Geir Christensen

Professor II - Institutt for eksperimentell medisinsk forskning

English version of this page

E-post geir.christensen@medisin.uio.no

Brukernavn

Besøksadresse Kirkeveien 166 Bygg 7 0450 Oslo

Postadresse Postboks 4956 Nydalen OUS HF Ullevål sykehus 0424 Oslo

Last ned visittkort

Faglige interesser

Forskning på hjertesvikt

Undervisning

Leder for Norwegian PhD School of Heart Research

Bakgrunn

Medisinsk embetseksamen (cand. med.) 1980

Autorisasjon som lege 1982

Medisinsk doktorgrad (dr. med.) ved Universitetet i Oslo 1993

Mastergrad i helseadministrasjon, Senter for helseadministrasjon, Universitetet i Oslo 2004

Priser

Nasjonalforeningens hjertepris 2011

http://www.kongehuset.no/c26939/nyhet/vis.html?tid=89563

Verv

Leder for Senter for hjertesviktforskning

http://www.heartfailure.no/

Samarbeid

Utstrakt nasjonalt og internasjonalt samarbeid innen hjerteforskning

Emneord: Hjertesvikt, Hjerte, Molekylær

Lunde, Ida Gjervold; Aronsen, Jan Magnus; Melleby, Arne Olav; Strand, Mari Elen; Skogestad, Jonas & Bendiksen, Bård Andre [Vis alle 11 forfattere av denne artikkelen] (2022). Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy. Molecular Biology Reports. ISSN 0301-4851. doi: 10.1007/s11033-022-07985-y.
Støle, Thea Parsberg; Lunde, Marianne; Shen, Xin; Martinsen, Marita; Lunde, Per Kristian & Li, Jia [Vis alle 12 forfattere av denne artikkelen] (2022). The female syndecan-4<sup>−/−</sup> heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 10. doi: 10.3389/fcell.2022.908126.
Romaine, Andreas; Melleby, Arne Olav; Alam, Jahedul; Lobert, Viola; Lu, Ning & Lockwood, Francesca Eve [Vis alle 13 forfattere av denne artikkelen] (2022). Integrin α11β1 and syndecan-4 dual receptor ablation attenuates cardiac hypertrophy in the pressure overloaded heart. American Journal of Physiology. Heart and Circulatory Physiology. ISSN 0363-6135. 322(6), s. H1057–H1071. doi: 10.1152/ajpheart.00635.2021.
Udjus, Camilla; Sjaastad, Ivar; Hjørnholm, Ulla; Tunestveit, Torbjørn K.; Hoffmann, Pavel & Hinojosa, Alexis [Vis alle 11 forfattere av denne artikkelen] (2022). Extreme altitude induces divergent mass reduction of right and left ventricle in mountain climbers. Physiological Reports. ISSN 2051-817X. 10(3). doi: 10.14814/phy2.15184.
Berge, Kristian; Brynildsen, Jon; Røysland, Ragnhild; Strand, Heidi; Christensen, Geir & Høiseth, Arne Didrik [Vis alle 9 forfattere av denne artikkelen] (2022). Prognostic value of cardiac biomarkers and National Early Warning Score 2 in acute dyspnoea. Open heart. ISSN 2053-3624. 9(1). doi: 10.1136/openhrt-2021-001938.
Carlson, Cathrine Rein; Aronsen, Jan Magnus; Bergan Dahl, Anna; Moutty, Marie Christine; Lunde, Marianne & Lunde, Per Kristian [Vis alle 22 forfattere av denne artikkelen] (2021). AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR. Circulation Research. ISSN 0009-7330. 130(1), s. 27–44. doi: 10.1161/CIRCRESAHA.120.317976. Fulltekst i vitenarkiv
Myhre, Peder Langeland; Ottesen, Anett Hellebø; Faaren, Arne L.; Tveit, Sjur Hansen; Springett, Jon & Pyylampi, Johanna [Vis alle 11 forfattere av denne artikkelen] (2021). Performance of a Novel Research-Use-Only Secretoneurin ELISA in Patients with Suspected Acute Coronary Syndrome: Comparison with an Established Secretoneurin Radioimmunoassay. Cardiology. ISSN 0008-6312. 146(5), s. 566–574. doi: 10.1159/000517444. Fulltekst i vitenarkiv
Aakre, Kristin Moberg; Ottesen, Anett Hellebø; Strand, Heidi; Faaren, Arne L.; Alaour, Bashir & Torsvik, Janniche [Vis alle 11 forfattere av denne artikkelen] (2021). Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis. Clinical Biochemistry. ISSN 0009-9120. 98, s. 74–77. doi: 10.1016/j.clinbiochem.2021.09.014. Fulltekst i vitenarkiv
