Magnus Løberg

• Juul, Frederik Emil; Cross, Amanda J.; Schoen, Robert E.; Senore, Carlo; Pinsky, Paul F. & Miller, Eric A. [Show all 17 contributors for this article] (2024). Effectiveness of Colonoscopy Screening vs Sigmoidoscopy Screening in Colorectal Cancer. JAMA Network Open. ISSN 2574-3805. 7(2). doi: 10.1001/jamanetworkopen.2024.0007. Show summary

  Importance: Randomized clinical screening trials have shown that sigmoidoscopy screening reduces colorectal cancer (CRC) incidence and mortality. Colonoscopy has largely replaced sigmoidoscopy for CRC screening, but long-term results from randomized trials on colonoscopy screening are still lacking. Objective: To estimate the additional screening benefit of colonoscopy compared with sigmoidoscopy. Design, setting, and participants: This comparative effectiveness simulation study pooled data on 358 204 men and women randomly assigned to sigmoidoscopy screening or usual care in 4 randomized sigmoidoscopy screening trials conducted in Norway, Italy, the US, and UK with inclusion periods in the years 1993 to 2001. The primary analysis of the study was conducted from January 19 to December 30, 2021. Intervention: Invitation to endoscopic screening. Main outcomes and measures: Primary outcomes were CRC incidence and mortality. Using pooled 15-year follow-up data, colonoscopy screening effectiveness was estimated assuming that the efficacy of colonoscopy in the proximal colon was similar to that observed in the distal colon in the sigmoidoscopy screening trials. The simulation model was validated using data from Norwegian participants in a colonoscopy screening trial. Results: This analysis included 358 204 individuals (181 971 women [51%]) aged 55 to 64 years at inclusion with a median follow-up time ranging from 15 to 17 years. Compared with usual care, colonoscopy prevented an estimated 50 (95% CI, 42-58) CRC cases per 100 000 person-years, corresponding to 30% incidence reduction (rate ratio, 0.70 [95% CI, 0.66-0.75]), and prevented an estimated 15 (95% CI, 11-19) CRC deaths per 100 000 person-years, corresponding to 32% mortality reduction (rate ratio, 0.68 [95% CI, 0.61-0.76]). The additional benefit of colonoscopy screening compared with sigmoidoscopy was 12 (95% CI, 10-14) fewer CRC cases and 4 (95% CI, 3-5) fewer CRC deaths per 100 000 person-years, corresponding to percentage point reductions of 6.9 (95% CI, 6.0-7.9) for CRC incidence and 7.6 (95% CI, 5.7-9.6) for CRC mortality. The number needed to switch from sigmoidoscopy to colonoscopy screening was 560 (95% CI, 486-661) to prevent 1 CRC case and 1611 (95% CI, 1275-2188) to prevent 1 CRC death. Conclusions and relevance: The findings of this comparative effectiveness study assessing long-term follow-up after CRC screening suggest that there was an additional preventive effect on CRC incidence and mortality associated with colonoscopy screening compared with sigmoidoscopy screening, but the additional preventive effect was less than what was achieved by introducing sigmoidoscopy screening where no screening existed. The results probably represent the upper limit of what may be achieved with colonoscopy screening compared with sigmoidoscopy screening.

• Bretthauer, Michael; Wieszczy, Paulina; Løberg, Magnus; Kamiński, Michał Filip; Werner, Tarjei Fiskergård & Helsingen, Lise Mørkved [Show all 10 contributors for this article] (2023). Estimated Lifetime Gained with Cancer Screening Tests: A Meta-Analysis of Randomized Clinical Trials. JAMA Internal Medicine. ISSN 2168-6106. 183(11), p. 1196–1203. doi: 10.1001/jamainternmed.2023.3798.
• Jodal, Henriette C.; Akwiwu, Eddymurphy U.; Lemmens, Margriet; Delis-van Diemen, Pien M; Klotz, Dagmar & Leon, Leticia G [Show all 17 contributors for this article] (2023). Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case-Control Study. Cancer Research Communications. ISSN 2767-9764. 3(13), p. 2292–2301. doi: 10.1158/2767-9764.CRC-23-0186.
• Jodal, Henriette C.; Wieszczy, Paulina; Klotz, Dagmar; Herfindal, Magnhild; Barua, Ishita & Tag, Petter [Show all 13 contributors for this article] (2023). A Comparison of Risk Classification Systems of Colorectal Adenomas: A Case-Cohort Study. Gastroenterology. ISSN 0016-5085. 165, p. 483–491. doi: 10.1053/j.gastro.2023.04.028. Full text in Research Archive
• Holme, Øyvind; Kalager, Mette; Bretthauer, Michael; Adami, Hans Olov; Helsingen, Lise Mørkved & Løberg, Magnus (2023). Ongoing Trials Will Not Determine the Comparative Effectiveness of Colorectal Cancer Screening Tests. Gastroenterology. ISSN 0016-5085. 164(6), p. 856–860. doi: 10.1053/j.gastro.2020.02.071.
• Yu, Jingru; Refsum, Erle; Wieszczy, Paulina; Helsingen, Lise Mørkved; Perrin, Vera & Högdén, Amanda [Show all 12 contributors for this article] (2023). Risk of malignant lymphomas in patients with inflammatory bowel disease: a population-based cohort study. BMJ open gastroenterology. ISSN 2054-4774. 10(1). doi: 10.1136/bmjgast-2022-001037.
• Tønnesen, Christer Julseth; Hjelmesæth, Jøran Sture; Aabakken, Lars; Lund, Randi Størdal; Johnson, Line Kristin & Hertel, Jens Kristoffer [Show all 9 contributors for this article] (2023). A pilot study of implementation of endoscopic sleeve gastroplasty (ESG) in Norway. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 58(10), p. 1180–1184. doi: 10.1080/00365521.2023.2204389. Full text in Research Archive Show summary

  Bariatric surgery is the most effective treatment for obesity but is invasive and associated with serious complications. Endoscopic sleeve gastroplasty (ESG) is a less invasive weight loss procedure to reduce the stomach volume by full-thickness sutures. ESG has been adopted in many countries, but implementation at Scandinavian centres has not yet been documented. We performed a clinical pilot trial at a Norwegian centre with the primary objective to assess the feasibility of the ESG procedure. Patients and methods We included the first 10 patients treated with ESG at a Norwegian centre in a single-arm pilot study. The eligibility criteria were either a body mass index (BMI) of 40–49.9 kg/m2, BMI 35–39.9 kg/m2 and at least one obesity-related comorbidity, or BMI 30–34.9 kg/m2 and type 2 diabetes. Patient follow-up resembled the scheme used for bariatric surgery at the center, including dietary plans and outpatient visits. Results All procedures were technically successful except for one patient who had adhesions between the stomach and anterior abdominal wall, related to a prior hernia repair, resulting in less-than-intended stomach volume reduction. Mean total body weight loss (TBWL) after 26 and 52 weeks was 12.2% (95% CI 8.1–16.2) and 9.1% (95% CI 3.3 − 15.0). One patient experienced a minor suture-induced diaphragmatic injury, which was successfully managed conservatively. Conclusions This first Scandinavian clinical trial of ESG, documenting the implementation of the procedure at a Norwegian center, demonstrated acceptable feasibility and safety, with large variations in individual weight loss during the 52-week follow-up period.

