Kristina Haugaa

• Quattrone, Alessia; Lie, Øyvind Haugen; Nestaas, Eirik; de Lange, Charlotte; Try, Kirsti; Lindberg, Harald L; Skulstad, Helge; Erikssen, Gunnar; Edvardsen, Thor; Haugaa, Kristina & Estensen, Mette-Elise (2021). Impact of pregnancy and risk factors for ventricular arrhythmias in women with tetralogy of Fallot. Open heart.  ISSN 2053-3624.  8(1) . doi: 10.1136/openhrt-2020-001400 Vis sammendrag

  Objective: Patients with tetralogy of Fallot (TOF) have high survival rates 30 years after surgical repair. Many patients experience pregnancy; however, the effects of pregnancy on the long-term cardiovascular outcome are not well known. We investigated the association of pregnancy and cardiac function with occurrence of ventricular arrhythmia (VA) in women with TOF. Methods: We recruited 80 women with repaired TOF from the national database. Holter monitoring or implanted devices detected VA, defined as non-sustained or sustained ventricular tachycardia or aborted cardiac arrest. All patients underwent echocardiography. Blood tests included NT-proBNP (N-terminal pro-brain natriuretic peptide). Results: 55 (69%) women had experienced pregnancy. Mean age was lower in nulliparous compared with those with children (30±9 vs 40±9, p<0.01).VA had occurred in 17 (21%) women. Prevalence of VA was higher in women who had experienced pregnancy (n=16, 94%) compared with nulliparous (n=1, 6%) (p=0.02), also when adjusted for age (OR 12.9 (95% CI 1.5 to 113.2), p=0.02).Right ventricular mechanical dispersion was more pronounced in patients with VA (50±8 ms vs 39±14 ms, p=0.01, age-adjusted OR 2.1 (95% CI 1.3 to 7.5), p=0.01). NT-proBNP was also a marker of VA (211 ng/L (127 to 836) vs 139 ng/L (30 to 465), p=0.007). NT-proBNP >321 ng/L (normal values <170 ng/L) detected women with VA (p=0.019), also independent of age (OR 7.2 (95% CI 1.7 to 30.1), p=0.007). Conclusion: Pregnancy was associated with higher prevalence of VA among women with TOF. Right ventricular mechanical dispersion and NT-proBNP were age-independent markers of VA. These may have importance for pregnancy counselling and risk stratification. Keywords: Fallots tetralogy; arrhythmias; echocardiography

• Ajmone Marsan, Nina; Michalski, Blazej; Cameli, Matteo; Podlesnikar, Tomaz; Manka, Robert; Sitges, Marta; Dweck, Mark R. & Haugaa, Kristina (2020). EACVI survey on standardization of cardiac chambers quantification by transthoracic echocardiography. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(2), s 119- 123 . doi: 10.1093/ehjci/jez297
• Badano, Luigi P.; Muraru, Denisa; Parati, Gianfranco; Haugaa, Kristina & Voigt, Jens-Uwe (2020). How to do right ventricular strain. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(8), s 825- 827 . doi: 10.1093/ehjci/jeaa126 Fulltekst i vitenarkiv.
• Bjerring, Anders W.; Landgraff, Hege Elisabeth W.; Leirstein, Svein; Haugaa, Kristina; Edvardsen, Thor; Sarvari, Sebastian & Hallén, Jostein (2020). From talented child to elite athlete: The development of cardiac morphology and function in a cohort of endurance athletes from age 12 to 18. European Journal of Preventive Cardiology (EJPC).  ISSN 2047-4873. . doi: 10.1177/2047487320921317 Fulltekst i vitenarkiv. Vis sammendrag

  Background: Adult athletes undergo cardiac adaptions in what is known as the “athlete’s heart”. Cardiac adaptations in young athletes have not been described in longitudinal studies but have previously been believed to be uniform in nature. Methods: Seventy-six cross-country skiers were assessed at age 12. Forty-eight (63%) completed the first follow-up at age 15 and 36 (47%) the second follow-up at age 18. Comprehensive exercise data were collected. Echocardiography with three-dimensional measurements and cardiopulmonary exercise testing were performed at all time points. The cohort was divided into active and former endurance athletes, with an eight hours of weekly endurance exercise cut-off at age 18. Results: The athletes underwent eccentric remodelling between ages 12 and 15, and concentric remodelling between ages 15 and 18. At age 18, the active endurance athletes had greater increases in inter-ventricular wall thickness (1.8 ± 1.4 Δmm vs 0.6 ± 1.0 Δmm, p < 0.05), left ventricular (LV) posterior wall thickness (1.6 ± 1.2 Δmm vs 0.8 ± 0.8 Δmm, p < 0.05), LV mass (63 ± 30 Δg vs 27 ± 21 Δg, p < 0.01), right ventricular (RV) end-diastolic area (3.4 ± 4.0 Δcm2 vs 0.6 ± 3.5Δ cm2, p < 0.05), RV end-systolic area (1.0 ± 2.3 Δcm2 vs –0.9 ± 2.0 Δcm2, p < 0.05) and left atrial volume (24 ± 21 ΔmL vs 6±10 ΔmL, p < 0.05) and had greater indexed maximal oxygen uptake (66.3 ± 7.4 mL/min/kg vs 57.1 ± 8.2 mL/min/kg, p < 0.01). There was no significant difference for LV volumes. Conclusion: This study finds a shift in the development of the young athlete’s heart. Between ages 12 and 15, the active endurance athletes underwent eccentric remodelling. This dynamic switched to concentric remodelling between ages 15 and 18.

