Lill Trine Nyfløt

• Bonnichsen, Maja Lecic; Qvigstad, Elisabeth; Nyfløt, Lill Trine; Haugen, Guttorm Nils; Denault, William Robert Paul & Roland, Marie Cecilie (2026). Effects of gestational weight gain and HbA1C on fetal growth and birthweight in women with obesity. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. doi: 10.1111/aogs.70298. Fulltekst i vitenarkiv
• Mentzoni, Camilla Tjønneland; Røe, Kjerstine; Bjellmo, Solveig; Carlsen, Marte Irene Skille; Christiansen, Marit Halonen & Fjeldstad, Tora Sandvik [Vis alle 15 forfattere av denne artikkelen] (2026). Learning opportunities in eclampsia care: A ten‐year audit from Norway, 2013–2022. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 105, s. 1767–1777. doi: 10.1111/aogs.70280. Fulltekst i vitenarkiv Vis sammendrag

  Introduction The World Health Organization recommends surveillance, including audits with case reviews of severe maternal morbidities such as eclampsia, to improve obstetric outcomes. We aimed to audit eclampsia and to identify learning opportunities in eclampsia care in Norway. Material and Methods Our study population included all women discharged with a diagnosis of eclampsia (ICD‐10: O15) and with a documented generalized seizure in medical records at two university hospitals in Norway from 2013 to 2022. An eclampsia working group developed a digital eclampsia case report form for gathering clinical information from medical records. Based on a structured summary of information from the digital case report form, the group reviewed the care for women with eclampsia. Each case was discussed and reviewed according to the clinical guidelines by the group. Learning opportunities to improve care were identified and classified according to whether they contributed to the outcome. Results Among 93 139 deliveries, 22 women with an initial eclampsia diagnosis were identified (2.4 per 10 000). Subsequent clinical information identified an alternative probable etiology of seizures in five women. None of the 22 women received magnesium sulfate prior to the seizure, and cerebral imaging was performed in 11 of 22 women. In 18 women, learning opportunities were identified, and for eight women, a different management could potentially have prevented eclampsia. The eclampsia working group identified learning opportunities related to underuse of magnesium sulfate prophylaxis when indicated, inadequate management of hypertension both before and after eclamptic seizure, underuse of cerebral imaging as a diagnostic tool, and lack of follow‐up consultation with an obstetrician in women diagnosed with eclampsia. Conclusions Learning opportunities were found in 18 of 22 women, and improvements in care could potentially have changed the outcome for eight of the women. This audit highlights the importance of differential diagnostic consideration for seizures in pregnant and postpartum women, the use of prophylactic magnesium sulfate when indicated, and the diagnosis and management of hypertension in pregnancy. Eclampsia audits should be incorporated into national routine surveillance and learning systems to improve obstetric care.

• Kvalvik, Sedina Atic; Åmark, Hanna; Helmig, Rikke Bek; Gissler, Mika; Nyfløt, Lill Trine & Skrede, Steinar [Vis alle 9 forfattere av denne artikkelen] (2025). Maternal deaths from sepsis in the Nordic countries during 2005–2021: A descriptive study. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 104(9), s. 1783–1792. doi: 10.1111/aogs.70011. Fulltekst i vitenarkiv Vis sammendrag

