Lars Eide

• Yang, Mingyi; Lin, Xiaolin; Segers, Filip; Suganthan, Rajikala; Hildrestrand, Gunn Annette; Rinholm, Johanne Egge; Aas, Per Arne; Sousa, Mirta; Holm, Sverre; Bolstad, Nils; Warren, David; Berge, Rolf Kristian; Johansen, Rune Forstrøm; Yndestad, Arne; Kristiansen, Elise; Klungland, Arne; Gomez, Luisa Fernanda Luna; Eide, Lars; Halvorsen, Bente; Aukrust, Pål & Bjørås, Magnar (2020). OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation. Cell reports.  ISSN 2211-1247.  30(12), s 4165- 4178 . doi: 10.1016/j.celrep.2020.02.063 Fulltekst i vitenarkiv.
• Rodinová, Marie; Křížová, Jana; Štufková, Hana; Bohuslavová, Božena; Askeland, Georgina; Dosoudilova, Zaneta; Juhás, Štefan; Juhásová, Jana; Ellederová, Zdenka; Zeman, Jiří; Eide, Lars; Motlík, Jan & Hansíková, Hana (2019). Deterioration of mitochondrial bioenergetics and ultrastructure impairment in skeletal muscle of a transgenic minipig model in the early stages of Huntington's disease. Disease Models and Mechanisms.  ISSN 1754-8403.  12:dmm038737(7), s 1- 13 . doi: 10.1242/dmm.038737 Fulltekst i vitenarkiv.
• Smatlikova, Petra; Askeland, Georgina; Vaskovicova, Michaela; Klima, Jiri; Motlik, Jan; Eide, Lars & Ellederova, Zdenka (2019). Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin. Neurodegenerative Diseases.  ISSN 1660-2854.  19(1), s 22- 34 . doi: 10.1159/000500091 Fulltekst i vitenarkiv.
• Askeland, Georgina; Dosoudilova, Zaneta; Rodinova, Marie; Klempir, Jiri; Liskova, Irena; Kusnierczyk, Anna; Bjørås, Magnar; Nesse, Gaute; Klungland, Arne; Hansikova, Hana & Eide, Lars (2018). Increased nuclear DNA damage precedes mitochondrial dysfunction in peripheral blood mononuclear cells from Huntington's disease patients. Scientific Reports.  ISSN 2045-2322.  8(1) . doi: 10.1038/s41598-018-27985-y Fulltekst i vitenarkiv.
• Askeland, Georgina; Rodinova, Marie; Štufková, Hana; Dosoudilova, Zaneta; Baxa, Monika; Smatlikova, Petra; Bohuslavova, Bozena; Klempir, Jiri; Nguyen, The Duong; Kuśnierczyk, Anna; Bjørås, Magnar; Klungland, Arne; Hansikova, Hana; Ellederova, Zdenka & Eide, Lars (2018). A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies. Disease Models and Mechanisms.  ISSN 1754-8403.  11(10) . doi: 10.1242/dmm.035949 Fulltekst i vitenarkiv.
• Bousquet, Paula; Meltzer, Sebastian; Sønstevold, Linda; Esbensen, Qin Ying; Dueland, Svein; Flatmark, Kjersti; Sitter, Beathe; Bathen, Tone Frost; Seierstad, Therese; Redalen, Kathrine; Eide, Lars & Ree, Anne Hansen (2018). Markers of mitochondrial metabolism in tumor hypoxia, systemic inflammation, and adverse outcome of rectal cancer. Translational Oncology.  ISSN 1944-7124.  12(1), s 76- 83 . doi: 10.1016/j.tranon.2018.09.010 Fulltekst i vitenarkiv.
• Kassahun, Henok; Sengupta, Tanima; Schiavi, Alfonso; Maglioni, Silvia; Skjeldam, Hanne Kim; Arczewska, Katarzyna; Brockway, Nicole L; Estes, Suzanne; Eide, Lars; Ventura, Natascia & Nilsen, Hilde Loge (2018). Constitutive MAP-kinase activation suppresses germline apoptosis in NTH-1 DNA glycosylase deficient C. elegans. DNA Repair.  ISSN 1568-7864.  61, s 46- 55 . doi: 10.1016/j.dnarep.2017.11.009 Fulltekst i vitenarkiv.