• Chivulescu, Ana Monica; Lie, Øyvind Haugen; Popescu, Bogdan A.; Skulstad, Helge; Edvardsen, Thor; Jurcut, Ruxandra & Haugaa, Kristina (2020). High penetrance and similar disease progression in probands and in family members with arrhythmogenic cardiomyopathy. European Heart Journal.  ISSN 0195-668X.  41(14), s 1401- 1410 . doi: 10.1093/eurheartj/ehz570
• Corrado, Domenico; Perazzolo Marra, Martina; Zorzi, Alessandro; Beffagna, Giorgia; Cipriani, Alberto; Lazzari, Manuel De; Migliore, Federico; Pilichou, Kalliopi; Rampazzo, Alessandra; Rigato, Ilaria; Rizzo, Stefania; Thiene, Gaetano; Anastasakis, Aris; Asimaki, Angeliki; Bucciarelli-Ducci, Chiara; Haugaa, Kristina; Marchlinski, Francis E.; Mazzanti, Andrea; McKenna, William J.; Pantazis, Antonis; Pelliccia, Antonio; Schmied, Christian; Sharma, Sanjay; Wichter, Thomas; Bauce, Barbara & Basso, Cristina (2020). Diagnosis of arrhythmogenic cardiomyopathy: The Padua criteria. International Journal of Cardiology.  ISSN 0167-5273.  319, s 106- 114 . doi: 10.1016/j.ijcard.2020.06.005
• Corrado, Domenico; van Tintelen, Peter J.; McKenna, William J.; Hauer, Richard N.W.; Anastastakis, Aris; Asimaki, Angeliki; Basso, Cristina; Bauce, Barbara; Brunckhorst, Corinna; Bucciarelli-Ducci, Chiara; Duru, Firat; Elliott, Perry; Hamilton, Robert M.; Haugaa, Kristina; James, Cynthia A.; Judge, Daniel; Link, Mark S.; Marchlinski, Francis E.; Mazzanti, Andrea; Mestroni, Luisa; Pantazis, Antonis; Pelliccia, Antonio; Marra, Martina Perazzolo; Pilichou, Kalliopi; Platonov, Pyotr G.; Protonotarios, Alexandros; Rampazzo, Alessandra; Saffitz, Jeffry E.; Saguner, Ardan M.; Schmied, Christian; Sharma, Sanjay; Tandri, Hari; te Riele, Anneline S.J.M.; Thiene, Gaetano; Tsatsopoulou, Adalena; Zareba, Wojciech; Zorzi, Alessandro; Wichter, Thomas; Marcus, Frank I. & Calkins, Hugh (2020). Arrhythmogenic right ventricular cardiomyopathy: Evaluation of the current diagnostic criteria and differential diagnosis. European Heart Journal.  ISSN 0195-668X.  41(14), s 1414- 1427b . doi: 10.1093/eurheartj/ehz669
• Dweck, Mark R.; Bularga, Anda; Hahn, Rebecca T.; Bing, Rong; Lee, Kuan Ken; Chapman, Andrew R.; White, Audrey; Salvo, Giovanni Di; Sade, Leyla Elif; Pearce, Keith; Newby, David E.; Popescu, Bogdan A.; Donal, Erwan; Cosyns, Bernard; Edvardsen, Thor; Mills, Nicholas L. & Haugaa, Kristina (2020). Global evaluation of echocardiography in patients with COVID-19. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(9), s 949- 958 . doi: 10.1093/ehjci/jeaa178
• Edvardsen, Thor; Haugaa, Kristina; Petersen, Steffen E.; Gimelli, Alessia; Donal, Erwan; Maurer, Gerald; Popescu, Bogdan A. & Cosyns, Bernard (2020). The year 2019 in the European Heart Journal - Cardiovascular Imaging: Part i. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(11), s 1208- 1215 . doi: 10.1093/ehjci/jeaa259 Fulltekst i vitenarkiv.
• Hetland, Sveinung Arild; Vistnes, Maria; Haugaa, Kristina; Liland, Kristian Hovde; Olseng, Margareth & Edvardsen, Thor (2020). Obstructive sleep apnea versus central sleep apnea: prognosis in systolic heart failure. Cardiovascular Diagnosis and Therapy (CDT).  ISSN 2223-3652.  10(3), s 396- 404 . doi: 10.21037/cdt.2020.03.02
• Holte, Espen; Dweck, Mark R.; Marsan, Nina Ajmone; D'Andrea, Antonello; Manka, Robert; Stankovic, Ivan & Haugaa, Kristina (2020). EACVI survey on the evaluation of infective endocarditis. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(8), s 828- 832 . doi: 10.1093/ehjci/jeaa066 Fulltekst i vitenarkiv.
• Klæboe, Lars Gunnar; Brekke, Pål Haugar; Aaberge, Lars; Haugaa, Kristina & Edvardsen, Thor (2020). Impact of transcatheter aortic valve implantation on mechanical dispersion. Open heart.  ISSN 2053-3624.  7(1), s 1- 8 . doi: 10.1136/openhrt-2019-001199 Fulltekst i vitenarkiv.
• Lie, Øyvind Haugen & Haugaa, Kristina (2020). The super healthy atrial fibrillation conundrum. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(12), s 1384- 1385 . doi: 10.1093/ehjci/jeaa217 Fulltekst i vitenarkiv.
• Lie, Øyvind Haugen; Klæboe, Lars Gunnar; Dejgaard, Lars; Skjølsvik, Eystein Theodor Ek; Grimsmo, Jostein; Bosse, Gerhard; Hopp, Einar; Edvardsen, Thor & Haugaa, Kristina (2020). Cardiac phenotypes and markers of adverse outcome in elite athletes with ventricular arrhythmias. JACC Cardiovascular Imaging.  ISSN 1936-878X.  s 148- 158 . doi: 10.1016/j.jcmg.2020.07.039 Fulltekst i vitenarkiv.
• Lieve, Krystien V.V.; Dusi, Veronica; Van Der Werf, Christian; Bos, J. Martijn; Lane, Conor M.; Stokke, Mathis Korseberg; Roston, Thomas M.; Djupsjöbacka, Aurora; Wada, Yuko; Denjoy, Isabelle; Bundgaard, Henning; Noguer, Ferran Roses I.; Semsarian, Christopher; Robyns, Tomas; Hofman, Nynke; Tanck, Michael W.; Van Den Berg, Maarten P.; Kammeraad, Janneke A.E.; Krahn, Andrew D.; Clur, Sally Ann; Sacher, Frederic; Till, Jan; Skinner, Jonathan R.; Tfelt-Hansen, Jacob; Probst, Vincent; Leenhardt, Antoine; Horie, Minoru; Swan, Heikki; Roberts, Jason D.; Sanatani, Shubhayan; Haugaa, Kristina; Schwartz, Peter J.; Ackerman, Michael J. & Wilde, Arthur A.M. (2020). Heart Rate Recovery after Exercise Is Associated with Arrhythmic Events in Patients with Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation: Arrhythmia and Electrophysiology.  ISSN 1941-3149.  13(3) . doi: 10.1161/CIRCEP.119.007471
• Michalski, Blazej; Dweck, Mark R.; Marsan, Nina Ajmone; Cameli, Matteo; D'Andrea, Antonello; Carvalho, Ricardo Fontes; Holte, Espen; Podlesnikar, Tomaz; Manka, Robert & Haugaa, Kristina (2020). The evaluation of aortic stenosis, how the new guidelines are implemented across Europe: A survey by EACVI. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(4), s 357- 362 . doi: 10.1093/ehjci/jeaa009
• Otterstad, Jan Erik; Norum, Ingvild Billehaug; Ruddox, Vidar; Bendz, Bjørn; Haugaa, Kristina & Edvardsen, Thor (2020). The impact of semi-automatic versus manually adjusted assessment of global longitudinal strain in post-myocardial infarction patients. The International Journal of Cardiovascular Imaging.  ISSN 1569-5794.  36(7), s 1283- 1290 . doi: 10.1007/s10554-020-01826-4 Fulltekst i vitenarkiv. Vis sammendrag

  There are unresolved questions related to the proper use of editing the region of interest (ROI) for measurements of global longitudinal strain (GLS). The purpose of the present study was to compare the semi-automatic default GLS value by the vendor's software with manually adjusted GLS and test the impact on GLS measures with different ROI widths. We selected 25 patients post myocardial infarction treated with PCI who had excellent echocardiographic recordings after 2-5 days and 3 months. The different GLS values were assessed from these 50 analyses in three steps. The semi-automatically GLS by default ROIs was compared with manually adjusted ROIs widths selected by an expert and then with manual adjustments, but with fixed ROIs being narrow, medium and wide. Their mean age was 64 (+/- 12) years, 52% had ST elevation MI and mean LVEF was 52 (+/- 4)%. Mean default GLS was - 15.3 (+/- 2.5)% with the widest ROI level selected semi-automatically in 78% of all widths. The mean expert GLS with manually adjusted ROI was - 14.7 (+/- 2.4)%, and the medium ROI level was selected by the expert in 85% of all examinations. The mean adjusted GLS, but with fixed ROIs widths was - 15.0 (+/- 2.5%)% with narrow ROI, - 14.7 (+/- 2.6)% with medium and - 13.5 (+/- 2.3)% with wide ROI width (p < 0.001 vs. default GLS). The Intra Class Coefficient Correlation between default and manually adjusted expert GLS was 0.93 (p < 0.001). The difference between the default and the manually adjusted expert GLS was neglectable. These findings may represent a simplification of the assessment of GLS that might increase its use in clinical practice. The GLS measurements with a fixed wide ROIs were significantly different from the expert measurements and indicate that a wide ROI should be avoided

• Platonov, Pyotr G.; Castrini, Anna Isotta; Svensson, Anneli; Christiansen, Morten K.; Gilljam, Thomas; Bundgaard, Henning; Madsen, Trine; Heliö, Tiina; Christensen, Alex H.; Åström, Meriam Aneq; Carlson, Jonas; Edvardsen, Thor; Jensen, Henrik K.; Haugaa, Kristina & Svendsen, Jesper H. (2020). Pregnancies, ventricular arrhythmias, and substrate progression in women with arrhythmogenic right ventricular cardiomyopathy in the Nordic ARVC Registry. Europace.  ISSN 1099-5129.  22(12), s 1873- 1879 . doi: 10.1093/europace/euaa136
• Ross, Stian Balnagown; Nestaas, Eirik; Kongsgård, Erik; Odland, Hans Henrik; Håland, Trine Synnøve Fink; Hopp, Einar; Haugaa, Kristina & Edvardsen, Thor (2020). Septal contraction predicts acute haemodynamic improvement and paced QRS width reduction in cardiac resynchronization therapy. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(8), s 845- 852 . doi: 10.1093/ehjci/jez315 Vis sammendrag

  Three distinct septal contraction patterns typical for left bundle branch block may be assessed using echocardiography in heart failure patients scheduled for cardiac resynchronization therapy (CRT). The aim of this study was to explore the association between these septal contraction patterns and the acute haemodynamic and electrical response to biventricular pacing (BIVP) in patients undergoing CRT implantation. Thirty-eight CRT candidates underwent speckle tracking echocardiography prior to device implantation. The patients were divided into two groups based on whether their septal contraction pattern was indicative of dyssynchrony (premature septal contraction followed by various amount of stretch) or not (normally timed septal contraction with minimal stretch). CRT implantation was performed under invasive left ventricular (LV) pressure monitoring and we defined acute CRT response as ≥10% increase in LV dP/dtmax. End-diastolic pressure (EDP) and QRS width served as a diastolic and electrical parameter, respectively. LV dP/dtmax improved under BIVP (737 ± 177 mmHg/s vs. 838 ± 199 mmHg/s, P < 0.001) and 26 patients (68%) were defined as acute CRT responders. Patients with premature septal contraction (n = 27) experienced acute improvement in systolic (ΔdP/dtmax: 18.3 ± 8.9%, P < 0.001), diastolic (ΔEDP: −30.6 ± 29.9%, P < 0.001) and electrical (ΔQRS width: −23.3 ± 13.2%, P < 0.001) parameters. No improvement under BIVP was observed in patients (n = 11) with normally timed septal contraction (ΔdP/dtmax: 4.0 ± 7.8%, P = 0.12; ΔEDP: −8.8 ± 38.4%, P = 0.47 and ΔQRS width: −0.9 ± 11.4%, P = 0.79).   Septal contraction patterns are an excellent predictor of acute CRT response. Only patients with premature septal contraction experienced acute systolic, diastolic, and electrical improvement under BIVP.

