Tom Hemming Karlsen

Professor - Forskningsleder KIT
Bilde av Tom Hemming Karlsen
English version of this page
Brukernavn
Besøksadresse Oslo universitetssykehus Rikshospitalet
Postadresse Postboks 4950 Nydalen OUS, Rikshospitalet 0424 Oslo

Bakgrunn

  • PhD Universitetet i Oslo, 2007
  • MD, Universitetet i Bergen, 1997

For mer informasjon, vennligst gå til Tom Hemming Karlsen's engelske presentasjon.

Publikasjoner

Thaventhiran JED, Lango Allen H, Burren OS et al. (2020) Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature 583:90-95. 

Ellinghaus D, Degenhardt F, Bujanda L et al. (2020) Genomewide Association Study of Severe Covid-19 with Respiratory Failure. New England Journal of Medicine 383:1522-1534.

Melum E, Jiang X, Baker KD, et al. (2019) Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nature Immunology, 20, 1644-1655.

Schneditz G, Elias JE, Pagano E, et al. (2019) GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump. Science Signaling, 562, eaau9048.

Manns MP, Burra P, Sargent J, Horton R, Karlsen TH (2018) The Lancet-EASL Commission on liver diseases in Europe: overcoming unmet needs, stigma, and inequities. Lancet, 10148, 621-622.

Sampaziotis F, Justin AW, Tysoe OC et al. (2017) Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids. Nature Medicine, 23, 954-963. 

Ji SG, Juran BD, Mucha S, et al. (2017) Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease. Nature Genetics, 49, 269-273.

Wang J, Thingholm LB, Skiecevièienë J, et al. (2016) Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota. Nature Genetics, 48,1396-1406.

Ellinghaus D, Jostins L, Spain SL, et al. (2016) Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics, 48, 510-8.

Sampaziotis F, Cardoso de Brito M, Madrigal P, et al. (2015) Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation. Nature Biotechnology, 33,845-52.

Goyette P, Boucher G, Mallon D, et al. (2015). High density mapping of the MHC reveals a common role for HLADRB1* 01:03 in IBD and heterozygous advantage in ulcerative colitis; Nature Genetics, 47 (2), 172-179.

Hirschfield GM, Karlsen TH, Lindor K, Adams D, (2013). Primary sclerosing cholangitisLancet, 382 (9904), 1587-99.

Liu JZ, Hov JR, Folseraas T, et al., (2013). Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis; Nature Genetics, 45 (6), 670-5.

Jostins L, Ripke S, Weersma RK, et al., (2012). Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease; Nature, 491 (7422), 119-24.

Anderson CA, Boucher G, Lees CW, et al., (2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47; Nature Genetics, 43 (3), 246-52.

Melum E, Franke A, Schramm C, et al., (2011). Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci; Nature Genetics, 43 (1), 17-9.

Ellinghaus E, Ellinghaus D, Stuart PE, et al., (2010). Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2; Nature Genetics, 42 (11), 991-5.

Franke A, Balschun T, Sina C, et al., (2010). Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL); Nature Genetics, 42 (4), 292-4.

Franke A, Balschun T, Karlsen TH, et al. (2008). Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility; Nature Genetics, 40 (11), 1319-23.

Franke A, Balschun T, Karlsen TH, et al. (2008). Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis; Nature Genetics, 40 (6), 713-5.

