Johanna Olweus

Nedenfor liste over utvalgte publikasjoner.

Fullstendig publikasjonsliste her.

• Strønen E, Toebes M, Kelderman S, van Buuren MM, Yang W, van Rooij N, Donia M, Böschen ML, Lund-Johansen F, Olweus J, Schumacher TN.Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science. 2016 May 19. pii: aaf2288. [Epub ahead of print] PMID: 27198675

• Kolstad A, Kumari S, Walczak M, Madsbu U, Hagtvedt T, Bogsrud TV, Kvalheim G, Holte H, Aurlien E, Delabie J, Tierens A, Olweus J. Sequential intranodal immuntherapy induces anti-tumor immunity and correlated regression of disseminated follicular lymphoma. Blood 2014 Oct 7 pii: blood-2014-07-592162. [Epub ahead of print]
• Kumari S, Walchli S, Fallang LE, Yang W, Lund-Johansen F, Schumacher TN, Olweus J. Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes. Proc Natl Acad Sci U S A. 2014;111(1):403-408.
  Selected by Faculty of 1000 Prime:http://f1000.com/prime/718206020?bd=1 (Two stars)
• Lossius A, Johansen JN, Vartdal F, Robins H, Benth JS, Holmoy T, Olweus J. High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8 T cells. Eur J Immunol. 2014.
• Walchli S, Kumari S, Fallang LE, Sand KM, Yang W, Landsverk OJ, . . . Olweus J*, Gregers TF*. Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. Eur J Immunol. 2014;44(3):774-784.
   *Shared senior authors. Front cover. Commentary in Eur J Immunol 2014, V44, p650
  Selected by Faculty of 1000 Prime: http://f1000.com/prime/718194774?bd=1&ui=28053
• Taraldsrud E, Fevang B, Aukrust P, Beiske KH, Floisand Y, Froland S, . . . Olweus J. Common variable immunodeficiency revisited: normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9. 
  Clin Exp Immunol. 2014;175(3):439-448.
• Abrahamsen IW, Kjellevoll S, Greve-Isdahl M, Mensali N, Walchli S, Kumari S, . . . Olweus J. T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells. Int J Cancer. 2012;130(8):1821-1832.
• Abrahamsen IW, Stronen E, Walchli S, Johansen JN, Kjellevoll S, Kumari S, . . . Olweus J. Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif. Leukemia. 2010;24(11):1901-1909.

• Spasevska, Ivana; Sharma, Ankush; Steen, Chloe Beate; Josefsson, Sarah Elisabet; Blaker, Yngvild Nuvin & Kolstad, Arne [Vis alle 26 forfattere av denne artikkelen] (2023). Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma. Blood Advances. ISSN 2473-9529. 7(23), s. 7216–7230. doi: 10.1182/bloodadvances.2023010158. Fulltekst i vitenarkiv
• Giannakopoulou, Eirini Chrysovalantou; Lehander, Madeleine; Virding Culleton, Stina; Yang, Weiwen; Li, Yingqian & Kärpänen, Terhi Hannele [Vis alle 29 forfattere av denne artikkelen] (2023). A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo. Nature Cancer. 4(10). doi: 10.1038/s43018-023-00642-8. Fulltekst i vitenarkiv
• Földvári, Zsofia; Knetter, Cathrine; Yang, Weiwen; Gjerdingen, Thea Johanne; Bollineni, Ravi Chand & Tran, Trung [Vis alle 12 forfattere av denne artikkelen] (2023). A systematic safety pipeline for selection of T-cell receptors to enter clinical use. npj Vaccines. ISSN 2059-0105. 8(1). doi: 10.1038/s41541-023-00713-y.
• Meyer, Saskia; Blaas, Isaac; Bollineni, Ravi Chand; Delic-Sarac, Marina; Tran, Trung & Knetter, Cathrine [Vis alle 20 forfattere av denne artikkelen] (2023). Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants. Cell reports. ISSN 2211-1247. 42(1). doi: 10.1016/j.celrep.2023.111995. Fulltekst i vitenarkiv
• Pataskar, Abhijeet; Champagne, Julien; Nagel, Remco; Kenski, Juliana; Laos, Maarja & Michaux, Justine [Vis alle 24 forfattere av denne artikkelen] (2022). Tryptophan depletion results in tryptophan-to-phenylalanine substitutants. Nature. ISSN 0028-0836. 603(7902), s. 721–727. doi: 10.1038/s41586-022-04499-2. Fulltekst i vitenarkiv
• Bollineni, Ravi Chand; Tran, Trung; Lund-Johansen, Fridtjof & Olweus, Johanna (2022). Chasing neoantigens; invite naïve T cells to the party. Current Opinion in Immunology. ISSN 0952-7915. 75, s. 1–7. doi: 10.1016/j.coi.2022.102172.
• Riise, Jon; Meyer, Saskia; Blaas, Isaac; Chopra, Adity; Tran, Trung & Delic-Sarac, Marina [Vis alle 22 forfattere av denne artikkelen] (2022). Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination. British Journal of Haematology. ISSN 0007-1048. 197(6), s. 697–708. doi: 10.1111/bjh.18149. Fulltekst i vitenarkiv Vis sammendrag