• Skjølsvik, Eystein Theodor Ek; Hasselberg, Nina Eide; Dejgaard, Lars; Lien, Øyvind Haugan; Andersen, Kjell; Holm, Torbjørn; Edvardsen, Thor & Haugaa, Kristina (2020). Exercise is Associated With Impaired Left Ventricular Systolic Function in Patients With Lamin A/C Genotype. Journal of the American Heart Association (JAHA).  ISSN 2047-9980.  9(2) . doi: 10.1161/JAHA.119.012937 Fulltekst i vitenarkiv. Vis sammendrag

  Background Lamin A/C cardiomyopathy is a malignant and highly penetrant inheritable cardiomyopathy. Competitive sports have been associated with adverse events in these patients, but data on recreational exercise are lacking. We aimed to explore associations between exercise exposure and disease severity in patients with lamin A/C genotype. Methods and Results Lamin A/C genotype positive patients answered a questionnaire on exercise habits from age 7 years until genetic diagnosis. We recorded exercise hours >3 metabolic equivalents and calculated cumulative lifetime exercise. Patients were grouped in active or sedate based on lifetime exercise hours above or below median. We performed echocardiography, 12‐lead ECG, Holter monitoring, and biomarkers including NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide). We defined left ventricular ejection fraction <45% as a clinically significant impairment of left ventricular function. We included 69 patients (age 42±14 years, 41% probands, 46% women) with median lifetime exercise 4160 (interquartile range 1041–6924) hours. Active patients were more frequently probands (53% versus 29%, P=0.04), had lower left ventricular ejection fraction (43±13% versus 51±11%, P=0.006), and higher NT‐proBNP (78 [interquartile range 32–219] pmol/L versus 30 [interquartile range 13–64] pmol/L, P=0.03) compared with sedate, while age did not differ (45±13 years versus 40±16 years, P=0.16). The decrease in left ventricular ejection fraction per tertile increment in lifetime exercise was 4% (95% CI −7% to −0.4%, P=0.03), adjusted for age and sex and accounting for dependence within families. Left ventricular ejection fraction <45% was observed at a younger age in active patients (log rank P=0.007). Conclusions Active lamin A/C patients had worse systolic function compared with sedate which occurred at younger age. Our findings may improve exercise recommendations in patients with lamin A/C.

• Skulstad, Helge; Cosyns, Bernard; Popescu, Bogdan A.; Galderisi, Maurizio; Salvo, Giovanni Di; Donal, Erwan; Petersen, Steffen; Gimelli, Alessia; Haugaa, Kristina; Muraru, Denisa; Almeida, Ana G.; Schulz-Menger, Jeanette; Dweck, Mark R.; Pontone, Gianluca; Sade, Leyla Elif; Gerber, Bernhard L.; Maurovich-Horvat, Pál; Bharucha, Tara; Cameli, Matteo; Magne, Julien; Westwood, Mark; Maurer, Gerald & Edvardsen, Thor (2020). COVID-19 pandemic and cardiac imaging: EACVI recommendations on precautions, indications, prioritization, and protection for patients and healthcare personnel. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(6), s 592- 598 . doi: 10.1093/ehjci/jeaa072
• Smistad, Erik; Østvik, Andreas; Salte, Ivar Mjåland; Melichova, Daniela; Nguyen, Thuy Mi; Haugaa, Kristina; Brunvand, Harald; Edvardsen, Thor; Leclerc, Sarah; Bernard, Olivier; Grenne, Bjørnar & Løvstakken, Lasse (2020). Real-Time Automatic Ejection Fraction and Foreshortening Detection Using Deep Learning. IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.  ISSN 0885-3010.  67(12), s 2595- 2604 . doi: 10.1109/TUFFC.2020.2981037 Fulltekst i vitenarkiv. Vis sammendrag

  Volume and ejection fraction (EF) measurements of the left ventricle (LV) in 2-D echocardiography are associated with a high uncertainty not only due to interobserver variability of the manual measurement, but also due to ultrasound acquisition errors such as apical foreshortening. In this work, a real-time and fully automated EF measurement and foreshortening detection method is proposed. The method uses several deep learning components, such as view classification, cardiac cycle timing, segmentation and landmark extraction, to measure the amount of foreshortening, LV volume, and EF. A data set of 500 patients from an outpatient clinic was used to train the deep neural networks, while a separate data set of 100 patients from another clinic was used for evaluation, where LV volume and EF were measured by an expert using clinical protocols and software. A quantitative analysis using 3-D ultrasound showed that EF is considerably affected by apical foreshortening, and that the proposed method can detect and quantify the amount of apical foreshortening. The bias and standard deviation of the automatic EF measurements were -3.6 ± 8.1%, while the mean absolute difference was measured at 7.2% which are all within the interobserver variability and comparable with related studies. The proposed real-time pipeline allows for a continuous acquisition and measurement workflow without user interaction, and has the potential to significantly reduce the time spent on the analysis and measurement error due to foreshortening, while providing quantitative volume measurements in the everyday echo lab.

• Stancovic, Ivan; Dweck, Marc; Marsan, Nina Ajmone; Bergler-Klein, Jutta; Holte, Espen; Manka, Robert; Schulz-Menger, Jeanette; Sitges, Marta & Haugaa, Kristina (2020). The EACVI survey on cardiac imaging in cardio-oncology. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404. . doi: 10.1093/ehjci/jeaa111 Fulltekst i vitenarkiv. Vis sammendrag

  Early and late cardiovascular (CV) toxicities related to many cancer treatments may complicate the clinical course of patients, offsetting therapeutic benefits, and altering prognosis. The early detection, monitoring, and treatment of cardiotoxicity have therefore become essential parts of cancer patient care. CV imaging is a cornerstone of every cardio-oncology unit, but its use may vary across Europe because of the non-uniform availability of advanced imaging techniques and differences in the organization and logistics of cardio-oncology services. The purpose of this EACVI survey in cardio-oncology is to obtain real-world data on the current usage of cardiac imaging in cancer patients. Data from 104 centres and 35 different countries confirmed that cardiac imaging plays a pivotal role in the detection and monitoring of cardiac toxicity in oncology patients in Europe and beyond. However, it also revealed gaps between guidelines recommendations and everyday clinical practice, highlighting some of the challenges that need to be overcome in this rapidly advancing field.

• Stokke, Mathis Korseberg; Castrini, Anna Isotta; Aneq, Meriam Åström; Jensen, Henrik K.; Madsen, Trine; Hansen, Jim; Bundgaard, Henning; Gilljam, Thomas; Platonov, Pyotr G.; Svendsen, Jesper Hastrup; Edvardsen, Thor & Haugaa, Kristina (2020). Absence of ECG Task Force Criteria does not rule out structural changes in genotype positive ARVC patients. International Journal of Cardiology.  ISSN 0167-5273. . doi: 10.1016/j.ijcard.2020.05.095 Fulltekst i vitenarkiv.
• Voigt, Jens-Uwe; Malaescu, Georgiana-Gratiela; Haugaa, Kristina & Badano, Luigi P. (2020). How to do la strain. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  21(7), s 715- 717 . doi: 10.1093/ehjci/jeaa091
• Babic, Aleksandar; Odland, Hans Henrik; Lyseggen, Erik; Holm, Torbjørn; Ross, Stian Balnagown; Hopp, Einar; Haugaa, Kristina; Kongsgård, Erik; Edvardsen, Thor; Olivier, Gerard & Samset, Eigil (2019). An image fusion tool for echo‐guided left ventricular lead placement in cardiac resynchronization therapy: Performance and workflow integration analysis. Echocardiography.  ISSN 0742-2822.  36(10), s 1834- 1845 . doi: 10.1111/echo.14483 Fulltekst i vitenarkiv.
• Baturova, Maria A; Haugaa, Kristina; Jensen, Henrik K; Svensson, Anneli; Gilljam, Thomas; Bundgaard, Henning; Madsen, Trine; Hansen, Jim; Chivulescu, Ana Monica; Christiansen, Morten Krogh; Carlson, Jonas; Edvardsen, Thor; Svendsen, Jesper H. & Platonov, Pyotr G (2019). Atrial fibrillation as a clinical characteristic of arrhythmogenic right ventricular cardiomyopathy: Experience from the Nordic ARVC Registry. International Journal of Cardiology.  ISSN 0167-5273.  (298), s 39- 43 . doi: 10.1016/j.ijcard.2019.07.086 Fulltekst i vitenarkiv. Vis sammendrag

  Abstract BACKGROUND: Recent studies in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients have drawn attention to atrial fibrillation (AF) as an arrhythmic manifestation of ARVC and as an indicator of atrial involvement in the disease progression. We aimed to assess the prevalence of AF in the Scandinavian cohort of ARVC patients and to evaluate its association with disease clinical manifestations. METHODS: Study sample comprised of 293 definite ARVC patients by 2010 Task Force criteria (TFC2010) and 141 genotype-positive family members (total n = 434, 43% females, median age at ARVC diagnosis 41 years [interquartile range (IQR) 28-52 years]). ARVC diagnostic score was calculated as the sum of major (2 points) and minor (1 point) criteria in all categories of the TFC2010. RESULTS: AF was diagnosed in 42 patients (10%): in 41 patients with definite ARVC diagnosis (14%) vs in one genotype-positive family member (1%), p < 0.001. The median age at AF onset was 51 (IQR 38-58) years. The prevalence of AF was related to the ARVC diagnostic score: it significantly increased starting with the diagnostic score 4 (2% in those with score 3 vs 13% in those with score 4, p = 0.023) and increased further with increased diagnostic score (Somer's d value is 0.074, p < 0.001). CONCLUSION: AF is seen in 14% of definite ARVC patients and is related to the severity of disease phenotype thus suggesting AF being an arrhythmic manifestation of this cardiomyopathy indicating atrial myocardial involvement in the disease progression.