• Mori, Yuichi; Wang, Pu; Løberg, Magnus; Misawa, Masashi; Repici, Alessandro & Spadaccini, Marco [Show all 26 contributors for this article] (2022). Impact of Artificial Intelligence on Colonoscopy Surveillance After Polyp Removal: A Pooled Analysis of Randomized Trials. Clinical Gastroenterology and Hepatology. ISSN 1542-3565. doi: 10.1016/j.cgh.2022.08.022. Full text in Research Archive Show summary

  Background and Aims Artificial intelligence (AI) tools aimed at improving polyp detection have been shown to increase the adenoma detection rate during colonoscopy. However, it is unknown how increased polyp detection rates by AI affect the burden of patient surveillance after polyp removal. Methods We conducted a pooled analysis of 9 randomized controlled trials (5 in China, 2 in Italy, 1 in Japan, and 1 in the United States) comparing colonoscopy with or without AI detection aids. The primary outcome was the proportion of patients recommended to undergo intensive surveillance (ie, 3-year interval). We analyzed intervals for AI and non-AI colonoscopies for the U.S. and European recommendations separately. We estimated proportions by calculating relative risks using the Mantel-Haenszel method. Results A total of 5796 patients (51% male, mean 53 years of age) were included; 2894 underwent AI-assisted colonoscopy and 2902 non-AI colonoscopy. When following U.S. guidelines, the proportion of patients recommended intensive surveillance increased from 8.4% (95% CI, 7.4%–9.5%) in the non-AI group to 11.3% (95% CI, 10.2%–12.6%) in the AI group (absolute difference, 2.9% [95% CI, 1.4%–4.4%]; risk ratio, 1.35 [95% CI, 1.16–1.57]). When following European guidelines, it increased from 6.1% (95% CI, 5.3%–7.0%) to 7.4% (95% CI, 6.5%–8.4%) (absolute difference, 1.3% [95% CI, 0.01%–2.6%]; risk ratio, 1.22 [95% CI, 1.01–1.47]). Conclusions The use of AI during colonoscopy increased the proportion of patients requiring intensive colonoscopy surveillance by approximately 35% in the United States and 20% in Europe (absolute increases of 2.9% and 1.3%, respectively). While this may contribute to improved cancer prevention, it significantly adds patient burden and healthcare costs.

• Barua, Ishita; Misawa, Masashi; Glissen Brown, Jeremy R.; Walradt, Trent; Kudo, Shin-ei & Sheth, Sunil G. [Show all 19 contributors for this article] (2022). Speedometer for withdrawal time monitoring during colonoscopy: a clinical implementation trial. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. doi: 10.1080/00365521.2022.2154616.
• Juul, Frederik Emil; Garborg, Kjetil Kjeldstad; Nesbakken, Philip Eugen; Løberg, Magnus; Wieszczy, Paulina & Cubiella, Joaquín [Show all 19 contributors for this article] (2022). Rates of repeated colonoscopies to clean the colon from low-risk and high-risk adenomas: Results from the EPoS trials. Gut. ISSN 0017-5749. doi: 10.1136/gutjnl-2022-327696. Full text in Research Archive Show summary

  Objective High-quality colonoscopy (adequate bowel preparation, whole-colon visualisation and removal of all neoplastic polyps) is a prerequisite to start polyp surveillance, and is ideally achieved in one colonoscopy. In a large multinational polyp surveillance trial, we aimed to investigate clinical practice variation in number of colonoscopies needed to enrol patients with low-risk and high-risk adenomas in polyp surveillance. Design We retrieved data of all patients with low-risk adenomas (one or two tubular adenomas <10 mm with low-grade dysplasia) and high-risk adenomas (3–10 adenomas, ≥1 adenoma ≥10 mm, high-grade dysplasia or villous components) in the European Polyp Surveillance trials fulfilling certain logistic and methodologic criteria. We analysed variations in number of colonoscopies needed to achieve high-quality colonoscopy and enter polyp surveillance by endoscopy centre, and by endoscopists who enrolled ≥30 patients. Results The study comprised 15 581 patients from 38 endoscopy centres in five European countries; 6794 patients had low-risk and 8787 had high-risk adenomas. 961 patients (6.2%, 95% CI 5.8% to 6.6%) underwent two or more colonoscopies before surveillance began; 101 (1.5%, 95% CI 1.2% to 1.8%) in the low-risk group and 860 (9.8%, 95% CI 9.2% to 10.4%) in the high-risk group. Main reasons were poor bowel preparation (21.3%) or incomplete colonoscopy/polypectomy (14.4%) or planned second procedure (27.8%). Need of repeat colonoscopy varied between study centres ranging from 0% to 11.8% in low-risk adenoma patients and from 0% to 63.9% in high-risk adenoma patients. On the second colonoscopy, the two most common reasons for a repeat (third) colonoscopy were piecemeal resection (26.5%) and unspecified reason (23.9%). Conclusion There is considerable practice variation in the number of colonoscopies performed to achieve complete polyp removal, indicating need for targeted quality improvement to reduce patient burden. Trial registration number NCT02319928.

