We want to improve our understanding of the pathophysiological events underlying acute ischemic injury of the heart and the subsequent remodelling which may lead to heart failure. We work towards identifying new therapeutic targets to reduce these injuries. We also work to improve organs for transplantation with focus in ischemia reperfusion injury.
Illustration: Colourbox.no
The group uses human material, mouse, rat and pig models of ischemic heart disease with functional evaluation (echocardiography and pressure-volume loops, Langendorff perfusion) combined with tissue analysis, and cell- and molecular biology as supplements to reach our aims.
Photo by Jonas Carlsen