• Bjerring, Anders W.; Landgraff, Hege Elisabeth W.; Stokke, Thomas Muri; Murbræch, Klaus; Leirstein, Svein; Aaeng, Anette; Brun, Henrik; Haugaa, Kristina; Hallén, Jostein; Edvardsen, Thor & Sarvari, Sebastian (2019). The developing athlete's heart: a cohort study in young athletes transitioning through adolescence. European Journal of Preventive Cardiology (EJPC).  ISSN 2047-4873.  s 1- 8 . doi: 10.1177/2047487319862061 Fulltekst i vitenarkiv. Vis sammendrag

  Background Athlete's heart is a term used to describe physiological changes in the hearts of athletes, but its early development has not been described in longitudinal studies. This study aims to improve our understanding of the effects of endurance training on the developing heart. Methods Cardiac morphology and function in 48 cross-country skiers were assessed at age 12 years (12.1 ± 0.2 years) and then again at age 15 years (15.3 ± 0.3 years). Echocardiography was performed in all subjects including two-dimensional speckle-tracking strain echocardiography and three-dimensional echocardiography. All participants underwent cardiopulmonary exercise testing at both ages 12 and 15 years to assess maximal oxygen uptake and exercise capacity. Results Thirty-one (65%) were still active endurance athletes at age 15 years and 17 (35%) were not. The active endurance athletes had greater indexed maximal oxygen uptake (62 ± 8 vs. 57 ± 6 mL/kg/min, P < 0.05) at follow-up. There were no differences in cardiac morphology at baseline. At follow-up the active endurance athletes had greater three-dimensional indexed left ventricular end-diastolic (84 ± 11 mL/m2 vs. 79 ± 10 mL/m2, P < 0.05) and end-systolic volumes (36 ± 6 mL/m2 vs. 32 ± 3 mL/m2, P < 0.05). Relative wall thickness fell in the active endurance athletes, but not in those who had quit (–0.05 ΔmL/m2 vs. 0.00 mL/m2, P = 0.01). Four active endurance athletes had relative wall thickness above the upper reference values at baseline; all had normalised at follow-up. Conclusion After an initial concentric remodelling in the pre-adolescent athletes, those who continued their endurance training developed eccentric changes with chamber dilatation and little change in wall thickness. Those who ceased endurance training maintained a comparable wall thickness, but did not develop chamber dilatation.

• Cadrin-Tourigny, Julia; Bosman, Laurens P.; Nozza, Anna; Wang, Weijia; Tadros, Rafik; Bhonsale, Aditya; Bourfiss, Mimount; Fortier, Annik; Lie, Øyvind Haugen; Saguner, Ardan M.; Svensson, Anneli; Andorin, Antoine; Tichnell, Crystal; Murray, Brittney; Zeppenfeld, Katja; van den Berg, Maarten P.; Asselbergs, Folkert W.; Wilde, Arthur A.M.; Krahn, Andrew D.; Talajic, Mario; Rivard, Lena; Chelko, Stephen; Zimmerman, Stefan L.; Kamel, Ihab R.; Crosson, Jane E.; Judge, Daniel P.; Yap, Sing-Chien; van der Heijden, Jeroen F.; Tandri, Harikrishna; Jongbloed, Jan D.H.; Guertin, Marie-Claude; van Tintelen, J. Peter; Platonov, Pyotr G.; Duru, Firat; Haugaa, Kristina; Khairy, Paul; Hauer, Richard N.W.; Calkins, Hugh; te Riele, Anneline S.J.M. & James, Cynthia A. (2019). A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy. European Heart Journal.  ISSN 0195-668X.  40(23), s 1850- 1858 . doi: 10.1093/eurheartj/ehz103
• Cameli, Matteo; Marsan, Nina Ajmone; D'Andrea, Antonello; Dweck, Mark R.; Fontes-Carvalho, Ricardo; Manka, Robert; Michalski, Blazej; Podlesnikar, Tomaz; Sitges, Marta; Popescu, Bogdan A.; Edvardsen, Thor; Fox, Kevin F. & Haugaa, Kristina (2019). EACVI survey on multimodality training in ESC countries. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(12), s 1332- 1336 . doi: 10.1093/ehjci/jez200 Fulltekst i vitenarkiv.
• Castrini, Anna Isotta; Lie, Øyvind Haugen; Leren, Ida Skrinde; Estensen, Mette-Elise; Stokke, Mathis Korseberg; Klæboe, Lars Gunnar; Edvardsen, Thor & Haugaa, Kristina (2019). Number of pregnancies and subsequent phenotype in a cross-sectional cohort of women with arrhythmogenic cardiomyopathy. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(2), s 192- 198 . doi: 10.1093/ehjci/jey061 Fulltekst i vitenarkiv.
• Christiansen, Morten K; Haugaa, Kristina; Svensson, Anneli; Gilljam, Thomas; Madsen, Trine; Hansen, Jim; Holst, Anders G; Bundgaard, Henning; Edvardsen, Thor; Svendsen, Jesper H.; Platonov, Pyotr G & Jensen, Henrik K (2019). Incidence, Predictors, and Success of Ventricular Tachycardia Catheter Ablation in Arrhythmogenic Right Ventricular Cardiomyopathy (from the Nordic ARVC Registry). American Journal of Cardiology.  ISSN 0002-9149.  125, s 803- 811 . doi: 10.1016/j.amjcard.2019.11.026 Fulltekst i vitenarkiv.
• Conte, Giulio; Belhassen, Bernard; Lambiase, Pier; Ciconte, Giuseppe; de Asmundis, Carlo; Arbelo, Elena; Schaer, Beat; Frontera, Antonio; Burri, Haran; Calo, Leonardo; Letsas, Kostantinos P.; Leyva, Francisco; Porter, Bradley; Saenen, Johan; Zacà, Valerio; Berne, Paola; Ammann, Peter; Zardini, Marco; Luani, Blerim; Rordorf, Roberto; Sarquella Brugada, Georgia; Medeiros-Domingo, Argelia; Geller, Johann-Christoph; de Potter, Tom; Stokke, Mathis Korseberg; Márquez, Manlio F.; Michowitz, Yoav; Honarbakhsh, Shohreh; Conti, Manuel; Sticherling, Christian; Martino, Annamaria; Zegard, Abbasin; Özkartal, Tardu; Caputo, Maria Luce; Regoli, François; Braun-Dullaeus, Rüdiger C.; Notarangelo, Francesca; Moccetti, Tiziano; Casu, Gavino; Rinaldi, Christopher A.; Levinstein, Moises; Haugaa, Kristina; Derval, Nicolas; Klersy, Catherine; Curti, Moreno; Pappone, Carlo; Heidbuchel, Hein; Brugada, Josép; Haïssaguerre, Michel; Brugada, Pedro & Auricchio, Angelo (2019). Out-of-hospital cardiac arrest due to idiopathic ventricular fibrillation in patients with normal electrocardiograms: Results from a multicentre long-term registry. Europace.  ISSN 1099-5129.  21(11), s 1670- 1677 . doi: 10.1093/europace/euz221
• Cosyns, Bernard; Haugaa, Kristina; Gerber, Bernhard L.; Gimelli, Alessia; Donal, Erwan; Maurer, Gerald & Edvardsen, Thor (2019). The year 2018 in the European Heart Journal - Cardiovascular Imaging: Part II. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(12), s 1337- 1344 . doi: 10.1093/ehjci/jez218
• Cuneo, Bettina F.; Kaizer, Alexander M.; Clur, Sally Ann; Swan, Heikki; Herberg, Ulrike; Winbo, Annika; Rydberg, Annika; Haugaa, Kristina; Etheridge, Susan; Ackerman, Michael J.; Dagradi, Federica; Killen, Stacy A.S.; Wacker-Gussmann, Annette; Benson, D. Woodrow; Wilde, Arthur Arnold Maria; Pan, Zhaoxing; Lam, Aimee; Spazzolini, Carla; Horigome, Hitoshi & Schwartz, Peter J. (2019). Mothers with long QT syndrome are at increased risk for fetal death: findings from a multicenter international study. American Journal of Obstetrics and Gynecology.  ISSN 0002-9378.  222(3), s 263.e1- 263.e11 . doi: 10.1016/j.ajog.2019.09.004
• Edvardsen, Thor; Haugaa, Kristina; Petersen, Steffen E.; Gimelli, Alessia; Donal, Erwan; Maurer, Gerald; Popescu, Bogdan A. & Cosyns, Bernard (2019). The year 2018 in the European Heart Journal - Cardiovascular Imaging: Part I. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(8), s 858- 865 . doi: 10.1093/ehjci/jez133 Fulltekst i vitenarkiv.
• Gibbs, Charlotte Christine; Thalamus, Jacob; Kristoffersen, Doris Tove; Svendsen, Martin Veel; Holla, Øystein Lunde; Heldal, Kristian; Haugaa, Kristina & Hysing, Jan (2019). QT prolongation predicts short-term mortality independent of comorbidity. Europace.  ISSN 1099-5129.  21(8), s 1254- 1260 . doi: 10.1093/europace/euz058 Fulltekst i vitenarkiv.
• Haugaa, Kristina & Leren, Ida Skrinde (2019). Prevalence, clinical presentation, and management of channelopathies and cardiomyopathies, long QT syndrome, Brugada syndrome, arrhythmogenic cardiomyopathy, and hypertrophic cardiomyopathy. Current Cardiovascular Risk Reports.  ISSN 1932-9520.  13:16(7), s 1- 7 . doi: 10.1007/s12170-019-0612-2
• Haugaa, Kristina & Lie, Øyvind Haugen (2019). Cardiac amyloidosis: can imaging shed light on mechanisms and prognosis?. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(5), s 500- 501 . doi: 10.1093/ehjci/jez009 Fulltekst i vitenarkiv.
• Haugaa, Kristina; Marsan, Nina Ajmone; Cameli, Matteo; D'Andrea, Antonello; Dweck, Mark R.; Carvalho, Ricardo Fontes; Holte, Espen; Manka, Robert; Michalski, Blazej; Podlesnikar, Tomaz; Popescu, Bogdan A.; Schulz-Menger, Jeanette; Sitges, Marta; Stankovic, Ivan; Maurer, Gerald & Edvardsen, Thor (2019). Criteria for surveys: from the European Association of Cardiovascular Imaging Scientific Initiatives Committee. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(9), s 963- 966 . doi: 10.1093/ehjci/jez193 Fulltekst i vitenarkiv.
• Kawakami, Hiroshi; Nerlekar, Nitesh; Haugaa, Kristina; Edvardsen, Thor & Marwick, Thomas H. (2019). Prediction of Ventricular Arrhythmias With Left Ventricular Mechanical Dispersion: A Systematic Review and Meta-Analysis. JACC Cardiovascular Imaging.  ISSN 1936-878X.  13(2), s 562- 572 . doi: 10.1016/j.jcmg.2019.03.025
• Klæboe, Lars Gunnar; Brekke, Pål Haugar; Lie, Øyvind Haugen; Aaberge, Lars; Haugaa, Kristina & Edvardsen, Thor (2019). Classical mechanical dyssynchrony is rare in transcatheter aortic valve implantation-induced left bundle branch block. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(3), s 271- 278 . doi: 10.1093/ehjci/jey127 Fulltekst i vitenarkiv.
• Kvisvik, Brede Alexander; Aagaard, Erika Nerdrum; Mørkrid, Lars; Røsjø, Helge; Lyngbakken, Magnus; Smedsrud, Marit Kristine; Eek, Christian; Bendz, Bjørn; Haugaa, Kristina; Edvardsen, Thor & Gravning, Jørgen A. (2019). Mechanical dispersion as a marker of left ventricular dysfunction and prognosis in stable coronary artery disease. The International Journal of Cardiovascular Imaging.  ISSN 1569-5794.  35, s 1265- 1275 . doi: 10.1007/s10554-019-01583-z Fulltekst i vitenarkiv.
• Magne, Julien; Bharucha, Tara; Bucciarelli-Ducci, Chiara; Dahl, Jordi S.; Gimelli, Alessia; Haugaa, Kristina; Muraru, Denisa; Donal, Erwan; Edvardsen, Thor & Popescu, Bogdan A. (2019). EuroEcho-imaging 2018: highlights. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(5), s 489- 497 . doi: 10.1093/ehjci/jez042
• Platonov, Pyotr G.; Haugaa, Kristina; Bundgaard, Henning; Svensson, Anneli; Gilljam, Thomas; Hansen, Jim; Madsen, Trine; Holst, Anders Gaarsdal; Carlson, Jonas; Lie, Øyvind Haugen; Kvistholm Jensen, Morten; Edvardsen, Thor; Jensen, Henrik K. & Svendsen, Jesper H. (2019). Primary prevention of sudden cardiac death with implantable cardioverter-defibrillator therapy in patients with arrhythmogenic right ventricular cardiomyopathy. American Journal of Cardiology.  ISSN 0002-9149.  123(7), s 1156- 1162 . doi: 10.1016/j.amjcard.2018.12.049 Fulltekst i vitenarkiv.
• Rootwelt, Christine; Lie, Øyvind Haugen; Dejgaard, Lars; Chivulescu, Ana Monica; Leren, Ida Skrinde; Edvardsen, Thor & Haugaa, Kristina (2019). Life-threatening arrhythmic presentation in patients with arrhythmogenic cardiomyopathy before and after entering the genomic era; a two-decade experience from a large volume center. International Journal of Cardiology.  ISSN 0167-5273.  (279), s 79- 83 . doi: 10.1016/j.ijcard.2018.12.066 Fulltekst i vitenarkiv.
• Scheirlynck, Esther Steffie; Dejgaard, Lars; Skjølsvik, Eystein Theodor Ek; Lie, Øyvind Haugen; Motoc, Andreea; Hopp, Einar; Tanaka, Kaoru; Ueland, Thor; Ribe, Margareth; Collet, Carlos; Edvardsen, Thor; Droogmans, Steven; Cosyns, Bernard & Haugaa, Kristina (2019). Increased levels of sST2 in patients with mitral annulus disjunction and ventricular arrhythmias. Open heart.  ISSN 2053-3624.  6:e001016(1), s 1- 8 . doi: 10.1136/openhrt-2019-001016 Fulltekst i vitenarkiv.
• Van Der Werf, Christian; Lieve, Krystien V; Bos, J. Martijn; Lane, Conor M; Denjoy, Isabelle; Roses-Noguer, Ferran; Aiba, Takeshi; Wada, Yuko; Ingles, Jodie; Leren, Ida Skrinde; Rudic, Boris; Schwartz, Peter J; Maltret, Alice; Sacher, Frederic; Skinner, Jonathan R.; Krahn, Andrew D.; Roston, Thomas M; Tfelt-Hansen, Jacob; Swan, Heikki; Robyns, Tomas; Ohno, Seiko; Roberts, Jason; Van Den Berg, Maarten P; Kammeraad, Janneke A; Probst, Vincent; Kannankeril, Prince J; Blom, Nico A; Behr, Elijah R; Borggrefe, Martin; Haugaa, Kristina; Semsarian, Christopher; Horie, Minoru; Shimizu, Wataru; Till, Janice A; Leenhardt, Antoine; Ackerman, Michael J & Wilde, Arthur AM (2019). Implantable cardioverter-defibrillators in previously undiagnosed patients with catecholaminergic polymorphic ventricular tachycardia resuscitated from sudden cardiac arrest. European Heart Journal.  ISSN 0195-668X.  40(35), s 2953- 2961 . doi: 10.1093/eurheartj/ehz309
• Bjerring, Anders W.; Landgraff, Hege Elisabeth W.; Leirstein, Svein; Aaeng, Anette; Ansari, Hamza; Saberniak, Jørg; Murbræch, Klaus; Brun, Henrik; Stokke, Thomas Muri; Haugaa, Kristina; Hallén, Jostein; Edvardsen, Thor & Sarvari, Sebastian (2018). Morphological changes and myocardial function assessed by traditional and novel echocardiographic methods in preadolescent athlete?s heart. European Journal of Preventive Cardiology (EJPC).  ISSN 2047-4873.  25(9), s 1000- 1007 . doi: 10.1177/2047487318776079 Vis sammendrag

