Ludvig Magne Sollid

• Li, Jing; Zaslavsky, Maxim; Su, Yapeng; Guo, Jing; Sikora, Michael J. & van Unen, Vincent [Vis alle 36 forfattere av denne artikkelen] (2022). KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19. Science. ISSN 0036-8075. 376:eabi9591(6590), s. 1–15. doi: 10.1126/science.abi9591.
• Sollid, Ludvig Magne (2022). Epstein-Barr virus as a driver of multiple sclerosis. Science immunology. ISSN 2470-9468. 7(70). doi: 10.1126/sciimmunol.abo7799.
• Lindeman, Ida; Polak, Justyna; Qiao, Shuo-Wang; Holmøy, Trygve; Høglund, Rune Alexander & Vartdal, Frode [Vis alle 9 forfattere av denne artikkelen] (2022). Stereotyped B-cell responses are linked to IgG constant region polymorphisms in multiple sclerosis. European Journal of Immunology. ISSN 0014-2980. 52(4), s. 550–565. doi: 10.1002/eji.202149576.
• Ciacchi, Laura; Farenc, Carine; Dahal-Koirala, Shiva; Petersen, Jan; Sollid, Ludvig Magne & Reid, Hugh H. [Vis alle 7 forfattere av denne artikkelen] (2022). Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease. Journal of Biological Chemistry. ISSN 0021-9258. 298(3). doi: 10.1016/j.jbc.2022.101619.
• Christophersen, Asbjørn Otto; Dahal-Koirala, Shiva; Chlubnova, Marketa; Jahnsen, Jørgen; Lundin, Knut & Sollid, Ludvig Magne (2022). Phenotype-Based Isolation of Antigen-Specific CD4⁺ T Cells in Autoimmunity: A Study of Celiac Disease. Advanced Science. ISSN 2198-3844. 9(10). doi: 10.1002/advs.202104766.
• Lindstad, Christian Borgen; du Pré, Marie Fleur; Stamnaes, Jorunn & Sollid, Ludvig Magne (2022). Injection of prototypic celiac anti-transglutaminase 2 antibodies in mice does not cause enteropathy. PLOS ONE. ISSN 1932-6203. 17(4). doi: 10.1371/journal.pone.0266543.
• Dahal-Koirala, Shiva; Balaban, Gabriel; Neumann, Ralf Stefan; Scheffer, Lonneke; Lundin, Knut & Greiff, Victor [Vis alle 9 forfattere av denne artikkelen] (2022). TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences. Briefings in Bioinformatics. ISSN 1467-5463. doi: 10.1093/bib/bbab566.
• Mikocziova, Ivana; Peres, Ayelet; Gidoni, Moriah; Greiff, Victor; Yaari, Gur & Sollid, Ludvig Magne (2021). Germline polymorphisms and alternative splicing of human immunoglobulin light chain genes. iScience. ISSN 2589-0042. 24:103192(10), s. 1–19. doi: 10.1016/j.isci.2021.103192. Fulltekst i vitenarkiv
• Mikocziova, Ivana; Greiff, Victor & Sollid, Ludvig Magne (2021). Immunoglobulin germline gene variation and its impact on human disease. Genes and Immunity. ISSN 1466-4879. 22(4), s. 205–217. doi: 10.1038/s41435-021-00145-5. Fulltekst i vitenarkiv
• Sollid, Ludvig Magne (2021). Gut tissue-resident memory T cells in coeliac disease. Scandinavian Journal of Immunology. ISSN 0300-9475. 95:e13120(1), s. 1–10. doi: 10.1111/sji.13120. Fulltekst i vitenarkiv
• Slabodkin, Andrei; Chernigovskaia, Maria; Mikocziova, Ivana; Akbar, Rahmad; Scheffer, Lonneke & Pavlović, Milena [Vis alle 16 forfattere av denne artikkelen] (2021). Individualized VDJ recombination predisposes the available Ig sequence space. Genome Research. ISSN 1088-9051. s. 2209–2224. doi: 10.1101/gr.275373.121. Fulltekst i vitenarkiv
• Pavlović, Milena; Scheffer, Lonneke; Motwani, Keshav; Kanduri, Chakravarthi; Kompova, Radmila & Vazov, Nikolay Aleksandrov [Vis alle 41 forfattere av denne artikkelen] (2021). The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires. Nature Machine Intelligence. 3(11), s. 936–944. doi: 10.1038/s42256-021-00413-z.
• Lindstad, Christian Borgen; Dewan, Alisa Elinsdatter; Stamnæs, Jorunn; Sollid, Ludvig Magne & du Pré, Marie Fleur (2021). TG2-gluten complexes as antigens for gluten-specific and transglutaminase-2 specific B cells in celiac disease. PLOS ONE. ISSN 1932-6203. 16:e0259082(11), s. 1–14. doi: 10.1371/journal.pone.0259082. Fulltekst i vitenarkiv
• Lindeman, Ida & Sollid, Ludvig Magne (2021). Single-cell approaches to dissect adaptive immune responses involved in autoimmunity: the case of celiac disease. Mucosal Immunology. ISSN 1933-0219. 15, s. 51–63. doi: 10.1038/s41385-021-00452-0. Fulltekst i vitenarkiv
• Christophersen, Asbjørn Otto; Zühlke, Stephanie; Lund, Eivind Gard; Snir, Omri; Dahal-Koirala, Shiva & Risnes, Louise Fremgaard [Vis alle 9 forfattere av denne artikkelen] (2021). Pathogenic T cells in celiac disease change phenotype on gluten challenge: Implications for T-cell-directed therapies. Advanced Science. ISSN 2198-3844. 8(21), s. 1–11. doi: 10.1002/advs.202102778.