  B-cell depletion induced by anti-cluster of differentiation 20 (CD20) monoclonal antibody (mAb) therapy of patients with lymphoma is expected to impair humoral responses to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination, but effects on CD8 T-cell responses are unknown. Here, we investigated humoral and CD8 T-cell responses following two vaccinations in patients with lymphoma undergoing anti-CD20-mAb therapy as single agent or in combination with chemotherapy or other anti-neoplastic agents during the last 9 months prior to inclusion, and in healthy age-matched blood donors. Antibody measurements showed that seven of 110 patients had antibodies to the receptor-binding domain of the SARS-CoV-2 Spike protein 3–6 weeks after the second dose of vaccination. Peripheral blood CD8 T-cell responses against prevalent human leucocyte antigen (HLA) class I SARS-CoV-2 epitopes were determined by peptide-HLA multimer analysis. Strong CD8 T-cell responses were observed in samples from 20/29 patients (69%) and 12/16 (75%) controls, with similar median response magnitudes in the groups and some of the strongest responses observed in patients. We conclude that despite the absence of humoral immune responses in fully SARS-CoV-2-vaccinated, anti-CD20-treated patients with lymphoma, their CD8 T-cell responses reach similar frequencies and magnitudes as for controls. Patients with lymphoma on B-cell depleting therapies are thus likely to benefit from current coronavirus disease 2019 (COVID-19) vaccines, and development of vaccines aimed at eliciting T-cell responses to non-Spike epitopes might provide improved protection.

• Ali, Muhammad; Giannakopoulou, Eirini Chrysovalantou; Li, Yingqian; Lehander, Madeleine; Virding Culleton, Stina & Yang, Weiwen [Vis alle 33 forfattere av denne artikkelen] (2021). T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes. Nature Biotechnology. ISSN 1087-0156. doi: 10.1038/s41587-021-01089-x. Fulltekst i vitenarkiv
• Mazzarella, Luca; Enblad, Gunilla; Olweus, Johanna; Malmberg, Karl-Johan & Jerkeman, Mats (2021). Advances in immune therapies in hematological malignancies. Journal of Internal Medicine. ISSN 0954-6820. s. 1–16. doi: 10.1111/joim.13395. Fulltekst i vitenarkiv
• Ask, Eivind Heggernes; Tschan-Plessl, Astrid; Gjerdingen, Thea Johanne; Hoel, Hanna Julie; Sætersmoen, Michelle Lu & Wiiger, Merete Thune [Vis alle 16 forfattere av denne artikkelen] (2021). A Systemic Protein Deviation Score Linked to PD-1+ CD8+ T Cell Expansion That Predicts Overall Survival in Diffuse Large B Cell Lymphoma. Med. ISSN 2666-6359. 2(2), s. 180–195. doi: 10.1016/j.medj.2020.10.006.
• Bartok, Osnat; Pataskar, Abhijeet; Nagel, Remco; Laos, Maarja; Goldfarb, Eden & Hayoun, Deborah [Vis alle 30 forfattere av denne artikkelen] (2020). Anti-tumour immunity induces aberrant peptide presentation in melanoma. Nature. ISSN 0028-0836. 590, s. 332–337. doi: 10.1038/s41586-020-03054-1.
• Muhammad, Ali; Földvári, Zsofia; Giannakopoulou, Eirini Chrysovalantou; Bøschen, Maxi-Lu; Strønen, Erlend & Yang, Weiwen [Vis alle 11 forfattere av denne artikkelen] (2019). Induction of neoantigen-reactive T cells from healthy donors. Nature Protocols. ISSN 1754-2189. 14(6), s. 1926–1943. doi: 10.1038/s41596-019-0170-6.
• Oei, Vincent Yi Sheng; Siernicka, Marta; Graczyk-Jarzynka, Agnieszka; Hoel, Hanna Julie; Yang, Weiwen & Palacios Orellana, Daniel Alfredo [Vis alle 17 forfattere av denne artikkelen] (2018). Intrinsic functional potential of NK-Cell subsets constrains retargeting driven by chimeric antigen receptors. Cancer immunology research. ISSN 2326-6066. 6(4), s. 467–480. doi: 10.1158/2326-6066.CIR-17-0207. Fulltekst i vitenarkiv
• Kärpänen, Terhi Hannele & Olweus, Johanna (2017). The Potential of Donor T-Cell Repertoires in Neoantigen-Targeted Cancer Immunotherapy. Frontiers in Immunology. ISSN 1664-3224. doi: 10.3389/fimmu.2017.01718. Vis sammendrag

