Benedicte Alexandra Lie

Bilde av Benedicte Alexandra Lie
English version of this page
Telefon +47-23016646
Brukernavn
Besøksadresse Kirkeveien 166 Laboratoriebygget 0450 OSLO
Postadresse Postboks 4956 Nydalen 0424 OSLO

Faglige interesser

Genetisk disposisjon for autoimmune sykdommer, som revmatoid artritt, type 1 diabetes, multippel sklerose, primær skleroserende cholangitt og myastenia gravis.

Undervisning

Modul 1

Modul 4

 

Bakgrunn

  • Cand. scient i 1995 ved Universitetet i Trondheim
  • Dr.philos i 2000 ved Universitetet i Oslo
  • Har siden 2010 vært ansatt ved avdeling for medisinsk genetikk.
  • I perioden 1996-2010 arbeidet jeg ved Immunologisk institutt som doktorgradsstipendiat, postdoktor og forsker.

Priser

  • Young Investigators Award fra Scandinavian Society for the Study of Diabetes i 2000.
  • Julia Bodmer Young Scientist Award fra European Federation of Immunogenetics i 2002.

Samarbeid

Har i tillegg en bistilling  ved Avdeling for immunologi og transfusjonsmedisin, Oslo Universitetssykehus, Rikshospitalet.