  • Hole, Mikal Jacob; Jørgensen, Kristin Kaasen; Holm, Kristian; Braadland, Peder Rustøen; Meyer-Myklestad, Malin Holm & Medhus, Asle Wilhelm [Vis alle 13 forfattere av denne artikkelen] (2022). A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation. Hepatology. ISSN 0270-9139. doi: 10.1002/hep.32773.
  • Braadland, Peder Rustøen; Schneider, Kai Markus; Bergquist, Annika; Molinaro, Antonio; Lövgren-Sandblom, Anita & Henricsson, Marcus [Vis alle 11 forfattere av denne artikkelen] (2022). Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis. JHEP Reports. 4(11), s. 1–10. doi: 10.1016/j.jhepr.2022.100561. Fulltekst i vitenarkiv
  • Chung, Brian K.; Øgaard, Jonas; Reims, Henrik Mikael; Karlsen, Tom Hemming & Melum, Espen (2022). Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis. Hepatology communications.. ISSN 2471-254X. 6(9), s. 2538–2550. doi: 10.1002/hep4.2001.
  • Graupera, Isabel; Thiele, Maja; Ma, Ann T.; Serra-Burriel, Miquel; Pich, Judit & Fabrellas, Núria [Vis alle 46 forfattere av denne artikkelen] (2022). LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries. BMC Public Health. ISSN 1471-2458. 22(1). doi: 10.1186/s12889-022-13724-6.
  • Degenhardt, Frauke; Ellinghaus, David; Juzenas, Simonas; Lerga-Jaso, Jon; Wendorff, Mareike & Maya-Miles, Douglas [Vis alle 50 forfattere av denne artikkelen] (2022). Detailed stratified GWAS analysis for severe COVID-19 in four European populations. Human Molecular Genetics. ISSN 0964-6906. s. 1–22. doi: 10.1093/hmg/ddac158. Fulltekst i vitenarkiv
  • Lei, Lin; Bruneau, Alix; El Mourabit, Haquima; Guégan, Justine; Folseraas, Trine & Lemoinne, Sara [Vis alle 18 forfattere av denne artikkelen] (2022). Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis. Hepatology. ISSN 0270-9139. doi: 10.1002/hep.32456.
  • Krag, Aleksander & Karlsen, Tom Hemming (2022). Er leversygdomme et overset problem i Europa? Ugeskrift for læger. ISSN 0041-5782. 184(4).
  • Valestrand, Laura Cecilie; Zheng, Fei; Hansen, Simen Hyll; Øgaard, Jonas; Hov, Johannes Espolin Roksund & Björkström, Niklas K. [Vis alle 9 forfattere av denne artikkelen] (2022). Bile from Patients with Primary Sclerosing Cholangitis Contains Mucosal-Associated Invariant T-Cell Antigens. American Journal of Pathology. ISSN 0002-9440. 192(4), s. 629–641. doi: 10.1016/j.ajpath.2021.12.008. Fulltekst i vitenarkiv
  • Hammer, Quirin; Dunst, Josefine; Christ, Wanda; Picarazzi, Francesca; Wendorff, Mareike & Momayyezi, Pouria [Vis alle 51 forfattere av denne artikkelen] (2022). SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells. Cell reports. ISSN 2211-1247. 38(10), s. 1–14. doi: 10.1016/j.celrep.2022.110503. Fulltekst i vitenarkiv
  • Uellendahl-Werth, Florian; Maj, Carlo; Borisov, Oleg; Juzenas, Simonas; Wacker, Eike Matthias & Jørgensen, Isabella Friis [Vis alle 21 forfattere av denne artikkelen] (2022). Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease. Communications Biology. ISSN 2399-3642. 5(1). doi: 10.1038/s42003-022-03031-6. Fulltekst i vitenarkiv
  • Karlsen, Tom Hemming (2022). Understanding COVID-19 through genome-wide association studies. Nature Genetics. ISSN 1061-4036. 54(4), s. 368–369. doi: 10.1038/s41588-021-00985-x.
  • Degenhardt, Frauke; Mayr, Gabriele; Wendorff, Mareike; Boucher, Gabrielle; Ellinghaus, Eva & Ellinghaus, David [Vis alle 51 forfattere av denne artikkelen] (2021). Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations. Human Molecular Genetics. ISSN 0964-6906. 30(5), s. 356–369. doi: 10.1093/hmg/ddab017. Fulltekst i vitenarkiv
  • Reich, Maria; Spomer, Lina; Klindt, Caroline; Fuchs, Katharina; Stindt, Jan & Deutschmann, Kathleen [Vis alle 33 forfattere av denne artikkelen] (2021). Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis. Journal of Hepatology. ISSN 0168-8278. 75(3), s. 634–646. doi: 10.1016/j.jhep.2021.03.029. Fulltekst i vitenarkiv
