Geir Christensen

• Norden, Einar Sjaastad; Bendiksen, Bård Andre; Andresen, Henriette; Bergo, Kaja Knudsen; Espe, Emil Knut Stenersen; Hasic, Almira; Hauge-Iversen, Ida Marie; Veras, Ioanni; Hussain, Rizwan I.; Sjaastad, Ivar; Christensen, Geir Arve & Cataliotti, Alessandro (2021). Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload. ESC Heart Failure.  ISSN 2055-5822.  8(2), s 918- 927 . doi: 10.1002/ehf2.13177
• Alam, Jahedul; Musiime, Moses; Romaine, Andreas; Sawant, Mugdha; Melleby, Arne Olav; Lu, Ning; Eckes, Beate; Christensen, Geir Arve & Gullberg, Donald (2020). Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase. Matrix Biology Plus.  8 . doi: 10.1016/j.mbplus.2020.100045
• Berge, Kristian; Lyngbakken, Magnus; Myhre, Peder Langeland; Brynildsen, Jon; Røysland, Ragnhild; Strand, Heidi; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn & Røsjø, Helge (2020). High-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide in acute heart failure: Data from the ACE 2 study. Clinical Biochemistry.  ISSN 0009-9120.  s 1- 7 . doi: 10.1016/j.clinbiochem.2020.11.009 Fulltekst i vitenarkiv.
• Herum, Kate Louise Møller; Romaine, Andreas; Wang, Ariel; Melleby, Arne Olav; Strand, Mari Elen; Pacheco, Julian; Braathen, Bjørn; Dunér, Pontus; Tønnessen, Theis; Lunde, Ida Gjervold; Sjaastad, Ivar; Brakebusch, Cord; McCulloch, Andrew D.; Gomez, Maria F.; Carlson, Cathrine Rein & Christensen, Geir Arve (2020). Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin. Journal of the American Heart Association (JAHA).  ISSN 2047-9980.  9(3) . doi: 10.1161/JAHA.119.013518 Fulltekst i vitenarkiv.
• Mathiesen, Sabrina Bech; Lunde, Marianne; Stensland, Maria; Martinsen, Marita; Nyman, Tuula Anneli; Christensen, Geir Arve & Carlson, Cathrine Rein (2020). The cardiac syndecan-2 interactome. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X.  8:792, s 1- 18 . doi: 10.3389/fcell.2020.00792 Fulltekst i vitenarkiv.
• Mohammadzadeh, Naiyereh; Melleby, Arne Olav; Palmero, Sheryl; Sjaastad, Ivar; Chakravarti, Shukti; Engebretsen, Kristin V Thunheim; Christensen, Geir Arve; Lunde, Ida Gjervold & Tønnessen, Theis (2020). Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload. Cardiology.  ISSN 0008-6312.  145(3), s 187- 198 . doi: 10.1159/000505318
• Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Pisconti, Addolorata; Høst, Vibeke; Lunde, Marianne; Liland, Kristian Hovde; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2020). Syndecan-4–/– Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components.. Frontiers in Cell and Developmental Biology.  ISSN 2296-634X. . doi: 10.3389/fcell.2020.00730 Fulltekst i vitenarkiv. Vis sammendrag

  Background: Extracellular matrix (ECM) remodeling is essential for skeletal muscle development and adaption in response to environmental cues such as exercise and injury. The cell surface proteoglycan syndecan-4 has been reported to be essential for muscle differentiation, but few molecular mechanisms are known. Syndecan-4–/– mice are unable to regenerate damaged muscle, and display deficient satellite cell activation, proliferation, and differentiation. A reduced myofiber basal lamina has also been reported in syndecan-4–/– muscle, indicating possible defects in ECM production. To get a better understanding of the underlying molecular mechanisms, we have here investigated the effects of syndecan-4 genetic ablation on molecules involved in ECM remodeling and muscle growth, both under steady state conditions and in response to exercise. Methods: Tibialis anterior (TA) muscles from sedentary and exercised syndecan-4–/– and WT mice were analyzed by immunohistochemistry, real-time PCR and western blotting. Results: Compared to WT, we found that syndecan-4–/– mice had reduced body weight, reduced muscle weight, muscle fibers with a smaller cross-sectional area, and reduced expression of myogenic regulatory transcription factors. Sedentary syndecan-4–/– had also increased mRNA levels of syndecan-2, decorin, collagens, fibromodulin, biglycan, and LOX. Some of these latter ECM components were reduced at protein level, suggesting them to be more susceptible to degradation or less efficiently translated when syndecan-4 is absent. At the protein level, TRPC7 was reduced, whereas activation of the Akt/mTOR/S6K1 and Notch/HES-1 pathways were increased. Finally, although exercise induced upregulation of several of these components in WT, a further upregulation of these molecules was not observed in exercised syndecan-4–/– mice. Conclusion: Altogether our data suggest an important role of syndecan-4 in muscle development.

• Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Eken, Olav Søvik; Sadredini, Mani; Myhre, Peder Langeland; Shen, Xin; Dalhus, Bjørn; Laver, Derek R.; Lunde, Per Kristian; Kurola, Jouni; Lunde, Marianne; Hoff, Jon Erik; Godang, Kristin; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Lehnart, Stephan E.; Edwards, Andrew; Lunde, Ida Gjervold; Omland, Torbjørn; Stokke, Mathis Korseberg; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2019). Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia. Circulation: Arrhythmia and Electrophysiology.  ISSN 1941-3149.  12(4) . doi: 10.1161/CIRCEP.118.007045 Fulltekst i vitenarkiv.
• Brynildsen, Jon; Myhre, Peder Langeland; Lyngbakken, Magnus; Klæboe, Lars Gunnar; Stridsberg, Mats; Christensen, Geir Arve; Edvardsen, Thor; Omland, Torbjørn & Røsjø, Helge (2019). Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis. Clinical Biochemistry.  ISSN 0009-9120.  71, s 17- 23 . doi: 10.1016/j.clinbiochem.2019.06.008 Fulltekst i vitenarkiv.
• Brynildsen, Jon; Petaja, Liisa; Myhre, Peder Langeland; Lyngbakken, Magnus; Nygård, Ståle; Stridsberg, Mats; Christensen, Geir Arve; Ottesen, Anett Hellebø; Pettilä, Ville; Omland, Torbjørn & Røsjø, Helge (2019). Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study. Critical Care Medicine.  ISSN 0090-3493.  47(5), s e412- e419 . doi: 10.1097/CCM.0000000000003670
• Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Buonarati, Olivia R.; Cataliotti, Alessandro; Hell, Johannes W.; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2019). Cardiomyocyte substructure reverts to an immature phenotype during heart failure. Journal of Physiology.  ISSN 0022-3751.  597(7), s 1833- 1853 . doi: 10.1113/JP277273 Fulltekst i vitenarkiv.
• Mathiesen, Sabrina Bech; Lunde, Marianne; Aronsen, Jan Magnus; Romaine, Andreas; Kaupang, Anita; Martinsen, Marita; De Souza, Gustavo Antonio; Nyman, Tuula Anneli; Sjaastad, Ivar; Christensen, Geir Arve & Carlson, Cathrine Rein (2019). The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP). Journal of Biological Chemistry.  ISSN 0021-9258.  294(22), s 8717- 8731 . doi: 10.1074/jbc.RA118.006423 Fulltekst i vitenarkiv. Vis sammendrag

  Costameres are signaling hubs at the sarcolemma and important contact points between the extracellular matrix and cell interior, sensing and transducing biomechanical signals into a cellular response. The transmembrane proteoglycan syndecan-4 localizes to these attachment points and has been shown to be important in the initial stages of cardiac remodeling, but its mechanistic function in the heart remains insufficiently understood. Here, we sought to map the cardiac interactome of syndecan-4 to better understand its function and downstream signaling mechanisms. By combining two different affinity purification methods with MS analysis, we found that the cardiac syndecan-4 interactome consists of 21 novel and 29 previously described interaction partners. Nine of the novel partners were further validated to bind syndecan-4 in HEK293 cells (i.e. CAVIN1/PTRF, CCT5, CDK9, EIF2S1, EIF4B, MPP7, PARVB, PFKM, and RASIP). We also found that 19 of the 50 interactome partners bind differently to syndecan-4 in the left ventricle lysate from aortic-banded heart failure (ABHF) rats compared with SHAM-operated animals. One of these partners was the well-known mechanotransducer muscle LIM protein (MLP), which showed direct and increased binding to syndecan-4 in ABHF. Nuclear translocation is important in MLP-mediated signaling, and we found less MLP in the nuclear-enriched fractions from syndecan-4-/- mouse left ventricles but increased nuclear MLP when syndecan-4 was overexpressed in a cardiomyocyte cell line. In the presence of a cell-permeable syndecan-4-MLP disruptor peptide, the nuclear MLP level was reduced. These findings suggest that syndecan-4 mediates nuclear translocation of MLP in the heart

• Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Andenæs, Kine; Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Marstein, Henriette; Bandlien, Caroline; Nygård, Ståle; Gorham, Joshua; Sjaastad, Ivar; Chakravarti, Shukti; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2019). The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload. Scientific Reports.  ISSN 2045-2322.  9:9206, s 1- 13 . doi: 10.1038/s41598-019-45651-9 Fulltekst i vitenarkiv.
• Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Manfra, Ornella; Longobardi, S; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Husebye, T.; Kolstad, Terje R Selnes; Cataliotti, Alessandro; Christensen, Geir Arve; Sejersted, Ole M; Niederer, Steven A.; Andersen, Geir Øystein; Sjaastad, Ivar & Louch, William Edward (2019). Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression. Cardiovascular Research (CVR).  ISSN 0008-6363.  115(4), s 752- 764 . doi: 10.1093/cvr/cvy257
• Udjus, Camilla; Fadila, Cero; Halvorsen, Bente; Behmen, Dina; Carlson, Cathrine Rein; Bendiksen, Bård Andre; Espe, Emil Knut Stenersen; Sjaastad, Ivar; Løberg, Else Marit; Yndestad, Arne; Aukrust, Pål; Christensen, Geir Arve; Skjønsberg, Ole Henning & Larsen, Karl-Otto (2019). Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  316(6), s L999- L1012 . doi: 10.1152/ajplung.00322.2018 Fulltekst i vitenarkiv.