• Frick, Rahel; Høydahl, Lene Støkken; Petersen, Jan; du Pré, Fleur; Kumari, Shraddha & Berntsen, Grete [Vis alle 20 forfattere av denne artikkelen] (2021). A high-affinity human TCR-like antibody detects celiac disease gluten peptide-MHC complexes and inhibits T cell activation. Science immunology. ISSN 2470-9468. 6:eabg4925(62), s. 1–16. doi: 10.1126/sciimmunol.abg4925. Fulltekst i vitenarkiv
• Dewan, Alisa Elinsdatter; Koentgen, Frank; Johansen, Marie Kongshaug; du Pré, Fleur & Sollid, Ludvig Magne (2021). Generation of an HLA-DQ2.5 knock-in mouse. ImmunoHorizons. ISSN 2573-7732. 5(1), s. 25–32. doi: 10.4049/immunohorizons.2000107. Fulltekst i vitenarkiv
• Bakker, Olivier B.; Ramírez-Sánchez, Aarón D.; Borek, Zuzanna A.; de Klein, Niek; Li, Yang & Modderman, Rutger [Vis alle 19 forfattere av denne artikkelen] (2021). Potential impact of celiac disease genetic risk factors on T cell receptor signaling in gluten-specific CD4+ T cells. Scientific Reports. ISSN 2045-2322. 11:9252(1), s. 1–15. doi: 10.1038/s41598-021-86612-5. Fulltekst i vitenarkiv
• Risnes, Louise Fremgaard; Eggesbø, Linn Margrethe; Zühlke, Stephanie; Dahal-Koirala, Shiva; Neumann, Ralf Stefan & Lundin, Knut Erik Aslaksen [Vis alle 8 forfattere av denne artikkelen] (2021). Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease. Mucosal Immunology. ISSN 1933-0219. 14(4), s. 842–851. doi: 10.1038/s41385-021-00385-8. Fulltekst i vitenarkiv
• Dahal-Koirala, Shiva; Risnes, Louise Fremgaard; Neumann, Ralf Stefan; Christophersen, Asbjørn; Lundin, Knut E. A. & Sandve, Geir Kjetil [Vis alle 8 forfattere av denne artikkelen] (2021). Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs. Frontiers in Immunology. ISSN 1664-3224. 12:639672, s. 1–13. doi: 10.3389/fimmu.2021.639672. Fulltekst i vitenarkiv
• Shemesh, Or; Polak, Pazit; Lundin, Knut Erik Aslaksen; Sollid, Ludvig M. & Yaari, Gur (2021). Machine Learning Analysis of Naïve B-Cell Receptor Repertoires Stratifies Celiac Disease Patients and Controls. Frontiers in Immunology. ISSN 1664-3224. 12:627813, s. 1–11. doi: 10.3389/fimmu.2021.627813. Fulltekst i vitenarkiv
• Qiao, Shuo-Wang; Dahal-Koirala, Shiva; Eggesbø, Linn Margrethe; Lundin, Knut E. A. & Sollid, Ludvig Magne (2021). Frequency of Gluten-Reactive T Cells in Active Celiac Lesions Estimated by Direct Cell Cloning. Frontiers in Immunology. ISSN 1664-3224. 12:646163, s. 1–8. doi: 10.3389/fimmu.2021.646163. Fulltekst i vitenarkiv
• van der Graaf, Adriaan; Zorro, Maria; Claringbould, Annique; Võsa, Urmo; Aguirre-Gamboa, Raul & Li, Chan [Vis alle 24 forfattere av denne artikkelen] (2021). Systematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease. Frontiers in Genetics. ISSN 1664-8021. 11:562434, s. 1–16. doi: 10.3389/fgene.2020.562434. Fulltekst i vitenarkiv
• Lindeman, Ida; Zhou, Chunyan; Eggesbø, Linn Margrethe; Miao, Zhichao; Polak, Justyna & Lundin, Knut Erik Aslaksen [Vis alle 10 forfattere av denne artikkelen] (2021). Longevity, clonal relationship, and transcriptional program of celiac disease-specific plasma cells. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 218:e20200852(2), s. 1–16. doi: 10.1084/jem.20200852. Fulltekst i vitenarkiv
• Stamnæs, Jorunn; Stray, Daniel; Stensland, Maria; Sarna, Vikas Kumar; Nyman, Tuula Anneli & Lundin, Knut Erik Aslaksen [Vis alle 7 forfattere av denne artikkelen] (2021). In well‐treated celiac patients low‐level mucosal inflammation predicts response to 14‐day gluten challenge. Advanced Science. ISSN 2198-3844. 8:2003526(4), s. 1–7. doi: 10.1002/advs.202003526. Fulltekst i vitenarkiv
• Wyrozemski, Lukasz Adam; Sollid, Ludvig Magne & Qiao, Shuo Wang (2020). C-type lectin-like CD161 is not a co-signalling receptor in gluten-reactive CD4 + T cells. Scandinavian Journal of Immunology. ISSN 0300-9475. 00:e13016, s. 1–9. doi: 10.1111/sji.13016. Fulltekst i vitenarkiv
• Mikocziova, Ivana; Gidoni, Moriah; Lindeman, Ida; Peres, Ayelet; Snir, Omri & Yaari, Gur [Vis alle 7 forfattere av denne artikkelen] (2020). Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions. Nucleic Acids Research (NAR). ISSN 0305-1048. 48(10), s. 5499–5510. doi: 10.1093/NAR/GKAA310. Fulltekst i vitenarkiv
