Siste publikasjoner

• Lemma, Roza Berhanu; Ledsaak, Marit; Fuglerud, Bettina Maria; Sandve, Geir Kjetil; Eskeland, Ragnhild & Gabrielsen, Odd Stokke (2021). Chromatin occupancy and target genes of the haematopoietic master transcription factor MYB. Scientific Reports. ISSN 2045-2322. 11(9008). doi: 10.1038/s41598-021-88516-w. Vis sammendrag

  The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB levels. Despite much accumulated molecular knowledge of MYB, we still lack a comprehensive understanding of its target genes and its chromatin action. In the present work, we performed a ChIP-seq analysis of MYB in K562 cells accompanied by detailed bioinformatics analyses. We found that MYB occupies both promoters and enhancers. Five clusters (C1–C5) were found when we classified MYB peaks according to epigenetic profiles. C1 was enriched for promoters and C2 dominated by enhancers. C2-linked genes were connected to hematopoietic specific functions and had GATA factor motifs as second in frequency. C1 had in addition to MYB-motifs a significant frequency of ETS-related motifs. Combining ChIP-seq data with RNA-seq data allowed us to identify direct MYB target genes. We also compared ChIP-seq data with digital genomic footprinting. MYB is occupying nearly a third of the super-enhancers in K562. Finally, we concluded that MYB cooperates with a subset of the other highly expressed TFs in this cell line, as expected for a master regulator

• Lopes-Ramos, Camila; Belova, Tatiana; Brunner, Tess; Ben Guebila, Marouen; Osorio, Daniel & Quackenbush, John [Vis alle 7 forfattere av denne artikkelen] (2021). Regulatory network of PD1 signaling is associated with prognosis in glioblastoma multiforme. Cancer Research. ISSN 0008-5472. 81(21), s. 5401–5412. doi: 10.1158/0008-5472.CAN-21-0730.
• Leipart, Vilde; Montserrat-Canals, Mateu; Cunha, Eva S.; Luecke, Hartmut; Herrero-Galán, Elías & Halskau, Øyvind [Vis alle 7 forfattere av denne artikkelen] (2021). Structure prediction of honey bee vitellogenin: a multi-domain protein important for insect immunity. FEBS Open Bio. ISSN 2211-5463. doi: 10.1002/2211-5463.13316.
• Chu, Dinh Toi; Phuong, Thuy Nguyen Thi; Tien, Nguyen Le Bao; Tran, Dang Khoa; Thanh, Vo Van & Quang, Thuy Luu [Vis alle 11 forfattere av denne artikkelen] (2020). An update on the progress of isolation, culture, storage, and clinical application of human bone marrow mesenchymal stem/stromal cells. International Journal of Molecular Sciences. ISSN 1422-0067. 21:708(3), s. 1–27. doi: 10.3390/ijms21030708. Fulltekst i vitenarkiv
• Gawel, Kinga Aurelia; Kukula-Koch, Wirginia; Nieoczym, Dorota; Stępnik, Katarzyna; van der Ent, Wietske & Banono, Nancy Saana [Vis alle 9 forfattere av denne artikkelen] (2020). The Influence of Palmatine Isolated from Berberis sibirica Radix on Pentylenetetrazole-Induced Seizures in Zebrafish. Cells. ISSN 2073-4409. 9(5). doi: 10.3390/cells9051233. Fulltekst i vitenarkiv
• Weikum, Julia; Kulakova, Alina; Tesei, Giulio; Yoshimoto, Shogo; Vejby Jægerum, Line & Schütz, Monika [Vis alle 11 forfattere av denne artikkelen] (2020). The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action. Scientific Reports. ISSN 2045-2322. 10(1). doi: 10.1038/s41598-020-77706-7. Fulltekst i vitenarkiv
• Guldvik, Ingrid Jenny; Zuber, Verena; Braadland, Peder Rustøen; Grytli, Helene Hartvedt; Ramberg, Håkon Andre & Lilleby, Wolfgang [Vis alle 18 forfattere av denne artikkelen] (2020). Identification and Validation of Leucine-rich alpha-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. European Urology Open Science. ISSN 2666-1691. 21, s. 51–61. doi: 10.1016/j.euros.2020.08.007. Fulltekst i vitenarkiv
• Wang, Shixiong; Somisetty, Venkata Satheesh; Bai, Baoyan; Chernukhin, Igor; Niskanen, Henri & Kaikkonen, Minna [Vis alle 9 forfattere av denne artikkelen] (2020). The proapoptotic gene interferon regulatory factor-1 mediates the antiproliferative outcome of paired box 2 gene and tamoxifen. Oncogene. ISSN 0950-9232. 39, s. 6300–6312. doi: 10.1038/s41388-020-01435-4. Fulltekst i vitenarkiv
• Pladsen, Arne Valebjørg; Nilsen, Gro; Rueda, Oscar M.; Aure, Miriam Ragle; Borgan, Ørnulf & Liestøl, Knut [Vis alle 18 forfattere av denne artikkelen] (2020). DNA copy number motifs are strong and independent predictors of survival in breast cancer. Communications Biology. ISSN 2399-3642. 3. doi: 10.1038/s42003-020-0884-6. Fulltekst i vitenarkiv
• Mohammadzadeh, Naiyereh; Melleby, Arne Olav; Palmero, Sheryl; Sjaastad, Ivar; Chakravarti, Shukti & Engebretsen, Kristin V Thunheim [Vis alle 9 forfattere av denne artikkelen] (2020). Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload. Cardiology. ISSN 0008-6312. 145(3), s. 187–198. doi: 10.1159/000505318.