Publikasjoner

  • Størdal, Ketil; McArdle, Harry J.; Hayes, Helen; Tapia, German; Viken, Marte K; Lund-Blix, Nicolai Andre; Haugen, Margaretha; Joner, Geir; Skrivarhaug, Torild; Mårild, Karl Staffan; Njølstad, Pål Rasmus; Eggesbø, Merete Åse; Mandal, Siddhartha; Page, Christian; London, Stephanie J.; Lie, Benedicte Alexandra & Stene, Lars Christian Mørch (2018). Prenatal iron exposure and childhood type 1 diabetes. Scientific Reports.  ISSN 2045-2322.  8 . doi: 10.1038/s41598-018-27391-4
  • Henriksen, Eva Kristine Klemsdal; Viken, Marte K; Wittig, Michael; Holm, Kristian; Folseraas, Trine; Mucha, Sören; Melum, Espen; Hov, Johannes Espolin Roksund; Lazaridis, Konstantinos N.; Juran, Brian D.; Chazouillères, Olivier; Färkkilä, Martti A.; Gotthardt, Daniel Nils; Invernizzi, Pietro; Carbone, Marco; Hirschfield, Gideon Morris; Rushbrook, Simon Matthew; Goode, Elizabeth C.; Ponsioen, Cyriel Y.; Weersma, Rinse K.; Eksteen, Bertus; Yimam, Kidist K.; Gordon, Stuart C.; Goldberg, David E.; Yu, Lei; Bowlus, Christopher L.; Franke, Andre; Lie, Benedicte Alexandra & Karlsen, Tom Hemming (2017). HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry. HLA.  ISSN 2059-2302.  90(4), s 228- 233 . doi: 10.1111/tan.13076
  • Hov, Johannes Espolin Roksund; Boberg, Kirsten Muri; Taraldsrud, Eli; Vesterhus, Mette; Boyadzhieva, Maria; Solberg, Inger Camilla; Schrumpf, Erik; Vatn, Morten H; Lie, Benedicte Alexandra; Molberg, Øyvind & Karlsen, Tom Hemming (2017). Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis. Liver international (Print).  ISSN 1478-3223.  37(3), s 458- 465 . doi: 10.1111/liv.13238
  • Mårild, Karl; Tapia, German; Haugen, Margaretha; Dahl, Sandra Rinne; Cohen, Arieh S.; Lundqvist, Marika; Lie, Benedicte Alexandra; Stene, Lars Christian & Størdal, Ketil (2017). Maternal and neonatal vitamin D status, genotype and childhood celiac disease. PLoS ONE.  ISSN 1932-6203.  12(7) . doi: 10.1371/journal.pone.0179080 Fulltekst i vitenarkiv.
  • Popperud, Trine Haug; Viken, Marte K; Kerty, Emilia & Lie, Benedicte Alexandra (2017). Juvenile myasthenia gravis in Norway: HLA-DRB1*04:04 is positively associated with prepubertal onset. PLoS ONE.  ISSN 1932-6203.  12:e0186383(10), s 1- 9 . doi: 10.1371/journal.pone.0186383
  • Størdal, Ketil; Mårild, Karl; Tapia, German; Haugen, Margaretha; Cohen, Arieh S; Lie, Benedicte Alexandra & Stene, Lars Christian (2017). Fetal and maternal genetic variants influencing neonatal vitamin D status. Journal of Clinical Endocrinology and Metabolism.  ISSN 0021-972X.  102(11), s 4072- 4079 . doi: 10.1210/jc.2017-00827
  • Viken, Marte K; Flåm, Siri Tennebø; Skrivarhaug, Torild; Amundsen, Silja Svanstrøm; Sollid, Ludvig Magne; Drivvoll, Ann Kristin; Joner, Geir; Dahl-Jørgensen, Knut & Lie, Benedicte Alexandra (2017). HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease. HLA.  ISSN 2059-2302.  89(5), s 278- 284 . doi: 10.1111/tan.12986
  • Witoelar, Aree; Jansen, Iris E.; Wang, Yunpeng; Desikan, Rahul S.; Gibbs, J. Raphael; Thompson, Wesley Kurt; Hernandez, Dena G.; Djurovic, Srdjan; Schork, Andrew J.; Bettella, Francesco; Ellinghaus, David; Franke, Andre; Lie, Benedicte Alexandra; McEvoy, Linda K.; Karlsen, Tom Hemming; Lesage, Suzanne; Morris, Huw R.; Brice, Alexis; Wood, Nicholas W.; Heutink, Peter; Hardy, John; Singleton, Andrew B.; Dale, Anders; Gasser, Thomas; Andreassen, Ole Andreas & Sharma, Manu (2017). Genome-wide pleiotropy between Parkinson disease and autoimmune diseases. JAMA Neurology.  ISSN 2168-6149.  74(7), s 780- 792 . doi: 10.1001/jamaneurol.2017.0469
  • Carmona, David; Vaglio, Augusto; Mackie, Sarah L; Hernández-Rodríguez, José; Monarch, Paul A; Castaneda, Santos; Solans, Roser; Morado, Inmaculada C.; Narváez, Javier; Ramentol-Sintas, Marc; Pease, Colin T.; Dasgupta, Bhaskar; Watts, Richard; Khalidi, Nader A.; Langford, Carol A.; Ytterberg, Steven R.; Boiardi, Luigi; Beretta, Lorenzo; Govone, Marcello; Emmi, Giacomo; Bonatti, Francesco; Cimmino, Marco A.; Witte, Torsten; Neuman, Thomas; Holle, Julia; Schönau, Verena; Sailler, Laurent; Papo, Thomas; Haroche, Julien; Mahr, Alfred; Mouthon, Luc; Molberg, Øyvind; Diamantopoulos, Andreas P; Voskuyl, Alexandre; Brouwer, Elisabeth; Daikeler, Thomas; Berger, Christoph T; Molloy, Eamonn S; O'Neill, Lorraine; Blockmans, Daniel; Lie, Benedicte Alexandra; McLaren, Paul; Vyse, Timothy J.; Wijmenga, Cisca; Allanore, Yannick & Martin, Javier (2016). A genome-wide association study identifies risk alleles in plasminogen and P4HA2 associated with giant cell arteritis. American Journal of Human Genetics.  ISSN 0002-9297.  100(1), s 64- 74 . doi: 10.1016/j.ajhg.2016.11.013