  • Karlsen, Tom Hemming; Sheron, Nick; Zelber-Sagi, Shira; Carrieri, Patrizia; Dusheiko, Geoffery & Bugianesi, Elisabetta [Vis alle 57 forfattere av denne artikkelen] (2021). The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality. The Lancet. ISSN 0140-6736. doi: 10.1016/S0140-6736%2821%2901701-3. Fulltekst i vitenarkiv
  • Nakanishi, Tomoko; Pigazzini, Sara; Degenhardt, Frauke; Cordioli, Mattia; Butler-Laporte, Guillaume & Maya-Miles, Douglas [Vis alle 47 forfattere av denne artikkelen] (2021). Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Journal of Clinical Investigation. ISSN 0021-9738. 131(23). doi: 10.1172/JCI152386.
  • Pagano, Ester; Elias, Joshua E.; Schneditz, Georg Thomas; Saveljeva, Svetlana; Holland, Lorraine M. & Borrelli, Francesca [Vis alle 9 forfattere av denne artikkelen] (2021). Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment. Gut. ISSN 0017-5749. doi: 10.1136/gutjnl-2020-323363. Fulltekst i vitenarkiv
  • Fossdal, Guri; Mjelle, Anders Batman; Wiencke, Kristine; Bjørk, Ida Torunn; Gilja, Odd Helge & Folseraas, Trine [Vis alle 10 forfattere av denne artikkelen] (2021). Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF. JHEP Reports. 3(5), s. 1–10. doi: 10.1016/j.jhepr.2021.100328. Fulltekst i vitenarkiv
  • Zheng, Thenghao; Ellinghaus, David; Juzenas, Simonas; Cossais, François; Burmeister, Greta & Mayr, Gabriele [Vis alle 86 forfattere av denne artikkelen] (2021). Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease. Gut. ISSN 0017-5749. 70(8), s. 1538–1549. doi: 10.1136/gutjnl-2020-323868. Fulltekst i vitenarkiv
  • Vedeld, Hege Marie; Grimsrud, Marit Mæhle; Andresen, Kim; Pharo, Heidi Dietrichson; von Seth, Erik & Karlsen, Tom Hemming [Vis alle 15 forfattere av denne artikkelen] (2021). Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile. Hepatology. ISSN 0270-9139. doi: 10.1002/hep.32125. Fulltekst i vitenarkiv
  • Niemi, Mari E.K.; Karjalainen, Juha; Liao, Rachel G.; Neale, Benjamin M.; Daly, Mark & Ganna, Andrea [Vis alle 84 forfattere av denne artikkelen] (2021). Mapping the human genetic architecture of COVID-19. Nature. ISSN 0028-0836. 600(7889), s. 472–477. doi: 10.1038/s41586-021-03767-x. Fulltekst i vitenarkiv
  • Schneider, Kai Markus; Candels, Lena Susanna; Hov, Johannes R.; Myllys, Maiju; Hassan, Reham & Schneider, Carolin Victoria [Vis alle 26 forfattere av denne artikkelen] (2021). Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling. Nature Metabolism. 3(9), s. 1228–1241. doi: 10.1038/s42255-021-00452-1.
  • Jiang, Xiaojun; Bergquist, Annika; Löscher, Britt-Sabina; Venkatesh, Geetha; Mold, Jeff E. & Holm, Kristian [Vis alle 15 forfattere av denne artikkelen] (2021). A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis. Science Translational Medicine. ISSN 1946-6234. 13(582). doi: 10.1126/scitranslmed.abb0036.
  • Bossen, Lars; Vesterhus, Mette Nåmdal; Hov, Johannes Espolin Roksund; Färkkilä, Martti; Rosenberg, William & Møller, Holger J. [Vis alle 9 forfattere av denne artikkelen] (2021). Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis. Clinical and Translational Gastroenterology. ISSN 2155-384X. 12(3), s. e00315–e00315. doi: 10.14309/ctg.0000000000000315. Fulltekst i vitenarkiv
  • Dhillon, Amandeep Kaur; Rupp, Christian; Bergquist, Annika; Voitl, Robert; Folseraas, Trine & Trøseid, Marius [Vis alle 12 forfattere av denne artikkelen] (2021). Associations of neopterin and kynurenine–tryptophan ratio with survival in primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 56(4), s. 443–452. doi: 10.1080/00365521.2021.1880627. Fulltekst i vitenarkiv