• Ribe, Sara Gunnestad; Botteri, Edoardo; Løberg, Magnus; Randel, Kristin Ranheim; Kalager, Mette & Nilsen, Jens Aksel [Show all 8 contributors for this article] (2022). Impact of time between faecal immunochemical tests in colorectal cancer screening on screening results: A natural experiment. International Journal of Cancer. ISSN 0020-7136. doi: 10.1002/ijc.34351.
• Bretthauer, Michael; Løberg, Magnus; Wieszczy, Paulina; Kalager, Mette; Emilsson, Louise & Garborg, Kjetil Kjeldstad [Show all 21 contributors for this article] (2022). Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death. New England Journal of Medicine. ISSN 0028-4793. 387(17), p. 1547–1556. doi: 10.1056/NEJMoa2208375. Full text in Research Archive Show summary

  Background: Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear. Methods: We performed a pragmatic, randomized trial involving presumptively healthy men and women 55 to 64 years of age drawn from population registries in Poland, Norway, Sweden, and the Netherlands between 2009 and 2014. The participants were randomly assigned in a 1:2 ratio to either receive an invitation to undergo a single screening colonoscopy (the invited group) or to receive no invitation or screening (the usual-care group). The primary end points were the risks of colorectal cancer and related death, and the secondary end point was death from any cause. Results: Follow-up data were available for 84,585 participants in Poland, Norway, and Sweden - 28,220 in the invited group, 11,843 of whom (42.0%) underwent screening, and 56,365 in the usual-care group. A total of 15 participants had major bleeding after polyp removal. No perforations or screening-related deaths occurred within 30 days after colonoscopy. During a median follow-up of 10 years, 259 cases of colorectal cancer were diagnosed in the invited group as compared with 622 cases in the usual-care group. In intention-to-screen analyses, the risk of colorectal cancer at 10 years was 0.98% in the invited group and 1.20% in the usual-care group, a risk reduction of 18% (risk ratio, 0.82; 95% confidence interval [CI], 0.70 to 0.93). The risk of death from colorectal cancer was 0.28% in the invited group and 0.31% in the usual-care group (risk ratio, 0.90; 95% CI, 0.64 to 1.16). The number needed to invite to undergo screening to prevent one case of colorectal cancer was 455 (95% CI, 270 to 1429). The risk of death from any cause was 11.03% in the invited group and 11.04% in the usual-care group (risk ratio, 0.99; 95% CI, 0.96 to 1.04). Conclusions: In this randomized trial, the risk of colorectal cancer at 10 years was lower among participants who were invited to undergo screening colonoscopy than among those who were assigned to no screening. (Funded by the Research Council of Norway and others; NordICC ClinicalTrials.gov number, NCT00883792.).

• Juul, Frederik Emil; Cross, Amanda J.; Schoen, Robert E.; Senore, Carlo; Pinsky, Paul & Miller, Eric [Show all 17 contributors for this article] (2022). 15-Year Benefits of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality : A Pooled Analysis of Randomized Trials. Annals of Internal Medicine. ISSN 0003-4819. 175(11), p. 1525–1533. doi: 10.7326/M22-0835. Show summary

  Background: The effectiveness of screening for colorectal cancer (CRC) by sex and age in randomized trials is uncertain. Objective: To evaluate the 15-year effect of sigmoidoscopy screening on CRC incidence and mortality. Design: Pooled analysis of 4 large-scale randomized trials of sigmoidoscopy screening. Setting: Norway, the United States, the United Kingdom, and Italy. Participants: Women and men aged 55 to 64 years at enrollment. Intervention: Sigmoidoscopy screening. Measurements: Primary end points were cumulative incidence rate ratio (IRR) and mortality rate ratio (MRR) and rate differences after 15 years of follow-up comparing screening versus usual care in intention-to-treat analyses. Stratified analyses were done by sex, cancer site, and age at screening. Results: Analyses comprised 274 952 persons (50.7% women), 137 493 in the screening and 137 459 in the usual care group. Screening attendance was 58% to 84%. After 15 years, the rate difference for CRC incidence was 0.51 cases (95% CI, 0.40 to 0.63 cases) per 100 persons and the IRR was 0.79 (CI, 0.75 to 0.83). The rate difference for CRC mortality was 0.13 deaths (CI, 0.07 to 0.19 deaths) per 100 persons, and the MRR was 0.80 (CI, 0.72 to 0.88). Women had less benefit from screening than men for CRC incidence (IRR for women, 0.84 [CI, 0.77 to 0.91]; IRR for men, 0.75 [CI, 0.70 to 0.81]; P = 0.032 for difference) and mortality (MRR for women, 0.91 [CI, 0.77 to 1.17]; MRR for men, 0.73 [CI, 0.64 to 0.83]; P = 0.025 for difference). There was no statistically significant difference in screening effect between persons aged 55 to 59 years and those aged 60 to 64 years. Limitation: Data from the U.K. trial were less granular because of privacy regulations. Conclusion: This pooled analysis of all large randomized trials of sigmoidoscopy screening demonstrates a significant and sustained effect of sigmoidoscopy on CRC incidence and mortality for 15 years.

• Akwiwu, Eddymurphy U.; Klausch, Thomas; Jodal, Henriette C.; Carvalho, Beatriz; Løberg, Magnus & Kalager, Mette [Show all 8 contributors for this article] (2022). A progressive three-state model to estimate time to cancer: a likelihood-based approach. BMC Medical Research Methodology. ISSN 1471-2288. 22(1). doi: 10.1186/s12874-022-01645-2.
• Ainechi, Diba; Misawa, Masashi; Barua, Ishita; Larsen, Solveig; Paulsen, Vemund & Garborg, Kjetil Kjeldstad [Show all 21 contributors for this article] (2022). Impact of artificial intelligence on colorectal polyp detection for early-career endoscopists: an international comparative study. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. doi: 10.1080/00365521.2022.2070436. Full text in Research Archive
• Jodal, Henriette C.; Juul, Frederik Emil; Barua, Ishita; Bretthauer, Michael; Kalager, Mette & Løberg, Magnus [Show all 7 contributors for this article] (2022). Emergency hospital admissions, prognosis, and population mortality in Norway during the first wave of the Covid-19 epidemic. Scandinavian Journal of Public Health. ISSN 1403-4948. 50(6), p. 795–802. doi: 10.1177/14034948221082959. Full text in Research Archive
• Barua, Ishita; Wieszczy, Paulina; Kudo, Shin-ei; Masashi, Misawa; Holme, Øyvind & Gulati, Shraddha [Show all 34 contributors for this article] (2022). Real-Time Artificial Intelligence–Based Optical Diagnosis of Neoplastic Polyps during Colonoscopy. NEJM Evidence. ISSN 2766-5526. 1(6). doi: 10.1056/EVIDoa2200003.
• Yu, Jingru; Refsum, Erle; Perrin, Vera; Helsingen, Lise Mørkved; Wieszczy, Paulina & Løberg, Magnus [Show all 11 contributors for this article] (2022). Inflammatory bowel disease and risk of adenocarcinoma and neuroendocrine tumors in the small bowel. Annals of Oncology. ISSN 0923-7534. p. 1–8. doi: 10.1016/j.annonc.2022.02.226.
• Yu, Jingru; Refsum, Erle; Helsingen, Lise Mørkved; Folseraas, Trine; Ploner, Alexander & Wieszczy, Paulina [Show all 15 contributors for this article] (2022). Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study. United European Gastroenterology Journal (UEG Journal). ISSN 2050-6406. 10(2), p. 212–224. doi: 10.1002/ueg2.12204. Full text in Research Archive
• Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Skaug, Thomas Renhult & Nordseth, Trond [Show all 8 contributors for this article] (2022). Characteristics of circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study. Open heart. ISSN 2053-3624. 9(1). doi: 10.1136/openhrt-2021-001890. Full text in Research Archive
• Pedersen, Ina Borgenheim; Rawa-Goleblewska, Anna; Calderwood, Audrey H.; Brix, Lone D.; Grode, Louise B. & Botteri, Edoardo [Show all 17 contributors for this article] (2022). Complete Polyp Resection with Cold versus Hot snare Polypectomy for Polyps sized 4-9 mm: A randomized controlled trial. Endoscopy. ISSN 0013-726X. 54(10), p. 961–969. doi: 10.1055/a-1734-7952. Show summary

