Olav Klingenberg

Faglige interesser
Utredning av hemoglobinopatier, dvs. thalassemier og hemoglobinvarianter.
Proteinanalyser i klinisk diagnostikk.
Undervisning
PBL-undervisning i 5. semester.
Forelesninger, 6. semester: Anemi. Myelomatose og beslektede sykdommer.
Forelesninger, 3. modul: Plasmaproteiner. Analytisk koagulasjon. Myelomatose og andre gammopatier. Anemi. Inflammasjon/aktiv prosess.
Seminarer, 3. modul: Hemoglobinopatiutredning - jernmangel - anemi. Plasmaproteiner - M- komponent - inflammasjon. Laboratoriediagnostikk ved infeksjonssyksommer. Koagulasjon.
Klinikker, 3. modul: Hemostase - blødning og trombose.
Gruppeundervisning, 3. modul: Besøk i laboratoriet.
Bakgrunn
Fra 1/7-14: Overlege, Avdeling for medisinsk biokjemi, OUS og Førsteammanuensis II, Institutt for klinisk medisin, UiO
Fra 1/5-05: Overlege, Avdeling for medisinsk biokjemi, Rikshospitalet / OUS
2004: Spesialist i medisinsk biokjemi.
2001-2005: Assistentlege, Avdeling for medisinsk biokjemi, Ullevål
1999-2000: Postdoc, Biokjemisk avd., Inst. for kreftforskning, DNR
1999: Dr.med.,UiO, Biokjemisk avd., Inst. for kreftforskning, DNR
1988: Cand med., UiO
Verv
2008 - dd. - Redaksjonssekretær, Scandinavian Journal of Clinical and Laboratory Investigation
2011-2015 - Fagrepresentant i Helsedirektoratets faggruppe for Norsk laboratoriekodeverk
2005-2013 - Sekretær (4 år) og leder (4 år) i Norsk forening for medisinsk biokjemi
2004-2008 - Styremedlem og nestleder (1 år) i Norsk selskap for medisinsk biokjemi
Publikasjoner
- Holm, Are Martin; Andreassen, Siw Lillevik; Christensen, Vivi Lycke; Kongerud, Johny; Almås, Øystein; Auråen, Henrik; Henriksen, Anne Hildur; Aaberge, Ingeborg Aase S.; Klingenberg, Olav & Rustøen, Tone (2020). Hypogammaglobulinemia and risk of exacerbation and mortality in patients with COPD. The International Journal of Chronic Obstructive Pulmonary Disease. ISSN 1176-9106. 15, s 799- 807 . doi: 10.2147/COPD.S236656 Fulltekst i vitenarkiv.
- Grimholt, Runa Marie; Fjeld, Bente; Selsås, Hilde; Schwettmann, Lutz & Klingenberg, Olav (2019). Hb Aalesund (HBA2: c.400_406delAGCACCG), an Unstable α-Globin Variant Found in a Norwegian Patient Causing Moderate Hemolytic Anemia and Falsely High Hb A1c Using Ion Exchange High Performance Liquid Chromatography.. Hemoglobin. ISSN 0363-0269. 43(2), s 122- 125 . doi: 10.1080/03630269.2019.1614048 Fulltekst i vitenarkiv.
- Grimholt, Runa Marie; Harteveld, Cornelis; Arkesteijn, Sandra G J; Fjeld, Bente & Klingenberg, Olav (2018). Characterization of Two Deep Intronic Variants on the β-Globin Gene with Inconsistent Interpretations of Clinical Significance. Hemoglobin. ISSN 0363-0269. 42(2), s 126- 128 . doi: 10.1080/03630269.2018.1473255 Fulltekst i vitenarkiv.
- Grimholt, Runa Marie; Vestli, Anne; Urdal, Petter; Bechensteen, Anne Grete; Fjeld, Bente; Dalhus, Bjørn & Klingenberg, Olav (2018). Hb Oslo [β42(CD1)Phe→Ile; HBB: c.127T>A]: A novel unstable hemoglobin variant found in a Norwegian patient. Hemoglobin. ISSN 0363-0269. 42(2), s 78- 83 . doi: 10.1080/03630269.2018.1468773 Fulltekst i vitenarkiv.
- Klingenberg, Olav; Furuset, Torill; Hestbråten, Camilla Røising; Hallberg, Marit Hansen; Steiro, Astrid; Orset, Iren Røstbakken & Berg, Jens Petter (2017). HbA1c analysis by capillary electrophoresis?comparison with chromatography and an immunological method. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 77(6), s 458- 464 . doi: 10.1080/00365513.2017.1338747 Fulltekst i vitenarkiv.