  T cells can recognize peptides encoded by mutated genes, but analysis of tumor-infiltrating lymphocytes suggests that very few neoantigens spontaneously elicit T-cell responses. This may be an important reason why immune checkpoint inhibitors are mainly effective in tumors with a high mutational burden. Reasons for clinically insufficient responses to neoantigens might be inefficient priming, inhibition, or deletion of the cognate T cells. Responses can be dramatically improved by cancer immunotherapy such as checkpoint inhibition, but often with temporary effects. By contrast, T cells from human leukocyte antigen (HLA)-matched donors can cure diseases such as chronic myeloid leukemia. The therapeutic effect is mediated by donor T cells recognizing polymorphic peptides for which the donor and patient are disparate, presented on self-HLA. Donor T-cell repertoires are unbiased by the immunosuppressive environment of the tumor. A recent study demonstrated that T cells from healthy individuals are able to respond to neoantigens that are ignored by tumor-infiltrating T cells of melanoma patients. In this review, we discuss possible reasons why neoantigens escape host T cells and how these limitations may be overcome by utilization of donor-derived T-cell repertoires to facilitate rational design of neoantigen-targeted immunotherapy.

• Olweus, Johanna (2017). Manufacture of CAR-T cells in the body. Nature Biotechnology. ISSN 1087-0156. 35(6), s. 520–521. doi: 10.1038/nbt.3898.
• Taraldsrud, Eli; Fevang, Børre; Jørgensen, Silje Fjellgård; Moltu, Kristine; Hilden, Vera Irene & Tasken, Kjetil [Vis alle 9 forfattere av denne artikkelen] (2017). Defective IL-4 signaling in T cells defines severe common variable immunodeficiency. Journal of Autoimmunity. ISSN 0896-8411. 81, s. 110–119. doi: 10.1016/j.jaut.2017.04.004.
• Henriksen, Eva Kristine Klemsdal; Jørgensen, Kristin Kaasen; Kaveh, Fatemeh; Holm, Kristian; Hamm, David & Olweus, Johanna [Vis alle 14 forfattere av denne artikkelen] (2017). Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease. Journal of Hepatology. ISSN 0168-8278. 66(1), s. 116–122. doi: 10.1016/j.jhep.2016.09.002.
• Taraldsrud, Eli; Aukrust, Pål; Jørgensen, Silje Fjellgård; Lingjærde, Ole Christian; Olweus, Johanna & Myklebust, June [Vis alle 7 forfattere av denne artikkelen] (2017). Patterns of constitutively phosphorylated kinases in B cells are associated with disease severity in common variable immunodeficiency. Clinical Immunology. ISSN 1521-6616. 175, s. 69–74. doi: 10.1016/j.clim.2016.11.014. Vis sammendrag

