Johny Steinar Kongerud

• Klepaker, Geir; Henneberger, Paul Keefer; Torén, Kjell; Brunborg, Cathrine; Kongerud, Johny & Fell, Anne Kristin M. (2022). Association of respiratory symptoms with body mass index and occupational exposure comparing sexes and subjects with and without asthma: follow-up of a Norwegian population study (the Telemark study). BMJ Open Respiratory Research. ISSN 2052-4439. 9(1), s. 1–10. doi: 10.1136/bmjresp-2021-001186. Vis sammendrag

  Background: Occupational exposure and increased body mass index (BMI) are associated with respiratory symptoms. This study investigated whether the association of a respiratory burden score with changes in BMI as well as changes in occupational exposure to vapours, gas, dust and fumes (VGDF) varied in subjects with and without asthma and in both sexes over a 5-year period. Methods: In a 5-year follow-up of a population-based study, 6350 subjects completed a postal questionnaire in 2013 and 2018. A respiratory burden score based on self-reported respiratory symptoms, BMI and frequency of occupational exposure to VGDF were calculated at both times. The association between change in respiratory burden score and change in BMI or VGDF exposure was assessed using stratified regression models. Results: Changes in respiratory burden score and BMI were associated with a β-coefficient of 0.05 (95% CI 0.04 to 0.07). This association did not vary significantly by sex, with 0.05 (0.03 to 0.07) for women and 0.06 (0.04 to 0.09) for men. The association was stronger among those with asthma (0.12; 0.06 to 0.18) compared with those without asthma (0.05; 0.03 to 0.06) (p=0.011). The association of change in respiratory burden score with change in VGDF exposure gave a β-coefficient of 0.15 (0.05 to 0.19). This association was somewhat greater for men versus women, with coefficients of 0.18 (0.12 to 0.24) and 0.13 (0.07 to 0.19), respectively (p=0.064). The estimate was similar among subjects with asthma (0.18; -0.02 to 0.38) and those without asthma (0.15; 0.11 to 0.19). Conclusions: Increased BMI and exposure to VGDF were associated with increased respiratory burden scores. The change due to increased BMI was not affected by sex, but subjects with asthma had a significantly larger change than those without. Increased frequency of VGDF exposure was associated with increased respiratory burden score but without statistically significant differences with respect to sex or asthma status.

• Myrdal, Ole Henrik; Aaløkken, Trond Mogens; Diep, Phoi Phoi; Ruud, Ellen; Brinch, Lorentz & Fosså, Kristian [Vis alle 10 forfattere av denne artikkelen] (2021). Late-Onset, Noninfectious Pulmonary Complications following Allogeneic Hematopoietic Stem Cell Transplantation: A Nationwide Cohort Study of Long-Term Survivors. Respiration. ISSN 0025-7931. s. 1–9. doi: 10.1159/000520824. Fulltekst i vitenarkiv
• Klepaker, Geir; Henneberger, Paul Keefer; Hertel, Jens Kristoffer; Holla, Øystein Lunde; Kongerud, Johny & Fell, Anne Kristin Møller (2021). Influence of asthma and obesity on respiratory symptoms, work ability and lung function: findings from a cross-sectional Norwegian population study. BMJ Open Respiratory Research. ISSN 2052-4439. doi: 10.1136/bmjresp-2021-000932. Fulltekst i vitenarkiv Vis sammendrag

  Background: Although asthma and obesity are each associated with adverse respiratory outcomes, a possible interaction between them is less studied. This study assessed the extent to which asthma and overweight/obese status were independently associated with respiratory symptoms, lung function, Work Ability Score (WAS) and sick leave; and whether there was an interaction between asthma and body mass index (BMI) ≥25 kg/m2 regarding these outcomes. Methods: In a cross-sectional study, 626 participants with physician-diagnosed asthma and 691 without asthma were examined. All participants completed a questionnaire and performed spirometry. The association of outcome variables with asthma and BMI category were assessed using regression models adjusted for age, sex, smoking status and education. Results: Asthma was associated with reduced WAS (OR=1.9 (95% CI 1.4 to 2.5)), increased sick leave in the last 12 months (OR=1.4 (95% CI 1.1 to 1.8)) and increased symptom score (OR=7.3 (95% CI 5.5 to 9.7)). Obesity was associated with an increased symptom score (OR=1.7 (95% CI 1.2 to 2.4)). Asthma was associated with reduced prebronchodilator and postbronchodilator forced expiratory volume in 1 s (FEV1) (β=-6.6 (95% CI -8.2 to -5.1) and -5.2 (95% CI -6.7 to -3.4), respectively) and prebronchodilator forced vital capacity (FVC) (β=-2.3 (95% CI -3.6 to -0.96)). Obesity was associated with reduced prebronchodilator and postbronchodilator FEV1 (β=-2.9 (95% CI -5.1 to -0.7) and -2.8 (95% CI -4.9 to -0.7), respectively) and FVC (-5.2 (95% CI -7.0 to -3.4) and -4.2 (95% CI -6.1 to -2.3), respectively). The only significant interaction was between asthma and overweight status for prebronchodilator FVC (β=-3.6 (95% CI -6.6 to -0.6)). Conclusions: Asthma and obesity had independent associations with increased symptom scores, reduced prebronchodilator and postbronchodilator FEV1 and reduced prebronchodilator FVC. Reduced WAS and higher odds of sick leave in the last 12 months were associated with asthma, but not with increased BMI. Besides a possible association with reduced FVC, we found no interactions between asthma and increased BMI.

• Ulvestad, Mariann; Godang, Kristin; Durheim, Michael; Kongerud, Johny S.; Lund, May-Brith & Bollerslev, Jens [Vis alle 7 forfattere av denne artikkelen] (2021). Effect of high-intensity training on bone health and body composition in lung transplant recipients: A secondary analysis of a randomized controlled trial. Clinical Transplantation. ISSN 0902-0063. s. 1–9. doi: 10.1111/ctr.14375. Fulltekst i vitenarkiv
• Sikkeland, Liv Ingunn Bjoner; Durheim, Michael Thomas; Riste, Tonje Bøyum; Kongerud, Johny; Alexis, Neil E. & Holm, Are Martin (2020). Relation of sputum neutrophilia to the development of chronic lung allograft dysfunction after lung transplantation. Clinical Transplantation. ISSN 0902-0063. doi: 10.1111/ctr.14188.
• Sikkeland, Liv Ingunn Bjoner; Qiao, Shuo Wang; Ueland, Thor; Myrdal, Ole Henrik; Wyrozemski, Lukasz Adam & Aukrust, Pål [Vis alle 12 forfattere av denne artikkelen] (2020). Lung CD4+ T cells in patients with lung fibrosis produce pro-fibrotic IL-13 together with IFNγ. European Respiratory Journal. ISSN 0903-1936. 57:2000983(3), s. 1–4. doi: 10.1183/13993003.00983-2020. Fulltekst i vitenarkiv
• Myrdal, Ole Henrik; Diep, Phoi Phoi; Ruud, Ellen; Brinch, Lorentz; Massey, Richard J & Edvardsen, Elisabeth [Vis alle 9 forfattere av denne artikkelen] (2020). Determinants of cardiorespiratory fitness in very long-term survivors of allogeneic hematopoietic stem cell transplantation: a national cohort study. Supportive Care in Cancer. ISSN 0941-4355. doi: 10.1007/s00520-020-05644-1. Fulltekst i vitenarkiv Vis sammendrag