- Sagedal, Solbjørg; Sandvik, Leiv; Klingenberg, Olav & Sandset, Per Morten (2017). β-Thromboglobulin may not reflect platelet activation during haemodialysis with the HeprAN membrane. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 77(8), s 679- 684 . doi: 10.1080/00365513.2017.1397288
- Berntsen, Natalie Lie; Klingenberg, Olav; Juran, Brian D.; Benito De Valle, Maria; Lindkvist, Björn; Lazaridis, Konstantinos N.; Boberg, Kirsten Muri; Karlsen, Tom Hemming & Hov, Johannes Espolin Roksund (2015). Association between HLA haplotypes and increased serum levels of IgG4 in patients with primary sclerosing cholangitis. Gastroenterology. ISSN 0016-5085. 148(5), s 924- 927.e2 . doi: 10.1053/j.gastro.2015.01.041
- Sudmann, Åshild Amelie; Piehler, Armin; Klingenberg, Olav & Urdal, Petter (2015). Six-day stability of erythrocyte and reticulocyte parameters in-vitro: A comparison of blood samples from healthy, iron-deficient, and thalassemic individuals. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 75(3), s 247- 253 . doi: 10.3109/00365513.2014.1000370
- Grimholt, Runa Marie; Urdal, Petter; Klingenberg, Olav & Piehler, Armin (2014). Rapid and reliable detection of alpha-globin copy number variations by quantitative real-time PCR. BMC Hematology. ISSN 2052-1839. . doi: 10.1186/2052-1839-14-4
- Urdal, Petter; Amundsen, Erik Koldberg; Toska, Karin & Klingenberg, Olav (2014). Automated alarm to detect antigen excess in serum free immunoglobulin light chain kappa and lambda assays. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 74(7), s 575- 581 . doi: 10.3109/00365513.2014.915426
- Bachmann-Harildstad, Gregor; Stenklev, Niels Chr.; Myrvoll, Elin Alise; Jablonski, Greg & Klingenberg, Olav (2011). Beta-Trace Protein as a Diagnostic Marker for Perilymphatic Fluid Fistula: A Prospective Controlled Pilot Study to Test a Sample Collection Technique. Otology & Neurotology. ISSN 1531-7129. 32(1), s 7- 10 . doi: 10.1097/MAO.0b013e3181fc74d0
- Henriksson, Carola Elisabeth; Hellum, Marit Synnøve; Haug, Kari Bente Foss; Aass, Hans Christian; Joø, Gun Brit; Øvstebø, Reidun; Trøseid, Anne-Marie Siebke; Klingenberg, Olav & Kierulf, Peter (2011). Anticoagulant effects of an antidiabetic drug on monocytes in vitro. Thrombosis Research. ISSN 0049-3848. 128(5), s E100- E106 . doi: 10.1016/j.thromres.2011.07.007
- Sagedal, Solbjørg; Witczak, Bartlomiej J; Osnes, Kåre; Hartmann, Anders; Os, Ingrid; Eikvar, Lars Kristian; Klingenberg, Olav & Brosstad, Frank Roger (2011). A Heparin-Coated Dialysis Filter (AN69 ST) Does Not Reduce Clotting during Hemodialysis when Compared to a Conventional Polysulfone Filter (F x 8). Blood Purification. ISSN 0253-5068. 32(3), s 151- 155 . doi: 10.1159/000325227
- Jensen, Torstein; Kierulf, Peter; Sandset, Per Morten; Klingenberg, Olav; Joø, Gun Brit; Godal, Hans Chr & Skjønsberg, Ole Henning (2007). Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from peripheral blood mononuclear cells. Thrombosis and Haemostasis. ISSN 0340-6245. 97(5), s 822- 829 . doi: 10.1160/TH07-01-0039 Vis sammendrag
- Fjeld, Bente; Sudmann-Day, Åshild Amelie; Grimholt, Runa Marie & Klingenberg, Olav (2019). Kan pasienten ha talassemi eller en hemoglobinvariant?. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 139(17) . doi: 10.4045/tidsskr.19.0121
- Grimholt, Runa Marie; Fjeld, Bente; Klingenberg, Olav & Piehler, Armin P (2017). Alfa-thalassemi på avveie – sjeldne former for alfa-thalassemi funnet hos norske pasienter. Vis sammendrag
- Grimholt, Runa Marie; Fjeld, Bente; Piehler, Armin & Klingenberg, Olav (2017). Chasing the Northern Light - (--)NOR and (αα) Aurora Borealis; two novel deletions causing alpha-thalassemia found in Norwegian patients.. Vis sammendrag
- Klingenberg, Olav (2017). Hemoglobin amino acids by the numbers. Scandinavian Journal of Clinical and Laboratory Investigation. ISSN 0036-5513. 77(1), s 1- 1 . doi: 10.1080/00365513.2017.1267428
- Grimholt, Runa Marie; Sudmann, Åshild Amelie; Piehler, Armin; Urdal, Petter & Klingenberg, Olav (2014). Hb Ullevaal [β78(EF2)Leu→Val; HBB: c.235C>G], a New Hemoglobin Variant Interfering with Hb A1c Measurement Using a Cation Exchange High Performance Liquid Chromatography Method. Hemoglobin. ISSN 0363-0269. 38(2), s 130- 132 . doi: 10.3109/03630269.2013.858640
- Hausken, Jon; Klingenberg, Olav; Mørkrid, Lars; Rollag, Halvor; Foss, Aksel & Midtvedt, Karsten (2012). Elevated Troponin I and NT-proBNP at the Time of Transplantation May Predict a Major Adverse Cardiac Event in the Early Postoperative Period After Renal Transplantation. Transplantation. ISSN 0041-1337. 94(2), s E15- E16 . doi: 10.1097/TP.0b013e31825b7633