  Introduction: Maternal sepsis is a heterogenous condition which can arise from several different infections during and after pregnancy. Common for all etiologies is a high mortality rate. In a global perspective, maternal sepsis is an important contributor to maternal death. This study aimed to evaluate the clinical management of maternal deaths from sepsis in the Nordic countries and identify areas for improved clinical handling. Material and Methods: We used data from the Nordic Maternal Mortality Collaboration including maternal deaths from the five Nordic countries from 2005 till 2021, identified through linked registers. The national audit groups assessed each maternal death based on hospital records and classified it according to cause and quality of management. We formulated learning points to improve future clinical care in cases of maternal sepsis. Results: In total, 267 maternal deaths were identified, equaling a maternal mortality rate of 5.9 per 100 000 live births (95% CI 5.25–6.62). Maternal sepsis accounted for 9.7% of the maternal deaths (n = 26), ranking sepsis the fifth leading cause. Nongenital sepsis and genital tract sepsis numbers were almost equal. Substandard care was identified in 57% of cases with nongenital infections, and in 83% of genital tract sepsis cases. Improvements in care that possibly could have influenced the outcome were noted in 29% and 67% of cases, respectively. In nongenital sepsis, delayed recognition of sepsis and delayed administration of antimicrobial therapy were the commonest elements in substandard care. Delayed recognition of sepsis, delayed administration of antimicrobial therapy, and postponed or lacking surgical source control were the main elements in substandard care of genital tract sepsis. Conclusions: In the Nordic countries, sepsis was the fifth leading cause of maternal deaths during 2005–2021. In one-third of maternal deaths from nongenital sepsis and two-thirds of maternal deaths from genital tract sepsis, clinical measures could have reduced the risk of fatal outcome, emphasizing the need for maximal awareness and improved clinical handling.

• Pettersen, Silje; Falk, Ragnhild Sørum; Vangen, Siri & Nyfløt, Lill Trine (2025). Tone or tissue? A comparison of trends and risk factors of severe postpartum hemorrhage according to uterine atony or retained tissue in a hospital setting. PLOS ONE. 20(2). doi: 10.1371/journal.pone.0318770. Fulltekst i vitenarkiv
• Bonnichsen, Maja Lecic; Gunnes, Nina; Nyfløt, Lill Trine; Haugen, Guttorm Nils & Roland, Marie Cecilie (2024). Prepregnancy body mass index and visceral fat exhibit divergent associations with metabolic factors in pregnant women with obesity: A Norwegian cohort study. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 103(12), s. 2511–2521. doi: 10.1111/aogs.14968. Fulltekst i vitenarkiv Vis sammendrag

  Introduction Pregnancy involves changes in maternal metabolism that differ between normal-weight women and women with overweight or obesity, including changes in glucose, insulin, lipids, and adipokines. These changes contribute to altered risk profiles for adverse outcomes for both mother and child during pregnancy, childbirth, and postpartum. We explored associations between visceral fat and prepregnancy body mass index (pBMI), respectively, with glucose and lipid metabolism, as well as with adipokines and C-reactive protein (CRP), measured fasting in early and late pregnancy. We hypothesized that among women with pBMI ≥35 kg/m2, visceral fat measured around gestational week 18 (visceral fat18) would show associations with greater number of metabolic variables during pregnancy, than pBMI. Material and Methods This prospective longitudinal cohort study was conducted at the Department of Gynecology and Obstetrics at Drammen Hospital from 2016 to 2019. We included 166 nulliparous (47.6%) and parous pregnant women with pBMI ≥35 kg/m2 and singleton pregnancy. Women with type 1 diabetes were excluded. We evaluated associations of pBMI and visceral fat estimated with bioimpedance weight around gestational week 18 (visceral fat18) with fasting metabolic measures around gestational weeks 18 and 36 using median regression models. We used the paired t-test or the Wilcoxon signed-rank test, as appropriate, to analyze changes in metabolic measures from early to late pregnancy, and median regression to estimate crude and adjusted differences in medians of 21 maternal metabolic measures associated with one-unit changes in pBMI and visceral fat18, respectively. Results pBMI and visceral fat18 were highly correlated and showed associations with similar metabolic measures in pregnancy in crude analysis. After mutual adjustment for each other in addition to age and parity, pBMI was associated with glucose metabolism, in particular fasting insulin, whereas visceral fat18 was primarily associated with leptin. Conclusions Among pregnant women with BMI ≥35 kg/m2, easily obtainable pBMI and the more resource-demanding estimate of visceral fat18 exhibit divergent associations with metabolic measures; pBMI was positively associated with insulin, glucose, and HbA1c, while visceral fat18 was positively associated with leptin. We did not find visceral fat18 to be associated with greater number of metabolic factors than pBMI.