• Scheffler, Katja; Rachek, Lyudmila; You, Panpan; Rowe, Alexander D.; Wang, Wei; Kuśnierczyk, Anna; Kittelsen, Lene Svendsen; Bjørås, Magnar & Eide, Lars (2018). 8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis. DNA Repair.  ISSN 1568-7864.  61, s 56- 62 . doi: 10.1016/j.dnarep.2017.11.008 Fulltekst i vitenarkiv.
• Jackson, Catherine; Reppe, Sjur; Eidet, Jon Roger; Eide, Lars; Tønseth, Kim Alexander; Bergersen, Linda Hildegard; Dartt, Darlene A.; Griffith, May & Utheim, Tor Paaske (2017). Optimization of storage temperature for Retention of Undifferentiated cell character of cultured human epidermal cell sheets. Scientific Reports.  ISSN 2045-2322.  7:8206, s 1- 14 . doi: 10.1038/s41598-017-08586-7
• Li, Xiaoran; Lu, Jie; Kan, Quancheng; Li, Xiaoli; Fan, Qiong; Li, Yaqing; Huang, Ruixia; Slipicevic, Ana; Dong, Phuc Hiep; Eide, Lars; Wang, Junbai; Zhang, Hongquan; Berge, Viktor; Goscinski, Mariusz Adam; Kvalheim, Gunnar; Nesland, Jahn M & Suo, Zhenhe (2017). Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells. Scientific Reports.  ISSN 2045-2322.  7:5081, s 1- 20 . doi: 10.1038/s41598-017-05086-6
• Pawar, Tina; Bjørås, Magnar; Klungland, Arne & Eide, Lars (2017). Metabolism and DNA repair shape a specific modification pattern in mitochondrial DNA.. Mitochondrion (Amsterdam. Print).  ISSN 1567-7249.  40, s 16- 28 . doi: 10.1016/j.mito.2017.09.002 Fulltekst i vitenarkiv.
• Pawar, Tina & Eide, Lars (2017). Pitfalls in mitochondrial epigenetics. Mitochondrial DNA. Part A, DNA Mapping, Sequencing, and Analysis.  ISSN 2470-1394.  28(5), s 762- 768 . doi: 10.1080/24701394.2016.1180514 Fulltekst i vitenarkiv.
• Sokolova, Marina; Vinge, Leif Erik; Alfsnes, Katrine; Olsen, Maria Belland; Eide, Lars; Kaasbøll, Ole Jørgen; Attramadal, Håvard; Torp, May-Kristin; Fosshaug, Linn Elisabeth Lillerud; Rashidi, Azita; Lien, Egil; Finsen, Alexandra; Sandanger, Øystein; Aukrust, Pål; Ranheim, Trine & Yndestad, Arne (2017). Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids.  ISSN 1388-1981.  1862(2), s 234- 245 . doi: 10.1016/j.bbalip.2016.11.003
• Distante, Sonia; Eikeland, Joakim; Pawar, Tina; Skinnes, Ragnhild; Høie, Kari; You, Panpan; Mørkrid, Lars & Eide, Lars (2016). Blood removal therapy in hereditary hemochromatosis induces a stress response resulting in improved genome integrity. Transfusion.  ISSN 0041-1132.  56(6), s 1435- 1441 . doi: 10.1111/trf.13588
• Khuu, Cuong; Sehic, Amer; Eide, Lars & Osmundsen, Harald (2016). Anti-proliferative properties of miR-20b and miR-363 from the miR-106a-363 cluster on human carcinoma cells. MicroRNA.  ISSN 2211-5366. . doi: 10.2174/2211536605666160322151813
• Li, Xiaoran; Zhong, Yali; Lu, Jie; Axcrona, Karol; Eide, Lars; Syljuåsen, Randi G.; Qian, Peng; Wang, Junbai; Zhang, Hongquan; Goscinski, Mariusz Adam; Kvalheim, Gunnar; Nesland, Jahn M & Suo, Zhenhe (2016). MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features. OncoTarget.  ISSN 1949-2553.  7(26), s 40297- 40313 . doi: 10.18632/oncotarget.9610 Fulltekst i vitenarkiv.