• Tuovinen, Elina A.; Grönholm, Juha; Ohman, Tiina; Pöysti, Sakari; Toivonen, Raine & Kreutzman, Anna [Vis alle 17 forfattere av denne artikkelen] (2020). Novel Hemizygous IL2RG p.(Pro58Ser) Mutation Impairs IL-2 Receptor Complex Expression on Lymphocytes Causing X-Linked Combined Immunodeficiency. Journal of Clinical Immunology. ISSN 0271-9142. 40(3), s. 503–514. doi: 10.1007/s10875-020-00745-2. Fulltekst i vitenarkiv
• Lindner, Paula Maria; Christensen, Søren Brøgger; Nissen, Poul; Møller, Jesper Vuust & Engedal, Nikolai (2020). Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components. Cell Communication and Signaling. ISSN 1478-811X. 18(1), s. 1–23. doi: 10.1186/s12964-019-0499-z. Fulltekst i vitenarkiv
• Gözen, Irep & Dommersnes, Paul Gunnar (2020). Biological lipid nanotubes and their potential role in evolution. The European Physical Journal Special Topics. ISSN 1951-6355. 229(17-18), s. 2843–2862. doi: 10.1140/epjst/e2020-000130-7. Fulltekst i vitenarkiv
• Spustová, Karolina; Köksal, Elif; Ainla, Alar & Gözen, Irep (2020). Subcompartmentalization and Pseudo‐Division of Model Protocells. Small. ISSN 1613-6810. 17(2). doi: 10.1002/smll.202005320.
• Cieslar-Pobuda, Artur; Ahrens, Theresa Dorothee; Caglayan, Safak; Behringer, Sidney; Hannibal, Luciana & Staerk, Judith (2020). DNMT3B deficiency alters mitochondrial biogenesis and α‐ketoglutarate levels in human embryonic stem cells. Stem Cells. ISSN 1066-5099. 38(11), s. 1409–1422. doi: 10.1002/stem.3256. Fulltekst i vitenarkiv Vis sammendrag

  Embryonic stem cell renewal and differentiation is regulated by metabolites that serve as cofactors for epigenetic enzymes. An increase of α‐ketoglutarate (α‐KG), a cofactor for histone and DNA demethylases, triggers multilineage differentiation in human embryonic stem cells (hESCs). To gain further insight into how the metabolic fluxes in pluripotent stem cells can be influenced by inactivating mutations in epigenetic enzymes, we generated hESCs deficient for de novo DNA methyltransferases (DNMTs) 3A and 3B. Our data reveal a bidirectional dependence between DNMT3B and α‐KG levels: a‐KG is significantly upregulated in cells deficient for DNMT3B, while DNMT3B expression is downregulated in hESCs treated with α‐KG. In addition, DNMT3B null hESCs exhibit a disturbed mitochondrial fission and fusion balance and a switch from glycolysis to oxidative phosphorylation. Taken together, our data reveal a novel link between DNMT3B and the metabolic flux of hESCs.

• Caglayan, Safak; Hashim, Adnan; Cieslar-Pobuda, Artur; Jensen, Vidar; Behringer, Sidney & Talug, Burcu [Vis alle 16 forfattere av denne artikkelen] (2020). Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation. iScience. ISSN 2589-0042. 23(6). doi: 10.1016/j.isci.2020.101154. Fulltekst i vitenarkiv Vis sammendrag

  Optic atrophy 1 (OPA1), a GTPase at the inner mitochondrial membrane involved in regulating mitochondrial fusion, stability, and energy output, is known to be crucial for neural development: Opa1 heterozygous mice show abnormal brain development, and inactivating mutations in OPA1 are linked to human neurological disorders. Here, we used genetically modified human embryonic and patient-derived induced pluripotent stem cells and reveal that OPA1 haploinsufficiency leads to aberrant nuclear DNA methylation and significantly alters the transcriptional circuitry in neural progenitor cells (NPCs). For instance, expression of the forkhead box G1 transcription factor, which is needed for GABAergic neuronal development, is repressed in OPA1+/− NPCs. Supporting this finding, OPA1+/− NPCs cannot give rise to GABAergic interneurons, whereas formation of glutamatergic neurons is not affected. Taken together, our data reveal that OPA1 controls nuclear DNA methylation and expression of key transcription factors needed for proper neural cell specification.

