Publikasjoner

Her er et utvalg av gruppens publikasjoner

  • Pihlstrøm L, Shireby G, Geut H, Henriksen SP, Rozemuller AJM, Tunold JA, Hannon E, Francis P, Thomas AJ, Love S, Mill J, van de Berg WDJ, Toft M. Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology. Nat Commun 2022;13:4932
  • Tunold JA, Tan M, Koga S, Geut H, Rozemuller AJM, Valentino R, Sekiya H, Martin NB, Heckman MG, Bras J, Guerreiro R, Dickson DW, Toft M, van de Berg W, Ross OA, Pihlstrøm L. Lysosomal polygenic risk is associated with the severity of neuropathology in Lewy body disease. Brain 2023: doi.org/10.1093/brain/awad183.
  • Tunold JA, Tan MMX, Toft M, Ross O, van de Berg WDJ, Pihlstrøm L. Lysosomal Polygenic Burden Drives Cognitive Decline in Parkinson's Disease with Low Alzheimer Risk. Mov Disord 2023;39:596-601
  • Andersen MS, Bandres-Ciga S, Reynolds RH, Hardy J, Ryten M, Krohn L, Gan-Or Z, Holtman IR, Pihlstrøm L; International Parkinson's Disease Genomics Consortium. Heritability enrichment implicates microglia in Parkinson's disease pathogenesis. Ann Neurol 2021; 89: 942-951.
  • Pihlstrøm L, Fan CC, Frei O, Tan M, Karunamuni RA, Blauwendraat C, Bandres-Ciga S, Gan-Or Z, Grosset DG; International Parkinson's Disease Genomics Consortium (IPDGC), Dale AM, Seibert TM, Andreassen OA. Genetic stratification of age-dependent Parkinson's disease risk by polygenic hazard score. Mov Disord 2021; 37: 62-69
  • Lie IH, Maurtveten EH, Andersen MS, Dalbro SEJ, Tunold JA, Pihlstrøm L. The Menstrual Cycle and Pregnancy Commonly Impact Symptoms of Women with Early-Onset Parkinson's Disease. Mov Disord Clin Pract 2025. DOI 10.1002/mdc3.70438
  • Udayar V, Gilormini PA, Bryois J, Gehrlein A, Chen X, Sonea S, Zhu S, Deen MC, Anastasi N, Murphy AE, Skene N, Tan MMX, Tunold JA, Roudnicky F, van de Berg WDJ, Pihlstrøm L, Vocadlo DJ, Jagasia R. Enzyme Activity-Based Genome-wide Screening for Modifiers of Lysosomal Glucocerebrosidase Uncovers Candidate Risk Factors for Parkinson's Disease. ACS Cent Sci 2025, 11 (10), 1933-1945
  • Lie IH, Tan MMX, Andersen MS, Toft M, Pihlstrøm L. Epigenome-wide association study, meta-analysis, and multiscore profiling of whole blood in Parkinson's disease. Ann Clin Transl Neurol 2025;12:701-713
  • Nordengen K, Cappelletti C, Bahrami S, Frei O, Pihlstrøm L, Henriksen SP, Geut H, Rozemuller AJM, van de Berg WDJ, Andreassen OA, Toft M. Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease. Brain 2024;147:858-870
  • Murthy M, Fodder K, Miki Y, Rambarack N, De Pablo Fernandez E, Pihlstrøm L, Mill J, Warner TT, Lashley T, Bettencourt C. DNA methylation patterns in the frontal lobe white matter of multiple system atrophy, Parkinson's disease, and progressive supranuclear palsy: a cross-comparative investigation. Acta Neuropathol 2024;148:4
  • Cappelletti C, Henriksen SP, Geut H, Rozemuller AJM, van de Berg WDJ, Pihlstrøm L, Toft M. Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes. Acta Neuropathol 2023;146:227-244. doi: 10.1007/s00401-023-02597-7.
  • Grover S, Kumar Sreelatha AA, Pihlstrom L, et al. Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence From the COURAGE-PD Consortium. Neurology 2022;99:e698-e710.
  • Stolp Andersen M, Tan M, Holtman IR, Hardy J; International Parkinson's Disease Genomics Consortium, Pihlstrøm L. Dissecting the limited genetic overlap of Parkinson's and Alzheimer's disease. Ann Clin Transl Neurol 2022; 9: 1289-1295.
  • Krohn L, Heilbron K, Blauwendraat C, Reynolds RH, Yu E, Senkevich K, Rudakou U, Estiar MA, Gustavsson EK, Brolin K, Ruskey JA, Freeman K, Asayesh F, Chia R, Arnulf I, Hu MTM, Montplaisir JY, Gagnon JF, Desautels A, Dauvilliers Y, Gigli GL, Valente M, Janes F, Bernardini A, Högl B, Stefani A, Ibrahim A, Šonka K, Kemlink D, Oertel W, Janzen A, Plazzi G, Biscarini F, Antelmi E, Figorilli M, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Döring F, Cochen De Cock V, Monaca CC, Heidbreder A, Ferini-Strambi L, Dijkstra F, Viaene M, Abril B, Boeve BF; 23andMe Research Team; Scholz SW, Ryten M, Bandres-Ciga S, Noyce A, Cannon P, Pihlstrøm L, Nalls MA, Singleton AB, Rouleau GA, Postuma RB, Gan-Or Z. Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects. Nat Commun 2022;13:7496. doi: 10.1038/s41467-022-34732-5.
  • Nalls MA, Blauwendraat C, Vallerga CL, et al. Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet Neurol. 2019;18:1091-1102.
Publisert 27. mars 2026 16:12 - Sist endret 27. mars 2026 16:12
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