• Skarpengland, Tonje; Dahl, Tuva Børresdatter; Skjelland, Mona; Scheffler, Katja; Sousa, Mirta; Gregersen, Ida; Kusnierczyk, Anna; Sharma, Animesh; Slupphaug, Geir; Eide, Lars; Segers, Filip; Skagen, Karolina Ryeng; Dahl, Christen Peder; Russell, David; Folkersen, Lasse; Krohg-Sørensen, Kirsten; Holm, Sverre; Bjørås, Magnar; Aukrust, Pål & Halvorsen, Bente (2016). Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA. Free Radical Biology & Medicine.  ISSN 0891-5849.  97, s 386- 397 . doi: 10.1016/j.freeradbiomed.2016.07.001
• Skarpengland, Tonje; Holm, Sverre; Scheffler, Katja; Gregersen, Ida; Dahl, Tuva Børresdatter; Suganthan, Rajikala; Segers, Filip; Østlie, Ingunn; Otten, Jeroen J.T.; Gomez, Luisa Fernanda Luna; Ketelhuth, Daniel F.J.; Lundberg, Anna M.; Neurauter, Christine Gran; Hildrestrand, Gunn Annette; Skjelland, Mona; Bjørndal, Bodil; Svardal, Asbjørn M.; Iversen, Per Ole; Hedin, Ulf; Nygård, Ståle; Olstad, Ole Kristoffer; Krohg-Sørensen, Kirsten; Slupphaug, Geir; Eide, Lars; Kusnierczyk, Anna; Folkersen, Lasse; Ueland, Thor; Berge, Rolf Kristian; Hansson, Göran K.; Biessen, Erik A.L.; Halvorsen, Bente; Bjørås, Magnar & Aukrust, Pål (2016). Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice. Scientific Reports.  ISSN 2045-2322.  6:28337 . doi: 10.1038/srep28337 Fulltekst i vitenarkiv.
• Skjellegrind, Håvard Kjesbu; Fayzullin, Artem; Johnsen, Erik Otter; Eide, Lars; Langmoen, Iver Arne; Moe, Morten Carsten & Vik-Mo, Einar O. (2016). Short-Term Differentiation of Glioblastoma Stem Cells Induces Hypoxia Tolerance. Neurochemical Research.  ISSN 0364-3190.  41(7), s 1545- 1558 . doi: 10.1007/s11064-016-1868-2
• Bjørge, Monica Dahl; Hildrestrand, Gunn Annette; Scheffler, Katja; Suganthan, Rajikala; Rolseth, Veslemøy; Kusnierczyk, Anna; Rowe, Alexander D.; Vågbø, Cathrine Broberg; Vetlesen, Susanne; Eide, Lars; Slupphaug, Geir; Yusaku, Nakabeppu; Timothy, Bredy; Klungland, Arne & Bjørås, Magnar (2015). Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice. Cell reports.  ISSN 2211-1247.  13(12), s 2671- 2678 . doi: 10.1016/j.celrep.2015.12.001 Fulltekst i vitenarkiv. Vis sammendrag

  Ogg1 and Mutyh DNA glycosylases cooperate to prevent mutations caused by 8-oxoG, a major premutagenic DNA lesion associated with cognitive decline. We have examined behavior and cognitive function in mice deficient of these glycosylases. Ogg1−/−Mutyh−/− mice were more active and less anxious, with impaired learning ability. In contrast, Mutyh−/− mice showed moderately improved memory. We observed no apparent change in genomic 8-oxoG levels, suggesting that Ogg1 and Mutyh play minor roles in global repair in adult brain. Notably, transcriptome analysis of hippocampus revealed that differentially expressed genes in the mutants belong to pathways known to be involved in anxiety and cognition. Esr1 targets were upregulated, suggesting a role of Ogg1 and Mutyh in repression of Esr1 signaling. Thus, beyond their involvement in DNA repair, Ogg1 and Mutyh regulate hippocampal gene expression related to cognition and behavior, suggesting a role for the glycosylases in regulating adaptive behavior.