• Arain, Fizza Kanwal; Abraityte, Judita Aurelija; Bogdanova, Mariia; Solberg, Ole Geir; Michelsen, Annika & Lekva, Tove [Vis alle 19 forfattere av denne artikkelen] (2020). YKL-40 (Chitinase-3-Like Protein 1) Serum Levels in Aortic Stenosis. Circulation: Heart Failure. ISSN 1941-3289. 13(10). doi: 10.1161/CIRCHEARTFAILURE.119.006643. Fulltekst i vitenarkiv
• Perdreau-Dahl, Harmonie; Progida, Cinzia; Barfeld, Stefan Jörg; Guldsten, Hanne; Thiede, Bernd & Arntzen, Magnus Øverlie [Vis alle 10 forfattere av denne artikkelen] (2020). Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells. Communications Biology. ISSN 2399-3642. 3(1). doi: 10.1038/s42003-020-0851-2.
• Khalid, Khalisanni; Tan, Xuefei; Mohd Zaid, Hayyiratul Fatimah; Tao, Yang; Lye Chew, Chien & Chu, Dinh Toi [Vis alle 10 forfattere av denne artikkelen] (2020). Advanced in developmental organic and inorganic nanomaterial: a review. Bioengineered. ISSN 2165-5979. 11(1), s. 328–355. doi: 10.1080/21655979.2020.1736240. Fulltekst i vitenarkiv
• Villatoro, Alicia; Konieczny, Joanna; Cuminetti, Vincent & Arranz, Lorena (2020). Leukemia Stem Cell Release From the Stem Cell Niche to Treat Acute Myeloid Leukemia. Frontiers in Cell and Developmental Biology. ISSN 2296-634X. 8. doi: 10.3389/fcell.2020.00607. Fulltekst i vitenarkiv
• Mahmutovic, Anel; Abel zur Wiesch, Pia & Abel, Sören (2020). Selection or drift: the population biology underlying transposon insertion sequencing experiments. Computational and Structural Biotechnology Journal. ISSN 2001-0370. 18, s. 791–804. doi: 10.1016/j.csbj.2020.03.021. Fulltekst i vitenarkiv
• Clarelli, Fabrizio; Palmer, Adam; Singh, Bhupender; Storflor, Merete; Lauksund, Silje & Cohen, Ted [Vis alle 8 forfattere av denne artikkelen] (2020). Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones. PLoS Computational Biology. ISSN 1553-734X. doi: 10.1371/journal.pcbi.1008106. Fulltekst i vitenarkiv
• Köksal, Elif; Liese, Susanne; Xue, Lin; Ryskulov, Ruslan; Viitala, Lauri & Carlson, Andreas [Vis alle 7 forfattere av denne artikkelen] (2020). Rapid Growth and Fusion of Protocells in Surface‐Adhered Membrane Networks. Small. ISSN 1613-6810. 16(38). doi: 10.1002/smll.202002529.
• Taboada-Castro, Hermenegildo; Castro Mondragón, Jaime Abraham; Aguilar-Vera, Alejandro; Hernández-Álvarez, Alfredo José; van Helden, Jacques & Encarnación-Guevara, Sergio (2020). RhizoBindingSites, a Database of DNA-Binding Motifs in Nitrogen-Fixing Bacteria Inferred Using a Footprint Discovery Approach. Frontiers in Microbiology. ISSN 1664-302X. 11, s. 1–11. doi: 10.3389/fmicb.2020.567471. Fulltekst i vitenarkiv
• Harjama, Liisa; Kettunen, Kaisa; Elomaa, Outi; Einarsdottir, Elisabet; Heikkilä, Hannele & Kivirikko, Sirpa [Vis alle 13 forfattere av denne artikkelen] (2020). Phenotypic Variability with SLURP1 Mutations and Diffuse Palmoplantar Keratoderma. Acta Dermato-Venereologica. ISSN 0001-5555. 100(4). doi: 10.2340/00015555-3404. Fulltekst i vitenarkiv
• Hakonen, Anna H; Lehtonen, Johanna; Kivirikko, Sirpa; Keski‐Filppula, Riikka; Moilanen, Jukka & Kivisaari, Reetta [Vis alle 11 forfattere av denne artikkelen] (2020). Recessive MYH3 variants cause “Contractures, pterygia, and variable skeletal fusions syndrome 1B” mimicking Escobar variant multiple pterygium syndrome. American Journal of Medical Genetics. Part A. ISSN 1552-4825. 182(11), s. 2605–2610. doi: 10.1002/ajmg.a.61836.