• Andenæs, Kine; Lunde, Ida Gjervold; Mohammadzadeh, Naiyereh; Dahl, Christen Peder; Aronsen, Jan Magnus; Strand, Mari Elen; Palmero, Sheryl; Sjaastad, Ivar; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2018). The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling. PLOS ONE.  ISSN 1932-6203.  13(7), s 1- 20 . doi: 10.1371/journal.pone.0201422 Fulltekst i vitenarkiv.
• Berge, Kristian Collin; Lyngbakken, Magnus; Einvik, Gunnar; Winther, Jacob Andreas; Brynildsen, Jon; Røysland, Ragnhild; Strand, Heidi; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn & Røsjø, Helge (2018). Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study. Clinical Biochemistry.  ISSN 0009-9120.  59, s 62- 68 . doi: 10.1016/j.clinbiochem.2018.07.006
• Christensen, Geir Arve; Herum, Kate Louise Møller & Lunde, Ida Gjervold (2018). Sweet, yet underappreciated: Proteoglycans and extracellular Matrix remodeling in heart disease. Matrix Biology.  ISSN 0945-053X.  75-76, s 286- 299 . doi: 10.1016/j.matbio.2018.01.001
• Lyngbakken, Magnus Nakrem; Pervez, Mohammad Osman; Brynildsen, Jon; Pedersen, Marit Holmefjord; Sølvernes, Janne; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn & Røsjø, Helge (2018). Fibroblast growth factor 23 in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. Clinical Biochemistry.  ISSN 0009-9120.  52, s 41- 47 . doi: 10.1016/j.clinbiochem.2017.10.015 Fulltekst i vitenarkiv.
• Melleby, Arne Olav; Romaine, Andreas; Aronsen, Jan Magnus; Veras, Ioanni; Zhang, Lili; Sjaastad, Ivar; Lunde, Ida Gjervold & Christensen, Geir Arve (2018). A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice. Cardiovascular Research (CVR).  ISSN 0008-6363. . doi: 10.1093/cvr/cvy141 Fulltekst i vitenarkiv.
• Pervez, Mohammad Osman; Winther, Jacob Andreas; Brynildsen, Jon; Strand, Heidi; Christensen, Geir Arve; Høiseth, Arne Didrik; Myhre, Peder Langeland; Røysland, Ragnhild; Lyngbakken, Magnus; Omland, Torbjørn & Røsjø, Helge (2018). Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study. Biomarkers.  ISSN 1354-750X.  s 1- 11 . doi: 10.1080/1354750X.2018.1474258
• Røsjø, Helge; Masson, Serge; Caironi, Pietro; Stridsberg, Mats; Magnoli, Michela; Christensen, Geir Arve; Moise, Gabriella; Urbano, Maria Cristina; Gattinoni, Luciano; Pesenti, Antonio; Latini, Roberto & Omland, Torbjørn (2018). Prognostic value of secretoneurin in patients with severe sepsis and septic shock: Data from the albumin Italian outcome sepsis study. Critical Care Medicine.  ISSN 0090-3493.  46(5), s e404- e410 . doi: 10.1097/CCM.0000000000003050 Fulltekst i vitenarkiv.
• Yaddehi Gamage, Thilini Hansamali Gamage; Gunnes, Gjermund; Lee, Robert Hugh; Louch, William Edward; Holmgren, Asbjørn; Bruton, Joseph D.; Lengle, Emma; Kolstad, Terje R Selnes; Revold, Tobias; Amundsen, Silja Svanstrøm; Dalen, Knut Tomas; Holme, Pål Andre; Tjønnfjord, Geir Erland; Christensen, Geir Arve; Westerblad, Håkan; Klungland, Arne; Bergmeier, Wolfgang; Misceo, Doriana & Frengen, Eirik (2018). STIM1 R304W causes muscle degeneration and impaired platelet activation in mice. Cell Calcium.  ISSN 0143-4160.  76, s 87- 100 . doi: 10.1016/j.ceca.2018.10.001 Fulltekst i vitenarkiv. Vis sammendrag

  STIM1 and ORAI1 regulate store-operated Ca2+ entry (SOCE) in most cell types, and mutations in these proteins have deleterious and diverse effects. We established a mouse line expressing the STIM1 R304 W gain-of-function mutation causing Stormorken syndrome to explore effects on organ and cell physiology. While STIM1 R304 W was lethal in the homozygous state, surviving mice presented with reduced growth, skeletal muscle degeneration, and reduced exercise endurance. Variable STIM1 expression levels between tissues directly impacted cellular SOCE capacity. In contrast to patients with Stormorken syndrome, STIM1 was downregulated in fibroblasts from Stim1R304W/R304W mice, which maintained SOCE despite constitutive protein activity. In studies using foetal liver chimeras, STIM1 protein was undetectable in homozygous megakaryocytes and platelets, resulting in impaired platelet activation and absent SOCE. These data indicate that downregulation of STIM1 R304 W effectively opposes the gain-of-function phenotype associated with this mutation, and highlight the importance of STIM1 in skeletal muscle development and integrity.