  • Dominguez Valentin, Mev; Gras Navarro, Andrea; Rahman, Mohummad Aminur; Kumar, Surendra; Retière, Christèle; Ulvestad, Elling; Kristensen, Vessela N.; Lund-Johansen, Morten; Lie, Benedicte Alexandra; Enger, Per Øyvind; Njølstad, Gro; Kristoffersen, Einar Klæboe; Lie, Stein Atle & Chekenya, Martha (2016). Identification of a natural killer cell receptor allele that prolongs survival of cytomegalovirus-positive glioblastoma patients. Cancer Research.  ISSN 0008-5472.  76(18), s 5326- 5336 . doi: 10.1158/0008-5472.CAN-16-1162
  • Finkel, Terri H.; Li, Jin; Wei, Zhi; Wang, Wei; Zhang, Haitao; Behrens, Edward M.; Reuschel, Emma L.; Limou, Sophie; Wise, Carol; Punaro, Marilynn; Becker, Mara L.; Munro, Jane E.; Flatø, Berit; Førre, Øystein Thorleiv; Thompson, Susan D.; Langefeld, Carl D.; Glass, David N.; Glessner, Joseph T.; Kim, Cecilia E.; Frackelton, Edward; Shivers, Debra K.; Thomas, Kelly A.; Chiavacci, Rosetta M.; Hou, Cuiping; Xu, Kexiang; Snyder, James; Qiu, Haijun; Mentch, Frank; Wang, Kai; Winkler, Cheryl A.; Lie, Benedicte Alexandra; Ellis, Justine A. & Hakonarson, Hakon (2016). Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility. BMC Medical Genetics.  ISSN 1471-2350.  17(1) . doi: 10.1186/s12881-016-0285-3
  • Gabrielsen, Ingvild; Amundsen, Svanstrøm Silja; Helgeland, Hanna; Flåm, Siri Tennebø; Hatinoor, Nimo; Holm, Kristian; Viken, Marte K & Lie, Benedicte Alexandra (2016). Genetic risk variants for autoimmune diseases that influence gene expression in thymus. Human Molecular Genetics.  ISSN 0964-6906.  25(14), s 3117- 3124 . doi: 10.1093/hmg/ddw152 Vis sammendrag
  • Gabrielsen, Ingvild; Viken, Marte K; Amundsen, Svanstrøm Silja; Helgeland, Hanna; Holm, Kristian; Flåm, Siri Tennebø & Lie, Benedicte Alexandra (2016). Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus. Genes and Immunity.  ISSN 1466-4879.  17(7), s 406- 411 . doi: 10.1038/gene.2016.39
  • Gustavsen, Marte Wendel; Celius, Elisabeth Gulowsen; Winsvold, Bendik K S; Moen, Stine Marit; Nygaard, Gro Owren; Berg-Hansen, Pål; Lie, Benedicte Alexandra; Zwart, John-Anker & Harbo, Hanne Flinstad (2016). Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study. Multiple Sclerosis Journal, Experimental, Translational and Clinical.  ISSN 2055-2173.  2, s 1- 4 . doi: 10.1177/2055217316682976 Fulltekst i vitenarkiv.
  • Wang, Yunpeng; Bos, Steffan Daniel; Harbo, Hanne Flinstad; Thompson, Wesley K.; Schork, Andrew J.; Bettella, Francesco; Witoelar, Aree; Lie, Benedicte Alexandra; Li, Wen; McEvoy, Linda K.; Djurovic, Srdjan; Desikan, Rahul S.; Dale, Anders & Andreassen, Ole Andreas (2016). Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.. Multiple Sclerosis.  ISSN 1352-4585.  22(14), s 1783- 1793 . doi: 10.1177/1352458516635873
  • Andreassen, Ole Andreas; Desikan, Rahul S.; Wang, Yunpeng; Thompson, Wesley K.; Schork, Andrew J.; Zuber, Verena; Doncheva, Nadezhda T.; Ellinghaus, Eva; Albrecht, Mario; Mattingsdal, Morten; Franke, Andre; Lie, Benedicte Alexandra; Mills, Ian Geoffrey; Aukrust, Pål; McEvoy, Linda K.; Djurovic, Srdjan; Karlsen, Tom Hemming & Dale, Anders (2015). Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLoS ONE.  ISSN 1932-6203.  10:e 0123057(4) . doi: 10.1371/journal.pone.0123057 Fulltekst i vitenarkiv.
  • Andreassen, Ole Andreas; Harbo, Hanne Flinstad; Wang, Yunpeng; Thompson, WK; Schork, AJ; Mattingsdal, Morten; Zuber, Verena; Bettella, Franscesco; Ripke, S; Kelsoe, JR; Kendler, KS; O'Donovan, MC; Sklar, P; McEvoy, LK; Desikan, RS; Lie, Benedicte Alexandra; Djurovic, Srdjan & Dale, Anders M. (2015). Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Molecular Psychiatry.  ISSN 1359-4184.  20(2), s 207- 214 . doi: 10.1038/mp.2013.195 Fulltekst i vitenarkiv.