• Bliksøen, Marte; Baysa, Anton; Eide, Lars; Bjørås, Magnar; Suganthan, Rajikala; Vaage, Ingvar Jarle; Stensløkken, Kåre-Olav & Valen, Guro (2015). Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart. Journal of Molecular and Cellular Cardiology.  ISSN 0022-2828.  78, s 9- 22 . doi: 10.1016/j.yjmcc.2014.11.010
• Lauritzen, Knut Husø; Kleppa, Liv; Aronsen, Jan Magnus; Eide, Lars; Carlsen, Harald; Haugen, Øyvind Pernell; Sjaastad, Ivar; Klungland, Arne; Rasmussen, Lene Juel; Attramadal, Håvard; Storm-Mathisen, Jon & Bergersen, Linda Hildegard (2015). Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure. American Journal of Physiology. Heart and Circulatory Physiology.  ISSN 0363-6135.  309(3), s H434- H449 . doi: 10.1152/ajpheart.00253.2014
• Yang, Mingyi; Lin, Xiaolin; Rowe, Alexander D.; Rognes, Torbjørn; Eide, Lars & Bjørås, Magnar (2015). Transcriptome analysis of human OXR1 depleted cells reveals its role in regulating the p53 signaling pathway. Scientific Reports.  ISSN 2045-2322.  5 . doi: 10.1038/srep17409 Fulltekst i vitenarkiv.
• Hereng, Tuva Holt; Elgstøen, Katja B. Prestø; Eide, Lars; Rosendal, Ken Roger & Skålhegg, Bjørn Steen (2014). Serum albumin and HCO<sub>3</sub><sup>-</sup> regulate separate pools of ATP in human spermatozoa. Human Reproduction.  ISSN 0268-1161.  29(5), s 918- 930 . doi: 10.1093/humrep/deu028
• Hystad, Eva Marit; Amdam, Gro Vang & Eide, Lars (2014). Mitochondrial DNA integrity changes with age but does not correlate with learning performance in honey bees. Experimental Gerontology.  ISSN 0531-5565.  49, s 12- 18 . doi: 10.1016/j.exger.2013.10.013
• Jalland, Clara; Benestad, Sylvie Lafond; Ersdal, Cecilie; Scheffler, Katja; Suganthan, Rajikala; Nakabeppu, Yusaku; Eide, Lars; Bjørås, Magnar & Tranulis, Michael A. (2014). Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage. Free Radical Biology & Medicine.  ISSN 0891-5849.  68, s 1- 7 . doi: 10.1016/j.freeradbiomed.2013.11.013
• Strand, Janne Maren; Scheffler, Katja; Bjørås, Magnar & Eide, Lars (2014). The distribution of DNA damage is defined by region-specific susceptibility to DNA damage formation rather than repair differences. DNA Repair.  ISSN 1568-7864.  18(1), s 44- 51 . doi: 10.1016/j.dnarep.2014.03.003
• Strand, Janne Maren; Skinnes, Ragnhild; Scheffler, Katja; Rootwelt, Terje; Woldseth, Berit; Bjørås, Magnar & Eide, Lars (2014). Genome instability in Maple Syrup Urine Disease correlates with impaired mitochondrial biogenesis. Metabolism: Clinical and Experimental.  ISSN 0026-0495.  63(8), s 1063- 1070 . doi: 10.1016/j.metabol.2014.05.003
• Wang, Wei; Scheffler, Katja; Esbensen, Qin Ying; Strand, Janne Maren; Stewart, James B.; Bjørås, Magnar & Eide, Lars (2014). Addressing RNA integrity to determine the impact of mitochondrial DNA mutations on brain mitochondrial function with age. PLOS ONE.  ISSN 1932-6203.  9(5) . doi: 10.1371/journal.pone.0096940
• Yang, Mingyi; Luna, Linda; Sørbø, Jan Gunnar; Alseth, Ingrun; Johansen, Rune Forstrøm; Backe, Paul Hoff; Danbolt, Niels Christian; Eide, Lars & Bjørås, Magnar (2014). Human OXR1 maintains mitochondrial DNA integrity and counteracts hydrogen peroxide-induced oxidative stress by regulating antioxidant pathways involving p21. Free Radical Biology & Medicine.  ISSN 0891-5849.  77, s 41- 48 . doi: 10.1016/j.freeradbiomed.2014.09.003