  Purpose: Survivors of allogeneic hematopoietic stem cell transplantation (allo-HSCT) are at risk for cardiopulmonary adverse events. Data on long-term effects on cardiorespiratory fitness are limited. To address the gap in knowledge, we aimed to determine peak oxygen uptake (V̇O2peak) and identify associations between cardiorespiratory fitness and clinical characteristics, self-reported physical activity, cardiac, and pulmonary function. Methods: In a nationwide, single-center cross-sectional study, 90 survivors [aged median (range) 35 (17–54) years, 56% females] were examined, 17 (6–26) years after allo-HSCT. Myeloablative conditioning comprised busulfan/cyclophosphamide or cyclophosphamide only. Methods included pulmonary function tests, echocardiography, and cardiopulmonary exercise test. Results: Chronic graft-versus-host disease (cGVHD) was found in 31% of the subjects, of whom 40% had bronchiolitis obliterans syndrome (BOS). Seventy-one percent of the survivors did not meet WHO recommendations for physical activity and 42% were overweight. Reduced gas diffusion (DLCO) and systolic ventricular dysfunction (LVEF) were found in 44% and 31%, respectively. For the group, mean (95% CI), V̇O2peak was 36.4 (34.7–38.0) mL/min/kg [89 (85–93)% of predicted]. V̇O2peak was low at 43%. Cardiopulmonary factors and deconditioning were equally common limitations for exercise. In a multiple linear regression model, low V̇O2peak was associated with low DLCO, low LVEF, BOS, overweight, and inactivity. Conclusion: Half of the survivors had reduced cardiorespiratory fitness median 17 years after allo-HSCT. Cardiopulmonary factors and deconditioning were equally common limitations to exercise. We encourage long-term cardiopulmonary monitoring of allo-HSCT survivors and targeted advice on modifiable lifestyle factors.

• Ulvestad, Mariann; Durheim, Michael; Kongerud, Johny; Hansen, Bjørge Herman; Samersaw-Lund, May Brit & Edvardsen, Elisabeth (2020). Cardiorespiratory Fitness and Physical Activity following Lung Transplantation: A National Cohort Study. Respiration. ISSN 0025-7931. 99(4), s. 316–324. doi: 10.1159/000506883. Fulltekst i vitenarkiv
• Ulvestad, Mariann; Durheim, Michael; Kongerud, Johny; Samersaw-Lund, May Brit & Edvardsen, Elisabeth (2020). Effect of high-intensity training on peak oxygen uptake and muscular strength after lung transplantation: A randomized controlled trial. The Journal of Heart and Lung Transplantation. ISSN 1053-2498. s. 1–9. doi: 10.1016/j.healun.2020.06.006. Fulltekst i vitenarkiv
• Holm, Are Martin; Andreassen, Siw Lillevik; Christensen, Vivi Lycke; Kongerud, Johny; Almås, Øystein & Auråen, Henrik [Vis alle 10 forfattere av denne artikkelen] (2020). Hypogammaglobulinemia and risk of exacerbation and mortality in patients with COPD. The International Journal of Chronic Obstructive Pulmonary Disease. ISSN 1176-9106. 15, s. 799–807. doi: 10.2147/COPD.S236656. Fulltekst i vitenarkiv
• Abrahamsen, Regine; Gundersen, Gølin Finkenhagen; Svendsen, Martin Veel; Klepaker, Geir; Kongerud, Johny & Fell, Anne Kristin Møller (2020). Possible Risk Factors for Poor Asthma Control Assessed in a Cross-Sectional Population-Based Study From Telemark, Norway. PLOS ONE. ISSN 1932-6203. 15(5). doi: 10.1371/journal.pone.0232621. Fulltekst i vitenarkiv
• Müller De Bortoli, Marit; Fell, Anne Kristin Møller; Svendsen, Martin Veel; Henneberger, Paul K; Kongerud, Johny & Oellingrath, Inger Margaret (2020). Lifestyle, sick leave and work ability among Norwegian employees with asthma?A population-based cross-sectional survey conducted in Telemark County, Norway. PLOS ONE. ISSN 1932-6203. doi: 10.1371/journal.pone.0231710. Fulltekst i vitenarkiv Vis sammendrag

  Objective To investigate whether physician-diagnosed asthma modifies the associations between multiple lifestyle factors, sick leave and work ability in a general working population. Methods A cross-sectional study was conducted in Telemark County, Norway, in 2013. A sample of 16 099 respondents completed a self-administered questionnaire. We obtained complete data on lifestyle, work ability and sick leave for 10 355 employed persons aged 18–50 years. We modelled sick leave and work ability using multiple logistic regression, and introduced interaction terms to investigate whether associations with lifestyle factors were modified by asthma status. Results Several lifestyle risk factors and a multiple lifestyle risk index were associated with sick leave and reduced work ability score among persons both with and without physician-diagnosed asthma. A stronger association between lifestyle and sick leave among persons with asthma was confirmed by including interaction terms in the analysis: moderate lifestyle risk score * asthma OR = 1.4 (95% CI 1.02–2.1); high lifestyle risk score * asthma OR = 1.6 (95% CI 1.1–2.3); very high lifestyle risk score * asthma OR = 1.6 (95% CI 0.97–2.7); obesity * asthma OR = 1.5 (95% CI 1.02–2.1); past smoking * asthma OR = 1.4 (95% CI 1.01–1.9); and current smoking * asthma OR = 1.4 (95% CI 1.03–2.0). There was no significant difference in the association between lifestyle and work ability score among respondents with and without asthma. Conclusions In the present study, we found that physician-diagnosed asthma modified the association between lifestyle risk factors and sick leave. Asthma status did not significantly modify these associations with reduced work ability score. The results indicate that lifestyle changes could be of particular importance for employees with asthma.

• Klepaker, Geir; Svendsen, Martin Veel; Hertel, Jens Kristoffer; Holla, Øystein Lunde; Henneberger, Paul Keefer & Kongerud, Johny [Vis alle 7 forfattere av denne artikkelen] (2019). Influence of Obesity on Work ability, Respiratory Symptoms, and Lung Function in Adults with Asthma. Respiration. ISSN 0025-7931. 98(6), s. 473–481. doi: 10.1159/000502154. Fulltekst i vitenarkiv
• Kononova, Natalia; Sikkeland, Liv Ingunn Bjoner; Mahmood, Faiza; Vistnes, Maria; Kongerud, Johny & Einvik, Gunnar [Vis alle 7 forfattere av denne artikkelen] (2019). Annual decline in forced expiratory volume and airway inflammatory cells and mediators in a general population-based sample. BMC Pulmonary Medicine. ISSN 1471-2466. 19. doi: 10.1186/s12890-018-0765-7. Fulltekst i vitenarkiv
• Bugge, Anders; Lund, May-Brith; Valberg, Morten; Brustugun, Odd Terje; Solberg, Steinar & Kongerud, Johny (2018). Cause-specific death after surgical resection for early-stage non-small-cell lung cancer. European Journal of Cardio-Thoracic Surgery. ISSN 1010-7940. 53(1), s. 221–227. doi: 10.1093/ejcts/ezx274.
• Myrdal, Ole Henrik; Kanellopoulos, Adriani; Christiansen, Jon Runar; Ruud, Ellen; Edvardsen, Elisabeth & Kongerud, Johny [Vis alle 8 forfattere av denne artikkelen] (2018). Risk factors for impaired pulmonary function and cardiorespiratory fitness in very long-term adult survivors of childhood acute lymphoblastic leukemia after treatment with chemotherapy only*. Acta Oncologica. ISSN 0284-186X. 57(5), s. 658–664. doi: 10.1080/0284186X.2017.1423177. Vis sammendrag