  • Bossini-Castillo, Lara; de Kovel, Carolien G.F.; Källberg, Henrik; van't Slot, Ruben; Italiaander, Annet; Coenen, Marieke J.H.; Tak, Paul P.; Posthumus, Marcel D.; Wijmenga, Cisca; Huizinga, Tom W.J.; van der Helm-van Mil, Annette H.M.; Stoeken-Rijsbergen, Gerrie; Rodríguez-Rodríguez, Luis; Balsa, Alejandro; González-Álvaro, Isidoro; González-Gay, Miguel A.; Gómez-Vaquero, Carmen; Franke, Barbara; Vermeulen, Sita H.; van der Horst-Bruinsma, Irene E.; Dijkmans, Ben A.C.; Wolbink, Gerrit Jan; Ophoff, Roel A.; Mæhlen, Marthe Thoresen; van Riel, Piet; Merriman, Marilyn; Klareskog, Lars; Lie, Benedicte Alexandra; Merriman, Tony; Crusius, J. Bart A.; Brouwer, Elisabeth; Martin, Javier; de Vries, Niek; Toes, René E.M.; Padyukov, Leonid & Koeleman, Bobby P.C. (2015). A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides. Annals of the Rheumatic Diseases.  ISSN 0003-4967.  74(e15) . doi: 10.1136/annrheumdis-2013-204591
  • Chiaroni-Clarke, Rachel C.; Li, Yun R.; Munro, Jane E.; Chavez, Raul A.; Scurrah, Katrina J.; Pezic, Angela; Akikusa, Jonathan D.; Allen, Roger C.; Piper, Susan E.; Becker, Mara L.; Thompson, Susan D.; Lie, Benedicte Alexandra; Flatø, Berit; Førre, Øystein Thorleiv; Punaro, Marilynn; Wise, Carol; Saffery, Richard; Finkel, Terri H.; Hakonarson, Hakon; Ponsonby, Anne-Louise & Ellis, Justine A. (2015). The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females. Genes and Immunity.  ISSN 1466-4879.  16(7), s 495- 498 . doi: 10.1038/gene.2015.32
  • Cortes, Adrian; Pulit, Sara L.; Leo, Paul J.; Pointon, Jenny J.; Robinson, Philip C.; Weisman, Michael H.; Ward, Michael; Gensler, Lianne S.; Zhou, Xiaodong; Garchon, Henri-Jean; Chiocchia, Gilles; Nossent, Johannes; Lie, Benedicte Alexandra; Førre, Øystein Thorleiv; Tuomilehto, Jaakko; Laiho, Kari; Bradbury, Linda A.; Elewaut, Dirk; Burgos-Vargas, Ruben; Stebbings, Simon; Appleton, Louise; Farrah, Claire; Lau, Jonathan; Haroon, Nigil; Mulero, Juan; Blanco, Francisco J.; González-Gay, Miguel A.; López-Larrea, Carlos; Bowness, Paul; Gaffney, Karl; Gaston, Hill; Gladman, Dafna D.; Rahman, Proton; Maksymowych, Walter P.; Crusius, J. Bart A.; van der Horst-Bruinsma, Irene E.; Valle-Oñate, Raphael; Romero-Sánchez, Consuelo; Myrnes, Inger; Pimentel-Santos, Fernando M.; Inman, Robert D.; Martin, Javier; Breban, Maxime; Wordsworth, Bryan Paul; Reveille, John D.; Evans, David M.; de Bakker, Paul I.W. & Brown, Matthew A. (2015). Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1. Nature Communications.  ISSN 2041-1723.  6 . doi: 10.1038/ncomms8146
  • Ellis, Justine A.; Scurrah, Katrina J.; Li, Yun R.; Ponsonby, Anne-Louise; Chavez, Raul A.; Pezic, Angela; Dwyer, Terence; Akikusa, Jonathan D.; Allen, Roger C.; Becker, Mara L.; Thompson, Susan D.; Lie, Benedicte Alexandra; Flatø, Berit; Førre, Øystein Thorleiv; Punaro, Marilynn; Wise, Carol; Finkel, Terri H.; Hakonarson, Hakon & Munro, Jane E. (2015). Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis. Journal of Steroid Biochemistry and Molecular Biology.  ISSN 0960-0760.  145, s 113- 120 . doi: 10.1016/j.jsbmb.2014.10.012
  • Flåm, Siri Tennebø; Gunnarsson, Ragnar; Garen, Torhild Oddveig; Lie, Benedicte Alexandra & Molberg, Øyvind (2015). The HLA profiles of mixed connective tissue disease differ distinctly from the profiles of clinically related connective tissue diseases. Rheumatology.  ISSN 1462-0324.  54(3), s 528- 535 . doi: 10.1093/rheumatology/keu310
  • Hov, Johannes Espolin Roksund; Zhong, Huanzi; Qin, Bincai; Anmarkrud, Jarl Andreas; Holm, Kristian; Franke, Andre; Lie, Benedicte Alexandra & Karlsen, Tom Hemming (2015). The influence of the autoimmunity-associated ancestral HLA haplotype AH8.1 on the human gut microbiota: A cross-sectional study. PLoS ONE.  ISSN 1932-6203.  10:e0133804(7) . doi: 10.1371/journal.pone.0133804
  • Li, Yun R.; Li, Jin; Zhao, Sihai D.; Bradfield, Jonathan P.; Mentch, Frank D.; Maggadóttir, Sólrún Melkorka; Hou, Cuiping; Abrams, Debra J.; Chang, Diana; Gao, Feng; Guo, Yiran; Wei, Zhi; Connolly, John J.; Cardinale, Christopher J.; Bakay, Marina; Glessner, Joseph T.; Li, Dong; Kao, Charlly; Thomas, Kelly A.; Qiu, Haijun; Chiavacci, Rosetta M.; Kim, Cecilia E.; Wang, Fengxiang; Snyder, James; Richie, Marylyn D.; Flatø, Berit; Førre, Øystein Thorleiv; Denson, Lee A.; Thompson, Susan D.; Becker, Mara L.; Guthery, Stephen L; Latiano, Anna; Perez, Elena; Resnick, Elena; Russell, Richard K.; Wilson, David C.; Silverberg, Mark S.; Annese, Vito; Lie, Benedicte Alexandra; Punaro, Marilynn; Dubinsky, Marla C.; Monos, Dimitri S.; Strisciuglio, Caterina; Staiano, Annamaria; Miele, Erasmo; Kugathasan, Subra; Ellis, Justine A.; Munro, Jane E.; Sullivan, Kathleen E.; Wise, Carol A.; Chapel, Helen; Cunningham-Rundles, Charlotte; Grant, Struan F.A.; Orange, Jordan S.; Sleiman, Patrick M.A.; Behrens, Edward M.; Griffiths, Anne M.; Satsangi, Jack; Finkel, Terri H.; Keinan, Alon; Prak, Eline T. Luning; Polychronakos, Constantin; Baldassano, Robert N.; Li, Hongzhe; Keating, Brendan J. & Hakonarson, Hakon (2015). Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nature Medicine.  ISSN 1078-8956.  21(9), s 1018- 1027 . doi: 10.1038/nm.3933