  Background: Endoscopic screening with polypectomy reduces the incidence of colorectal cancer (CRC). Incomplete polyp removal may attenuate the effect of screening. This randomized trial compared cold snare polypectomy (CSP) with hot snare polypectomy (HSP) in terms of complete polyp resection. Methods: We included patients ≥ 40 years of age at eight hospitals in four countries who had at least one non-pedunculated polyp of 4-9 mm detected at colonoscopy. Patients were randomized 1:1 to CSP or HSP. Biopsies from the resection margins were obtained systematically after polypectomy in both groups. We hypothesized that CSP would be non-inferior to HSP, with a non-inferiority margin of 5 %. Logistic regression models were fitted to identify the factors explaining incomplete resection. Results: 425 patients, with 601 polyps, randomized to either CSP or HSP were included in the analysis. Of 318 polyps removed by CSP and 283 polyps removed by HSP, 34 (10.7 %) and 21 (7.4 %) were incompletely resected, respectively, with an adjusted risk difference of 3.2 % (95 %CI -1.4 % to 7.8 %). There was no difference between the groups in terms of post-polypectomy bleeding, perforation, or abdominal pain. Independent risk factors for incomplete removal were serrated histology (odds ratio [OR] 3.96; 95 %CI 1.63 to 9.66) and hyperplastic histology (OR 2.52; 95 %CI 1.30 to 4.86) in adjusted analyses. Conclusion: In this randomized trial, non-inferiority for CSP could not be demonstrated. Polyps with serrated histology are more prone to incomplete resection compared with adenomas. CSP can be used safely for small polyps in routine colonoscopy practice.

• Wieszczy, Paulina; Waldmann, Elisabeth; Løberg, Magnus; Regula, Jaroslaw; Rupinski, Maciej & Bugajski, Marek [Show all 11 contributors for this article] (2021). Colonoscopist Performance and Colorectal Cancer Risk After Adenoma Removal to Stratify Surveillance: Two Nationwide Observational Studies. Gastroenterology. ISSN 0016-5085. 160(4), p. 1067–1074.e6. doi: 10.1053/j.gastro.2020.10.009.
• Langeland, Halvor Johannes Breivik; Damås, Jan Kristian; Mollnes, Tom Eirik; Ludviksen, Judith K; Ueland, Thor & Michelsen, Annika Elisabet [Show all 11 contributors for this article] (2021). The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study. Resuscitation. ISSN 0300-9572. 170, p. 115–125. doi: 10.1016/j.resuscitation.2021.11.026. Full text in Research Archive Show summary

  Background: Whole body ischemia and reperfusion injury after cardiac arrest leads to the massive inflammation clinically manifested in the post-cardiac arrest syndrome. Previous studies on the inflammatory effect on circulatory failure after cardiac arrest have either investigated a selected patient group or a limited part of the inflammatory mechanisms. We examined the association between cardiac arrest characteristics and inflammatory biomarkers, and between inflammatory biomarkers and circulatory failure after cardiac arrest, in an unselected patient cohort. Methods: This was a prospective study of 50 consecutive patients with out-of-hospital cardiac arrest. Circulation was invasively monitored from admission until day five, whereas inflammatory biomarkers, i.e. complement activation, cytokines and endothelial injury, were measured daily. We identified predictors for an increased inflammatory response, and associations between the inflammatory response and circulatory failure. Results: We found a marked and broad inflammatory response in patients after cardiac arrest, which was associated with clinical outcome. Long time to return of spontaneous circulation and high lactate level at admission were associated with increased complement activation (TCC and C3bc), pro-inflammatory cytokines (IL-6, IL-8) and endothelial injury (syndecan-1) at admission. These biomarkers were in turn significantly associated with lower mean arterial blood pressure, lower cardiac output and lower systemic vascular resistance, and increased need of circulatory support in the initial phase. High levels of TCC and IL-6 at admission were significantly associated with increased 30-days mortality. Conclusion: Inflammatory biomarkers, including complement activation, cytokines and endothelial injury, were associated with increased circulatory failure in the initial period after cardiac arrest.

• Helsingen, Lise Mørkved; Løberg, Magnus; Refsum, Erle; Gjøstein, Dagrun Kyte; Wieszczy, Paulina & Olsvik, Ørjan [Show all 16 contributors for this article] (2021). Covid-19 transmission in fitness centers in Norway - a randomized trial. BMC Public Health. ISSN 1471-2458. 21, p. 1–9. doi: 10.1186/s12889-021-12073-0. Full text in Research Archive
• Jodal, Henriette C.; Klotz, Dagmar; Herfindal, Magnhild; Barua, Ishita; Tag, Petter & Helsingen, Lise Mørkved [Show all 12 contributors for this article] (2021). Long-term colorectal cancer incidence and mortality after adenoma removal in women and men. Alimentary Pharmacology and Therapeutics. ISSN 0269-2813. p. 1–10. doi: 10.1111/apt.16686.
• Tønnesen, Christer Julseth; Hjelmesæth, Jøran; Hofsø, Dag; Tonstad, Serena; Hertel, Jens Kristoffer & Heggen, Eli [Show all 14 contributors for this article] (2021). A novel intragastric balloon for treatment of obesity and type 2 diabetes. A two-center pilot trial. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 57(2), p. 232–238. doi: 10.1080/00365521.2021.1994641. Full text in Research Archive
• Juul, Frederik E.; Jodal, Henriette C.; Barua, Ishita; Refsum, Erle; Olsvik, Ørjan & Helsingen, Lise Mørkved [Show all 10 contributors for this article] (2021). Mortality in Norway and Sweden during the COVID-19 pandemic. Scandinavian Journal of Public Health. ISSN 1403-4948. p. 1–8. doi: 10.1177/14034948211047137. Full text in Research Archive
• Langeland, Halvor; Bergum, Daniel; Nordseth, Trond; Løberg, Magnus; Skaug, Thomas Renhult & Bjørnstad, Knut [Show all 9 contributors for this article] (2021). Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study. BMC Anesthesiology. ISSN 1471-2253. 21, p. 1–11. doi: 10.1186/s12871-021-01434-2. Full text in Research Archive Show summary