• Abraityte, Judita Aurelija; Lunde, Ida Gjervold; Askevold, Erik Tandberg; Michelsen, Annika; Christensen, Geir Arve; Aukrust, Pål; Yndestad, Arne; Fiane, Arnt E; Andreassen, Arne K.; Aakhus, Svend; Dahl, Christen Peder; Gullestad, Lars; Broch, Kaspar & Ueland, Thor (2017). Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy. Scientific Reports.  ISSN 2045-2322.  7(1) . doi: 10.1038/s41598-017-03625-9 Fulltekst i vitenarkiv.
• Abraityte, Judita Aurelija; Vinge, Leif Erik; Askevold, Erik Tandberg; Lekva, Tove; Michelsen, Annika; Ranheim, Trine; Alfsnes, Katrine; Fiane, Arnt E; Aakhus, Svend; Lunde, Ida Gjervold; Dahl, Christen Peder; Aukrust, Pål; Christensen, Geir Arve; Gullestad, Lars; Yndestad, Arne & Ueland, Thor (2017). Wnt5a is elevated in heart failure and affects cardiac fibroblast function. Journal of Molecular Medicine.  ISSN 0946-2716.  95(7), s 767- 777 . doi: 10.1007/s00109-017-1529-1
• Dhondup, Yangchen; Sjaastad, Ivar; Sandanger, Øystein; Aronsen, Jan Magnus; Ahmed, Muhammad Shakil; Attramadal, Håvard; Finsen, Alexandra; Zhang, Lili; Ranheim, Trine; Alfsnes, Katrine; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2017). Toll-like receptor 9 promotes survival in SERCA2a KO heart failure mice. Mediators of Inflammation.  ISSN 0962-9351.  2017:9450439, s 1- 11 . doi: 10.1155/2017/9450439 Fulltekst i vitenarkiv.
• Herum, Kate Louise Møller; Lunde, Ida Gjervold; McCulloch, Andrew D. & Christensen, Geir Arve (2017). The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart. Journal of Clinical Medicine.  ISSN 2077-0383.  6(53) . doi: 10.3390/jcm6050053 Fulltekst i vitenarkiv.
• Myhre, Peder Langeland; Stridsberg, Mats; Linko, Rita; Okkonen, Marjatta; Nygård, Ståle; Christensen, Geir Arve; Pettilä, Ville; Omland, Torbjørn & Røsjø, Helge (2017). Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study. Biomarkers.  ISSN 1354-750X.  22(8), s 775- 781 . doi: 10.1080/1354750X.2016.1269200 Fulltekst i vitenarkiv.
• Norum, Hilde Margrethe; Broch, Kaspar; Michelsen, Annika; Lunde, Ida Gjervold; Lekva, Tove; Abraityte, Judita Aurelija; Dahl, Christen Peder; Fiane, Arnt E; Andreassen, Arne K.; Christensen, Geir Arve; Aakhus, Svend; Aukrust, Pål; Gullestad, Lars & Ueland, Thor (2017). The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy. Journal of Cardiovascular Translational Research.  ISSN 1937-5387.  s 1- 10 . doi: 10.1007/s12265-017-9748-y
• Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine; Palibrk, Vuk; Wang, Junbai; Neurauter, Christine Gran; Gomez, Luisa Fernanda Luna; Johansen, Jostein; Øgaard, Jonas; Ohm, Ingrid Kristine; Slupphaug, Geir; Kusnierczyk, Anna; Fiane, Arnt E; Brorson, Sverre Henning; Zhang, Lili; Gullestad, Lars; Louch, William Edward; Iversen, Per Ole; Østlie, Ingunn; Klungland, Arne; Christensen, Geir Arve; Sjaastad, Ivar; Sætrom, Pål; Yndestad, Arne; Aukrust, Pål; Bjørås, Magnar & Finsen, Alexandra (2017). NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports.  ISSN 2211-1247.  18, s 82- 92 . doi: 10.1016/j.celrep.2016.12.009 Fulltekst i vitenarkiv.
• Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune Forstrøm; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Sjaastad, Ivar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2017). Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis. Circulation: Heart Failure.  ISSN 1941-3289.  10(2) . doi: 10.1161/CIRCHEARTFAILURE.116.003675
• Ottesen, Anett Hellebø; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2017). Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure. Current Heart Failure Reports.  ISSN 1546-9530.  14 . doi: 10.1007/s11897-017-0360-x Fulltekst i vitenarkiv.
• Pervez, Mohammad Osman; Lyngbakken, Magnus Nakrem; Myhre, Peder Langeland; Brynildsen, Jon; Langsjøen, Eva Camilla; Høiseth, Arne Didrik; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2017). Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. Clinical Biochemistry.  ISSN 0009-9120.  50(7-8), s 394- 400 . doi: 10.1016/j.clinbiochem.2016.12.010 Fulltekst i vitenarkiv.