Rypdal, Karoline Bjarnesdatter; Murugan Erusappan, Pugazendhi; Melleby, Arne Olav; Seifert, Deborah E.; Palmero, Sheryl & Strand, Mari Elen [Vis alle 13 forfattere av denne artikkelen] (2021). The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts. Scientific Reports. ISSN 2045-2322. 11(1), s. 1–15. doi: 10.1038/s41598-021-99032-2. Fulltekst i vitenarkiv
Rutkovskiy, Arkady; Lyngbakken, Magnus; Dahl, Mai Britt; Bye, Anja; Pedersen, Marit Holmefjord & Wisløff, Ulrik [Vis alle 10 forfattere av denne artikkelen] (2021). Circulating MicroRNA-210 Concentrations in Patients with Acute Heart Failure: Data from the Akershus Cardiac Examination 2 Study. Clinical Chemistry. ISSN 0009-9147. 67(6), s. 889–898. doi: 10.1093/clinchem/hvab030. Fulltekst i vitenarkiv
Norden, Einar Sjaastad; Bendiksen, Bård Andre; Andresen, Henriette; Bergo, Kaja Knudsen; Espe, Emil Knut Stenersen & Hasic, Almira [Vis alle 12 forfattere av denne artikkelen] (2021). Sacubitril/valsartan ameliorates cardiac hypertrophy and preserves diastolic function in cardiac pressure overload. ESC Heart Failure. ISSN 2055-5822. 8(2), s. 918–927. doi: 10.1002/ehf2.13177.
Alam, Jahedul; Musiime, Moses; Romaine, Andreas; Sawant, Mugdha; Melleby, Arne Olav & Lu, Ning [Vis alle 9 forfattere av denne artikkelen] (2020). Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase. Matrix Biology Plus. 8. doi: 10.1016/j.mbplus.2020.100045.
Mathiesen, Sabrina Bech; Lunde, Marianne; Stensland, Maria; Martinsen, Marita; Nyman, Tuula Anneli & Christensen, Geir Arve [Vis alle 7 forfattere av denne artikkelen] (2020). The cardiac syndecan-2 interactome. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 8:792, s. 1–18. doi: 10.3389/fcell.2020.00792. Fulltekst i vitenarkiv
Berge, Kristian; Lyngbakken, Magnus; Myhre, Peder Langeland; Brynildsen, Jon; Røysland, Ragnhild & Strand, Heidi [Vis alle 10 forfattere av denne artikkelen] (2020). High-sensitivity cardiac troponin T and N-terminal pro-B-type natriuretic peptide in acute heart failure: Data from the ACE 2 study. Clinical Biochemistry. ISSN 0009-9120. s. 1–7. doi: 10.1016/j.clinbiochem.2020.11.009. Fulltekst i vitenarkiv
Herum, Kate Louise Møller; Romaine, Andreas; Wang, Ariel; Melleby, Arne Olav; Strand, Mari Elen & Pacheco, Julian [Vis alle 16 forfattere av denne artikkelen] (2020). Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin. Journal of the American Heart Association (JAHA). ISSN 2047-9980. 9(3). doi: 10.1161/JAHA.119.013518. Fulltekst i vitenarkiv
Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Pisconti, Addolorata; Høst, Vibeke & Lunde, Marianne [Vis alle 11 forfattere av denne artikkelen] (2020). Syndecan-4–/– Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. doi: 10.3389/fcell.2020.00730. Fulltekst i vitenarkiv
Mohammadzadeh, Naiyereh; Melleby, Arne Olav; Palmero, Sheryl; Sjaastad, Ivar; Chakravarti, Shukti & Engebretsen, Kristin V Thunheim [Vis alle 9 forfattere av denne artikkelen] (2020). Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload. Cardiology. ISSN 0008-6312. 145(3), s. 187–198. doi: 10.1159/000505318.
Udjus, Camilla; Fadila, Cero; Halvorsen, Bente; Behmen, Dina; Carlson, Cathrine Rein & Bendiksen, Bård Andre [Vis alle 14 forfattere av denne artikkelen] (2019). Caspase-1 induces smooth muscle cell growth in hypoxia-induced pulmonary hypertension. American Journal of Physiology - Lung cellular and Molecular Physiology. ISSN 1040-0605. 316(6), s. L999–L1012. doi: 10.1152/ajplung.00322.2018. Fulltekst i vitenarkiv