• Varpula, Reetta; Äyräs, Outi; Aabakke, Anna J. M.; Klungsøyr, Kari; Svanvik, Teresia & Kanerva, Julia [Vis alle 22 forfattere av denne artikkelen] (2024). Early suppression policies protected pregnant women from COVID-19 in 2020: A population-based surveillance from the Nordic countries. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 103(6), s. 1063–1072. doi: 10.1111/aogs.14808. Fulltekst i vitenarkiv Vis sammendrag

  Introduction The Coronavirus 2019 Disease (COVID-19) pandemic reached the Nordic countries in March 2020. Public health interventions to limit viral transmission varied across different countries both in timing and in magnitude. Interventions indicated by an Oxford Stringency Index ≥50 were implemented early (March 13–17, 2020) in Denmark, Finland, Norway and Iceland, and on March 26, 2020 in Sweden. The aim of the current study was to assess the incidence of COVID-19-related admissions of pregnant women in the Nordic countries in relation to the different national public health strategies during the first year of the pandemic. Material and methods This is a meta-analysis of population-based cohort studies in the five Nordic countries with national or regional surveillance in the Nordic Obstetric Surveillance System (NOSS) collaboration: national data from Denmark, Finland, Iceland and Norway, and regional data covering 31% of births in Sweden. The source population consisted of women giving birth in the included areas March 1–December 31, 2020. Pregnant women with a positive SARS-CoV-2 PCR test ≤14 days before hospital admission were included, and admissions were stratified as either COVID-19-related or non-COVID (other obstetric healthcare). Information about public health policies was retrieved retrospectively. Results In total, 392 382 maternities were considered. Of these, 600 women were diagnosed with SARS-CoV-2 infection and 137 (22.8%) were admitted for COVID-19 symptoms. The pooled incidence of COVID-19 admissions per 1000 maternities was 0.5 (95% confidence interval [CI] 0.2 to 1.2, I2 = 77.6, tau2 = 0.68, P = 0.0), ranging from no admissions in Iceland to 1.9 admissions in the Swedish regions. Interventions to restrict viral transmission were less stringent in Sweden than in the other Nordic countries. Conclusions There was a clear variation in pregnant women's risk of COVID-19 admission across countries with similar healthcare systems but different public health interventions to limit viral transmission. The meta-analysis indicates that early suppression policies protected pregnant women from severe COVID-19 disease prior to the availability of individual protection with vaccines.

• Hofer, Stefan; Blaha, Jan; Collins, Peter W.; Ducloy-Bouthors, Anne-Sophie; Guasch, Emilia & Labate, Francesco [Vis alle 10 forfattere av denne artikkelen] (2023). Haemostatic support in postpartum haemorrhage: A review of the literature and expert opinion. European Journal of Anaesthesiology. ISSN 0265-0215. 40(1), s. 29–38. doi: 10.1097/EJA.0000000000001744. Fulltekst i vitenarkiv
• Pettersen, Silje; Falk, Ragnhild Sørum; Vangen, Siri & Nyfløt, Lill Trine (2023). Exploring trends of severe postpartum haemorrhage: a hospital-based study. BMC Pregnancy and Childbirth. 23, s. 1–11. doi: 10.1186/s12884-023-05702-6. Fulltekst i vitenarkiv Vis sammendrag

  Background Over the past two decades several high-income countries have reported increased rates of postpartum haemorrhage (PPH). Many of the studies are registry studies with limited access to detailed information. We aimed to explore trends of severe PPH in the largest labour ward in Norway during a 10-year period with a hospital based study. Our population constituted all women who gave birth after week 22 at Oslo University Hospital between 2008 and 2017. The main outcome measure was severe PPH, defined as registered blood loss greater than 1500 ml, or transfusion of blood products due to PPH. Methods We estimated the incidence of severe PPH and blood transfusions, and performed temporal trend analysis. We performed Poisson regression analysis to investigate associations between pregnancy characteristics and severe PPH, presented using crude incidence rate ratios (IRR) with 95% confidence intervals (CI)s. We also estimated annual percentage change of the linear trends. Results Among 96 313 deliveries during the 10-year study period, 2621 (2.7%) were diagnosed with severe PPH. The incidence rate doubled from 17.1/1000 to 2008 to 34.2/1000 in 2017. We also observed an increased rate of women receiving blood transfusion due to PPH, from 12.2/1000 to 2008 to 27.5/1000 in 2017. The rates of invasive procedures to manage severe PPH did not increase, and we did not observe a significant increase in the number of women defined with maternal near miss or massive transfusions. No women died due to PPH during the study period. Conclusion We found a significant increasing trend of severe PPH and related blood transfusions during the 10-year study period. We did not find an increase in massive PPH, or in invasive management, and we suspect that the rise can be at least partly explained by increased awareness and early intervention contributing to improved registration of severe PPH.

