Immunresponser ved revmatiske tilstander

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Gjennom detaljerte analyser av immuneceller i betent vev og blod ønsker vi å avdekke de underliggende mekanismene bak ulike revmatiske sykdommer, med spesielt fokus på leddbetennelse og revmatoid artritt. Med denne kunnskapen vil vi utvikle nye diagnostiske verktøy og identifisere terapeutiske mål.

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Synovial fluid cell isolation protocol affects immune cell recovery and composition across inflammatory states 23. okt. 2026 02:00
A human autoimmune organoid model reveals IL-7 function in coeliac disease 24. juli 2024 02:00
Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease 5. apr. 2024 02:00
Gluten-Free Diet Induces Rapid Changes in Phenotype and Survival Properties of Gluten-Specific T Cells in Celiac Disease 29. mars 2024 01:00
Identification of gluten T cell epitopes driving celiac disease 25. jan. 2023 01:00
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies 9. des. 2022 01:00
KIR+CD8+ T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19 8. mars 2022 01:00
Phenotype-Based Isolation of Antigen-Specific CD4+ T Cells in Autoimmunity: A Study of Celiac Disease 4. feb. 2022 01:00
Human KIR + CD8 + T cells target pathogenic T cells in Celiac disease and are active in autoimmune diseases and COVID-19 4. jan. 2022 01:00
Pathogenic T Cells in Celiac Disease Change Phenotype on Gluten Challenge: Implications for T-Cell-Directed Therapies 8. sep. 2021 02:00
Response to: "Some considerations about γδ and CD8+ T-cell responses in blood after gluten challenge in treated celiac disease" 10. juni 2021 02:00
Comprehensive Analysis of CDR3 Sequences in Gluten-Specific T-Cell Receptors Reveals a Dominant R-Motif and Several New Minor Motifs 30. apr. 2021 02:00
Circulating CD103+ γδ and CD8+ T cells are clonally shared with tissue-resident intraepithelial lymphocytes in celiac disease 3. mars 2021 01:00
Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease 9. feb. 2021 01:00
Peptide-MHC class I and class II tetramers: From flow to mass cytometry 1. jan. 2020 01:00
CD38 expression on gluten-specific T cells is a robust marker of gluten re-exposure in coeliac disease 17. des. 2019 01:00
Single-cell TCR sequencing of gut intraepithelial γδ T cells reveals a vast and diverse repertoire in celiac disease 16. nov. 2019 01:00
Therapeutic and Diagnostic Implications of T Cell Scarring in Celiac Disease and Beyond 24. juli 2019 02:00
Distinct phenotype of CD4+ T cells driving celiac disease identified in multiple autoimmune conditions 27. mars 2019 01:00
Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes 21. nov. 2018 01:00

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