  Background: Circulatory failure frequently occurs after out-of-hospital cardiac arrest (OHCA) and is part of postcardiac arrest syndrome (PCAS). The aim of this study was to investigate circulatory disturbances in PCAS by assessing the circulatory trajectory during treatment in the intensive care unit (ICU). Methods: This was a prospective single-center observational cohort study of patients after OHCA. Circulation was continuously and invasively monitored from the time of admission through the following fve days. Every hour, patients were classifed into one of three predefned circulatory states, yielding a longitudinal sequence of states for each patient. We used sequence analysis to describe the overall circulatory development and to identify clusters of patients with similar circulatory trajectories. We used ordered logistic regression to identify predictors for cluster membership. Results: Among 71 patients admitted to the ICU after OHCA during the study period, 50 were included in the study. The overall circulatory development after OHCA was two-phased. Low cardiac output (CO) and high systemic vascular resistance (SVR) characterized the initial phase, whereas high CO and low SVR characterized the later phase. Most patients were stabilized with respect to circulatory state within 72 h after cardiac arrest. We identifed four clusters of circulatory trajectories. Initial shockable cardiac rhythm was associated with a favorable circulatory trajectory, whereas low base excess at admission was associated with an unfavorable circulatory trajectory. Conclusion: Circulatory failure after OHCA exhibits time-dependent characteristics. We identifed four distinct circu‑latory trajectories and their characteristics. These fndings may guide clinical support for circulatory failure after OHCA. Trial registration: ClinicalTrials.gov: NCT02648061