• Hautala, Timo; Chen, Jie; Tervonen, Laura; Partanen, Terhi; Winqvist, Satu & Lehtonen, Johanna [Vis alle 17 forfattere av denne artikkelen] (2020). Herpes simplex virus 2 encephalitis in a patient heterozygous for a TLR3 mutation. Neurology: Genetics. ISSN 2376-7839. 6(6). doi: 10.1212/NXG.0000000000000532. Fulltekst i vitenarkiv
• Hannula-Jouppi, Katariina; Harjama, Liisa; Einarsdottir, Elisabet; Elomaa, Outi; Kettunen, Kaisa & Saarela, Janna [Vis alle 14 forfattere av denne artikkelen] (2020). Nagashima-type palmoplantar keratosis in Finland caused by a SERPINB7 founder mutation. Journal of American Academy of Dermatology. ISSN 0190-9622. 83(2), s. 643–645. doi: 10.1016/j.jaad.2019.11.004. Fulltekst i vitenarkiv
• Partanen, Terhi; Chen, Jie; Lehtonen, Johanna; Kuismin, Outi; Rusanen, Harri & Vapalahti, Olli [Vis alle 21 forfattere av denne artikkelen] (2020). Heterozygous TLR3 Mutation in Patients with Hantavirus Encephalitis. Journal of Clinical Immunology. ISSN 0271-9142. 40(8). doi: 10.1007/s10875-020-00834-2. Fulltekst i vitenarkiv
• Köksal, Elif; Liese, Susanne; Kantarci, Ilayda; Olsson, Ragni; Carlson, Andreas & Gözen, Irep (2019). Nanotube-Mediated Path to Protocell Formation. ACS Nano. ISSN 1936-0851. 13(6), s. 6867–6878. doi: 10.1021/acsnano.9b01646. Fulltekst i vitenarkiv
• Bösl, Korbinian; Ianevski, Aleksandr; Than, Thoa T.; Anderssen, Petter Inge; Kuivanen, Suvi & Teppor, Mona [Vis alle 25 forfattere av denne artikkelen] (2019). Common nodes of virus-host interaction revealed through an integrated network analysis. Frontiers in Immunology. ISSN 1664-3224. 10. doi: 10.3389/fimmu.2019.02186. Fulltekst i vitenarkiv
• Post, Joakim Iver; Leergaard, Trygve B.; Ratz, Veronika; Walaas, S. Ivar; von Hörsten, Stephan & Nissen-Meyer, Lise Sofie Haug (2019). Differential Levels and Phosphorylation of Type 1 Inositol 1,4,5-Trisphosphate Receptor in Four Different Murine Models of Huntington Disease . Journal of Huntington's Disease. ISSN 1879-6397. 8(3), s. 271–289. doi: 10.3233/JHD-180301.
• Gözen, Irep (2019). A Hypothesis for Protocell Division on the Early Earth. ACS Nano. ISSN 1936-0851. 13(10), s. 10869–10871. doi: 10.1021/acsnano.9b06584.
• Kamiński, Krzysztof; Socała, Katarzyna; Zagaja, Mirosław; Andres-Mach, Marta; Abram, Michał & Jakubiec, Marcin [Vis alle 17 forfattere av denne artikkelen] (2019). N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug. Neurotherapeutics. ISSN 1933-7213. doi: 10.1007/s13311-019-00773-w. Fulltekst i vitenarkiv
• Korecki, Andrea J; Hickmott, Jack W; Lam, Siu Ling; Dreolini, Lisa; Mathelier, Anthony & Baker, Oliver [Vis alle 17 forfattere av denne artikkelen] (2019). Twenty-seven tamoxifen-inducible icre-driver mouse strains for eye and brain, including seventeen carrying a new inducible-first constitutive-ready allele. Genetics. ISSN 0016-6731. 211(4), s. 1155–1177. doi: 10.1534/genetics.119.301984.
• Skånland, Sigrid Strand; Cremaschi, Andrea; Bendiksen, Henrik; Hermansen, Johanne Uthus; Thimiri Govinda Raj, Deepak Balaji & Munthe, Ludvig Andre [Vis alle 8 forfattere av denne artikkelen] (2019). An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL. Leukemia. ISSN 0887-6924. doi: 10.1038/s41375-019-0569-7.
• Mayer, Alexander E.; Löffler, Mona C; Valdés, Angel E Loza; Schmitz, Werner; El-Merahbi, Rabih & Viera, Jonathan Trujillo [Vis alle 13 forfattere av denne artikkelen] (2019). The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling. Science Signaling. ISSN 1945-0877. 12(593). doi: 10.1126/scisignal.aav9150.
• Ali Ahmad, Ahmad; Bilokapic, Silvija; Schafer, Ingmar B; Halic, Mario & Sekulic, Nikolina (2019). CENP‐C unwraps the human CENP‐A nucleosome through the H2A C‐terminal tail. EMBO Reports. ISSN 1469-221X. doi: 10.15252/embr.201948913. Fulltekst i vitenarkiv
• Copmans, Daniëlle; Kildgaard, Sara; Rasmussen, Silas A.; Ślęzak, Monika; Dirkx, Nina & Partoens, Michèle [Vis alle 10 forfattere av denne artikkelen] (2019). Zebrafish-based discovery of antiseizure compounds from the north sea: Isoquinoline alkaloids TMC-120A and TMC-120B. Marine Drugs. ISSN 1660-3397. 17:607(11), s. 1–20. doi: 10.3390/md17110607. Fulltekst i vitenarkiv
• Vu, Le Nguyen; Nghia, Nguyen Quang; Thanh, Do Truong; Giang, Tran Binh; Nga, Vu Thi & Bui, Le Minh [Vis alle 7 forfattere av denne artikkelen] (2019). Nefrectomía laparoscópica derecha de donante vivo: evaluación del resultado y asociación del IMC con la longitud de la vena renal derecha. Actas Urológicas Españolas. ISSN 0210-4806. 43(10), s. 536–542. doi: 10.1016/j.acuro.2019.05.005.