Brynildsen, Jon; Myhre, Peder Langeland; Lyngbakken, Magnus; Klæboe, Lars Gunnar; Stridsberg, Mats & Christensen, Geir Arve [Vis alle 9 forfattere av denne artikkelen] (2019). Circulating secretoneurin concentrations in patients with moderate to severe aortic stenosis. Clinical Biochemistry. ISSN 0009-9120. 71, s. 17–23. doi: 10.1016/j.clinbiochem.2019.06.008. Fulltekst i vitenarkiv
Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Andenæs, Kine; Strand, Mari Elen; Aronsen, Jan Magnus & Skrbic, Biljana [Vis alle 15 forfattere av denne artikkelen] (2019). The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload. Scientific Reports. ISSN 2045-2322. 9:9206, s. 1–13. doi: 10.1038/s41598-019-45651-9. Fulltekst i vitenarkiv
Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Eken, Olav Søvik; Sadredini, Mani; Myhre, Peder Langeland & Shen, Xin [Vis alle 24 forfattere av denne artikkelen] (2019). Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia. Circulation: Arrhythmia and Electrophysiology. ISSN 1941-3149. 12(4). doi: 10.1161/CIRCEP.118.007045. Fulltekst i vitenarkiv
Mathiesen, Sabrina Bech; Lunde, Marianne; Aronsen, Jan Magnus; Romaine, Andreas; Kaupang, Anita & Martinsen, Marita [Vis alle 11 forfattere av denne artikkelen] (2019). The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP). Journal of Biological Chemistry. ISSN 0021-9258. 294(22), s. 8717–8731. doi: 10.1074/jbc.RA118.006423. Fulltekst i vitenarkiv
Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Norden, Einar Sjaastad; Buonarati, Olivia R. & Cataliotti, Alessandro [Vis alle 10 forfattere av denne artikkelen] (2019). Cardiomyocyte substructure reverts to an immature phenotype during heart failure. Journal of Physiology. ISSN 0022-3751. 597(7), s. 1833–1853. doi: 10.1113/JP277273. Fulltekst i vitenarkiv
Brynildsen, Jon; Petaja, Liisa; Myhre, Peder Langeland; Lyngbakken, Magnus; Nygård, Ståle & Stridsberg, Mats [Vis alle 11 forfattere av denne artikkelen] (2019). Circulating Secretoneurin Concentrations After Cardiac Surgery: Data From the FINNish Acute Kidney Injury Heart Study. Critical Care Medicine. ISSN 0090-3493. 47(5), s. e412–e419. doi: 10.1097/CCM.0000000000003670.
Røe, Åsmund Treu; Ruud, Marianne; Espe, Emil Knut Stenersen; Manfra, Ornella; Longobardi, S & Aronsen, Jan Magnus [Vis alle 16 forfattere av denne artikkelen] (2019). Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression. Cardiovascular Research (CVR). ISSN 0008-6363. 115(4), s. 752–764. doi: 10.1093/cvr/cvy257.
Yaddehi Gamage, Thilini Hansamali Gamage; Gunnes, Gjermund; Lee, Robert Hugh; Louch, William Edward; Holmgren, Asbjørn & Bruton, Joseph D. [Vis alle 19 forfattere av denne artikkelen] (2018). STIM1 R304W causes muscle degeneration and impaired platelet activation in mice. Cell Calcium. ISSN 0143-4160. 76, s. 87–100. doi: 10.1016/j.ceca.2018.10.001. Fulltekst i vitenarkiv Vis sammendrag
STIM1 and ORAI1 regulate store-operated Ca2+ entry (SOCE) in most cell types, and mutations in these proteins have deleterious and diverse effects. We established a mouse line expressing the STIM1 R304 W gain-of-function mutation causing Stormorken syndrome to explore effects on organ and cell physiology. While STIM1 R304 W was lethal in the homozygous state, surviving mice presented with reduced growth, skeletal muscle degeneration, and reduced exercise endurance. Variable STIM1 expression levels between tissues directly impacted cellular SOCE capacity. In contrast