Bakgrunn
- Administrativ leder, Senter for fremragende forskning, PRIMA, 2023-
- Prosjektleder/forsker, Malmberg-gruppen 2018-
- Administrativ koordinator for Senter for immunregulering og K.G. Jebsen-senter for cøliakiforskning, 2014-2018
- Forsker/postdok, immunologi, 2005-2014
- Doktorgrad i immunologi ved Universitetet i Oslo, 2005.
- Master of Science, Biologi, Fysiologi, Universitetet i Oslo, 1998.
Emneord:
Immunologi,
immunterapi,
NK-celler
Publikasjoner
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Haroun-Izquierdo, Alvaro; Vincenti, Marianna; Netskar, Herman Krogstad; van Ooijen, Hanna; Zhang, Bin & Bendzick, Laura
[Vis alle 30 forfattere av denne artikkelen]
(2022).
Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia.
Journal for ImmunoTherapy of Cancer (JITC).
10:e005577(11),
s. 1–13.
doi:
10.1136/jitc-2022-005577.
Fulltekst i vitenarkiv
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Sudworth, Amanda; Vaage, John T.; Inngjerdingen, Marit & Kveberg, Lise
(2017).
Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+ subset.
Journal of Leukocyte Biology.
ISSN 0741-5400.
102(6),
s. 1289–1298.
doi:
10.1189/jlb.1HI0517-177RR.
Fulltekst i vitenarkiv
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Kveberg, Lise; Sudworth, Amanda; Todros-Dawda, Izabela Malgorzata; Inngjerdingen, Marit & Vaage, John Torgils
(2015).
Functional characterization of a conserved pair of NKR-P1 receptors expressed by NK cells and T lymphocytes in liver and gut.
European Journal of Immunology.
ISSN 0014-2980.
45(2),
s. 501–512.
doi:
10.1002/eji.201444710.
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Todros-Dawda, Izabela Malgorzata; Kveberg, Lise; Vaage, John Torgils & Inngjerdingen, Marit
(2014).
The tetraspanin CD53 modulates responses from activating NK cell receptors, promoting LFA-1 activation and dampening NK cell effector functions.
PLOS ONE.
ISSN 1932-6203.
9(5).
doi:
10.1371/journal.pone.0097844.
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Daws, Michael Rory; Dai, Kezheng; Zinöcker, Severin; Naper, Christian; Kveberg, Lise & Hedrich, Hans J
[Vis alle 8 forfattere av denne artikkelen]
(2012).
Identification of an MHC Class I Ligand for the Single Member of a Killer Cell Lectin-like Receptor Family, KLRH1.
Journal of Immunology.
ISSN 0022-1767.
189(11),
s. 5178–5184.
doi:
10.4049/jimmunol.1201983.
Vis sammendrag
Natural killer cells are able to recognize and kill target cells according to differences in MHC class I expression. In rodents, the Ly49 receptors are primarily responsible for this MHC differentiation. We previously described the cloning of a novel C-type lectin–like receptor, KLRH1, encoded in the NK complex adjacent to the Ly49 genes and expressed by subsets of NK and NKT cells. MHC influence on selection of KLRH1+ NK cells in congenic strains suggested that KLRH1 may have an MHC ligand, although we were unable to identify any such ligand. In this study, we have used a sensitive reporter system and Fc fusion protein to demonstrate that KLRH1 binds specifically to the classical MHC class I molecule RT1-A2 of the RT1n haplotype. Cytolytic activity of KLRH1-transfected RNK-16 cells was also inhibited by target cells expressing RT1-A2n. Thus, KLRH1 represents a novel family of MHC allele–specific inhibitory receptors expressed by NK cells.
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Inngjerdingen, Marit; Kveberg, Lise & Vaage, John Torgils
(2012).
A Novel NKR-P1B(bright) NK Cell Subset Expresses an Activated CD25(+)CX(3)CR1(+)CD62L(-)CD11b(-)CD27(-) Phenotype and Is Prevalent in Blood, Liver, and Gut-Associated Lymphoid Organs of Rats.
Journal of Immunology.
ISSN 0022-1767.
188(6),
s. 2499–2508.
doi:
10.4049/jimmunol.1003939.
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Kveberg, Lise; Dai, Kezheng; Inngjerdingen, Marit; Brooks, Colin G. ; Fossum, Sigbjørn & Vaage, John Torgils
(2011).
Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse.
Immunogenetics.
ISSN 0093-7711.
63(7),
s. 429–436.
doi:
10.1007/s00251-011-0520-1.
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Naper, Christian; Kveberg, Lise; Engh, Espen; Nestvold, Janne M.; Rolstad, Bent & Vaage, John Torgils
(2010).
Partial NK cell tolerance induced by radioresistant host cells in rats transplanted with MHC-mismatched bone marrow.
International Immunology.
ISSN 0953-8178.
22(12),
s. 973–980.
doi:
10.1093/intimm/dxq452.
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Kveberg, Lise; Jiminèz-Royo, Pilar; Naper, Christian; Rolstad, Bent; Butcher, Geoffrey W & Vaage, John Torgils
[Vis alle 7 forfattere av denne artikkelen]
(2010).
Two complementary rat NK cell subsets, Ly49s3(+) and NKR-P1B(+), differ in phenotypic characteristics and responsiveness to cytokines.
Journal of Leukocyte Biology.