• Yuzefovych, Larysa V.; Schuler, A. Michele; Chen, Jemimah; Alvarez, Diego F.; Eide, Lars; Ledoux, Susan P.; Wilson, Glenn L. & Rachek, Lyudmila I. (2013). Alteration of Mitochondrial Function and Insulin Sensitivity in Primary Mouse Skeletal Muscle Cells Isolated From Transgenic and Knockout Mice: Role of OGG1. Endocrinology.  ISSN 0013-7227.  154(8), s 2640- 2649 . doi: 10.1210/en.2013-1076
• Halsne, Ruth; Esbensen, Qin Ying; Wang, Wei; Scheffler, Katja; Suganthan, Rajikala; Bjørås, Magnar & Eide, Lars (2012). Lack of the DNA glycosylases MYH and OGG1 in the cancer prone double mutant mouse does not increase mitochondrial DNA mutagenesis. DNA Repair.  ISSN 1568-7864.  11(3), s 278- 285 . doi: 10.1016/j.dnarep.2011.12.001
• Hereng, Tuva Holt; Elgstøen, Katja B. Prestø; Cederkvist, Fritjof Henning; Eide, Lars; Jahnsen, Tore; Skålhegg, Bjørn Steen & Rosendal, K.R (2011). Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa. Human Reproduction.  ISSN 0268-1161.  26(12), s 3249- 3263 . doi: 10.1093/humrep/der317
• Kaarbø, Mari; Ager-Wick, Eirill; Osenbroch, Pia Madeleine Øistad; Kilander, Anette; Skinnes, Ragnhild; Müller, Fredrik & Eide, Lars (2011). Human cytomegalovirus infection increases mitochondrial biogenesis. Mitochondrion (Amsterdam. Print).  ISSN 1567-7249.  11(6), s 935- 945 . doi: 10.1016/j.mito.2011.08.008
• Wang, Wei; Esbensen, Ying; Kunke, David; Suganthan, Rajikala; Rachek, Lyudmila; Bjørås, Magnar & Eide, Lars (2011). Mitochondrial DNA Damage Level Determines Neural Stem Cell Differentiation Fate. Journal of Neuroscience.  ISSN 0270-6474.  31(26), s 9746- 9751 . doi: 10.1523/JNEUROSCI.0852-11.2011
• Brodtkorb, Else; Strand, Janne Maren; Backe, Paul Hoff; Lund, Anne Marie; Bjørås, Magnar; Rootwelt, Terje; Rootwelt, Helge; Woldseth, Berit & Eide, Lars (2010). Four novel mutations identified in Norwegian patients result in intermittent maple syrup urine disease when combined with the R301C mutation. Molecular Genetics and Metabolism.  ISSN 1096-7192.  100(4), s 324- 332 . doi: 10.1016/j.ymgme.2010.04.017
• Lauritzen, Knut Husø; Moldestad, Olve; Eide, Lars; Carlsen, Harald; Nesse, Gaute; Storm, Johan Frederik; Mansuy, Isabelle M.; Bergersen, Linda Hildegard & Klungland, Arne (2010). Mitochondrial DNA Toxicity in Forebrain Neurons Causes Apoptosis, Neurodegeneration, and Impaired Behavior. Molecular and Cellular Biology.  ISSN 0270-7306.  30(6), s 1357- 1367 . doi: 10.1128/MCB.01149-09 Vis sammendrag

  Mitochondrial dysfunction underlying changes in neurodegenerative diseases is often associated with apoptosis and a progressive loss of neurons, and damage to the mitochondrial genome is proposed to be involved in such pathologies. In the present study we designed a mouse model that allows us to specifically induce mitochondrial DNA toxicity in the forebrain neurons of adult mice. This is achieved by CaMKII-regulated inducible expression of a mutated version of the mitochondrial UNG DNA repair enzyme (mutUNG1). This enzyme is capable of removing thymine from the mitochondrial genome. We demonstrate that a continual generation of apyrimidinic sites causes apoptosis and neuronal death. These defects are associated with behavioral alterations characterized by increased locomotor activity, impaired cognitive abilities, and lack of anxietylike responses. In summary, whereas mitochondrial base substitution and deletions previously have been shown to correlate with premature and natural aging, respectively, we show that a high level of apyrimidinic sites lead to mitochondrial DNA cytotoxicity, which causes apoptosis, followed by neurodegeneration.