  • Vesterhus, Mette; Nielsen, Mette Juul; Hov, Johannes Roksund; Saffioti, Francesca; Manon-Jensen, Tina & Leeming, Diana Julie [Vis alle 12 forfattere av denne artikkelen] (2021). Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease. JHEP Reports. 3(1), s. 1–11. doi: 10.1016/j.jhepr.2020.100178. Fulltekst i vitenarkiv
  • Ellinghaus, David; Degenhardt, Frauke; Bujanda, Luis; Buti, Maria; Abillios, Agustin & Invernizzi, Pietro [Vis alle 30 forfattere av denne artikkelen] (2020). Genomewide Association Study of Severe Covid-19 with Respiratory Failure. New England Journal of Medicine. ISSN 0028-4793. doi: 10.1056/NEJMoa2020283.
  • Thaventhiran, James; Allen, Hana Lango; Burren, Oliver S; Rae, William; Greene, Daniel & Staples, Emily [Vis alle 50 forfattere av denne artikkelen] (2020). Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. ISSN 0028-0836. 583(7814), s. 90–95. doi: 10.1038/s41586-020-2265-1. Fulltekst i vitenarkiv
  • Lapitz, Ainhoa; Arbelaiz, Ander; O'Rourke, Colm J; Lavin, José L.; Casta, Adelaida La & Ibarra, Cesar [Vis alle 26 forfattere av denne artikkelen] (2020). Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis. Cells. ISSN 2073-4409. 9(3). doi: 10.3390/cells9030721..
  • Mousa, Omar Y; Juran, Brian D; McCauley, Bryan M.; Vesterhus, Mette; Folseraas, Trine & Turgeon, Coleman T. [Vis alle 19 forfattere av denne artikkelen] (2020). Bile Acid Profiles in Primary Sclerosing Cholangitis and their Ability to Predict Hepatic Decompensation. Hepatology. ISSN 0270-9139. doi: 10.1002/hep.31652. Fulltekst i vitenarkiv
  • Kummen, Martin; Thingholm, Louise B.; Rühlemann, Malte C.; Holm, Kristian; Hansen, Simen Hyll & Moitinho-Silva, Lucas [Vis alle 22 forfattere av denne artikkelen] (2020). Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis. Gastroenterology. ISSN 0016-5085. doi: 10.1053/j.gastro.2020.12.058. Fulltekst i vitenarkiv
  • Deeb, Maya; Karlsen, Tom Hemming & Hirschfield, Gideon M. (2020). The 6 C's of primary sclerosing cholangitis. Journal of Hepatology. ISSN 0168-8278. 73(5), s. 1255–1256. doi: 10.1016/j.jhep.2020.06.033.
  • Valestrand, Laura Cecilie; Berntsen, Natalie Lie; Fei, Zheng; Schrumpf, Erik; Hansen, Simen Hyll & Karlsen, Tom Hemming [Vis alle 10 forfattere av denne artikkelen] (2020). Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells. Clinical and Experimental Immunology. ISSN 0009-9104. doi: 10.1111/cei.13541. Fulltekst i vitenarkiv
  • Goeppert, Benjamin; Folseraas, Trine; Roessler, Stephanie; Kloor, Matthias; Volckmar, Anna-Lena & Endris, Volker [Vis alle 36 forfattere av denne artikkelen] (2020). Genomic characterization of cholangiocarcinoma in primary sclerosing cholangitis reveals therapeutic opportunities. Hepatology. ISSN 0270-9139. 72(4), s. 1253–1266. doi: 10.1002/hep.31110. Fulltekst i vitenarkiv
  • Lohse, Ansgar W.; Sebode, Marcial; Jørgensen, Marianne H.; Ytting, Henriette; Karlsen, Tom Hemming & Kelly, Deirdre [Vis alle 8 forfattere av denne artikkelen] (2020). Second-line and third-line therapy for autoimmune hepatitis: A position statement from the European Reference Network on Hepatological Diseases and the International Autoimmune Hepatitis Group. Journal of Hepatology. ISSN 0168-8278. s. 1–12. doi: 10.1016/j.jhep.2020.07.023. Fulltekst i vitenarkiv
  • Kummen, Martin; Solberg, Ole Geir; Larsen, Christopher Storm; Holm, Kristian; Ragnarsson, Asgrimur & Trøseid, Marius [Vis alle 18 forfattere av denne artikkelen] (2020). Rosuvastatin alters the genetic composition of the human gut microbiome. Scientific Reports. ISSN 2045-2322. 10:5397, s. 1–9. doi: 10.1038/s41598-020-62261-y. Fulltekst i vitenarkiv
  • Vesterhus, Mette & Karlsen, Tom Hemming (2020). Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities. Journal of gastroenterology. ISSN 0944-1174. 55, s. 588–614. doi: 10.1007/s00535-020-01681-z. Fulltekst i vitenarkiv