  Patients with common variable immunodeficiency (CVID) constitute a clinically and immunologically heterogeneous group characterized by B-cell dysfunction with hypogammaglobulinemia and defective immunoglobulin class switch of unknown etiology. Current classification systems are insufficient to achieve precise disease management. Characterization of signaling pathways essential for B-cell differentiation and class switch could provide new means to stratify patients. We evaluated constitutive and induced signaling by phospho-specific flow cytometry in 26 CVID patients and 18 healthy blood donors. Strong responses were induced both in CVID and healthy donor B cells upon activation. In contrast, constitutive phosphorylation levels of STAT3,-5,-6, Erk, PLC-γ and Syk were significantly increased in CVID B cells only. Hierarchical clustering revealed a subgroup of CVID patients with elevated constitutive phosphorylation of Syk and PLC-γ. All these patients had non-infectious complications, indicating that a distinct phosphorylation pattern of kinases in B cells identifies a clinically important subgroup of CVID patients.

• Mensali, Nadia; Fan, Ying; Oei, Vincent Yi Sheng; Yang, Weiwen; Walseng, Even & Kumari, Shraddha [Vis alle 12 forfattere av denne artikkelen] (2016). Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA. Oncoimmunology. ISSN 2162-4011. 5:e1138100(5). doi: 10.1080/2162402X.2016.1138199.
• Strønen, Erlend; Toebes, Mireille; Kelderman, Sander; van Buuren, Marit M.; Yang, Weiwen & Van Rooij, Nienke [Vis alle 11 forfattere av denne artikkelen] (2016). Targeting of cancer neoantigens with donor-derived T cell receptor repertoires. Science. ISSN 0036-8075. 352(6291), s. 1337–1341. doi: 10.1126/science.aaf2288.
• Liaskou, Evaggelia; Henriksen, Eva Kristine Klemsdal; Holm, Kristian; Kaveh, Fatemeh; Hamm, D & Fear, Janine [Vis alle 13 forfattere av denne artikkelen] (2016). High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires. Hepatology. ISSN 0270-9139. 63(5), s. 1608–1619. doi: 10.1002/hep.28116. Vis sammendrag

  Hepatic T-cell infiltrates and a strong genetic human leukocyte antigen association represent characteristic features of various immune-mediated liver diseases. Conceptually the presence of disease-associated antigens is predicted to be reflected in T-cell receptor (TCR) repertoires. Here, we aimed to determine if disease-associated TCRs could be identified in the nonviral chronic liver diseases primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and alcoholic liver disease (ALD). We performed high-throughput sequencing of the TCRβ chain complementarity-determining region 3 of liver-infiltrating T cells from PSC (n = 20), PBC (n = 10), and ALD (n = 10) patients, alongside genomic human leukocyte antigen typing. The frequency of TCRβ nucleotide sequences was significantly higher in PSC samples (2.53 ± 0.80, mean ± standard error of the mean) compared to PBC samples (1.13 ± 0.17, P < 0.0001) and ALD samples (0.62 ± 0.10, P < 0.0001). An average clonotype overlap of 0.85% was detected among PSC samples, significantly higher compared to the average overlap of 0.77% seen within the PBC (P = 0.024) and ALD groups (0.40%, P < 0.0001). From eight to 42 clonotypes were uniquely detected in each of the three disease groups (≥30% of the respective patient samples). Multiple, unique sequences using different variable family genes encoded the same amino acid clonotypes, providing additional support for antigen-driven selection. In PSC and PBC, disease-associated clonotypes were detected among patients with human leukocyte antigen susceptibility alleles. Conclusion: We demonstrate liver-infiltrating disease–associated clonotypes in all three diseases evaluated, and evidence for antigen-driven clonal expansions. Our findings indicate that differential TCR signatures, as determined by high-throughput sequencing, may represent an imprint of distinctive antigenic repertoires present in the different chronic liver diseases; this thereby opens up the prospect of studying disease-relevant T cells in order to better understand and treat liver disease. (Hepatology 2015)