• Diguisto, Caroline; Saucedo, Monica; Kallianidis, Athanasios; Bloemenkamp, Kitty; Bødker, Birgit & Buoncristiano, Marta [Vis alle 14 forfattere av denne artikkelen] (2022). Maternal mortality in eight European countries with enhanced surveillance systems: descriptive population based study. The BMJ. 379(e070621). doi: 10.1136/bmj-2022-070621. Fulltekst i vitenarkiv
• Bremerthun, Silje Pettersen; Falk, Ragnhild Sørum; Vangen, Siri & Nyfløt, Lill Trine (2022). Peripartum hysterectomy due to severe postpartum hemorrhage: A hospital-based study. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 101, s. 819–826. doi: 10.1111/aogs.14358. Fulltekst i vitenarkiv Vis sammendrag

  Introduction A peripartum hysterectomy is typically performed as a lifesaving procedure in obstetrics to manage severe postpartum hemorrhage. Severe hemorrhages that lead to peripartum hysterectomies are mainly caused by uterine atony and placenta accreta spectrum disorders. In this study, we aimed to estimate the incidence, risk factors, causes and management of severe postpartum hemorrhage resulting in peripartum hysterectomies, and to describe the complications of the hysterectomies. Material and methods Eligible women had given birth at gestational week 23+0 or later and had a postpartum hemorrhage ≥1500 mL or a blood transfusion, due to postpartum hemorrhage, at Oslo University Hospital, Norway, between 2008 and 2017. Among the eligible women, this study included those who underwent a hysterectomy within the first 42 days after delivery. The Norwegian Medical Birth Registry provided the reference group. We used Poisson regression to estimate adjusted incidence rate ratios with 95% confidence intervals to identify clinical factors associated with peripartum hysterectomy. Results The incidence of hysterectomies with severe postpartum hemorrhage was 0.44/1000 deliveries (42/96313). Among the women with severe postpartum hemorrhage, 1.6% ended up with a hysterectomy (42/2621). Maternal age ≥40, previous cesarean section, multiple pregnancy and placenta previa were associated with a significantly higher risk of hysterectomy. Placenta accreta spectrum disorders were the most frequent cause of hemorrhage that resulted in a hysterectomy (52%, 22/42) and contributed to most of the complications following the hysterectomy (11/15 women with complications). Conclusions The rate of peripartum hysterectomies at Oslo University Hospital was low, but was higher than previously reported from Norway. Risk factors included high maternal age, previous cesarean section, multiple pregnancy and placenta previa, well known risk factors for placenta accreta spectrum disorders and severe postpartum hemorrhage. Placenta accreta spectrum disorders were the largest contributor to hysterectomies and complications.

• Engjom, Hilde Marie; Aabakke, Anna J. M.; Klungsøyr, Kari; Svanvik, Teresia; Äyräs, Outi & Jonasdottir, Eva [Vis alle 16 forfattere av denne artikkelen] (2021). COVID‐19 in pregnancy – characteristics and outcomes of pregnant women admitted to hospital because of SARS‐CoV‐2 infection in the Nordic countries. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 100(9), s. 1611–1619. doi: 10.1111/aogs.14160. Fulltekst i vitenarkiv Vis sammendrag