  • Li, Yun R.; Zhao, Sihai D.; Li, Jin; Bradfield, Jonathan P.; Mohebnasab, Maede; Steel, Laura; Kobie, Julie; Abrams, Debra J.; Mentch, Frank D.; Glessner, Joseph T.; Guo, Yiran; Wei, Zhi; Connolly, John J.; Cardinale, Christopher J.; Bakay, Marina; Li, Dong; Maggadóttir, Sólrún Melkorka; Thomas, Kelly A.; Qui, Haijun; Chiavacci, Rosetta M.; Kim, Cecilia E.; Wang, Fengxiang; Snyder, James; Flatø, Berit; Førre, Øystein Thorleiv; Denson, Lee A.; Thompson, Susan D.; Becker, Mara L.; Guthery, Stephen L.; Latiano, Anna; Perez, Elena; Resnick, Elena; Strisciuglio, Caterina; Staiano, Annamaria; Miele, Erasmo; Silverberg, Mark S.; Lie, Benedicte Alexandra; Punaro, Marilynn; Russell, Richard K.; Wilson, David C.; Dubinsky, Marla C.; Monos, Dimitri S.; Annese, Vito; Munro, Jane E.; Wise, Carol; Chapel, Helen; Cunningham-Rundles, Charlotte; Orange, Jordan S.; Behrens, Edward M.; Sullivan, Kathleen E.; Kugathasan, Subra; Griffiths, Anne M.; Satsangi, Jack; Grant, Struan F.A.; Sleiman, Patrick M.A.; Finkel, Terri H.; Polychronakos, Constantin; Baldassano, Robert N.; Luning Prak, Eline T.; Ellis, Justine A.; Li, Hongzhe; Keating, Brendan J. & Hakonarson, Hakon (2015). Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nature Communications.  ISSN 2041-1723.  6:8442 . doi: 10.1038/ncomms9442
  • Mæhlen, Marthe Thoresen; Olsen, Inge Christoffer; Kulle Andreassen, Bettina; Viken, Marte K; Jiang, Xia; Alfredsson, Lars; Källberg, Henrik; Brynedal, Boel; Kurreeman, Fina; Daha, Nina A.; Toes, René E.M.; Zhernakova, Alexandra; Gurierrez-Achury, Javier; de Bakker, Paul L. W.; Martin, Javier; Teruel, Maria; Gonzalez-Gay, Miguel A.; Rodríguez-Rodríguez, Luis; Balsa, Alejandro; Uhlig, Till; Kvien, Tore Kristian & Lie, Benedicte Alexandra (2015). Genetic risk scores and number of autoantibodies in patients with rheumatoid arthritis. Annals of the Rheumatic Diseases.  ISSN 0003-4967.  74(4), s 762- 768 . doi: 10.1136/annrheumdis-2013-204173
  • Omair, Ahmad; Mannion, Anne F.; Holden, Marit; Fairbank, Jeremy; Lie, Benedicte Alexandra; Hägg, Olle; Fritzell, Peter & Brox, Jens Ivar (2015). Catechol-O-methyltransferase (COMT) gene polymorphisms are associated with baseline disability but not long-term treatment outcome in patients with chronic low back pain. European spine journal.  ISSN 0940-6719.  24(11), s 2425- 2431 . doi: 10.1007/s00586-015-3866-5 Vis sammendrag
  • Seldin, Michael F.; Alkhairy, Omar K; Lee, Annette T.; Lamb, Janine; Sussman, Jon; Pirskanen-Matell, Ritva; Piehl, Fredrik; Verschuuren, Jan J. G. M; Kostera-Pruszczyk, Anna; Szczudlik, Piotr; McKee, David; Maniaol, Angelina; Harbo, Hanne Flinstad; Lie, Benedicte Alexandra; Melms, Arthur; Garchon, Henri-Jean; Willcox, Nicholas; Gregersen, Peter K & Hammarstrom, Lennart (2015). Genome-wide association study of late-onset myasthenia gravis: Confirmation of TNFRSF11A and identification of ZBTB10 and three distinct HLA associations. Molecular medicine (Cambridge, Mass. Print).  ISSN 1076-1551.  21, s 769- 781 . doi: 10.2119/molmed.2015.00232 Vis sammendrag
  • Amundsen, Svanstrøm Silja; Viken, Marte K; Sollid, Ludvig Magne & Lie, Benedicte Alexandra (2014). Coeliac disease-associated polymorphisms influence thymic gene expression. Genes and Immunity.  ISSN 1466-4879.  15(6), s 355- 360 . doi: 10.1038/gene.2014.26
  • Andersen, Ina Marie Riise; Tengesdal, Guro; Lie, Benedicte Alexandra; Boberg, Kirsten Muri; Karlsen, Tom Hemming & Hov, Johannes Espolin Roksund (2014). Effects of Coffee Consumption, Smoking, and Hormones on Risk for Primary Sclerosing Cholangitis. Clinical Gastroenterology and Hepatology.  ISSN 1542-3565.  12(6), s 1019- 1028 . doi: 10.1016/j.cgh.2013.09.024
  • Avidan, Nili; Panse, Rozen Le; Harbo, Hanne Flinstad; Bernasconi, Pia; Poulas, Konstantinos; Ginzburg, Elizabeta; Cavalcante, Paola; Colleoni, Lara; Baggi, Fulvio; Antozzi, Carlo; Truffault, Frederique; Horn-Saban, Shirley; Poschel, Simone; Zagoriti, Zoi; Maniaol, Angelina; Lie, Benedicte Alexandra; Bernard, Isabelle; Saoudi, Abdelhadi; Illes, Zsolt; Pons, Carlos Casasnovas; Melms, Arthur; Tzartos, Socrates; Willcox, Nicholas; Kostera-Pruszczyk, Anna; Tallaksen, Chantal; Mantegazza, Renato; Berrih-Aknin, S. & Miller, Ariel (2014). VAV1 and BAFF, via NFκB pathway, are genetic risk factors for myasthenia gravis. Annals of clinical and translational neurology.  ISSN 2328-9503.  1(5), s 329- 339 . doi: 10.1002/acn3.51