  Background: Survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of late treatment-related side-effects. Data regarding prevalence and risk factors for impairments in pulmonary function and cardiorespiratory fitness are limited, and reported findings are inconsistent and inconclusive. Material and methods: In a cross-sectional study, 116 ALL survivors (median 5 years at diagnosis, 29 years at follow-up, 53% females) were examined, median 23 years after treatment with chemotherapy only. Individual cumulative doses of cytostatic agents were calculated. Methods included blood tests, echocardiography, pulmonary function tests and cardiorespiratory exercise test. Results: Females had lower % predicted gas diffusing capacity (DLCO) than males (mean [SD] 84 [13] versus 97 [14], p < .001). Impairment in DLCO was found in 34% females versus 7% males, p < .001. In a multiple linear regression model, female gender, body mass index (BMI) and smoking were risk factors for reduced % predicted DLCO, with a borderline significant effect of left ventricular ejection fraction (LVEF). Impaired cardiorespiratory fitness was found in 42% of the survivors, with a borderline increased risk in females, p = .06. Smoking and BMI were risk factors for reduced % predicted VO2peak. Subjects exposed to anthracyclines had lower LVEF% and % predicted VO2peak than those not exposed, (mean [SD] 56.2 [4.3] versus 59.2 [5.2], p = .01 and 86.9 [18.4] versus 92.8 [18.4], p = .03, respectively). Conclusions: Impairments in pulmonary function and cardiorespiratory fitness are common in very long-term survivors of childhood ALL. Risk factors are female gender, BMI and smoking. In order to preserve pulmonary function and cardiorespiratory fitness, we suggest increased attention and targeted advice on modifiable lifestyle factors such as smoking, inactivity and overweight.

• Fell, Anne Kristin Møller; Svendsen, Martin Veel; Kim, J L; Abrahamsen, Regine; Henneberger, Paul K. & Toren, K. [Vis alle 8 forfattere av denne artikkelen] (2018). Exposure to second-hand tobacco smoke and respiratory symptoms in non-smoking adults: cross-sectional data from the general population of Telemark, Norway. BMC Public Health. ISSN 1471-2458. 18(1). doi: 10.1186/s12889-018-5771-4.
• Clarhed, Ulrika K E; Svendsen, Martin Veel; Schiöler, Linus; Kongerud, Johny; Torén, Kjell & Hellgren, Johan [Vis alle 7 forfattere av denne artikkelen] (2018). Chronic Rhinosinusitis Related to Occupational Exposure: The Telemark Population Study. Journal of Occupational and Environmental Medicine. ISSN 1076-2752. 60(7), s. 656–660. doi: 10.1097/JOM.0000000000001312. Fulltekst i vitenarkiv
• Borander, Anne Katrine; Voie, Øyvind Albert; Longva, Kjetil Sager; Danielsen, Tor ERik; Grahnstedt, Svein & Sandvik, Leiv (2017). Military small arms fire in association with acute decrements in lung function. Occupational and Environmental Medicine. ISSN 1351-0711. 74(9), s. 639–644. doi: 10.1136/oemed-2016-104207.
• Abrahamsen, Regine; Fell, Anne Kristin Møller; Svendsen, Martin Veel; Andersson, E.; Torén, Kjell & Henneberger, Paul K. [Vis alle 7 forfattere av denne artikkelen] (2017). Association of respiratory symptoms and asthma with occupational exposures: findings from a population-based cross-sectional survey in Telemark, Norway. BMJ Open. ISSN 2044-6055. 7(3). doi: 10.1136/bmjopen-2016-014018. Fulltekst i vitenarkiv
• Bugge, Anders; Kongerud, Johny; Brunborg, Cathrine; Solberg, Steinar & Lund, May-Brith (2017). Gender-specific survival after surgical resection for early stage non-small cell lung cancer. Acta Oncologica. ISSN 0284-186X. 56(3), s. 448–454. doi: 10.1080/0284186X.2016.1253862.
• Christensen, Vivi Lycke; Holm, Are Martin; Kongerud, Johny; Bentsen, Signe Berit; Paul, Steven M. & Miaskowski, Christine [Vis alle 7 forfattere av denne artikkelen] (2016). Occurrence, Characteristics, and Predictors of Pain in Patients with Chronic Obstructive Pulmonary Disease. Pain Management Nursing. ISSN 1524-9042. 17(2), s. 107–118. doi: 10.1016/j.pmn.2016.01.002.
• Fell, Anne Kristin Møller; Abrahamsen, Regine; Henneberger, Paul K; Svendsen, Martin Veel; Andersson, E. & Toren, K. [Vis alle 7 forfattere av denne artikkelen] (2016). Breath-taking jobs: a case-control study of respiratory work disability by occupation in Norway. Occupational and Environmental Medicine. ISSN 1351-0711. 73(9), s. 600–606. doi: 10.1136/oemed-2015-103488. Vis sammendrag

  Background The current knowledge on respiratory work disability is based on studies that used crude categories of exposure. This may lead to a loss of power, and does not provide sufficient information to allow targeted workplace interventions and follow-up of patients with respiratory symptoms. Objectives The aim of this study was to identify occupations and specific exposures associated with respiratory work disability. Methods In 2013, a self-administered questionnaire was mailed to a random sample of the general population, aged 16–50, in Telemark County, Norway. We defined respiratory work disability as a positive response to the survey question: ‘Have you ever had to change or leave your job because it affected your breathing?’ Occupational exposures were assessed using an asthma-specific job-exposure matrix, and comparison of risks was made for cases and a median of 50 controls per case. Results 247 workers had changed their work because of respiratory symptoms, accounting for 1.7% of the respondents ever employed. The ‘breath-taking jobs’ were cooks/chefs: adjusted OR 3.6 (95% CI 1.6 to 8.0); welders: 5.2 (2.0 to 14); gardeners: 4.5 (1.3 to 15); sheet metal workers: 5.4 (2.0 to 14); cleaners: 5.0 (2.2 to 11); hairdressers: 6.4 (2.5 to 17); and agricultural labourers: 7.4 (2.5 to 22). Job changes were also associated with a variety of occupational exposures, with some differences between men and women. Conclusions Self-report and job-exposure matrix data showed similar findings. For the occupations and exposures associated with job change, preventive measures should be implemented.

• Bugge, Anders Standal; Lund, May-Brith; Brunborg, Cathrine; Solberg, Steinar & Kongerud, Johny (2016). Survival after surgical resection for lung cancer in patients with chronic obstructive pulmonary disease. Annals of Thoracic Surgery. ISSN 0003-4975. 101(6), s. 2125–2131. doi: 10.1016/j.athoracsur.2015.12.057. Vis sammendrag

  Background The best curable therapy for lung cancer is surgical resection. Chronic obstructive pulmonary disease (COPD) may influence survival, and lung function is crucial in the preoperative assessment. We hypothesized that COPD would influence survival after lung cancer resection. Methods During the period 2003 to 2013, 688 patients were operated on for stage I and II non-small cell lung cancer and prospectively registered. Spirometry was performed, and COPD categorized according to the definition by the Global Initiative for Chronic Obstructive Lung Disease. An explanatory strategy was used to investigate the relationship between severe COPD and survival. Results COPD was present in 455 patients (66.1%) and was severe in 51 (7.4%) and mild to moderate in 404 (58.7%), whereas 233 patients (33.9%) had normal lung function. Cumulative survival was similar in patients with normal lung function and patients with mild to moderate COPD. Patients with severe COPD had significantly reduced cumulative survival after 2 and 5 years of 63.5% (95% confidence interval [CI], 48.4% to 75.2%) and 41.8% (95% CI, 26.5% to 56.3%), respectively, compared with nonsevere COPD at 81.7% (95% CI, 77.4% to 85.2%) and 61.3% (95% CI, 55.3% to 66.6%), respectively. Severe COPD was associated with a 69% increased risk of mortality (adjusted hazard ratio, 1.69; 95% CI, 1.12 to 2.55). Conclusions With careful preoperative selection, surgical resection may safely be offered to lung cancer patients with severe COPD. However, these patients have decreased long-term overall survival. Similar survival between patients with normal lung function and mild to moderate COPD suggests that similar indications for lung cancer operations may be applied.