• Romaine, Andreas; Sørensen, Ida Wiig; Zeltz, Cedric; Lu, Ning; Erusappan, Pugazendhi Murugan; Melleby, Arne Olav; Zhang, Lili; Bendiksen, Bård Andre; Robinson, EL; Aronsen, Jan Magnus; Herum, Kate Louise Møller; Danielsen, Håvard Emil; Sjaastad, Ivar; Christensen, Geir Arve & Gullberg, Donald (2017). Overexpression of integrin α11 induces cardiac fibrosis in mice. Acta Physiologica Scandinavica.  ISSN 0001-6772.  222:e13025(2), s 1- 17 . doi: 10.1111/apha.12932
• Winther, Jacob Andreas; Brynildsen, Jon; Høiseth, Arne Didrik; Strand, Heidi; Følling, Ivar; Christensen, Geir Arve; Nygård, Ståle; Røsjø, Helge & Omland, Torbjørn (2017). Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: Data from the ACE 2 study. Respiratory Research.  ISSN 1465-9921.  18(184) . doi: 10.1186/s12931-017-0665-z Fulltekst i vitenarkiv.
• Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Sejersted, Ole M; Christensen, Geir Arve; Sjaastad, Ivar & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research (CVR).  ISSN 0008-6363. . doi: 10.1093/cw111
• Høiseth, Arne Didrik; Brynildsen, Jon; Hagve, Tor-Arne; Christensen, Geir Arve; Søyseth, Vidar; Omland, Torbjørn & Røsjø, Helge (2016). The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: Data from the Akershus cardiac examination (ACE) 2 study. Biomarkers.  ISSN 1354-750X.  21(2), s 173- 179 . doi: 10.3109/1354750X.2015.1126645
• Lunde, Ida Gjervold; Herum, Kate Louise Møller; Carlson, Cathrine Rein & Christensen, Geir Arve (2016). Syndecans in heart fibrosis. Cell and Tissue Research.  ISSN 0302-766X.  365(3), s 539- 552 . doi: 10.1007/s00441-016-2454-2
• Melleby, Arne Olav; Strand, Mari Elen; Romaine, Andreas; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Arnt E; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparan sulfate proteoglycan glypican-6 is upregulated in the failing heart, and regulates cardiomyocyte growth through ERK1/2 Signaling. PLOS ONE.  ISSN 1932-6203.  11(10) . doi: 10.1371/journal.pone.0165079
• Myhre, Peder Langeland; Ottesen, Anett Hellebø; Okkonen, Marjatta; Linko, Rita; Stridsberg, Mats; Nygård, Ståle; Christensen, Geir Arve; Pettilä, Ville; Omland, Torbjørn & Røsjø, Helge (2016). Prognostic value of secretoneurin in patients with acute respiratory failure:Data from the FINNALI study. Clinical Chemistry.  ISSN 0009-9147.  62(10), s 1380- 1389 . doi: 10.1373/clinchem.2016.258764
• Røsjø, Helge; Stridsberg, Mats; Ottesen, Anett Hellebø; Nygård, Ståle; Christensen, Geir Arve; Pettilä, Ville; Linko, Rita; Karlsson, Sari; Varpula, Tero; Ruokonen, Esko & Omland, Torbjørn (2016). Prognostic Value of Secretoneurin in Critically Ill Patients with Infections. Critical Care Medicine.  ISSN 0090-3493.  44(10), s 1882- 1890 . doi: 10.1097/CCM.0000000000001832
• Winther, Jacob Andreas; Brynildsen, Jon; Høiseth, Arne Didrik; Følling, Ivar; Brekke, Pål Haugar; Christensen, Geir Arve; Hagve, Tor-Arne; Verbalis, Joseph G.; Omland, Torbjørn & Røsjø, Helge (2016). Prevalence and prognostic significance of hyponatremia in patients with acute exacerbation of chronic obstructive pulmonary disease: Data from the akershus cardiac examination (ACE) 2 study. PLOS ONE.  ISSN 1932-6203.  11:e0161232(8) . doi: 10.1371/journal.pone.0161232 Fulltekst i vitenarkiv.
• Brynildsen, Jon; Høiseth, Arne Didrik; Nygård, Ståle; Hagve, Tor-Arne; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2015). Diagnostisk treffsikkerhet for hjertesvikt – data fra Akershus hjerteundersøkelse 2. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  135(19), s 1738- 1744 . doi: 10.4045/tidsskr.14.1174
• Dhondup, Yangchen; Sjaastad, Ivar; Scott, Helge; Sandanger, Øystein; Zhang, Lili; Haugstad, Solveig Bjærum; Aronsen, Jan Magnus; Ranheim, Trine; Holmen, Sigve; Alfsnes, Katrine; Ahmed, Muhammad Shakil; Attramadal, Håvard; Gullestad, Lars; Aukrust, Pål; Christensen, Geir Arve; Yndestad, Arne & Vinge, Leif Erik (2015). Sustained toll-like receptor 9 activation promotes systemic and cardiac inflammation, and aggravates diastolic heart failure in SERCA2a KO Mice. PLOS ONE.  ISSN 1932-6203.  10:e0139715(10) . doi: 10.1371/journal.pone.0139715 Fulltekst i vitenarkiv.