• Iversen, Rasmus & Sollid, Ludvig Magne (2020). Autoimmunity provoked by foreign antigens: In celiac disease, exogenous gluten drives T cell-B cell interactions that cause autoimmunity. Science. ISSN 0036-8075. 368(6487), s. 132–133. doi: 10.1126/science.aay3037. Fulltekst i vitenarkiv
• Ting, Yi Tian; Dahal-Koirala, Shiva; Kim, Hui Shi Keshia; Qiao, Shuo Wang; Neumann, Ralf Stefan & Lundin, Knut Erik Aslaksen [Vis alle 10 forfattere av denne artikkelen] (2020). A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 117(6), s. 3063–3073. doi: 10.1073/pnas.1914308117. Fulltekst i vitenarkiv
• du Pré, Fleur; Blazevski, Jana; Dewan, Alisa Elinsdatter; Stamnæs, Jorunn; Kanduri, Srinivasa Kalyana Chakravarthi & Sandve, Geir Kjetil [Vis alle 13 forfattere av denne artikkelen] (2020). B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 217:e20190860.(2), s. 1–14. doi: 10.1084/jem.20190860. Fulltekst i vitenarkiv
• Sollid, Ludvig Magne; Tye-Din, Jason A.; Qiao, Shuo Wang; Anderson, Robert; Gianfrani, Carmen & Koning, Frits (2019). Update 2020: nomenclature and listing of celiac disease - relevant gluten epitopes recognized by CD4+ T cells. Immunogenetics. ISSN 0093-7711. 72(1-2), s. 85–88. doi: 10.1007/s00251-019-01141-w. Fulltekst i vitenarkiv
• Goel, Gautam; Tye-Din, Jason A.; Qiao, Shuo Wang; Russell, Amy K.; Mayassi, Toufic & Ciszewski, Cezary [Vis alle 16 forfattere av denne artikkelen] (2019). Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease. Indian Journal of Pure & Applied Physics. ISSN 0019-5596. 5:eaaw7756(8), s. 1–15. doi: 10.1126/sciadv.aaw7756. Fulltekst i vitenarkiv
• Tye-Din, Jason A.; Skodje, Gry Irene; Sarna, Vikas Kumar; Dzuris, John L.; Russell, Amy K. & Goel, Gautam [Vis alle 12 forfattere av denne artikkelen] (2019). Cytokine release after gluten ingestion differentiates coeliac disease from self-reported gluten sensitivity. United European Gastroenterology journal. ISSN 2050-6406. s. 1–11. doi: 10.1177/2050640619874173. Fulltekst i vitenarkiv
• Dahal-Koirala, Shiva; Neumann, Ralf Stefan; Jahnsen, Jørgen; Lundin, Knut Erik Aslaksen & Sollid, Ludvig Magne (2019). On the immune response to barley in celiac disease: Biased and public T-cell receptor usage to a barley unique and immunodominant gluten epitope. European Journal of Immunology. ISSN 0014-2980. s. 1–14. doi: 10.1002/eji.201948253. Fulltekst i vitenarkiv
• Eggesbø, Linn Margrethe; Risnes, Louise Fremgaard; Neumann, Ralf Stefan; Lundin, Knut Erik Aslaksen; Christophersen, Asbjørn & Sollid, Ludvig Magne (2019). Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease. Mucosal Immunology. ISSN 1933-0219. s. 1–9. doi: 10.1038/s41385-019-0222-9. Fulltekst i vitenarkiv
• Zühlke, Stephanie; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva; Christophersen, Asbjørn; Sollid, Ludvig Magne & Lundin, Knut Erik Aslaksen (2019). CD38 expression on gluten-specific T cells is a robust marker of gluten re-exposure in coeliac disease . United European Gastroenterology journal. ISSN 2050-6406. 7(10), s. 1337–1344. doi: 10.1177/2050640619874183.
• Qiao, Shuo Wang & Sollid, Ludvig Magne (2019). Two novel HLA-DQ2.5-restricted gluten T cell epitopes in the DQ2.5-glia-γ4 epitope family. Immunogenetics. ISSN 0093-7711. doi: 10.1007/s00251-019-01138-5.
• Bartolomé Casado, Raquel; Landsverk, Ole J. B.; Chauhan, Sudhir Kumar; Richter, Lisa Maria; Phung, Danh & Greiff, Victor [Vis alle 18 forfattere av denne artikkelen] (2019). Resident memory CD8 T cells persist for years in human small intestine. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 216(10), s. 2412–2426. doi: 10.1084/jem.20190414. Fulltekst i vitenarkiv
• Frick, Rahel; Gunnarsen, Kristin Støen; Dahal-Koirala, Shiva; Risnes, Louise Fremgaard; Sollid, Ludvig Magne & Sandlie, Inger [Vis alle 8 forfattere av denne artikkelen] (2019). A TRAV26-1-encoded recognition motif focuses the biased T cell response in celiac disease. European Journal of Immunology. ISSN 0014-2980. 50, s. 142–145. doi: 10.1002/eji.201948235. Fulltekst i vitenarkiv
• Snir, Omri; Kanduri, Srinivasa Kalyana Chakravarthi; Lundin, Knut Erik Aslaksen; Sandve, Geir Kjetil & Sollid, Ludvig Magne (2019). Transcriptional profiling of human intestinal plasma cells reveals effector functions beyond antibody production. United European Gastroenterology journal. ISSN 2050-6406. 0(0), s. 1–9. doi: 10.1177/2050640619862461.