to patients with Stormorken syndrome, STIM1 was downregulated in fibroblasts from Stim1R304W/R304W mice, which maintained SOCE despite constitutive protein activity. In studies using foetal liver chimeras, STIM1 protein was undetectable in homozygous megakaryocytes and platelets, resulting in impaired platelet activation and absent SOCE. These data indicate that downregulation of STIM1 R304 W effectively opposes the gain-of-function phenotype associated with this mutation, and highlight the importance of STIM1 in skeletal muscle development and integrity.
Pervez, Mohammad Osman; Winther, Jacob Andreas; Brynildsen, Jon; Strand, Heidi; Christensen, Geir Arve & Høiseth, Arne Didrik [Vis alle 11 forfattere av denne artikkelen] (2018). Prognostic and diagnostic significance of mid-regional pro-atrial natriuretic peptide in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 Study. Biomarkers. ISSN 1354-750X. s. 1–11. doi: 10.1080/1354750X.2018.1474258.
Røsjø, Helge; Masson, Serge; Caironi, Pietro; Stridsberg, Mats; Magnoli, Michela & Christensen, Geir Arve [Vis alle 12 forfattere av denne artikkelen] (2018). Prognostic value of secretoneurin in patients with severe sepsis and septic shock: Data from the albumin Italian outcome sepsis study. Critical Care Medicine. ISSN 0090-3493. 46(5), s. e404–e410. doi: 10.1097/CCM.0000000000003050. Fulltekst i vitenarkiv
Andenæs, Kine; Lunde, Ida Gjervold; Mohammadzadeh, Naiyereh; Dahl, Christen Peder; Aronsen, Jan Magnus & Strand, Mari Elen [Vis alle 11 forfattere av denne artikkelen] (2018). The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling. PLOS ONE. ISSN 1932-6203. 13(7), s. 1–20. doi: 10.1371/journal.pone.0201422. Fulltekst i vitenarkiv
Berge, Kristian; Lyngbakken, Magnus; Einvik, Gunnar; Winther, Jacob Andreas; Brynildsen, Jon & Røysland, Ragnhild [Vis alle 11 forfattere av denne artikkelen] (2018). Diagnostic and prognostic properties of procalcitonin in patients with acute dyspnea: Data from the ACE 2 Study. Clinical Biochemistry. ISSN 0009-9120. 59, s. 62–68. doi: 10.1016/j.clinbiochem.2018.07.006.
Melleby, Arne Olav; Romaine, Andreas; Aronsen, Jan Magnus; Veras, Ioanni; Zhang, Lili & Sjaastad, Ivar [Vis alle 8 forfattere av denne artikkelen] (2018). A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice. Cardiovascular Research (CVR). ISSN 0008-6363. doi: 10.1093/cvr/cvy141. Fulltekst i vitenarkiv
Christensen, Geir Arve; Herum, Kate Louise Møller & Lunde, Ida Gjervold (2018). Sweet, yet underappreciated: Proteoglycans and extracellular Matrix remodeling in heart disease. Matrix Biology. ISSN 0945-053X. 75-76, s. 286–299. doi: 10.1016/j.matbio.2018.01.001.
Lyngbakken, Magnus Nakrem; Pervez, Mohammad Osman; Brynildsen, Jon; Pedersen, Marit Holmefjord; Sølvernes, Janne & Christensen, Geir Arve [Vis alle 9 forfattere av denne artikkelen] (2018). Fibroblast growth factor 23 in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. Clinical Biochemistry. ISSN 0009-9120. 52, s. 41–47. doi: 10.1016/j.clinbiochem.2017.10.015. Fulltekst i vitenarkiv
Romaine, Andreas; Sørensen, Ida Wiig; Zeltz, Cedric; Lu, Ning; Erusappan, Pugazendhi Murugan & Melleby, Arne Olav [Vis alle 15 forfattere av denne artikkelen] (2017). Overexpression of integrin α11 induces cardiac fibrosis in mice. Acta Physiologica Scandinavica. ISSN 0001-6772. 222:e13025(2), s. 1–17. doi: 10.1111/apha.12932.
Herum, Kate Louise Møller; Lunde, Ida Gjervold; McCulloch, Andrew D. & Christensen, Geir Arve (2017). The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart. Journal of Clinical Medicine. ISSN 2077-0383. 6(53). doi: 10.3390/jcm6050053. Fulltekst i vitenarkiv