  Background: Athlete’s heart is a term used to describe the morphological and functional changes in the hearts of athletes. Recent studies suggest that these changes may occur even in preadolescent athletes. This study aims to improve our understanding of the changes occurring in the preadolescent athlete’s heart. Design and methods: Cardiac morphology and function in 76 preadolescent cross-country skiers (aged 12.1 ± 0.2 years) were compared with 25 age-matched non-competing preadolescents. Echocardiography was performed in all subjects, including 2D speckle-tracking strain echocardiography and 3D echocardiography. All participants underwent cardiopulmonary exercise testing to assess oxygen uptake and exercise capacity. Results: Athletes had greater indexed VO2 max (62 ± 7 vs. 44 ± 5 mL/kg per min, p < 0.001), indexed left ventricular end-diastolic volume (79 ± 7 vs. 68 ± 7 mL/m2, p < 0.001), left ventricular mass (69 ± 12 vs. 57 ± 13 g/m2, p < 0.001), indexed right ventricular basal diameter (28.3 ± 3.0 vs. 25.4 ± 3.5 mm/m2, p < 0.001) and right atrial area (10.6 ± 1.4 vs. 9.7 ± 1.2 cm2/m2, p < 0.01). There was no difference in left ventricular ejection fraction, global longitudinal strain, and global circumferential strain and right ventricular fractional area change between the groups. Controls had higher right ventricular global longitudinal strain (−28.1 ± 3.5 vs. −31.1 ± 3.3%, p < 0.01). VO2 max was highly correlated to left ventricular end-diastolic volume (r = 0.76, p < 0.001). Conclusion: Athletes had greater left ventricular mass and greater left and right ventricular chamber dimensions compared with controls, while left ventricular function did not differ. Interestingly, right ventricular deformation was significantly lower compared with controls. This supports the notion that there is physiological, adaptive remodelling in preadolescent athlete’s heart.

