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Clinical Effectiveness Research

The research group is approaching different topics in clinical effectiveness of diagnostic  and therapeutic interventions. The group is responsible for several randomized trials related to colorectal cancer screening and gastrointestinal endoscopy. They are also conducting epidemiologic studies on mammography and studies concerning quality improvement of clinical practice.

The research group January 2018. Photo: Øystein H. Horgmo, UiO.

About the group

The group originates from an active research environment within the field of gastroenterology at Telemark Hospital in Norway. They have since the 1980's conducted research on screening for colorectal cancer. The group has been responsible for several randomized trials within endoscopic screening; theTelemark Polyp Study (TPS), the Norwegian Colorectal Cancer Prevention study (NORCCAP), and the Nordic-European Initiative on Colorectal Cancer (NordICC).

The Clinical Effectiveness Research Group was established at the University of Oslo in 2012. The group has the main responsibility for the multinational NordICC-trial and is strongly involved in the NORCCAP and TPS studies. In 2014 they initiated a large multinational study on surveillance after polypectomy; the European Polyp Surveillance (EPoS). In addition, they conduct research on clinical issues within gastroenterology, epidemiologic studies on mammography and quality improvement of clinical practice.


  • brettthauer_burda Shrunk the professor and sent him into patient's colon May 15, 2017 4:32 PM

    Professor Michael Bretthauer was the first gastroenterologist to be teleported into a patient's colon in a shrunked version of himself, only to get a better view of the colonic polyps. The sensational event took place during the Felix Burda Award in Berlin this weekend.

  • koloskop_600px Screening method not effective for older women Jan. 13, 2017 12:52 PM

    A paper published today in BMJ shows no effect of sigmoidoscopy screening in women aged 60 years and older. This new finding will have implications for a future Norwegian colorectal cancer screening program, where sigmoidoscopy is one of the recommended screening methods.


The group has received external funding from The Norwegian Research Council (NFR) and the South-Eastern Norway Regional Health Authority.


Together with collaborating research groups at Oslo University Hospital, they received grants from Stiftelsen K. G Jebsen in 2014, and formed the K. G Jebsen Colorectal Cancer Research Centre at Oslo University Hospital.

They have also formed the Regional Research Network for Clinical Effectiveness in Gastroenterology. This network has received funding from the South-Eastern Norway Regional Health Authority, and is a collaboration between researhers at Oslo University Hospital and the University of Oslo, Sørlandet Hospital in Arendal and Kristiansand, Telemark Hospital, Vestfold Hospital, Bærum Hospital Vestre Viken, Østfold Hospital and Innlandet Hospital.

The research group has a formal collaboration with several academic institutions abroad:

  • Harvard T.H Chan School of Public Health, Boston, USA
  • Karolinska Instituttet, Stockholm, Sweden
  • Erasmus Medical Centre, Rotterdam, Netherlands
  • Marie Curie Sklodowska Cancer Center, Warsawa, Poland
  • Sloan Kettering Memorial Cancer Center, New York City, USA
  • Uppsala University Hospital, Uppsala, Sweden
  • Landspitali University Hospital, Reykjavik, Iceland
Tags: Nordic, USA
Published Nov. 8, 2012 4:31 PM - Last modified Apr. 27, 2018 3:11 PM