• Sikkeland, Liv Ingunn Bjoner; Alexis, Neil E.; Fry, Rebecca C.; Martin, Elizabeth; Danielsen, Tor ERik & Søstrand, Per [Vis alle 7 forfattere av denne artikkelen] (2016). Inflammation in induced sputum after aluminium oxide exposure: An experimental chamber study. Occupational and Environmental Medicine. ISSN 1351-0711. 73(3), s. 199–205. doi: 10.1136/oemed-2015-103254.
• Abrahamsen, Regine; Svendsen, Martin Veel; Henneberger, Paul K.; Gundersen, Gølin Finkenhagen; Torén, Kjell & Kongerud, Johny [Vis alle 7 forfattere av denne artikkelen] (2016). Non-response in a cross-sectional study of respiratory health in Norway. BMJ Open. ISSN 2044-6055. 6(1). doi: 10.1136/bmjopen-2015-009912.
• Sikkeland, Liv Ingunn Bjoner; Johnsen, Helle Laier; Riste, Tonje Bøyum; Alexis, Neil E.; Halvorsen, Bente & Søyseth, Vidar [Vis alle 7 forfattere av denne artikkelen] (2016). Sputum neutrophils are elevated in smelter workers, and systemic neutrophils are associated with rapid decline in FEV1. Occupational and Environmental Medicine. ISSN 1351-0711. 73(7), s. 459–466. doi: 10.1136/oemed-2015-103083.
• Nordby, Karl-Christian; Notø, Hilde Pettersen; Wijnand, Eduard; Skogstad, Marit; Fell, Anne Kristin Møller & Thomassen, Yngvar [Vis alle 12 forfattere av denne artikkelen] (2016). Thoracic dust exposure is associated with lung function decline in cement production workers. European Respiratory Journal. ISSN 0903-1936. 48(2), s. 331–339. doi: 10.1183/13993003.02061-2015.
• Søyseth, Vidar; Henneberger, Paul K; Einvik, Gunnar; Virji, Mohammed Abbas; Bakke, Berit & Kongerud, Johny (2016). Annual decline in forced expiratory volume is steeper in aluminum potroom workers than in workers without exposure to potroom fumes. American Journal of Industrial Medicine. ISSN 0271-3586. 59(4), s. 322–329. doi: 10.1002/ajim.22570.
• Søyseth, Vidar; Henneberger, Paul; Virji, Mohammed Abbas; Bakke, Berit & Kongerud, Johny (2015). Construction of a job exposure matrix to dust, fluoride, and polycyclic aromatic hydrocarbons in the Norwegian aluminum industry using prediction models. Annals of Occupational Hygiene. ISSN 0003-4878. 59(9), s. 1106–1121. doi: 10.1093/annhyg/mev069.
• Søyseth, Vidar; Johnsen, Helle Laier; Henneberger, Paul K. & Kongerud, Johny (2015). Increased decline in pulmonary function among employees in Norwegian smelters reporting work-related asthma-like symptoms. Journal of Occupational and Environmental Medicine. ISSN 1076-2752. 57(9), s. 1004–1008. doi: 10.1097/JOM.0000000000000518. Vis sammendrag

  Objective: To investigate associations between work-related asthma-like symptoms (WASTH) and annual pulmonary function decline among employees of 18 Norwegian smelters. Methods: A 5-year longitudinal study in which WASTH was defined as a combination of dyspnea and wheezing that improved on rest days and vacation. Results: A total of 12,966 spirometry examinations were performed in 3084 employees. Crude annual decline in forced expiratory volume in 1 second (FEV1) (dFEV1) was 32.9 mL/yr (95% confidence interval, 30.5 to 35.3), and crude annual decline in forced vital capacity (FVC) (dFVC) was 40.9 mL/yr (37.8 to 43.9). After adjustment for relevant covariates, employees reporting WASTH showed higher dFEV1 by 16.0 m:/yr (3.4 to 28.6) and higher dFVC by 20.5 mL/yr (6.0 to 35.0) compared with employees not reporting WASTH. Conclusion: Work-related asthma-like symptom was associated with greater annual declines in FEV1 and FVC, indicating a restrictive pattern.

• Oksholm, Trine; Rustøen, Tone; Cooper, Bruce; Paul, Steven M.; Solberg, Steinar & Henriksen, Kari [Vis alle 8 forfattere av denne artikkelen] (2015). Trajectories of symptom occurrence and severity from before through five months after lung cancer surgery. Journal of Pain and Symptom Management. ISSN 0885-3924. 49(6), s. 995–1015. doi: 10.1016/j.jpainsymman.2014.11.297.
• Espinoza, Andreas Westenvik; Neumann, Kirill; Halvorsen, Per Steinar; Sundset, Arve; Kongerud, Johny & Fosse, Erik (2015). Critical airway obstruction: Challenges in airway management and ventilation during therapeutic bronchoscopy. Journal of Bronchology & Interventional Pulmonology. ISSN 1944-6586. 22(1), s. 41–47. doi: 10.1097/LBR.0000000000000127.
• Nemer, Maysaa Y K Sadeya; Sikkeland, Liv Ingunn Bjoner; Kasem, Mayes; Kristensen, Petter; Nijem, Khaldoun & Bjertness, Espen [Vis alle 10 forfattere av denne artikkelen] (2015). Airway inflammation and ammonia exposure among female Palestinian hairdressers: A cross-sectional study. Occupational and Environmental Medicine. ISSN 1351-0711. 72(6), s. 428–434. doi: 10.1136/oemed-2014-102437.
• Oksholm, Trine; Miaskowsky, Christine; Solberg, Steinar; Lie, Irene; Cooper, Bruce & Paul, Steven M. [Vis alle 8 forfattere av denne artikkelen] (2015). Changes in symptom occurrence and severity before and after lung cancer surgery. Cancer Nursing. ISSN 0162-220X. 38(5), s. 351–357. doi: 10.1097/NCC.0000000000000198.
• Fell, Anne Kristin Møller; Aasen, Tor Olav Brøvig & Kongerud, Johny (2014). Arbeidsrelatert kols. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 134(22), s. 2158–2163. doi: 10.4045/tidsskr.14.0255.
• Aasen, Tor Olav Brøvig & Kongerud, Johny (2014). Arbeidsrelatert astma : diagnostikk og oppfølging. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 134(20), s. 1955–1959. doi: 10.4045/tidsskr.13.1225.
• Sikkeland, Liv Ingunn Bjoner; Samersaw-Lund, May Brit & Kongerud, Johny (2014). Immunological Analysis of Induced Sputum in Work Exposures. Journal of Environmental Immunology and Toxicology. ISSN 2225-1219. 1(4), s. 183–189. doi: 10.7178/jeit.10.
• Bugge, Anders Standal; Naalsund, Anne; Johnsrud, Kjersti; Berstad, Audun Elnæs; Samersaw-Lund, May Brit & Kongerud, Johny (2014). PET-CT i utredningen av lungekreft ved Rikshospitalet 2007 - 11. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 134(9), s. 938–944. doi: 10.4045/tidsskr.12.1512. Vis sammendrag