• Wieszczy, Paulina; Kaminski, Michal F; Løberg, Magnus; Bugajski, Marek; Bretthauer, Michael & Kalager, Mette (2021). Estimation of overdiagnosis in colorectal cancer screening with sigmoidoscopy and faecal occult blood testing: Comparison of simulation models. BMJ Open. ISSN 2044-6055. 11(4), p. 1–10. doi: 10.1136/bmjopen-2020-042158.
• Tønnesen, Christer Julseth; Young, Juliet; Glomsaker, Tom Birger; Mala, Tom; Løberg, Magnus & Bretthauer, Michael [Show all 8 contributors for this article] (2020). Laparoscopy-assisted versus balloon enteroscopy-assisted ERCP after Roux-en-Y gastric bypass. Endoscopy. ISSN 0013-726X. 52(8), p. 654–661. doi: 10.1055/a-1139-9313.
• Helsingen, Lise M.; Refsum, Erle; Gjøstein, Dagrun Kyte; Løberg, Magnus; Bretthauer, Michael & Kalager, Mette [Show all 7 contributors for this article] (2020). The COVID-19 pandemic in Norway and Sweden – threats, trust, and impact on daily life: a comparative survey. BMC Public Health. ISSN 1471-2458. 20:1597, p. 1–10. doi: 10.1186/s12889-020-09615-3. Full text in Research Archive
• Pedersen, Ina Borgenheim; Bretthauer, Michael; Kalager, Mette; Løberg, Magnus; Hoff, Geir & Matapour, Senaria [Show all 13 contributors for this article] (2020). Incomplete endoscopic resection of colorectal polyps: a prospective quality assurance study. Endoscopy. ISSN 0013-726X. p. 1–9. doi: 10.1055/a-1243-0379.
• Barua, Ishita; Guerrero Vinsard, Daniela; Jodal, Henriette C.; Løberg, Magnus; Kalager, Mette & Holme, Øyvind [Show all 9 contributors for this article] (2020). Artificial intelligence for polyp detection during colonoscopy: A systematic review and meta-analysis. Endoscopy. ISSN 0013-726X. doi: 10.1055/a-1201-7165.
• Wieszczy, Paulina; Kamiński, Michał Filip; Franczyk, Robert; Løberg, Magnus; Kobiela, Jarek & Rupinska, Maria [Show all 15 contributors for this article] (2019). Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies. Gastroenterology. ISSN 0016-5085. 158(4), p. 875–883. doi: 10.1053/j.gastro.2019.09.011.
• Bleijenberg, Arne; Klotz, Dagmar; Løberg, Magnus; Dekker, Evelien; Adami, Hans Olov & Kuipers, Ernst J. [Show all 15 contributors for this article] (2019). Implications of different guidelines for surveillance after serrated polyp resection in United States of America and Europe. Endoscopy. ISSN 0013-726X. 51(8), p. 750–758. doi: 10.1055/a-0916-8598.
• Hoff, Geir; Ursin, Giske; Løberg, Magnus; de Lange, Thomas; Skovlund, Eva & Holme, Øyvind (2019). Continuous development of colorectal cancer screening programs. Acta Oncologica. ISSN 0284-186X. 3(1), p. 822–823. doi: 10.1080/0284186X.2019.1588475. Full text in Research Archive
• Jodal, Henriette Cecilie; Løberg, Magnus; Holme, Øyvind; Adami, Hans Olov; Bretthauer, Michael & Emilsson, Louise [Show all 9 contributors for this article] (2018). Mortality from post-screening (interval) colorectal cancers is comparable to that from cancer in unscreened patients-a randomized sigmoidoscopy trial. Gastroenterology. ISSN 0016-5085. 155(6), p. 1787–1794. doi: 10.1053/j.gastro.2018.08.035.
• Bretthauer, Michael; Goderstad, Jeanne Mette; Løberg, Magnus; Emilsson, Louise; Ye, Weimin & Adami, Hans Olov [Show all 7 contributors for this article] (2018). Uterine morcellation and survival in uterine sarcomas. European Journal of Cancer. ISSN 0959-8049. 101, p. 62–68. doi: 10.1016/j.ejca.2018.06.007.
• Juul, Frederik Emil; Garborg, Kjetil Kjeldstad; Bretthauer, Michael; Skudal, Hilde Kristin; Oines, Mari N. & Wiig, Håvard [Show all 16 contributors for this article] (2018). Fecal microbiota transplantation for primary Clostridium difficile infection. New England Journal of Medicine. ISSN 0028-4793. 378(26), p. 2535–2537. doi: 10.1056/NEJMc1803103. Full text in Research Archive
• Pedersen, Ina Borgenheim; Løberg, Magnus; Hoff, Geir; Kalager, Mette; Bretthauer, Michael & Holme, Øyvind (2018). Polypectomy techniques among gastroenterologists in Norway – a nationwide survey. Endoscopy International Open. ISSN 2196-9736. 6(7). doi: 10.1055/a-0607-0727. Full text in Research Archive
• Pinsky, Paul F.; Løberg, Magnus; Senore, Carlo; Wooldrage, Kate; Atkin, Wendy S. & Bretthauer, Michael [Show all 12 contributors for this article] (2018). Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening. Gastroenterology. ISSN 0016-5085. 155(4), p. 1059–1068. doi: 10.1053/j.gastro.2018.06.040.
• Holme, Øyvind; Løberg, Magnus; Kalager, Mette; Bretthauer, Michael; Hernán, Miguel A. & Aas, Eline [Show all 14 contributors for this article] (2018). Long-term effectiveness of sigmoidoscopy screening on colorectal cancer incidence and mortality in women and men: A randomized trial. Annals of Internal Medicine. ISSN 0003-4819. 168(11), p. 775–782. doi: 10.7326/M17-1441. Full text in Research Archive
• Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian & Mollnes, Tom Eirik [Show all 8 contributors for this article] (2018). Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study. JMIR Research Protocols. ISSN 1929-0748. 7(1). doi: 10.2196/resprot.8558. Full text in Research Archive
• Holme, Øyvind; Pedersen, Ina Borgenheim; Medhus, Asle Wilhelm; Aabakken, Lars; Glomsaker, Tom Birger & Kvamme, Jan-Magnus [Show all 14 contributors for this article] (2018). Endoscopy assistants influence the quality of colonoscopy. Endoscopy. ISSN 0013-726X. 50(9), p. 871–877. doi: 10.1055/s-0044-101706. Full text in Research Archive
• Emilsson, Louise; Løberg, Magnus; Bretthauer, Michael; Holme, Øyvind; Fall, Katja & Jodal, Henriette Cecilie [Show all 8 contributors for this article] (2017). Colorectal cancer death after adenoma removal in Scandinavia. Scandinavian Journal of Gastroenterology. ISSN 0036-5521. 52(12), p. 1377–1384. doi: 10.1080/00365521.2017.1377763.