• Iversen, Rasmus; Roy, Bishnudeo; Stamnæs, Jorunn; Høydahl, Lene Støkken; Hnida, Kathrin & Neumann, Ralf Stefan [Vis alle 9 forfattere av denne artikkelen] (2019). Efficient T cell–B cell collaboration guides autoantibody epitope bias and onset of celiac disease. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 116(30), s. 15134–15139. doi: 10.1073/pnas.1901561116. Fulltekst i vitenarkiv
• Hung, Shu-Chen; Hou, Tieying; Jiang, Wei; Wang, Nan; Qiao, Shuo Wang & Chow, I-Ting [Vis alle 12 forfattere av denne artikkelen] (2019). Epitope selection for HLA-DQ2 presentation: Implications for celiac disease and viral defense. Journal of Immunology. ISSN 0022-1767. 202(9), s. 2558–2569. doi: 10.4049/jimmunol.1801454.
• Gidoni, Moriah; Snir, Omri; Peres, Ayelet; Polak, Pazit; Lindeman, Ida & Mikocziova, Ivana [Vis alle 13 forfattere av denne artikkelen] (2019). Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotyping. Nature Communications. ISSN 2041-1723. 10:628, s. 1–14. doi: 10.1038/s41467-019-08489-3. Fulltekst i vitenarkiv
• Christophersen, Asbjørn; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva & Sollid, Ludvig Magne (2019). Therapeutic and diagnostic implications of T cell scarring in celiac disease and beyond. Trends in Molecular Medicine. ISSN 1471-4914. 25(10), s. 836–852. doi: 10.1016/j.molmed.2019.05.009. Fulltekst i vitenarkiv
• Christophersen, Asbjørn; Lund, Eivind Gard; Snir, Omri; Solà, Elsa; Kanduri, Srinivasa Kalyana Chakravarthi & Dahal-Koirala, Shiva [Vis alle 15 forfattere av denne artikkelen] (2019). Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions. Nature Medicine. ISSN 1078-8956. 25(5), s. 734–737. doi: 10.1038/s41591-019-0403-9. Fulltekst i vitenarkiv
• Høydahl, Lene Støkken; Richter, Lisa Maria; Frick, Rahel; Snir, Omri; Gunnarsen, Kristin Støen & Landsverk, Ole J. B. [Vis alle 18 forfattere av denne artikkelen] (2019). Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease. Gastroenterology. ISSN 0016-5085. 156(5), s. 1428–1439.e10. doi: 10.1053/j.gastro.2018.12.013. Fulltekst i vitenarkiv
• Dahal-Koirala, Shiva; Ciacchi, Laura; Petersen, Jan; Risnes, Louise Fremgaard; Neumann, Ralf Stefan & Christophersen, Asbjørn [Vis alle 11 forfattere av denne artikkelen] (2018). Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes . Journal of Biological Chemistry. ISSN 0021-9258. 294(3), s. 941–952. doi: 10.1074/jbc.RA118.005736. Fulltekst i vitenarkiv
• Risnes, Louise Fremgaard; Christophersen, Asbjørn; Dahal-Koirala, Shiva; Neumann, Ralf Stefan; Sandve, Geir Kjetil & Sarna, Vikas Kumar [Vis alle 9 forfattere av denne artikkelen] (2018). Disease-driving CD4+ T cell clonotypes persist for decades in celiac disease. Journal of Clinical Investigation. ISSN 0021-9738. 128(6), s. 2642–2650. doi: 10.1172/JCI98819. Fulltekst i vitenarkiv
• Shao, Wenguang; Pedrioli, Patrick G.A.; Wolski, Witold; Scurtescu, Cristian; Schmid, Emanuel & Vizcaíno, Juan Antonio [Vis alle 46 forfattere av denne artikkelen] (2018). The SysteMHC Atlas project. Nucleic Acids Research (NAR). ISSN 0305-1048. 46(1), s. D1237–D1247. doi: 10.1093/nar/gkx664. Fulltekst i vitenarkiv
• Tutturen, Astrid Elisabeth Voorham; Dørum, Siri; Clancy, Trevor; Reims, Henrik Mikael; Christophersen, Asbjørn & Lundin, Knut Erik Aslaksen [Vis alle 9 forfattere av denne artikkelen] (2018). Characterization of the Small Intestinal Lesion in Celiac Disease by Label-Free Quantitative Mass Spectrometry. American Journal of Pathology. ISSN 0002-9440. 188(7), s. 1563–1579. doi: 10.1016/j.ajpath.2018.03.017. Fulltekst i vitenarkiv
• Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Neumann, Ralf Stefan; Bjerregaard-Andersen, Kaare; Nilssen, Nicolay Rustad & Sollid, Ludvig Magne [Vis alle 8 forfattere av denne artikkelen] (2018). Soluble T-cell receptor design influences functional yield in an E. coli chaperone-assisted expression system. PLOS ONE. ISSN 1932-6203. 13:e0195868(4), s. 1–15. doi: 10.1371/journal.pone.0195868. Fulltekst i vitenarkiv Vis sammendrag

  There is a quest for production of soluble protein of high quality for the study of T-cell receptors (TCRs), but expression often results in low yields of functional molecules. In this study, we used an E. coli chaperone-assisted periplasmic production system and compared expression of 4 different soluble TCR formats: single-chain TCR (scTCR), two different disulfide-linked TCR (dsTCR) formats, and chimeric Fab (cFab). A stabilized version of scTCR was also included. Additionally, we evaluated the influence of host (XL1-Blue or RosettaBlueTM) and the effect of IPTG induction on expression profiles. A celiac disease patient-derived TCR with specificity for gluten was used, and we achieved detectable expression for all formats and variants. We found that expression in RosettaBlueTM without IPTG induction resulted in the highest periplasmic yields. Moreover, after large-scale expression and protein purification, only the scTCR format was obtained in high yields. Importantly, stability engineering of the scTCR was a prerequisite for obtaining reliable biophysical characterization of the TCR-pMHC interaction. The scTCR format is readily compatible with high-throughput screening approaches that may enable both development of reagents allowing for defined peptide MHC (pMHC) characterization and discovery of potential novel therapeutic leads.