• Rydmark, Marcella Orwick; Christensen, Mikkel; Köksal, Elif; Kantarci, Ilayda; Kustanovich, Kiryl & Yantchev, Ventsislav [Vis alle 8 forfattere av denne artikkelen] (2019). Styrene maleic acid copolymer induces pores in biomembranes . Soft Matter. ISSN 1744-683X. 15(39), s. 7934–7944. doi: 10.1039/C9SM01407A. Fulltekst i vitenarkiv
• Salvatore, Stefania; Rand, Knut Dagestad; Grytten, Ivar; Ferkingstad, Egil; Domanska, Diana & Holden, Lars [Vis alle 10 forfattere av denne artikkelen] (2019). Beware the Jaccard: the choice of similarity measure is important and non-trivial in genomic colocalisation analysis. Briefings in Bioinformatics. ISSN 1467-5463. s. 1–8. doi: 10.1093/bib/bbz083.
• Connell, Shea P; Yazbek-Hanna, Marcelino; McCarthy, Frank; Hurst, Rachel; Webb, Martyn & Curley, Helen [Vis alle 24 forfattere av denne artikkelen] (2019). A four‐group urine risk classifier for predicting outcomes in patients with prostate cancer. BJU International. ISSN 1464-4096. 124(4), s. 609–620. doi: 10.1111/bju.14811. Fulltekst i vitenarkiv
• Nielsen, Nis Valentin; Roedel, Elfie; Manna, Dipankar; Etscheid, Michael; Morth, Jens Preben & Kanse, Sandip (2019). Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP). Scientific Reports. ISSN 2045-2322. 9(1). doi: 10.1038/s41598-019-55531-x. Fulltekst i vitenarkiv
• Cuminetti, Vincent & Arranz, Lorena (2019). Bone Marrow Adipocytes: The Enigmatic Components of the Hematopoietic Stem Cell Niche. Journal of Clinical Medicine. ISSN 2077-0383. 8(5). doi: 10.3390/jcm8050707. Fulltekst i vitenarkiv
• Martinecz, Antal; Clarelli, Fabrizio; Abel, Sören & Abel zur Wiesch, Pia (2019). Reaction Kinetic Models of Antibiotic Heteroresistance. International Journal of Molecular Sciences. ISSN 1422-0067. 20(16). doi: 10.3390/ijms20163965. Fulltekst i vitenarkiv
• Luhr, Morten; Torgersen, Maria Lyngaas; Szalai, Paula; Hashim, Adnan; Brech, Andreas & Stärk, Judith [Vis alle 7 forfattere av denne artikkelen] (2019). The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress. Journal of Biological Chemistry. ISSN 0021-9258. 294(20), s. 8197–8217. doi: 10.1074/jbc.RA118.002829. Fulltekst i vitenarkiv
• Stiksrud, Birgitte; Aass, Hans Christian Dalsbotten; Lorvik, Kristina Berg; Ueland, Thor; Trøseid, Marius & Dyrhol-Riise, Anne Ma (2019). Activated dendritic cells and monocytes in HIV immunological nonresponders: HIV-induced interferon-inducible protein-10 correlates with low future CD4+ recovery. AIDS (London). ISSN 0269-9370. 33(7), s. 1117–1129. doi: 10.1097/QAD.0000000000002173. Fulltekst i vitenarkiv
• Itkonen, Harri; Poulose, Ninu; Walker, Suzanne & Mills, Ian Geoffrey (2019). CDK9 Inhibition Induces a Metabolic Switch that Renders Prostate Cancer Cells Dependent on Fatty Acid Oxidation. Neoplasia. ISSN 1522-8002. 21(7), s. 713–720. doi: 10.1016/j.neo.2019.05.001. Fulltekst i vitenarkiv
• Gupta, Abhay; Gözen, Irep & Taylor, Michael (2019). A cellular automaton for modeling non-trivial biomembrane ruptures. Soft Matter. ISSN 1744-683X. 15(20), s. 4178–4186. doi: 10.1039/c8sm02032a. Fulltekst i vitenarkiv
• Itkonen, Harri; Urbanucci, Alfonso; Sara ES, Martin; Khan, Aziz; Mathelier, Anthony & Thiede, Bernd [Vis alle 8 forfattere av denne artikkelen] (2019). High OGT activity is essential for MYC-driven proliferation of prostate cancer cells. Theranostics. ISSN 1838-7640. 9(8), s. 2183–2197. doi: 10.7150/thno.30834. Fulltekst i vitenarkiv
• Abudu, Yakubu Princely; Pankiv, Serhiy; Mathai, Benan John; Lystad, Alf Håkon; Bindesbøll, Christian & Brenne, Hanne Britt [Vis alle 14 forfattere av denne artikkelen] (2019). NIPSNAP1 and NIPSNAP2 act as “eat-me signal” for mitophagy. Developmental Cell. ISSN 1534-5807. 49(4), s. 509–525.e12. doi: 10.1016/j.devcel.2019.03.013. Fulltekst i vitenarkiv
• Nieoczym, Dorota; Socala, Katarzyna; Gawel, Kinga Aurelia; Esguerra, Camila Vicencio; Wyska, Elzbieta & Wlaz, Piotr (2019). Anticonvulsant Activity of Pterostilbene in Zebrafish and Mouse Acute Seizure Tests. Neurochemical Research. ISSN 0364-3190. 44(5), s. 1043–1055. doi: 10.1007/s11064-019-02735-2. Fulltekst i vitenarkiv
• Engedal, Nikolai; Luhr, Morten; Szalai, Paula & Seglen, Per O. (2019). Measurement of Bulk Autophagy by a Cargo Sequestration Assay. Methods in molecular biology. ISSN 1064-3745. 1880, s. 307–313. doi: 10.1007/978-1-4939-8873-0_20.