• Boveda, Serge; Lenarczyk, Radosław; Haugaa, Kristina; Iliodromitis, Konstantinos; Finlay, Malcolm; Lane, Deirdre; Prinzen, Frits W. & Dagres, Nikolaos (2018). Use of leadless pacemakers in Europe: Results of the European Heart Rhythm Association survey. Europace.  ISSN 1099-5129.  20(3), s 555- 559 . doi: 10.1093/europace/eux381
• Chivulescu, Monica; Haugaa, Kristina; Lie, Øyvind Haugen; Edvardsen, Thor; Ginghină, Carmen; Popescu, Bogdan A. & Jurcut, Ruxandra (2018). Right ventricular remodeling in athletes and in arrhythmogenic cardiomyopathy. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  52(1), s 13- 19 . doi: 10.1080/14017431.2017.1416158
• Danielsen, Tore Kristian; Manotheepan, Ravinea; Sadredini, Mani; Leren, Ida Skrinde; Edwards, Andrew; Vincent, Kevin P.; Lehnart, Stephan .; Sejersted, Ole M; Sjaastad, Ivar; Haugaa, Kristina & Stokke, Mathis Korseberg (2018). Arrhythmia initiation in catecholaminergic polymorphic ventricular tachycardia type 1 depends on both heart rate and sympathetic stimulation. PLOS ONE.  ISSN 1932-6203.  13:e0207100(11), s 1- 21 . doi: 10.1371/journal.pone.0207100 Fulltekst i vitenarkiv.
• Dejgaard, Lars; Håland, Trine Synnøve Fink; Lie, Øyvind Haugen; Ribe, Margareth; Bjune, Thea; Leren, Ida Skrinde; Berge, Knut Erik; Edvardsen, Thor & Haugaa, Kristina (2018). Vigorous exercise in patients with hypertrophic cardiomyopathy. International Journal of Cardiology.  ISSN 0167-5273.  250, s 157- 163 . doi: 10.1016/j.ijcard.2017.07.015 Fulltekst i vitenarkiv.
• Dejgaard, Lars; Skjølsvik, Eystein Theodor Ek; Lie, Øyvind Haugen; Ribe, Margareth; Stokke, Mathis Korseberg; Hegbom, Finn; Scheirlynck, Esther Steffie; Gjertsen, Erik; Andresen, Kristoffer; Helle-Valle, Thomas Michael; Hopp, Einar; Edvardsen, Thor & Haugaa, Kristina (2018). The Mitral Annulus Disjunction Arrhythmic Syndrome. Journal of the American College of Cardiology.  ISSN 0735-1097.  72(14), s 1600- 1609 . doi: 10.1016/j.jacc.2018.07.070 Fulltekst i vitenarkiv.
• Delgado, Victoria; Cardim, Nuno; Cosyns, Bernard; Donal, Erwan; Flachskampf, Frank; Galderisi, Maurizio; Gerber, Bernhard; Gimelli, Alessia; Haugaa, Kristina; Kaufmann, Philipp A.; Lancellotti, Patrizio; Magne, Julien; Masci, Pier Giorgio; Muraru, Denisa; Habib, Gilbert; Edvardsen, Thor & Popescu, Bogdan A. (2018). Criteria for recommendation, expert consensus, and appropriateness criteria papers: Update from the European Association of Cardiovascular Imaging Scientific Documents Committee. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  19(8), s 835- 837 . doi: 10.1093/ehjci/jey079
• Edvardsen, Thor; Haugaa, Kristina; Gerber, Bernhard L.; Maurovich-Horvat, Pál; Donal, Erwan; Maurer, Gerald & Popescu, Bogdan Alexandru (2018). The year 2017 in the European Heart Journal-Cardiovascular Imaging: Part II. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  19(11), s 1222- 1229 . doi: 10.1093/ehjci/jey110 Fulltekst i vitenarkiv.
• Fumagalli, Stefano; Pieragnoli, Paolo; Haugaa, Kristina; Potpara, Tatjana S.; Rasero, Laura; Ramacciati, Nicola; Ricciardi, Giuseppe; Solimene, Francesco; Mascia, Giuseppe; Mascioli, Giosuè; Zuo, Giulia; Roberts, Anna T.; Marchionni, Niccolò; Lenarczyk, Radoslaw; Boveda, Serge & Dagres, Nikolaos (2018). The influence of age on the psychological profile of patients with cardiac implantable electronic devices: results from the Italian population in a multicenter study conducted by the European Heart Rhythm Association. Aging Clinical and Experimental Research.  ISSN 1594-0667.  s 1- 8 . doi: 10.1007/s40520-018-1088-5
• Gibbs, Charlotte Christine; Thalamus, Jacob; Tveten, Kristian; Busk, Øyvind; Hysing, Jan; Haugaa, Kristina & Holla, Øystein Lunde (2018). Genetic and phenotypic characterization of community hospital patients with QT prolongation. Journal of the American Heart Association (JAHA).  ISSN 2047-9980.  7(16), s 1- 11 . doi: 10.1161/JAHA.118.009706 Fulltekst i vitenarkiv.
• Gilljam, Thomas; Haugaa, Kristina; Jensen, Henrik K; Svensson, Anneli; Bundgaard, Henning; Hansen, Jim; Dellgren, Göran; Gustafsson, Finn; Eiskjær, Hans; Andreassen, Arne K.; Sjögren, Johan; Edvardsen, Thor; Holst, Anders G.; Svendsen, Jesper Hastrup & Platonov, Pyotr G. (2018). Heart transplantation in arrhythmogenic right ventricular cardiomyopathy ? Experience from the Nordic ARVC Registry. International Journal of Cardiology.  ISSN 0167-5273.  250, s 201- 206 . doi: 10.1016/j.ijcard.2017.10.076 Fulltekst i vitenarkiv.
• Gonzalez Figuera, Alba Marina; Aurlien, Dag; Haugaa, Kristina & Taubøll, Erik (2018). Epilepsy in patients with long QT syndrome type 1: A Norwegian family. Epilepsy and Behavior Case Reports (EBCR).  ISSN 2213-3232.  10, s 118- 121 . doi: 10.1016/j.ebcr.2018.09.006 Fulltekst i vitenarkiv. Vis sammendrag

  The congenital long QT syndrome (cLQTS) is an inherited cardiac disorder and is associated with sudden cardiac death. We describe a Norwegian family with mutations within the KCNQ1 gene causing cLQTS type 1 (LQT1) and epilepsy. The index patient had Jervell and Lange-Nielsen-syndrome (JLNS) with deafness and recurrent episodes of cardiac arrhythmia. The mother and the brother have Romano-Ward syndrome (RWS) with recurrent arrhythmias. Whereas the father has focal epilepsy and genetically verified LQT1, the sister has both focal epilepsy and RWS. Our findings are consistent with the notion that mutations in the KCNQ1 gene can cause epilepsy.

• Gonzalez Figuera, Alba Marina; Aurlien, Dag; Larsson, Pål Gunnar; Olsen, Ketil Berg; Dahl, Iselin Teresa; Edvardsen, Thor; Haugaa, Kristina & Taubøll, Erik (2018). Seizure-like episodes and EEG abnormalities in patients with long QT syndrome. Seizure.  ISSN 1059-1311.  61, s 214- 220 . doi: 10.1016/j.seizure.2018.08.020
• Hasselberg, Nina Eide; Berge, Knut Erik; Rasmussen, Magnhild; Fruh, Andreas; Ørstavik, Kristin & Haugaa, Kristina (2018). Kardiomyopati ved arvelig skjelettmuskeldystrofi. Tidsskrift for Den norske legeforening.  ISSN 0029-2001.  138(1) . doi: 10.4045/tidsskr.16.0683 Vis sammendrag

  En rekke genetiske skjelettmuskeldystrofier er assosiert med kardiomyopati med hjertesviktutvikling og risiko for plutselig død. Grad av kardial affeksjon er ikke nødvendigvis relatert til grad av skjelettmuskelaffeksjon, og plutselig hjertedød kan være første tegn på kardiomyopati. For å iverksette behandling og forebyggende tiltak mot livstruende kardiale hendelser er det nødvendig med økt oppmerksomhet blant allmennleger og spesialister.