• Kärpänen, Terhi Hannele & Olweus, Johanna (2015). T-cell receptor gene therapy - ready to go viral? Molecular Oncology. ISSN 1574-7891. 9(10), s. 2019–2042. doi: 10.1016/j.molonc.2015.10.006.
• Tadesse, Fitsum G.; Mensali, Nadia; Fallang, Lars-Egil; Walseng, Even; Yang, Weiwen & Olweus, Johanna [Vis alle 7 forfattere av denne artikkelen] (2015). Unpredicted phenotypes of two mutants of the TcR DMF5. Journal of Immunological Methods (JIM). ISSN 0022-1759. 425, s. 37–44. doi: 10.1016/j.jim.2015.06.006. Vis sammendrag

  When a T-cell Receptor (TcR) interacts with its cognate peptide-MHC (pMHC), it triggers activation of a signaling cascade that results in the elicitation of a T cell effector function. Different models have been proposed to understand which parameters are needed to obtain an optimal activation of the signaling. It was speculated that improving the binding of a TcR could bring a stronger pMHC recognition, hence a stronger stimulation of the T cell. However, it was recently shown that an increase in affinity does not seem to be sufficient to guarantee improved functionality. A combination of factors is necessary to place the modified TcR in an optimal functional window. We here compared the binding parameters of two mutants of the melanoma antigen peptide MART-127 − 35 specific TcR DMF5. The first mutant was previously isolated by others in a screen for improved TcR. It was reported to have an increased CD8-independent activity. We confirmed these data and showed that the enhancement was neither due to change in half life (t1/2) nor Kd of the pMHC-TcR complex. The second mutant was designed based on a previous report claiming that a particular polymorphic residue in the TRAV12-2 chain was stabilizing the TcR. We created a DMF5 mutant for this residue and showed that, unexpectedly, this TcR had acquired a reduced overall activity although the TcR-pMHC complex was more stable when compared to the TcR wild type complex (increased t1/2). In addition, the soluble TcR form of this mutant bound target cells less efficiently. From this we concluded that kinetic parameters do not always predict the superior functionality of mutant TcRs.

