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Norwegian PSC Research Center (NoPSC)

Primary sclerosing cholangitis (PSC) is a chronic inflammatory disorder of the bile ducts. Norwegian PSC Research Center was formally founded in 2008, but PSC research in Oslo dates back more than 30 years.

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Scientific and technical personnel at the Norwegian Center for PSC 2021

From the left: Trine Folseraas, Beate Vestad, Sajan Raju, Johannes, Hov, Mikal Hole, Henrik Rasmussen, Maria Maseng, Petra Hradicka, Kristian Holm, Merete Tysdahl, Espen Melum, Hanne Guldsten, Enya Amundsen-Isaksen, Peder Baadland, Mette Vesterhus, Markus Jördens, Guri Fossdal, Liv Wenche Thorbjørnsen, Anna Frank, Kari Otterdal, Tine Oldereid Kathrine Nordhus, Simen Hyll Hansen, Tom Hemming Karlsen, Kristin Kaasen Jørgensen, Erik Schrumpf, Marit Mæhle Grimsrud, Lise Katrine Engesæter and/og Xiaojun Jiang.

Photo: Private

Research Groups

The research at NoPSC is focused in three axis. Two of these axes are performed in the research groups of Espen Melum and Johannes Hov, and the third is being performed in tight collaboration between the research group of Trine Folseraas at UiO/OUH and Mette Vesterhus at Haraldsplass Deaconess Hospital in Bergen.


Experimental PSC Studies
The projects in the experimental group aim to understand the triggering and regulatory events taking place during cholangitis development.



Genomics and Metagenomics in Inflammatory Disorders
The projects in the genomics and metagenomics group aim to characterize and understand how alterations in the human genome and the gut microbial flora influence primary sclerosing cholangitis (PSC) susceptibility and cholangiocarcinoma development.


Clinical Studies
The main aim of the clinical studies in primary sclerosing cholangitis (PSC) is to determine effective means of treatment and diagnosis.


Core Facility

The NoPSC Biobank is a state-of-the-art biobank, where every sample is traceable throughout the system and both clinical parameters and biological materials are registered.

Published Oct. 25, 2011 3:22 PM - Last modified Oct. 12, 2022 2:10 PM


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