastad, Ivar (2017). Regional dysfunction after myocardial infarction in rats. Circulation Cardiovascular Imaging.  ISSN 1941-9651.  10(9), s e005997 . doi: 10.1161/CIRCIMAGING.116.005997
  • Espe, Emil Knut Stenersen; Young-Halvorsen, Kristine Skårdal; Aronsen, Jan Magnus; Zhang, Lili & Sjaastad, Ivar (2017). A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data. Magnetic Resonance in Medicine.  ISSN 0740-3194.  78(3), s 1199- 1207 . doi: 10.1002/mrm.26486
  • Gattoni, Sara; Røe, Åsmund Treu; Aronsen, Jan Magnus; Sjaastad, Ivar; Louch, William Edward; Smith, Nicolas P. & Niederer, Steven A. (2017). Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding. Journal of Physiology.  ISSN 0022-3751.  595(12), s 3867- 3889 . doi: 10.1113/JP273879
  • Johansen, Ida Beitnes; Sandblom, Erik; Skov, Peter V.; Gräns, Albin; Ekström, Andreas; Lunde, Ida Gjervold; Vindas, Marco Antonio; Zhang, Lili; Höglund, Erik; Frisk, Michael; Sjaastad, Ivar; Nilsson, Göran Erik & Øverli, Øyvind (2017). Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids. Journal of Experimental Biology.  ISSN 0022-0949.  220(14), s 2545- 2553 . doi: 10.1242/jeb.135046 Fulltekst i vitenarkiv.
  • Landfors, Miriam; Johansen, Jostein; Aronsen, Jan Magnus; Vågbø, Cathrine Broberg; Doré, Louis C.; He, Chuan; Sjaastad, Ivar; Sætrom, Pål; Fedorcsák, Péter; Dahl, John Arne; Aanes, Håvard; Fusser, Markus & Klungland, Arne (2017). Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation. Cell Discovery.  ISSN 2056-5968.  3 . doi: 10.1038/celldisc.2017.13 Fulltekst i vitenarkiv.
  • MANNER, INGJERD W; Waldum-Grevbo, Bård Endre; NOMELAND, BIRGIT; Bækken, Morten; Øktedalen, Olav; Os, Ingrid; Schwartz, Thomas & Sjaastad, Ivar (2017). Immune markers, diurnal blood pressure profile and cardiac function in virologically suppressed HIV-infected patients. Blood Pressure.  ISSN 0803-7051.  26(6), s 332- 340 . doi: 10.1080/08037051.2017.1346459
  • Meier, Silja; Andressen, Kjetil Wessel; Aronsen, Jan Magnus; Sjaastad, Ivar; Hougen, Karina; Skomedal, Tor; Osnes, Jan-Bjørn; Qvigstad, Eirik; Levy, Finn Olav & Moltzau, Lise Roman (2017). PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts. European Journal of Pharmacology.  ISSN 0014-2999.  812, s 174- 183 . doi: 10.1016/j.ejphar.2017.07.014
  • Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward; Iversen, Per Ole; Østlie, Ingunn; Klungland, Arne; Christensen, Geir Arve; Sjaastad, Ivar; Sætrom, Pål; Yndestad, Arne; Aukrust, Pål; Bjørås, Magnar & Finsen, Alexandra (2017). NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports.  ISSN 2211-1247.  18, s 82- 92 . doi: 10.1016/j.celrep.2016.12.009 Fulltekst i vitenarkiv.
  • Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune Forstrøm; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Sjaastad, Ivar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2017). Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis. Circulation: Heart Failure.  ISSN 1941-3289.  10(2) . doi: 10.1161/CIRCHEARTFAILURE.116.003675
  • Romaine, Andreas; Sørensen, Ida Wiig; Zeltz, Cedric; Lu, Ning; Erusappan, Pugazendhi Murugan; Melleby, Arne Olav; Zhang, Lili; Bendiksen, Bård Andre; Robinson, EL; Aronsen, Jan Magnus; Herum, Kate Louise Møller; Danielsen, Håvard Emil; Sjaastad, Ivar; Christensen, Geir Arve & Gullberg, Donald (2017). Overexpression of integrin α11 induces cardiac fibrosis in mice. Acta Physiologica Scandinavica.  ISSN 0001-6772.  222:e13025(2), s 1- 17 . doi: 10.1111/apha.12932
  • Røe, Åsmund Treu; Aronsen, Jan Magnus; Young-Halvorsen, Kristine Skårdal; Hamdani, Nazha; Linke, Wolfgang A.; Danielsen, Håvard Emil; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2017). Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy. Cardiovascular Research (CVR).  ISSN 0008-6363.  113(10), s 1161- 1172 . doi: 10.1093/cvr/cvx087
  • Røe, Åsmund Treu; Sjaastad, Ivar & Louch, William Edward (2017). Hjertesvikt med bevart ejeksjonsfraksjon [Heart failure with preserved ejection fraction]. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  137(18), s 1- 8 . doi: 10.4045/tidsskr.16.1068
  • Thienpont, Bernard; Aronsen, Jan Magnus; Robinson, Emma Louise; Okkenhaug, Hanneke; Loche, Elena; Ferrini, Arianna; Brien, Patrick; Alkass, Kanar; Tomasso, Antonio; Agrawal, Asmita; Bergmann, Olaf; Sjaastad, Ivar; Wolf, Reik & Roderick, Hywel Llewelyn (2017). The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy. Journal of Clinical Investigation.  ISSN 0021-9738.  127(1), s 335- 348 . doi: 10.1172/JCI88353
  • Aronsen, Jan Magnus; Louch, William Edward & Sjaastad, Ivar (2016). Cardiomyocyte Ca2+ dynamics: Clinical perspectives. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  50(2), s 65- 77 . doi: 10.3109/14017431.2015.1136079
  • Barth, Zoltan; NOMELAND, BIRGIT; Schwartz, Thomas; Gjesdal, Knut; Flatø, Berit; Koller, Akos; Sanner, Helga & Sjaastad, Ivar (2016). In juvenile dermatomyositis, heart rate variability is reduced, and associated with both cardiac dysfunction and markers of inflammation: a cross-sectional study median 13.5 years after symptom onset. Rheumatology.  ISSN 1462-0324.  55(3), s 535- 543 . doi: 10.1093/rheumatology/kev376 Vis sammendrag
  • Dhondup, Yangchen; Ueland, Thor; Dahl, Christen Peder; Askevold, Erik Tandberg; Sandanger, Øystein; Fiane, Arnt E; Ohm, Ingrid Kristine; Sjaastad, Ivar; Finsen, Alexandra; Wæhre, Anne; Gullestad, Lars; Aukrust, Pål; Yndestad, Arne & Vinge, Leif Erik (2016). Low circulating levels of mitochondrial and high levels of nuclear DNA predict mortality in chronic heart failure. Journal of Cardiac Failure.  ISSN 1071-9164.  22(10), s 823- 828 . doi: 10.1016/j.cardfail.2016.06.013 Vis sammendrag
  • Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Sejersted, Ole M; Christensen, Geir Arve; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research (CVR).  ISSN 0008-6363. . doi: 10.1093/cw111
  • Hafver, Tandekile Lubelwana; Hodne, Kjetil; Wanichawan, Pimthanya; Aronsen, Jan Magnus; Dalhus, Bjørn; Lunde, Per Kristian; Lunde, Marianne; Martinsen, Marita; Enger, Ulla Helene; Fuller, William; Sjaastad, Ivar; Louch, William Edward; Sejersted, Ole M & Carlson, Cathrine Rein (2016). Protein phosphatase 1c associated with the cardiac sodium calcium exchanger 1 regulates its activity by dephosphorylating Serine 68-phosphorylated phospholemman. Journal of Biological Chemistry.  ISSN 0021-9258.  291(9), s 4561- 4579 . doi: 10.1074/jbc.M115.677898 Vis sammendrag
  • Hortemo, Kristin Halvorsen; Lunde, Per Kristian; Anonsen, Jan Haug; Kvaløy, Heidi; Munkvik, Morten; Rehn, Tommy Aune; Sjaastad, Ivar; Lunde, Ida Gjervold; Aronsen, Jan Magnus & Sejersted, Ole M (2016). Exercise training increases protein O-GlcNAcylation in rat skeletal muscle. Physiological Reports.  ISSN 2051-817X.  4(18), s e12896 . doi: 10.14814/phy2.12896 Fulltekst i vitenarkiv.