Myhre, Peder Langeland; Stridsberg, Mats; Linko, Rita; Okkonen, Marjatta; Nygård, Ståle & Christensen, Geir Arve [Vis alle 9 forfattere av denne artikkelen] (2017). Circulating chromogranin B levels in patients with acute respiratory failure: data from the FINNALI Study. Biomarkers. ISSN 1354-750X. 22(8), s. 775–781. doi: 10.1080/1354750X.2016.1269200. Fulltekst i vitenarkiv
Winther, Jacob Andreas; Brynildsen, Jon; Høiseth, Arne Didrik; Strand, Heidi; Følling, Ivar & Christensen, Geir Arve [Vis alle 9 forfattere av denne artikkelen] (2017). Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: Data from the ACE 2 study. Respiratory Research. ISSN 1465-9921. 18(184). doi: 10.1186/s12931-017-0665-z. Fulltekst i vitenarkiv
Ottesen, Anett Hellebø; Christensen, Geir Arve; Omland, Torbjørn & Røsjø, Helge (2017). Glycosylated Chromogranin A: Potential Role in the Pathogenesis of Heart Failure. Current Heart Failure Reports. ISSN 1546-9530. 14. doi: 10.1007/s11897-017-0360-x. Fulltekst i vitenarkiv
Pervez, Mohammad Osman; Lyngbakken, Magnus Nakrem; Myhre, Peder Langeland; Brynildsen, Jon; Langsjøen, Eva Camilla & Høiseth, Arne Didrik [Vis alle 9 forfattere av denne artikkelen] (2017). Mid-regional pro-adrenomedullin in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. Clinical Biochemistry. ISSN 0009-9120. 50(7-8), s. 394–400. doi: 10.1016/j.clinbiochem.2016.12.010. Fulltekst i vitenarkiv
Abraityte, Judita Aurelija; Lunde, Ida Gjervold; Askevold, Erik Tandberg; Michelsen, Annika; Christensen, Geir Arve & Aukrust, Pål [Vis alle 14 forfattere av denne artikkelen] (2017). Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy. Scientific Reports. ISSN 2045-2322. 7(1). doi: 10.1038/s41598-017-03625-9. Fulltekst i vitenarkiv
Dhondup, Yangchen; Sjaastad, Ivar; Sandanger, Øystein; Aronsen, Jan Magnus; Ahmed, Muhammad Shakil & Attramadal, Håvard [Vis alle 14 forfattere av denne artikkelen] (2017). Toll-like receptor 9 promotes survival in SERCA2a KO heart failure mice. Mediators of Inflammation. ISSN 0962-9351. 2017:9450439, s. 1–11. doi: 10.1155/2017/9450439. Fulltekst i vitenarkiv
Abraityte, Judita Aurelija; Vinge, Leif Erik; Askevold, Erik Tandberg; Lekva, Tove; Michelsen, Annika & Ranheim, Trine [Vis alle 16 forfattere av denne artikkelen] (2017). Wnt5a is elevated in heart failure and affects cardiac fibroblast function. Journal of Molecular Medicine. ISSN 0946-2716. 95(7), s. 767–777. doi: 10.1007/s00109-017-1529-1.
Norum, Hilde Margrethe; Broch, Kaspar; Michelsen, Annika; Lunde, Ida Gjervold; Lekva, Tove & Abraityte, Judita Aurelija [Vis alle 14 forfattere av denne artikkelen] (2017). The Notch Ligands DLL1 and Periostin Are Associated with Symptom Severity and Diastolic Function in Dilated Cardiomyopathy. Journal of Cardiovascular Translational Research. ISSN 1937-5387. s. 1–10. doi: 10.1007/s12265-017-9748-y.
Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland & Johansen, Rune Forstrøm [Vis alle 15 forfattere av denne artikkelen] (2017). Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis. Circulation: Heart Failure. ISSN 1941-3289. 10(2). doi: 10.1161/CIRCHEARTFAILURE.116.003675.
Olsen, Maria Belland; Hildrestrand, Gunn Annette; Scheffler, Katja; Vinge, Leif Erik; Alfsnes, Katrine & Palibrk, Vuk [Vis alle 29 forfattere av denne artikkelen] (2017). NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell reports. ISSN 2211-1247. 18, s. 82–92. doi: 10.1016/j.celrep.2016.12.009. Fulltekst i vitenarkiv