ISSN 0741-5400.
88(1),
s. 87–93.
doi:
10.1189/jlb.0110039.
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Kveberg, Lise; Dai, Kezheng; Westgaard, Ingunn Hagen; Daws, Michael Rory; Fossum, Sigbjørn & Naper, Christian
[Vis alle 7 forfattere av denne artikkelen]
(2009).
Two major groups of rat NKR-P1 receptors can be distinguished based on chromosomal localization, phylogenetic analysis and Clr ligand binding.
European Journal of Immunology.
ISSN 0014-2980.
39(2),
s. 541–551.
doi:
10.1002/eji.200838891.
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Kveberg, Lise; Dai, Kezheng; Dissen, Erik; Ryan, James C.; Rolstad, Bent & Vaage, John Torgils
[Vis alle 7 forfattere av denne artikkelen]
(2006).
Strain-dependent expression of four structurally related rat Ly49 receptors; correlation with NK gene complex haplotype and NK alloreactivity.
Immunogenetics.
ISSN 0093-7711.
58(11),
s. 905–916.
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Kveberg, Lise; Inngjerdingen, Marit & Rolstad, Bent
(2006).
The novel inhibitory NKR-P1C receptor and ly49s3 identify two complementary, functionally distinct NK cell subsets in rats.
Journal of Immunology.
ISSN 0022-1767.
176,
s. 4133–4140.
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Naper, Christian; Dai, Kezheng; Kveberg, Lise; Rolstad, Bent; Niemi, EC & Vaage, John Torgils
[Vis alle 7 forfattere av denne artikkelen]
(2005).
Two structurally related rat Ly49 receptors with opposing functions (Ly49 stimulatory receptor 5 and Ly49 inhibitory receptor 5) recognize nonclassical MHC class Ib-encoded target ligands.
Journal of Immunology.
ISSN 0022-1767.
174.
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Kveberg, Lise; Ryan, JC; Rolstad, Bent & Inngjerdingen, Marit
(2005).
Expression of regulator of G protein signalling proteins in natural killer cells, and their modulation by Ly49A and Ly49D.
Immunology.
ISSN 0019-2805.
115.
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Kveberg, Lise; Bryceson, Yenan; Inngjerdingen, Marit; Rolstad, Bent & Maghazachi, Azzam A.
(2002).
Sphingosine 1 phosphate induces the chemotaxis of human natural killer cells. Role for heterotrimeric G proteins and phosphoinositide 3 kinases.
European Journal of Immunology.
ISSN 0014-2980.
32,
s. 1856–1864.
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Naper, Christian; Hayashi, Shigenari; Kveberg, Lise; Niemi, Eréne C.; Lanier, Lewis L. & Vaage, John Torgils
[Vis alle 7 forfattere av denne artikkelen]
(2002).
Ly-49s3 is a promiscuous activating rat NK cell receptor for nonclassical MHC class I-encoded target ligands.
Journal of Immunology.
ISSN 0022-1767.
169,
s. 22–30.
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Naper, Christian; Hayashi, Shigenari; Løvik, Guro; Kveberg, Lise; Niemi, Eréne C. & Rolstad, Bent
[Vis alle 9 forfattere av denne artikkelen]
(2002).
Characterization of a novel killer cell lectin-like receptor (KLRH1) expressed by alloreactive rat NK cells.
Journal of Immunology.
ISSN 0022-1767.
s. 5147–5154.
Se alle arbeider i Cristin
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Kveberg, Lise; Dai, Kezheng; Martinsen, Stine; Fossum, Sigbjørn & Vaage, John Torgils
(2009).
Phylogenetic and functional conservation of the NKR-P1G NK receptor in rat and mouse.
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Kveberg, Lise; Fossum, Sigbjørn & Vaage, John Torgils
(2009).
Phylogenetic and functional conservation of the NKR-P1G receptor in rat and mouse.
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Kveberg, Lise; Westgaard, Ingunn Hagen; Dai, Kezheng; Daws, Michael Rory; Fossum, Sigbjørn & Naper, Christian
[Vis alle 7 forfattere av denne artikkelen]
(2007).
The NKR-P1 family of receptors in rat recognizes C-type lectin-related molecules.
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Kveberg, Lise; Westgaard, Ingunn Hagen; Dai, Kezheng; Daws, Michael Rory; Fossum, Sigbjørn & Naper, Christian
[Vis alle 7 forfattere av denne artikkelen]
(2007).
The NKR-P1 family of receptors in rat recognizes C-type lectin related molecules.
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Inngjerdingen, Marit; Kveberg, Lise; Naper, Christian; Dai, Kezheng; Rolstad, Bent & Vaage, John Torgils
(2007).
Functional characterization of two major NK cell subsets in the rat, a Ly49+ and a NKR-P1C+ subset.
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Kveberg, Lise; Back, Camilla; Dai, KZD; Inngjerdingen, Marit; Rolstad, Bent & Ryan, JCR
[Vis alle 7 forfattere av denne artikkelen]
(2006).
The novel inhibitory NKR-P1C receptor and Ly49s3 identify two complementary, functionally distinct NK cell subsets in rats.
Tissue Antigens.
ISSN 0001-2815.
67,
s. 562–562.
Se alle arbeider i Cristin
Publisert
20. okt. 2014 12:45
- Sist endret
27. nov. 2023 14:04