  BAKGRUNN PET-CT er et hjelpemiddel ved utredning av lungekreft for å finne operable pasienter. Undersøkelsen anbefales hos de fleste pasienter med ikke-småcellet lungekreft som etter primærutredning antas å ha kurativ sykdom. Vi ønsket å beregne nytteverdien av PET-CT hos antatt operable pasienter som har fått utført undersøkelsen ved Rikshospitalet. MATERIALE OG METODE Pasienter innlagt til lungekreftutredning registreres fortløpende i avdelingens kvalitetsdatabase. Vi har analysert data for perioden 2007 – 11 for pasienter som etter primærutredning hadde en antatt operabel tumor. Av kapasitetshensyn ble noen operert uten forutgående PET-CT. RESULTATER Av 651 antatt operable pasienter ble PET-CT utført hos 533, hvorav 403 (76 %)ble operert. Vi beregnet at undersøkelsen hadde sensitivitet 78 % (95 % KI 70 – 86) og spesifisitet 88 % (95 % KI 85 – 91), positiv prediktiv verdi 64 % (95 % KI 55 – 72) og negativ prediktiv verdi 94 % (95 % KI 91 – 96) for spredning til mediastinale lymfeknuter. Diagnostisk nøyaktighet var 86 % (95 % KI 83 – 89) med kappaoverensstemmelse 0,61 (95 % KI 0,53 – 0,69) mellom PET-CT og faktiske funn av maligne eller benigne mediastinale lymfeknuter. FORTOLKNING PET-CT var et nyttig verktøy for utvelgelse av potensielt operable lungekreftpasienter ved Rikshospitalet 2007 – 11. Forutsatt at populasjonen vi undersøker med PET-CT ikke endrer seg, kan pasienter med negativ PET-CT med få unntak henvises direkte til operasjon uten ytterligere invasiv utredning.

• Voie, Øyvind Albert; Borander, Anne Katrine; Sikkeland, Liv Ingunn Bjoner; Grahnstedt, Svein; Johnsen, Arnt Magne & Danielsen, Tor ERik (2014). Health effects after firing small arms comparing leaded and unleaded ammunition. Inhalation Toxicology. ISSN 0895-8378. 26(14), s. 873–879. doi: 10.3109/08958378.2014.970783.
• Kongerud, Johny & Søyseth, Vidar (2014). Respiratory disorders in aluminum smelter workers. Journal of Occupational and Environmental Medicine. ISSN 1076-2752. 56(5), s. S60–S70. doi: 10.1097/JOM.0000000000000105.
• Færden, Karl; Lund, May-Brith; Aaløkken, Trond Mogens; Wijnand, Eduard; Søstrand, Per & Langård, Sverre [Vis alle 7 forfattere av denne artikkelen] (2014). Hypersensitivity pneumonitis in a cluster of sawmill workers: A 10-year follow-up of exposure, symptoms, and lung function. International journal of occupational and environmental health. ISSN 1077-3525. 20(2), s. 167–173. doi: 10.1179/2049396714Y.0000000063.
• Søyseth, Vidar; Johnsen, Helle Laier & Kongerud, Johny (2013). Respiratory hazards of metal smelting. Current opinion in pulmonary medicine. ISSN 1070-5287. 19(2), s. 158–162. doi: 10.1097/MCP.0b013e32835ceeae.
• Oksholm, Trine; Miaskowski, Christine; Kongerud, Johny; Cooper, Bruce; Paul, Steven M. & Lærum, Line Pedersen [Vis alle 7 forfattere av denne artikkelen] (2013). Does age influence the symptom experience of lung cancer patients prior to surgery? Lung Cancer. ISSN 0169-5002. 82(1), s. 156–161. doi: 10.1016/j.lungcan.2013.06.016.
• Gabrielsen, Anne Marie; Lund, May-Brith; Kongerud, Johny; Viken, Karl Erik; Røislien, Jo & Hjelmesæth, Jøran [Vis alle 7 forfattere av denne artikkelen] (2013). Pulmonary function and blood gases after gastric bypass and lifestyle intervention: a comparative study. Clinical Obesity. ISSN 1758-8103. 3, s. 117–123. doi: 10.1111/cob.12024.
• Johnsen, Helle Laier; Bugge, Merete Drevvatne; Føreland, Solveig; Kjuus, Helge; Kongerud, Johny & Søyseth, Vidar (2013). Dust exposure is associated with increased lung function loss among workers in the Norwegian silicon carbide industry. Occupational and Environmental Medicine. ISSN 1351-0711. 70(11), s. 803–809. doi: 10.1136/oemed-2012-101068.
• Neumann, Kirill; Sundset, Arve; Espinoza, Andreas Westenvik; Kongerud, Johny & Fosse, Erik (2013). Changes in Quality of Life, Dyspnea Scores, and Lung Function in Lung Cancer Patients With Airway Obstruction After a Therapeutic Bronchoscopy. Journal of Bronchology & Interventional Pulmonology. ISSN 1944-6586. 20(2), s. 134–139. doi: 10.1097/LBR.0b013e3182917280.
• Gregersen, Stina; Holm, Are Martin; Fevang, Børre; Ueland, Thor; Sikkeland, Liv Ingunn Bjoner & Aaløkken, Trond Mogens [Vis alle 11 forfattere av denne artikkelen] (2013). Lung disease, T-cells and inflammation in common variable immunodeficiency disorders. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 73(6), s. 514–522. doi: 10.3109/00365513.2013.819523.
• Auråen, Henrik; Mollnes, Tom Eirik; Bjørtuft, Øystein; Bakkan, Per Arne; Geiran, Odd & Kongerud, Johny [Vis alle 8 forfattere av denne artikkelen] (2013). Multiorgan procurement increases systemic inflammation in brain dead donors. Clinical Transplantation. ISSN 0902-0063. 27(4), s. 613–618. doi: 10.1111/ctr.12175.
• Sjåheim, Tone Bjørg; Bjørtuft, Øystein; Drabløs, P.-A.; Kongerud, Johny & Halstensen, Trond Sundby (2013). Increased Bronchial Density of CD25+Foxp3+ Regulatory T Cells in Occupational Asthma: Relationship to Current Smoking. Scandinavian Journal of Immunology. ISSN 0300-9475. 77(5), s. 398–404. doi: 10.1111/sji.12035. Vis sammendrag

  To identify activated T cell subset in the asthmatic bronchia, we developed a triple-colour immunohistofluorescence labelling technique on cryo-section to discriminate activated CD4+CD25+ T cells, (effector T cells) from Foxp3+ regulatory T cells (Treg). Additional coexpression of activation and proliferation markers was also examined in situ. Bronchial biopsies were taken from 20 aluminium potroom workers (12 smokers) with asthma (>12% reversibility), 15 non-asthmatic potroom workers (7 smokers) and 10 non-smoking, non-exposed controls. Non-smoking asthmatics had significantly higher subepithelial density of both Tregs, effector T cells, activated (HLA-DR+) CD8+ and activated CD4+ T cells. Moreover, both Tregs, effector T cells and CD8+ T cells proliferated in the non-smoking asthmatics, only. Although smoking asthmatics had no asthma-associated increase in bronchial T cell, both had a significantly increase in effector T cell to Treg ratios. The significantly increased bronchial density of Tregs, effector T cells, proliferative T cells and activated CD8+ T cells in non-smoking asthmatics clearly showed that both the effector T cells and the inhibitory Treg system were activated in asthma.