• Walseng, Even; Waelchli, Sebastien; Fallang, Lars-Egil; Yang, Weiwen; Vefferstad, Anette & Areffard, Mohammad Ali [Vis alle 7 forfattere av denne artikkelen] (2015). Soluble T-cell receptors produced in human cells for targeted delivery. PLOS ONE. ISSN 1932-6203. 10(4). doi: 10.1371/journal.pone.0119559.
• Kolstad, Arne; Kumari, Shraddha; Walczak, Mateusz; Madsbu, Ulf Erik; Hagtvedt, Trond & Bogsrud, Trond [Vis alle 12 forfattere av denne artikkelen] (2015). Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma. Blood. ISSN 0006-4971. 125(1), s. 82–89. doi: 10.1182/blood-2014-07-592162.
• Lossius, Peter Andreas Vold; Johansen, Jorunn; Vartdal, Frode; Robins, Harlan; Saltyte Benth, Jurate & Holmøy, Trygve [Vis alle 7 forfattere av denne artikkelen] (2014). High-throughput sequencing of TCR repertoires in multiple sclerosis reveals intrathecal enrichment of EBV-reactive CD8+ T cells. European Journal of Immunology. ISSN 0014-2980. 44(11), s. 3439–3452. doi: 10.1002/eji.201444662.
• Waelchli, Sebastien; Kumari, Shraddha; Fallang, Lars-Egil; Sand, Kine Marita Knudsen; Yang, Weiwen & Landsverk, Ole J. B. [Vis alle 9 forfattere av denne artikkelen] (2014). Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. European Journal of Immunology. ISSN 0014-2980. 44(3), s. 774–784. doi: 10.1002/eji.201343671.
• Taraldsrud, Eli; Fevang, Børre; Aukrust, Pål; Beiske, Klaus; Fløisand, Yngvar & Frøland, Stig Sophus [Vis alle 8 forfattere av denne artikkelen] (2014). Common variable immunodeficiency revisited: Normal generation of naturally occurring dendritic cells that respond to Toll-like receptors 7 and 9. Clinical and Experimental Immunology. ISSN 0009-9104. 175(3), s. 439–448. doi: 10.1111/cei.12239.
• Kumari, Shraddha; Waelchli, Sebastien; Fallang, Lars-Egil; Yang, Weiwen; Lund-Johansen, Fridtjof & Schumacher, Ton N. [Vis alle 7 forfattere av denne artikkelen] (2014). Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 111(1), s. 403–408. doi: 10.1073/pnas.1306549111.
• Abrahamsen, Ingerid Weum; Kjellevoll, Synneva; Greve-Isdahl, Margrethe; Mensali, Nadia; Waelchli, Sebastien & Kumari, Shraddha [Vis alle 10 forfattere av denne artikkelen] (2012). T cells raised against allogeneic HLA-A2/CD20 kill primary follicular lymphoma and acute lymphoblastic leukemia cells. International Journal of Cancer. ISSN 0020-7136. 130(8), s. 1821–1832. doi: 10.1002/ijc.26209.
• Wälchli, Sebastien; Løset, Geir Åge; Kumari, Shraddha; Johansen, Jorunn; Yang, Weiwen & Sandlie, Inger [Vis alle 7 forfattere av denne artikkelen] (2011). A Practical Approach to T-Cell Receptor Cloning and Expression. PLOS ONE. ISSN 1932-6203. 6(11). doi: 10.1371/journal.pone.0027930. Fulltekst i vitenarkiv
• Abrahamsen, Ingerid Weum; Strønen, Erlend; Waelchli, Sebastien; Johansen, Jorunn; Kumari, Shraddha & Komada, M [Vis alle 13 forfattere av denne artikkelen] (2010). Targeting B cell leukemia with highly specific allogeneic T cells with a public recognition motif. Leukemia. ISSN 0887-6924. 24(11), s. 1901–1909. doi: 10.1038/leu.2010.186.
• Rölle, Alexander & Olweus, Johanna (2009). Dendritic cells in cytomegalovirus infection: viral evasion and host countermeasures. APMIS - Journal of Pathologiy, Microbiology and Immunology. ISSN 0903-4641. 117(5-6), s. 413–426. doi: 10.1111/j.1600-0463.2009.02449.x.
• Strønen, Erlend; Abrahamsen, Ingerid Weum; Gaudernack, Gustav; Waelchli, Sebastien; Munthe, Else & Buus, S [Vis alle 9 forfattere av denne artikkelen] (2009). Dendritic Cells Engineered to Express Defined Allo-HLA Peptide Complexes Induce Antigen-specific Cytotoxic T Cells Efficiently Killing Tumour Cells. Scandinavian Journal of Immunology. ISSN 0300-9475. 69(4), s. 319–328. doi: 10.1111/j.1365-3083.2008.02223.x.
• Kvale, Espen Østhagen; Fløisand, Yngvar; Lund-Johansen, Fridtjof; Rollag, Halvor; Farkas, Lorant & Ghanekar, Smita [Vis alle 9 forfattere av denne artikkelen] (2007). Plasmacytoid DCs regulate recall responses by rapid induction of IL-10 in memory T cells. Blood. ISSN 0006-4971. 109. doi: 10.1182/blood-2006-06-031484.
• Villa, Iris Kristine; Kvale, Espen Østhagen; Lund-Johansen, Fridtjof & Olweus, Johanna (2007). Assay for monitoring in vitro selective depletion strategies in allogeneic stem cell transplantation. Cytotherapy. ISSN 1465-3249. 9, s. 600–610. doi: 10.1080/14653240701510573.
• Kvale, Espen Østhagen; Dalgaard, Jakob; Lund-Johansen, Fridtjof; Rollag, Halvor; Farkas, Lorant & Midtvedt, Karsten [Vis alle 9 forfattere av denne artikkelen] (2006). CD11c+ dendritic cells and plasmacytoid DCs are activated by human cytomegalovirus and retain efficient T cell–stimulatory capability upon infection. Blood. ISSN 0006-4971. 107(5), s. 2022–2029. doi: 10.1182/blood-2005-05-2016.