• Tepekule, Burcu; Abel zur Wiesch, Pia; Kouyos, Roger D. & Bonhoeffer, Sebastian (2019). Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424. 116(46), s. 23106–23116. doi: 10.1073/pnas.1912188116. Fulltekst i vitenarkiv
• Braadland, Peder Rustøen; Ramberg, Håkon Andre; Grytli, Helene Hartvedt; Urbanucci, Alfonso; Nielsen, Heidi Kristin & Guldvik, Ingrid Jenny [Vis alle 13 forfattere av denne artikkelen] (2019). The β2-adrenergic receptor is a molecular switch for neuroendocrine transdifferentiation of prostate cancer cells. Molecular Cancer Research. ISSN 1541-7786. 17(11), s. 2154–2168. doi: 10.1158/1541-7786.MCR-18-0605.
• Brennecke, Philip; Rasina, Dace; Aubi Catevilla, Oscar; Herzog, Katja; Landskron, Johannes & Cautain, Bastien [Vis alle 42 forfattere av denne artikkelen] (2019). EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology. SLAS Discovery. ISSN 2472-5552. 24(3), s. 398–413. doi: 10.1177/2472555218816276. Fulltekst i vitenarkiv
• Chellappa, Stalin ; Kushekhar, Kushi; Munthe, Ludvig Andre; Tjønnfjord, Geir Erland; Aandahl, Einar Martin & Okkenhaug, Klaus [Vis alle 7 forfattere av denne artikkelen] (2019). The PI3K p110δ isoform inhibitor idelalisib preferentially inhibits human regulatory T cell function. Journal of Immunology. ISSN 0022-1767. 202(5), s. 1397–1405. doi: 10.4049/jimmunol.1701703.
• Subbannayya, Yashwanth; Pinto, Sneha; Bösl, Korbinian; Prasad, T. S. Keshava & Kandasamy, Richard Kumaran (2019). Dynamics of Dual Specificity Phosphatases and Their Interplay with Protein Kinases in Immune Signaling. International Journal of Molecular Sciences. ISSN 1422-0067. 20(9), s. 1–22. doi: 10.3390/ijms20092086. Fulltekst i vitenarkiv
• Köksal, Elif; Belletati, Patrícia Fernandes; Reint, Ganna; Olsson, Ragni; Leitl, Kira & Kantarci, Ilayda [Vis alle 7 forfattere av denne artikkelen] (2019). Spontaneous Formation and Rearrangement of Artificial Lipid Nanotube Networks as a Bottom-Up Model for Endoplasmic Reticulum. Journal of Visualized Experiments. ISSN 1940-087X. 2019(143), s. 1–9. doi: 10.3791/58923. Fulltekst i vitenarkiv
• Kustanovich, Kiryl; Yantchev, Ventsislav; Doosti, Baharan Ali; Gözen, Irep & Jesorka, Aldo (2019). A microfluidics-integrated impedance/surface acoustic resonance tandem sensor. Sensing and Bio-Sensing Research. 25. doi: 10.1016/j.sbsr.2019.100291.
• Joemetsa, Silver; Spustová, Karolina; Kustanovich, Kiryl; Ainla, Alar; Schindler, Severin & Eigler, Siegfried [Vis alle 10 forfattere av denne artikkelen] (2019). Molecular Lipid Films on Microengineering Materials. Langmuir. ISSN 0743-7463. 35(32), s. 10286–10298. doi: 10.1021/acs.langmuir.9b01120.
• Sisodiya, Sanjay M.; Fowler, Hayley J.; Lake, Iain; Nanji, Rosemary Ogwen; Gawel, Kinga Aurelia & Esguerra, Camila Vicencio [Vis alle 8 forfattere av denne artikkelen] (2019). Climate change and epilepsy: Time to take action. Epilepsia Open. ISSN 2470-9239. 4(4), s. 524–536. doi: 10.1002/epi4.12359. Fulltekst i vitenarkiv
• Horowitz, Viva R; Chambers, Zachary C; Gözen, Irep; Dimiduk, Thomas G & Manoharan, Vinothan N (2019). Active colloidal particles in emulsion droplets: a model system for the cytoplasm. The European Physical Journal Special Topics. ISSN 1951-6355. 227(17), s. 2413–2424. doi: 10.1140/epjst/e2019-800026-y.