  • Melum, Espen; Jiang, Xiaojun; Baker, Kirsti B; Macedo, M Fatima; Fritsch, Jürgen & Dowds, C Marie [Vis alle 21 forfattere av denne artikkelen] (2019). Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. Nature Immunology. ISSN 1529-2908. 20(12), s. 1644–1655. doi: 10.1038/s41590-019-0504-0. Fulltekst i vitenarkiv
  • Rühlemann, Malte C.; Liwinski, Timur; Heinsen, Femke-Anouska; Bang, Corinna; Zenouzi, Roman & Kummen, Martin [Vis alle 17 forfattere av denne artikkelen] (2019). Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis. Alimentary Pharmacology and Therapeutics. ISSN 0269-2813. 50(5), s. 580–589. doi: 10.1111/apt.15375. Fulltekst i vitenarkiv
  • Liwinski, Timur; Zenouzi, Roman; John, Clara; Ehlken, Hanno; Rühlemann, Malte C. & Bang, Corinna [Vis alle 18 forfattere av denne artikkelen] (2019). Alterations of the bile microbiome in primary sclerosing cholangitis. Gut. ISSN 0017-5749. s. 1–8. doi: 10.1136/gutjnl-2019-318416. Fulltekst i vitenarkiv
  • Thingholm, Louise B.; Rühlemann, Malte C.; Koch, Manja; Fuqua, Brie; Laucke, Guido & Böhm, Ruwen [Vis alle 25 forfattere av denne artikkelen] (2019). Obese individuals with and without type 2 diabetes show different gut microbial functional capacity and composition. Cell Host and Microbe. ISSN 1931-3128. 26(2), s. 252–264.e10. doi: 10.1016/j.chom.2019.07.004.
  • Dhillon, Amandeep Kaur; Kremer, Andreas E.; Kummen, Martin; Boberg, Kirsten Muri; Elferink, Ronald P. Oude & Karlsen, Tom Hemming [Vis alle 9 forfattere av denne artikkelen] (2019). Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis. Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-44762-7. Fulltekst i vitenarkiv
  • Banales, Jesus M.; Huebert, Robert C.; Karlsen, Tom Hemming; Strazzabosco, Mario; LaRusso, Nicholas F. & Gores, Gregory J. (2019). Cholangiocyte pathobiology. Nature reviews: Gastroenterology & hepatology. ISSN 1759-5045. 16(5), s. 269–281. doi: 10.1038/s41575-019-0125-y. Fulltekst i vitenarkiv
  • Schneditz, Georg Thomas; Elias, Joshua E.; Pagano, Ester; Cader, M. Zaeem; Saveljeva, Svetlana & Long, Kathleen [Vis alle 14 forfattere av denne artikkelen] (2019). GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump. Science Signaling. ISSN 1945-0877. 12:eaau9048(562), s. 1–20. doi: 10.1126/scisignal.aau9048. Fulltekst i vitenarkiv
  • Jørgensen, Silje Fjellgård; Macpherson, Magnhild Eide; Bjørnetrø, Tonje; Holm, Kristian; Kummen, Martin & Rashidi, Azita [Vis alle 18 forfattere av denne artikkelen] (2019). Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency. Scientific Reports. ISSN 2045-2322. 9:167, s. 1–10. doi: 10.1038/s41598-018-35367-7. Fulltekst i vitenarkiv
  • Dhillon, Amandeep Kaur; Kummen, Martin; Trøseid, Marius; Åkra, Sissel; Liaskou, Evaggelia & Moum, Bjørn [Vis alle 10 forfattere av denne artikkelen] (2019). Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis. Liver international (Print). ISSN 1478-3223. 39(2), s. 371–381. doi: 10.1111/liv.13979. Fulltekst i vitenarkiv
  • Nielsen, MJ; Thorburn, Douglas; Leeming, DJ; Hov, Johannes Espolin Roksund; Nygård, Ståle & Moum, Bjørn [Vis alle 15 forfattere av denne artikkelen] (2018). Serological markers of extracellular matrix remodeling predict transplant-free survival in primary sclerosing cholangitis. Alimentary Pharmacology and Therapeutics. ISSN 0269-2813. 48, s. 179–189. doi: 10.1111/apt.14806.
  • Goode, EC; Clark, AB; Melis, GM; Srivastava, B; Spiess, K & Gelson, WTH [Vis alle 24 forfattere av denne artikkelen] (2018). Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System. Hepatology. ISSN 0270-9139. 69(5), s. 2120–2135. doi: 10.1002/hep.30479. Fulltekst i vitenarkiv