• Sikkeland, Liv Ingunn Bjoner; Dahl, Christen Peder; Ueland, Thor; Andreassen, Arne K.; Gude, Einar & Edvardsen, Thor [Vis alle 12 forfattere av denne artikkelen] (2012). Increased levels of inflammatory cytokines and endothelin-1 in alveolar macrophages from patients with chronic heart failure. PLOS ONE. ISSN 1932-6203. 7(5:e36815). doi: 10.1371/journal.pone.0036815.
• Søyseth, Vidar; Johnsen, Helle Laier; Henneberger, Paul K. & Kongerud, Johny (2012). The incidence of work-related asthma-like symptoms and dust exposure in Norwegian smelters. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X. 185(12), s. 1280–1285. doi: 10.1164/rccm.201110-1809OC. Vis sammendrag

  Rationale: The prevalence of respiratory symptoms amongemployees in smelters is positively associated with dust exposure. Objectives: To investigate the association between the incidence of work-related asthma-like symptoms (WASTH) and dust exposure. Methods: All the employees were invited to participate in a 5-year longitudinal study. The outcome of WASTH was defined as the combination of dyspnea and wheezing improving on rest days or vacation in an individual who had no asthma previously. Information about smoking and occupational status was obtained from a questionnaire. A job exposure matrix of total dust was developed. Multivariate data analyses were performed using Cox regression. Measurements and Main Results: The total follow-up time of the employees (n ¼ 2,476) was 8,469 years, and the median follow-up time for participantswas 4.0 years.During the follow-up, 91employees developed WASTH, and the corresponding incidence rate for WASTH per 1,000 person-years was 8.9 (7.3–10.9) (95% confidence interval in parentheses). The risk ratio ofWASTH increased significantly (P ¼ 0.0001)with dust exposure in the middle andhighcategories (1.0–2.9 and>3.0mg/m3). Stratifiedanalyses showedthat theeffect ofcurrent dust exposure varied with both previous exposure (PE) to dust and fumes (P ¼ 0.006) and airflow limitation (AFL) (P ¼ 0.033). The final analyses showedthat the risk ratios forWASTHper 1mg/m3 increase in current dust exposure were 1.1 (0.93–1.2), 1.4 (1.1–1.8), 1.6 (1.1–2.3), and 1.9 (1.2–3.0) for the categories (PE1/AFL2), (PE2/AFL2), (PE1/ AFL1, and (PE2/AFL1). Conclusions: In conclusion, dust exposure was associated with an increased incidence of WASTH. Keywords: work-related asthma-like symptoms; incidence; dust exposure

• Sikkeland, Liv Ingunn Bjoner; Wijnand, Eduard; Skogstad, Marit; Alexis, Neil E. & Kongerud, Johny (2012). Recovery from workplace-induced airway inflammation 1 year after cessation of exposure. Occupational and Environmental Medicine. ISSN 1351-0711. 69(10), s. 721–726. doi: 10.1136/oemed-2011-100632. Vis sammendrag

  Background Bacterial single-cell protein (BSCP) constitutes of dried bacterial mass which is used as protein enrichment in animal and fish feed. In the production of BSCP, workers are exposed to organic dust containing high levels of endotoxins (arithmetic mean 390 EU/m3 in the moderate exposure and 5800–11 000 EU/m3 in the high exposure groups) and have elevated levels of sputum neutrophils and cytokines associated with exposure. Objective The aim of the present study was to investigate if airway inflammation among the workers had declined 1 year after cessation of exposure. Methods Twenty-four non-smoking production workers (age 28–52) with a work history of 2–7 years were included in the study. Measurements Markers of airways inflammation and innate immune function (using flow cytometry) were assessed in an exposure period and 1 year after cessation of exposure. Results Sputum neutrophil proportion and numbers were significantly decreased 1 year after cessation of exposure to BSCP (43% vs 71%, 186 vs 598 neutrophils/mg sputum; p<0.001) as were eNO (17 ppb vs 21 ppb (p=0.01) and interleukin-1β (p<0.05) and interleukin-8 (p<0.05). Neutrophils had enhanced expression of CD11b/CR3 (p<0.01) and CD16/FcγRIII (p<0.001) and macrophages had lower expression of CD86 (p<0.01) 1 year after cessation of exposure. Conclusions One year after closure of the plant airway neutrophils and exhaled NO levels resolved to lower levels and cell surface phenotypes associated with innate immune function recovered to higher levels, indicating that these changes were partly reversible among workers who were no longer exposed to endotoxins in a BSCP plant.