• Einvik, Gunnar; Dammen, Toril; Høiseth, Arne Didrik; Brynildsen, Jon; Hagve, Tor-Arne; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2015). Psychological distress and mortality in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. General Hospital Psychiatry.  ISSN 0163-8343.  37(6), s 548- 553 . doi: 10.1016/j.genhosppsych.2015.07.007
• Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Ranheim, Trine; Lunde, Ida Gjervold; Olsen, Maria Belland; Lien, Egil; Zhang, Lili; Haugstad, Solveig Bjærum; Løberg, Else Marit; Christensen, Geir Arve; Larsen, Karl-Otto & Skjønsberg, Ole Henning (2015). Absence of the inflammasome adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  309(4), s L378- L387 . doi: 10.1152/ajplung.00342.2014
• Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Ranheim, Trine; Lunde, Ida Gjervold; Olsen, Maria Belland; Lien, Egil; Zhang, Lili; Haugstad, Solveig Bjærum; Løberg, Else Marit; Christensen, Geir Arve; Larsen, Karl-Otto & Skjønsberg, Ole Henning (2015). Absence of the inflammasone adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology.  ISSN 1040-0605.  309, s L378- L387 . doi: 10.1152/ajplung.00342.2014
• Herum, Kate Louise Møller; Lunde, Ida Gjervold; Skrbic, Biljana; Louch, William Edward; Hasic, Almira; Boye, Sigurd; Unger, Andreas; Brorson, Sverre Henning; Sjaastad, Ivar; Tønnessen, Theis; Linke, Wolfgang A.; Gomez, Maria F. & Christensen, Geir Arve (2015). Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart. Cardiovascular Research (CVR).  ISSN 0008-6363.  106, s 217- 226 . doi: 10.1093/cvr/cvv002
• Hillestad, Vigdis; Espe, Emil Knut Stenersen; Fadila, Cero; Larsen, Karl-Otto; Sjaastad, Ivar; Nygård, Ståle; Skjønsberg, Ole Henning & Christensen, Geir Arve (2015). IL-18 neutralization during alveolar hypoxia improves left ventricular diastolic function in mice. Acta Physiologica.  ISSN 1748-1708.  213(2), s 492- 504 . doi: 10.1111/apha.12376
• Kho, Changwon; Lee, Ahyoung; Jeong, Dongtak; Oh, Jae Gyun; Gorski, Przemek A.; Fish, Kenneth; Sanchez, Roberto; DeVita, Robert J; Christensen, Geir Arve; Dahl, Russell & Hajjar, Roger J. (2015). Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure. Nature Communications.  ISSN 2041-1723.  6:7229 . doi: 10.1038/ncomms8229
• Majak, Piotr; Lunde, Ida Gjervold; Hasic, Almira; Husebye, Trygve Guttorm; Christensen, Geir Arve; Tønnessen, Theis & BJØRNSTAD, JOHANNES (2015). Reduced visfatin levels in aortic stenosis increase after aortic valve replacement and may contribute to reverse left ventricular remodelling. Journal of Cardiovascular Surgery.  ISSN 0021-9509.  56(3), s 483- 492
• Ottesen, Anett Hellebø; Louch, William Edward; Carlson, Cathrine Rein; Landsverk, Ole J. B.; Kurola, Jouni; Johansen, Rune Forstrøm; Moe, Morten Kaare; Aronsen, Jan Magnus; Høiseth, Arne Didrik; Jarstadmarken, Hilde; Nygård, Ståle; Bjørås, Magnar; Sjaastad, Ivar; Pettilä, Ville; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling. Journal of the American College of Cardiology.  ISSN 0735-1097.  65(4), s 339- 351 . doi: 10.1016/j.jacc.2014.10.065

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• Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Pisconti, Addolorate; Lunde, Marianne; Liland, Kristian Hovde; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2019). Extracellular Matrix remodeling and multiple signaling pathways are regulated by syndecan-4 during myogenesis.
• Udjus, Camilla; Cero, Fadila; Halvorsen, Bente; Aukrust, Pål; Christensen, Geir Arve; Skjønsberg, Ole Henning & Larsen, Karl-Otto (2018). Inhibition of caspase-1 reduces hypoxia-induced pulmonary hypertension by downregulating smooth muscle cell growth.
• Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Laver, Derek R; Myhre, Peder Langeland; Dalhus, Bjørn; Lunde, Per Kristian; Lunde, Marianne; Hoff, Jon Erik; Godang, Kristin; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2017). Secretoneurin is an Endogenous CaMKII Inhibitor That Attenuates Ca2+-Dependent Arrhythmogenesis. Circulation.  ISSN 0009-7322.  136, s A13900
• Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Liland, Kristian Hovde; Stang, Espen; Sjaastad, Ivar; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2017). Syndecan-4 is a skeletal muscle regenerator and is important for normal skeletal muscle fibre development..