Myhre, Peder Langeland; Ottesen, Anett Hellebø; Okkonen, Marjatta; Linko, Rita; Stridsberg, Mats & Nygård, Ståle [Vis alle 10 forfattere av denne artikkelen] (2016). Prognostic value of secretoneurin in patients with acute respiratory failure:Data from the FINNALI study. Clinical Chemistry. ISSN 0009-9147. 62(10), s. 1380–1389. doi: 10.1373/clinchem.2016.258764.
Røsjø, Helge; Stridsberg, Mats; Ottesen, Anett Hellebø; Nygård, Ståle; Christensen, Geir Arve & Pettilä, Ville [Vis alle 11 forfattere av denne artikkelen] (2016). Prognostic Value of Secretoneurin in Critically Ill Patients with Infections. Critical Care Medicine. ISSN 0090-3493. 44(10), s. 1882–1890. doi: 10.1097/CCM.0000000000001832.
Winther, Jacob Andreas; Brynildsen, Jon; Høiseth, Arne Didrik; Følling, Ivar; Brekke, Pål Haugar & Christensen, Geir Arve [Vis alle 10 forfattere av denne artikkelen] (2016). Prevalence and prognostic significance of hyponatremia in patients with acute exacerbation of chronic obstructive pulmonary disease: Data from the akershus cardiac examination (ACE) 2 study. PLOS ONE. ISSN 1932-6203. 11:e0161232(8). doi: 10.1371/journal.pone.0161232. Fulltekst i vitenarkiv
Melleby, Arne Olav; Strand, Mari Elen; Romaine, Andreas; Herum, Kate Louise Møller; Skrbic, Biljana & Dahl, Christen Peder [Vis alle 11 forfattere av denne artikkelen] (2016). The heparan sulfate proteoglycan glypican-6 is upregulated in the failing heart, and regulates cardiomyocyte growth through ERK1/2 Signaling. PLOS ONE. ISSN 1932-6203. 11(10). doi: 10.1371/journal.pone.0165079.
Lunde, Ida Gjervold; Herum, Kate Louise Møller; Carlson, Cathrine Rein & Christensen, Geir Arve (2016). Syndecans in heart fibrosis. Cell and Tissue Research. ISSN 0302-766X. 365(3), s. 539–552. doi: 10.1007/s00441-016-2454-2.
Frisk, Michael; Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Røe, Åsmund Treu & Zhang, Lili [Vis alle 11 forfattere av denne artikkelen] (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research (CVR). ISSN 0008-6363. doi: 10.1093/cw111.
Høiseth, Arne Didrik; Brynildsen, Jon; Hagve, Tor-Arne; Christensen, Geir Arve; Søyseth, Vidar & Omland, Torbjørn [Vis alle 7 forfattere av denne artikkelen] (2016). The influence of heart failure co-morbidity on high-sensitivity troponin T levels in COPD exacerbation in a prospective cohort study: Data from the Akershus cardiac examination (ACE) 2 study. Biomarkers. ISSN 1354-750X. 21(2), s. 173–179. doi: 10.3109/1354750X.2015.1126645.
Einvik, Gunnar; Dammen, Toril; Høiseth, Arne Didrik; Brynildsen, Jon; Hagve, Tor-Arne & Christensen, Geir Arve [Vis alle 8 forfattere av denne artikkelen] (2015). Psychological distress and mortality in patients with acute dyspnea: Data from the Akershus Cardiac Examination (ACE) 2 Study. General Hospital Psychiatry. ISSN 0163-8343. 37(6), s. 548–553. doi: 10.1016/j.genhosppsych.2015.07.007.
Brynildsen, Jon; Høiseth, Arne Didrik; Nygård, Ståle; Hagve, Tor-Arne; Christensen, Geir Arve & Omland, Torbjørn [Vis alle 7 forfattere av denne artikkelen] (2015). Diagnostisk treffsikkerhet for hjertesvikt – data fra Akershus hjerteundersøkelse 2. Tidsskrift for Den norske legeforening. ISSN 0029-2001. 135(19), s. 1738–1744. doi: 10.4045/tidsskr.14.1174.
Fadila, Cero; Hillestad, Vigdis; Sjaastad, Ivar; Yndestad, Arne; Aukrust, Pål & Ranheim, Trine [Vis alle 15 forfattere av denne artikkelen] (2015). Absence of the inflammasone adaptor ASC reduces hypoxia-induced pulmonary hypertension in mice. American Journal of Physiology - Lung cellular and Molecular Physiology. ISSN 1040-0605. 309, s. L378–L387. doi: 10.1152/ajplung.00342.2014.