  Introduction Population-based studies about the consequences of SARS-CoV-2 infection (COVID-19) in pregnancy are few and have limited generalizability to the Nordic population and healthcare systems. Material and methods This study examines pregnant women with COVID-19 in the five Nordic countries. Pregnant women were included if they were admitted to hospital between 1 March and 30 June 2020 and had a positive SARS-CoV-2 PCR test ≤14 days prior to admission. Cause of admission was classified as obstetric or COVID-19-related. Results In the study areas, 214 pregnant women with a positive test were admitted to hospital, of which 56 women required hospital care due to COVID-19. The risk of admission due to COVID-19 was 0.4/1000 deliveries in Denmark, Finland and Norway, and 3.8/1000 deliveries in the Swedish regions. Women hospitalized because of COVID-19 were more frequently obese (p < 0.001) and had a migrant background (p < 0.001) compared with the total population of women who delivered in 2018. Twelve women (21.4%) needed intensive care. Among the 56 women admitted due to COVID-19, 48 women delivered 51 infants. Preterm delivery (n = 12, 25%, p < 0.001) and cesarean delivery (n = 21, 43.8%, p < 0.001) were more frequent in women with COVID-19 compared with women who delivered in 2018. No maternal deaths, stillbirths or neonatal deaths were reported. Conclusions The risk of admission due to COVID-19 disease in pregnancy was low in the Nordic countries. A fifth of the women required intensive care and we observed higher rates of preterm and cesarean deliveries. National public health policies appear to have had an impact on the risk of admission due to severe COVID-19 disease in pregnancy. Nordic collaboration is important in collecting robust data and assessing rare outcomes.

• Nyfløt, Lill Trine; Johansen, Marianne; Mulic-Lutvica, Ajlana; Gissler, Mika; Bødker, Birgit & Bremme, Katarina [Vis alle 8 forfattere av denne artikkelen] (2021). The impact of cardiovascular diseases on maternal deaths in the Nordic countries. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 100, s. 1273–1279. doi: 10.1111/aogs.14104. Fulltekst i vitenarkiv Vis sammendrag

  Introduction Cardiovascular diseases have become increasingly important as a cause of maternal death in the Nordic countries. This is likely to be associated with a rising incidence of pregnant women with congenital and acquired cardiac diseases. Through audits, we aim to prevent future maternal deaths by identifying causes of death and suboptimal factors in the clinical management. Material and methods Maternal deaths in the Nordic countries from 2005 to 2017 were identified through linked registers. The national audit groups performed case assessments based on hospital records, classified the cause of death, and evaluated the standards of clinical care provided. Key messages were prepared to improve treatment. Results We identified 227 maternal deaths, giving a maternal mortality rate of 5.98 deaths per 100 000 live births. The most common cause of death was cardiovascular disease (n = 36 deaths). Aortic dissection/rupture, myocardial disease, and ischemic heart disease were the most common diagnoses. In nearly 60% of the cases, the disease was not recognized before death. In more than half of the deaths, substandard care was identified (59%). In 11 deaths (31%), improvements to care that may have made a difference to the outcome were identified. Conclusions Between 2005 and 2017, cardiovascular diseases were the most common causes of maternal deaths in the Nordic countries. There appears to be a clear potential for a further reduction in these maternal deaths. Increased awareness of cardiac symptoms in pregnant women seems warranted.

• Nyfløt, Lill Trine; Ellingsen, Liv; Yli, Branislava Markovic; Øian, Pål & Vangen, Siri (2018). Maternal deaths from hypertensive disorders: lessons learnt. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 97(8), s. 976–987. doi: 10.1111/aogs.13357. Fulltekst i vitenarkiv
• Nyfløt, Lill Trine; Sandven, Irene; Stray-Pedersen, Babill; Pettersen, Silje; Al-Zirqi, Iqbal Ahmad Abdelwahab & Rosenberg, Margit [Vis alle 8 forfattere av denne artikkelen] (2017). Risk factors for severe postpartum hemorrhage: A case-control study. BMC Pregnancy and Childbirth. 17:17, s. 1–9. doi: 10.1186/s12884-016-1217-0. Fulltekst i vitenarkiv Vis sammendrag