• Snir, Omri; Chen, Xi; Gidoni, Moriah; du Pré, Marie Fleur; Zhao, Yuguang & Steinsbø, Øyvind [Vis alle 9 forfattere av denne artikkelen] (2017). Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight. ISSN 2379-3708. 2(16). doi: 10.1172/jci.insight.93961. Fulltekst i vitenarkiv
• Sarna, Vikas Kumar; Skodje, Gry Irene; Reims, Henrik Mikael; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva & Sollid, Ludvig Magne [Vis alle 7 forfattere av denne artikkelen] (2017). HLA-DQ:gluten tetramer test in blood gives better detection of coeliac patients than biopsy after 14-day gluten challenge. Gut. ISSN 0017-5749. 67(9), s. 1606–1613. doi: 10.1136/gutjnl-2017-314461. Fulltekst i vitenarkiv
• Sarna, Vikas Kumar; Lundin, Knut Erik Aslaksen; Mørkrid, Lars; Qiao, Shuo Wang; Sollid, Ludvig Magne & Christophersen, Asbjørn (2017). HLA-DQ-gluten tetramer blood test accurately identifies patients with and without celiac disease in absence of gluten consumption. Gastroenterology. ISSN 0016-5085. 154(4), s. 886–896.e6. doi: 10.1053/j.gastro.2017.11.006. Fulltekst i vitenarkiv
• Viken, Marte K; Flåm, Siri Tennebø; Skrivarhaug, Torild; Amundsen, Silja Svanstrøm; Sollid, Ludvig Magne & Drivvoll, Ann Kristin [Vis alle 9 forfattere av denne artikkelen] (2017). HLA class II alleles in Norwegian patients with coexisting type 1 diabetes and celiac disease. HLA. ISSN 2059-2302. 89(5), s. 278–284. doi: 10.1111/tan.12986.
• Raki, Melinda; Dahal-Koirala, Shiva; Yu, Hao; Korponay-Szabó, Ilma R.; Gyimesi, Judit & Castillejo, Gemma [Vis alle 9 forfattere av denne artikkelen] (2017). Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes. Gastroenterology. ISSN 0016-5085. 153(3), s. 787–798.e4. doi: 10.1053/j.gastro.2017.05.016.
• Iversen, Rasmus; Snir, Omri; Stensland, Maria; Kroll, José E.; Steinsbø, Øyvind & Korponay-Szabó, Ilma R. [Vis alle 9 forfattere av denne artikkelen] (2017). Strong clonal relatedness between serum and gut IgA despite different plasma cell origins. Cell reports. ISSN 2211-1247. 20(10), s. 2357–2367. doi: 10.1016/j.celrep.2017.08.036. Fulltekst i vitenarkiv
• Gunnarsen, Kristin Støen; Høydahl, Lene Støkken; Risnes, Louise Fremgaard; Dahal-Koirala, Shiva; Neumann, Ralf Stefan & Bergseng, Elin [Vis alle 15 forfattere av denne artikkelen] (2017). A TCRα framework–centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions. JCI Insight. ISSN 2379-3708. 2(17). doi: 10.1172/jci.insight.95193. Fulltekst i vitenarkiv
• Goel, Gautam; King, Tim; Daveson, A. James; Andrews, Jane M.; Krishnarajah, Janakan & Krause, Richard [Vis alle 28 forfattere av denne artikkelen] (2017). Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies. The Lancet Gastroenterology and Hepatology. ISSN 2468-1253. 2(7), s. 479–493. doi: 10.1016/S2468-1253%2817%2930110-3. Fulltekst i vitenarkiv
• Sollid, Ludvig Magne (2017). The roles of MHC class II genes and post-translational modification in celiac disease. Immunogenetics. ISSN 0093-7711. 69(8-9), s. 605–616. doi: 10.1007/s00251-017-0985-7. Fulltekst i vitenarkiv
• Jabri, Bana & Sollid, Ludvig Magne (2017). T cells in celiac disease. Journal of Immunology. ISSN 0022-1767. 198(8), s. 3005–3014. doi: 10.4049/jimmunol.1601693.