  • Logantha, Sunil Jit R.; Stokke, Mathis Korseberg; Atkinson, Andrew J.; Kharche, Sanjay R.; Parveen, Sajida; Saeed, Yawer; Sjaastad, Ivar; Sejersted, Ole M & Dobrzynski, Halina (2016). Ca2+ -clock-dependent pacemaking in the sinus node is impaired in mice with a cardiac specific reduction in SERCA2 abundance. Frontiers in Physiology.  ISSN 1664-042X.  7:197 . doi: 10.3389/fphys.2016.00197
  • Manotheepan, Ravinea; Danielsen, Tore Kristian; Sadredini, Mani; Anderson, Mark E.; Carlson, Cathrine Rein; Lehnart, Stefan; Sjaastad, Ivar & Stokke, Mathis Korseberg (2016). Exercise training prevents ventricular tachycardia in CPVT1 due to reduced CaMKII-dependent arrhythmogenic Ca2+ release. Cardiovascular Research (CVR).  ISSN 0008-6363.  111(3), s 295- 306 . doi: 10.1093/cvr/cvw095
  • Melleby, Arne Olav; Strand, Mari Elen; Romaine, Andreas; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Arnt E; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparan sulfate proteoglycan glypican-6 is upregulated in the failing heart, and regulates cardiomyocyte growth through ERK1/2 Signaling. PLOS ONE.  ISSN 1932-6203.  11(10) . doi: 10.1371/journal.pone.0165079
  • Sadredini, Mani; Danielsen, Tore Kristian; Aronsen, Jan Magnus; Manotheepan, Ravinea; Hougen, Karina; Sjaastad, Ivar & Stokke, Mathis Korseberg (2016). Beta-adrenoceptor stimulation reveals Ca2+ waves and sarcoplasmic reticulum Ca2+ depletion in left ventricular cardiomyocytes from post-infarction rats with and without heart failure. PLOS ONE.  ISSN 1932-6203.  11(4) . doi: 10.1371/journal.pone.0153887
  • Schwartz, Thomas; Diederichsen, Louise Pyndt; Lundberg, Ingrid E.; Sjaastad, Ivar & Sanner, Helga (2016). Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies. RMD Open.  ISSN 2056-5933.  2:e000291(2), s 1- 11 . doi: 10.1136/rmdopen-2016-000291
  • Young-Halvorsen, Kristine Skårdal; Espe, Emil Knut Stenersen; Zhang, Lili; Aronsen, Jan Magnus & Sjaastad, Ivar (2016). Three-directional evaluation of mitral flow in the rat heart by phase-contrast cardiovascular magnetic resonance. PLOS ONE.  ISSN 1932-6203.  11(3) . doi: 10.1371/journal.pone.0150536 Fulltekst i vitenarkiv.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Lewalle, Alexandre; Louch, William Edward; Hougen, Karina; Stokke, Mathis Korseberg; Swift, Fredrik; Niederer, Steven; Smith, Nic P.; Sejersted, Ole M & Sjaastad, Ivar (2015). Hypokalaemia induces Ca2+ overload and Ca2+ waves in ventricular myocytes by reducing Na+ ,K+-ATPase α2 activity. Journal of Physiology.  ISSN 0022-3751.  593(6), s 1509- 1521 . doi: 10.1113/jphysiol.2014.279893
  • Bolstad, Ingeborg; Andreassen, Ole Andreas; Groote, Inge Rasmus; SERVER, ANDRES; Sjaastad, Ivar; Kapur, S & Jensen, Jimmy Kristian (2015). Effects of haloperidol and aripiprazole on the human mesolimbic motivational system: A pharmacological fMRI study. European Neuropsychopharmacology.  ISSN 0924-977X.  25(12), s 2252- 2261 . doi: 10.1016/j.euroneuro.2015.09.016 Vis sammendrag
  • Dhondup, Yangchen; Sjaastad, Ivar; Scott, Helge; Sandanger, Øystein; Zhang, Lili; Haugstad, Solveig Bjærum; Aronsen, Jan Magnus; Ranheim, Trine; Holmen, Sigve; Alfsnes, Katrine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Gullestad, Lars; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2015). Sustained toll-like receptor 9 activation promotes systemic and cardiac inflammation, and aggravates diastolic heart failure in SERCA2a KO Mice. PLOS ONE.  ISSN 1932-6203.  10:e0139715(10) . doi: 10.1371/journal.pone.0139715 Fulltekst i vitenarkiv.
  • Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Eriksen, Guro Søe; Zhang, Lili; Smiseth, Otto A.; Edvardsen, Thor; Sjaastad, Ivar & Eriksen, Morten (2015). Assessment of regional myocardial work in rats. Circulation Cardiovascular Imaging.  ISSN 1941-9651.  8 . doi: 10.1161/CIRCIMAGING.114.002695

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  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Pisconti, Addolorate; Lunde, Marianne; Liland, Kristian Hovde; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2019). Extracellular Matrix remodeling and multiple signaling pathways are regulated by syndecan-4 during myogenesis.
  • Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Liland, Kristian Hovde; Stang, Espen; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2017). Syndecan-4 is a skeletal muscle regenerator and is important for normal skeletal muscle fibre development..
  • Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani; Leren, I.S.; Edwards, Andrew; Vincent, K.; Lehnart, Stefan; Sejersted, Ole M; Sjaastad, Ivar; Haugaa, Kristina & Stokke, Mathis Korseberg (2016). Mechanisms underlying the frequency-dependence of triggered arrhythmias in catecholaminergic polymorphic ventricular tachycardia type 1.
  • Witzcak, Birgit; Schwartz, Thomas; Barth, Zoltan; Lund, M B; Sjaastad, Ivar & Sanner, Helga (2016). Cardiac dysfunction and pulmonary involvement are not associated in juvenile dermatomyositis.
  • Albert, Ingrid; Skogestad, Jonas; Carlson, Cathrine Rein; Lunde, Marianne; Marshall, Serena; Lunde, Per Kristian; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). Development of PDE3A-SERCA2 disruptor agents for SERCA2 activation..
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B; Albert, Ingrid; Marshall, Serena; Børstad, Mira Halvorsen; Lunde, Per Kristian; Morth, Jens Preben; Tasken, Kjetil; Carlson, Cathrine Rein & Sjaastad, Ivar (2016). Physical coupling of PDE3A regulates SERCA2 activity in cardiomyocytes.
  • Bendiksen, Bård Andre; Zhang, Lili; Espe, Emil Knut Stenersen; Schneider, Jurgen E. & Sjaastad, Ivar (2016). Cardiac diffusion tensor imaging of the rodent heart utilizing an optimized gradient configuration with multiple encoding strengths.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Dispersion of ryanodine receptor clusters disrupts calcium sparks in failing cardiomyocyte.
  • Kolstad, Terje R Selnes; Macquaide, Niall; Hake, Johan; Aronsen, Jan Magnus; Frisk, Michael; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Super-resolution imaging reveals dispersion of ryanodine receptor clusters during heart failure.
  • Krohn-Hansen, Dag; Zhang, Lili; Haaskjold, Erlend; Nicolaissen, Bjørn; Meling, Torstein Ragnar & Sjaastad, Ivar (2016). A less invasive surgical approach to the superior part of the orbit.
  • Li, Jia; Frisk, Michael; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M & Louch, William Edward (2016). Regional activation of the Frank-Starling mechanism within the cardiomyocyte.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
  • Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2016). BIN1 triggers t-tubule development in cardiomyocytes.
  • Manotheepan, Ravinea; Danielsen, Tore Kristian; Saberniak, Jorg; Sadredini, Mani; Anderson, Mark e.; Carlson, Cathrine Rein; Edvardsen, Thor; Lehnart, Stefan; Sjaastad, Ivar; Haugaa, Kristina & Stokke, Mathis Korseberg (2016). Exercise training as anti-arrhythmic therapy in cathecholaminergic polymorphic ventricular tachycardia type 1.
  • Marshall, Serena; Børstad, Mira Halvorsen; Skogestad, Jonas; Albert, Ingrid; Lothe, Gustav B; Espe, Emil Knut Stenersen; Zhang, Lili; Louch, William Edward; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). SERCA2 activation is beneficial in chronic heart disease.
  • Marstein, Henriette; Lunde, Per Kristian; Aronsen, Jan Magnus & Sjaastad, Ivar (2016). Inhibition of Alkbh7 regulates cardiac metabolism.
  • McGinley, Gary George; Bendiksen, Bård Andre; Zhang, Lili; Sjaastad, Ivar & Espe, Emil Knut Stenersen (2016). Accelerated myocardial velocity and strain estimation with phase-contrast magnetic resonance imaging using compressed sensing with adaptive thresholding.
  • Melleby, Arne Olav; Strand, Mari Elen; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Andrew; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). Glypican-6 is upregulated in heart failure and mediates cardiomyocyte growth through ERK1/2 signaling.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to cardiac dysfunction in response to pressure overload.
  • Mohammadzadeh, Naiyereh; Engebretsen, Kristin; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to ventricular dilatation, attenuated hypertrophy and contractile dysfunction in response to pressure overload.
  • Norden, Einar Sjaastad; Bergo, Kaja Knudsen; Zhang, Lili; Aronsen, Jan Magnus; Hasic, Almira; Hussain, I.; Sjaastad, Ivar & Cataliotti, Alessandro (2016). Anti-hypertrophic effects of LCZ696 in chronic cardiac pressure overload.
  • Romaine, Andreas; Sørensen, Ida Wiig; Melleby, Arne Olav; Zeltz, Cedric; Zhang, Lili; Bendiksen, Bård Andre; Lu, Neha; Herum, Kate Louise Møller; Danielsen, D.; Sjaastad, Ivar; Gullberg, Donald & Christensen, Geir Arve (2016). Overexpression of integrin a11 induces cardiac hypertrophy and fibrosis.
  • Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five; Aakhus, Svend; Lunde, Ida Gjervold; Almaas, Vibeke; Gullestad, Lars; Sjaastad, Ivar; Tønnessen, Theis; Sejersted, Ole M; Norseng, Per Andreas; Christensen, Geir Arve & Louch, William Edward (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
  • Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts diastolic Calcium homeostasis of the cardiomyocyte.
  • Sadredini, Mani; Manotheepan, Ravinea; Danielsen, Tore Kristian; Lehnart, Stefan; Sjaastad, Ivar & Stokke, Mathis Korseberg (2016). Epac2 inhibition reduces arrhythmogenic Ca2+ wave frequently in cardiomyocytes from mice With catecholaminergic polymorphic ventricular tachcardia type 1.
  • Skogestad, Jonas; Albert, Ingrid; Marshall, Serena; Børstad, Mira Halvorsen; Lothe, Gustav B; Sejersted, Ole M; Sjaastad, Ivar & Aronsen, Jan Magnus (2016). Phosphodiesterase 2 regulates Na+/K+-ATPase activity in adult cardiomyocytes.
  • Skårdal, Kristine; Espe, Emil Knut Stenersen; Bendiksen, Bård Andre; Aronsen, Jan Magnus; Zhang, Lili & Sjaastad, Ivar (2016). Parametrizing active and passive diastolic function non-invasively using phase contrast MRI.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazaukaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazauskaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
  • Tazmini, Kiarash; Frisk, Michael; Lipsett, David Bruce; Aronsen, Jan Magnus; Sjaastad, Ivar; Øie, Erik & Louch, William Edward (2016). Pro-arrhythmic consequences of hypokalemia in atrial cardiomyocytes.
  • Barth, Zoltan; Witzcak, Birgit; Schwartz, Thomas; Gjesdal, Knut; Flatø, Berit; Koller, A'kos; Sanner, Helga & Sjaastad, Ivar (2015). Heart rate variability is related to inflammation and cardiac function in juvenile dermatomyositis.
  • Barth, Zoltan; Witzcak, Birgit; Schwartz, Thomas; Gjesdal, Knut; Flatø, Berit; Koller, A'kos; Sjaastad, Ivar & Sanner, Helga (2015). Heart rate variability is related to inflammation and cardiac function in juvenile dermatomyositis.
  • Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani Nikoo; Gaur, Namit; Leren, IS; Edwards, Andrew; Sejersted, Ole M; Lehnart, Stefan; Sjaastad, Ivar; Haugaa, Kristina & Stokke, Mathis Korseberg (2015). Mechanisms for the frequency-dependence of triggered activity in catecholaminergic polymorphic ventricular tachycardia type 1.
  • Albert, Ingrid; Børstad, Mira Halvorsen; Carlson, Cathrine Rein; Calejo, Anna; Skogestad, Jonas; Lunde, Marianne; Lunde, Per Kristian; Tasken, Kjetil; Sjaastad, Ivar & Aronsen, Jan Magnus (2015). Development of SERCA2 activating agents.
  • Andenæs, Kine; Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Strand, Mari Elen; Marstein, Henriette; Dahl, Christen Peder; Sjaastad, Ivar; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2015). The extracellular matrix proteoglycan fibromodulin is up-regulated in experimental and clinical heart failure, and might be involved in regulation of myocardial fibrosis by interacting with TGF-B.
  • Aronsen, Jan Magnus; Skogestad, Jonas; Hougen, Karina; Lunde, Marianne; Lothe, Gustav B; Albert, Ingrid; Marshall, Serena; Lunde, Per Kristian; Morth, Jens Preben; Tasken, Kjetil; Carlson, Cathrine Rein & Sjaastad, Ivar (2015). Physical coupling between SERCA2 and PDE3A regulates SERCA2 activity in cardiomyocytes.
  • Børstad, Mira Halvorsen; Albert, Ingrid; Lunde, Marianne; Carlson, Cathrine Rein; Sjaastad, Ivar & Aronsen, Jan Magnus (2015). Molecular mechanisms for PDE3A mediated inhibition of SERCA2 activity.
  • Cero, Fadila; Larsen, Karl-Otto; Hillestad, Vigdis; Olsen, Maria Belland; Udjus, Camilla; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Løberg, Else Marit; Christensen, Geir Arve & Skjønsberg, Ole Henning (2015). The inflammasome adaptor ASC mediates pulmonary artery remodelling.

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Publisert 13. apr. 2011 11:44 - Sist endret 17. sep. 2020 10:14