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Targeting lifestyle to improve colorectal cancer screening - KoloPrev

Norway has just implemented a national colorectal cancer-screening program. We aim to enhance the screening program by targeting lifestyle.

Colourfull running shoes, fruits and vegetables on a table

Illustration: Colourbox

About the project 

Norway has one of the highest incidence of colorectal cancer in the world. Attending colorectal cancer screening may serve as a window of opportunity to draw the participant's attention to cancer preventive behaviours. Diet and lifestyle are known risk factors of colorectal cancer, but we do not know whether improvement in lifestyle prevents colorectal cancer in addition to screening.

In order to implement preventive strategies at screening, we need suitable assessment tools for diet and lifestyle, followed by intervention measures which are acceptable, effective and feasible in screening. Also, as colonoscopy screening is resource demanding it is worth examining if the interval between screening rounds can be extended for those with a low risk profile.


To examine the need and feasibility to promote lifestyle changes at colorectal cancer screening.

We will achieve this by

  • Examine in an observational Norwegian study the association between lifestyle changes and risk of lifestyle-related cancers in individuals screened for colorectal cancer.
  • Test in a randomized trial if a personalized, digital diet and lifestyle intervention linked to a screening program leads to change in lifestyle, and whether its efficacy depends on the intensity of the intervention. 
  • In large U.S. cohorts, examine the possibility to extend endoscopy screening interval in those with a low risk, and the effect of lifestyle changes on colorectal cancer risk. 


  • The Norwegian Cancer Society 
  • Institute of Basic Medical Sciences, University of Oslo
  • The Cancer Registry of Norway

Start – finish

2022 - 2026


Tags: Lifestyle, diet, colorectal cancer, screening
Published May 16, 2022 2:49 PM - Last modified May 16, 2022 2:51 PM