• Aronsen, Jan Magnus; Singbrant, Sofie; Christensen, Geir Arve & Iversen, Per Ole (2016). Evidence for splenic stress-induced erythropoiesis in mice with post-infarction heart failure.
• Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar; Christensen, Geir Arve & Louch, William Edward (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
• Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2016). BIN1 triggers t-tubule development in cardiomyocytes.
• Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Conner, David; Benson, Craig; DePalma, Steve; Christensen, Geir Arve; Linke, Wolfgang A.; Seidman, Jonathan G. & Seidman, Christine E. (2016). Study of a mouse with proximal titin A-band truncation reveals disease mechanisms and modifiers of titin dilated cardiomyopathy.
• Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Conner, David; Gorham, Joshua; DePalma, Steve; Christensen, Geir Arve; Linke, Wolfgang A.; Seidman, Jonathan G. & Seidman, Christine E. (2016). Titin A-band truncation mutation in mice causes stress-induced dilated cardiomyopathy.
• Mathiesen, Sabrina Bech; Lunde, Marianne; Christensen, Geir Arve & Carlson, Cathrine Rein (2016). Mass spectrometry analysis of cytoplasmic binding partners of cardiac syndecan - 2.
• Mathiesen, Sabrina Bech; Lunde, Marianne; Christensen, Geir Arve & Carlson, Cathrine Rein (2016). Mass spectrometry analysis of cytoplasmic binding partners of cardiac syndecan-2.
• Melleby, Arne Olav; Strand, Mari Elen; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Andrew; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). Glypican-6 is upregulated in heart failure and mediates cardiomyocyte growth through ERK1/2 signaling.
• Mohammadzadeh, Naiyereh; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to cardiac dysfunction in response to pressure overload.
• Mohammadzadeh, Naiyereh; Engebretsen, Kristin; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen; Marstein, Henriette; Aronsen, Jan Magnus; Nygård, Ståle; Skrbic, Biljana; Bandlien, Caroline; Andenæs, Kine; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2016). Lack of the extracellular matrix proteoglycan lumican leads to ventricular dilatation, attenuated hypertrophy and contractile dysfunction in response to pressure overload.
• Romaine, Andreas; Sørensen, Ida Wiig; Melleby, Arne Olav; Zeltz, Cedric; Zhang, Lili; Bendiksen, Bård Andre; Lu, Neha; Herum, Kate Louise Møller; Danielsen, D.; Sjaastad, Ivar; Gullberg, Donald & Christensen, Geir Arve (2016). Overexpression of integrin a11 induces cardiac hypertrophy and fibrosis.
• Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five; Aakhus, Svend; Lunde, Ida Gjervold; Almaas, Vibeke; Gullestad, Lars; Sjaastad, Ivar; Tønnessen, Theis; Sejersted, Ole M; Norseng, Per Andreas; Christensen, Geir Arve & Louch, William Edward (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
• Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
• Rønning, Sissel Beate; Carlson, Cathrine Rein; Høst, Vibeke; Aronsen, Jan Magnus; Liland, Kristian Hovde; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve & Pedersen, Mona Elisabeth (2016). Syndecan-4 is important for normal skeletal muscle fibre development.
• Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazaukaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
• Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazauskaite, Monika; Sjaastad, Ivar; Christensen, Geir Arve & Lunde, Ida Gjervold (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
• Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Edwards, Andrew; Landsverk, Ole J. B.; Johansen, Rune Forstrøm; Moe, Morten Kaare; Bjørås, Magnar; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin,a novel endogenous CaMKII inhibitor, augments cardiomyocyte Calcium handling and inhibits arrhythmogenic Calcium release. Biophysical Journal.  ISSN 0006-3495.  108, s 340a- 340a
• Andenæs, Kine; Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Strand, Mari Elen; Marstein, Henriette; Dahl, Christen Peder; Sjaastad, Ivar; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim & Tønnessen, Theis (2015). The extracellular matrix proteoglycan fibromodulin is up-regulated in experimental and clinical heart failure, and might be involved in regulation of myocardial fibrosis by interacting with TGF-B.
• Carlson, Cathrine Rein; Nygård, Ståle; Sirnes, Solveig; Jarstadmarken, Hilde; Martinsen, Marita; Lunde, Marianne; Tutturen, Astrid Elisabeth Voorham; De Souza, Gustavo Antonio & Christensen, Geir Arve (2015). A protein-protein interaction (PPI) map of cardiac syndecan-4.
• Cero, Fadila; Larsen, Karl-Otto; Hillestad, Vigdis; Olsen, Maria Belland; Udjus, Camilla; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål; Løberg, Else Marit; Christensen, Geir Arve & Skjønsberg, Ole Henning (2015). The inflammasome adaptor ASC mediates pulmonary artery remodelling.
• Cero, Fadila; Larsen, Karl-Otto; Hillestad, Vigdis; Olsen, Maria Belland; Udjus, Camilla; Yndestad, Arne; Aukrust, Pål; Løberg, Else Marit; Christensen, Geir Arve & Skjønsberg, Ole Henning (2015). Hypoxic pulmonary hypertension; a role for the inflammasome.
• Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Lunde, Ida Gjervold; Jølle, Guro Five; Almaas, Victor; Gullestad, Lars; Christensen, Geir Arve; Aakhus, Svend; Sejersted, Ole M; Tønnessen, Theis; Sjaastad, Ivar & Louch, William Edward (2015). Maintained cardiomyocyte t-tubule structure and function in patients with non-dilated hypertrophy.
• Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu; Zhang, Lili; Norseng, Per Andreas; Christensen, Geir Arve; Sejersted, Ole M; Sjaastad, Ivar & Louch, William Edward (2015). Ventricular wall stress predicts disruption of cardiomyocyte t-tubule structure and Ca2+ homeostasis across the infarcted heart. Biophysical Journal.  ISSN 0006-3495.  108, s 106a
• Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
• Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
• Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, John Andrew; Christensen, Geir Arve & Louch, William Edward (2015). BIN1 regulates t-tubule growth during cardiac development and diseases.
• Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sejersted, Ole M; Sjaastad, Ivar; Wasserstrom, J. Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (BIN1) initiates t-tubule Growth during Cardiac Development and disease. Biophysical Journal.  ISSN 0006-3495.  108, s 130a- 130a
• Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William; Sjaastad, Ivar; Wasserstrom, Andrew; Christensen, Geir Arve & Louch, William Edward (2015). Bridging integrator 1 (B1N1) initiates t-tubule growth cardiac development and disease.
• Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Soukoulis, Victor; Linke, Wolfgang A.; Gorham, joshua; Conner, David; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2015). Proximal titin A-band truncation causes dilated cardiomyopathy in response to increased afterload in mice.
• Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Soukoulis, Victor; Linke, Wolfgang E.; Gorham, Joshua; Conner, David; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2015). Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy.
• Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Gorham, joshua; Conner, David; Christensen, Geir Arve; Linke, Wolfgang A.; Seidman, Jonathan G. & Seidman, Christine E. (2015). 7th Joint Scandinavian Conference in Cardiothoracic Surgery.
• Lunde, Ida Gjervold; Wakimoto, Hiroko; Jianming, Jiang; Burke, Michael A.; Soukoulis, Victor; Unger, Andreas; Conner, David; Gorham, Joshua; DePalma, Steve; Christensen, Geir Arve; Seidman, Jonathan G. & Seidman, Christine E. (2015). Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy.
• Melleby, Arne Olav; Strand, Mari Elen; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder; Sjaastad, Ivar; Fiane, Arnt E; Filmus, Jorge; Christensen, Geir Arve & Lunde, Ida Gjervold (2015). Glypican-6 is increased in experimental and clinical heart failure and might play a role in cardiac fibrosis through BMP4 signalling.
• Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Marstein, Henriette; Aronsen, Jan Magnus; Skrbic, Biljana; Bandlien, Caroline; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2015). The role of lumican in Cardiac pressure overload.
• Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V.; Lunde, Ida Gjervold; Sjaastad, Ivar; Marstein, Henriette; Aronsen, Jan Magnus; Skrbic, Biljana; Bandlien, Caroline; Chakravarti, Shukti; Christensen, Geir Arve & Tønnessen, Theis (2015). The role of lumican in Cardiac pressure overload.
• Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland; Johansen, Rune F.; Jarstadmarken, Hilde; Bjørås, Magnar; Sjaastad, Ivar; Høiseth, Arne Didrik; Brynildsen, Jon; Stridsberg, Mats; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Enhanced myocardial chromogranin A glycosylation in acute heart failure: reduced processing and potential impact on cardiomyocyte calcium homeostasis.
• Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Johansen, Rune F.; Stridsberg, Mats; Jarstadmarken, Hilde; Bjørås, Magnar; Høiseth, Arne Didrik; Brynildsen, Jon; Omland, Torbjørn; Christensen, Geir Arve & Røsjø, Helge (2015). Chromogranin A is a potent prognostic biomarker in acute heart failure, and its fragment catestatin regulates cardiomyocyte calcium homeostasis by CaMKII inhibition.
• Ottesen, Anett Hellebø; Laver, Derek; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin a novel endogenous CaMKIIð inhibitor, inhibits Ca2+ dependent arrhythmogenesis.
• Romaine, Andreas; Herum, Kate Louise Møller; Sørensen, Ida Wiig; Hasic, Almira; Sjaastad, Ivar; Gullberg, Donald & Christensen, Geir Arve (2015). Syndecan-4 regulates profibrotic a11B1 integrin expression in the pressure-overloaded heart.
• Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca 2+ homeostasis.
• Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
• Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
• Ruud, Marianne; Frisk, Michael; Norseng, Per Andreas; Røe, Åsmund Treu; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Sjaastad, Ivar; Sejersted, Ole M; Christensen, Geir Arve & Louch, William Edward (2015). Regulation of cardiomyocyte t-tubule organization and density by ventricular wall stress. Biophysical Journal.  ISSN 0006-3495.  108, s 443a- 443a
• Rønning, Sissel Beate; Carlson, C. R.; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve; Hollung, Kristin & Pedersen, Mona Elisabeth (2015). Syndecan-4 in skeletal muscle development and regeneration.

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