  • Gustavsen, Marte Wendel; Page, Christian; Moen, Stine Marit; Bjølgerud, Anja; Berg-Hansen, Pål; Nygaard, Gro Owren; Sandvik, Leiv; Lie, Benedicte Alexandra; Celius, Elisabeth Gulowsen & Harbo, Hanne Flinstad (2014). Environmental exposures and the risk of multiple sclerosis investigated in a Norwegian case-control study. BMC Neurology.  ISSN 1471-2377.  14(1) . doi: 10.1186/s12883-014-0196-x Fulltekst i vitenarkiv.
  • Gustavsen, Marte Wendel; Viken, Marte K; Celius, Elisabeth Gulowsen; Berge, Tone; Mero, Inger-Lise; Berg-Hansen, Pål; Aarseth, Jan Harald; Myhr, Kjell-Morten; Søndergaard, Helle Bach; Sellebjerg, Finn; Oturai, Annette Bang; Hillert, Jan; Alfredsson, Lars; Olsson, Tomas; Kockum, Ingrid; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2014). Oligoclonal band phenotypes in MS differ in their HLA class II association, while specific KIR ligands at HLA class I show association to MS in general. Journal of Neuroimmunology.  ISSN 0165-5728.  274(1-2), s 174- 179 . doi: 10.1016/j.jneuroim.2014.06.024
  • Moreno-Mayar, J. Victor; Rasmussen, Simon; Seguin-Orlando, Andaine; Rasmussen, Morten; Liang, Mason; Flåm, Siri Tennebø; Lie, Benedicte Alexandra; Gilfillan, Gregor Duncan; Nielsen, Rasmus; Thorsby, Erik; Willerslev, Eske & Malaspinas, Anna-Sapfo (2014). Genome-wide ancestry patterns in rapanui suggest pre-european admixture with native americans. Current Biology.  ISSN 0960-9822.  24(21), s 2518- 2525 . doi: 10.1016/j.cub.2014.09.057
  • Næss, Sigrid; Björnsson, Einar; Anmarkrud, Jarl Andreas; Al Mamari, Said; Juran, Brian D.; Lazaridis, Konstantinos N.; Chapman, Roger W.; Annika, Bergquist; Melum, Espen; Marsh, Steven G.E.; Schrumpf, Erik; Lie, Benedicte Alexandra; Boberg, Kirsten Muri; Karlsen, Tom Hemming & Hov, Johannes Espolin Roksund (2014). Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease. Liver international (Print).  ISSN 1478-3223.  34(10), s 1488- 1495 . doi: 10.1111/liv.12492
  • Næss, Sigrid; Lie, Benedicte Alexandra; Melum, Espen; Olsson, Marita; Hov, Johannes Espolin Roksund; Croucher, PJP; Hampe, Jochen; Thorsby, Erik; Bergquist, Annika; Traherne, James A.; Schrumpf, Erik; Boberg, Kirsten Muri; Schreiber, Stefan; Franke, Andre & Karlsen, Tom Hemming (2014). Refinement of the MHC risk map in a Scandinavian primary sclerosing cholangitis population. PLoS ONE.  ISSN 1932-6203.  9:e0114486(12) . doi: 10.1371/journal.pone.0114486
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  • Mero, Inger-Lise; Ban, Maria; Lorentzen, Åslaug Rudjord; SMESTAD, CATHRINE; Celius, Elisabeth Gulowsen; Sæther, Hanne Skarpodde; Saeedi, Haleh; Viken, Marte K; Skinningsrud, Beate; Undlien, Dag Erik; Aarseth, Jan Harald; Myhr, Kjell-Morten; Granum, Stine; Spurkland, Anne; Sawcer, Stephen; Compston, Alastair; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2011). Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus. Genes and Immunity.  ISSN 1466-4879.  12(3), s 191- 198 . doi: 10.1038/gene.2010.59
  • Mæhlen, Marthe Thoresen; Nordang, Gry Beate Namløs; Syversen, Silje Watterdal; van der Heijde, Desirée; Kvien, Tore Kristian; Uhlig, Till & Lie, Benedicte Alexandra (2011). FCRL3-169C/C Genotype Is Associated with Anti-citrullinated Protein Antibody-positive Rheumatoid Arthritis and with Radiographic Progression. Journal of Rheumatology.  ISSN 0315-162X.  38(11), s 2329- 2335 . doi: 10.3899/jrheum.110489
  • Rodríguez-Rodríguez, L; Wan Taib, WR; Topless, R; Steer, S; González-Escribano, MF; Balsa, A; Pascual-Salcedo, D; Gonzalez-Gay, MA; Raya, E; Fernandez-Gutierrez, B; González-Álvaro, I; Bottini, N; Witte, T; Viken, Marte K; Coenen, MJ; van Riel, PL; Franke, B; den Heijer, M; Radstake, TR; Wordsworth, P.; Lie, Benedicte Alexandra; Merriman, TR & Martin, J (2011). The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in caucasian case-control samples. Arthritis and Rheumatism.  ISSN 0004-3591.  63(2), s 365- 372 . doi: 10.1002/art.30145