• Hasselberg, Nina Eide; Håland, Trine Synnøve Fink; Saberniak, Jørg; Brekke, Pål Haugar; Berge, Knut Erik; Leren, Trond Paul; Edvardsen, Thor & Haugaa, Kristina (2018). Lamin A/C cardiomyopathy: Young onset, high penetrance, and frequent need for heart transplantation. European Heart Journal.  ISSN 0195-668X.  39(10), s 853- 860 . doi: 10.1093/eurheartj/ehx596 Fulltekst i vitenarkiv.
• Haugaa, Kristina; Dan, Gheorghe-Andrei; Iliodromitis, Konstantinos; Lenarczyk, Radosław; Marinskis, Germanas; Osca, Joaquin; Scherr, Daniel & Dagres, Nikolaos (2018). Management of patients with ventricular arrhythmias and prevention of sudden cardiac death-translating guidelines into practice: results of the European Heart Rhythm Association survey. Europace.  ISSN 1099-5129.  20(2), s f249- f253 . doi: 10.1093/europace/euy112
• Haugaa, Kristina; Potpara, Tatjana S.; Boveda, Serge; Deharo, Jean-Claude; Chen, Jian; Dobreanu, Dan; Fumagalli, Stefano; Lenarczyk, Radoslaw; Hernandez Madrid, Antonio; Larsen, Torben Bjerregaard; Sciarrafia, Elena; Taborsky, Milos; Tilz, Roland Richard; Pieragnoli, Paolo; Przybylski, Andrzej & Dagres, Nikolaos (2018). Patients' knowledge and attitudes regarding living with implantable electronic devices: Results of a multicentre, multinational patient survey conducted by the European Heart Rhythm Association. Europace.  ISSN 1099-5129.  20(2), s 386- 391 . doi: 10.1093/europace/eux365 Fulltekst i vitenarkiv.
• Lenarczyk, Radoslaw; Boveda, Serge; Haugaa, Kristina; Potpara, Tatjana S.; Syska, Pawel; Jędrzejczyk-Patej, Ewa; Chauvin, Michel; Sadoul, Nicolas & Dagres, Nikolaos (2018). Peri-procedural routines, implantation techniques, and procedure-related complications in patients undergoing implantation of subcutaneous or transvenous automatic cardioverter-defibrillators: Results of the European Snapshot Survey on S-ICD Implantation (ESSS-SICDI). Europace.  ISSN 1099-5129.  20(7), s 1218- 1224 . doi: 10.1093/europace/euy092
• Lie, Øyvind Haugen; Dejgaard, Lars; Saberniak, Jørg; Rootwelt, Christine; Stokke, Mathis Korseberg; Edvardsen, Thor & Haugaa, Kristina (2018). Harmful effects of exercise intensity and exercise duration in patients with arrhythmogenic cardiomyopathy. JACC: Clinical Electrophysiology.  ISSN 2405-500X.  4(6), s 744- 753 . doi: 10.1016/j.jacep.2018.01.010 Fulltekst i vitenarkiv.
• Lie, Øyvind Haugen; Rootwelt, Christine; Dejgaard, Lars; Leren, Ida Skrinde; Stokke, Mathis Korseberg; Edvardsen, Thor & Haugaa, Kristina (2018). Prediction of Life-Threatening Ventricular Arrhythmia in Patients With Arrhythmogenic Cardiomyopathy: A Primary Prevention Cohort Study. JACC Cardiovascular Imaging.  ISSN 1936-878X.  11(10), s 1377- 1386 . doi: 10.1016/j.jcmg.2018.05.017 Fulltekst i vitenarkiv.
• Linde, Cecilia; Bongiorni, Maria Grazia; Birgersdotter-Green, Ulrika; Curtis, Anne B.; Deisenhofer, Isabel; Furokawa, Tetsushi; Gillis, Anne M.; Haugaa, Kristina; Lip, Gregory Y.H.; van Gelder, Isabelle; Malik, Marek; Poole, Jeannie; Potpara, Tatjana; Savelieva, Irina & Sarkozy, Andrea (2018). Sex differences in cardiac arrhythmia: a consensus document of the European Heart Rhythm Association, endorsed by the Heart Rhythm Society and Asia Pacific Heart Rhythm Society. Europace.  ISSN 1099-5129.  20:1565(10), s 1565a- 1565o . doi: 10.1093/europace/euy067
• Popescu, Bogdan A.; Petersen, Steffen E.; Maurovich-Horvat, Pál; Haugaa, Kristina; Donal, Erwan; Maurer, Gerald & Edvardsen, Thor (2018). The year 2017 in the European Heart Journal - Cardiovascular Imaging: Part i. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  19(10), s 1099- 1106 . doi: 10.1093/ehjci/jey109
• Tilz, Roland Richard; Lenarczyk, Radosław; Scherr, Daniel; Haugaa, Kristina; Iliodromitis, Konstantinos; Purerfellner, Helmut; Kiliszek, Marek & Dagres, Nikolaos (2018). Management of ventricular tachycardia in the ablation era: Results of the European Heart Rhythm Association Survey. Europace.  ISSN 1099-5129.  20(1), s 209- 213 . doi: 10.1093/europace/eux332
• Broch, Kaspar; Leren, Ida Skrinde; Saberniak, Jørg; Ueland, Thor; Edvardsen, Thor; Gullestad, Lars & Haugaa, Kristina (2017). Soluble ST2 is associated with disease severity in arrhythmogenic right ventricular cardiomyopathy. Biomarkers.  ISSN 1354-750X.  22(3-4), s 367- 371 . doi: 10.1080/1354750X.2016.1278266
• Dejgaard, Lars; Håland, Trine Synnøve Fink; Lie, Øyvind Haugen; Ribe, Margareth; Bjune, Thea; Leren, Ida Skrinde; Berge, Knut Erik; Edvardsen, Thor & Haugaa, Kristina (2017). Data on exercise and cardiac imaging in a patient cohort with hypertrophic cardiomyopathy. Data in Brief.  ISSN 2352-3409.  15, s 30- 39 . doi: 10.1016/j.dib.2017.08.018
• Fumagalli, Stefano; Potpara, Tatjana S; Bjerregaard Larsen, Torben; Haugaa, Kristina; Dobreanu, Dan; Proclemer, Alessandro & Dagres, Nicolaus (2017). Frailty syndrome: An emerging clinical problem in the everyday management of clinical arrhythmias. the results of the European Heart Rhythm Association survey. Europace.  ISSN 1099-5129.  19(11), s 1896- 1902 . doi: 10.1093/europace/eux288
• Gibbs, Charlotte; Thalamus, Jacob; Heldal, Kristian; Holla, Øystein Lunde; Haugaa, Kristina & Hysing, Jan (2017). Predictors of mortality in high-risk patients with QT prolongation in a community hospital. Europace.  ISSN 1099-5129.  20(1), s f99- f107 . doi: 10.1093/europace/eux286
• Haugaa, Kristina; Basso, Cristina; Badano, Luigi P; Bucciarelli-Ducci, Chiara; Cardim, Nuno; Gaemperli, Oliver; Galderisi, Maurizio; Habib, Gilbert; Knuuti, Juhani; Lancellotti, Patrizio; Mckenna, William; Neglia, Danilo; Popescu, Bogdan A. & Edvardsen, Thor (2017). Comprehensive multi-modality imaging approach in arrhythmogenic cardiomyopathy - an expert consensus document of the European Association of Cardiovascular Imaging. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  18(3), s 237- 253 . doi: 10.1093/ehjci/jew229
• Haugaa, Kristina; Tilz, Roland Richard; Boveda, Serge; Dobreanu, Dan; Sciaraffia, Elena; Mansourati, Jacques; Papiashvili, Giorgi & Dagres, Nikolaos (2017). Implantable cardioverter defibrillator use for primary prevention in ischaemic and non-ischaemic heart disease - Indications in the post-DANISH trial era: Results of the European Heart Rhythm Association survey. Europace.  ISSN 1099-5129.  19(4), s 660- 664 . doi: 10.1093/europace/eux089
• Hetland, Sveinung Arild; Haugaa, Kristina; Vistnes, Maria; Liland, Kristian Hovde; Olseng, Margareth; Jacobsen, Morten & Edvardsen, Thor (2017). A retrospective analysis of cardiovascular outcomes in patients treated with ASV. Scandinavian Cardiovascular Journal.  ISSN 1401-7431.  51(2), s 106- 113 . doi: 10.1080/14017431.2016.1262546
• Hetland, Sveinung Arild; Lerum, Tøri Vigeland; Haugaa, Kristina & Edvardsen, Thor (2017). Patients with Cheyne-Stokes respiration and heart failure: patient tolerance after three-month discontinuation of treatment with adaptive servo-ventilation. Heart and Vessels.  ISSN 0910-8327.  Published ahead of print, s 1- 7 . doi: 10.1007/s00380-017-0951-1
• Håland, Trine Synnøve Fink; Hasselberg, Nina Eide; Almaas, Vibeke Marie; Dejgaard, Lars; Saberniak, Jørg; Leren, Ida Skrinde; Berge, Knut Erik; Haugaa, Kristina & Edvardsen, Thor (2017). The systolic paradox in hypertrophic cardiomyopathy. Open heart.  ISSN 2053-3624.  4(1) . doi: 10.1136/openhrt-2016-000571
• Håland, Trine Synnøve Fink; Saberniak, Jørg; Leren, Ida Skrinde; Edvardsen, Thor & Haugaa, Kristina (2017). Echocardiographic comparison between left ventricular non-compaction and hypertrophic cardiomyopathy. International Journal of Cardiology.  ISSN 0167-5273.  228, s 900- 905 . doi: 10.1016/j.ijcard.2016.11.162 Fulltekst i vitenarkiv.
• Klæboe, Lars Gunnar; Håland, Trine Synnøve Fink; Leren, Ida Skrinde; ter Bekke, Rachel M. A.; Brekke, Pål Haugar; Røsjø, Helge; Omland, Torbjørn; Gullestad, Lars; Aakhus, Svend; Haugaa, Kristina & Edvardsen, Thor (2017). Prognostic Value of Left Ventricular Deformation Parameters in Patients with Severe Aortic Stenosis: A Pilot Study of the Usefulness of Strain Echocardiography. Journal of the American Society of Echocardiography.  ISSN 0894-7317.  30(8), s 727- 735.e1 . doi: 10.1016/j.echo.2017.04.009 Fulltekst i vitenarkiv.
• Lenarczyk, Radosław; Potpara, Tatjana S.; Haugaa, Kristina; Deharo, Jean-Claude; Hernández-Madrid, Antonio; Del Carmen Exposito Pineda, Maria; Kiliszek, Marek & Dagres, Nikolaos (2017). Approach to cardio-oncologic patients with special focus on patients with cardiac implantable electronic devices planned for radiotherapy: Results of the European Heart Rhythm Association survey. Europace.  ISSN 1099-5129.  19(9), s 1579- 1584 . doi: 10.1093/europace/eux195
• Leren, Ida Skrinde; Saberniak, Jørg; Håland, Trine Synnøve Fink; Edvardsen, Thor & Haugaa, Kristina (2017). Combination of ECG and Echocardiography for Identification of Arrhythmic Events in Early ARVC. JACC Cardiovascular Imaging.  ISSN 1936-878X.  10(5), s 503- 513 . doi: 10.1016/j.jcmg.2016.06.011 Fulltekst i vitenarkiv. Vis sammendrag