  • Carpino, Guido; Cardinale, Vincenzo; Folseraas, Trine; Overi, Diletta; Grzyb, Krzysztof & Constantini, David [Vis alle 11 forfattere av denne artikkelen] (2018). Neoplastic Transformation of the Peribiliary Stem Cell Niche in Cholangiocarcinoma Arisen in Primary Sclerosing Cholangitis. Hepatology. ISSN 0270-9139. 69(2), s. 622–638. doi: 10.1002/hep.30210. Fulltekst i vitenarkiv
  • Chung, Brian Kai-Ho; Henriksen, Eva Kristine Klemsdal; Jørgensen, Kristin Kaasen; Karlsen, Tom Hemming; Hirschfield, Gideon & Liaskou, Evaggelia (2018). Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease. Hepatology communications.. ISSN 2471-254X. 2(8), s. 960–971. doi: 10.1002/hep4.1200. Fulltekst i vitenarkiv
  • Eaton, JE; Vesterhus, Mette; McCauley, Bryan M.; Atkinson, EJ; Schlicht, EM & Juran, BD [Vis alle 11 forfattere av denne artikkelen] (2018). Primary sclerosing cholangitis risk estimate tool (PREsTo) predicts outcomes of the disease: A derivation and validation study using machine learning. Hepatology. ISSN 0270-9139. s. 1–11. doi: 10.1002/hep.30085.
  • Tronstad, Rune Rose; Polushina, Tatiana; Brattbakk, Hans-Richard; Stansberg, Christine; Volkmann, Hilde Løland Von & Hanevik, Kurt [Vis alle 19 forfattere av denne artikkelen] (2018). Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 53(10-11), s. 1264–1273. doi: 10.1080/00365521.2018.1521867.
  • Cornberg, Markus; Tacke, Frank & Karlsen, Tom Hemming (2018). Clinical Practice Guidelines of the European Association for the study of the Liver – Advancing methodology but preserving practicability. Journal of Hepatology. ISSN 0168-8278. s. 1–3. doi: 10.1016/j.jhep.2018.10.011.
  • Åberg, Fredrik; Isoniemi, Helena; Pukkala, Eero; Jalanko, Hannu; Rasmussen, Allan & Storm, Hans H. [Vis alle 17 forfattere av denne artikkelen] (2018). Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries. Liver transplantation. ISSN 1527-6465. 24(9), s. 1252–1259. doi: 10.1002/lt.25305. Fulltekst i vitenarkiv
  • Berntsen, Natalie Lie; Fosby, Bjarte; Tan, Corey; Reims, Henrik Mikael; Øgaard, Jonas & Jiang, Xiaojun [Vis alle 12 forfattere av denne artikkelen] (2018). Natural killer T cells mediate inflammation in the bile ducts. Mucosal Immunology. ISSN 1933-0219. s. 1–9. doi: 10.1038/s41385-018-0066-8.
  • Momozawa, Yukihide; Dmitrieva, Julia; Théâtre, Emilie; Deffontaine, Valérie; Rahmouni, Souad & Charloteaux, Benoît [Vis alle 36 forfattere av denne artikkelen] (2018). IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. Nature Communications. ISSN 2041-1723. 9:2427, s. 1–18. doi: 10.1038/s41467-018-04365-8.
  • Pollheimer, Marion J.; Racedo, Silvia; Mikels-Vigdal, Amanda; Marshall, Derek; Bowlus, Christopher & Lackner, Carolin [Vis alle 21 forfattere av denne artikkelen] (2018). Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis. Journal of Hepatology. ISSN 0168-8278. 69(2), s. 368–377. doi: 10.1016/j.jhep.2018.04.009.
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  • Hov, Johannes Espolin Roksund & Karlsen, Tom Hemming (2017). The Microbiome in Primary Sclerosing Cholangitis: Current Evidence and Potential Concepts. Seminars in liver disease (Print). ISSN 0272-8087. 37(4), s. 314–331. doi: 10.1055/s-0037-1608801. Fulltekst i vitenarkiv
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  • Carpino, Guido; Cardinale, Vincenzo; Folseraas, Trine; Overi, D; Floreani, A & Franchitto, Antonio [Vis alle 12 forfattere av denne artikkelen] (2017). Hepatic stem/progenitor cell activation differs between primary sclerosing and primary biliary cholangitis. American Journal of Pathology. ISSN 0002-9440. 188(3), s. 627–639. doi: 10.1016/j.ajpath.2017.11.010.