  • Skinningsrud, Beate; Lie, Benedicte Alexandra; Lavant, Ewa; Carlson, Joyce A.; Erlich, Henry; Akselsen, Hanne Elisabeth; Gervin, Kristina; Wolff, Anette Susanne Bøe; Erichsen, Eva Martina Moter; Løvås, Kristian; Husebye, Eystein Sverre & Undlien, Dag Erik (2011). Multiple loci in the HLA complex are associated with Addison's Disease. Journal of Clinical Endocrinology and Metabolism.  ISSN 0021-972X.  96(10), s E1703- E1708 . doi: 10.1210/jc.2011-0645
  • Zaiss, DM; Bekker, CP; Gröne, A; Lie, Benedicte Alexandra & Sijts, AJ (2011). Proteasome immunosubunits protect against the development of CD8 T cell-mediated autoimmune diseases. Journal of Immunology.  ISSN 0022-1767.  187(5), s 2302- 2309 . doi: 10.4049/jimmunol.1101003
  • Syversen, Silje Watterdal; van der Heijde, D; Landewé, Robert; Lie, Benedicte Alexandra; Ødegård, Sigrid; Uhlig, Till; Gaarder, Per Ivar Brachel; Kvien, Tore Kristian & Goll, Guro Løvik (2010). Prediction of radiographic progression in rheumatoid arthritis and the role of antibodies against mutated citrullinated vimentin: results from a 10-year prospective study. Annals of the Rheumatic Diseases.  ISSN 0003-4967.  69(2), s 345- 351 . doi: 10.1136/ard.2009.113092
  • Amundsen, Svanstrøm Silja; Rundberg, J; Adamovic, S; Gudjònsdòttir, Audur H; Ascher, H; Ek, Johan; Nilsson, S; Lie, Benedicte Alexandra; Naluai, Å.T. & Sollid, Ludvig Magne (2010). Four novel coeliac disease regions replicated in an association study of a Swedish-Norwegian family cohort. Genes and Immunity.  ISSN 1466-4879.  11(1), s 79- 86 . doi: 10.1038/gene.2009.67
  • Bowlus, Christopher L.; Li, Chin-Shang; Karlsen, Tom Hemming; Lie, Benedicte Alexandra & Selmi, Carlo (2010). Primary Sclerosing Cholangitis in Genetically Diverse Populations Listed for Liver Transplantation: Unique Clinical and Human Leukocyte Antigen Associations. Liver transplantation.  ISSN 1527-6465.  16(11), s 1324- 1330 . doi: 10.1002/lt.22161
  • Harbo, Hanne Flinstad; Riccio, Maria Elena; Lorentzen, Åslaug Rudjord; Utsi, Egil; Myhr, Kjell-Morten; Mellgren, Svein Ivar; Flåm, Siri T.; Thorsby, Erik; Sanchez-Mazas, Alicia & Lie, Benedicte A (2010). Norwegian Sami differs significantly from other Norwegians according to their HLA profile. Tissue Antigens.  ISSN 0001-2815.  75(3), s 207- 217 . doi: 10.1111/j.1399-0039.2009.01425.x
  • Hov, Johannes Espolin Roksund; Keitel, V; Lærdahl, Jon Kristen; Spomer, L; Ellinghaus, E; ElSharawy, A; Melum, Espen; Boberg, Kirsten Muri; Manke, T; Balschun, T; Schramm, C; Bergquist, A; Weismuller, T; Gotthardt, D; Rust, C; Henckaerts, L; Onnie, CM; Weersma, RK; Sterneck, M; Teufel, A; Runz, H; Stiehl, A; Ponsioen, CY; Wijmenga, C; Vatn, Morten H; Stokkers, PCF; Vermeire, S; Mathew, CG; Lie, Benedicte Alexandra; Beuers, U; Manns, MP; Schreiber, S; Schrumpf, Erik; Haussinger, D; Franke, A & Karlsen, Tom Hemming (2010). Mutational Characterization of the Bile Acid Receptor TGR5 in Primary Sclerosing Cholangitis. PLoS ONE.  ISSN 1932-6203.  5(8) . doi: 10.1371/journal.pone.0012403
  • Karlsen, Tom Hemming; Franke, Andre; Melum, Espen; Kaser, Arthur; Hov, Johannes Espolin Roksund; Balschun, Tobias; Lie, Benedicte Alexandra; Bergquist, Annika; Schramm, Christoph; Weismüller, Tobias J.; Gotthardt, Daniel; Rust, Christian; Philipp, Eva E.R.; Fritz, Teresa; Henckaerts, Liesbet; Weersma, Rinse K.; Stokkers, Pieter C.F.; Ponsioen, Cyriel Y.; Wijmenga, Cisca; Sterneck, Martina; Nothnagel, Michael; Hampe, Jochen; Teufel, Andreas; Runz, Heiko; Rosenstiel, Philip; Stiehl, Adolf; Vermeire, Severine; Beuers, Ulrich; Manns, Michael P.; Schrumpf, Erik; Boberg, Kirsten Muri & Schreiber, Stefan (2010). Genome-Wide Association Analysis in Primary Sclerosing Cholangitis. Gastroenterology.  ISSN 0016-5085.  138(3), s 1102- 1111 . doi: 10.1053/j.gastro.2009.11.046
  • Link, Jenny; Lorentzen, Åslaug Rudjord; Kochum, Ingrid; Duvefelt, Kristina; Lie, Benedicte Alexandra; Celius, Elisabeth Gulowsen; Harbo, Hanne Flinstad; Hillert, Jan & Brynedal, Boel (2010). Two HLA class I genes independently associated with multiple sclerosis. Journal of Neuroimmunology.  ISSN 0165-5728.  226(1-2), s 172- 176 . doi: 10.1016/j.jneuroim.2010.07.006
  • Lorentzen, Åslaug Rudjord; Melum, Espen; Ellinghaus, Eva; Smestad, Cathrine; Mero, Inger-Lise; Aarseth, Jan Harald; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Lie, Benedicte Alexandra; Karlsen, Tom Hemming; Franke, Andre & Harbo, Hanne Flinstad (2010). Association to the Glypican-5 gene in multiple sclerosis. Journal of Neuroimmunology.  ISSN 0165-5728.  226(1-2), s 194- 197 . doi: 10.1016/j.jneuroim.2010.07.003