• Holme, Øyvind; Schoen, Robert E.; Senore, Carlo; Segnan, Nereo; Hoff, Geir & Løberg, Magnus [Show all 9 contributors for this article] (2017). Effectiveness of flexible sigmoidoscopy screening in men and women and different age groups: Pooled analysis of randomised trials. The BMJ. ISSN 1756-1833. 356. doi: 10.1136/bmj.i6673. Full text in Research Archive
• Adami, Hans Olov; Csermely, Peter; Veres, DV; Emilsson, Louise; Løberg, Magnus & Bretthauer, Michael [Show all 7 contributors for this article] (2017). Are rapidly growing cancers more lethal? European Journal of Cancer. ISSN 0959-8049. 72, p. 210–214. doi: 10.1016/j.ejca.2016.11.011.
• Garborg, Kjetil Kjeldstad; Wiig, Håvard; Hasund, Audun; Matre, Jon; Holme, Øyvind & Noraberg, Geir [Show all 10 contributors for this article] (2017). Gradual stiffness versus magnetic imaging-guided variable stiffness colonoscopes: A randomized noninferiority trial. United European Gastroenterology Journal (UEG Journal). ISSN 2050-6406. 5(1), p. 128–133. doi: 10.1177/2050640616639162.
• Emilsson, Louise; Holme, Øyvind; Bretthauer, Michael; Cook, Nancy R.; Buring, Julie E. & Løberg, Magnus [Show all 10 contributors for this article] (2017). Systematic review with meta-analysis: the comparative effectiveness of aspirin vs. screening for colorectal cancer prevention. Alimentary Pharmacology and Therapeutics. ISSN 0269-2813. 45(2), p. 193–204. doi: 10.1111/apt.13857.
• Holme, Øyvind & Løberg, Magnus (2016). Methodological considerations for surveillance in GI practice. Baillière's Best Practice & Research : Clinical Gastroenterology. ISSN 1521-6918. 30(6), p. 867–878. doi: 10.1016/j.bpg.2016.10.011.
• Gjøstein, Dagrun Kyte; Huitfeldt, Anders; Løberg, Magnus; Adami, Hans Olov; Garborg, Kjetil Kjeldstad & Kalager, Mette [Show all 7 contributors for this article] (2016). Incentiver og deltagelse i en medisinsk spørreundersøkelse. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(12-13), p. 1082–1087. doi: 10.4045/tidsskr.15.1096.
• Berstad, Paula Marianna; Botteri, Edoardo; Larsen, Inger Kristin; Løberg, Magnus; Kalager, Mette & Holme, Øyvind [Show all 8 contributors for this article] (2016). Lifestyle changes at middle age and mortality: A population-based prospective cohort study. Journal of Epidemiology and Community Health. ISSN 0143-005X. 71(1), p. 59–66. doi: 10.1136/jech-2015-206760.
• Bretthauer, Michael; Kaminski, Michal Filip; Løberg, Magnus; Zauber, Ann G.; Regula, Jaroslaw & Kuipers, Ernst J. [Show all 20 contributors for this article] (2016). Population-Based colonoscopy screening for colorectal cancer : A randomized clinical trial. JAMA Internal Medicine. ISSN 2168-6106. 176(7), p. 894–902. doi: 10.1001/jamainternmed.2016.0960.
• Holme, Øyvind; de Lange, Thomas; Stallemo, Asbjørn; Wiig, Håvard; Hasund, Audun & Dvergsnes, Katrine [Show all 12 contributors for this article] (2016). Routine vs. on-demand analgesia in colonoscopy: a randomized clinical trial. Endoscopy. ISSN 0013-726X. 48(09), p. 823–828. doi: 10.1055/s-0042-108433.
• Jover, Rodrigo; Bretthauer, Michael; Dekker, Evelien; Holme, Øyvind; Kaminski, Michal Filip & Løberg, Magnus [Show all 22 contributors for this article] (2016). Rationale and design of the European Polyp Surveillance (EPoS) trials. Endoscopy. ISSN 0013-726X. 48(6), p. 571–578. doi: 10.1055/s-0042-104116.
• Moritz, Volker; Bretthauer, Michael; Holme, Øyvind; Fagerland, Morten; Løberg, Magnus & Glomsaker, Tom Birger [Show all 10 contributors for this article] (2016). Time trends in quality indicators of colonoscopy. United European Gastroenterology Journal (UEG Journal). ISSN 2050-6406. 4(1), p. 110–120. doi: 10.1177/2050640615570147.
• Swanson, Sonja; Holme, Øyvind; Løberg, Magnus; Kalager, Mette; Bretthauer, Michael & Hoff, Geir [Show all 8 contributors for this article] (2015). Bounding the per-protocol effect in randomized trials: an application to colorectal cancer screening. Trials. ISSN 1745-6215. 16(541). doi: 10.1186/s13063-015-1056-8.
• Holme, Øyvind; Bretthauer, Michael; Eide, Tor Jacob; Løberg, Else Marit; Grzyb, Krzysztof & Løberg, Magnus [Show all 10 contributors for this article] (2015). Long-term risk of colorectal cancer in individuals with serrated polyps. Gut. ISSN 0017-5749. 64(6), p. 929–936. doi: 10.1136/gutjnl-2014-307793.
• Løberg, Magnus; Lousdal, Mette Lise; Bretthauer, Michael & Kalager, Mette (2015). Benefits and harms of mammography screening. Breast Cancer Research. ISSN 1465-5411. 17(1). doi: 10.1186/s13058-015-0525-z.
• Berstad, Paula Marianna; Løberg, Magnus; Larsen, Inger Kristin; Kalager, Mette; Holme, Øyvind & Botteri, Edoardo [Show all 8 contributors for this article] (2015). Long-term lifestyle changes after colorectal cancer screening: randomised controlled trial. Gut. ISSN 0017-5749. 64(8), p. 1268–1276. doi: 10.1136/gutjnl-2014-307376.
• Bretthauer, Michael; Løberg, Magnus & Kalager, Mette (2014). Long-term colorectal-cancer mortality after adenoma removal. New England Journal of Medicine. ISSN 0028-4793. doi: 10.1056/NEJMc1411954.
• Holme, Øyvind; Bretthauer, Michael; Eide, Tor Jacob; Løberg, Else Marit; Grzyb, Krzysztof & Løberg, Magnus [Show all 10 contributors for this article] (2014). Long-term risk of colorectal cancer in individuals with serrated polyps. . Gut. ISSN 0017-5749. doi: 10.1136/gutjnl-2014-307793.
• Løberg, Magnus; Kalager, Mette; Holme, Øyvind; Hoff, Geir; Adami, Hans Olov & Bretthauer, Michael (2014). Long-Term Colorectal-Cancer Mortality after Adenoma Removal. New England Journal of Medicine. ISSN 0028-4793. 371(9), p. 799–807. doi: 10.1056/NEJMoa1315870.
• Kalager, Mette; Løberg, Magnus; Bretthauer, Michael & Adami, Hans Olov (2014). Comparative analysis of breast cancer mortality following mammography screening in Denmark and Norway. Annals of Oncology. ISSN 0923-7534. 25(6), p. 1137–1143. doi: 10.1093/annonc/mdu122.