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  • O'Hara, Steven P; Karlsen, Tom Hemming & LaRusso, Nicholas F. (2017). Cholangiocytes and the environment in primary sclerosing cholangitis: Where is the link? Gut. ISSN 0017-5749. 66(11), s. 1873–1877. doi: 10.1136/gutjnl-2017-314249.
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  • Vesterhus, Mette; Holm, Anders; Hov, Johannes Espolin Roksund; Nygård, Ståle; Schrumpf, Erik & Melum, Espen [Vis alle 23 forfattere av denne artikkelen] (2017). Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis. Journal of Hepatology. ISSN 0168-8278. 66(6), s. 1214–1222. doi: 10.1016/j.jhep.2017.01.019.
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  • Jiang, Xiaojun & Karlsen, Tom Hemming (2017). Genetics of primary sclerosing cholangitis and pathophysiological implications. Nature reviews: Gastroenterology & hepatology. ISSN 1759-5045. 14(5), s. 279–295. doi: 10.1038/nrgastro.2016.154.
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  • Hov, Johannes Espolin Roksund; Boberg, Kirsten Muri; Taraldsrud, Eli; Vesterhus, Mette; Boyadzhieva, Maria & Solberg, Inger Camilla [Vis alle 11 forfattere av denne artikkelen] (2017). Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis. Liver international (Print). ISSN 1478-3223. 37(3), s. 458–465. doi: 10.1111/liv.13238.
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  • Thaventhiran, James E. D.; Lango Allen, Hana; Burren, Oliver S.; Rae, William; Greene, Daniel & Staples, Emily [Vis alle 632 forfattere av denne artikkelen] (2020). Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort (Nature, (2020), 583, 7814, (90-95), 10.1038/s41586-020-2265-1). Nature. ISSN 0028-0836. 584(7819). doi: 10.1038/s41586-020-2556-6.
  • Borgstrøm, Reidar; Karlsen, Tom Hemming & Lundin, Knut Erik Aslaksen (2019). Er årets villreinkvote på Hardangervidda en ny standard i norsk viltforvaltning? Nationen. ISSN 0805-3782.
  • Reimers, Eigil; Borgstrøm, Reidar; Hjeljord, Olav; Lundin, Knut Erik Aslaksen & Karlsen, Tom Hemming (2019). Faglig uforsvarlig tiltak mot skrantesyke. Dagens næringsliv. ISSN 0803-9372.
  • Karlsen, Tom Hemming & Newsome, Phil N (2019). The dawn of a new EASL – A new chapter in the history of the European Association for the Study of the liver. Journal of Hepatology. ISSN 0168-8278. 71(1), s. 5–8. doi: 10.1016/j.jhep.2019.03.010.
  • Colombo, Massimo & Karlsen, Tom Hemming (2018). The EASL International Liver Foundation: A growing pup with missions that are distinct yet integrated with those of its mother. Journal of Hepatology. ISSN 0168-8278. doi: 10.1016/j.jhep.2018.11.017.
  • Karlsen, Tom Hemming & Tacke, Frank (2018). <The times they are a'changin?> ? Positioning the European Association for the Study of the Liver in the changing landscape of hepatology. Journal of Hepatology. ISSN 0168-8278. 68(5), s. 873–875. doi: 10.1016/j.jhep.2018.02.001.
  • Karlsen, Tom Hemming & Hirschfield, Gideon M. (2016). Genetics of Primary Sclerosing Cholangitis. I Forman, Lisa (Red.), Primary Sclerosing Cholangitis. Current Understanding, Management, and Future Developments. Springer. ISSN 978-3-319-40906-1. s. 99–110. doi: 10.1007/978-3-319-40908-5_8.
  • Jørgensen, Silje Fjellgård; Macpherson, Magnhild E; Bjøro, Kristian; Karlsen, Tom Hemming; Reims, Henrik Mikael & Grzyb, Krzysztof [Vis alle 10 forfattere av denne artikkelen] (2016). Liver transplantation in patients with primary antibody deficiency. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. doi: 10.1016/j.jaci.2016.10.025.
  • Tronstad, Rune Rose; Fiskerstrand, Torunn; Karlsen, Tom Hemming; Knappskog, Per & Le Hellard, Stephanie (2019). Clinical and molecular effects of guanylate cyclase C-activation. Universitetet i Bergen. ISSN 9788230854426.

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Publisert 25. nov. 2014 13:07 - Sist endret 23. aug. 2022 19:37