• Søyseth, Vidar; Johnsen, Helle Laier; Bugge, Merete Drevvatne & Kongerud, Johny (2012). The association between symptoms and exposure is stronger in dropouts than in non-dropouts among employees in Norwegian smelters: a five-year follow-up study. International Archives of Occupational and Environmental Health. ISSN 0340-0131. 85(1), s. 27–33. doi: 10.1007/s00420-011-0631-x.
• Skogstad, Marit; Sikkeland, Liv Ingunn Bjoner; Øvstebø, Reidun; Foss, Kari Bente; Heldal , Kari Emilie & Skare, Øivind [Vis alle 9 forfattere av denne artikkelen] (2012). Long-term occupational outcomes of endotoxin exposure and the effect of exposure cessation. Occupational and Environmental Medicine. ISSN 1351-0711. 69(2), s. 107–112. doi: 10.1136/oem.2010.062414.
• Sundset, Arve; Lund, May-Brith; Hansen, Gunnar; Bjørtuft, Øystein; Kongerud, Johny & Geiran, Odd (2012). Airway Complications after Lung Transplantation: Long-Term Outcome of Silicone Stenting. Respiration. ISSN 0025-7931. 83(3), s. 245–252. doi: 10.1159/000334905.
• Neyman, Kirill; Sundset, Arve; Naalsund, Anne; Espinoza, Andreas Westenvik; Solberg, Steinar & Kongerud, Johny [Vis alle 7 forfattere av denne artikkelen] (2012). Endoscopic Treatment of Bronchial Carcinoids in Comparison to Surgical Resection: A Retrospective Study. Journal of Bronchology & Interventional Pulmonology. ISSN 1944-6586. 19(1), s. 29–34. doi: 10.1097/LBR.0b013e3182446b52.
• Nordby, Karl-Christian; Fell, Anne Kristin Møller; Notø, Hilde Pettersen; Wijnand, Eduard; Skogstad, Marit & Thomassen, Yngvar [Vis alle 9 forfattere av denne artikkelen] (2011). Exposure to thoracic dust, airway symptoms, and lung function in cement production workers. European Respiratory Journal. ISSN 0903-1936. 38(6), s. 1278–1286. doi: 10.1183/09031936.00007711.
• Fell, Anne Kristin Møller; Notø, Hilde Pettersen; Skogstad, Marit; Nordby, Karl-Christian; Wijnand, Eduard & Svendsen, Martin Veel [Vis alle 9 forfattere av denne artikkelen] (2011). A cross-shift study of lung function, exhaled nitric oxide and inflammatory markers in blood in Norwegian cement production workers. Occupational and Environmental Medicine. ISSN 1351-0711. 68(11), s. 799–805. doi: 10.1136/oem.2010.057729.
• Søyseth, Vidar; Johnsen, Helle Laier; Drevvatne Bugge, Merete; Hetland, Siri & Kongerud, Johny (2011). Incidence of Airflow Limitation Among Employees in Norwegian Smelters. American Journal of Industrial Medicine. ISSN 0271-3586. 54(9), s. 707–713. doi: 10.1002/ajim.20946.
• Gabrielsen, Anne Marie; Lund, May Brit; Kongerud, Johny; Viken, Karl Erik; Røislien, Jo & Hjelmesæth, Jøran (2011). The Relationship Between Anthropometric Measures, Blood Gases, and Lung Function in Morbidly Obese White Subjects. Obesity Surgery. ISSN 0960-8923. 21(4), s. 485–491. doi: 10.1007/s11695-010-0306-9.
• Søyseth, Vidar; Johnsen, Helle Laier; Drevvatne Bugge, Merete; Hetland, Siri & Kongerud, Johny (2011). Prevalence of airflow limitation among employees in Norwegian smelters: a longitudinal study. Occupational and Environmental Medicine. ISSN 1351-0711. 68(1), s. 24–29. doi: 10.1136/oem.2009.049452.
• Lohne, Vibeke; Drangsholt, Hanne Camilla Heer; Andersen, Marit Helen; Miaskowsky, Christine; Kongerud, Johny & Rustøen, Tone (2010). Qualitative study of pain of patients with chronic obstructive pulmonary disease. Heart & Lung. ISSN 0147-9563. 39(3), s. 226–234. doi: 10.1016/j.hrtlng.2009.08.002.
• Gregersen, Stina; Aaløkken, TM; Mynarek, Georg; Fevang, Børre; Holm, Are Martin & Ueland, Thor [Vis alle 10 forfattere av denne artikkelen] (2010). Development of pulmonary abnormalities in patients with common variable immunodeficiency: associations with clinical and immunologic factors. Annals of Allergy, Asthma & Immunology. ISSN 1081-1206. 104(6), s. 503–510. doi: 10.1016/j.anai.2010.04.015.
• Fell, Anne Kristin Møller; Sikkeland, Liv Ingunn Bjoner; Svendsen, Martin Veel & Kongerud, Johny (2010). Airway inflammation in cement production workers. Occupational and Environmental Medicine. ISSN 1351-0711. 67(6), s. 395–400. doi: 10.1136/oem.2009.047852.
• Johnsen, Helle Laier; Hetland, Siri M.; Saltyte-Benth, Jurate; Kongerud, Johny & Søyseth, Vidar (2010). Dust Exposure Assessed by a Job Exposure Matrix Is Associated with Increased Annual Decline in FEV1 A 5-year Prospective Study of Employees in Norwegian Smelters. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X. 181(11), s. 1234–1240. doi: 10.1164/rccm.200809-1381OC.
• Kongerud, Johny & Sikkeland, Liv Ingunn Bjoner (2009). Indusert sputum: metode for diagnostikk av lungesykdom. Fagbladet Allergi i praksis. ISSN 0806-5462. 4, s. 20–29.
• Lund, May Brit; Sikkeland, Liv Ingunn Bjoner & Kongerud, Johny (2009). Utredning av yrkesastma på ulike nivåer i helsevesenet. Fagbladet Allergi i praksis. ISSN 0806-5462. 1, s. 16–23.
• Fell, Anne Kristin Møller; Sikkeland, Liv Ingunn Bjoner; Svendsen, MV & Kongerud, Johny (2009). Airway Inflammation in Cement Production Workers. Occupational and Environmental Medicine. ISSN 1351-0711. doi: 10.1136/oem.2009.047852.
• Gregersen, Stina; Aaløkken, Trond Mogens; Mynarek, Georg; Kongerud, Johny; Aukrust, Pål & Frøland, Stig Sophus [Vis alle 7 forfattere av denne artikkelen] (2009). High resolution computed tomography and pulmonary function in common variable immunodeficiency. Respiratory Medicine. ISSN 0954-6111. 103, s. 873–880. doi: 10.1016/j.rmed.2008.12.015.
• Kongerud, Johny; Laier Johnsen, H & Søyseth, V (2009). Obstruktiv lungesykdom i norsk aluminiums- og smelteverksindustri. Fagbladet Allergi i praksis. ISSN 0806-5462. 1, s. 34–39.
• Sikkeland, Liv Ingunn Bjoner; Eduard, W; Larsen, Astrid Marie; Thorgersen, Ebbe Billmann; Haug, T. & Aukrust, Pål [Vis alle 9 forfattere av denne artikkelen] (2009). Occupational exposure to bacterial single cell protein induces inflammation in lung and blood. Inhalation Toxicology. ISSN 0895-8378. 21(8-11), s. 674–681. doi: 10.1080/08958370802491425.
• Skogstad, M; Sikkeland, Liv Ingunn Bjoner; Øvstebø, Reidun; Foss Haug, Kari Bente; Kierulf, Peter & Heldal, KK [Vis alle 8 forfattere av denne artikkelen] (2009). Does endotoxin exposure affect lung function and induce systemic inflammation in workers handling bacterial single cell protein? Scandinavian Journal of Work, Environment and Health. ISSN 0355-3140. 7, s. 36–40.