  Background In high-income countries, the incidence of severe postpartum hemorrhage (PPH) has increased. This has important public health relevance because severe PPH is a leading cause of major maternal morbidity. However, few studies have identified risk factors for severe PPH within a contemporary obstetric cohort. Methods We performed a case-control study to identify risk factors for severe PPH among a cohort of women who delivered at one of three hospitals in Norway between 2008 and 2011. A case (severe PPH) was classified by an estimated blood loss ≥1500 mL or the need for blood transfusion for excessive postpartum bleeding. Using logistic regression, we applied a pragmatic strategy to identify independent risk factors for severe PPH. Results Among a total of 43,105 deliveries occurring between 2008 and 2011, we identified 1064 cases and 2059 random controls. The frequency of severe PPH was 2.5% (95% confidence interval (CI): 2.32–2.62). The most common etiologies for severe PPH were uterine atony (60%) and placental complications (36%). The strongest risk factors were a history of severe PPH (adjusted OR (aOR) = 8.97, 95% CI: 5.25–15.33), anticoagulant medication (aOR = 4.79, 95% CI: 2.72–8.41), anemia at booking (aOR = 4.27, 95% CI: 2.79–6.54), severe pre-eclampsia or HELLP syndrome (aOR = 3.03, 95% CI: 1.74–5.27), uterine fibromas (aOR = 2.71, 95% CI: 1.69–4.35), multiple pregnancy (aOR = 2.11, 95% CI: 1.39–3.22) and assisted reproductive technologies (aOR = 1.88, 95% CI: 1.33–2.65). Conclusions Based on our findings, women with a history of severe PPH are at highest risk of severe PPH. As well as other established clinical risk factors for PPH, a history of severe PPH should be included as a risk factor in the development and validation of prediction models for PPH.

• Nyfløt, Lill Trine; Stray-Pedersen, Babill; Forsen, Lisa & Vangen, Siri (2017). Duration of labor and the risk of severe postpartum hemorrhage: A case-control study. PLOS ONE. 12(4). doi: 10.1371/journal.pone.0175306. Fulltekst i vitenarkiv Vis sammendrag

  Objective Our main objective was to investigate the association between duration of active labor and severe postpartum hemorrhage. We examined the effect of the total duration of active labor, the effect of each stage of active labor, and the gradient effect of duration of labor on severe postpartum hemorrhage. Methods A case-control study was generated from a source population of all women admitted for delivery at Oslo University Hospital and Drammen Hospital in Buskerud municipality during the time period January 1, 2008 to December 31, 2011. The study population included all cases of severe postpartum hemorrhage (n = 859) and a random sample of controls (n = 1755). Severe postpartum hemorrhage was defined as postpartum blood loss >= 1500 mL or need for blood transfusion. Prolonged labor was defined as duration of active labor >12 hours according to the definition of the World Health Organization. We used logistic multi-variable regression in the analysis. Results We observed a significantly longer mean duration of labor in women who experienced severe postpartum hemorrhage compared to controls (5.4 versus 3.8 hours, p<0.001). Women with severe postpartum hemorrhage also had a longer duration of all stages of active labor compared to controls. The association between the duration of active labor and severe postpartum changed from a linear dose-response association to a threshold association after adjusting for augmentation with oxytocin, induction of labor, primiparity, and fever during labor. Compared to controls, women with severe postpartum hemorrhage were more likely to have a prolonged labor >12 hours (adjusted odds ratio = 2.44, 95% confidence interval: 1.69-3.53, p< 0.001). Conclusion Prolonged active labor (duration > 12 hours) was associated with severe postpartum hemorrhage. Increased vigilance seems required when the labor is prolonged to reduce the risk of severe postpartum hemorrhage.

• Nyfløt, Lill Trine; Sandven, Irene; Oldereid, Nan Birgitte; Stray-Pedersen, Babill & Vangen, Siri (2017). Assisted reproductive technology and severe postpartum haemorrhage: a case–control study. BJOG: An International Journal of Obstetrics and Gynaecology. ISSN 1470-0328. 124(8), s. 1198–1205. doi: 10.1111/1471-0528.14471. Fulltekst i vitenarkiv
• Vangen, Siri; Bødker, Birgit; Ellingsen, Liv; Saltvedt, Sissel; Gissler, Mika & Geirsson, Reynir T. [Vis alle 7 forfattere av denne artikkelen] (2017). Maternal deaths in the Nordic countries. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 96(9), s. 1112–1119. doi: 10.1111/aogs.13172. Fulltekst i vitenarkiv
• Vangen, Siri; Ellingsen, Liv; Andersgaard, Alice Beathe; Jacobsen, Anne Flem; Lorentzen, Bjørg & Nyfløt, Lill Trine [Vis alle 10 forfattere av denne artikkelen] (2014). Mødredødsfall i Norge 2005-09. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 134(8), s. 836–839. doi: 10.4045/tidsskr.13.0203. Fulltekst i vitenarkiv