• Wang, Wei; Osenbroch, Pia Madeleine Øistad; Skinnes, Ragnhild; Esbensen, Qin Ying; Bjørås, Magnar & Eide, Lars (2010). Mitochondrial DNA Integrity Is Essential for Mitochondrial Maturation During Differentiation of Neural Stem Cells. Stem Cells.  ISSN 1066-5099.  28(12), s 2195- 2204 . doi: 10.1002/stem.542
• Osenbroch, Pia Madeleine Øistad; Auk, Pia Nenseth; Halsne, Ruth; Strand, Janne Maren; Johansen, Rune Forstrøm; van der Pluijm, I & Eide, Lars (2009). Accumulation of mitochondrial DNA damage and bioenergetic dysfunction in CSB defective cells. The FEBS Journal.  ISSN 1742-464X.  276(10), s 2811- 2821 . doi: 10.1111/j.1742-4658.2009.07004.x
• Sejersted, Yngve; Aasland, Anne Leikny; Bjørås, Magnar; Eide, Lars & Saugstad, Ola Didrik (2009). Accumulation of 8-Oxoguanine in Liver DNA During Hyperoxic Resuscitation of Newborn Mice. Pediatric Research.  ISSN 0031-3998.  66(5), s 533- 538 . doi: 10.1203/PDR.0b013e3181ba1a42
• Yndestad, Arne; Neurauter, Christine Gran; Øie, Erik; Johansen, Rune Forstrøm; Vinge, Leif Erik; Eide, Lars; Luna, Gomez Luisa; Aukrust, Pål & Bjørås, Magnar (2009). Up-regulation of myocardial DNA base excision repair activities in experimental heart failure. Mutation research.  ISSN 0027-5107.  666(1-2), s 32- 38 . doi: 10.1016/j.mrfmmm.2009.03.008
• Ringvoll, Jeanette; Uldal, Lene; Røed, Marie Aslaksen; Stenersen, Karen Oppland; Baynton, K; Klungland, Arne & Eide, Lars (2007). Mutations in the RAD27 and SGS1 genes differentially affect the chronological and replicative lifespan of yeast cells growing on glucose and glycerol. FEMS Yeast Research.  ISSN 1567-1356.  7, s 848- 859 . doi: 10.1111/j.1567-1364.2007.00248.x
• Eide, Lars & McMurray, Cynthia T. (2005). Culture of adult mouse neurons. BioTechniques.  ISSN 0736-6205.  38(1), s 99- 104
• Trushina, E; Dyer, RB; Badger, JD; Ure, D; Eide, Lars; Tran, DD; Vrieze, BT; Legendre-Guillemin, V; McPherson, PS; Mandavilli, BS; Van Houten, B; Zeitlin, S; McNiven, M; Aebersold, R; Hayden, M; Parisi, JE; Seeberg, Erling Christen; Dragatsis, I; Doyle, K; Bender, A; Chacko, C & McMurray, CT (2004). Muntant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro. Molecular and Cellular Biology.  ISSN 0270-7306.  24, s 8195- 8209
• Ulbert, S; Eide, Lars; Seeberg, Erling Christen & Borst, P. (2004). Base J, found in nuclear DNA of Trypanosoma brucei, is not a target for DNA glycosylases. DNA Repair.  ISSN 1568-7864.  3(2), s 145- 154

Se alle arbeider i Cristin

• Bousquet, Paula; Meltzer, Sebastian; Sønstevold, Linda; Esbensen, Qin Ying; Dueland, Svein; Flatmark, Kjersti; Sitter, Beathe; Bathen, Tone Frost; Seierstad, Therese; Redalen, Kathrine; Eide, Lars & Ree, Anne Hansen (2019). Markers of mitochondrial metabolism in tumor hypoxia, systemic inflammation, and adverse outcome of rectal cancer. Translational Oncology.  ISSN 1944-7124.  12(1), s 76- 83 . doi: 10.1016/j.tranon.2018.09.010