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• Sikkeland, Liv Ingunn Bjoner; Durheim, Michael; Riste, Tonje Bøyum; Kongerud, Johny; Alexis, Neil E. & Holm, Are Martin (2021). Relation of sputum neutrophilia to the development of chronic lung allograft dysfunction after lung transplantation. Clinical Transplantation. ISSN 0902-0063. 35(3), s. 1–5. doi: 10.1111/ctr.14188.
• Sikkeland, Liv Ingunn Bjoner; Borander, Anne Katrine; Voie, Øyvind Albert; Aass, Hans Christian Dalsbotten; Øvstebø, Reidun & Aukrust, Pål [Vis alle 8 forfattere av denne artikkelen] (2018). Systemic and Airway Inflammation After Exposure to Fumes from Military Small Arms. American Journal of Respiratory and Critical Care Medicine. ISSN 1073-449X. 197(10), s. 1349–1353. doi: 10.1164/rccm.201709-1857LE.
• Christensen, Vivi Lycke; Holm, Are Martin; Kongerud, Johny; Bentsen, Signe Berit; Paul, Steven M & Miaskowski, Christine [Vis alle 8 forfattere av denne artikkelen] (2017). Smerter hos pasienter med kronisk obstruktiv lungesykdom (KOLS).
• Fell, Anne Kristin Møller; Kim, Jeong-Lim; Abrahamsen, Regine; Svendsen, Martin Veel; Torén, Kjell & Henneberger, Paul K [Vis alle 7 forfattere av denne artikkelen] (2016). Household smoking and respiratory health in Telemark, Norway - 10 years after the introduction of a smoking ban. European Respiratory Journal. ISSN 0903-1936.
• Fell, Anne Kristin Møller; Kim, Jeong-Lim; Abrahamsen, Regine; Svendsen, Martin Veel; Torén, Kjell & Henneberger, Paul K [Vis alle 7 forfattere av denne artikkelen] (2016). Household smoking and respiratory health in Telemark, Norway - 10 years after the introduction of a smoking ban.
• Abrahamsen, Regine; Fell, Anne Kristin Møller; Svendsen, Martin Veel; Andersson, Eva; Torén, Kjell & Henneberger, Paul K [Vis alle 7 forfattere av denne artikkelen] (2016). Occupational groups associated with asthma related respiratory symptoms in a cross-sectional study from Norway. European Respiratory Journal. ISSN 0903-1936.
• Abrahamsen, Regine; Fell, Anne Kristin Møller; Svendsen, Martin Veel; Andersson, Eva; Torén, Kjell & Henneberger, Paul K [Vis alle 7 forfattere av denne artikkelen] (2016). Occupational groups associated with asthma related respiratory symptoms in a cross-sectional study from Norway.
• Abrahamsen, Regine; Svendsen, Martin Veel; Henneberger, Paul K; Torén, Kjell; Kongerud, Johny & Fell, Anne Kristin Møller (2016). Exposure to damp and mould at home in relation to respiratory symptoms in the Telemark study, Norway. European Respiratory Journal. ISSN 0903-1936.
• Abrahamsen, Regine; Svendsen, Martin Veel; Henneberger, Paul K; Torén, Kjell; Kongerud, Johny & Fell, Anne Kristin Møller (2016). Exposure to damp and mould at home in relation to respiratory symptoms in the Telemark study, Norway.
• Abrahamsen, Regine; Svendsen, Martin Veel; Henneberger, Paul K; Gundersen, Gølin Finkenhagen; Torén, Kjell & Kongerud, Johny [Vis alle 7 forfattere av denne artikkelen] (2015). Non-response in a population-based study of respiratory health in Norway. European Respiratory Journal. ISSN 0903-1936.
• Abrahamsen, Regine; Svendsen, Martin Veel; Henneberger, Paul K; Gundersen, Gølin Finkenhagen; Torén, Kjell & Kongerud, Johny [Vis alle 7 forfattere av denne artikkelen] (2015). Non-response in a population-based study of respiratory health in Norway.
• Fell, Anne Kristin Møller; Abrahamsen, Regine; Henneberger, Paul K; Svendsen, Martin Veel; Torén, Kjell & Kongerud, Johny (2015). Late braking abstract: Breath-taking jobs: Respiratory work disability by occupation. ERS Poster discussion. European Respiratory Journal. ISSN 0903-1936.
• Fell, Anne Kristin Møller; Abrahamsen, Regine; Henneberger, Paul K; Svendsen, Martin Veel; Torén, Kjell & Kongerud, Johny (2015). Late braking abstract: Breath-taking jobs: Respiratory work disability by occupation. ERS Poster discussion.
• Aasen, Tor Olav Brøvig & Kongerud, Johny (2015). T.O.B. Aasen &amp; J. Kongerud svarer. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(1), s. 11–11. doi: 10.4045/tidsskr.14.1488.
• Aasen, Tor Olav Brøvig & Kongerud, Johny (2015). T.O.B. Aasen & J. Kongerud svarer. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(1), s. 11–12. doi: 10.4045/tidsskr.14.1487.
• Oksholm, Trine; Rustøen, Tone; Miaskowski, Christine; Paul, Steven; Solberg, Steinar & Cooper, Bruce A. [Vis alle 7 forfattere av denne artikkelen] (2014). Changes in symptoms from before to five months after lung cancer surgery.
• Oksholm, Trine; Rustøen, Tone; Kongerud, Johny & Ekstedt, Mirjam (2014). Postsurgical transfer between hospitals is a risk situation for lung cancer patients.
• Fell, Anne Kristin Møller; Abrahamsen, Regine; Svendsen, Martin Veel; Torén, Kjell; Henneberger, Paul K & Kongerud, Johny (2014). Respiratory symptoms and change of workplace in the general population of Telemark.
• Aasen, Tor Olav Brøvig & Kongerud, Johny (2014). Arbeidsmiljøet gir fremdeles sykdom. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 134(20), s. 1916–1916. doi: 10.4045/tidsskr.14.1220.
• Oksholm, Trine; Rustøen, Tone; Miaskowski, Christine; Paul, Steven; Cataldo, Janine & Kongerud, Johny (2013). Reliability of and correlates with a measure of lung cancer stigma in Norwegian patients who underwent lung cancer surgery .
• Oksholm, Trine; Rustøen, Tone; Cooper, Bruce; Miaskowski, Christine & Kongerud, Johny (2013). Changes in symptom occurrence rating before and following lung cancer surgery.
• Nemer, Maysaa Yousef Khaled; Kasem, Mayes; Sikkeland, Liv Ingunn Bjoner; Kristensen, Petter; Nijem, Khaldoun Issa & Kongerud, Johny [Vis alle 8 forfattere av denne artikkelen] (2013). Airways inflammation among female Palestinian hairdressers. A cross-sectional study. Norsk Epidemiologi, Supplement. ISSN 0803-4206. 23, s. 20–20.
• Nemer, Maysaa Yousef Khaled; Kasem, Mayes; Sikkeland, Liv Ingunn Bjoner; Kristensen, Petter; Nijem, Khaldoun Issa & Kongerud, Johny [Vis alle 8 forfattere av denne artikkelen] (2013). Airways inflammation among female Palestinian hairdressers. A cross-sectional study.
• Søyseth, Vidar; Johnsen, Helle Laier & Kongerud, Johny (2012). Merchant seafaring: a changing and hazardous occupation Response. Occupational and Environmental Medicine. ISSN 1351-0711. 69(9), s. 690–690. doi: 10.1136/oemed-2012-100695.
• Auråen, Henrik; Mollnes, Tom Eirik; Kongerud, Johny; Bjørtuft, Øystein; Geiran, Odd & Fiane, Arnt E [Vis alle 7 forfattere av denne artikkelen] (2012). Procedure for solid organ recovery leads to systemic inflammatory response. The Journal of Heart and Lung Transplantation. ISSN 1053-2498. 31(4), s. S220–S220. doi: 10.1016/j.healun.2012.01.651.
• Kongerud, Johny (2009). Occupational asthma--not only for occupational health physicians! Tidsskrift for Den norske legeforening. ISSN 0029-2001. 129, s. 647–648. doi: 10.4045/tidsskr.09.0145.
• Oksholm, Trine; Rustøen, Tone & Kongerud, Johny (2016). Patients' symptom experiences before and after lung cancer surgery. Predictors of patients’ symptom burden. University of Oslo. Faculty of Medicine. ISSN 978-82-8333-035-9. Vis sammendrag

  I 2013 ble 601 pasienter operert for lungekreft i Norge. De fleste av disse var over 70 år. Trine Oksholm har i sitt doktorgradsarbeid undersøkt symptombelastning og livskvalitet hos pasienter med lungekreft før og etter operasjon. Dette ble kartlagt ved hjelp av spørreskjema hos 270 pasienter. Pasientene fylte først ut spørreskjema før operasjon, deretter etter en og fem måneder etter operasjonen. Avhandlingen består av tre delarbeider. I det første ble det undersøkt forskjeller i symptombelastning hos yngre og eldre pasienter før lungekreftoperasjon. Pasientene hadde i gjennomsnitt 9 symptomer før operasjon. Symptombelastningen var relativt lik for yngre og eldre pasienter. I det andre delarbeidet ble det sett på hvordan symptomene endret seg fra før operasjon til en måned etter operasjon. Gjennomsnittlig antall symptomer var da steget til 13. Hele 4 av 5 pasienter opplevde kortpustethet, å ha lite energi, smerte og søvnighet en måned etter operasjon. Det tredje delarbeidet viste at antall symptomer ble redusert fra en til 5 måneder, men det var fortsatt høyere enn før operasjon. Hele 79 % av pasientene var kortpustet 5 måneder etter operasjonen, mens 71 % hadde lite energi og 56 % hadde smerter. Studien viser at pasienter med lungekreft har mange symptomer både før og etter operasjon. Antall symptomer før operasjon samt antall tilleggs-sykdommer påvirket hvor mange symptomer pasientene hadde etter operasjon. Det viste seg videre at 5-10 % av pasientene hadde så mange alvorlige og kraftige symptomer at de trengte spesiell oppfølging. På tross av anbefaling gjennom internasjonale retningslinjer hadde kun 32 % av pasientene fått fysioterapi og kun 16 % hadde vært på rehabiliteringsopphold. Studien viser også at mens 30 % av pasientene var i arbeid før operasjon var kun 9 % i arbeid 5 måneder etter operasjonen. Konklusjonen er at helsepersonell bør informere pasientene om vanlig symptomforløp etter en lungekreftoperasjon. Det bør også utvikles tiltak for å hjelpe pasientene til symptomlindring eller eventuelt til å mestre symptomene etter lungekreftoperasjon

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