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  • Lande, Asgeir; Andersen, Irene; Egeland, Torstein; Lie, Benedicte Alexandra & Viken, Marte K (2018). HLA -A, -C, -B, -DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in 4514 healthy Norwegians. Human Immunology.  ISSN 0198-8859.  79(7), s 527- 529 . doi: 10.1016/j.humimm.2018.04.012
  • Gustavsen, Marte Wendel; Celius, Elisabeth Gulowsen; Moen, Stine Marit; Bjølgerud, Anja; Berg-Hansen, Pål; Nygaard, Gro Owren; Sandvik, Leiv; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2015). No association between multiple sclerosis and periodontitis after adjusting for smoking habits. European Journal of Neurology.  ISSN 1351-5101.  22(3), s 588- 590 . doi: 10.1111/ene.12520
  • Robinson, Philip C.; Costello, Mary-Ellen; Leo, Paul; Bradbury, Linda A.; Hollis, Kelly; Cortes, Adrian; Lee, Seunghun; Joo, Kyung Bin; Shim, Seung-Cheol; Weisman, Michael; Ward, Michael; Zhou, Xiaodong; Garchon, Henri-Jean; Chiocchia, Gilles; Nossent, Johannes; Lie, Benedicte Alexandra; Førre, Øystein Thorleiv; Tuomilehto, Jaakko; Laiho, Kari; Jiang, Lei; Liu, Yu; Wu, Xin; Elewaut, Dirk; Burgos-Vargas, Ruben; Gensler, Lianne S.; Stebbings, Simon; Haroon, Nigil; Mulero, Juan; Fernandez-Sueiro, Jose Luis; González-Gay, Miguel A.; Lopez-Larrea, Carlos; Bowness, Paul; Gafney, Karl; Gaston, John S. Hill; Gladman, Dafna D.; Rahman, Proton; Maksymowych, Walter P.; Xu, Huji; Van Der Horst-Bruinsma, Irene E.; Chou, Chung-Tei; Valle-Oñate, Raphael; Romero-Sánchez, María Consuelo; Myrnes, Inger; Pimentel-Santos, Fernando M.; Inman, Robert D.; Martin, Javier; Breban, Maxime; Evans, David; Reveille, John D.; Kim, Tae-Hwan; Wordsworth, B. Paul & Brown, Matthew A. (2015). ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients. Annals of the Rheumatic Diseases.  ISSN 0003-4967.  74(8), s 1627- 1629 . doi: 10.1136/annrheumdis-2015-207416
  • Sanchez-Mazas, Alicia; Buhler, Stéphane; Bekmane, Uma; Buus, Søren; Claas, Frans H.J.; Dormoy, Anne; Dubois, Valerie; Eberhard, Hans-Peter; Eglite, Jelena; Eliaou, Jean-Francois; Fischer, Gottfried F.; Gonzalez-Galarza, Faviel; Grubic, Zorana; Ivanova, Milena; Lie, Benedicte Alexandra; Ligeiro, Dário; Little, Ann-Margaret; Lokki, Marja-Liisa; Marsh, Stephen; da Silva, Berta Martins; Martorell, Jaume; Mendona, Denisa; Middleton, Derek; Mueller, Carlheinz R.; Voniatis, Constantia Papaioannou; Papasteriades, Chryssa; Poli, Francesca; Riccio, ME; Spyropoulou-Vlachou, Maria; Sulcebe, Genc; Tiercy, Jean-Marie; Tonks, Susan; Tordai, Attila; Nevessignsky, Michel Toungouz; Vangenot, Christelle; van Walraven, Anne-Marie; Vidan-Jeras, Blanka; Viken, Marte K & Nunes, José Manuel de Abreu (2013). HLA-NET: A REAL EXAMPLE OF 'NETWORKING IN IMMUNOGENETICS'. Tissue Antigens.  ISSN 0001-2815.  81(5), s 300- 301
  • Tinholt, Mari; Viken, MK; Borresen-Dale, AL; Kristensen, V; Karesen, R; Schlichting, E; Oystein, G; Lie, Benedicte Alexandra; Dahm, Anders Erik A; Skretting, Grethe; Sandset, Per Morten & Iversen, Nina (2013). The link between the hemostatic system and cancer: A genotype-phenotype study in breast cancer patients. Thrombosis Research.  ISSN 0049-3848.  131, s S75- S76
  • Berge, Tone; Leikfoss, Ingvild Sørum; Spurkland, Anne; Lie, Benedicte Alexandra & Harbo, Hanne Flinstad (2012). Multiple sclerosis-associated single nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in thymic tissue.
  • Chen-Xu, Michael; Topless, Ruth; McKinney, Cushla; Merriman, Marilyn E.; Phipps-Green, Amanda; Dalbeth, Nicola; Gow, Peter J.; Harrison, Andrew A.; Highton, John; Jones, Peter B; Nissen, Michael; Smith, Malcolm D.; van Rij, André; Jones, Greg T.; Rodríguez-Rodríguez, Luis; Fernandez-Gutierrez, Benjamin; Teruel, Maria; Balsa, Alejandro; Pascual-Salcedo, Dora; Ortiz, Ana M.; Gonzalez-Gay, Miguel A.; Steer, Sophia; Mæhlen, Marthe Thoresen; Lie, Benedicte Alexandra; Wordsworth, B. Paul; Stamp, Lisa K.; Martin, Javier & Merriman, Tony R. (2012). Replication of association of the interleukin 23 receptor rs1343151 variant with rheumatoid arthritis in Caucasian sample sets. Annals of the Rheumatic Diseases.  ISSN 0003-4967.  71(1), s 155- U1 . doi: 10.1136/annrheumdis-2011-200591
  • Leikfoss, Ingvild S; Mero, Inger-Lise; Dahle, Maria Krudtaa; Lie, Benedicte Alexandra; Harbo, Hanne Flinstad; Spurkland, Anne & Berge, Tone (2012). Multiple Sclerosis Associated Single Nucleotide Polymorphisms in CLEC16A Correlate with Reduced SOCS1 and DEXI Expression in Thymic Samples. Scandinavian Journal of Immunology.  ISSN 0300-9475.  76(2), s 196- 196
  • Merriman, Tony R.; Dalbeth, Nicola; Harrison, Andrew; Highton, John; Stamp, Lisa K.; Smith, Malcolm D.; Lie, Benedicte Alexandra; Kvien, Tore Kristian; Radstake, Timothy R.D.J.; Coenen, Marieke J.H.; Franke, Barbara; Broen, Jasper; van Riel, Piet; Barrera, Pilar; Steer, Sophia; Merriman, Marilyn E.; Phipps-Green, Amanda; Topless, Ruth; Zamanpoor, Mansour & Tain, WRW (2012). The Sex-Determining Region Y Box 6 Locus: Shared Genetic Susceptibility Between Rheumatoid Arthritis and Psychotic Disorder. Arthritis and Rheumatism.  ISSN 0004-3591.  64(10), s S505- S506
  • Naess, Sigrid; Anmarkrud, Jarl Andreas; Björnsson, Einar; Al Mamari, Said; Juran, Brian D.; Lazaridis, Konstantios N; Chapman, Roger W.; Bergquist, Annika; Schrumpf, Erik; Lie, Benedicte Alexandra; Boberg, Kirsten Muri; Karlsen, Tom Hemming & Hov, Johannes Espolin Roksund (2012). HLA associations in small-duct compared with large-duct primary sclerosing cholangitis. Hepatology.  ISSN 0270-9139.  56, s 1134A- 1134A
  • Tautz, Lutz; Vang, Torkel; Liu, Wallace; Delacroix, Laurence; Wu, Shuangding; Vasile, Stefan; Dahl, Russell; Yang, Li; Musumeci, Lucia; Francis, Dana; Landskron, Johannes; Tasken, Kjetil; Tremblay, Michel L.; Lie, Benedicte Alexandra; Page, Rebecca; Mustelin, Tomas; Rahmouni, Souad & Rickert, Robert C. (2012). Dynamic interaction between lymphoid tyrosine phosphatase and C-terminal Src kinase controls T cell activation. The FASEB Journal.  ISSN 0892-6638.  26
  • Tengesdal, Guro; Lie, Benedicte Alexandra; Boberg, Kirsten Muri; Karlsen, Tom Hemming & Hov, Johannes Espolin Roksund (2012). Survey of nongenetic risk factors suggests that tobacco exposure, coffee consumption, the use of oral contraception and the number of pregnancies could affect disease risk or presentation of primary sclerosing cholangitis. Hepatology.  ISSN 0270-9139.  56, s 301A- 301A
  • Viken, Marte K; Flåm, Siri Tennebø; Sollid, Ludvig Magne; Skrivarhaug, Torild; Dahl-Jørgensen, Knut & Lie, Benedicte Alexandra (2012). STUDY OF THE HLA-DRB1 AND-DQB1 GENES IN PATIENTS WITH COEXISTING TYPE 1 DIABETES AND CELIAC DISEASE. Tissue Antigens.  ISSN 0001-2815.  79(6), s 584- 584
  • Zaiss, Dietmar; Bekker, Cornelis; Grne, Andrea; Lie, Benedicte Alexandra & Sijts, Alice (2012). Proteasome immunosubunits protect against the development of CD8 T-cell-mediated autoimmune diseases. Molecular Immunology.  ISSN 0161-5890.  51(1), s 30- 31 . doi: 10.1016/j.molimm.2012.02.084
  • Eike, Morten Christoph; Skinningsrud, Beate; Lie, Benedicte Alexandra; Husebye, Eystein Sverre & Undlien, Dag Erik (2011). No association with RFX, CCR5 or CD226 polymorphisms in Norwegian Addison’s disease patients. Vis sammendrag
  • Link, J.; Kockum, I.; Lorentzen, Åslaug Rudjord; Lie, Benedicte Alexandra; Celius, Elisabeth Gulowsen; Schaffer, M.; Brynedal, B.; Harbo, Hanne Flinstad & Hillert, J. (2011). Investigation of HLA genes in multiple sclerosis in Scandinavia. Journal of Neurology.  ISSN 0340-5354.  258, s 196- 196
  • Sørum, Ingvild; Mero, Inger-Lise; Gustavsen, Marte Wendel; Muggerud, Aslaug; Sæther, Hanne Skarpodde; Lie, Benedicte Alexandra; Spurkland, Anne; Berge, Tone & Harbo, Hanne Flinstad (2011). Molecular Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A. Scandinavian Journal of Immunology.  ISSN 0300-9475.  73(4), s 377- 377
  • Eike, Morten Christoph; Skinningsrud, Beate; Kvien, Tore Kristian; Stormyr, Alice; Undlien, Dag Erik & Lie, Benedicte Alexandra (2010). Support for involvement of CIITA gene variants in rheumatoid arthritis. Vis sammendrag
  • Lorentzen, Åslaug Rudjord; Melum, Espen; Buchert, Eva; SMESTAD, CATHRINE; Mero, Inger-Lise; Aarseth, Jan Harald; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Lie, Benedicte Alexandra; Karlsen, Tom Hemming; Franke, Andre & Harbo, Hanne Flinstad (2010). Trend of association to the Glypican 5 gene region to multiple sclerosis. European Journal of Neurology.  ISSN 1351-5101.  17, s 221- 221

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Publisert 13. apr. 2011 11:41 - Sist endret 20. okt. 2016 13:21