• Keskitalo, Salla; Haapaniemi, Emma M.; Glumoff, Virpi; Liu, Xiaonan; Lehtinen, Ville & Fogarty, Christopher [Vis alle 16 forfattere av denne artikkelen] (2019). Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease. NPJ GENOMIC MEDICINE. ISSN 2056-7944. 4:14, s. 1–7. doi: 10.1038/s41525-019-0088-5. Fulltekst i vitenarkiv
• Goodridge, Jodie; Jacobs, Benedikt Marcel; Sætersmoen, Michelle Lu; Clement, Dennis; Hammer, Quirin & Clancy, Trevor [Vis alle 24 forfattere av denne artikkelen] (2019). Remodeling of secretory lysosomes during education tunes functional potential in NK cells. Nature Communications. ISSN 2041-1723. 10:14, s. 1–15. doi: 10.1038/s41467-019-08384-x. Fulltekst i vitenarkiv
• Halnes, Geir; Pettersen, Klas Henning; Øyehaug, Leiv; Rognes, Marie Elisabeth & Einevoll, Gaute (2019). Astrocytic Ion Dynamics: Implications for Potassium Buffering and Liquid Flow. I Berry, Hugues & De Pittà, Maurizio (Red.), Computational Glioscience. Springer Nature. ISSN 978-3-030-00817-8. s. 363–391. doi: 10.1007/978-3-030-00817-8_14. Fulltekst i vitenarkiv
• Bernal Mera, Aurora & Arranz, Lorena (2018). Nestin-expressing progenitor cells: function, identity and therapeutic implications. Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 75(12), s. 2177–2195. doi: 10.1007/s00018-018-2794-z. Fulltekst i vitenarkiv
• Colgan, Lesley A; Hu, Mo; Misler, Jaime A; Parra-Bueno, Paula; Moran, Corey M & Leitges, Michael [Vis alle 7 forfattere av denne artikkelen] (2018). PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity. Nature Neuroscience. ISSN 1097-6256. 21(8), s. 1027–1037. doi: 10.1038/s41593-018-0184-3.
• Rogne, Marie; Svärd, Oksana; Madsen-Østerbye, Julia-Kristina Jensen; Hashim, Adnan; Tjønnfjord, Geir Erland & Staerk, Judith (2018). Cytokinesis arrest and multiple centrosomes in B cell chronic lymphocytic leukaemia. Journal of Cellular and Molecular Medicine. ISSN 1582-1838. 22(5), s. 2846–2855. doi: 10.1111/jcmm.13579. Fulltekst i vitenarkiv
• Vorhagen, Susanne; Kleefisch, Dominik; Persa, Oana-Diana; Graband, Annika; Schwickert, Alexandra & Saynisch, Michael [Vis alle 9 forfattere av denne artikkelen] (2018). Shared and independent functions of aPKC? and Par3 in skin tumorigenesis. Oncogene. ISSN 0950-9232. 37, s. 5136–5146. doi: 10.1038/s41388-018-0313-1. Fulltekst i vitenarkiv
• Sugiaman-Trapman, Debora; Vitezic, Morana; Jouhilahti, Eeva-Mari; Mathelier, Anthony; Lauter, Gilbert & Misra, Sougat [Vis alle 9 forfattere av denne artikkelen] (2018). Characterization of the human RFX transcription factor family by regulatory and target gene analysis. BMC Genomics. ISSN 1471-2164. 19(181). doi: 10.1186/s12864-018-4564-6. Fulltekst i vitenarkiv
• Richter, Lisa Maria; Landsverk, Ole J. B.; Atlasy, Nader; Bujko, Anna; Yaqub, Sheraz & Horneland, Rune [Vis alle 12 forfattere av denne artikkelen] (2018). Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine. Mucosal Immunology. ISSN 1933-0219. 11(5), s. 1512–1523. doi: 10.1038/s41385-018-0060-1. Fulltekst i vitenarkiv
• Schwab, Charlotte; Gabrysch, Annemarie; Olbrich, Peter; Patiño, Virginia; Warnatz, Klaus & Wolff, Daniel [Vis alle 81 forfattere av denne artikkelen] (2018). Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects. Journal of Allergy and Clinical Immunology. ISSN 0091-6749. s. 1–15. doi: 10.1016/j.jaci.2018.02.055. Fulltekst i vitenarkiv
• Rogne, Marie; Chu, Dinh Toi; Küntziger, Thomas M.; Mylonakou, Maria-Niki; Collas, Philippe & Tasken, Kjetil (2018). OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells. Molecular Biology of the Cell. ISSN 1059-1524. 29(12), s. 1487–1501. doi: 10.1091/mbc.E17-09-0538. Fulltekst i vitenarkiv
• Grimolizzi, Franco & Arranz , Lorena (2018). Multiple faces of succinate beyond metabolism in blood. Haematologica. ISSN 0390-6078. 103(10), s. 1586–1592. doi: 10.3324/haematol.2018.196097. Fulltekst i vitenarkiv
• Vdovikova, Svitlana; Gilfillan, Siv; Wang, Shixiong; Dongre, Mitesh; Wai, Sun Nyunt & Rodriguez, Antoni Hurtado (2018). Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles. Scientific Reports. ISSN 2045-2322. 8(1). doi: 10.1038/s41598-018-25308-9. Fulltekst i vitenarkiv
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• Nordheim, Espen; Horneland, Rune; Aandahl, Einar Martin; Grzyb, Krzysztof; Aabakken, Lars & Paulsen, Vemund [Vis alle 9 forfattere av denne artikkelen] (2018). Pancreas transplant rejection episodes are not revealed by biopsies of the donor duodenum in a prospective study with paired biopsies. American Journal of Transplantation. ISSN 1600-6135. 18(5), s. 1256–1261. doi: 10.1111/ajt.14658.