• Nguyen, Thanh-Binh; Jayaraman, Priya; Bergseng, Elin; Madhusudhan, M.S.; Kim, Chu-Young & Sollid, Ludvig Magne (2017). Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-Associated invariant chain peptides. Journal of Biological Chemistry. ISSN 0021-9258. 292(22), s. 9218–9228. doi: 10.1074/jbc.M117.785139.
• Roy, Bishnudeo; Neumann, Ralf Stefan; Snir, Omri; Iversen, Rasmus; Sandve, Geir Kjetil & Lundin, Knut Erik Aslaksen [Vis alle 7 forfattere av denne artikkelen] (2017). High-Throughput Single-Cell Analysis of B Cell Receptor Usage among Autoantigen-Specific Plasma Cells in Celiac Disease. Journal of Immunology. ISSN 0022-1767. 199((2)), s. 782–791. doi: 10.4049/jimmunol.1700169. Fulltekst i vitenarkiv
• Landsverk, Ole J. B.; Snir, Omri; Bartolome Casado, Raquel; Richter, Lisa Maria; Mold, Jeff E. & Réu, Pedro [Vis alle 18 forfattere av denne artikkelen] (2017). Antibody-secreting plasma cells persist for decades in human intestine. Journal of Experimental Medicine (JEM). ISSN 0022-1007. 214(2), s. 309–317. doi: 10.1084/jem.20161590. Fulltekst i vitenarkiv
• Cardoso, Ines Do Rosario; Østerlund, Eva Christina; Stamnæs, Jorunn; Iversen, Rasmus; Andersen, Jan Terje & Jørgensen, Thomas J D [Vis alle 7 forfattere av denne artikkelen] (2017). Dissecting the interaction between transglutaminase 2 and fibronectin. Amino Acids. ISSN 0939-4451. 49(3), s. 489–500. doi: 10.1007/s00726-016-2296-y. Fulltekst i vitenarkiv
• Hnida, Kathrin; Stamnæs, Jorunn; du Pré, Marie Fleur; Mysling, Simon; Jørgensen, Thomas J D & Sollid, Ludvig Magne [Vis alle 7 forfattere av denne artikkelen] (2016). Epitope-dependent functional effects of celiac disease autoantibodies on transglutaminase 2. Journal of Biological Chemistry. ISSN 0021-9258. 291(49), s. 25542–25552. doi: 10.1074/jbc.M116.738161.
• Høydahl, Lene Støkken; Nilssen, Nicolay Rustad; Gunnarsen, Kristin Støen; du Pré, Marie Fleur; Iversen, Rasmus & Roos, Norbert [Vis alle 11 forfattere av denne artikkelen] (2016). Multivalent pIX phage display selects for distinct and improved antibody properties. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep39066. Fulltekst i vitenarkiv
• Stamnæs, Jorunn; Cardoso, Ines Do Rosario; Iversen, Rasmus & Sollid, Ludvig Magne (2016). Transglutaminase 2 strongly binds to an extracellular matrix component other than fibronectin via its second C-terminal beta-barrel domain. The FEBS Journal. ISSN 1742-464X. 283(21), s. 3994–4010. doi: 10.1111/febs.13907.
• Spencer, Jo M. & Sollid, Ludvig Magne (2016). The human intestinal B-cell response. Mucosal Immunology. ISSN 1933-0219. 9(5), s. 1113–1124. doi: 10.1038/mi.2016.59.
• Dahal-Koirala, Shiva; Risnes, Louise Fremgaard; Christophersen, Asbjørn; Sarna, Vikas Kumar; Lundin, Knut Erik Aslaksen & Sollid, Ludvig Magne [Vis alle 7 forfattere av denne artikkelen] (2016). TCR sequencing of single cells reactive to DQ2.5-glia-α2 and DQ2.5-glia-ω2 reveals clonal expansion and epitope-specific V-gene usage. Mucosal Immunology. ISSN 1933-0219. 9(3), s. 587–596. doi: 10.1038/mi.2015.147. Fulltekst i vitenarkiv
• Christophersen, Asbjørn; Risnes, Louise Fremgaard; Bergseng, Elin; Lundin, Knut Erik Aslaksen; Sollid, Ludvig Magne & Qiao, Shuo Wang (2016). Healthy HLA-DQ2.5<sup>+</sup> subjects lack regulatory and memory T cells specific for immunodominant gluten epitopes of celiac disease. Journal of Immunology. ISSN 0022-1767. 196(6), s. 2819–2826. doi: 10.4049/jimmunol.1501152.
• Dørum, Siri; Steinsbø, Øyvind; Bergseng, Elin; Arntzen, Magnus Øverlie; De Souza, Gustavo Antonio & Sollid, Ludvig Magne (2016). Gluten-specific antibodies of celiac disease gut plasma cells recognize long proteolytic fragments that typically harbor T-cell epitopes. Scientific Reports. ISSN 2045-2322. 6. doi: 10.1038/srep25565. Fulltekst i vitenarkiv
• Riaz, Tahira; Sollid, Ludvig Magne; Olsen, Ingrid & De Souza, Gustavo Antonio (2016). Quantitative Proteomics of Gut-Derived Th1 and Th1/Th17 Clones Reveal the Presence of CD28+ NKG2D- Th1 Cytotoxic CD4+ T cells. Molecular & Cellular Proteomics. ISSN 1535-9476. 15(3), s. 1007–1016. doi: 10.1074/mcp.M115.050138.