Se alle arbeider i Cristin

Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Pisconti, Addolorate & Lunde, Marianne [Vis alle 11 forfattere av denne artikkelen] (2019). Extracellular Matrix remodeling and multiple signaling pathways are regulated by syndecan-4 during myogenesis.
Udjus, Camilla; Cero, Fadila; Halvorsen, Bente; Aukrust, Pål; Christensen, Geir Arve & Skjønsberg, Ole Henning [Vis alle 7 forfattere av denne artikkelen] (2018). Inhibition of caspase-1 reduces hypoxia-induced pulmonary hypertension by downregulating smooth muscle cell growth.
Rønning, Sissel Beate; Carlson, Cathrine Rein; Aronsen, Jan Magnus; Høst, Vibeke; Liland, Kristian Hovde & Stang, Espen [Vis alle 10 forfattere av denne artikkelen] (2017). Syndecan-4 is a skeletal muscle regenerator and is important for normal skeletal muscle fibre development.
Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Laver, Derek R; Myhre, Peder Langeland; Dalhus, Bjørn & Lunde, Per Kristian [Vis alle 14 forfattere av denne artikkelen] (2017). Secretoneurin is an Endogenous CaMKII Inhibitor That Attenuates Ca2+-Dependent Arrhythmogenesis. Circulation. ISSN 0009-7322. 136.
Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazaukaite, Monika; Sjaastad, Ivar & Christensen, Geir Arve [Vis alle 7 forfattere av denne artikkelen] (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Zhang, Lili & Norseng, Per Andreas [Vis alle 10 forfattere av denne artikkelen] (2016). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
Mohammadzadeh, Naiyereh; Engebretsen, Kristin V Thunheim; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen & Marstein, Henriette [Vis alle 14 forfattere av denne artikkelen] (2016). Lack of the extracellular matrix proteoglycan lumican leads to cardiac dysfunction in response to pressure overload.
Mohammadzadeh, Naiyereh; Engebretsen, Kristin; Lunde, Ida Gjervold; Sjaastad, Ivar; Strand, Mari Elen & Marstein, Henriette [Vis alle 14 forfattere av denne artikkelen] (2016). Lack of the extracellular matrix proteoglycan lumican leads to ventricular dilatation, attenuated hypertrophy and contractile dysfunction in response to pressure overload.
Romaine, Andreas; Sørensen, Ida Wiig; Melleby, Arne Olav; Zeltz, Cedric; Zhang, Lili & Bendiksen, Bård Andre [Vis alle 12 forfattere av denne artikkelen] (2016). Overexpression of integrin a11 induces cardiac hypertrophy and fibrosis.
Melleby, Arne Olav; Strand, Mari Elen; Herum, Kate Louise Møller; Skrbic, Biljana; Dahl, Christen Peder & Sjaastad, Ivar [Vis alle 10 forfattere av denne artikkelen] (2016). Glypican-6 is upregulated in heart failure and mediates cardiomyocyte growth through ERK1/2 signaling.
Mathiesen, Sabrina Bech; Lunde, Marianne; Christensen, Geir Arve & Carlson, Cathrine Rein (2016). Mass spectrometry analysis of cytoplasmic binding partners of cardiac syndecan - 2.
Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor & Unger, Andreas [Vis alle 13 forfattere av denne artikkelen] (2016). Study of a mouse with proximal titin A-band truncation reveals disease mechanisms and modifiers of titin dilated cardiomyopathy.
Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2016). BIN1 triggers t-tubule development in cardiomyocytes.
Ruud, Marianne; Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Jølle, Guro Five & Aakhus, Svend [Vis alle 15 forfattere av denne artikkelen] (2016). Mechanical load regulates cardiomyocyte t-tubular structure and Ca2+ homeostasis.
Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Sejersted, Ole M; Sjaastad, Ivar & Christensen, Geir Arve [Vis alle 7 forfattere av denne artikkelen] (2016). Sarcolemmal structure and function revert to an immature phenotype in failing cardiomyocytes.
Mathiesen, Sabrina Bech; Lunde, Marianne; Christensen, Geir Arve & Carlson, Cathrine Rein (2016). Mass spectrometry analysis of cytoplasmic binding partners of cardiac syndecan-2.
Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor & Unger, Andreas [Vis alle 13 forfattere av denne artikkelen] (2016). Titin A-band truncation mutation in mice causes stress-induced dilated cardiomyopathy.
Aronsen, Jan Magnus; Singbrant, Sofie; Christensen, Geir Arve & Iversen, Per Ole (2016). Evidence for splenic stress-induced erythropoiesis in mice with post-infarction heart failure.
Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Gelazauskaite, Monika; Sjaastad, Ivar & Christensen, Geir Arve [Vis alle 7 forfattere av denne artikkelen] (2016). The heparanase-syndecan-4 axis in the heart: upregulation in response to immune activation indicates a role in cardiac inflammation.
Rønning, Sissel Beate; Carlson, Cathrine Rein; Høst, Vibeke; Aronsen, Jan Magnus; Liland, Kristian Hovde & Stang, Espen [Vis alle 9 forfattere av denne artikkelen] (2016). Syndecan-4 is important for normal skeletal muscle fibre development .
Rønning, Sissel Beate; Carlson, Cathrine Rein; Hollung, Kristin; Pedersen, Mona Elisabeth; Stang, Espen & Kolset, Svein Olav [Vis alle 7 forfattere av denne artikkelen] (2015). Syndecan-4 in skeletal muscle development and regeneration.
Rønning, Sissel Beate; Carlson, C. R.; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve & Hollung, Kristin [Vis alle 7 forfattere av denne artikkelen] (2015). Syndecan-4 in skeletal muscle development and regeneration.