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• Carlsen, Marte Irene Skille; Uleberg, Oddvar; Mohus, Randi Marie; Mentzoni, Camilla Tjønneland; Nyfløt, Lill Trine & Klungsøyr, Kari [Vis alle 7 forfattere av denne artikkelen] (2025). Incidence of peripartum hysterectomy due to postpartum hemorrhage: A national population‐based cohort study. Fulltekst i vitenarkiv
• Miltenburg, Andrea Solnes; Bains, Sukhjeet Kaur; Strøm-Roum, Ellen Marie; Vartdal, Vegard Weyergang; Sørbye, Ingvil Krarup & Alnæs-Katjavivi, Patji [Vis alle 8 forfattere av denne artikkelen] (2023). Svangerskap, fødsel og barseltid – mer enn bare overlevelse. Tidsskrift for Den norske legeforening (Tidsskriftet). ISSN 0029-2001. 143(15), s. 1–3. doi: 10.4045/tidsskr.23.0500. Fulltekst i vitenarkiv
• Bonnichsen, Maja Lecic; Nyfløt, Lill Trine; Haugen, Guttorm Nils & Roland, Marie Cecilie (2023). SEVERE MATERNAL OBESITY AND ACTIVE LABOUR. Fulltekst i vitenarkiv Vis sammendrag

  Introduction/Purpose Maternal obesity is associated with prolonged duration of labour and arrested labour along with extended list of adverse outcomes for mother and child. To study expulsion time (ET) in induced and non-induced, nulliparous and parous parturients with severe pre-pregnant obesity (pBMI≥35). Methods "Healthy mother-lifelong health for mother and child" was a prospective, longitudinal, observational study, conducted at Drammen Hospital between 2016 and 2019, including 166 pregnant women with pBMI≥35. We collected detailed data on labour induction, duration of active labour (AL, from 4 cm dilatation and contractions) including ET, and mode of delivery. We compared groups by median regression, adjusting for parity. Results Among the 125 women (75%) with vaginal birth, 90 women (72%) were induced and 8 women (6%) were delivered by vacuum. 54% of induced women and 63% of non-induced were parous. Median duration of AL was 3 hrs. (P0; 4 hrs. vs. P≥1; 2 hrs. p=0.091) in non-induced labours and 3.5 hrs. (P0; 5 hrs. vs. P≥1; 2 hrs. p=0.008) in induced labours, while ET was 19.5 min (P0; 29min vs. P≥1; 11min, p=0.006) and 17 min (P0; 25.5min vs. P≥1; 8, p=0.001) respectively. Neither duration of active labour (p=0.540) or expulsion time (p=0.583) was significantly different in the two labour groups. Conclusions Despite the majority of labours being induced, we found that 75% delivered vaginally with short median duration of active labour and expulsion time. We found no significant differences in active labour or expulsion time when comparing non-induced and induced labours.

• Nyfløt, Lill Trine & Sitras, Vasilis (2018). Strategies to reduce global maternal mortality. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 97(6), s. 639–640. doi: 10.1111/aogs.13356. Fulltekst i vitenarkiv
• Bødker, Birgit; Bremme, Katarina; Geirsson, Reynir; Gissler, Mika; Grunewald, Charlotta & Hvidman, Lone [Vis alle 12 forfattere av denne artikkelen] (2012). Maternal mortality in the Nordic countries The establishment of a Nordic maternal mortality collaboration. Acta Obstetricia et Gynecologica Scandinavica. ISSN 0001-6349. 91, s. 46–47. Fulltekst i vitenarkiv

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