• Bousquet, Paula; Meltzer, Sebastian; Sønstevold, Linda; Esbensen, Qin Ying; Lyckander, Lars Gustav; Dueland, Svein; Flatmark, Kjersti; Redalen, Kathrine Røe; Eide, Lars & Ree, Anne Hansen (2017). Reactive oxygen species (ROS) and mitochondrial DNA (mtDNA) damage in tumor hypoxia, poor radiotherapy response, and metastatic progression of rectal cancer. Cancer Research.  ISSN 0008-5472.  77, s 1782- 1782 . doi: 10.1158/1538-7445.AM2017-1782
• Li, Xiaoran; Zhong, Yali; Lu, Jie; Axcrona, Karol; Eide, Lars; Syljuåsen, Randi G.; Qian, Peng; Wang, Junbai; Zhang, Hongquan; Goscinski, Mariusz Adam; Kvalheim, Gunnar; Nesland, Jahn M & Suo, Zhenhe (2017). Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features.. OncoTarget.  ISSN 1949-2553.  8(4), s 7208- 7213 . doi: 10.18632/oncotarget.14800
• Eide, Lars (2016). Hvordan kvaliteten på mitokondrielt DNA påvirker brystkreft. BestPractice onkologi hematologi i Norge.  (27), s 28- 29
• Wang, Wei; Scheffler, Katja; Esbensen, Qin Ying & Eide, Lars (2016). Quantification of DNA Damage by Real-Time qPCR, In John M Walker (ed.),  Mitochondrial DNA Methods and Protocols.  Springer.  ISBN 978-1-4939-3039-5.  3.  s 27 - 32
• Yuzefovych, Larysa V.; Kahn, Andrea G.; Schuler, Michele A.; Eide, Lars; Arora, Ritu; Wilson, Glenn L.; Tan, Ming & Rachek, Lyudmila I. (2016). Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis. Cancer Research.  ISSN 0008-5472.  76(1), s 30- 34 . doi: 10.1158/0008-5472.CAN-15-0692
• Jackson, Catherine; Eidet, Jon Roger; Reppe, Sjur; Eide, Lars; Tønseth, Kim Aleksander; Bergersen, Linda Hildegard; Dartt, Darlene A.; Griffith, May & Utheim, Tor Paaske (2015). Storage of cultured skin cell sheets for treatment of limbal stem cell deficiency.
• Jackson, Catherine; Eidet, Jon Roger; Tønseth, Kim Aleksander; Eide, Lars; Messelt, Edward B. & Utheim, Tor Paaske (2015). 12oC is the Optimal Storage Temperature for Retention of Viability and Undifferentiated Cell Character of Cultured Epidermal Cells.
• Wang, Wei; Esbensen, Qin Ying; Scheffler, Katja & Eide, Lars (2015). Analysis of Mitochondrial DNA and RNA Integrity by a Real-Time qPCR-Based Method, In John M Walker (ed.),  Mitochondrial Medicine.  Springer.  ISBN 978-1-4939-2256-7.  10.  s 97 - 106
• Distante, Sonia; Høie, Kari; Mørkrid, Lars & Eide, Lars (2013). ASSESSING THE MITOCHONDRIAL IRON METABOLISM IN HEREDITARY HEMOCHROMATOSIS. American Journal of Hematology.  ISSN 0361-8609.  88(5), s E207- E207
• Halsne, Ruth & Eide, Lars (2011). Mitochondrial and cellular effects of mitochondrial DNA damage.
• Osenbroch, Pia Madeleine Øistad & Eide, Lars (2011). Characterization of mitochondrial function in Cockayne syndrome, human cytomegalovirus infection and neural stem cell differentiation. Series of dissertations submitted to the Faculty of Medicine, University of Oslo. 1069.
• Bugge, Markus; Eide, Lars; Grünfeld, Leo A. & Thune, Taran Mari (2010). Brukerstyrte innovasjonsprosjekter og samfunnsøkonomisk avkastning.

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