Se alle arbeider i Cristin

• Mamia, Katariina Aino Inkeri; Saarela, Janna Saija; Li, Zhuokun; Reint, Ganna; Fatkhutdinov, Nail & Haugen, Frida Høsøien [Vis alle 13 forfattere av denne artikkelen] (2022). CRISPR-Cas9 T cell editing pipeline for Finnish founder diseases.
• Pataskar, Abhijeet; Champagne, Julien; Nagel, Remco; Kenski, Juliana; Laos, Maarja & Michaux, Justine [Vis alle 24 forfattere av denne artikkelen] (2022). Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants (Nature, (2022), 603, 7902, (721-727), 10.1038/s41586-022-04499-2). Nature. ISSN 0028-0836. doi: 10.1038/s41586-022-05097-y.
• Olweus, Johanna & Lund-Johansen, Fridtjof (2019). Finding Neo (antigens, that is). Blood. ISSN 0006-4971. 134(2), s. 108–109. doi: 10.1182/blood.2019001334.
• Olweus, Johanna (2015). Cancer immunotherapy - Converting immune failure to clinical response. Molecular Oncology. ISSN 1574-7891. 9(10), s. 1891–1893. doi: 10.1016/j.molonc.2015.10.017.
• Kolstad, Arne & Olweus, Johanna (2015). “In situ” vaccination for systemic effects in follicular lymphoma. Oncoimmunology. ISSN 2162-4011. 4(7), s. 1–3. doi: 10.1080/2162402X.2015.1014773.
• Regenthal, P; Wälchli, S; Fallang, Lars-Egil; Olweus, Johanna & Lindkvist-Petersson, K (2013). Structural Modeling Provides Means to Understand the Binding Specificity of Alloreactive T Cells. Scandinavian Journal of Immunology. ISSN 0300-9475. 77(4), s. 314–315.
• Wälchli, Sebastien; Landsverk, Ole J. B.; Fallang, Lars-Egil; Olweus, Johanna; Bakke, Oddmund & Gregers, Tone Fredsvik (2012). Invariant chain as a tool to load antigenic peptides on MHC class I. Molecular Immunology. ISSN 0161-5890. 51(1), s. 16–16. doi: 10.1016/j.molimm.2012.02.039.
• Inderberg-Suso, Else M.; Wälchli, Sebastien; Myhre, Marit Renee; Yang, Weiwen; Trachsel, Sissel & Olweus, Johanna [Vis alle 9 forfattere av denne artikkelen] (2012). Targeting Microsatellite Instable Colon Cancer With Adoptively Transferred Redirected T cells. Journal of immunotherapy. ISSN 1524-9557. 35(9), s. 724–724.
• Taraldsrud, Eli; Floisand, Y; Aukrust, Pål; Rollag, Halvor; Fevang, Børre & Olweus, Johanna (2012). PLASMACYTOID DENDRITIC CELLS HAVE NORMAL FUNCTION IN PATIENTS WITH COMMON VARIABLE IMMUNODEFICIENCY. Journal of Clinical Immunology. ISSN 0271-9142. 32, s. 50–50.
• Kolstad, Arne; Kumari, Shraddha; Kvalheim, Gunnar; Bogsrud, Trond; Madsbu, Ulf Erik & Hagtvedt, Trond [Vis alle 10 forfattere av denne artikkelen] (2010). A Novel Cancer Vaccine Strategy In Previously Untreated Patients with Stage III/IV Follicular Lymphoma Generates Tumor-Reactive T Cells and Clinical Response. Blood. ISSN 0006-4971. 116(21), s. 753–754.
• Olsen, Dag Rune; Olweus, Johanna & Martinsen, Ørjan Grøttem (2009). Kvantemedisin - Mirakelmaskin eller bedrageri? [TV]. NRK Schrødingers katt.
• Kvale, Espen Østhagen; Fløisand, Yngvar; Lund-Johansen, Fridtjof; Rollag, Halvor; Brandtzæg, Per & Jahnsen, Frode Lars [Vis alle 7 forfattere av denne artikkelen] (2006). Plasmacytoid dendritic cells regulate recall responses by rapid induction of IL-10 in CD4+ memory T cells. Tissue Antigens. ISSN 0001-2815. 67, s. 443–444.
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