  OBJECTIVES: The aim of this study was to investigate early markers of arrhythmic events (AEs) and improve risk stratification in early arrhythmogenic right ventricular cardiomyopathy (ARVC). BACKGROUND: AEs are frequent in patients with ARVC, but risk stratification in subjects with early ARVC is challenging. METHODS: Early ARVC disease was defined as possible or borderline ARVC diagnosis according to the ARVC Task Force Criteria 2010. We performed resting and signal averaged electrocardiogram (ECG). Using echocardiography, we assessed right ventricular (RV) outflow tract diameter and right ventricular basal diameter (RV diameter). Global longitudinal strain and mechanical dispersion (MD) from strain echocardiography were assessed in both the right and left ventricle. AEs were defined as documented ventricular tachycardia, cardiac syncope, or aborted cardiac arrest. RESULTS: Of 162 included subjects with ARVC (41 ± 16 years of age, 47% female), 73 had early ARVC, including mutation positive family members not fulfilling definite ARVC diagnosis. AEs occurred in 15 (21%) subjects with early ARVC. Those with AEs in early disease had larger RV diameter (40 ± 4 mm vs. 37 ± 5 mm), more pronounced RVMD (39 ± 15 ms vs. 26 ± 11 ms), and more pathological signal averaged ECGs compared with those without AEs (all p ≤ 0.05). Adding measurements of RV diameter and RVMD to electrical parameters improved identification of subjects with AEs compared with electrical parameters alone (p = 0.05). CONCLUSIONS: ECG parameters, RV diameter, and RVMD were markers of previous arrhythmic events in patients with early ARVC. A combination of electrical and echocardiographic parameters improved identification of subjects with AEs in early ARVC disease. Copyright © 2017 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. KEYWORDS: arrhythmic risk; arrhythmogenic right ventricular cardiomyopathy; echocardiography; signal averaged ECG; ventricular arrhythmias

• Nestaas, Eirik; Shih, Jhih-Yuan; Smedsrud, Marit Kristine; Gjesdal, Ola; Hopp, Einar; Haugaa, Kristina & Edvardsen, Thor (2017). Comparison of Electrocardiography Markers and Speckle Tracking Echocardiography for Assessment of Left Ventricular Myocardial Scar Burden in Patients With Previous Myocardial Infarction. American Journal of Cardiology.  ISSN 0002-9149.  119(9), s 1307- 1312 . doi: 10.1016/j.amjcard.2017.01.020 Fulltekst i vitenarkiv.
• Stokke, Thomas Muri; Hasselberg, Nina Eide; Smedsrud, Marit Kristine; Sarvari, Sebastian Imre; Haugaa, Kristina; Smiseth, Otto A.; Edvardsen, Thor & Remme, Espen W. (2017). Geometry as a Confounder When Assessing Ventricular Systolic Function: Comparison Between Ejection Fraction and Strain. Journal of the American College of Cardiology.  ISSN 0735-1097.  70(8), s 942- 954 . doi: 10.1016/j.jacc.2017.06.046
• Tilz, Roland Richard; Potpara, Tatjana; Chen, Jian; Dobreanu, Dan; Larsen, Torben Bjerregaard; Haugaa, Kristina & Dagres, Nikolaos (2017). Left atrial appendage occluder implantation in Europe: Indications and anticoagulation post-implantation. Results of the European Heart Rhythm Association Survey. Europace.  ISSN 1099-5129.  19(10), s 1737- 1742 . doi: 10.1093/europace/eux254
• Timmermann, Viviane; Dejgaard, Lars; Haugaa, Kristina; Edwards, Andrew; Sundnes, Joakim; McCulloch, Andrew D. & Wall, Samuel Thomas (2017). An integrative appraisal of mechano-electric feedback mechanisms in the heart. Progress in Biophysics and Molecular Biology.  ISSN 0079-6107.  130, s 404- 417 . doi: 10.1016/j.pbiomolbio.2017.08.008
• Turkowski, Kari L.; Tester, David J.; Bos, J. Martijn; Haugaa, Kristina & Ackerman, Michael J. (2017). Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy. Congenital Heart Disease.  ISSN 1747-079X.  12(2), s 226- 235 . doi: 10.1111/chd.12462

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• Dalen, Håvard; Forfang, Kolbjørn; Haugaa, Kristina; Istad, Helge & Wiseth, Rune (red.) (2019). Kardiologi - Klinisk veileder, 3.utgave. Gyldendal Akademisk.  ISBN 9788205523951.  454 s.

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• Donal, Erwan; Delgado, Victoria; Bucciarelli-Ducci, Chiara; Galli, Elena; Haugaa, Kristina; Charron, Philippe; Voigt, Jens-Uwe; Cardim, Nuno; Masci, Pier Giorgio; Galderisi, Maurizio; Gaemperli, Oliver; Gimelli, Alessia; Pinto, Yigal M.; Lancellotti, Patrizio; Habib, Gilbert; Elliott, Perry; Edvardsen, Thor; Cosyns, Bernard & Popescu, Bogdan A. (2019). Multimodality imaging in the diagnosis, risk stratification, and management of patients with dilated cardiomyopathies: An expert consensus document from the European Association of Cardiovascular Imaging. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  20(10), s 1075- 1093 . doi: 10.1093/ehjci/jez178
• Edvardsen, Thor & Haugaa, Kristina (2019). Stretch and Rebound in the Search for Cardiac Resynchronization Therapy Candidates. JACC Cardiovascular Imaging.  ISSN 1936-878X.  12(9), s 1753- 1754 . doi: 10.1016/j.jcmg.2018.08.008
• Haugaa, Kristina & Stokke, Mathis Korseberg (2019). Cardiac electrical and mechanical alterations - united in the long QT syndrome. International Journal of Cardiology.  ISSN 0167-5273.  274, s 190- 191 . doi: 10.1016/j.ijcard.2018.09.048 Fulltekst i vitenarkiv.
• Werf, Christian van der; Lieve, Krystien V; Bos, J. Martijn; Lan, Conor M; Denjoy, Isabelle; Roses-Noguer, Ferran; Aiba, Takeshi; Wada, Yuko; Ingles, Jodie; Leren, Ida Skrinde; Rudic, Boris; Schwartz, Peter J.; Maltret, Alice; Sacher, Frederic; Skinner, Jonathan R.; Krahn, Andrew D.; Roston, Thomas M; Tfelt-Hansen, Jacob; Swan, Heikki; Robyns, Tomas; Ohno, Seiko; Roberts, Jason D; Berg, Maarten P van der; Kammeraad, Janneke A; Probst, Vincent; Kannankeril, Prince J; Blom, Nico A; Behr, Elijah R; Borggrefe, Martin; Haugaa, Kristina; Semsarian, Christopher; Horie, Minoru; Shimizu, Wataru; Till, Janice A.; Leenhardt, Antonie; Ackerman, Michael J. & Wilde, Arthur A.M. (2019). Implantable cardioverter-defibrillators inpreviously undiagnosed patients withcatecholaminergic polymorphicventricular tachycardia resuscitatedfrom sudden cardiac arrest. European Heart Journal.  ISSN 0195-668X.  40, s 2953- 2961 . doi: 10.1093/eurheartj/ehz309
• Haugaa, Kristina & Dejgaard, Lars (2018). Global longitudinal strain: Ready for clinical use and guideline implementation. Journal of the American College of Cardiology.  ISSN 0735-1097.  71(18), s 1958- 1959 . doi: 10.1016/j.jacc.2018.03.015
• Haugaa, Kristina & Lie, Øyvind Haugen (2018). Reveal the concealed. The quest for early disease detection in family members at risk of developing arrhythmogenic cardiomyopathy. JACC Cardiovascular Imaging.  ISSN 1936-878X.  s 1- 2 . doi: 10.1016/j.jcmg.2018.02.007
• Jurcut, Ruxandra; Haugaa, Kristina & La Gerche, Andre (2018). The right ventricle: From bench to bedside. BioMed Research International.  ISSN 2314-6133.  2018:2868437, s 1- 3 . doi: 10.1155/2018/2868437
• Magne, Julien; Bucciarelli-Ducci, Chiara; Dahl, Jordi S.; Gimelli, Alessia; Haugaa, Kristina; Miller, Owen; Muraru, Denisa; Donal, Erwan; Edvardsen, Thor & Popescu, Bogdan A. (2018). EuroEcho-imaging 2017: Highlights. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  19(5), s 482- 489 . doi: 10.1093/ehjci/jey037
• Gorcsan, John & Haugaa, Kristina (2017). Ventricular arrhythmias and reduced echocardiographic inferior wall strain: is regional function an important risk marker?. Circulation Cardiovascular Imaging.  ISSN 1941-9651.  10:e005900(1) . doi: 10.1161/CIRCIMAGING.116.005900
• Haugaa, Kristina; Edvardsen, Thor & Smiseth, Otto A. (2017). Mechanical dyssynchrony - Resurrected as a flashing and rocking parameter to predict prognosis after cardiac resynchronization therapy. European Heart Journal-Cardiovascular Imaging.  ISSN 2047-2404.  18(10), s 1118- 1119 . doi: 10.1093/ehjci/jex198

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