• Myhrvold, Ida Kristin; Cremaschi, Andrea; Hermansen, Johanne Uthus; Tjønnfjord, Geir Erland; Munthe, Ludvig Andre & Tasken, Kjetil [Vis alle 7 forfattere av denne artikkelen] (2018). Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia. OncoTarget. ISSN 1949-2553. 9(10), s. 9273–9284. doi: 10.18632/oncotarget.23949. Fulltekst i vitenarkiv
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• Aourz, Najat; Serruys, Ann-Sophie K.; Chabwine, Joelle N.; Balegamire, Pascal Byenda; Afrikanova, Tatiana & Edrada-Ebel, RuAngelie [Vis alle 14 forfattere av denne artikkelen] (2018). Identification of GSK‑3 as a Potential Therapeutic Entry Point for Epilepsy. ACS Chemical Neuroscience. ISSN 1948-7193. doi: 10.1021/acschemneuro.8b00281.
• Hermansen, Johanne Uthus; Tjønnfjord, Geir Erland; Munthe, Ludvig Andre; Tasken, Kjetil & Skånland, Sigrid Strand (2018). Cryopreservation of primary B cells minimally influences their signaling responses. Scientific Reports. ISSN 2045-2322. 8:17651, s. 1–7. doi: 10.1038/s41598-018-36121-9. Fulltekst i vitenarkiv
• Tsui, Carlson; Martínez-Martín, Nuria; Gaya, Mauro; Maldonado, Paula; Llorian, Miriam & Legrave, Nathalie M. [Vis alle 13 forfattere av denne artikkelen] (2018). Protein kinase C-β dictates B cell fate by regulating mitochondrial remodeling, metabolic reprogramming, and heme biosynthesis. Immunity. ISSN 1074-7613. 48(6), s. 1144–1159.e5. doi: 10.1016/j.immuni.2018.04.031. Fulltekst i vitenarkiv
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• Bösl, Korbinian; Ianevski, Aleksandr; Than, Thoa T.; Andersen, Petter I.; Teppor, Mona & Zusinaite, Eva [Vis alle 23 forfattere av denne artikkelen] (2019). Critical Nodes of Viral Modulation Revealed Through an Integrated Network Analysis of Host-Virus Interaction Landscape.
• Sharapova, Svetlana O.; Haapaniemi, Emma; Sakovich, Inga S.; Kostyuchenko, Larysa V.; Donkó, Agnes & Dulau-Florea, Alina [Vis alle 15 forfattere av denne artikkelen] (2019). Heterozygous activating mutation in RAC2 causes infantile-onset combined immunodeficiency with susceptibility to viral infections. Clinical Immunology. ISSN 1521-6616. 205, s. 1–5. doi: 10.1016/j.clim.2019.05.003.
• Tasken, Kjetil (2018). Need for competence and cross-disciplinary efforts between research and clinic in development of precision medicine strategies.
• Tasken, Kjetil (2018). Personalised Cancer Therapies (PerCaThe) – the biological perspectives .
• Luecke, Hartmut (2018). Helicobacter Pylori pH Acclimation: The Evil Duo of a pH-Gated Urea Channel and a Cytoplasmic Urease.
• Luecke, Hartmut (2018). The Evil Duo of a pH-Gated Urea Channel and a Cytoplasmic Urease.
• Luecke, Hartmut (2018). Membrane protein crystallization.
• Luecke, Hartmut (2018). Structure, function, and inhibitors of the Helicobacter pylori acid acclimation system, an essential component for chronic infection.
• Luecke, Hartmut (2018). Cryo EM.
• Luecke, Hartmut (2018). Structure, function, and inhibitors of the Helicobacter pylori acid acclimation system, an essential component for chronic infection.
• Luecke, Hartmut (2018). Structure, function, and inhibitors of the Helicobacter pylori acid acclimation system, an essential component for chronic infection.
• Luecke, Hartmut (2018). Structure, function, and inhibitors of the Helicobacter pylori acid acclimation system, an essential component for chronic infection.
• Luecke, Hartmut (2018). Survival of Helicobacter pylori at pH 1 in the stomach.
• Luecke, Hartmut (2018). Membrane protein crystallization.
• Awuh, Jane Atesoh & Flo, Trude Helen (2018). Erratum to: Molecular basis of mycobacterial survival in macrophages (Cellular and Molecular Life Sciences, (2017), 74, 9, (1625-1648), 10.1007/s00018-016-2422-8). Cellular and Molecular Life Sciences (CMLS). ISSN 1420-682X. 75(1), s. 161–161. doi: 10.1007/s00018-017-2683-x.

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