• De Niro, R; Snir, Omri; Kaukinen, Katri; Yaari, Gur; Lundin, Knut Erik Aslaksen & Gupta, N [Vis alle 12 forfattere av denne artikkelen] (2016). Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease. Mucosal Immunology. ISSN 1933-0219. 9, s. 254–264. doi: 10.1038/mi.2015.57.
• Iversen, Rasmus; Fleur du Pre, Marie; Di Niro, Roberto & Sollid, Ludvig Magne (2015). Igs as substrates for transglutaminase 2: Implications for autoantibody production in celiac disease. Journal of Immunology. ISSN 0022-1767. 195(11), s. 5159–5168. doi: 10.4049/jimmunol.1501363. Fulltekst i vitenarkiv Vis sammendrag

  Autoantibodies specific for the enzyme transglutaminase 2 (TG2) are a hallmark of the gluten-sensitive enteropathy celiac disease. Production of the Abs is strictly dependent on exposure to dietary gluten proteins, thus raising the question how a foreign Ag (gluten) can induce an autoimmune response. It has been suggested that TG2-reactive B cells are activated by gluten-reactive T cells following receptor-mediated uptake of TG2-gluten complexes. In this study, we propose a revised model that is based on the ability of the BCR to serve as a substrate to TG2 and become cross-linked to gluten-derived peptides. We show that TG2-specific IgD molecules are preferred in the reaction and that binding of TG2 via a common epitope targeted by cells using the IgH variable gene segment (IGHV)5-51 results in more efficient cross-linking. Based on these findings we hypothesize that IgD-expressing B cells using IGHV5-51 are preferentially activated, and we suggest that this property can explain the previously reported low number of somatic mutations as well as the overrepresentation of IGHV5-51 among TG2-specific plasma cells in the celiac lesion. The model also couples gluten peptide uptake by TG2-reactive B cells directly to peptide deamidation, which is necessary for the activation of gluten-reactive T cells. It thereby provides a link between gluten deamidation, T cell activation, and the production of TG2-specific Abs. These are all key events in the development of celiac disease, and by connecting them the model may explain why the same enzyme that catalyzes gluten deamidation is also an autoantigen, something that is hardly coincidental

• Steinsbø, Øyvind; Dørum, Siri; Lundin, Knut Erik Aslaksen & Sollid, Ludvig Magne (2015). Serologic assay for diagnosis of celiac disease based on a patient-derived monoclonal antigliadin antibody. Gastroenterology. ISSN 0016-5085. 149(6), s. 1530–1540.e3. doi: 10.1053/j.gastro.2015.07.008.
• du Pré, Fleur & Sollid, Ludvig Magne (2015). T-cell and B-cell immunity in celiac disease. Baillière's Best Practice & Research : Clinical Gastroenterology. ISSN 1521-6918. 29(3), s. 413–423. doi: 10.1016/j.bpg.2015.04.001.
• Stamnæs, Jorunn & Sollid, Ludvig Magne (2015). Celiac disease: Autoimmunity in response to food antigen. Seminars in Immunology. ISSN 1044-5323. 27(5), s. 343–352. doi: 10.1016/j.smim.2015.11.001.
• Stamnæs, Jorunn; Iversen, Rasmus; Fleur du Pre, Marie; Xi, Chien & Sollid, Ludvig Magne (2015). Enhanced B-cell receptor recognition of the autoantigen transglutaminase 2 by efficient catalytic self-multimerization. PLOS ONE. ISSN 1932-6203. 10:e0134922(8). doi: 10.1371/journal.pone.0134922.
• Cardoso, Ines Do Rosario; Stamnæs, Jorunn; Andersen, Jan Terje; Melino, Gerry; Iversen, Rasmus & Sollid, Ludvig Magne (2015). Transglutaminase 2 interactions with extracellular matrix proteins as probed with celiac disease autoantibodies. The FEBS Journal. ISSN 1742-464X. s. 2063–2075. doi: 10.1111/febs.13276.
• Xi, Chien; Hnida, Kathrin; Graewert, Melissa Ann; Andersen, Jan Terje; Iversen, Rasmus & Tuukkanen, Anne [Vis alle 8 forfattere av denne artikkelen] (2015). Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease. Journal of Biological Chemistry. ISSN 0021-9258. 290(35), s. 21365–21375. doi: 10.1074/jbc.M115.669895.
• Snir, Omri; Mesin, Luka; Gidoni, Moriah; Lundin, Knut E A; Yaari, Gur & Sollid, Ludvig Magne (2015). Analysis of celiac disease autoreactive gut plasma cells and their corresponding memory compartment in peripheral blood using high-throughput sequencing. Journal of Immunology. ISSN 0022-1767. 194(12), s. 5703–5712. doi: 10.4049/jimmunol.1402611.

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• Andersen, Ina Lervåg; Klaasen, Rolf Anton; Warren, David; Lukina, Polina; Mjønes, Patricia & Rønne, Elin [Vis alle 11 forfattere av denne artikkelen] (2022). Screening for adult celiac disease in the general population.
• Andersen, Ina Lervåg; Klaasen, Rolf; Warren, David; Lukina, Polina; Mjønes, Patricia & Rønne, Elin [Vis alle 11 forfattere av denne artikkelen] (2022). Screening for cøliaki i den voksne befolkningen.
• Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg & Mjønes, Patricia [Vis alle 10 forfattere av denne artikkelen] (2022). The development and validation of a high-capacity serological assay for coeliac disease.