View all works in Cristin

• Jodal, Henriette C.; Bretthauer, Michael & Løberg, Magnus (2023). Tarmkreftscreening også for yngre? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(18), p. 1–5. doi: 10.4045/tidsskr.23.0553.
• Cross, Amanda J; Senore, Carlo; Schoen, Robert E. & Løberg, Magnus (2023). Author response to Olsen. Annals of Internal Medicine. ISSN 0003-4819. doi: 10.7326/M22-0835.
• Jodal, Henriette C.; Wieszczy, Paulina & Løberg, Magnus (2023). Reply. Gastroenterology. ISSN 0016-5085. 165(6), p. 1583–1584. doi: 10.1053/j.gastro.2023.09.022.
• Feiring, Eli; Løberg, Magnus; Bjaalie, Jan G.; Dyb, Grete Anita & Harbo, Hanne-Cathrin Flinstad (2023). Kjønn og helse, utdanning og forskning. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 143(11). doi: 10.4045/tidsskr.23.0408.
• Juul, Frederik Emil; Cross, Amanda J.; Pinsky, Paul; Senore, Carlo & Løberg, Magnus (2023). 15-Year Benefits of Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality. Annals of Internal Medicine. ISSN 0003-4819. 176(6). doi: 10.7326/L23-0025.
• Hanley, James A.; Deck, Wilber; Winawer, Sidney J.; Hoffmeister, Michael; Cardoso, Rafael & Brenner, Hermann [Show all 14 contributors for this article] (2023). Colonoscopy Screening and Colorectal Cancer Incidence and Mortality. New England Journal of Medicine. ISSN 0028-4793. 388(4), p. 376–379. doi: 10.1056/NEJMc2215192.
• Helsingen, Lise Mørkved; Løberg, Magnus; Bretthauer, Michael & Kalager, Mette (2022). Reply to: Letter to the Editor regarding "Covid-19 transmission in fitness centers in Norway-a randomized trial". BMC Public Health. ISSN 1471-2458. 22(1). doi: 10.1186/s12889-022-14799-x.
• Jodal, Henriette C.; Bretthauer, Michael; Kalager, Mette & Løberg, Magnus (2022). Letter: long-term colorectal cancer incidence and mortality after adenoma removal associated with heritable factors, colonoscopic surveillance and aspirin—authors' reply. Alimentary Pharmacology and Therapeutics. ISSN 0269-2813. 55(10), p. 1363–1364. doi: 10.1111/apt.16929.
• Jodal, Henriette C. & Løberg, Magnus (2022). Letter: towards gender-stratified colorectal cancer screening and surveillance? Authors’ reply. Alimentary Pharmacology and Therapeutics. ISSN 0269-2813. 55(4), p. 506–507. doi: 10.1111/apt.16764.
• Øverenget, Einar; Kalager, Mette; Grødeland, Gunnveig; Olsvik, Ørjan; Nylund, Anna & Løberg, Magnus [Show all 8 contributors for this article] (2022). Når smittevern blir uforståelig. Dagensnæringsliv.
• Bretthauer, Michael; Løberg, Magnus; Holme, Øyvind; Adami, Hans-Olov & Kalager, Mette (2021). Deep learning and cancer biomarkers: recognising lead-time bias. The Lancet. ISSN 0140-6736. 397(10270). doi: 10.1016/S0140-6736(20)32402-8.
• Rutter, Matthew D.; Bretthauer, Michael; Hassan, Cesare; Jover, Rodrigo; Adami, Hans-Olov & Corley, Douglas A. [Show all 20 contributors for this article] (2020). Principles for Evaluation of Surveillance After Removal of Colorectal Polyps: Recommendations From the World Endoscopy Organization. Gastroenterology. ISSN 0016-5085. 158(6), p. 1529–1533.e4. doi: 10.1053/j.gastro.2019.12.052.
• Løberg, Magnus & Bretthauer, Michael (2020). Presentasjon av tall: Ikke la deg lure. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 140(8), p. 1–2. doi: 10.4045/tidsskr.20.0378.
• Holme, Øyvind; Bretthauer, Michael; Løberg, Magnus; Kalager, Mette & Adami, Hans-Olov (2019). Reply to the letter to the editor 'Cancer survivors: Surveillance or not surveillance?' by Santeufemia and Miolo. Annals of Oncology. ISSN 0923-7534. 30(9). doi: 10.1093/annonc/mdz190.
• Holme, Øyvind; Bretthauer, Michael; Løberg, Magnus; Kalager, Mette & Adami, Hans Olov (2019). Revisiting surveillance schemes for cancer survivors. Annals of Oncology. ISSN 0923-7534. 30(6), p. 881–883. doi: 10.1093/annonc/mdz107.
• Sarjomaa, Marjut Anneli; Majak, Bernard; Ludolph, Thomas & Løberg, Magnus (2019). Forstørrede lymfeknuter og utslett hos en mann fra et middelhavsland. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 139(6), p. 1–7. doi: 10.4045/tidsskr.18.0514.
• Refsum, Erle; Helsingen, Lise M.; Jodal, Henriette Cecilie; Løberg, Magnus; Høstmælingen, Njål & Kalager, Mette (2019). Personvern – en hinderløype. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 139(4), p. 1–3. doi: 10.4045/tidsskr.19.0077.
• Juul, Frederik Emil; Skudal, Hilde Kristin; Øines, Mari Nanna; Wiig, Håvard; Rose, Øystein & Seip, Birgitte Karen Berggreen [Show all 14 contributors for this article] (2018). Fecal microbiota transplant in primary Clostridium difficile infection - a proof-of-concept trial.
• Halvorsen, Jon Anders; Løberg, Magnus; Gjersvik, Petter; Roscher, Ingrid; Veierød, Marit Bragelien & Robsahm, Trude Eid [Show all 9 contributors for this article] (2018). Why a randomized melanoma screening trial is not a good idea. British Journal of Dermatology. ISSN 0007-0963. 179, p. 532–533. doi: 10.1111/bjd.16784.
• Løberg, Magnus; Kalager, Mette & Hoff, Geir (2018). Tailoring the message with selective reporting. European Journal of Epidemiology (EJE). ISSN 0393-2990. doi: 10.1007/s10654-018-0416-6.
• Juul, Frederik Emil; Garborg, Kjetil Kjeldstad; Bretthauer, Michael; Kalager, Mette; Midtvedt, Tore & Furholm, Siv [Show all 17 contributors for this article] (2018). Fecal microbiota transplantation versus antibiotics for primary Clostridium difficile infection - a multicenter, randomized proof-of-concept trial.
• Jodal, Henriette Cecilie; Løberg, Magnus; Emilsson, Louise; Adami, Hans Olov; Bretthauer, Michael & Kalager, Mette (2018). Surveillance after Adenoma Removal (SAR): en case-kohort studie.
• Løberg, Magnus; Holme, Øyvind; Bretthauer, Michael & Kalager, Mette (2017). Colorectal adenomas, surveillance, and cancer. The Lancet Oncology. ISSN 1470-2045. 18:e427(8), p. 1–1. doi: 10.1016/S1470-2045(17)30473-4.
• Bretthauer, Michael; Vandvik, Per Olav; Skjeldestad, Finn Egil; Frich, Jan C; de Lange, Thomas & Løberg, Magnus (2017). Ny spesialistutdanning for leger – fra sveitserost til kraftkar? Tidsskrift for Den norske legeforening. ISSN 0029-2001. 137(17), p. 1270–1271. doi: 10.4045/tidsskr.17.0637.
• Holme, Øyvind; Løberg, Magnus; Bretthauer, Michael & Kalager, Mette (2017). Authors' reply to Doherty and Hawkins. The BMJ. ISSN 1756-1833. 356. doi: 10.1136/bmj.j1267.
• Løberg, Magnus; Holme, Øyvind & Kalager, Mette (2017). Aspirin, colorectal cancer, and cause of death: A complex landscape. Journal of Clinical Oncology. ISSN 0732-183X. 35(5), p. 568–569. doi: 10.1200/JCO.2016.70.3751.
• Jodal, Henriette Cecilie; Løberg, Magnus; Adami, Hans Olov; Bretthauer, Michael; Hoff, Geir & Kalager, Mette (2016). Interval Colorectal Cancers after Screening - More Aggressive than Clinical Cancers?
• Løberg, Magnus; Emilsson, Louise; Jodal, Henriette Cecilie; Bretthauer, Michael; Holme, Øyvind & Adami, Hans Olov [Show all 7 contributors for this article] (2016). Surveillance After Adenoma Removal: Does It Make a Difference?
• Zahl, P-H; Holme, Øyvind & Løberg, Magnus (2016). Norsk mammografiscreening - mange selvmotsigelser i evalueringen :. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(19), p. 1616–1618. doi: 10.4045/tidsskr.16.0165.
• Løberg, Magnus; Kalager, Mette & Bretthauer, Michael (2016). "Randomize, Then Consent" or "Consent, Then Randomize"?: Revitalizing the Issue of Preconsent Randomization. Epidemiology. ISSN 1044-3983. doi: 10.1097/EDE.0000000000000469.
• Bretthauer, Michael; Kaminski, Michal Filip; Hassan, Cecare; Kalager, Mette; Holme, Øyvind & Hoff, Geir [Show all 10 contributors for this article] (2016). America, We Are Confused: The Updated U.S. Preventive Services Task Force Recommendation on Colorectal Cancer Screening. Annals of Internal Medicine. ISSN 0003-4819. 166(2), p. 139–140. doi: 10.7326/M16-1805.
• Holme, Øyvind; Hoff, Geir & Løberg, Magnus (2016). Colorectal cancer screening. Journal of the American Medical Association (JAMA). ISSN 0098-7484. 316(16), p. 1714–1714. doi: 10.1001/jama.2016.13846.
• Gjøstein, Dagrun Kyte; Bretthauer, Michael & Løberg, Magnus (2016). D.K. Gjøstein og medarbeidere svarer:. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 136(16), p. 1326–1327. doi: 10.4045/tidsskr.16.0690.
• Løberg, Magnus (2015). Screening for tarmkreft virker. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(18), p. 1676–1676. doi: 10.4045/tidsskr.15.0724.
• Holme, Øyvind; Løberg, Magnus & Kalager, Mette (2014). In reply. Journal of the American Medical Association (JAMA). ISSN 0098-7484. 312(22), p. 2411–2412. doi: 10.1001/jama.2014.14695.
• Bretthauer, Michael; Løberg, Magnus & Kalager, Mette (2014). The authors reply. New England Journal of Medicine. ISSN 0028-4793. 371(21), p. 2036–2037. doi: 10.1056/NEJMc1411954.

View all works in Cristin