Ottesen, Anett Hellebø; Laver, Derek; Christensen, Geir Arve; Røsjø, Helge & Louch, William Edward (2015). Secretoneurin a novel endogenous CaMKIIð inhibitor, inhibits Ca2+ dependent arrhythmogenesis.
Sandbu, Ragnhild Askeland; Dahl, Mai Britt; Ottesen, Anett Hellebø; Jørgensen, M; Stridsberg, Mats & Sjaastad, Ivar [Vis alle 10 forfattere av denne artikkelen] (2015). Chromogranin A is glycosylated in acute heart failure and this is associated with reduced processing to the functional peptide catestatin and increased mortality.
Frisk, Michael; Aronsen, Jan Magnus; Dahl, Christen Peder; Lunde, Ida Gjervold; Jølle, Guro Five & Almaas, Victor [Vis alle 13 forfattere av denne artikkelen] (2015). Maintained cardiomyocyte t-tubule structure and function in patients with non-dilated hypertrophy.
Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Johansen, Rune F.; Stridsberg, Mats & Jarstadmarken, Hilde [Vis alle 12 forfattere av denne artikkelen] (2015). Chromogranin A is a potent prognostic biomarker in acute heart failure, and its fragment catestatin regulates cardiomyocyte calcium homeostasis by CaMKII inhibition.
Ottesen, Anett Hellebø; Carlson, Cathrine Rein; Louch, William Edward; Dahl, Mai Britt; Sandbu, Ragnhild Askeland & Johansen, Rune F. [Vis alle 15 forfattere av denne artikkelen] (2015). Enhanced myocardial chromogranin A glycosylation in acute heart failure: reduced processing and potential impact on cardiomyocyte calcium homeostasis.
Røsjø, Helge; Masson, Serge; Caironi, Pietro; Stridsberg, Mats; Fanizza, Caterina & Christensen, Geir Arve [Vis alle 11 forfattere av denne artikkelen] (2015). The novel cardiac biomarker secretoneurin provides independent prognostic information in severe sepsis and septic shock: data from the ALBIOS study. Circulation. ISSN 0009-7322. 132(A14598).
Lunde, Ida Gjervold; Wakimoto, Hiroko; Jianming, Jiang; Burke, Michael A.; Soukoulis, Victor & Unger, Andreas [Vis alle 12 forfattere av denne artikkelen] (2015). Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy.
Mohammadzadeh, Naiyereh; Andenæs, Kine; Engebretsen, Kristin V.; Lunde, Ida Gjervold; Sjaastad, Ivar & Marstein, Henriette [Vis alle 12 forfattere av denne artikkelen] (2015). The role of lumican in Cardiac pressure overload.
Rønning, Sissel Beate; Carlson, Cathrine Rein; Stang, Espen; Kolset, Svein Olav; Christensen, Geir Arve & Hollung, Kristin [Vis alle 7 forfattere av denne artikkelen] (2015). Syndecan-4 is important for skeletal muscle development.
Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2015). BIN1 regulates t-tubule growth during cardiac development and disease.
Lipsett, David Bruce; Frisk, Michael; Aronsen, Jan Magnus; Singh, Neha; Sejersted, Ole M & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2015). BIN1 regulates t-tubule growth during cardiac development and diseases.
Lipsett, David Bruce; Frisk, Michael; Singh, Neha; Aronsen, Jan Magnus; Marszalec, William & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2015). Bridging integrator 1 (B1N1) initiates t-tubule growth cardiac development and disease.
Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
Ruud, Marianne; Frisk, Michael; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas & Sjaastad, Ivar [Vis alle 9 forfattere av denne artikkelen] (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca2+ homeostasis.
Udjus, Camilla; Cero, Fadila; Christensen, Geir Arve; Skjønsberg, Ole Henning & Larsen, Karl-Otto (2015). The role of caspase-1 in pulmonary hypertension.
Ruud, Marianne; Espe, Emil Knut Stenersen; Aronsen, Jan Magnus; Norseng, Per Andreas; Sjaastad, Ivar & Sejersted, Ole M [Vis alle 8 forfattere av denne artikkelen] (2015). Elevated ventricular wall stress disrupts cardiomyocyte t-tubular structure and Ca 2+ homeostasis.
Lunde, Ida Gjervold; Wakimoto, Hiroko; Jiang, Jianming; Burke, Michael A.; Soukoulis, Victor & Unger, Andreas [Vis alle 12 forfattere av denne artikkelen] (2015). 7th Joint Scandinavian Conference in Cardiothoracic Surgery.
Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Soukoulis, Victor; Linke, Wolfgang A. & Gorham, joshua [Vis alle 10 forfattere av denne artikkelen] (2015). Proximal titin A-band truncation causes dilated cardiomyopathy in response to increased afterload in mice.
Lunde, Ida Gjervold; Wakimoto, Hiroko; Burke, Michael A.; Soukoulis, Victor; Linke, Wolfgang E. & Gorham, Joshua [Vis alle 10 forfattere av denne artikkelen] (2015). Titin A-band truncation in mice causes stress-induced dilated cardiomyopathy.
Carlson, Cathrine Rein; Nygård, Ståle; Sirnes, Solveig; Jarstadmarken, Hilde; Martinsen, Marita & Lunde, Marianne [Vis alle 9 forfattere av denne artikkelen] (2015). A protein-protein interaction (PPI) map of cardiac syndecan-4.
Cero, Fadila; Larsen, Karl-Otto; Hillestad, Vigdis; Olsen, Maria Belland; Udjus, Camilla & Sjaastad, Ivar [Vis alle 11 forfattere av denne artikkelen] (2015). The inflammasome adaptor ASC mediates pulmonary artery remodelling.
Romaine, Andreas; Herum, Kate Louise Møller; Sørensen, Ida Wiig; Hasic, Almira; Sjaastad, Ivar & Gullberg, Donald [Vis alle 7 forfattere av denne artikkelen] (2015). Syndecan-4 regulates profibrotic a11B1 integrin expression in the pressure-overloaded heart.

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Publisert 13. apr. 2011 11:37 - Sist endret 5. okt. 2020 12:07