• Lukina, Polina; Andersen, Ina Lervåg; Hjort, Rebecka; Eggen, Petter Tinbod; Næss, Marit & Mjønes, Patricia [Vis alle 20 forfattere av denne artikkelen] (2022). Cøliaki i HUNT. Forekomst, konsekvenser og årsaker.
• Risnes, Louise Fremgaard; Eggesbø, Linn Margrethe; Christophersen, Asbjørn Otto & Sollid, Ludvig Magne (2021). Response to: “Some considerations about γδ and CD8+ T-cell responses in blood after gluten challenge in treated celiac disease”. Mucosal Immunology. ISSN 1933-0219. 14(5), s. 1216–1217. doi: 10.1038/s41385-021-00422-6.
• Eggesbø, Linn Margrethe; Risnes, Louise Fremgaard; Neumann, Ralf Stefan; Lundin, Knut E. A.; Christophersen, Asbjørn Otto & Sollid, Ludvig Magne (2021). Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8⁺ αβ T lymphocytes in untreated celiac disease. European Journal of Immunology. ISSN 0014-2980. 51(6), s. 1542–1545. doi: 10.1002/eji.202048974.
• Sollid, Ludvig Magne & Koning, Frits (2021). Lack of relationship of AT1001 to zonulin and prehaptoglobin-2: Clinical implications. Gut. ISSN 0017-5749. 70(11), s. 2211–2212. doi: 10.1136/gutjnl-2020-323829.
• Sollid, Ludvig Magne; Lundin, Knut Erik Aslaksen; Leivestad, Torbjørn; Spurkland, Anne & Vartdal, Frode (2021). Erik Thorsby (1938-2021). Immunogenetics. ISSN 0093-7711. 73(3), s. 203–205. doi: 10.1007/s00251-021-01218-5.
• Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg & Mjønes, Patricia [Vis alle 10 forfattere av denne artikkelen] (2021). THE DEVELOPMENT AND VALIDATION OF A HIGH-CAPACITY SEROLOGICAL ASSAY FOR COELIAC DISEASE .
• Andersen, Ina Lervåg; Klaasen, Rolf Anton; Warren, David; Lukina, Polina; Mjønes, Patricia & Rønne, Elin [Vis alle 11 forfattere av denne artikkelen] (2021). Screening for adult coeliac disease in the general population.
• Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg & Mjønes, Patricia [Vis alle 10 forfattere av denne artikkelen] (2021). THE DEVELOPMENT AND VALIDATION OF A HIGH-CAPACITY SEROLOGICAL ASSAY FOR COELIAC DISEASE. United European Gastroenterology journal. ISSN 2050-6406. 9, s. 348–348.
• Andersen, Ina Lervåg; Klaasen, Rolf; Warren, David; Lukina, Polina; Mjønes, Patricia & Rønne, Elin [Vis alle 11 forfattere av denne artikkelen] (2021). SCREENING FOR ADULT COELIAC DISEASE IN THE GENERAL POPULATION. United European Gastroenterology journal. ISSN 2050-6406. 9, s. 354–355.
• Klaasen, Rolf; Warren, David; Iversen, Rasmus; Bolstad, Nils; Andersen, Ina Lervåg & Mjønes, Patricia [Vis alle 10 forfattere av denne artikkelen] (2021). THE DEVELOPMENT AND VALIDATION OF A HIGH-CAPACITY SEROLOGICAL ASSAY FOR COELIAC DISEASE.
• Andersen, Ina Lervåg; Klaasen, Rolf; Warren, David; Lukina, Polina; Mjønes, Patricia & Rønne, Elin [Vis alle 11 forfattere av denne artikkelen] (2021). SCREENING FOR ADULT COELIAC DISEASE IN THE GENERAL POPULATION.
• Lindstad, Christian Borgen; Qiao, Shuo Wang; Johansen, Marie Kongshaug; Fugger, Lars; Sollid, Ludvig Magne & du Pré, Marie Fleur (2020). Characterization of T‐cell receptor transgenic mice recognizing immunodominant HLA‐DQ2.5‐restricted gluten epitopes. European Journal of Immunology. ISSN 0014-2980. 00(0), s. 1–4. doi: 10.1002/eji.202048859.
• Iversen, Rasmus; Amundsen, Sunniva Furre; Kleppa, Liv; du Pré, Marie Fleur; Stamnæs, Jorunn & Sollid, Ludvig Magne (2020). Evidence that pathogenic transglutaminase 2 in celiac disease derives from enterocytes . Gastroenterology. ISSN 0016-5085. 159(2), s. 788–790. doi: 10.1053/j.gastro.2020.04.018.
• Lindeman, Ida; Emerton, Guy; Mamanova, Lira; Snir, Omri; Polanski, Krzysztof & Qiao, Shuo Wang [Vis alle 9 forfattere av denne artikkelen] (2018). BraCeR: B-cell-receptor reconstruction and clonality inference from single-cell RNA-seq. Nature Methods. ISSN 1548-7091. 15(8), s. 563–565. doi: 10.1038/s41592-018-0082-3. Fulltekst i vitenarkiv
• Sollid, Ludvig Magne & Lycke, Nils (2017). Per Brandtzaeg: patron of mucosal immunology. Mucosal Immunology. ISSN 1933-0219. 10, s. 1–4. doi: 10.1038/mi.2016.111.

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